captopril has been researched along with Disease Models, Animal in 305 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (8.20) | 18.7374 |
| 1990's | 74 (24.26) | 18.2507 |
| 2000's | 106 (34.75) | 29.6817 |
| 2010's | 80 (26.23) | 24.3611 |
| 2020's | 20 (6.56) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Allagnat, F; Corpataux, JM; Déglise, S; Deslarzes-Dubuis, C; Lambelet, M; Longchamp, A; Macabrey, D; Ozaki, CK | 1 |
| Chen, K; Gao, X; Hu, C; Jiang, Z; Liu, K | 1 |
| Beurskens, S; Dijkman, H; Roelofs, R; Smeets, B; Swinkels, DW; Thévenod, F; van der Vlag, J; van Swelm, RPL; Wetzels, JFM; Wiegerinck, ETG | 1 |
| Kasono, K; Kitamori, K; Kobayashi, J; Kono, Y; Ohtake, K; Shiba, S; Sonoda, K | 1 |
| Adeyemi, O; Afolayan, O; Badru, A; Ishola, I; John, N; Olubodun-Obadun, T | 1 |
| Fang, ZQ; Huo, YL; Johnson, AK; Li, JD; Peng, W; Wang, HP; Wang, XF; Xue, B; Zhang, YP | 1 |
| Adedapo, AA; Adedapo, ADA; Ajayi, AM; Ekwunife, NL; Falayi, OO; Omobowale, TO; Oyagbemi, A | 1 |
| Christophi, C; Fifis, T; Kastrappis, G; Paolini, R; Perini, MV; Vallejo Ardila, DL; Walsh, KA | 1 |
| Andrade, CAF; Andrade-Franzé, GMF; De Luca, LA; Menani, JV; Pereira, ED; Samson, WK; Yosten, GLC | 1 |
| Ade, CJ; Baumfalk, DR; Butenas, ALE; Colburn, TD; Copp, SW; Hageman, KS; Musch, TI; Poole, DC | 1 |
| Kim, JH; Kim, JW; Rha, EY; Yoo, G | 1 |
| Brusco, I; Justino, AB; Machado-de-Ávila, RA; Oliveira, SM; Scussel, R; Silva, CR | 1 |
| Christie, RM; Hansen, HH; Hecksher-Sørensen, J; Jelsing, J; MacKrell, JG; Pedersen, PJ; Rolin, B; Roostalu, U; Salinas, CG; Skytte, JL; Thisted, L; Vrang, N; Zois, NE | 1 |
| Bovée, DM; Clahsen-van Groningen, MC; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Lu, X; Melton, L; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Akbar Nekooeian, A; Dehghani, F; Esmaeilpour, T; Mashghoolozekr, E; Rasti Pour, A | 1 |
| Brem, H; Casaos, J; Huq, S; Mangraviti, A; Paldor, I; Perdomo-Pantoja, A; Pinheiro, L; Tyler, B; Vigilar, V; Wang, Y; Witham, TF | 1 |
| Bouten, RM; Bylicky, MA; Day, RM; Di Pucchio, T; Du, Y; Gudmundsson, KO; Lee, SH; McCart, EA; Muir, JM; Mungunsukh, O; Olsen, CH; Rittase, WB; Slaven, JE; Wilkins, WL | 1 |
| Chu, L; Han, X; Li, P; Liu, T; Song, Q; Song, T; Zhang, J; Zhang, X; Zhang, Y | 1 |
| Krzemiński, TF; Mitręga, KA; Nożyński, J; Porc, M; Spałek, AM; Stankiewicz, M | 1 |
| Cai, W; Qiu, L; Sun, H; Zhang, Q; Zhou, Y; Zhou, Z; Zhu, X | 1 |
| Adamcova, M; Aziriova, S; Balazova, L; Celec, P; Krajcirovicova, K; Pechanova, O; Repova, K; Simko, F; Tothova, L; Vrankova, S; Zorad, S | 1 |
| Daneshtalab, N; Smeda, JS | 1 |
| Aliev, OI; Anishchenko, AM; Arkhipov, AM; Plotnikov, MB; Shamanaev, AY; Sidekhmenova, AV | 1 |
| Akershoek, JJJ; Beelen, RHJ; Boekema, BKHL; Brouwer, KM; Middelkoop, E; Ulrich, MMW; Vlig, M | 1 |
| Bobadilla Lugo, RA; Bracho Valdes, I; Rosas, P; Tufiño, C | 1 |
| Alimoradian, A; Changizi-Ashtiyani, S; Ghiasabadi Farahani, A; Kheder, L; Rajabi, R; Sharifi, A | 1 |
| Arellano-Mendoza, MG; Del Valle-Mondragón, L; Guevara-Salazar, JA; Montes-Rivera, JO; Quintana-Pérez, JC; Tamay-Cach, F; Trujillo-Ferrara, JG | 1 |
| An, L; Li, CS; Liu, QT; Tong, N; Xiao, HL; Xie, MR; Yang, J; Zhao, LX | 2 |
| El-Ashmawy, NE; El-Bahrawy, HA; Hamada, OB; Khedr, NF | 1 |
| Bastacky, SI; Jackson, EK; Salah, EM; Tofovic, SP | 1 |
| Al-Mashhadi, A; Carlström, M; Dimke, H; Jensen, BL; Svenningsen, P; Zachar, R | 1 |
| Dong, LY; Jin, KK; Qiu, XX; Yao, LP; Zhao, J | 1 |
| Negandhi, A; Smeda, JS; Stuckless, J; Watson, D | 1 |
| Abreu, TP; Caruso-Neves, C; Dal-Cheri, BKA; Henriques, MG; Peruchetti, DB; Pinheiro, AAS; Silva, LS; Silva-Aguiar, RP; Souza, MC; Takiya, CM | 1 |
| Chen, F; Chen, J; Chen, W; Han, L; Jia, L; Li, F; Lin, M; Shao, JW; Wang, C; Wang, J; Zhou, Y | 1 |
| Flores-Monroy, J; Fonseca-Coronado, S; Hernandez-Campos, ME; Lezama-Martinez, D; Martinez-Aguilar, L; Valencia-Hernandez, I | 1 |
| Aquino, V; Colon-Perez, L; Febo, M; Goel, R; Li, H; Lobaton, GO; Pepine, CJ; Qi, Y; Raizada, MK; Richards, EM; Yang, T; Zubcevic, J | 1 |
| Day, RM; Jha, J; Lee, YH; McCart, EA; Muir, J; Mungunsukh, O; Rittase, WB; Summers, TA | 1 |
| Agarwal, R; Azis, NA; Ismail, NH; Ismail, NM; Kamal, MSA; Radjeni, Z; Singh, HJ | 1 |
| Beltz, TG; Felder, RB; Guo, F; Johnson, AK; Wei, SG; Xue, B; Yu, Y | 1 |
| Chen, L; Hou, I; Zhang, X | 1 |
| Alcaide-Hidalgo, JM; Bravo, FI; López-Huertas, E; Margalef, M; Muguerza, B | 1 |
| Gao, X; Li, S; Wang, R; Wei, Z; Xu, D; Xu, H; Yang, F; Yi, X; Zhang, B; Zhang, G; Zhang, H; Zhang, L; Zhang, X; Zhang, Y; Zhu, Y | 1 |
| Demiralay, E; Ozdamar, EN; Saglam, E; Saglam, IY; Sehirli, AO; Sener, G | 2 |
| Ager, EI; Christophi, C; Neo, J; Wen, SW | 1 |
| Arsenault, M; Couet, J; Dhahri, W; Drolet, MC; Gascon, S; Grenier, A; Lecomte, R; Rousseau, JA; Roussel, E; Sarrhini, O; Zendaoui, A | 1 |
| AbdAlla, S; Fu, X; Langer, A; Quitterer, U | 1 |
| Mei, X; Wang, J; Zhang, Q; Zhang, X | 1 |
| Bult, H; Herijgers, P; Mubagwa, K; Nevelsteen, I; Van den Bergh, A; Van der Mieren, G; Vanderper, A | 1 |
| Abdusalam, E; Abliz, P; Aji, Q; Iskandar, G; Issak, M; Moore, N; Reyim, N; Tian, S; Umar, A; Zhou, W | 1 |
| Ackerman, Z; Grozovski, M; Oron-Herman, M; Sela, BA; Skarzinski, G | 1 |
| Cenksoy, C; Dursun, P; Erdem, O; Guner, H; Karabacak, O; Karakaya, C; Oktem, M; Ozcan, P | 1 |
| Ferrario, CM; Flores-Monroy, J; Hernández-Campos, ME; Martínez-Aguilar, L; Valencia-Hernández, I | 1 |
| Beltz, TG; Hurley, SW; Johnson, AK; Xue, B; Zhang, Z | 1 |
| Bai, X; Chai, R; Guo, W; Han, Y; Li, J; Wang, H; Xu, L; Yan, W | 1 |
| Abdollahifar, MA; Jahanabadi, Z; Noorafshan, A; Shirazi, M; Soltani, MR; Tanideh, N | 1 |
| de Figueiredo, SG; Gava, PL; Guimarães, MC; Mauad, H; Pereira, FE; Waichert, ÉJ; Wittmer, VL | 1 |
| Bencsik, P; Cabrera-Fuentes, HA; Csonka, C; Ferdinandy, P; Preissner, KT; Sárközy, M; Schlüter, KD; Schreckenberg, R; Schulz, R; Steinert, I; Weber, P | 1 |
| Araújo, WF; Naves, MA; Ravanini, JN; Schor, N; Teixeira, VP | 1 |
| Grabowska, EM; Pillidge, K; Porter, AJ; Stanford, SC | 1 |
| Del Valle-Mondragón, L; Guzmán-Hernández, EA; Ibarra-Barajas, M; Pastelín-Hernández, G; Sánchez-Mendoza, MA; Villalobos-Molina, R | 1 |
| Ding, Z; Ge, J; Gong, H; Jiang, G; Li, Y; Wang, S; Wang, X; Wu, J; Ye, Y; Yin, P; Yuan, J; Zhang, W; Zhou, J; Zou, Y | 1 |
| Blain, A; Blamire, AM; Greally, E; Laval, SH; MacGowan, GA; Straub, VW | 1 |
| Chen, L; Chen, P; Hu, LQ; Li, HQ; Li, TT; Rong, R; Tang, J; Yin, CS; Zhang, Q | 1 |
| Johnson, AK; Thunhorst, RL; Xu, J | 1 |
| Chen, CX; Gao, JP; Gu, WL; Huang, XY | 1 |
| Deussen, A; Henle, T; Jannasch, A; Kopaliani, I; Martin, M; Mund, C; Todorov, V | 1 |
| Issakainen, T; Korpela, R; Salmenkari, H; Vapaatalo, H | 1 |
| Flores-Monroy, J; González-Espinosa, C; Lezama-Martínez, D; Martínez-Aguilar, L; Orozco-Cortés, NV; Valencia-Hernández, I | 1 |
| Hongyuan, B; Jingwen, Z; Li, G; Xin, D; Yajuan, N | 1 |
| Bunbupha, S; Kukongviriyapan, U; Kukongviriyapan, V; Maneesai, P; Pakdeechote, P; Prachaney, P; Prasarttong, P; Tangsucharit, P | 1 |
| Guan, JX; Lu, ZN; Zeng, YP; Zhou, Q; Zhou, Y | 1 |
| An, L; Li, CS; Liu, QT; Tong, N; Xiao, HL; Yang, J; Zhao, LX | 1 |
| Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA | 1 |
| Chan, GCW; Chan, KW; Huang, XR; Lai, KN; Lan, HY; Tang, SCW; Wu, HJ; Yiu, WH; Zou, A | 1 |
| Ang, CY; Korzh, V; Li, M; Li, P; Tan, SY; Teh, C; Zhao, Y | 1 |
| Dobešová, Z; Kunes, J; Zicha, J | 1 |
| Abd-Ellah, MF; Attia, SM; El-Sayed, el-SM | 1 |
| Aneja, R; Katyal, A; Kumar, M; Kumaran, D; Udayabanu, M | 1 |
| Blantz, RC; Deng, A; Satriano, J; Singh, P; Tang, T; Thomson, SC; Wang, C | 1 |
| Byku, M; Macarthur, H; Westfall, TC | 1 |
| Dimitrijevic, J; Djukanovic, L; Jovanovic, D; Jovovic, D; Maksic, N; Mihailovic-Stanojevic, N; Miloradovic, Z; Naumovic, R | 1 |
| Hara, Y; Harada, T; Hori, Y; Kikuzuki, R; Okada, M; Yamawaki, H | 1 |
| Arsenault, M; Beaudoin, J; Bojmehrani, A; Champetier, S; Couet, J; Lachance, D; Plante, E; Roussel, E | 1 |
| Lee, DH; Leong, PK; Maunsbach, AB; McDonough, AA; Riquier, AD; Yang, LE | 1 |
| Araujo, IG; Costa-E-Sousa, RH; Mecawi, AS; Olivares, EL; Reis, LC; Sonoda-Côrtes, R; Trindade, DC; Werneck-de-Castro, JP | 1 |
| Bahri, MA; Hassanpoor, A; Noorafshan, A; Shirazi, M | 1 |
| Bauer, R; Blain, A; Bushby, K; MacGowan, GA; Straub, V | 1 |
| Blankesteijn, WM; Daemen, MJ; Fujimoto, A; Fujimoto, S; Hofstra, L; Isobe, S; Li, P; Lovhaug, D; Narula, J; Narula, N; Petrov, A; Pitt, B; Reutelingsperger, C; Smits, JF; van den Borne, SW; Vannan, MA; Wong, ND; Zandbergen, HR; Zannad, F | 1 |
| Kasai, T; Shimizu, F; Takamata, A | 1 |
| Lacombe, MJ; Mercure, C; Prescott, G; Reudelhuber, TL; Silversides, DW | 1 |
| Dai, YL; Su, D; Wu, DZ; Yan, HR; Zhang, BB | 1 |
| Celik, HA; Ilter, T; Nart, D; Oruc, N; Ozutemiz, O; Yuce, G | 1 |
| Darrow, AL; Leo, GC | 1 |
| Flora, SJ; Mehta, A; Mishra, D; Pachauri, V; Saxena, G | 1 |
| Johnson, RJ; Mu, W; Nakagawa, T; Reungjui, S; Roncal, CA; Sánchez-Lozada, LG; Sautin, YY | 1 |
| Campos, RR; Carillo, BA; Couto, GK; Prezoto, BC; Rossoni, LV; Schoorlemmer, GH | 1 |
| Arsenault, M; Beaudoin, J; Champetier, S; Couet, J; Lachance, D; Plante, E; Roussel, E | 1 |
| Cho, YK; Choi, WY; Eom, GH; Kee, HJ; Kim, HS; Kook, H; Ma, JS; Nam, KI | 1 |
| Berké, B; Imam, G; Kerim, P; Moore, N; Tohti, I; Umar, A; Yimin, W | 1 |
| Harford-Wright, E; Thornton, E; Vink, R | 1 |
| Bouhuizen, AM; Danser, AH; Garrelds, IM; Leijten, F; Moltzer, E; van Esch, JH; van Veghel, R | 1 |
| Chen, Y; Fang, YN; Guo, CY; Li, Q; Wang, Y | 1 |
| Kang, HS; Kim, JS; Kim, SJ; Kim, SZ; Lee, YU; Rahman, M | 1 |
| Adler, F; Herndon, B; Lankachandra, K; McIff, TE; Molteni, A; Poisner, AM | 1 |
| Czuczwar, SJ; Jakubus, T; Lukawski, K; Raszewski, G | 1 |
| Constancio, J; de Almeida, RL; De Luca, LA; Fracasso, JF; Menani, JV; Vendramini, RC | 1 |
| Jouyban, A; Karimi, I; Saghaei, F; Samini, M | 1 |
| Liu, X; Wu, Y | 1 |
| Chen, X; Ji, ZZ; Li, SL; Wu, T; Zhang, XW | 1 |
| Chen, JB; Huang, CX; Sun, XM | 1 |
| Cohen, EP; Fish, BL; Klein, JP; Moulder, JE | 1 |
| Bean, JS; Kassab, GS; Lu, X; Rekhter, MD | 1 |
| Gopcevic, K; Kojic, Z; Marinkovic, D; Tasic, G | 1 |
| Acar, A; Alp, H; Evliyaoğlu, O; Fırat, U; Göçmez, C; Ilhan, A; Kamasak, K; Taşdemir, N; Tüfek, A; Uzar, E | 1 |
| Chen, CC; Dahly-Vernon, AJ; Dunn, KM; Ledbetter, SR; Murphy, SR; Roman, RJ; Williams, JM | 1 |
| Akhtar, S; Benter, IF; Dhaunsi, GS; Makki, BM; Qabazard, BA; Yousif, MH | 1 |
| Liang, J; Su, Q; Sun, W; Yu, J; Zhang, Y; Zhao, L; Zhao, W | 1 |
| Dickinson, BA; Hullinger, TG; Latimer, PA; Lewton, SM; Lynch, JM; Montgomery, RL; Semus, HM; Seto, AG; Stack, C; van Rooij, E | 1 |
| Bahl, JJ; Goldman, S; Morkin, E; Pennock, GD; Spooner, PH | 1 |
| Bregonzio, C; Falcón-Neri, A; Ito, T; Saavedra, JM; Terrón, JA; Yamakawa, H | 1 |
| Liu, H; Zhao, J | 1 |
| Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R | 1 |
| Delbridge, L; Griffiths, C; Morgan, T | 1 |
| Djordjevic, V; Jevtovic, T; Kocic, G; Kocic, R; Pavlovic, D; Vlahovic, P | 1 |
| Qui, XS; Sim, MK | 1 |
| Brzoska, T; Luger, TA; Riemann, H; Scholzen, TE; Ständer, S | 1 |
| Browne, AE; Chatterjee, K; Grossman, W; Karliner, JS; Lee, RJ; Parmley, WW; Sievers, RE; Zhu, BQ | 1 |
| Prado, CM; Ramos, SG; Rossi, MA | 1 |
| Bryant, JL; Davis, HG; Denaro, F; Jones, OD; Liu, XH; Owens, JW; Ray, PE; Reid, W; Robinson, LR; Xu, L | 1 |
| Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH | 1 |
| Gambino, A; Tsui, DY; Wanstall, JC | 1 |
| Johnsson, C; Lindström, P; Ollerstam, A; Persson, AE; Wadström, J | 1 |
| Kadish, I; van Groen, T; Wyss, JM | 1 |
| Bayram, I; Ozbek, H; Tuncer, I; Ugras, S | 1 |
| Barr, SM; Geng, Y; Higgins, RD; Sharma, J; Yan, Y | 1 |
| Goens, MB; Kanagy, NL; Lund, AK; Walker, MK | 1 |
| Mirelman, D; Miron, T; Peleg, E; Rabinkov, A; Rosenthal, T; Wilchek, M | 1 |
| Jeppsson, B; Menger, MD; Riaz, AA; Sato, T; Schramm, R; Thorlacius, H; Wang, Y | 1 |
| Arsenault, M; Couet, J; Drolet, MC; Gaudreau, M; Gauthier, C; Lachance, D; Lapointe, E; Plante, E; Roussel, E | 1 |
| Jochem, J | 1 |
| Iakubov, AV; Usmanova, ShE | 1 |
| Backer, CL; Crawford, SE; Huang, L; Huang, X; Mavroudis, C; Mu, Y; Pahl, E; Stellmach, V; Volpert, OV | 1 |
| Faitelson, Y; Goldin, E; Latella, G; Pappo, O; Pines, M; Sestieri, M; Villanova, A; Wengrower, D; Zannineli, G; Zanninelli, G | 1 |
| Hosseinimehr, SJ; Karami, M | 1 |
| Alican, I; Ercan, F; Gedik, N; Jahovic, N; Sener, G; Yüksel, M | 1 |
| Dimitrijevic, J; Djukanovic, L; Jovanovic, D; Jovovic, D; Maksic, N; Mihailovic-Stanojevic, N; Miloradovic, Z | 1 |
| DI, J; Huang, ST; Lei, XY; Li, JM; Lu, YS | 1 |
| Gao, XY; Wang, HJ; Wang, W; Zhang, F; Zhang, Y; Zhu, GQ | 1 |
| Tian, Y; Wang, J; Yu, LJ; Zhou, YZ; Zhu, SJ | 1 |
| Burssens, P; De Paepe, Y; Depaepe, Y; Forsyth, R; Steyaert, A; van Ovost, EJ; Verdonk, R | 1 |
| August, M; Baldus, S; Daiber, A; Fleming, I; Hink, U; Kleschyov, AL; Materne, A; Mollnau, H; Münzel, T; Nickenig, G; Oelze, M; Schulz, E; Wendt, M; Wenzel, P | 1 |
| Mirelman, D; Miron, T; Oron-Herman, M; Rabinkov, A; Rosenthal, T; Sela, BA; Wilchek, M | 1 |
| Baltogiannis, GG; Hatzistergos, KE; Kolettis, TM; Kyriakides, ZS; Malamou-Mitsi, V; Mitsi, AC; Niokou, D; Papalois, A; Pappa, L; Tsalikakis, DG | 1 |
| Chen, P; Wang, S; Xu, J; Yuan, Y; Zhan, L | 1 |
| Brozovich, FV; Chen, FC; Hoit, BD; Ogut, O; Rhee, AY | 1 |
| Kazimierczak, U; Kowalczyk, DW; Kwiatkowska, EP; Mackiewicz, A; Suchorska, W; Wysocki, PJ | 1 |
| Buczko, W; Chabielska, E; Domaniewski, T; Karp, A; Kramkowski, K; Malinowska-Zaprzałka, M; Mogielnicki, A; Opadczuk, A; Wojewódzka-Zelezniakowicz, M | 1 |
| Arsenault, M; Couet, J; Drolet, MC; Gaudreau, M; Lachance, D; Plante, E; Roussel, E | 1 |
| Bell, TD; Brands, MW; Fleming, C; Janardhanan, R; Rojas, M; Springfield, V; Sturgis, LC | 1 |
| Agharazii, M; Larivière, R; Lebel, M; Rodrigue, ME | 1 |
| de Resende, MM; Greene, AS; Kriegel, AJ | 1 |
| Anderson, WP; Edgley, AJ; Evans, RG; Gao, Y; Shweta, A | 1 |
| Carretero, OA; Liao, TD; Peng, H; Peterson, EL; Rhaleb, NE | 1 |
| Gaskin, FS; Kamada, K; Korthuis, RJ; Yusof, M | 1 |
| Brower, GL; Janicki, JS; Levick, SP | 1 |
| Christophi, C; Malcontenti-Wilson, C; Muralidharan, V; Neo, JH | 1 |
| Chen, JH; Guan, YY; Liu, YJ; Qiu, QY; Shi, XL; Wang, GL; Zhang, Z; Zhou, JG | 1 |
| Baybutt, RC; Halder, A; Herndon, BL; Kamal, R; Mein, J; Molteni, A; Reppert, S; Umbehr, J; Van Dillen, C; Xue, Y | 1 |
| Costa-e-Sousa, RH; Marassi, MP; Marinho, A; Martins, OP; Mattos, EC; Olivares, EL; Reis, LC; Trindade, DC; Trindade, RC | 1 |
| Ernsberger, P; Johnson, JL; Koletsky, RJ; Mirelman, D; Rosenthal, T | 1 |
| Jendeková, L; Kojsová, S; Pechánová, O; Sládková, M | 1 |
| Pechánová, O | 1 |
| Bos, AP; Florquin, S; Haitsma, JJ; Lachmann, B; Lutter, R; Merkus, MP; van der Loos, CM; van Woensel, JB; Wösten-van Asperen, RM | 1 |
| Antelava, NA; Gogolauri, MI; Gongadze, NV; Kezeli, TD; Pachkoriia, KZ | 1 |
| Dubinion, JH; Jackson, EK; Mi, Z | 1 |
| Hattori, T; Kase, Y; Koseki, J; Sadakane, C; Takeda, S | 1 |
| Dai, EQ; Di, Y; He, W; Liu, ZQ; Tong, CQ; Wang, YH | 1 |
| Assreuy, J; Fernandes, D; Silva, MA; Stulzer, HK | 1 |
| De Coppi, P; Eaton, S; Hall, NJ; Leon, FF; Malerba, A; Pierro, A; Smith, VV; Zani, A | 1 |
| Fluharty, S; Liu, XT; Rosenfeld, CR; Vidyasagar, D; Willis, BC; Zagariya, AM | 1 |
| Govender, T; Mackraj, I; Ramesar, S | 1 |
| Brozovich, FV; Chen, FC | 1 |
| Araujo, IG; Fonseca, FV; Lepletier, A; Mecawi, AS; Reis, LC | 1 |
| Barbacid, M; Bustelo, XR; Cañamero, M; Guerra, C; Sauzeau, V; Schuhmacher, AJ | 1 |
| Boccagno, JA; Horovitz, ZP; Murthy, VS; Steinbacher, TE; Vollmer, RR | 1 |
| Brooks, B; Brown, PS; Muirhead, EE; Pitcock, JA | 1 |
| Antonaccio, J; Rubin, B | 1 |
| Loyke, HF | 1 |
| Franco, RJ; Kohlmann, O; Marson, O; Ramos, OL; Ribeiro, AB | 1 |
| Bégin, R; Brault, C; Cadieux, A; Forget, G; Sirois, P | 1 |
| Boucher, DM; Cohen, DM; Kaplan, HR; Olszewski, BJ; Ryan, MJ; Singer, RM; Smith, RD | 1 |
| Antonaccio, MJ | 1 |
| Angelini, A; Dario, C; Mazzucato, A; Pauletto, P; Pessina, AC; Scannapieco, G; Semplicini, A; Vescovo, G | 1 |
| Bailie, MD; Donoso, VS; Gonzalez, NC | 1 |
| Doyle, AE; Duffy, SG | 1 |
| Ganten, D; Nicolov, N; Sudakov, C | 1 |
| Bing, RF; Marks, ES; Swales, JD; Thurston, H | 1 |
| Garcon, D; Jourdheuil-Rahmani, D; Masset, D; Rahmani, R; Rolland, PH | 1 |
| Buikema, H; de Graeff, PA; Hegeman, H; Lie, KI; Scholtens, E; van Gilst, WH; van Veldhuisen, DJ | 1 |
| Ogilvie, RI; Zborowska-Sluis, D | 3 |
| Brooks, DP; Contino, LC; Edwards, RM; Gowan, C; Short, BG; Trizna, W | 1 |
| Anderson, BA; Dage, RC; Downs, TR; French, JF | 1 |
| Anthonio, RL; Brodde, OE; de Graeff, PA; Hegeman, H; Lie, KI; Scholtens, E; Schulze, C; van Gilst, WH; van Veldhuisen, DJ; Wesseling, H | 1 |
| Bönner, G; Eisenhauer, T; Fink, E; Krieter, DH; You, HM | 1 |
| Araki, T; Ino, H; Mabuchi, H; Shimizu, M; Takeda, R; Yoshio, H | 1 |
| Jackson, AA; Langley-Evans, SC | 1 |
| Ichikawa, M; Kumagai, H; Kumagai, K; Nishizawa, M; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Araki, M; Imai, S; Kanda, T; Kobayashi, I; Murata, K; Nakano, M; Suzuki, T | 1 |
| Aberg, G; Beyer, S; Kowala, MC; Recce, R | 1 |
| Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
| Fyhrquist, F; Helin, K; Hohenthal, U; Tikkanen, I | 1 |
| Borboa-Osuna, AL; Cruz, C; Cuetos-Martínez, C; Hernández-Llamas, G; Palafox-Cervantes, G; Pedraza-Chaverrí, J; Urrecha-Manzano, J | 1 |
| Adam, A; Closset, J; Couture, R; Décarie, A; Drapeau, G | 1 |
| Booth, B; Broadhurst, KA; Cullen, JJ; Ephgrave, KS | 1 |
| Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC | 1 |
| Koshelev, VB; Kuzenkov, VS; Markov, KhM; Pinelis, VG; Rodionov, IM; Rudneva, LF; Sokolova, RI; Storozhevykh, TP; Tarasova, OS | 1 |
| Aoki, K; Nakajima, T; Setoguchi, M; Yaoka, O | 1 |
| Ichikawa, M; Jimbo, M; Kumagai, H; Matsumura, Y; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Clark, RG; Gillett, N; Jin, H; Ko, A; Paoni, NF; Yang, R | 1 |
| Goldman, S; Johnson, CS; Milavetz, JJ; Morkin, E; Raya, TE | 1 |
| Duan, J; Fernandes, BH; Jaramillo, J; Jung, GL; McLeod, AL | 1 |
| Deckmyn, H; Hoylaerts, MF; Matsuno, H; Stassen, JM; Vermylen, J | 1 |
| Fogo, A; Ichikawa, I; Patel, A; Peten, EP; Striker, GE; Striker, LJ | 1 |
| Adam, A; Couture, R; Decarie, A | 1 |
| Bernátová, I; Pechánová, O; Simko, F | 1 |
| Filart, RA; Kowey, PR; Marinchak, RA; Rials, SJ; Wu, Y; Xu, X | 1 |
| Böhm, M; Ettelbrück, S; Flesch, M; Knorr, A; Pinto, Y; Schiffer, F; Stasch, JP; Zolk, O | 1 |
| Candy, GP; Hartford, C; Norton, GR; Trifunovic, B; Tsotetsi, J; Woodiwiss, AJ | 1 |
| Gomes, MG; Milanez, MC; Mill, JG; Vassallo, DV | 1 |
| Naitoh, T; Shikada, K; Tanaka, S; Yotsumoto, T | 1 |
| Beyer, KH; Follansbee, MH; Griffith, JW; Vesell, ES | 1 |
| Carlyle, W; Chu, C; Cohn, JN; Francis, GS; Hartman, M; Hauer, K; Judd, DL; McDonald, KM | 1 |
| Fujitani, B; Honda, Y; Hosoki, K; Masuda, Y; Minato, H | 1 |
| Ballerio, R; Barberi, L; Bolla, M; Catapano, AL; Ferioli, R; Folco, G; Hernandez, A; Natali, M; Testini, A | 1 |
| Cohen, EP; Fish, BL; Moulder, JE | 1 |
| Rowland, NE | 1 |
| Ali, SM; Anderson, K; Brooks, DP; Contino, LC; Fredrickson, TA; Laping, NJ; Olson, Ba | 1 |
| Black, SC; Driscoll, EM; Lucchesi, BR | 1 |
| Albarrán, OG; García-Robles, R; Rábano, A; Ruilope, LM; Villa, E | 1 |
| Bird, JE; Dambach, DM; Durham, SK; Giancarli, MR; Gitlitz, PH; Kopp, JB; Mozes, MM; Pandya, DG | 1 |
| Dal Ponte, DB; Fogt, DL; Henriksen, EJ; Jacob, S | 1 |
| Buluran, J; Cartier, R; Dagenais, F | 1 |
| Augier, T; Bescond, A; Chareyre, C; Charpiot, P; Fraterno, M; Garçon, D; Rolland, PH | 1 |
| Miyazaki, M; Takai, S | 1 |
| Fitts, DA; Johnson, AK; Lane, JR; Starbuck, EM | 1 |
| Backer, CL; Crawford, SE; Gonzalez-Crussi, F; Hsueh, W; Huang, L; Liu, H; Mavroudis, C; Mu, Y; Takami, H | 1 |
| Linshaw, MA; Milner, LS; Sadeghi-Nejad, A; Yuskiw, M | 1 |
| Gould, RJ; Grossman, W; Kusma, SE; Lynch, JJ; Painter, CA; Stump, GL; Thomas, JM; Wallace, AA | 1 |
| Litwin, SE; Morgan, JP | 1 |
| Colado, MI; Delgado, C; Fernández-Tomé, P; López-Miranda, V; Martínez, ML | 1 |
| Browne, AE; Chatterjee, K; Chou, TM; Lee, RJ; Parmley, WW; Pulukurthy, S; Sievers, RE; Sudhir, K; Sun, Y; Zhu, B | 1 |
| Howard, EF; Landon, EJ; Myers, PR; Steimle, A; Takagi, T; Tamura, M; Tanner, M | 1 |
| Balding, LC; Burrell, LM; Farina, NK; Johnston, CI | 1 |
| Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ | 1 |
| Awad, TA; de Feo , G; Jin, H; Li, W; Ogasawara, A; Paoni, NF; Shimada, B; Wang, F; Williams, PM; Williams, SP; Yang, R | 1 |
| Kulkarni, SK; Raghavendra, V | 1 |
| Goto, K; Kagaya, Y; Kondo, H; Ohta, J; Shirato, K; Sugie, T; Takahashi, J; Takeda, M; Watanabe, J | 1 |
| Browne, AE; Chatterjee, K; Chou, TM; Deedwania, PC; Glantz, SA; Parmley, WW; Pulukurthy, S; Sudhir, K; Sun, YP; Zhu, BQ | 1 |
| Guidi, E; Hollenberg, NK | 1 |
| Andrejak, M; Fournier, A; Mazouz, H; Monge, M; Oprisiu, R | 1 |
| Aubert, JF; Brunner, H; Morgan, T | 1 |
| Cohen, EP; Fish, BL; Molteni, A; Moulder, JE; Taylor, JM; Veno, PA; Ward, WF; Wolfe, LF | 1 |
| Andreini, I; Bonaduce, D; Casini, A; Condorelli, M; D'Armiento, FP; de Nigris, F; De Rosa, G; Mansueto, G; Napoli, C; Sarlo, F; Somma, P | 1 |
| Chaupin, DF; Christie, RM; Daniel, SL; Entman, ML; Gould, KE; Hartley, CJ; Konkol, DL; Michael, LH; Pocius, JS; Sandusky, GE; Taffet, GE; Zachariah, JP | 1 |
| Alagözlü, H; Candan, F | 1 |
| Charles, CJ; Cooper, GJ; Coy, DH; Espiner, EA; Lewis, LK; Nicholls, MG; Rademaker, MT; Richards, AM | 1 |
| Felder, RB; Francis, J; Weiss, RM; Zhang, ZH | 1 |
| Abe, K; Tsunoda, K | 1 |
| Ambrosioni, E; Bacchelli, S; Borghi, C; Degli Esposti, D | 1 |
| Foster, S; Goldman, S; Lee, RW; Meeks, T; Michael, U; Raya, TE | 1 |
