captopril has been researched along with Fibrosis in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.13) | 18.7374 |
| 1990's | 8 (12.50) | 18.2507 |
| 2000's | 26 (40.63) | 29.6817 |
| 2010's | 24 (37.50) | 24.3611 |
| 2020's | 4 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Hou, Y; Huang, F; Lin, J; Ye, Z; Yuan, Z; Zhang, E; Zhou, L | 1 |
| Aras, O; Brown, S; Campbell, A; Gardenier, J; Hespe, GE; Kataru, RP; Kuonqui, K; Li, C; Ly, C; Mehrara, BJ; Nores, GDG; Park, HJ; Sarker, A; Shin, J | 1 |
| Cao, X; Chen, G; Hu, G; Li, J; Liu, W; Peng, C; Peng, F; Xiaofang, X | 1 |
| Gao, X; Ge, X; Jin, F; Li, S; Li, Y; Mao, N; Wei, Z; Xu, H; Yang, F; Yang, Y; Zhang, M; Zhang, Y | 1 |
| Chu, L; Han, X; Li, P; Liu, T; Song, Q; Song, T; Zhang, J; Zhang, X; Zhang, Y | 1 |
| Adamcova, M; Aziriova, S; Balazova, L; Celec, P; Krajcirovicova, K; Pechanova, O; Repova, K; Simko, F; Tothova, L; Vrankova, S; Zorad, S | 1 |
| Ebrahimzadeh Bideskan, A; Hosseinian, S; Khajavi Rad, A; Sadeghnia, HR; Samadi Noshahr, Z; Shafei, MN; Shahraki, S; Soukhtanloo, M | 1 |
| Askari, VR; Boskabadi, J; Boskabady, MH; Hosseini, M | 1 |
| Jia, CH; Shen, W; Wang, J; Xie, ML; Zhang, JY | 1 |
| Tofield, A | 1 |
| Fish, BL; Gao, F; Jacobs, ER; Lazarova, Z; Medhora, M; Moulder, JE; Narayanan, J; Schock, A; Szabo, A | 1 |
| Chai, X; Han, J; Li, C; Qiu, Q; Shi, T; Wang, W; Wang, Y; Wu, Y | 1 |
| Becerril, C; Checa, M; Díaz-Piña, G; García de Alba, C; Montes, E; Ordoñez-Razo, R; Páramo, I; Ruiz, V; Vega, A | 1 |
| Chan, GC; Huang, XR; Lan, HY; Lin, M; Tang, SC; Wong, DW; Wu, HJ; Yiu, WH | 1 |
| Cohen, EP; Falck, JR; Fish, B; Hye Khan, MA; Imig, JD; Moulder, JE; Paudyal, MP; Sharma, A; Wahl, G | 1 |
| Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA | 1 |
| Chan, GCW; Chan, KW; Huang, XR; Lai, KN; Lan, HY; Tang, SCW; Wu, HJ; Yiu, WH; Zou, A | 1 |
| Li, XL; Sha, NN; Shi, Q; Shu, B; Wang, XL; Wang, YJ; Wong, MS; Xiao, HH; Zhang, Y; Zhao, YJ | 1 |
| Li, B; Liu, Y; Wei, J; Xu, H; Zhou, F | 1 |
| Hara, Y; Harada, T; Hori, Y; Kikuzuki, R; Okada, M; Yamawaki, H | 1 |
| Blankesteijn, WM; Daemen, MJ; Fujimoto, A; Fujimoto, S; Hofstra, L; Isobe, S; Li, P; Lovhaug, D; Narula, J; Narula, N; Petrov, A; Pitt, B; Reutelingsperger, C; Smits, JF; van den Borne, SW; Vannan, MA; Wong, ND; Zandbergen, HR; Zannad, F | 1 |
| Enjamoori, R; Jaiswal, A; Kumar, S; Maulik, SK; Ray, R; Seth, S | 1 |
| Guo, C; Liang, H; Wang, Y; Zhang, J | 1 |
| Chen, Y; Fang, YN; Guo, CY; Li, Q; Wang, Y | 1 |
| Hara, Y; Hoshino, Y; Kosaka, N; Okada, M; Yamawaki, H | 1 |
| Babál, P; Hlavačková, L; Janega, P; Pecháňová, O; Vranková, S | 1 |
| Cai, Y; Jia, LX; Qi, YF; Tang, CS; Wang, X; Wu, SY; Xiao, CS; Yu, YR | 1 |
| Fish, BL; Gao, F; Jacobs, ER; Kma, L; Medhora, M; Moulder, JE | 1 |
