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carbachol and Acute Edematous Pancreatitis

carbachol has been researched along with Acute Edematous Pancreatitis in 22 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Research Excerpts

ExcerptRelevanceReference
" Two kinds of pancreatic secretagogues, one category of which induces acute pancreatitis (cholecystokinin and carbachol) and another which does not induce acute pancreatitis (bombesin, CCK-JMV-180, and secretin), as well as lecithin were used to investigate the effect of changes in membrane fluidity of acini."3.69Effects of cholecystokinin and carbachol on membrane fluidity in pancreatic acini. ( Arii, S; Funaki, N; Imamura, M; Imamura, T; Kohmoto, M; Ohshio, G; Okada, N; Sasaoki, T; Tanaka, J; Tanaka, T; Wang, ZH; Yoshida, M, 1996)
"These results support the hypothesis that increased intracellular trypsinogen activation is an early step in the pathogenesis of hypercalcaemia induced pancreatitis."3.69Elevated calcium and activation of trypsinogen in rat pancreatic acini. ( Bimmler, D; Fernández-del Castillo, C; Frick, TW; Warshaw, AL, 1997)
"Young female mice fed a choline-deficient, ethionine-supplemented (CDE) diet rapidly develop acute hemorrhagic pancreatitis."3.67Diminished agonist-stimulated inositol trisphosphate generation blocks stimulus-secretion coupling in mouse pancreatic acini during diet-induced experimental pancreatitis. ( Houlihan, MJ; Powers, RE; Saluja, AK; Steer, ML, 1986)
"Acute pancreatitis is a disease associated with inflammation and tissue damage."1.46The serum protein renalase reduces injury in experimental pancreatitis. ( Chung, SL; Date, K; Desir, GV; Gorelick, FS; Kolodecik, TR; Patel, V; Reed, AM; Shugrue, CA, 2017)
"Pancreatitis is a necroinflammatory disease with acute and chronic manifestations."1.40Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis. ( Aronson, JF; Bhatia, V; Falzon, M; Greeley, GH; Han, S; Rastellini, C, 2014)
"h-1) evoked a characteristic biphasic dose-response curve for pancreatic juice and protein output in the LETO rats, whereas the OLETF rats were totally insensitive to CCK-8 stimulation."1.29Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats. ( Akiyama, T; Furumi, K; Kanagawa, K; Otsuki, M; Shiohara, H; Tachibana, I; Watanabe, N, 1996)
"Acute edematous pancreatitis was produced in rats by subcutaneous administration of caerulein."1.28Prevention by prostaglandins of caerulein-induced pancreatitis in rats. ( Kolbasa, KP; Lancaster, C; Lum, JT; Nezamis, JE; Olafsson, AS; Robert, A, 1989)
"This oedema is largely reabsorbed after 24 h treatment, but the pancreas is considerably indurated by this time."1.26Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue. ( Kern, HF; Lampel, M, 1977)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19908 (36.36)18.7374
1990's6 (27.27)18.2507
2000's5 (22.73)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kolodecik, TR2
Reed, AM1
Date, K1
Shugrue, CA1
Patel, V1
Chung, SL1
Desir, GV1
Gorelick, FS2
Bhatia, V1
Rastellini, C1
Han, S1
Aronson, JF1
Greeley, GH1
Falzon, M1
Yuan, J2
Lugea, A1
Zheng, L1
Gukovsky, I1
Edderkaoui, M1
Rozengurt, E1
Pandol, SJ2
Bhoomagoud, M1
Jung, T1
Atladottir, J1
Shugrue, C1
Chaudhuri, A1
Thrower, EC2
Kim, MS1
Hong, JH1
Li, Q1
Shin, DM1
Abramowitz, J1
Birnbaumer, L1
Muallem, S1
Usmani, A1
Liu, Y1
Jones, C1
Minervini, SN1
Alexandre, M1
Guha, S1
Zheng, H1
Chen, D1
Zhang, J1
Tian, Y1
Blomfield, J1
Settree, PJ1
Allars, HM1
Rush, AR1
Evander, A1
Lundquist, I1
Ihse, I1
Grönroos, JM1
Laine, J1
Kaila, T1
Nevalainen, TJ1
Wang, ZH1
Ohshio, G1
Okada, N1
Imamura, T1
Tanaka, T1
Kohmoto, M1
Yoshida, M1
Tanaka, J1
Arii, S1
Sasaoki, T1
Funaki, N1
Imamura, M1
Tachibana, I1
Akiyama, T1
Kanagawa, K1
Shiohara, H1
Furumi, K1
Watanabe, N1
Otsuki, M1
Frick, TW1
Fernández-del Castillo, C1
Bimmler, D1
Warshaw, AL1
Chen, JW1
Thomas, A1
Woods, CM1
Schloithe, AC1
Toouli, J1
Saccone, GT1
Aĭdarov, MA1
Bazarevich, GIa1
Grigorenko, SG1
Kosheleva, DK1
Tereshchenko, VIu1
Lampel, M1
Kern, HF1
Elizarova, SS1
Lebedev, NN1
Keim, V1
Bilchik, AJ1
Zucker, KA1
Adrian, TE1
Modlin, IM1
Powers, RE1
Saluja, AK1
Houlihan, MJ1
Steer, ML1
Morisset, J1
Wood, J1
Solomon, TE1
Larose, L1
Robert, A1
Lum, JT1
Lancaster, C1
Olafsson, AS1
Kolbasa, KP1
Nezamis, JE1

Other Studies

22 other studies available for carbachol and Acute Edematous Pancreatitis

ArticleYear
The serum protein renalase reduces injury in experimental pancreatitis.
    The Journal of biological chemistry, 2017, 12-22, Volume: 292, Issue:51