| Habior, A | 1 |
| Alam, S; Farkas, P; Rezkalla, S; Turi, ZG | 1 |
| Arcoraci, V; Caputi, AP; Macchiarelli, G; Motta, PM; Nottola, SA; Santoro, G; Squadrito, F; Sturniolo, R; Trimarchi, GR | 1 |
| Humen, DP; Jugdutt, BI; Khan, MI; Schwarz-Michorowski, BL | 1 |
| Jung, CY; Lachaal, M | 1 |
| Antona, A; Di Pasquale, P; Licata, G; Paterna, S; Valenza, M | 1 |
| Baumgartner, HR; Hefti, F; Kuhn, H; Müller, RK; Powell, JS; Rouge, M | 1 |
| Panek, RL; Ryan, MJ; Taylor, DG; Weishaar, RE | 1 |
| Chikugo, T; Hamada, Y; Morita, N; Ohta, Y; Okamoto, K; Shiokawa, H | 1 |
| Nally, JV | 1 |
| Carlson, RP; Chau, TT; Lewin, AC; Walter, TL; Weichman, BM | 1 |
| de Graeff, PA; de Langen, CD; Pinto, YM; van Gilst, WH; van Wijngaarden, J; Wesseling, H | 1 |
| Daugherty, S; Fonken, SJ; Goldman, S; Lee, RW; Morkin, E; Raya, TE; Timmermans, PB; Wong, PC | 1 |
| Arnolda, L; Johnston, CI; McGrath, BP | 1 |
| Ervin, FR; Goldwater, R; Gutkowsa, J; Hamet, P; Hughes, C; Martin, S; Palmour, RM | 1 |
| Carlyle, PF; Cohn, JN; Elbers, T; Hauer, K; Hunter, D; Matthews, J; McDonald, KM | 1 |
| Del Pizzo, R; Gauthier, B; Trachtman, H; Valderrama, E | 1 |
| Blaufox, MD; Lee, HB | 1 |
| Boucek, MM; Chang, R; Synhorst, DP | 1 |
| Arai, M; Matsumoto, S; Nagatsu, T; Shamoto, T; Togari, A | 1 |
| Brosnihan, KB; Ferrario, CM; Saruta, T; Suzuki, H | 1 |
| Hill, GS | 1 |
| Borson, DB; Jacoby, DB; Nadel, JA; Tamaoki, J | 1 |
| Riegger, AJ | 1 |
| Chen, X; Fang, YX; Hu, KL; Liu, ZQ; Su, Z; Wu, WJ; Xiong, WS | 1 |
| Beukers, JJ; Hoedemaeker, PJ; Weening, JJ | 1 |
| Itaya, Y; Kageyama, Y; Kondo, K; Matsukawa, S; Saruta, T; Suzuki, H | 1 |
| Gross, PM; Kadekaro, M | 1 |
9 review(s) available for captopril and Disease Models, Animal
| Article | Year |
|---|---|
Clinical and experimental studies on the use of 3,5-diiodothyropropionic acid, a thyroid hormone analogue, in heart failure.
Topics: Animals; Captopril; Cholesterol; Clinical Trials as Topic; Diiodothyronines; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Heart Failure; Hemodynamics; Humans; Myocardial Infarction; Pilot Projects; Propionates; Rabbits; Randomized Controlled Trials as Topic; Rats; Treatment Outcome; Triglycerides | 2002 |
[Pharmacological effects of captopril].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Cats; Disease Models, Animal; Dogs; Hemodynamics; Humans; Hypertension; Mice; Proline; Rabbits; Rats; Renin | 1981 |
Development and pharmacology of angiotensin converting enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Hemodynamics; Humans; Hypertension; Kinetics; Nervous System; Proline; Renal Circulation; Renin-Angiotensin System; Substrate Specificity; Vascular Resistance; Water-Electrolyte Balance | 1983 |
Emotional stress and arterial hypertension.
Topics: Animals; Blood Pressure; Captopril; Disease Models, Animal; Disease Susceptibility; Dogs; Humans; Hypertension; Injections, Intraventricular; Oligopeptides; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Saralasin; Stress, Psychological | 1982 |
Captopril and angiotensin II receptor antagonist therapy in a pacing model of heart failure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Heart Failure; Humans | 1998 |
[History of nephrology in the past 100 years: Renovascular hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diagnostic Imaging; Disease Models, Animal; History, 19th Century; History, 20th Century; Humans; Hypertension, Renovascular; Juxtaglomerular Apparatus; Nephrology; Renin; Renin-Angiotensin System | 2002 |
ACE-inhibitors and atherosclerosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Diseases; Arteriosclerosis; Captopril; Cilazapril; Disease Models, Animal; Haplorhini; Hyperlipidemias; Lipid Metabolism; Peptidyl-Dipeptidase A; Pyridazines; Rabbits; Rats | 1992 |
Insulin resistance and hypertension.
Topics: Adipose Tissue; Animals; Captopril; Catecholamines; Disease Models, Animal; Fructose; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Lipolysis; Monosaccharide Transport Proteins; Obesity; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1992 |
Renal physiology of renal artery stenosis. Implications for captopril-stimulated renography.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Dogs; Kidney; Radioisotope Renography; Renal Artery Obstruction; Renal Circulation | 1991 |
2 trial(s) available for captopril and Disease Models, Animal
| Article | Year |
|---|---|
Myocardial calcification and hypertension following chronic renal failure and ameliorative effects of furosemide and captopril.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Calcinosis; Captopril; Cardiomyopathies; Disease Models, Animal; Disease Progression; Diuretics; Drug Therapy, Combination; Euthanasia, Animal; Furosemide; Hemodynamics; Hypertension; Kidney Failure, Chronic; Male; Myocardium; Nephrectomy; Rats; Rats, Sprague-Dawley | 2010 |
Clinical and experimental studies on the use of 3,5-diiodothyropropionic acid, a thyroid hormone analogue, in heart failure.
Topics: Animals; Captopril; Cholesterol; Clinical Trials as Topic; Diiodothyronines; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Heart Failure; Hemodynamics; Humans; Myocardial Infarction; Pilot Projects; Propionates; Rabbits; Randomized Controlled Trials as Topic; Rats; Treatment Outcome; Triglycerides | 2002 |
295 other study(ies) available for captopril and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Hydrogen Sulphide Release via the Angiotensin Converting Enzyme Inhibitor Zofenopril Prevents Intimal Hyperplasia in Human Vein Segments and in a Mouse Model of Carotid Artery Stenosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Carotid Stenosis; Cells, Cultured; Disease Models, Animal; Humans; Hydrogen Sulfide; Hyperplasia; Hypertension; Male; Mice; Myocytes, Smooth Muscle; Organ Culture Techniques; Primary Cell Culture; Tunica Intima; Veins | 2022 |
Captopril alleviates oxidative damage in diabetic retinopathy.
Topics: Animals; Captopril; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Endothelial Cells; Glucose; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retina; Retinal Vessels; Streptozocin; Tyrosine; Vascular Endothelial Growth Factor A | 2022 |
Kidney tubule iron loading in experimental focal segmental glomerulosclerosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Deferoxamine; Disease Models, Animal; Female; Glomerulosclerosis, Focal Segmental; Iron; Kidney Tubules, Distal; Male; Mice; Receptors, Cell Surface; Siderophores | 2022 |
Beneficial Effects of Dietary Nitrite on a Model of Nonalcoholic Steatohepatitis Induced by High-Fat/High-Cholesterol Diets in SHRSP5/Dmcr Rats: A Preliminary Study.
Topics: Animals; Captopril; Cholesterol; Diet, High-Fat; Disease Models, Animal; Liver; Liver Cirrhosis; Nitrites; Non-alcoholic Fatty Liver Disease; Rats; Rats, Inbred SHR | 2022 |
Angiotensin converting enzyme inhibitor captopril prevents neuronal overexpression of amyloid-beta and alpha-synuclein in Drosophila melanogaster genetic models of neurodegenerative diseases.
Topics: alpha-Synuclein; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drosophila melanogaster; Humans; Models, Genetic; Neurodegenerative Diseases; Neurons | 2022 |
Blockade of angiotensin-converting enzyme or tumor necrosis factor-α reverses maternal high-fat diet-induced sensitization of angiotensin II hypertension in male rat offspring.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animal Nutritional Physiological Phenomena; Animals; Antihypertensive Agents; Blood Pressure; Brain; Captopril; Diet, High-Fat; Disease Models, Animal; Female; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Pentoxifylline; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin-Angiotensin System; Tumor Necrosis Factor Inhibitors | 2020 |
Antihypertensive effect of Phragmanthera incana (Schum) Balle on NG-nitro-L-Arginine methyl ester (L-NAME) induced hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Arterial Pressure; Biomarkers; Captopril; Disease Models, Animal; Hypertension; Interleukin-6; Kidney; Lipid Peroxidation; Liver; Loranthaceae; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitrites; Oxidative Stress; Plant Extracts; Rats, Wistar; Tumor Necrosis Factor-alpha | 2020 |
Immunomodulatory effects of renin-angiotensin system inhibitors on T lymphocytes in mice with colorectal liver metastases.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carcinoma; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Humans; Liver Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Mice; Renin-Angiotensin System; T-Lymphocytes | 2020 |
Blockade of ERK1/2 activation with U0126 or PEP7 reduces sodium appetite and angiotensin II-induced pressor responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Appetite; Butadienes; Captopril; Disease Models, Animal; Furosemide; Humans; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sodium | 2021 |
Angiotensin converting enzyme inhibition improves cerebrovascular control during exercise in male rats with heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cerebrovascular Circulation; Disease Models, Animal; Electrocardiography; Heart Failure; Male; Physical Conditioning, Animal; Rats; Rats, Inbred Lew | 2021 |
Angiotensin-Converting Enzyme Inhibitor, Captopril, Improves Scar Healing in Hypertensive Rats.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cicatrix; Disease Models, Animal; Humans; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Skin | 2021 |
Inhibitors of angiotensin I converting enzyme potentiate fibromyalgia-like pain symptoms via kinin receptors in mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Captopril; Disease Models, Animal; Enalapril; Fibromyalgia; Male; Mice; Nervous System; Nociceptive Pain; Pain Threshold; Peptidyl-Dipeptidase A; Receptors, Bradykinin; Reserpine; Signal Transduction | 2021 |
Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Echocardiography; Heart Ventricles; Humans; Male; Mice; Microscopy; Myocardial Infarction; Ventricular Function, Left | 2021 |
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Arterial Pressure; Captopril; Disease Models, Animal; Kidney; Liver; Losartan; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Small Interfering | 2021 |
Effects of Captopril and Losartan on Cardiac Stereology in Rats with Renovascular Hypertension.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Heart; Hypertension, Renovascular; Iran; Losartan; Male; Rats; Rats, Sprague-Dawley | 2021 |
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Captopril; Cell Culture Techniques; Disease Models, Animal; Female; Gliosarcoma; Matrix Metalloproteinase 2; Rats; Rats, Inbred F344; Temozolomide; Tumor Cells, Cultured | 2021 |
Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome.