| Bechtel, W; Bey, P; Bosukonda, D; Carlson, W; Kalluri, R; Kanasaki, K; Keck, P; LeBleu, VS; Okada, H; Rusckowski, M; Sugimoto, H; Taduri, G; Tampe, B; Tampe, D; Zeisberg, M | 1 |
| Chen, CC; Dahly-Vernon, AJ; Dunn, KM; Ledbetter, SR; Murphy, SR; Roman, RJ; Williams, JM | 1 |
| Chen, H; Chen, Q; Chen, Y; Huang, Y; Pan, J; Xue, W | 1 |
| Engman, DM; Leon, JS; Wang, K | 1 |
| Bauer, JA; Ghosh, S; Holycross, BJ; Kambara, A; Kwiatkowski, P; McCune, SA; Schanbacher, B; Wung, P | 1 |
| Boffa, JJ; Chansel, D; Chatziantoniou, C; Dussaule, JC; Flamant, M; Vandermeersch, S; Ying, L | 1 |
| Adam, A; Blais, C; Clément, R; Deschepper, CE; Lapointe, N; Parker, TG; Rouleau, D; Rouleau, JL; Slaughter, G; Tsoporis, JN | 1 |
| Brigstock, DR; Carretero, OA; Cavasin, MA; Peng, H; Rasoul, S; Rhaleb, NE; Sanchez-Mendoza, A; Zhuo, J | 1 |
| Arteel, GE; Bradford, BU; Froh, M; Gäbele, E; Ikai, I; Isayama, F; Uesugi, T; Yamaoka, Y | 1 |
| Faitelson, Y; Goldin, E; Latella, G; Pappo, O; Pines, M; Sestieri, M; Villanova, A; Wengrower, D; Zannineli, G; Zanninelli, G | 1 |
| Godes, M; Hocher, B; Neumayer, HH; Richter, CM; Simon, K; Thöne-Reinke, C; Thormählen, D | 1 |
| Balding, LC; Burns, WC; Burrell, LM; Candido, R; Cao, Z; Dean, RG; Twigg, SM | 1 |
| Arnold, N; Marx, G; Rassler, B; Tannapfel, A; Ziegelhöffer-Mihalovicova, B; Zimmer, HG | 1 |
| Carretero, OA; Liao, TD; Peng, H; Peterson, EL; Rhaleb, NE | 1 |
| Bahri, MA; Noorafshan, A; Shirazi, M; Tanideh, N | 1 |
| Ahn, SC; Baik, SK; Cho, MY; Choi, YH; Kim, CH; Kim, JW; Kim, MY; Kwon, SO; Park, DH; Rhim, DW | 1 |
| Hassanpour, A; Khezri, A; Kojoori, J; Monabbati, A; Samani, SM; Shirazi, M | 1 |
| Kroup, M; Noorafshan, A; Shirazi, M; Tanideh, N | 1 |
| Pandey, KN; Somanna, N; Vellaichamy, E; Zhao, D | 1 |
| Bahk, TJ; Daniels, MD; Engman, DM; Leon, JS; Wang, K | 1 |
| Genade, S; Harper, IS; Lochner, A; Madhoo, J; Salie, R; van Schalkwyk, D; Williams, K; Wynchank, S; Yarom, R | 1 |
| Anderson, PG; Berecek, KH; Bishop, SP; Regan, CP | 1 |
| Fogo, A; Freeman, M; Lo, W; Oikawa, T; Vaughan, DE | 1 |
| Gomes, MG; Milanez, MC; Mill, JG; Vassallo, DV | 1 |
| Joshi, I; Pardo, A; Ramos, C; Selman, M; Uhal, BD; Wang, R; Zagariya, A | 1 |
| Cruz, CI; del Moral, RG; Rodríguez-Puyol, D; Rodríguez-Puyol, M; Ruiz-Torres, P | 1 |
| Brilla, CG | 1 |
| Hata, A; Ikeda, Y; Kimura, H; Mochizuki, S; Nakamura, T; Obata, JE; Shido, K; Takano, H; Takeda, S; Yoshida, Y | 1 |
| Burrell, LM; Farina, NK; Johnston, CI | 1 |
| Cohen, EP; Fish, BL; Molteni, A; Moulder, JE; Taylor, JM; Veno, PA; Ward, WF; Wolfe, LF | 1 |
| Griffiths, NM; Naftalin, RJ; Pedley, KC; Thiagarajah, JR | 1 |
| Anversa, P; Armstrong, PW; Brilla, CG; Burnett, JC; Cruickshank, JM; Devereux, RB; Giles, TD; Korsgaard, N; Leier, CV; Weber, KT | 1 |
| Jalil, JE; Janicki, JS; Pick, R; Tan, LB; Weber, KT | 1 |
