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carbachol and Adenocarcinoma

carbachol has been researched along with Adenocarcinoma in 27 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"We have previously reported that breast tumors highly express functional muscarinic acetylcholine receptors (mAChRs) that regulate tumor progression."5.42Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase. ( Español, AJ; Rojo, D; Salem, A; Sales, ME, 2015)
"Carbachol was used to induce SOCE in Fura 2-loaded HT29 cells."5.38Oleic acid inhibits store-operated calcium entry in human colorectal adenocarcinoma cells. ( Alonso-Torre, SR; Carrillo, C; Cavia, Mdel M, 2012)
" We studied the action of a combination of low doses of the muscarinic agonist carbachol plus paclitaxel, a chemotherapeutic agent frequently used in breast cancer treatment, in terms of effectiveness."3.79Muscarinic activation enhances the anti-proliferative effect of paclitaxel in murine breast tumor cells. ( Dmytrenko, G; Español, AJ; Jacob, G; Sales, ME, 2013)
" Short-circuit current (I(SC)) responses to carbachol (CCh) were investigated in Colony 1 epithelia, a subpopulation of the HCA-7 adenocarcinoma cell line."3.70Modulation of chloride, potassium and bicarbonate transport by muscarinic receptors in a human adenocarcinoma cell line. ( Cox, HM; Holliday, ND, 1999)
"Cells of the HSG cell line derived from a human submandibular gland adenocarcinoma and those of the A-431 human epidermoid carcinoma cell line were loaded with a fluorescent pH indicator, BCECF/AM, and the change in the intracellular pH of adherent cells and suspended ones were measured following stimulation with various concentrations (10(-7) M to 10(-2) M) of neurotransmitters (carbachol, noradrenaline, and isoproterenol)."3.70Alkalization produced by high-dose carbachol in HSG cell line is independent of Ca2+. ( Atsumi, T; Iwakura, I; Ueha, T, 1998)
" This study used an in vitro model of colonic secretion, monolayers of T84 colonic adenocarcinoma cells mounted in Ussing chambers, to demonstrate that 100 mumol/L of either tangeritin or nobiletin, polymethoxylated flavonoids contained in citrus fruits, stimulated sustained electrogenic chloride secretion with a maximal short-circuit current of 3."3.68Citrus flavonoids stimulate secretion by human colonic T84 cells. ( Canada, AT; Nguyen, TD, 1993)
"Ornithine decarboxylase in a human parotid gland adenocarcinoma cell line was induced by both cholinergic (carbachol) and beta-adrenergic (isoproterenol) sialagogues."3.68Induction of ornithine decarboxylase by sialagogues in a human parotid gland adenocarcinoma cell line. ( Ashida, Y; Inoue, H; Kawano, M; Kinoshita, F; Ueno, A, 1991)
"Addition of the cholinergic agents acetylcholine or carbamylcholine (CCh) to suspensions of human endometrial adenocarcinoma cells (Ishikawa line) preincubated with [3H] myoinositol promoted a rapid concentration-dependent hydrolysis of labeled phosphoinositides to inositol tris-, bis-, and monophosphates with EC50 values (mean +/- SE) of 3."3.67Regulation of phosphoinositide hydrolysis in transformed human endometrial cells. ( Gurpide, E; Weiss, DJ, 1988)
"We have previously reported that breast tumors highly express functional muscarinic acetylcholine receptors (mAChRs) that regulate tumor progression."1.42Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase. ( Español, AJ; Rojo, D; Salem, A; Sales, ME, 2015)
"Carbachol was used to induce SOCE in Fura 2-loaded HT29 cells."1.38Oleic acid inhibits store-operated calcium entry in human colorectal adenocarcinoma cells. ( Alonso-Torre, SR; Carrillo, C; Cavia, Mdel M, 2012)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's13 (48.15)18.2507
2000's5 (18.52)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Español, AJ2
Salem, A1
Rojo, D1
Sales, ME5
Toumi, F1
Frankson, M1
Ward, JB1
Kelly, OB1
Mroz, MS1
Bertelsen, LS1
Keely, SJ1
Carrillo, C1
Cavia, Mdel M1
Alonso-Torre, SR1
Sung, EZ1
Arasaradnam, RP1
Jarvie, EM1
James, S1
Goodyear, SJ1
Borman, RA1
Snead, D1
Sanger, GJ1
Nwokolo, CU1
Jacob, G1
Dmytrenko, G1
Fiszman, G1
Cattaneo, V1
de la Torre, E2
Español, A2
Colombo, L1
Sacerdote de Lustig, E2
Hattori, T1
Wang, PL1
Genaro, AM1
Ribeiro, ML1
Pagotto, R1
Pignataro, OP1
McCool, DJ2
Forstner, JF2
Forstner, GG2
Warhurst, G1
Fogg, KE1
Higgs, NB1
Tonge, A1
Grundy, J1
Stenson, WF1
Easom, RA1
Riehl, TE1
Turk, J1
Nguyen, TD2
Canada, AT2
Montserrat, C1
Merten, M1
Figarella, C1
Seghieri, P1
Dussert, C1
Palmari, J1
Berthois, Y1
Martin, PM1
Penel, C1
Holliday, ND1
Cox, HM1
Atsumi, T1
Iwakura, I1
Ueha, T1
Sun, X1
Liu, XB1
Martinez, JR1
Dang, H1
Zhang, GH1
Eiján, AM1
Mazzoni, E1
Davel, L1
Jasnis, MA1
Ueno, A1
Kawano, M1
Ashida, Y1
Kinoshita, F1
Inoue, H1
Patton, LL1
Pollack, S1
Wellner, RB1
Wu, H1
Franklin, CC1
Kim, HD1
Turner, JT1
Marcon, MA1
Taton, G1
Delhaye, M1
Swillens, S1
Morisset, J1
Larose, L1
Longnecker, DS1
Poirier, GG1
Weiss, DJ1
Gurpide, E1
Phillips, TE1
Huet, C2
Bilbo, PR1
Podolsky, DK1
Louvard, D2
Neutra, MR1
Sahuquillo-Merino, C1
Coudrier, E1