Topics: Acute Radiation Syndrome; Animals; Captopril; Disease Models, Animal; Erythropoietin; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic System; Humans; Leukocytes, Mononuclear; Mice; Oxidation-Reduction; Radiation Injuries, Experimental; Swine; Swine, Miniature; Whole-Body Irradiation | 2021 |
Protective effects of tannic acid on pressure overload-induced cardiac hypertrophy and underlying mechanisms in rats.
Topics: Animals; Apoptosis; Captopril; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelin-1; Fibrosis; Inflammation; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Receptors, Angiotensin; Tannins | 2017 |
Cardiomyopathy development protection after myocardial infarction in rats: Successful competition for major dihydropyridines' common metabolite against captopril.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Blood Pressure; Captopril; Cardiomyopathies; Dihydropyridines; Disease Models, Animal; Heart; Heart Rate; Hemodynamics; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley | 2017 |
Vaccarin administration ameliorates hypertension and cardiovascular remodeling in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Glycosides; Hypertension; Male; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Ventricular Remodeling | 2018 |
Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril.
Topics: Acetylcysteine; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension; Light; Male; Melatonin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ventricular Remodeling | 2017 |
Cerebrovascular recovery after stroke with individual and combined losartan and captopril treatment of SHRsp.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cerebrovascular Circulation; Disease Models, Animal; Drug Combinations; Enzyme Activation; Hypertension; Infarction, Middle Cerebral Artery; Losartan; Middle Cerebral Artery; Nitric Oxide; Protein Kinase C; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Time Factors; Urea; Uric Acid; Vasoconstriction | 2017 |
Pentoxifylline treatment enhances antihypertensive activity of captopril through hemorheological improvement in spontaneously hypertensive rats during development of arterial hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blood Viscosity; Captopril; Cardiac Output; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Humans; Hypertension; Pentoxifylline; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Vascular Resistance | 2017 |
Early intervention by Captopril does not improve wound healing of partial thickness burn wounds in a rat model.
Topics: Administration, Cutaneous; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Burns; Captopril; Cicatrix; Disease Models, Animal; Early Medical Intervention; Inflammation; Macrophages; Male; Mast Cells; Neutrophils; Random Allocation; Rats; Rats, Wistar; Skin; Wound Healing | 2018 |
Time course of angiotensin II dependent vascular and metabolic effects of preeclampsia.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Female; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar | 2017 |
Protective Effects of Pomegranate Juice on Nephrotoxicity Induced by Captopril and Gentamicin in Rats.
Topics: Animals; Biomarkers; Captopril; Cytoprotection; Disease Models, Animal; Fruit and Vegetable Juices; Gentamicins; Kidney; Kidney Diseases; Lythraceae; Male; Malondialdehyde; Natriuresis; Oxidative Stress; Phytotherapy; Plants, Medicinal; Potassium; Rats, Wistar; Renal Elimination; Time Factors | 2017 |
Apocynin combined with drugs as coadjuvant could be employed to prevent and/or treat the chronic kidney disease.
Topics: Acetophenones; Adjuvants, Pharmaceutic; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; Disease Models, Animal; Disease Progression; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Humans; Losartan; Mice; Mice, Inbred C57BL; Oxidative Stress; Renal Insufficiency, Chronic; Treatment Outcome | 2018 |
Association between ACE2/ACE balance and pneumocyte apoptosis in a porcine model of acute pulmonary thromboembolism with cardiac arrest.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Caspase 3; Disease Models, Animal; Female; Gene Expression Regulation; Heart Arrest; Lipopolysaccharides; Lung; Male; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-bcl-2; Pulmonary Embolism; Signal Transduction; Swine | 2018 |
Anti-inflammatory and Antioxidant Effects of Captopril Compared to Methylprednisolone in L-Arginine-Induced Acute Pancreatitis.
Topics: Acute Disease; alpha-Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Captopril; Cytoprotection; Disease Models, Animal; Glutathione; Lipase; Male; Methylprednisolone; Nitric Oxide; Nitric Oxide Synthase Type II; Pancreas; Pancreatitis; Peroxidase; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Captopril Attenuates Cardiovascular and Renal Disease in a Rat Model of Heart Failure With Preserved Ejection Fraction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Comorbidity; Disease Models, Animal; Diuretics; Drug Therapy, Combination; Furosemide; Glomerular Filtration Rate; Heart Failure; Kidney; Male; Metabolic Syndrome; Rats, Zucker; Renal Circulation; Renal Insufficiency, Chronic; Renin-Angiotensin System; Stroke Volume; Ventricular Function, Left; Ventricular Pressure | 2018 |
Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Case-Control Studies; Disease Models, Animal; Epithelial Sodium Channels; Fibrinolysin; Humans; Hydronephrosis; Hypertension; Kidney; Male; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium; Solute Carrier Family 12, Member 3; Up-Regulation; Ureteral Obstruction | 2018 |
Captopril inhibits calpain‑mediated apoptosis of myocardial cells in diabetic rats and improves cardiac function.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calpain; Captopril; Caspase 3; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Heart; Humans; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Ventricular Dysfunction, Left | 2018 |
Post-stroke losartan and captopril treatments arrest hemorrhagic expansion in SHRsp without lowering blood pressure.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain Edema; Captopril; Cerebral Hemorrhage; Cerebrum; Disease Models, Animal; Disease Progression; Losartan; Male; Rats, Inbred WKY; Renin-Angiotensin System; Serum Albumin; Stroke; Time Factors | 2018 |
The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Kidney; Losartan; Malaria; Male; Mice, Inbred C57BL; Plasmodium berghei; Random Allocation; Receptor, Angiotensin, Type 1 | 2018 |
A novel S-nitrosocaptopril monohydrate for pulmonary arterial hypertension: H
Topics: Animals; Antihypertensive Agents; Aorta; Captopril; Crystallization; Disease Models, Animal; Endothelium, Vascular; Heart Ventricles; Humans; Hypertension, Pulmonary; Male; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Stomach; Tissue Culture Techniques; Vascular Resistance; Vasodilation; Vasodilator Agents | 2018 |
Combined Antihypertensive Therapies That Increase Expression of Cardioprotective Biomarkers Associated With the Renin-Angiotensin and Kallikrein-Kinin Systems.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Disease Models, Animal; Gene Expression Regulation; Hypertension; Kallikrein-Kinin System; Losartan; Male; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Renin-Angiotensin System; RNA, Messenger | 2018 |
Sustained Captopril-Induced Reduction in Blood Pressure Is Associated With Alterations in Gut-Brain Axis in the Spontaneously Hypertensive Rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Captopril; Disease Models, Animal; Gastrointestinal Microbiome; Hypertension; Intestinal Mucosa; Male; Permeability; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2019 |
Delayed Captopril Administration Mitigates Hematopoietic Injury in a Murine Model of Total Body Irradiation.
Topics: Acute Radiation Syndrome; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Cell Count; Captopril; Cell Cycle; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gene Expression Regulation; Hematopoiesis; Hematopoietic Stem Cells; Inflammation Mediators; Mice; Radiation Dosage; Radiation Exposure; Radiation-Protective Agents; Time-to-Treatment; Whole-Body Irradiation | 2019 |
Imbalance of angiotensin-converting enzymes affects myocardial apoptosis during cardiac arrest induced by acute pulmonary embolism in a porcine model.
Topics: Acute Disease; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Captopril; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Heart Arrest; Myocardium; Peptidyl-Dipeptidase A; Pulmonary Embolism; Renin-Angiotensin System; Signal Transduction; Swine | 2019 |
Blood pressure lowering effect of Ficus deltoidea var kunstleri in spontaneously hypertensive rats: possible involvement of renin-angiotensin-aldosterone system, endothelial function and anti-oxidant system.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Captopril; Disease Models, Animal; Drugs, Chinese Herbal; Ficus; Hypertension; Losartan; Male; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Plant Extracts; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2019 |
Stress-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Blockade of Angiotensin-Converting Enzyme or Tumor Necrosis Factor-α.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Captopril; Cytokines; Disease Models, Animal; Hypertension; Inflammation Mediators; Male; Microglia; Pentoxifylline; Rats, Long-Evans; Rats, Sprague-Dawley; Renin-Angiotensin System; Stress Disorders, Post-Traumatic; Tumor Necrosis Factor Inhibitors | 2019 |
Effect of captopril on the apoptosis of lung tissue induced by high tidal volume ventilation in vivo.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Disease Models, Animal; Lung; Male; Rats, Wistar; Renin-Angiotensin System; Respiration, Artificial; Tidal Volume; Ventilator-Induced Lung Injury | 2020 |
Virgin olive oil (unfiltered) extract contains peptides and possesses ACE inhibitory and antihypertensive activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Hypertension; Male; Olive Oil; Peptides; Plant Extracts; Rats; Rats, Inbred SHR; Water | 2020 |
Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthracosis; Captopril; Cell Differentiation; Cell Line; Collagen; Disease Models, Animal; Female; Hedgehog Proteins; Humans; Lung; Male; Middle Aged; Myofibroblasts; Oligopeptides; Peptide Fragments; Pulmonary Fibrosis; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Silicosis | 2019 |
The effect of captopril on brain apoptosis after burn injury in rats.
Topics: Animals; Apoptosis; Brain; Burns; Captopril; Disease Models, Animal; Female; Male; Rats; Rats, Wistar; Treatment Outcome | 2013 |
The renin angiotensin system regulates Kupffer cells in colorectal liver metastases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colorectal Neoplasms; Disease Models, Animal; Gadolinium; Kupffer Cells; Liver Neoplasms; Macrophages; Male; Mice; Mice, Inbred CBA; Peptide Fragments; Renin-Angiotensin System | 2013 |
Angiotensin II-converting enzyme inhibition improves survival, ventricular remodeling, and myocardial energetics in experimental aortic regurgitation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Disease Models, Animal; Echocardiography; Energy Metabolism; Extracellular Matrix; Fatty Acids; G-Protein-Coupled Receptor Kinase 5; Hypertrophy, Left Ventricular; Myocardium; Positron-Emission Tomography; Proto-Oncogene Proteins c-akt; Rats; Severity of Illness Index; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2013 |
ACE inhibition with captopril retards the development of signs of neurodegeneration in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Regeneration; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Plaque, Amyloid; Protein Transport; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Transcriptome; Up-Regulation | 2013 |
Hydroxysafflor yellow A attenuates left ventricular remodeling after pressure overload-induced cardiac hypertrophy in rats.
Topics: Animals; Apoptosis; Captopril; Cardiomegaly; Carthamus tinctorius; Chalcone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Medicine, Chinese Traditional; Myocytes, Cardiac; Quinones; Rats; Rats, Wistar; Ventricular Remodeling | 2014 |
NO-dependent endothelial dysfunction in type II diabetes is aggravated by dyslipidemia and hypertension, but can be restored by angiotensin-converting enzyme inhibition and weight loss.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Blood Glucose; Caloric Restriction; Captopril; Combined Modality Therapy; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Dyslipidemias; Endothelium, Vascular; Female; Hypertension; Leptin; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Nitric Oxide; Receptors, LDL; Time Factors; Vasodilation; Vasodilator Agents; Weight Loss | 2013 |
Effect of Cydonia oblonga Mill. fruit and leaf extracts on blood pressure and blood rheology in renal hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Blood Viscosity; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Hypertension, Renal; Male; Medicine, Traditional; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Rosaceae | 2014 |
Effects of antihypertensive and triglyceride-lowering agents on hepatic copper concentrations in rats with fatty liver disease.
Topics: Animals; Antihypertensive Agents; Bezafibrate; Captopril; Copper; Disease Models, Animal; Fatty Liver; Hypolipidemic Agents; Liver; Male; Metallothionein; Rats, Sprague-Dawley; Superoxide Dismutase | 2014 |
The effect of captopril on endometriotic implants in a rat model.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascitic Fluid; Captopril; Chemokine CCL2; Disease Models, Animal; Endometriosis; Endometrium; Female; Gonadotropin-Releasing Hormone; Leuprolide; Peritoneal Diseases; Peritoneum; Rats; Rats, Wistar; Transplantation, Autologous; Vascular Endothelial Growth Factor A | 2014 |
Comparative effects of a novel angiotensin-converting enzyme inhibitor versus captopril on plasma angiotensins after myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Disease Models, Animal; Male; Morpholines; Myocardial Infarction; Peptidyl-Dipeptidase A; Phenols; Rats; Rats, Wistar; Renin-Angiotensin System | 2014 |
Sensitization of sodium appetite: evidence for sustained molecular changes in the lamina terminalis.
Topics: Animals; Appetite Regulation; Behavior, Animal; Captopril; Dehydration; Disease Models, Animal; Dizocilpine Maleate; Furosemide; Hypothalamus; Male; Neuronal Plasticity; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Sodium, Dietary; Time Factors; Up-Regulation | 2014 |
Combining use of captopril and losartan attenuates the progress of Streptococcus pneumoniae-induced tympanosclerosis through the suppression of TGF-β1 expression.
Topics: Animals; Blotting, Western; Calcinosis; Calcium; Captopril; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Ear, Middle; Guinea Pigs; Hearing; Immunohistochemistry; Losartan; Male; Mucous Membrane; Myringosclerosis; Rats, Wistar; Streptococcus pneumoniae; Transforming Growth Factor beta1 | 2014 |
Stereological comparison of the effects of pentoxifylline, captopril, simvastatin, and tamoxifen on kidney and bladder structure after partial urethral obstruction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Estrogen Antagonists; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Male; Pentoxifylline; Rats; Simvastatin; Tamoxifen; Urethral Obstruction; Urinary Bladder Neck Obstruction | 2014 |
Effects of captopril on cardiovascular reflexes and respiratory mechanisms in rats submitted to monocrotaline-induced pulmonary arterial hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Captopril; Disease Models, Animal; Hypertension, Pulmonary; Male; Monocrotaline; Rats; Rats, Wistar; Vascular Remodeling | 2015 |
Mechanism and consequences of the shift in cardiac arginine metabolism following ischaemia and reperfusion in rats.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginase; Arginine; Captopril; Disease Models, Animal; Isolated Heart Preparation; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Polyamines; Rats; Recovery of Function; Renin-Angiotensin System; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Ventricular Function, Left | 2015 |
Renin-angiotensin system (RAS) blockade attenuates growth and metastatic potential of renal cell carcinoma in mice.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carcinoma, Renal Cell; Disease Models, Animal; Immunohistochemistry; Kidney Neoplasms; Losartan; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Renin-Angiotensin System | 2015 |
The angiotensin converting enzyme inhibitor, captopril, prevents the hyperactivity and impulsivity of neurokinin-1 receptor gene 'knockout' mice: sex differences and implications for the treatment of attention deficit hyperactivity disorder.