| Jalil, JE; Janicki, JS; Pick, R; Weber, KT | 1 |
| Hashimoto, K; Hayashi, Y; Imai, K; Yoshimura, S | 1 |
| DiBona, GF; Jones, S; Koepke, JP | 1 |
1 review(s) available for captopril and Fibrosis
| Article | Year |
|---|---|
Remodeling and reparation of the cardiovascular system.
Topics: Animals; Blood Pressure; Captopril; Cardiomegaly; Collagen; Coronary Circulation; Diabetic Angiopathies; Endothelins; Endothelium, Vascular; Fibrosis; Heart; Heart Failure; Humans; Hypertension; Hypertension, Renovascular; Muscle, Smooth, Vascular; Myocardium; Peptidyl-Dipeptidase A; Rats; Vascular Resistance | 1992 |
1 trial(s) available for captopril and Fibrosis
| Article | Year |
|---|---|
Effect of intraurethral captopril gel on the recurrence of urethral stricture after direct vision internal urethrotomy: Phase II clinical trial.
Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Fibrosis; Follow-Up Studies; Gels; Humans; Instillation, Drug; Male; Middle Aged; Retrospective Studies; Secondary Prevention; Treatment Outcome; Urethra; Urethral Stricture; Urologic Surgical Procedures, Male | 2007 |
62 other study(ies) available for captopril and Fibrosis
| Article | Year |
|---|---|
Co-Delivery of Dexamethasone and Captopril by α8 Integrin Antibodies Modified Liposome-PLGA Nanoparticle Hybrids for Targeted Anti-Inflammatory/Anti-Fibrosis Therapy of Glomerulonephritis.
Topics: Animals; Anti-Inflammatory Agents; Antibodies; Captopril; Dexamethasone; Fibrosis; Glomerulonephritis; Integrins; Liposomes; Mice; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer | 2022 |
Topical captopril: a promising treatment for secondary lymphedema.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Fibrosis; Lymphedema; Mice; Transforming Growth Factor beta1 | 2023 |
Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway.
Topics: Animals; Captopril; Female; Fibrosis; Hypertension; Hypertension, Renal; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Olive Oil; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; RNA, Messenger; Transforming Growth Factor beta1 | 2023 |
N-Acetyl-Seryl-Asparyl-Lysyl-Proline regulates lung renin angiotensin system to inhibit epithelial-mesenchymal transition in silicotic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Epithelial-Mesenchymal Transition; Fibrosis; Losartan; Lung; Male; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Silicosis | 2020 |
Protective effects of tannic acid on pressure overload-induced cardiac hypertrophy and underlying mechanisms in rats.
Topics: Animals; Apoptosis; Captopril; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelin-1; Fibrosis; Inflammation; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Receptors, Angiotensin; Tannins | 2017 |
Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril.