Other Studies

27 other studies available for carbachol and Adenocarcinoma

ArticleYear
Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase.
    International immunopharmacology, 2015, Volume: 29, Issue:1

    Topics: Adenocarcinoma; Arginase; Breast Neoplasms; Carbachol; Cell Line, Tumor; Drug Therapy, Combination;

2015
Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Calcium; Carbachol; Cell Line, Tumor; Chlorides; Colforsin; Colonic Neoplasms; Epith

2011
Oleic acid inhibits store-operated calcium entry in human colorectal adenocarcinoma cells.
    European journal of nutrition, 2012, Volume: 51, Issue:6

    Topics: Adenocarcinoma; Biological Transport; Calcium Signaling; Calcium-Transporting ATPases; Calcium, Diet

2012
Effects of neo-adjuvant chemotherapy for oesophago-gastric cancer on neuro-muscular gastric function.
    Molecular biology reports, 2012, Volume: 39, Issue:12

    Topics: Acetylcholinesterase; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecita

2012
Muscarinic activation enhances the anti-proliferative effect of paclitaxel in murine breast tumor cells.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carbachol; Cell Line,

2013
Muscarinic receptors autoantibodies purified from mammary adenocarcinoma-bearing mice sera stimulate tumor progression.
    International immunopharmacology, 2006, Volume: 6, Issue:8

    Topics: Adenocarcinoma; Animals; Atropine; Autoantibodies; Blotting, Western; Carbachol; Cell Line, Tumor; C

2006
Calcium antagonists cause dry mouth by inhibiting resting saliva secretion.
    Life sciences, 2007, Aug-02, Volume: 81, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2007
Proliferative actions of muscarinic receptors expressed in macrophages derived from normal and tumor bearing mice.
    Biochimica et biophysica acta, 2008, Volume: 1782, Issue:2

    Topics: Adenocarcinoma; Animals; Arginase; Carbachol; Cell Line, Tumor; Cell Proliferation; Female; Macropha

2008
Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.
    The Biochemical journal, 1995, Nov-15, Volume: 312 ( Pt 1)

    Topics: Adenocarcinoma; Biomarkers, Tumor; Calcimycin; Carbachol; Cell Size; Colchicine; Colonic Neoplasms;

1995
Ca(2+)-mobilising agonists potentiate forskolin- and VIP-stimulated cAMP production in human colonic cell line, HT29-cl.19A: role of [Ca2+]i and protein kinase C.
    Cell calcium, 1994, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Calcium; Calmodulin; Carbachol; Colforsin; Colonic Neoplasms; Cyclic AMP; Drug Syner

1994
Regulation of paracellular permeability in Caco-2 cell monolayers by protein kinase C.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Adenocarcinoma; Alkaloids; Carbachol; Cell Line; Cell Membrane; Cell Membrane Permeability; Colonic

