Compounds > captopril
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captopril and Fibrosis, Radiation

captopril has been researched along with Fibrosis, Radiation in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fish, BL; Gao, F; Jacobs, ER; Lazarova, Z; Medhora, M; Moulder, JE; Narayanan, J; Schock, A; Szabo, A1
Doctrow, SR; Hill, RP; Jelveh, S; Mahmood, J; Medhora, M; Zaidi, A1
Berk, LB; Fintel, DJ; Garces, YI; Ivker, R; James, JL; Lutz, ST; Moore, TD; Moulder, J; Movsas, B; Pugh, S; Small, W; Suntharalingam, M1
Fish, BL; Ghosh, SN; Jacobs, ER; Li, XA; Medhora, M; Moulder, JE; Semenenko, VA; Zhang, R1
Cohen, EP; Gore, E; Kharofa, J; Tomic, R; Xiang, Q1
Fish, BL; Gao, F; Jacobs, ER; Kma, L; Medhora, M; Moulder, JE1
Fish, BL; Gao, F; Jacobs, ER; Medhora, M; Moulder, JE; Szabo, A1
Fish, BL; Jacobs, ER; Medhora, MM; Molthen, RC; Moulder, JE; Wu, Q1
Diz, DI; Robbins, ME1

Reviews

1 review(s) available for captopril and Fibrosis, Radiation

ArticleYear
Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects.
    International journal of radiation oncology, biology, physics, 2006, Jan-01, Volume: 64, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Brain; Captopril; Humans; Inflammation; Kidney; Lung; NADP; Neoplasms; Oxidative Stress; Radiation Injuries; Radiation Pneumonitis; Reactive Oxygen Species; Renin-Angiotensin System; Survivors

2006

Trials

1 trial(s) available for captopril and Fibrosis, Radiation

ArticleYear
Utility of the ACE Inhibitor Captopril in Mitigating Radiation-associated Pulmonary Toxicity in Lung Cancer: Results From NRG Oncology RTOG 0123.
    American journal of clinical oncology, 2018, Volume: 41, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carcinoma, Non-Small-Cell Lung; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Quality of Life; Radiation Injuries; Radiation Pneumonitis; Radiotherapy, Conformal

2018

Other Studies

7 other study(ies) available for captopril and Fibrosis, Radiation

ArticleYear
Enhanced survival from radiation pneumonitis by combined irradiation to the skin.
    International journal of radiation biology, 2014, Volume: 90, Issue:9

    Topics: Animals; Captopril; Collagen; Female; Fibrosis; Lung; Radiation Injuries; Radiation Injuries, Experimental; Radiation Pneumonitis; Rats; Skin; Thorax; Time Factors; Treatment Outcome; Wound Healing; X-Rays

2014
Targeting the Renin-angiotensin system combined with an antioxidant is highly effective in mitigating radiation-induced lung damage.
    International journal of radiation oncology, biology, physics, 2014, Jul-15, Volume: 89, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Captopril; Deoxyguanosine; DNA Damage; Drug Therapy, Combination; Female; Lipid Peroxidation; Lung; Organometallic Compounds; Radiation Injuries, Experimental; Radiation Pneumonitis; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Respiratory Rate; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1

2014
Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis.
    International journal of radiation oncology, biology, physics, 2009, Dec-01, Volume: 75, Issue:5

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Evaluation, Preclinical; Female; Losartan; Lung; Pulmonary Artery; Radiation Dosage; Radiation Injuries, Experimental; Radiation Pneumonitis; Rats; Renin-Angiotensin System; Respiratory Mechanics; Time Factors; Vasoconstriction; Vasodilation

2009
Decreased risk of radiation pneumonitis with incidental concurrent use of angiotensin-converting enzyme inhibitors and thoracic radiation therapy.
    International journal of radiation oncology, biology, physics, 2012, Sep-01, Volume: 84, Issue:1

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carcinoma, Non-Small-Cell Lung; Humans; Incidence; Lisinopril; Lung; Lung Neoplasms; Male; Middle Aged; Radiation Pneumonitis; Retrospective Studies; Small Cell Lung Carcinoma; Tumor Burden

2012
Angiotensin converting enzyme inhibitors mitigate collagen synthesis induced by a single dose of radiation to the whole thorax.
    Journal of radiation research, 2012, Volume: 53, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Collagen; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Enalapril; Female; Fibrosis; Fosinopril; Gene Expression Regulation; Lung; Pulmonary Fibrosis; Radiation Pneumonitis; Rats; Renin-Angiotensin System; Thorax

2012
Dose-modifying factor for captopril for mitigation of radiation injury to normal lung.
    Journal of radiation research, 2012, Volume: 53, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Radiation; Female; Humans; Lung; Lung Injury; Proportional Hazards Models; Radiation Injuries; Radiation Pneumonitis; Rats; Rats, Wistar; Respiration; Tachypnea; Time Factors

2012
Mitigation of radiation induced pulmonary vascular injury by delayed treatment with captopril.
    Respirology (Carlton, Vic.), 2012, Volume: 17, Issue:8

    Topics: Acute Lung Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Lung; Radiation Dosage; Radiation Injuries; Radiation Pneumonitis; Rats; Thorax; Vascular System Injuries

2012