Topics: Acetylcysteine; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension; Light; Male; Melatonin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ventricular Remodeling | 2017 |
Nigella sativa extract is a potent therapeutic agent for renal inflammation, apoptosis, and oxidative stress in a rat model of unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Apoptosis; Captopril; Chemokine CCL2; Creatinine; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Malondialdehyde; Nigella sativa; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Urea; Ureteral Obstruction | 2018 |
Immunomodulatory properties of captopril, an ACE inhibitor, on LPS-induced lung inflammation and fibrosis as well as oxidative stress.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Biomarkers; Captopril; Cytokines; Fibrosis; Immunologic Factors; Lipopolysaccharides; Lung; Lung Injury; Male; Neutrophils; Oxidative Stress; Pneumonia; Rats; Rats, Wistar | 2019 |
Stevioside attenuates isoproterenol-induced mouse myocardial fibrosis through inhibition of the myocardial NF-κB/TGF-β1/Smad signaling pathway.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomyopathies; Cell Line; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Fibrosis; Gene Expression Regulation; Glucosides; Isoproterenol; Male; Mice; NF-kappa B; Smad Proteins; Transforming Growth Factor beta1 | 2019 |
ACE inhibitor reduces radiation injury to myocardium.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Fibrosis; Heart; Myocardium; Neoplasms; Pulmonary Fibrosis; Radiation Injuries; Radiation-Protective Agents; Rats | 2013 |
Enhanced survival from radiation pneumonitis by combined irradiation to the skin.
Topics: Animals; Captopril; Collagen; Female; Fibrosis; Lung; Radiation Injuries; Radiation Injuries, Experimental; Radiation Pneumonitis; Rats; Skin; Thorax; Time Factors; Treatment Outcome; Wound Healing; X-Rays | 2014 |
Qishenyiqi protects ligation-induced left ventricular remodeling by attenuating inflammation and fibrosis via STAT3 and NF-κB signaling pathway.
Topics: Angiotensin II; Animals; Captopril; Drugs, Chinese Herbal; Fibrosis; Heart Failure; Heart Ventricles; Hemodynamics; Inflammation; Interleukin-6; Ligation; Male; Matrix Metalloproteinases; NADPH Oxidases; NF-kappa B; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor; Ventricular Remodeling | 2014 |
Profibrosing effect of angiotensin converting enzyme inhibitors in human lung fibroblasts.
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Enalapril; Fibroblasts; Fibrosis; Fumarates; Humans; Losartan; Lung; Protein Biosynthesis; Renin; Transcription, Genetic; Transforming Growth Factor beta1 | 2015 |
N-Acetyl-seryl-aspartyl-lysyl-proline Alleviates Renal Fibrosis Induced by Unilateral Ureteric Obstruction in BALB/C Mice.
Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chemokine CCL2; Collagen Type IV; Fibrosis; Immunohistochemistry; Inflammation; Kidney Diseases; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; Oligopeptides; Real-Time Polymerase Chain Reaction; Ureteral Obstruction | 2015 |
Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy.
Topics: Acute Kidney Injury; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Blood Urea Nitrogen; Captopril; Cytochrome P450 Family 2; Cytoprotection; Eicosanoids; Fas Ligand Protein; fas Receptor; Fibrosis; Hypertension; Kidney; Male; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Renal Circulation; Signal Transduction; Steroid 16-alpha-Hydroxylase | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Hypertension; Male; Myocardium; Rats, Wistar; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2016 |
N-acetyl-seryl-aspartyl-lysyl-proline mediates the anti-fibrotic properties of captopril in unilateral ureteric obstructed BALB/C mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Indoles; Kidney; Kidney Diseases; Male; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Peptidyl-Dipeptidase A; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Signal Transduction; Thiazolidines; Transforming Growth Factor beta1; Ureteral Obstruction | 2018 |
Differential response of bone and kidney to ACEI in db/db mice: A potential effect of captopril on accelerating bone loss.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Bone and Bones; Bone Resorption; Calcium; Captopril; Diabetes Mellitus, Experimental; Femur; Fibrosis; Kidney; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Renin-Angiotensin System; RNA, Messenger; Tibia; Vitamin D3 24-Hydroxylase; X-Ray Microtomography | 2017 |
Effect of captopril on radiation-induced TGF-β1 secretion in EA.Hy926 human umbilical vein endothelial cells.
Topics: A549 Cells; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blotting, Western; Captopril; Cells, Cultured; Fibrosis; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; NF-kappa B; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; X-Rays | 2017 |
Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Disease Models, Animal; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Wistar; Ventricular Dysfunction, Right | 2008 |
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carbocyanines; Cardiovascular Agents; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Fibrillar Collagens; Fibroblasts; Fibrosis; Losartan; Mice; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; Oligopeptides; Predictive Value of Tests; Spironolactone; Technetium; Tomography, Emission-Computed, Single-Photon; Ventricular Function, Left; Ventricular Remodeling | 2009 |
Catecholamine-induced myocardial fibrosis and oxidative stress is attenuated by Terminalia arjuna (Roxb.).
Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Captopril; Cardiomegaly; Fibrosis; Heart; Isoproterenol; Male; Myocardium; Organ Size; Oxidative Stress; Peptidyl-Dipeptidase A; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Rats; Rats, Wistar; Terminalia | 2009 |
ADAMTS-1 contributes to the antifibrotic effect of captopril by accelerating the degradation of type I collagen in chronic viral myocarditis.
Topics: ADAM Proteins; ADAMTS1 Protein; Animals; Blotting, Western; Captopril; Chronic Disease; Collagen Type I; Coloring Agents; Fibrinolysis; Fibrosis; Kinetics; Male; Mice; Mice, Inbred BALB C; Myocarditis; Peptide Fragments; Peptides; Procollagen; Reverse Transcriptase Polymerase Chain Reaction; Staining and Labeling | 2010 |
[Antifibrotic effects of oxymatrine in mice with chronic viral myocarditis].
Topics: Alkaloids; Animals; Antiviral Agents; Captopril; Chronic Disease; Disease Models, Animal; Down-Regulation; Enterovirus B, Human; Fibrosis; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Quinolizines; Transforming Growth Factor beta1; Virus Diseases | 2010 |
Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats.
Topics: Animals; Benzimidazoles; Benzoates; Captopril; Drug Therapy, Combination; Fibrosis; Gene Expression Regulation, Enzymologic; Isoproterenol; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Random Allocation; Rats; Rats, Wistar; Telmisartan; Ventricular Dysfunction, Left | 2010 |
The effect of indapamide on development of myocardial hypertrophy and fibrosis in L-NAME-induced hypertension in rat.
Topics: Animals; Captopril; Collagen Type I; Collagen Type III; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar | 2011 |
Endogenous aldosterone is involved in vascular calcification in rat.
Topics: Aldosterone; Alkaline Phosphatase; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; Captopril; Cholecalciferol; Collagen; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Nicotine; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone; Vascular Calcification | 2012 |
Angiotensin converting enzyme inhibitors mitigate collagen synthesis induced by a single dose of radiation to the whole thorax.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Collagen; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Enalapril; Female; Fibrosis; Fosinopril; Gene Expression Regulation; Lung; Pulmonary Fibrosis; Radiation Pneumonitis; Rats; Renin-Angiotensin System; Thorax | 2012 |
Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Bone Morphogenetic Protein Receptors; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Protein Receptors, Type II; Bone Morphogenetic Proteins; Captopril; Diabetic Nephropathies; Epithelial-Mesenchymal Transition; Fibrosis; Inflammation; Kidney; Kidney Tubules; Mice; Peptide Library; Peptides; Rats; Rats, Sprague-Dawley; Regeneration; Signal Transduction; Smad3 Protein; Structure-Activity Relationship; Transforming Growth Factor beta | 2012 |
Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats.
Topics: Acute Kidney Injury; Animals; Antibodies, Anti-Idiotypic; Antihypertensive Agents; Blood Pressure; Captopril; Diltiazem; Disease Models, Animal; Female; Fibrosis; Hydrochlorothiazide; Hypertension; Male; Proteinuria; Rats; Rats, Inbred Dahl; Sex Characteristics; Sodium Chloride, Dietary; Transforming Growth Factor beta | 2012 |
Antifibrotic role of captopril after ureteral injury.
Topics: Animals; Captopril; Fibrosis; Male; Rabbits; Ureter | 2012 |
Captopril ameliorates myocarditis in acute experimental Chagas disease.
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Protozoan; Captopril; Chagas Cardiomyopathy; Dose-Response Relationship, Drug; Fibrosis; Hypersensitivity, Delayed; Male; Mice; Necrosis; Parasitemia; Survival Analysis; Trypanosoma cruzi | 2003 |
Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure.