Topics: Analysis of Variance; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Attention Deficit Disorder with Hyperactivity; Captopril; Choice Behavior; Disease Models, Animal; Female; Hyperkinesis; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pyridines; Reaction Time; Receptors, Neurokinin-1; Sex Differentiation | 2015 |
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Captopril; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypertension, Renal; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Random Allocation; Rats, Wistar; Renin; RNA, Messenger | 2015 |
Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Autophagy; Blood Pressure; Captopril; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Metoprolol; Mice, Inbred C57BL; Myocytes, Cardiac; Signal Transduction; Tetrazoles; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Absence of Cardiac Benefit with Early Combination ACE Inhibitor and Beta Blocker Treatment in mdx Mice.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Cardiac Catheterization; Cardiomyopathies; Disease Models, Animal; Drug Therapy, Combination; Magnetic Resonance Imaging; Male; Metoprolol; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocardium; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure | 2015 |
Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, CD; Aorta; Atherosclerosis; Captopril; Cholesterol; Cytokines; Dendritic Cells; Diet, Atherogenic; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Lipids; Male; Rats, Sprague-Dawley; Simvastatin; T-Lymphocytes, Regulatory | 2015 |
Thirst and sodium appetite in rats with experimental nephrotic syndrome.
Topics: Angiotensin II; Animals; Antibiotics, Antineoplastic; Appetite; Blood Pressure; Bronchodilator Agents; Captopril; Disease Models, Animal; Diuretics; Doxorubicin; Drinking; Furosemide; Isoproterenol; Male; Nephrotic Syndrome; Rats; Rats, Sprague-Dawley; Renin; Sodium; Thirst; Vasoconstrictor Agents | 2015 |
The effect of angoroside C on pressure overload-induced ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Captopril; Collagen; Constriction, Pathologic; Coumaric Acids; Disease Models, Animal; Endothelin-1; Heart; Heart Rate; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Scrophularia; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Trisaccharides; Ventricular Remodeling | 2015 |
Antihypertensive and cardioprotective effects of the dipeptide isoleucine-tryptophan and whey protein hydrolysate.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiotonic Agents; Dipeptides; Disease Models, Animal; Humans; Hypertension; Isoleucine; Male; Protein Hydrolysates; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tryptophan; Whey | 2015 |
Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colitis; Colon; Corticosterone; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Enteritis; Intestinal Mucosa; Jejunal Diseases; Jejunum; Male; Mice, Inbred BALB C; Peptidyl-Dipeptidase A; Pyridines | 2015 |
Antihypertensive Properties of a Novel Morphologic Derivative (4-tert-buthyl-2,6-bis(thiomorpholine-4-ilmethyl)phenol).
Topics: Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hypertension; Male; Morpholines; Peptidyl-Dipeptidase A; Phenols; Rats, Inbred SHR; RNA, Messenger; Up-Regulation; Vasodilation; Vasodilator Agents | 2016 |
Apamin-Sensitive Small Conductance Calcium-Activated Potassium Channels were Negatively Regulated by Captopril in Volume-Overload Heart Failure Rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apamin; Calcium; Captopril; Disease Models, Animal; Echocardiography; Gene Expression; Heart Failure; Hemodynamics; Male; Myocytes, Cardiac; Rats; Small-Conductance Calcium-Activated Potassium Channels | 2016 |
Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in L-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT₁R Expression.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Carthamus tinctorius; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Time Factors; Vasodilation | 2016 |
The effect of captopril on the expression of MMP-9 and the prognosis of neurological function in herpes simplex encephalitis mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Brain Edema; Captopril; CD11b Antigen; Cells, Cultured; Collagen Type IV; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis, Herpes Simplex; Female; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Microglia; NADPH Oxidases; Nervous System Diseases; Reactive Oxygen Species | 2016 |
Captopril improves postresuscitation hemodynamics protective against pulmonary embolism by activating the ACE2/Ang-(1-7)/Mas axis.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Pressure; Biomarkers; Capillary Permeability; Captopril; Cardiopulmonary Resuscitation; Disease Models, Animal; Enzyme Activation; Female; Heart Arrest; Hemodynamics; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Artery; Pulmonary Edema; Pulmonary Embolism; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Sus scrofa; Thrombolytic Therapy; Time Factors; Vascular Resistance; Ventricular Function, Right; Ventricular Pressure | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Hypertension; Male; Myocardium; Rats, Wistar; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2016 |
N-acetyl-seryl-aspartyl-lysyl-proline mediates the anti-fibrotic properties of captopril in unilateral ureteric obstructed BALB/C mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Indoles; Kidney; Kidney Diseases; Male; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Peptidyl-Dipeptidase A; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Signal Transduction; Thiazolidines; Transforming Growth Factor beta1; Ureteral Obstruction | 2018 |
Responsive mesoporous silica nanoparticles for sensing of hydrogen peroxide and simultaneous treatment toward heart failure.
Topics: alpha-Cyclodextrins; Animals; Animals, Genetically Modified; Captopril; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Heart Failure; Hydrogen Peroxide; Nanoparticles; Porosity; Silicon Dioxide; Zebrafish | 2017 |
Late blood pressure reduction in SHR subjected to transient captopril treatment in youth: possible mechanisms.
Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Drug Administration Schedule; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Sympathetic Nervous System; Vasoconstriction; Vasodilator Agents | 2008 |
Protective effect of captopril against cisplatin-induced nephrotoxicity in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Captopril; Cisplatin; Creatinine; Disease Models, Animal; Endothelin-1; Free Radical Scavengers; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Nitric Oxide; Rats; Rats, Wistar | 2008 |
Involvement of angiotensin converting enzyme in cerebral hypoperfusion induced anterograde memory impairment and cholinergic dysfunction in rats.
Topics: Acetylcholine; Amnesia, Anterograde; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Captopril; Cholinesterases; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2008 |
Regulation of oxygen utilization by angiotensin II in chronic kidney disease.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Kidney Diseases; Losartan; Nitric Oxide Synthase; Oxygen Consumption; Rats; Sodium | 2009 |
Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Captopril; Disease Models, Animal; Electric Stimulation; Hypertension; Imidazoles; Mesenteric Arteries; Neuropeptide Y; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Splanchnic Circulation; Sympathetic Nervous System | 2008 |
Effect of carvedilol on pulse pressure and left ventricular hypertrophy in spontaneously hypertensive rats with adriamycin nephropathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Captopril; Carbazoles; Carvedilol; Creatinine; Disease Models, Animal; Disease Progression; Doxorubicin; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hypertension; Hypertrophy, Left Ventricular; Kidney; Kidney Diseases; Kidney Failure, Chronic; Propanolamines; Proteinuria; Rats; Rats, Inbred SHR; Time Factors | 2009 |
Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Disease Models, Animal; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Wistar; Ventricular Dysfunction, Right | 2008 |
Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems.
Topics: Acute Disease; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Disease Models, Animal; Extracellular Matrix Proteins; Gene Expression Profiling; Gene Expression Regulation; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Metoprolol; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Severity of Illness Index; Time Factors | 2009 |
Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles.
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cell Fractionation; Cell Membrane; Cytoplasmic Vesicles; Disease Models, Animal; Diuresis; Hypertension; Infusions, Intravenous; Kidney Tubules, Distal; Male; Microscopy, Immunoelectron; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3; Symporters; Time Factors | 2009 |
Inhibition of brain renin-angiotensin system improves diastolic cardiac function following myocardial infarction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Diastole; Disease Models, Animal; Echocardiography; Electrocardiography; Injections, Intraventricular; Male; Myocardial Infarction; Rats; Rats, Wistar; Renin-Angiotensin System | 2009 |
Captopril reduces deposition of collagen in lamina propria and muscular layers of the bladder and ureter in neonatal dogs with partial urethral obstruction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Captopril; Collagen; Disease Models, Animal; Dogs; Male; Mucous Membrane; Muscle, Smooth; Ureter; Urethral Obstruction; Urinary Bladder | 2008 |
Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomyopathies; Diastole; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dystrophin; Gene Expression Regulation; Glucocorticoids; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; Prednisolone; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sarcolemma; Treatment Outcome; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left | 2009 |
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carbocyanines; Cardiovascular Agents; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Fibrillar Collagens; Fibroblasts; Fibrosis; Losartan; Mice; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; Oligopeptides; Predictive Value of Tests; Spironolactone; Technetium; Tomography, Emission-Computed, Single-Photon; Ventricular Function, Left; Ventricular Remodeling | 2009 |
Involvement of central angiotensin II type 1 receptors in LPS-induced systemic vasopressin release and blood pressure regulation in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Disease Models, Animal; Drug Therapy, Combination; Endotoxemia; Injections, Intraventricular; Injections, Subcutaneous; Lipopolysaccharides; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2009 |
Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies.
Topics: Albuminuria; Animals; Biomarkers; Captopril; Disease Models, Animal; Hypertension; Kidney; Mice; Mice, Transgenic; Myocardium; Random Allocation; Reference Values; Renin; Renin-Angiotensin System; RNA; Sensitivity and Specificity | 2009 |
[Effects of Astragalus membranaccus on cardiac function and SERCA2a gene expression in myocardial tissues of rats with chronic heart failure].
Topics: Animals; Astragalus propinquus; Captopril; Chronic Disease; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Heart; Heart Failure; Heart Ventricles; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2009 |
Inhibition of renin-angiotensin system in experimental acute pancreatitis in rats: a new therapeutic target?
Topics: Amylases; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Ceruletide; Disease Models, Animal; Imidazoles; Injections, Intraperitoneal; Male; Neutrophil Infiltration; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Rats; Rats, Wistar; Renin-Angiotensin System; Taurocholic Acid; Tetrazoles; Treatment Outcome | 2010 |
NMR-based metabolomics of urine for the atherosclerotic mouse model using apolipoprotein-E deficient mice.
Topics: Animals; Antihypertensive Agents; Apolipoproteins E; Atherosclerosis; Biomarkers; Captopril; Disease Models, Animal; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Mice, Knockout; Reference Standards | 2009 |
Combinational chelation therapy abrogates lead-induced neurodegeneration in rats.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Biogenic Amines; Calcium; Captopril; Chelating Agents; Cytochromes c; Disease Models, Animal; DNA Damage; Drug Therapy, Combination; Exploratory Behavior; Lead Poisoning, Nervous System; Learning; Male; Membrane Potential, Mitochondrial; Memory; Mitochondria; Motor Activity; Nerve Degeneration; Neurons; Nitric Oxide; Organometallic Compounds; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer | 2009 |
Combination of captopril and allopurinol retards fructose-induced metabolic syndrome.
Topics: Allopurinol; Angiotensin-Converting Enzyme Inhibitors; Animal Feed; Animals; Antimetabolites; Body Weight; Captopril; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Energy Metabolism; Fructose; Insulin Resistance; Male; Metabolic Syndrome; Rats; Rats, Sprague-Dawley | 2009 |
Cardioprotective effect of ornitho-kinin in an anesthetized, open-chest chicken model of acute coronary occlusion.
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cardiotonic Agents; Chickens; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Kinins; Myocardial Infarction; Preoperative Care; Vascular Resistance; Vasodilator Agents | 2009 |
Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Cardiomyopathy, Dilated; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography, Doppler; Follow-Up Studies; Hypertrophy, Left Ventricular; Losartan; Male; Nifedipine; Rats; Rats, Wistar; Renin-Angiotensin System; Treatment Outcome; Vasodilator Agents; Ventricular Function, Left | 2009 |
Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Histone Deacetylase Inhibitors; Hypertrophy, Right Ventricular; Ligation; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Valproic Acid | 2010 |
Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Blood Pressure; Captopril; Cardiomegaly; Disease Models, Animal; Endothelin-1; Endothelin-Converting Enzymes; Hypertension, Renovascular; Kidney; Male; Metalloendopeptidases; Ocimum basilicum; Plant Extracts; Rats; Rats, Wistar | 2010 |
Angiotensin-converting enzyme (ACE) inhibitors exacerbate histological damage and motor deficits after experimental traumatic brain injury.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain Injuries; Captopril; Cerebral Cortex; Disease Models, Animal; Enalapril; Gene Expression Regulation; Male; Motor Activity; Movement Disorders; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Substance P | 2010 |
Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive rats.
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Fumarates; Heart; Heart Ventricles; Hypertension; Hypertrophy; Irbesartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles | 2010 |
[Antifibrotic effects of oxymatrine in mice with chronic viral myocarditis].
Topics: Alkaloids; Animals; Antiviral Agents; Captopril; Chronic Disease; Disease Models, Animal; Down-Regulation; Enterovirus B, Human; Fibrosis; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Quinolizines; Transforming Growth Factor beta1; Virus Diseases | 2010 |
Mitigating effects of captopril and losartan on lung histopathology in a rat model of fat embolism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Therapy, Combination; Embolism, Fat; Losartan; Lung; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2011 |
Captopril potentiates the anticonvulsant activity of carbamazepine and lamotrigine in the mouse maximal electroshock seizure model.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Antihypertensive Agents; Captopril; Disease Models, Animal; Electroshock; Epilepsy, Tonic-Clonic; Male; Mice | 2010 |
Lipopolysaccharide reduces sodium intake and sodium excretion in dehydrated rats.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antidiuretic Agents; Appetite; Blood Pressure; Body Temperature; Captopril; Dehydration; Disease Models, Animal; Diuretics; Drinking; Furosemide; Heart Rate; Lipopolysaccharides; Male; Peptides; Rats; Saline Solution, Hypertonic; Sodium Chloride; Thirst | 2011 |
Effects of captopril on the cysteamine-induced duodenal ulcer in the rat.
Topics: Animals; Biomarkers; Captopril; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Free Radical Scavengers; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
[A study of the effect of captopril on prevention and treatment of hypertrophy and its mechanism].
Topics: Animals; Captopril; Cardiomyopathy, Hypertrophic; Catechols; Disease Models, Animal; Myocardium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2001 |
[Protective effects of captopril against lung injury in rats with severe acute pancreatitis].
Topics: Amylases; Angiotensin II; Animals; Captopril; Disease Models, Animal; Lung; Lung Injury; Male; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2010 |
[Effects of ventricular arrhythmia during early ischemic myocardium with captopril].
Topics: Animals; Arrhythmias, Cardiac; Captopril; Disease Models, Animal; Electric Stimulation Therapy; Myocardial Ischemia; Rabbits; Ventricular Fibrillation | 2006 |
Re: Davis et al., "Timing of captopril administration determines radiation protection or radiation sensitization in a murine model of total body irradiation".
Topics: Animals; Captopril; Disease Models, Animal; Hematopoietic Stem Cells; Male; Radiation Protection; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Whole-Body Irradiation | 2011 |
Protein kinase C inhibition ameliorates functional endothelial insulin resistance and vascular smooth muscle cell hypersensitivity to insulin in diabetic hypertensive rats.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Femoral Artery; Hypertension; Indoles; Insulin; Insulin Resistance; Male; Maleimides; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myography; Protein Deficiency; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Telemetry; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
Effect of captopril on serum lipid levels and cardiac mitochondrial oxygen consumption in experimentally-induced hypercholesterolemia in rabbits.