    Topics: Acinar Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Calcium Signaling; Carba

2017
Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Sep-01, Volume: 307, Issue:5

    Topics: Acinar Cells; Amylases; Animals; Carbachol; Cells, Cultured; Ceruletide; Fibrosis; Humans; Inflammat

2014
Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:6

    Topics: Animals; Carbachol; Ceruletide; Cholecystokinin; Cholinergic Agonists; Mice; NF-kappa B; Pancreas, E

2008
Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adenosine Triphosphatases; Amylases; Animals; Carbachol; Ceruletide; Chymotrypsin; Enzyme Activation

2009
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis.
    Gastroenterology, 2009, Volume: 137, Issue:4

    Topics: Actins; Acute Disease; Animals; Calcium Signaling; Carbachol; Ceruletide; Cholinergic Agonists; Dise

2009
A novel protein kinase D inhibitor attenuates early events of experimental pancreatitis in isolated rat acini.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 300, Issue:1

    Topics: Animals; Carbachol; Carbazoles; Cathepsin B; Cholecystokinin; Male; NF-kappa B; Pancreatitis; Phosph

2011
Involvement of M3 cholinergic receptor signal transduction pathway in regulation of the expression of chemokine MOB-1, MCP-1 genes in pancreatic acinar cells.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2004, Volume: 24, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Carbachol; Carrier Proteins; Chemokine CCL2; Chemokines; Human

2004
Ultrastructural changes in the sheep pancreas stimulated in vivo by secretin, cholecystokinin, and carbachol.
    Experimental and molecular pathology, 1982, Volume: 36, Issue:2

    Topics: Amylases; Animals; Carbachol; Cholecystokinin; Chronic Disease; Enzyme Precursors; Female; Microscop

1982
Hormonal and cholinergic effects on amylase and lysosomal enzyme activities in pancreatic tissue and ascites of rats with acute experimental pancreatitis.
    The Journal of surgical research, 1983, Volume: 35, Issue:2

    Topics: Acetylglucosaminidase; Acid Phosphatase; Acute Disease; Amylases; Animals; Ascitic Fluid; Carbachol;

1983
Chronic alcohol intake and carbachol-induced acute pancreatitis in the rat.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:2

    Topics: Acute Disease; Alcoholism; Animals; Carbachol; Male; Pancreatitis; Phospholipases A; Rats; Rats, Spr

1994
Effects of cholecystokinin and carbachol on membrane fluidity in pancreatic acini.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:7

    Topics: Animals; Bombesin; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Hormone Antagonists

1996
Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 1

    Topics: Acute Disease; Animals; Carbachol; Caseins; Ceruletide; Cholecystokinin; Duodenum; Gastric Acid; Glu

1996
Elevated calcium and activation of trypsinogen in rat pancreatic acini.
    Gut, 1997, Volume: 41, Issue:3

    Topics: Acute Disease; Animals; Calcium; Carbachol; Ceruletide; Culture Techniques; Enzyme Activation; Enzym

1997
Sphincter of Oddi dysfunction produces acute pancreatitis in the possum.
    Gut, 2000, Volume: 47, Issue:4

    Topics: Acute Disease; Amylases; Animals; Carbachol; Female; Ligation; Male; Opossums; Pancreatitis; Sincali

2000
[Neurohumoral correlations and the effect of hydrocortisone on respiratory function in experimental pancreatitis].
    Vestnik khirurgii imeni I. I. Grekova, 1978, Volume: 120, Issue:6

    Topics: Acute Disease; Animals; Blood Pressure; Carbachol; Dogs; Drug Therapy, Combination; Humans; Hydrocor

1978
Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue.
    Virchows Archiv. A, Pathological anatomy and histology, 1977, Mar-11, Volume: 373, Issue:2

    Topics: Acute Disease; Amylases; Animals; Carbachol; Ceruletide; Edema; Male; Microscopy, Electron; Pancreas

1977
[Role of intestinal hormones in the pathogenesis of experimental pancreatitis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 86, Issue:9

    Topics: Amylases; Animals; Carbachol; Cholecystokinin; Dogs; Gastric Juice; Gastric Mucosa; Histamine; Lipas

1978
[Intracellular activation of pancreatic proenzyme as a physiologic process?].
    Zeitschrift fur Gastroenterologie, 1992, Volume: 30, Issue:3

    Topics: Acute Disease; Animals; Carbachol; Ceruletide; Culture Techniques; Enzyme Precursors; Pancreas; Panc

1992
Amelioration of cholinergic-induced pancreatitis with a selective cholecystokinin receptor antagonist.
    Archives of surgery (Chicago, Ill. : 1960), 1990, Volume: 125, Issue:12

    Topics: Acute Disease; Animals; Benzodiazepinones; Carbachol; Cholecystokinin; Cytoplasm; Devazepide; Endopl

1990
Diminished agonist-stimulated inositol trisphosphate generation blocks stimulus-secretion coupling in mouse pancreatic acini during diet-induced experimental pancreatitis.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:5

    Topics: Aminoquinolines; Amylases; Animals; Calcimycin; Calcium; Carbachol; Choline Deficiency; Diglycerides

1986
Muscarinic receptors and amylase secretion of rat pancreatic acini during cerulein-induced acute pancreatitis.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:8

    Topics: Acute Disease; Amylases; Animals; Carbachol; Ceruletide; Male; Pancreas; Pancreatitis; Rats; Rats, I

1987
Prevention by prostaglandins of caerulein-induced pancreatitis in rats.
    Laboratory investigation; a journal of technical methods and pathology, 1989, Volume: 60, Issue:5

    Topics: 16,16-Dimethylprostaglandin E2; Amylases; Animals; Carbachol; Ceruletide; Cholecystokinin; Dinoprost

1989