Topics: Administration, Oral; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Captopril; Diuresis; Drug Therapy, Combination; Fibrosis; Heart Failure; Heart Ventricles; Hypertension; Hypertrophy; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Spironolactone; Time Factors; Ultrasonography | 2003 |
Renal effects of omapatrilat and captopril in salt-loaded, nitric oxide-deficient rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blood Vessels; Captopril; Cyclic GMP; Endothelin-1; Enzyme Inhibitors; Fibrosis; Hypertension, Renal; Kidney; Male; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protease Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride; Survival Rate; Thiazepines | 2003 |
Comparative effects of a vasopeptidase inhibitor vs. an angiotensin converting enzyme inhibitor on cardiomyocyte apoptosis in rats with heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Cells, Cultured; DNA; Electrophoresis, Agar Gel; Enzyme Inhibitors; Fibrosis; Heart Failure; Hemodynamics; Hydrogen Peroxide; Inhibitory Concentration 50; Male; Myocytes, Cardiac; Protease Inhibitors; Pyridines; Rats; Rats, Wistar; Thiazepines; Time Factors | 2003 |
Antifibrotic effect of Ac-SDKP and angiotensin-converting enzyme inhibition in hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cell Division; Collagen; Connective Tissue Growth Factor; Drug Therapy, Combination; Fibrosis; Growth Inhibitors; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Macrophages; Male; Mast Cells; Monocytes; Myocardium; Myocytes, Cardiac; Oligopeptides; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2004 |
Contribution of angiotensin II to alcohol-induced pancreatic fibrosis in rats.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Captopril; Central Nervous System Depressants; Collagen; Cytokines; Ethanol; Fibrosis; Immunohistochemistry; Losartan; Male; Pancreas; Pancreatic Diseases; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Ribonucleases; RNA, Messenger | 2004 |
Prevention of fibrosis in experimental colitis by captopril: the role of tgf-beta1.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colitis; Colon; Disease Models, Animal; Fibrosis; Male; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Inhibition of both neutral endopeptidase and endothelin-converting enzyme by SLV306 reduces proteinuria and urinary albumin excretion in diabetic rats.
Topics: Administration, Oral; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Benzazepines; Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelin-Converting Enzymes; Fibrosis; Kidney; Metalloendopeptidases; Neprilysin; Protease Inhibitors; Proteinuria; Rats; Rats, Wistar; Time Factors | 2004 |
Connective tissue growth factor and cardiac fibrosis after myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Collagen Type I; Connective Tissue Growth Factor; Fibrosis; Immediate-Early Proteins; Immunohistochemistry; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Rats; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling | 2005 |
Effects of salt loading and various therapies on cardiac hypertrophy and fibrosis in young spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Cardiomegaly; Collagen; Eating; Fibrosis; Hemodynamics; Lung; Male; Myocardium; Nuclease Protection Assays; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA; Sodium Chloride; Verapamil | 2006 |
Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Captopril; Disease Models, Animal; Enzyme Activation; Fibrosis; Heart; Hypertension; Inflammation; Kidney; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Rats | 2007 |
Captopril reduces interstitial renal fibrosis and preserves more normal renal tubules in neonatal dogs with partial urethral obstruction: a preliminary study.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Captopril; Dogs; Fibrosis; Kidney; Kidney Tubules; Urethral Obstruction | 2007 |
[Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats].
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Bile Ducts; Captopril; Fibrosis; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Losartan; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2007 |
Comparison of the effects of captopril, tamoxifen and L-carnitine on renal structure and fibrosis after total unilateral ureteral obstruction in the rat.
Topics: Animals; Captopril; Carnitine; Female; Fibrosis; Kidney; Rats; Rats, Sprague-Dawley; Tamoxifen; Ureteral Obstruction | 2007 |
Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates ACE and AT1 receptor gene expression and signaling: role in cardiac hypertrophy.
Topics: Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic GMP; Fibrosis; Gene Expression Regulation; Guanylate Cyclase; Heart Ventricles; Hydralazine; Hypertension; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Renin-Angiotensin System; Signal Transduction; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2007 |
Comparison of angiotensin converting enzyme inhibition and angiotensin II receptor blockade for the prevention of experimental autoimmune myocarditis.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoantibodies; Autoimmunity; Captopril; Fibrosis; Losartan; Male; Mice; Myocarditis; Myosins | 2008 |
Effect of captopril on changes in rats' hearts induced by long-term irradiation.