1993
Modulation of human colonic T84 cell secretion by hydrogen peroxide.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Carbachol; Catalase; Chlorides; Colonic Neoplasms; Deferoxamine; Dithiothreitol; Ele

1994
Citrus flavonoids stimulate secretion by human colonic T84 cells.
    The Journal of nutrition, 1993, Volume: 123, Issue:2

    Topics: Adenocarcinoma; Carbachol; Chlorides; Citrus; Colon; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Drug

1993
Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells.
    FEBS letters, 1996, Sep-16, Volume: 393, Issue:2-3

    Topics: Adenocarcinoma; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; A

1996
A minimal model for calcium signal generated by tyrosine kinase and G protein linked receptors; a stochastic computer simulation with CALSIM.
    International journal of medical informatics, 1997, Volume: 46, Issue:1

    Topics: Adenocarcinoma; Algorithms; Calcium; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Cell

1997
Modulation of chloride, potassium and bicarbonate transport by muscarinic receptors in a human adenocarcinoma cell line.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: Acetazolamide; Adenocarcinoma; Barium; Bicarbonates; Biological Transport; Carbachol; Carbonic Anhyd

1999
Alkalization produced by high-dose carbachol in HSG cell line is independent of Ca2+.
    Oral diseases, 1998, Volume: 4, Issue:4

    Topics: Acid-Base Equilibrium; Adenocarcinoma; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Calcium

1998
Effects of radiation on Ca2+ signaling in salivary epithelial cell lines transfected with Bcl-2 and Bcl-XL.
    European journal of oral sciences, 2001, Volume: 109, Issue:2

    Topics: Adenocarcinoma; bcl-X Protein; Calcium; Calcium Signaling; Carbachol; Cholinergic Agonists; Epitheli

2001
Nitric oxide synthase, arginase and cyclooxygenase are involved in muscarinic receptor activation in different murine mammary adenocarcinoma cell lines.
    International journal of molecular medicine, 2002, Volume: 9, Issue:6

    Topics: Adenocarcinoma; Animals; Arginase; Blotting, Western; Carbachol; Cell Division; Dinoprostone; Dose-R

2002
Induction of ornithine decarboxylase by sialagogues in a human parotid gland adenocarcinoma cell line.
    Biochemistry international, 1991, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Carbachol; Cell Division; Enzyme Induction; Gene Expression Regulation, Enzymologic;

1991
Responsiveness of a human parotid epithelial cell line (HSY) to autonomic stimulation: muscarinic control of K+ transport.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1991, Volume: 27A, Issue:10

    Topics: Adenocarcinoma; Atropine; Biological Transport, Active; Carbachol; Cell Line; Epinephrine; Epitheliu

1991
Regulation of calcium-activated potassium efflux by neurotensin and other agents in HT-29 cells.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 1

    Topics: Adenocarcinoma; Adenosine Triphosphate; Barium; Calcium; Carbachol; Cell Line; Colonic Neoplasms; Hu

1991
The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues.
    The Biochemical journal, 1990, Apr-15, Volume: 267, Issue:2

    Topics: Adenocarcinoma; Calcimycin; Carbachol; Cell Line; Cholera Toxin; Colonic Neoplasms; Cystic Fibrosis;

1990
Muscarinic cholinergic receptors in pancreatic acinar carcinoma of rat.
    International journal of cancer, 1985, Apr-15, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Amylases; Animals; Atropine; Binding, Competitive; Carbachol; Carcinoma; Dexetimide;

1985
Regulation of phosphoinositide hydrolysis in transformed human endometrial cells.
    Endocrinology, 1988, Volume: 123, Issue:2

    Topics: Acetylcholine; Adenocarcinoma; Atropine; Carbachol; Cell Differentiation; Chlorides; Endometrium; Fe

1988
Human intestinal goblet cells in monolayer culture: characterization of a mucus-secreting subclone derived from the HT29 colon adenocarcinoma cell line.
    Gastroenterology, 1988, Volume: 94, Issue:6

    Topics: Adenocarcinoma; Carbachol; Cell Differentiation; Cell Line; Clone Cells; Colonic Neoplasms; Culture

1988
Absorptive and mucus-secreting subclones isolated from a multipotent intestinal cell line (HT-29) provide new models for cell polarity and terminal differentiation.
    The Journal of cell biology, 1987, Volume: 105, Issue:1

    Topics: Adenocarcinoma; Carbachol; Cell Differentiation; Cell Line; Clone Cells; Colonic Neoplasms; Cytoplas

1987