Topics: Adenosine Diphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Captopril; Cell Respiration; Disease Models, Animal; Hypercholesterolemia; Lipids; Male; Mitochondria, Heart; Oxygen; Oxygen Consumption; Rabbits; Spectrophotometry; Time Factors | 2011 |
The anti-oxidant and anti-apoptotic effects of nebivolol and zofenopril in a model of cerebral ischemia/reperfusion in rats.
Topics: Animals; Antioxidants; Apoptosis; Benzopyrans; Brain Ischemia; Captopril; Cerebral Cortex; Disease Models, Animal; Ethanolamines; Female; Nebivolol; Oxidants; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome | 2012 |
Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats.
Topics: Acute Kidney Injury; Animals; Antibodies, Anti-Idiotypic; Antihypertensive Agents; Blood Pressure; Captopril; Diltiazem; Disease Models, Animal; Female; Fibrosis; Hydrochlorothiazide; Hypertension; Male; Proteinuria; Rats; Rats, Inbred Dahl; Sex Characteristics; Sodium Chloride, Dietary; Transforming Growth Factor beta | 2012 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury | 2012 |
nNOS expression in the brain of rats after burn and the effect of the ACE inhibitor captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Burns; Captopril; Disease Models, Animal; Immunohistochemistry; Injections, Intraperitoneal; Male; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 2013 |
Antihypertensive effects of extract from Picrasma quassiodes (D. Don) Benn. in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hypertension; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Phytotherapy; Picrasma; Plant Components, Aerial; Rats; Rats, Inbred SHR; Superoxide Dismutase | 2013 |
Plasma microRNAs serve as biomarkers of therapeutic efficacy and disease progression in hypertension-induced heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Captopril; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Heart Failure; Hypertension; Male; MicroRNAs; Natriuretic Peptide, Brain; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sodium Chloride; Treatment Outcome | 2013 |
Protection against ischemia and improvement of cerebral blood flow in genetically hypertensive rats by chronic pretreatment with an angiotensin II AT1 antagonist.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Brain; Brain Ischemia; Calcium Channel Blockers; Captopril; Cerebrovascular Circulation; Disease Models, Animal; Drug Administration Schedule; Hypertension; Infarction, Middle Cerebral Artery; Male; Nicardipine; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Tetrazoles | 2002 |
An experimental study of therapeutic effect of ACEI on chemical-induced ARDS in rats.
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Endothelium, Vascular; Hypertension, Pulmonary; Male; Oleic Acid; Rats; Rats, Wistar; Respiratory Distress Syndrome | 2002 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
Low doses of angiotensin converting enzyme inhibitors and angiotensin type 1 blockers have a synergistic effect but high doses are less than additive.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Hypertension; Losartan; Rats; Rats, Inbred SHR | 2002 |
Antioxidants modulate adenosine metabolism in rat mesangial cells cultured under high glucose conditions.
Topics: Adenosine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Cell Culture Techniques; Disease Models, Animal; Fibroblasts; Free Radical Scavengers; Glomerular Mesangium; Glutathione; Hyperglycemia; Melatonin; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasodilator Agents | 2002 |
Angiotensins in plasma of hypertensive rats and human.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Disease Models, Animal; Enalapril; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar | 2003 |
Modulation of cutaneous inflammation by angiotensin-converting enzyme.
Topics: Administration, Cutaneous; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Captopril; Croton Oil; Dermatitis, Allergic Contact; Dermatitis, Irritant; Dinitrofluorobenzene; Disease Models, Animal; Female; Genetic Carrier Screening; Homozygote; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptor, Bradykinin B2 | 2003 |
Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Captopril; Disease Models, Animal; Endothelium, Vascular; Female; Hemodynamics; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Vasodilation; Ventricular Fibrillation | 2003 |
Chronic inhibition of nitric oxide synthase induces hypertension and cardiomyocyte mitochondrial and myocardial collagen remodelling in the absence of hypertrophy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Collagen; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Mitochondria, Heart; Models, Cardiovascular; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Predictive Value of Tests; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Severity of Illness Index; Time Factors; Treatment Outcome | 2003 |
A novel HIV-1 transgenic rat model of childhood HIV-1-associated nephropathy.
Topics: Age Factors; AIDS-Associated Nephropathy; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Female; HIV-1; Immunohistochemistry; Kidney Glomerulus; Male; Microscopy, Electron; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; RNA, Viral | 2003 |
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance | 2003 |
S-nitrosocaptopril: acute in-vivo pulmonary vasodepressor effects in pulmonary hypertensive rats.
Topics: Administration, Oral; Animals; Captopril; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Lung; Male; Rats; Rats, Wistar; Time Factors; Vasoconstrictor Agents; Vasodilation | 2003 |
Effects of increased intra-abdominal pressure and volume expansion on renal function in the rat.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Disease Models, Animal; Kidney; Male; Pneumoperitoneum, Artificial; Pressure; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Tetrazoles | 2003 |
Age-related decline in spatial learning and memory: attenuation by captopril.
Topics: Aging; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Male; Maze Learning; Memory; Memory Disorders; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Space Perception | 2003 |
Anti-fibrogenic effects of captopril and candesartan cilexetil on the hepatic fibrosis development in rat. The effect of AT1-R blocker on the hepatic fibrosis.
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Carbon Tetrachloride; Cell Count; Disease Models, Animal; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Tetrazoles; Treatment Outcome | 2003 |
Captopril and vascular endothelial growth factor in a mouse model of retinopathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blotting, Western; Captopril; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hyperoxia; Mice; Mice, Inbred C57BL; Retinal Neovascularization; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2003 |
Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers; Captopril; Disease Models, Animal; Echocardiography; Endothelin-1; Genetic Markers; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptors, Aryl Hydrocarbon; RNA, Messenger; Ventricular Myosins | 2003 |
Allylmercaptocaptopril: a new antihypertensive drug.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Disulfides; Fructose; Hypertension; Hypolipidemic Agents; Insulin; Rats; Rats, Sprague-Dawley; Sulfinic Acids; Triglycerides | 2004 |
Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.
Topics: Allopurinol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cell Adhesion; Chemokines; Chemotaxis, Leukocyte; Colon; Constriction; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation; Inflammation; Ischemia; Leukocyte Count; Leukocytes; Losartan; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2004 |
Angiotensin-converting enzyme inhibitor captopril prevents volume overload cardiomyopathy in experimental chronic aortic valve regurgitation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Gene Expression; Hypertrophy, Left Ventricular; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2004 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; Captopril; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hindlimb; Histamine; Histamine N-Methyltransferase; Hypotension; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Male; Medulla Oblongata; Naphthyridines; Pyridines; Pyrimethamine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Resuscitation; Shock, Hemorrhagic; Time Factors; Vascular Resistance | 2004 |
[Prophylactic use of angiotensin-converting enzyme inhibitors in indomethacin-induced ulcer and erosion lesions of the stomach].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Captopril; Disease Models, Animal; Enalapril; Gastric Mucosa; Indomethacin; Lisinopril; Male; Rats; Stomach Ulcer; Treatment Outcome | 2004 |
Captopril suppresses post-transplantation angiogenic activity in rat allograft coronary vessels.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Culture Techniques; Cell Movement; Cornea; Coronary Artery Disease; Disease Models, Animal; Endothelial Cells; Heart Transplantation; Male; Neovascularization, Physiologic; Platelet Activating Factor; Rats; Rats, Inbred F344; Rats, Inbred Lew; Vascular Endothelial Growth Factor A | 2004 |
Prevention of fibrosis in experimental colitis by captopril: the role of tgf-beta1.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colitis; Colon; Disease Models, Animal; Fibrosis; Male; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Chemoprotective effects of captopril against cyclophosphamide-induced genotoxicity in mouse bone marrow cells.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antimutagenic Agents; Antioxidants; Bone Marrow Cells; Captopril; Chemoprevention; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Erythroblasts; Glutathione; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagens | 2005 |
The effect of angiotensin-converting enzyme inhibitors on experimental colitis in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colitis; Collagen; Colon; Disease Models, Animal; Enzyme Inhibitors; Female; Glutathione; Lisinopril; Male; Malondialdehyde; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2005 |
Influence of carvedilol on chronic renal failure progression in spontaneously hypertensive rats with adriamycin nephropathy.
Topics: Animals; Antibiotics, Antineoplastic; Antihypertensive Agents; Blood Pressure; Captopril; Carbazoles; Carvedilol; Disease Models, Animal; Disease Progression; Doxorubicin; Drug Therapy, Combination; Female; Kidney Failure, Chronic; Nephritis; Propanolamines; Rats; Rats, Inbred SHR | 2005 |
[The effect of captopril and valsartan on preventing the formation of atherosclerotic plaque].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Arteriosclerosis; Captopril; Cholesterol, Dietary; Disease Models, Animal; Endothelium, Vascular; Male; Rabbits; Tetrazoles; Ultrasonography; Valine; Valsartan | 2005 |
AT1 receptor in paraventricular nucleus mediates the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Blotting, Western; Bradykinin; Captopril; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Hemodynamics; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System | 2005 |
[PTEN negatively regulates isoproterenol-induced cardiac hypertrophy and effects of captopril on PTEN expression].
Topics: Animals; Captopril; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Isoproterenol; Myocardium; PTEN Phosphohydrolase; Rats; Rats, Wistar; RNA, Messenger | 2005 |
Exogenously administered substance P and neutral endopeptidase inhibitors stimulate fibroblast proliferation, angiogenesis and collagen organization during Achilles tendon healing.
Topics: Achilles Tendon; Animals; Captopril; Cell Proliferation; Collagen; Disease Models, Animal; Drug Combinations; Fibroblasts; Male; Neovascularization, Physiologic; Neprilysin; Protease Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Rupture; Substance P; Tendon Injuries; Thiorphan; Treatment Outcome; Wound Healing | 2005 |
Mechanisms of increased vascular superoxide production in an experimental model of idiopathic dilated cardiomyopathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Captopril; Cardiomyopathy, Dilated; Cell Adhesion Molecules; Cricetinae; Disease Models, Animal; Female; Guanylate Cyclase; Heart Failure; Male; Mesocricetus; Microfilament Proteins; Myocardium; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Phosphoproteins; Receptors, Cytoplasmic and Nuclear; Renin-Angiotensin System; Soluble Guanylyl Cyclase; Superoxides | 2005 |
The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cyclopropanes; Disease Models, Animal; Disulfides; Homocysteine; Hypertension; Hypoglycemic Agents; Insulin; Male; Metabolic Syndrome; Rats; Rats, Sprague-Dawley; Risk Factors; Sulfinic Acids; Treatment Outcome; Triglycerides | 2005 |
Early, intracoronary growth hormone administration attenuates ventricular remodeling in a porcine model of myocardial infarction.
Topics: Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Growth Hormone; Humans; Myocardial Infarction; Neovascularization, Pathologic; Swine; Ventricular Remodeling | 2006 |
Captopril, an Angiotensin-converting enzyme inhibitor, attenuates the severity of acute pancreatitis in rats by reducing expression of matrix metalloproteinase 9.
Topics: Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillary Permeability; Captopril; Disease Models, Animal; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 9; Oligopeptides; Pancreas; Pancreatitis, Acute Necrotizing; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 2006 |
Captopril prevents myosin light chain phosphatase isoform switching to preserve normal cGMP-mediated vasodilatation.
Topics: Animals; Antihypertensive Agents; Captopril; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Heart Failure; Male; Myosin-Light-Chain Phosphatase; Myosins; Nitric Oxide; Protein Isoforms; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2006 |
Captopril, an angiotensin-converting enzyme inhibitor, promotes growth of immunogenic tumors in mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Sarcoma, Experimental; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2006 |
Antithrombotic effect of tissue and plasma type angiotensin converting enzyme inhibitors in experimental thrombosis in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Disease Models, Animal; Enalapril; Fibrillar Collagens; Fibrin; Hemostasis; Male; Perindopril; Platelet Adhesiveness; Platelet Aggregation; Quinapril; Rats; Rats, Wistar; Regional Blood Flow; Tetrahydroisoquinolines; Thromboembolism | 2006 |
Treatment of combined aortic regurgitation and systemic hypertension: Insights from an animal model study.
Topics: Animals; Aortic Valve Insufficiency; Captopril; Disease Models, Animal; Endomyocardial Fibrosis; Heart Ventricles; Hypertension; Hypertrophy; Male; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY | 2006 |
Blood pressure early in diabetes depends on a balance between glomerular filtration rate and the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium; Time Factors | 2006 |
Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Drug Therapy, Combination; Erythropoietin; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Losartan; Nephrectomy; Rats; Rats, Wistar; Recombinant Proteins; Renin-Angiotensin System; Reserpine; Time Factors; Uremia | 2006 |
Combined effects of low-dose spironolactone and captopril therapy in a rat model of genetic hypertrophic cardiomyopathy.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Congenic; Atrial Natriuretic Factor; Blood Pressure; Captopril; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Injections, Subcutaneous; Myocardium; Organ Size; Random Allocation; Rats; Rats, Inbred Strains; Spironolactone; Ventricular Function, Left; Weight Loss | 2006 |
Total peripheral resistance responsiveness during the development of secondary renal hypertension in dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Cardiac Output; Disease Models, Animal; Dogs; Enalapril; Ganglionic Blockers; Hypertension, Renovascular; Male; Pentolinium Tartrate; Phenylephrine; Vascular Resistance; Vasoconstrictor Agents | 2007 |
Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Captopril; Disease Models, Animal; Enzyme Activation; Fibrosis; Heart; Hypertension; Inflammation; Kidney; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Rats | 2007 |
Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Cell Adhesion; Chymases; Disease Models, Animal; Endothelial Cells; Imidazoles; Intestines; Ischemia; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; NADPH Oxidases; Pyridines; Pyrimidinones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Calcitonin Gene-Related Peptide; Reperfusion Injury; Tetrazoles; Valine; Valsartan; Venules | 2007 |
Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arteriovenous Shunt, Surgical; Captopril; Compliance; Disease Models, Animal; Heart Failure; Hypertrophy, Left Ventricular; Lisinopril; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Myocardial Contraction; Myocardium; Quinapril; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Time Factors; Venae Cavae; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2007 |
Effect of ACE inhibitors and angiotensin II receptor antagonists in a mouse model of colorectal cancer liver metastases.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Colorectal Neoplasms; Disease Models, Animal; Irbesartan; Liver Neoplasms; Male; Mice; Mice, Inbred CBA; Microscopy, Electron, Scanning; Necrosis; Tetrazoles | 2007 |
Alteration of volume-regulated chloride movement in rat cerebrovascular smooth muscle cells during hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Size; Cerebral Arteries; Chlorides; Disease Models, Animal; Genistein; Hypertension; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Vanadates | 2007 |
Effects on cytokines and histology by treatment with the ACE inhibitor captopril and the antioxidant retinoic acid in the monocrotaline model of experimentally induced lung fibrosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Cytokines; Disease Models, Animal; Male; Monocrotaline; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Tretinoin | 2007 |
Role of renin-angiotensin system in development of heart failure induced by myocardial infarction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Echocardiography; Electrocardiography; Heart Failure; Myocardial Infarction; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System; Ventricular Function, Left | 2007 |
Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Captopril; Disease Models, Animal; Disulfides; Dose-Response Relationship, Drug; Drug Combinations; Female; Hypoglycemic Agents; Insulin; Male; Metabolic Syndrome; Rats; Rats, Inbred SHR; Sulfinic Acids; Treatment Outcome | 2007 |
Chronic and acute effects of different antihypertensive drugs on femoral artery relaxation of L-NAME hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Diuretics; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Femoral Artery; Heart Ventricles; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2007 |
Contribution of captopril thiol group to the prevention of spontaneous hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Cardiomegaly; Cyclic GMP; Disease Models, Animal; Enalapril; Hypertension; Male; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Sulfhydryl Compounds; Time Factors; Up-Regulation | 2007 |
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.