Topics: Animals; Captopril; Cobalt Radioisotopes; Female; Fibrosis; Gamma Rays; Heart Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Wistar; Time Factors | 1993 |
Captopril prevents vascular and fibrotic changes but not cardiac hypertrophy in aortic-banded rats.
Topics: Animals; Aorta; Blood Pressure; Captopril; Cardiomegaly; Constriction; Coronary Circulation; Coronary Vessels; Fibrosis; In Vitro Techniques; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1996 |
Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cytokines; Enalapril; Fibrin; Fibrinolysin; Fibrosis; Gene Expression Regulation, Enzymologic; Growth Substances; Imidazoles; In Situ Hybridization; Kidney; Male; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; RNA, Messenger; Tetrazoles; Thrombosis; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator; Vasoconstrictor Agents | 1997 |
Effects of captopril on interstitial collagen in the myocardium after infarction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Fibrosis; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar | 1997 |
Human lung myofibroblast-derived inducers of alveolar epithelial apoptosis identified as angiotensin peptides.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Antibodies; Apoptosis; Blotting, Western; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Flow Cytometry; Gene Expression; Humans; Peptidyl-Dipeptidase A; Pulmonary Alveoli; Saralasin | 1999 |
Age-related progressive renal fibrosis in rats and its prevention with ACE inhibitors and taurine.
Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Extracellular Matrix Proteins; Fibrosis; Kidney Cortex; Kidney Diseases; Lisinopril; Male; Rats; Rats, Inbred F344; RNA, Messenger; Taurine; Transforming Growth Factor beta | 2000 |
Regression of myocardial fibrosis in hypertensive heart disease: diverse effects of various antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Captopril; Collagen; Fibrosis; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Labetalol; Male; Myocardium; Nifedipine; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2000 |
Angiotensin II-induced cardiomyocyte hypertrophy and cardiac fibrosis in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Collagen; Fibrosis; Heart; Heart Ventricles; Hemodynamics; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Myosin Heavy Chains; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tetrazoles | 2000 |
Reversal of cardiac hypertrophy and fibrosis by S21402, a dual inhibitor of neutral endopeptidase and angiotensin converting enzyme in SHRs.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiomegaly; Enzyme Inhibitors; Fibrosis; Hypertension; Kidney; Male; Methionine; Myocardium; Neprilysin; Organ Size; Propionates; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin; Sulfhydryl Compounds | 2000 |
Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bone Marrow Transplantation; Captopril; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Fibrosis; Imidazoles; Kidney Diseases; Male; Radiotherapy; Rats; Tetrazoles; Time Factors | 2001 |
Evidence for modulation of pericryptal sheath myofibroblasts in rat descending colon by transforming growth factor beta and angiotensin II.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Collagen; Colon; Diet, Sodium-Restricted; Fibroblasts; Fibrosis; Male; Radiation Injuries; Rats; Rats, Wistar; Receptors, Transforming Growth Factor beta; Sodium, Dietary; Transforming Growth Factor beta | 2002 |
Cardiac myocyte necrosis induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Captopril; Cardiomegaly; DNA; Fibrosis; Heart; Ligation; Male; Myocardium; Necrosis; Rats; Rats, Inbred Strains; Sympatholytics; Vasoconstriction | 1991 |
Coronary vascular remodeling and myocardial fibrosis in the rat with renovascular hypertension. Response to captopril.
Topics: Administration, Oral; Animals; Captopril; Cardiomyopathies; Coronary Circulation; Fibrosis; Hemodynamics; Hypertension, Renovascular; Kidney; Male; Rats; Rats, Inbred Strains | 1991 |
Role of renin-angiotensin system in the pathogenesis of spontaneous myocardial fibrosis in Sprague-Dawley rats: effect of long-term administration of captopril.
Topics: Animals; Body Weight; Captopril; Cardiomyopathies; Drinking; Eating; Female; Fibrosis; Kidney; Male; Myocardium; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Time Factors | 1989 |
Renal nerves mediate blunted natriuresis to atrial natriuretic peptide in cirrhotic rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Captopril; Denervation; Fibrosis; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Nervous System; Rats; Rats, Inbred Strains; Renal Circulation | 1987 |