Topics: Angiotensin II; Animals; Apoptosis; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Losartan; Lung Diseases; Male; Peptidyl-Dipeptidase A; Pulmonary Gas Exchange; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiration, Artificial; Sensitivity and Specificity | 2008 |
[Comparative characteristic of angiotensin-converting enzyme inhibitor--captopril and the angiotensin II receptor blokers--losartan action on the oxidative metabolism in experimental hyperlipidemia in rabbits].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Catalase; Disease Models, Animal; Hyperlipidemias; Lipids; Losartan; Nitric Oxide; Oxidative Stress; Rabbits; Superoxide Dismutase; Treatment Outcome | 2007 |
Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Captopril; Chlorisondamine; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ganglionic Blockers; Hydralazine; Hypertension; Pentanoic Acids; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Thiazolidines; Vasodilator Agents | 2008 |
Saireito probably prevents mesangial cell proliferation in HIGA mice via PDGF-BB tyrosine kinase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Becaplermin; Captopril; Cell Proliferation; Cell Survival; Cells, Cultured; Chalcones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Flavonoids; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Mesangial Cells; Mice; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Receptors, Platelet-Derived Growth Factor; Up-Regulation | 2007 |
Effect of yiqi huoxue recipe on cardiac function and ultrastructure in regression of pressure overload-induced myocardial hypertrophy in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiomegaly; Disease Models, Animal; Drugs, Chinese Herbal; Heart; Male; Myocardium; Phytotherapy; Pressure; Rats; Rats, Wistar; Remission Induction; Ventricular Remodeling | 2007 |
Development of controlled release captopril granules coated with ethylcellulose and methylcellulose by fluid bed dryer.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cellulose; Chemistry, Pharmaceutical; Crystallography, X-Ray; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Female; Hypertension; Kinetics; Methylcellulose; Microscopy, Electron, Scanning; Models, Chemical; Povidone; Powder Diffraction; Powders; Rats; Rats, Wistar; Solubility; Technology, Pharmaceutical | 2008 |
Captopril reduces the severity of bowel damage in a neonatal rat model of necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Body Weight; Captopril; Disease Models, Animal; Enterocolitis, Necrotizing; Female; Ileum; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Splanchnic Circulation; Survival Rate | 2008 |
Meconium increases type 1 angiotensin II receptor expression and alveolar cell death.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Cell Death; Cells, Cultured; Disease Models, Animal; Humans; Immunohistochemistry; Infant, Newborn; Losartan; Male; Meconium; Meconium Aspiration Syndrome; Pulmonary Alveoli; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2008 |
The antihypertensive effects of quercetin in a salt-sensitive model of hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dimethyl Sulfoxide; Disease Models, Animal; Hypertension; Kidney; Male; Quercetin; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; RNA, Messenger; Sodium Chloride, Dietary | 2008 |
Gene expression profiles of vascular smooth muscle show differential expression of mitogen-activated protein kinase pathways during captopril therapy of heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Disease Models, Animal; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Heart Failure; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocardial Infarction; Oligonucleotide Array Sequence Analysis; Portal Vein; Rats; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2008 |
Oestrogenic influence on brain AT1 receptor signalling on the thirst and sodium appetite in osmotically stimulated and sodium-depleted female rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Contraceptive Agents; Disease Models, Animal; Diuretics; Drinking; Estradiol; Estrogens; Female; Furosemide; Hyponatremia; Losartan; Ovariectomy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Signal Transduction; Thirst | 2008 |
A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Gene Expression Regulation; Hypertension; Intellectual Disability; Kidney; Mice; Mutation; Phenotype; ras Proteins; Recombination, Genetic; Signal Transduction; Syndrome | 2008 |
Antihypertensive activity of captopril (SQ 14,225), an orally active inhibitor of angiotensin converting enzyme in conscious two-kidney perinephritic hypertensive dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Hypertension, Renal; Male; Perinephritis; Proline; Renin | 1981 |
Possible link between converting enzyme inhibition and renomedullary interstitial cells.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Hypertension; Hypertension, Renal; Kidney Medulla; Nephrectomy; Rabbits; Ureter | 1981 |
Effect of converting enzyme and angiotensin II inhibitors in chronic one kidney bipolar ligated hypertension.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Hypertension, Renal; Hypertension, Renovascular; Male; Proline; Rats; Renin | 1981 |
Etiopathogenesis of excess methylprednisolone arterial hypertension in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Hypertension; Male; Methylprednisolone; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Saralasin | 1981 |
Lack of correlation between serum angiotensin-converting enzyme levels and asbestosis in man, sheep and guinea-pig.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Animals; Asbestosis; Captopril; Child; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Male; Peptidyl-Dipeptidase A; Sheep; Species Specificity | 1983 |
Antihypertensive profile of the angiotensin-converting enzyme inhibitors CI-906 and CI-907.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Dipeptides; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Enalapril; Female; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Indoles; Isoquinolines; Kinetics; Male; Quinapril; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Tetrahydroisoquinolines | 1984 |
[Evaluation of the efficacy of various hypotensive drugs in broad-breasted white turkeys as an experimental model of arterial hypertension with high catecholamine levels].
Topics: Animals; Antihypertensive Agents; Captopril; Catecholamines; Disease Models, Animal; Furosemide; Hypertension; Labetalol; Male; Oxprenolol; Rats; Turkeys; Verapamil | 1983 |
Role of the renin-angiotensin system in hypertension after coarctation of the aorta.
Topics: Animals; Aortic Coarctation; Captopril; Disease Models, Animal; Hypertension; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1984 |
Exchangeable sodium, plasma renin activity and blood pressure changes during the development of 2 kidney 1 clip hypertension, and after subsequent contralateral nephrectomy.
Topics: Animals; Blood Pressure; Captopril; Disease Models, Animal; Drinking; Hypertension, Renal; Hypertension, Renovascular; Nephrectomy; Rats; Rats, Inbred Strains; Renin; Sodium | 1982 |
Vasodepressor property of the converting enzyme inhibitor captopril (SQ 14 225): the role of factors other than renin-angiotensin blockade in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Disease Models, Animal; Female; Hypertension; Nephrectomy; Proline; Rats; Renin; Saralasin | 1980 |
Alterations of methionine fluxes and incorporation in intestines of miniature pigs fed a diet high in caseinate are restricted by angiotensin-converting enzyme inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Caseins; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Epithelium; Homocysteine; Hydrochlorothiazide; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methionine; Random Allocation; Sodium Chloride Symporter Inhibitors; Swine; Swine, Miniature; Tritium | 1995 |
Effect of ibopamine on ventricular remodeling after experimental myocardial infarction: a comparison with captopril.
Topics: Animals; Captopril; Catecholamines; Coronary Circulation; Deoxyepinephrine; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Heart Ventricles; Male; Myocardial Infarction; Rats; Rats, Wistar | 1994 |
Effect of captopril treatment on total and central vascular capacitance in dogs with chronic heart failure.
Topics: Analysis of Variance; Animals; Blood Pressure; Blood Volume; Captopril; Cardiac Output; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Heart Failure; Pulmonary Wedge Pressure; Vascular Resistance | 1994 |
SB 203220: a novel angiotensin II receptor antagonist and renoprotective agent.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Kidney Failure, Chronic; Male; Naphthalenes; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes | 1995 |
Dual inhibition of angiotensin-converting enzyme and neutral endopeptidase in rats with hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Benzazepines; Blood Pressure; Captopril; Disease Models, Animal; Diuresis; Hypertension; Hypertension, Renal; Male; Neprilysin; Protease Inhibitors; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium | 1995 |
Relation between myocardial beta-adrenoceptor density and hemodynamic and neurohumoral changes in a rat model of chronic myocardial infarction: effects of ibopamine and captopril.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chronic Disease; Deoxyepinephrine; Disease Models, Animal; Dopamine Agonists; Drug Therapy, Combination; Heart Rate; Hemodynamics; Isoproterenol; Male; Myocardial Infarction; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Ventricular Pressure | 1995 |
Anaphylactoid reactions during haemodialysis in sheep are associated with bradykinin release.
Topics: Acrylic Resins; Acrylonitrile; Anaphylaxis; Animals; Bradykinin; Captopril; Disease Models, Animal; Female; Hemodynamics; Male; Membranes, Artificial; Radioimmunoassay; Renal Dialysis; Sheep | 1995 |
Effects of angiotensin-converting enzyme inhibitor and aldosterone antagonist on myocardial collagen in cardiomyopathic hamsters.
Topics: Aging; Animals; Body Weight; Canrenoic Acid; Captopril; Cardiomyopathies; Collagen; Cricetinae; Disease Models, Animal; Heart; Hydroxyproline; Male; Organ Size | 1995 |
Captopril attenuates pacing-induced acute heart failure by increasing total vascular capacitance.
Topics: Acute Disease; Animals; Blood Vessels; Captopril; Compliance; Disease Models, Animal; Dogs; Heart Failure; Hemodynamics; Pacemaker, Artificial; Vasodilator Agents | 1993 |
Captopril normalises systolic blood pressure in rats with hypertension induced by fetal exposure to maternal low protein diets.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Captopril; Diet, Protein-Restricted; Disease Models, Animal; Female; Hypertension; Lung; Peptidyl-Dipeptidase A; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Renin; Renin-Angiotensin System | 1995 |
Different responses of renal blood flow and sympathetic nerve activity to captopril and nicardipine in conscious renal hypertensive rabbits.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Disease Models, Animal; Female; Heart Rate; Hypertension, Renal; Kidney; Nicardipine; Norepinephrine; Rabbits; Regional Blood Flow; Renal Circulation; Sympathetic Nervous System; Vascular Resistance; Vasodilation | 1995 |
Chronic effect of losartan in a murine model of dilated cardiomyopathy: comparison with captopril.
Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Cardiomyopathy, Dilated; Disease Models, Animal; Female; Imidazoles; Losartan; Mice; Mice, Inbred DBA; Organ Size; Tetrazoles | 1995 |
Regression of early atherosclerosis in hyperlipidemic hamsters induced by fosinopril and captopril.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Arteriosclerosis; Blood Pressure; Captopril; Cell Count; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cricetinae; Diet, Atherogenic; Disease Models, Animal; Foam Cells; Fosinopril; Heart Rate; Hyperlipidemias; Image Processing, Computer-Assisted; Macrophages; Male | 1995 |
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan | 1995 |
Inhibition of either angiotensin-converting enzyme or neutral endopeptidase induces both enzymes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Captopril; Dioxolanes; Dipeptides; Disease Models, Animal; Enzyme Induction; Heart Failure; Kidney; Ligation; Lung; Male; Neprilysin; Organ Size; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Wistar; Regression Analysis; Renin | 1994 |
Role of the renin-angiotensin system in arterial hypertension secondary to acute unilateral urinary obstruction.
Topics: Aldosterone; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dogs; Hypertension; Renin; Renin-Angiotensin System; Ureteral Obstruction | 1994 |
Development of digoxigenin-labeled peptide: application to chemiluminoenzyme immunoassay of bradykinin in inflamed tissues.
Topics: 3-Mercaptopropionic Acid; Acute Disease; Amino Acid Sequence; Animals; Bradykinin; Captopril; Digoxigenin; Disease Models, Animal; Immunoenzyme Techniques; Inflammation; Luminescent Measurements; Lysine Carboxypeptidase; Male; Molecular Sequence Data; Molecular Structure; Rats; Rats, Wistar | 1994 |
Captopril decreases stress ulceration without affecting gastric perfusion during canine hemorrhagic shock.
Topics: Analysis of Variance; Animals; Captopril; Disease Models, Animal; Dogs; Gastric Mucosa; Regional Blood Flow; Regression Analysis; Shock, Hemorrhagic; Splanchnic Circulation; Stomach Ulcer; Stress, Physiological; Treatment Outcome | 1994 |
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Bradykinin; Captopril; Cardiomegaly; Dioxoles; Disease Models, Animal; Heart Failure; Hormones; Male; Molecular Sequence Data; Myocardial Infarction; Myocardium; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin | 1994 |
[The effect of captopril on the arterial pressure, structural resistance and vascular reactivity of the kidney in rats with nephrogenic hypertension].
Topics: Animals; Blood Pressure; Captopril; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Hydronephrosis; Hypertension, Renovascular; Male; Phenylephrine; Pyelonephritis; Rats; Renal Artery; Vascular Resistance | 1993 |
[Antihypertensive activity of the angiotensin converting enzyme inhibitor quinapril HCl: (S)-2-[(S)-N-[(S)-1-ethoxycarbonyl-3-phenylpropyl) alanyl]-1,2,3,4- tetrahydro-3-isoquinolinecarboxylic acid monohydrochloride in various hypertensive animal models].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Heart Rate; Hypertension; Hypertension, Renal; Isoquinolines; Male; Quinapril; Rats; Rats, Inbred SHR; Rats, Wistar; Tetrahydroisoquinolines | 1993 |
Central and peripheral vasopressin interact differently with sympathetic nervous system and renin-angiotensin system in renal hypertensive rabbits.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Clonidine; Disease Models, Animal; Female; Hypertension, Renovascular; Kidney; Nicardipine; Norepinephrine; Rabbits; Renin-Angiotensin System; Sympathetic Nervous System | 1993 |
Beneficial effects of growth hormone and insulin-like growth factor-1 in experimental heart failure in rats treated with chronic ACE inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Captopril; Cardiac Output; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Growth Hormone; Heart Failure; Heart Rate; Hypertrophy, Left Ventricular; Insulin-Like Growth Factor I; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Stroke Volume; Vascular Resistance; Ventricular Function, Left | 1995 |
Survival after myocardial infarction in rats: captopril versus losartan.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Confounding Factors, Epidemiologic; Disease Models, Animal; Hemodynamics; Imidazoles; Losartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Survival Analysis; Tetrazoles; Time Factors | 1996 |
A novel renal hypertensive guinea pig model for comparing different inhibitors of the renin-angiotensin system.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Disease Models, Animal; Guinea Pigs; Heart Rate; Hypertension, Renal; Male; Pyridines; Renin; Renin-Angiotensin System; Thiazoles | 1996 |
Fast and reproducible vascular neointima formation in the hamster carotid artery: effects of trapidil and captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carotid Stenosis; Cell Division; Cricetinae; Disease Models, Animal; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Reference Values; Reproducibility of Results; Time Factors; Trapidil; Tunica Intima | 1995 |
The molecular basis of increased glomerulosclerosis after blockade of the renin angiotensin system in growth hormone transgenic mice.
Topics: Actins; Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; Blood Pressure; Body Weight; Captopril; Collagen; Collagenases; Creatinine; Disease Models, Animal; Extracellular Matrix; Gelatinases; Glomerular Filtration Rate; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Growth Hormone; Imidazoles; Juxtaglomerular Apparatus; Kidney; Kidney Glomerulus; Lymphotoxin-alpha; Mice; Mice, Transgenic; Muscle, Smooth; Organ Size; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Thymidine | 1994 |
Effects of captopril and Icatibant on bradykinin (BK) and des [Arg9] BK in carrageenan-induced edema.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Carrageenan; Disease Models, Animal; Edema; Foot Diseases; Hindlimb; Inflammation; Male; Rats; Rats, Wistar; Receptors, Bradykinin; Time Factors | 1996 |
Captopril prevents NO-deficient hypertension and left ventricular hypertrophy without affecting nitric oxide synthase activity in rats.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Enzyme Inhibitors; Evaluation Studies as Topic; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Time Factors | 1996 |
Regression of left ventricular hypertrophy with captopril restores normal ventricular action potential duration, dispersion of refractoriness, and vulnerability to inducible ventricular fibrillation.
Topics: Action Potentials; Animals; Captopril; Disease Models, Animal; Electrophysiology; Hypertrophy, Left Ventricular; Rabbits; Ventricular Fibrillation | 1997 |
Angiotensin receptor antagonism and angiotensin converting enzyme inhibition improve diastolic dysfunction and Ca(2+)-ATPase expression in the sarcoplasmic reticulum in hypertensive cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Calcium-Transporting ATPases; Captopril; Cardiomyopathy, Hypertrophic; Diastole; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Mice; Mice, Transgenic; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sarcoplasmic Reticulum; Tetrazoles | 1997 |
Myocardial stiffness is attributed to alterations in cross-linked collagen rather than total collagen or phenotypes in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Body Weight; Captopril; Collagen; Cross-Linking Reagents; Diastole; Disease Models, Animal; Hydralazine; Hypertension; Male; Myocardium; Organ Size; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Solubility; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right | 1997 |
Effects of captopril on interstitial collagen in the myocardium after infarction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Fibrosis; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar | 1997 |
Effects of specific antagonists of angiotensin II receptors and captopril on diabetic nephropathy in mice.
Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertrophy; Imidazoles; Kidney Diseases; Losartan; Male; Mice; Mice, Inbred Strains; Pyridines; Receptors, Angiotensin; Streptozocin | 1997 |
Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Guanidines; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Kidney; Kidney Function Tests; Male; Molecular Weight; Pyrazines; Rats; Rats, Sprague-Dawley; Serum Albumin; Streptozocin | 1997 |
Effect of delayed intervention with ACE-inhibitor therapy on myocyte hypertrophy and growth of the cardiac interstitium in the rat model of myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Drug Administration Schedule; Endothelium, Vascular; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Renin | 1997 |
Alacepril, an angiotensin-converting enzyme inhibitor, prevents cerebral vasospasm in subarachnoid hemorrhage model in rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Basilar Artery; Captopril; Disease Models, Animal; Enalapril; In Vitro Techniques; Ischemic Attack, Transient; Male; Muscle Relaxation; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage | 1997 |
Delapril slows the progression of atherosclerosis and maintains endothelial function in cholesterol-fed rabbits.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Body Weight; Captopril; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Data Interpretation, Statistical; Diet, Atherogenic; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypercholesterolemia; Indans; Male; Nitric Oxide; Nitroglycerin; Norepinephrine; Rabbits; Triglycerides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1998 |
Radiation nephropathy is treatable with an angiotensin converting enzyme inhibitor or an angiotensin II type-1 (AT1) receptor antagonist.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Imidazoles; Kidney; Kidney Diseases; Kidney Function Tests; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Survival Rate; Tetrazoles; Time Factors; Treatment Outcome | 1998 |
NaCl appetite in two strains of rat reported to be resistant to mineralocorticoid-induced hypertension.
Topics: Analysis of Variance; Animals; Appetite Regulation; Captopril; Desoxycorticosterone; Disease Models, Animal; Drinking; Enalapril; Furosemide; Hypertension; Male; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Sodium Chloride; Species Specificity | 1998 |
Angiotensin-converting enzyme inhibition attenuates proteinuria and renal TGF-beta 1 mRNA expression in rats with chronic renal disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Captopril; Disease Models, Animal; Gene Expression; Kidney; Kidney Cortex; Kidney Failure, Chronic; Nephrectomy; Peptidyl-Dipeptidase A; Proteinuria; Rats; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta | 1998 |
Effect of ramiprilat or captopril on myocardial infarct size: assessment in canine models of ischemia alone and ischemia with reperfusion.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Heart Rate; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Ramipril | 1998 |
Effects of chronic combined treatment with captopril and pravastatin on the progression of insulin resistance and cardiovascular alterations in an experimental model of obesity in dogs.
Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Captopril; Cardiovascular Diseases; Cholesterol; Coronary Vessels; Disease Models, Animal; Disease Progression; Dogs; Drug Therapy, Combination; Heart; Insulin; Insulin Resistance; Linear Models; Male; Multivariate Analysis; Myocardium; Obesity; Pravastatin; Triglycerides | 1998 |
Captopril prevents nephropathy in HIV-transgenic mice.
Topics: AIDS-Associated Nephropathy; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Female; Gene Expression; Genes, Viral; HIV-1; Humans; Kidney; Male; Mice; Mice, Transgenic; Proteinuria; RNA, Messenger; Transforming Growth Factor beta | 1998 |
Interactions of captopril and verapamil on glucose tolerance and insulin action in an animal model of insulin resistance.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Calcium Channel Blockers; Captopril; Disease Models, Animal; Drug Interactions; Female; Glucose; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Oxidation-Reduction; Phosphorylation; Rats; Rats, Zucker; Verapamil | 1998 |
[Effects of chronic administration of captopril on vascular reactivity of the rat aorta].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Disease Models, Animal; Endothelium, Vascular; Hypertension; Muscle Relaxation; Rats | 1997 |
Hyperhomocysteinemia induces elastolysis in minipig arteries: structural consequences, arterial site specificity and effect of captopril-hydrochlorothiazide.
Topics: Animals; Antihypertensive Agents; Aorta, Abdominal; Captopril; Coronary Vessels; Disease Models, Animal; Elastic Tissue; Elasticity; Elastin; Hydrochlorothiazide; Hyperhomocysteinemia; Swine; Swine, Miniature | 1998 |
Antiatherosclerotic effect of alacepril, an angiotensin-converting enzyme inhibitor, in monkeys fed a high-cholesterol diet.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Blood Pressure; Blood Proteins; Captopril; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Disease Models, Animal; Female; Follow-Up Studies; Heart Rate; Macaca; Male; Peptidyl-Dipeptidase A | 1999 |
Effects of bile duct ligation and captopril on salt appetite and renin-aldosterone axis in rats.
Topics: Aldosterone; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Appetite Regulation; Captopril; Cholestasis; Common Bile Duct; Disease Models, Animal; Drinking; Drinking Behavior; Ligation; Male; Rats; Rats, Long-Evans; Renin; Sodium Chloride | 1999 |
Captopril and platelet-activating factor (PAF) antagonist prevent cardiac allograft vasculopathy in rats: role of endogenous PAF and PAF-like compounds.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Captopril; Coronary Disease; Disease Models, Animal; Drug Therapy, Combination; Heart Transplantation; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Homologous; Treatment Outcome; Triazoles; Ventricular Remodeling | 1999 |
Captopril reduces the proteinuric effect of human growth hormone in adriamycin nephrosis.
Topics: Animals; Captopril; Cholesterol; Disease Models, Animal; Doxorubicin; Growth Hormone; Kidney Diseases; Male; Proteinuria; Rats; Rats, Sprague-Dawley | 1999 |
EXP3174, the AII antagonist human metabolite of losartan, but not losartan nor the angiotensin-converting enzyme inhibitor captopril, prevents the development of lethal ischemic ventricular arrhythmias in a canine model of recent myocardial infarction.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Captopril; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Heart Ventricles; Humans; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardial Ischemia; Tetrazoles; Time Factors | 1999 |
Effects of stimulation frequency on calcium transients in noninfarcted myocardium: modulation by chronic captopril treatment.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Calcium Signaling; Captopril; Disease Models, Animal; Electric Stimulation; Heart Failure; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley | 1999 |
Modulation of adrenergic receptors during left ventricular hypertrophy development and after regression by captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Disease Models, Animal; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta | 1999 |
Comparative effects of pretreatment with captopril and losartan on cardiovascular protection in a rat model of ischemia-reperfusion.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Captopril; Disease Models, Animal; Electrocardiography; Female; Heart Rate; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Treatment Outcome; Ventricular Fibrillation | 2000 |
Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation in synthetic diet-fed rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Captopril; Cardiac Glycosides; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Gene Expression; Imidazoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Weight Gain | 2000 |
Beneficial renal and cardiac effects of vasopeptidase inhibition with S21402 in heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Captopril; Cardiovascular System; Disease Models, Animal; Female; Heart Failure; Hormones; Kidney; Methionine; Myocardial Infarction; Neprilysin; Propionates; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Water | 2000 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collagen; Constriction, Pathologic; Disease Models, Animal; Echocardiography; Hydroxyproline; Hypertrophy, Left Ventricular; In Vitro Techniques; Isoproterenol; Male; Myocardium; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley; Regression Analysis; Systole; Ventricular Dysfunction, Left; Ventricular Remodeling | 2001 |
Effects of early angiotensin-converting enzyme inhibition on cardiac gene expression after acute myocardial infarction.
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Gene Expression; Heart; Heart Function Tests; Heart Rate; Male; Myocardial Infarction; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2001 |
AT1 receptor antagonism enhances angiotensin-II-facilitated carrageenan-induced paw edema.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carrageenan; Disease Models, Animal; Drug Synergism; Edema; Extremities; Inflammation; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Vasoconstrictor Agents | 2000 |
Gene expression and in situ localization of diacylglycerol kinase isozymes in normal and infarcted rat hearts: effects of captopril treatment.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Body Weight; Captopril; Diacylglycerol Kinase; Disease Models, Animal; Gene Expression; Granulocytes; Heart Ventricles; Immunohistochemistry; In Situ Hybridization; Isoenzymes; Macrophages; Male; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar; RNA, Messenger; Ventricular Remodeling | 2001 |
Comparative effects of ACE inhibitors and an angiotensin receptor blocker on atherosclerosis and vascular function.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteriosclerosis; Captopril; Cholesterol; Disease Models, Animal; Isoquinolines; Kinins; Losartan; Male; Nitric Oxide; Quinapril; Rabbits; Receptors, Angiotensin; Tetrahydroisoquinolines; Vasoconstriction; Vasodilation | 2001 |
Different reactivity to angiotensin II of peripheral and renal arteries in spontaneously hypertensive rats: effect of acute and chronic angiotensin converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sodium, Dietary | 1986 |
[In contrast to captopril and enalapril, losartan does not increase mortality of gerbils after carotid ligation].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Surgical Procedures; Carotid Arteries; Disease Models, Animal; Enalapril; Gerbillinae; Ligation; Losartan; Myocardial Ischemia; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Survival Analysis | 2001 |
Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiomegaly; Circadian Rhythm; Cross-Over Studies; Disease Models, Animal; France; Heart; Hypertension, Renovascular; Kidney; Losartan; Models, Cardiovascular; Organ Size; Rats; Rats, Wistar; Renin; Sodium, Dietary; Telemetry | 2001 |
Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bone Marrow Transplantation; Captopril; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Fibrosis; Imidazoles; Kidney Diseases; Male; Radiotherapy; Rats; Tetrazoles; Time Factors | 2001 |
Chronic treatment with sulfhydryl angiotensin-converting enzyme inhibitors reduce susceptibility of plasma LDL to in vitro oxidation, formation of oxidation-specific epitopes in the arterial wall, and atherogenesis in apolipoprotein E knockout mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Stenosis; Apolipoproteins E; Arteries; Arteriosclerosis; Blood Pressure; Captopril; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Epitopes; Immunohistochemistry; Lipid Peroxidation; Lipoproteins, LDL; Male; Mice; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Peptidyl-Dipeptidase A; Random Allocation; Sulfhydryl Reagents; Time Factors; Treatment Outcome | 2001 |
Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure.
Topics: Age Factors; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Captopril; Cardiomegaly; Coronary Disease; Disease Models, Animal; Heart Failure; Heart Septum; Ligation; Male; Mice; Mice, Inbred C57BL; Multivariate Analysis; Myocardial Infarction; Survival Rate | 2002 |
Captopril inhibits the pulmonary toxicity of paraquat in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Combinations; Glutathione; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Lung; Male; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Combined angiotensin-converting enzyme inhibition and adrenomedullin in an ovine model of heart failure.
Topics: Adrenomedullin; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiotonic Agents; Creatinine; Disease Models, Animal; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Kidney; Peptides; Potassium; Sheep; Sodium; Vasodilator Agents | 2002 |
The renin-angiotensin-aldosterone system excites hypothalamic paraventricular nucleus neurons in heart failure.
Topics: Action Potentials; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Heart Failure; Injections, Intra-Arterial; Injections, Intravenous; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardial Ischemia; Neurons; Paraventricular Hypothalamic Nucleus; Pressoreceptors; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Spironolactone | 2002 |
Captopril and ANP: changes in renal hemodynamics, glomerular-ANP receptors and guanylate cyclase activity in rats with heart failure.
Topics: Animals; Atrial Natriuretic Factor; Captopril; Cardiac Output, Low; Disease Models, Animal; Down-Regulation; Guanylate Cyclase; Hemodynamics; Kidney; Kidney Glomerulus; Kinetics; Male; Myocardial Infarction; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Renal Circulation; Renin-Angiotensin System | 1992 |
[Effect of captopril on glutathione level in the liver and paracetamol-induced liver damage in rats].
Topics: Acetaminophen; Animals; Captopril; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Liver; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1992 |
Deleterious cardiac effects of captopril during acute myocardial ischaemia in the dog.
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Animals; Captopril; Coronary Disease; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart; Male; Myocardium; Regional Blood Flow | 1992 |
Effects of captopril on the development of rat doxorubicin nephropathy.
Topics: Animals; Captopril; Disease Models, Animal; Doxorubicin; Kidney; Male; Microscopy, Electron, Scanning; Nephritis; Rats; Rats, Inbred Strains | 1992 |
Effect of left ventricular unloading with captopril on remodelling and function during healing of anterior transmural myocardial infarction in the dog.
Topics: Animals; Captopril; Collagen; Disease Models, Animal; Dogs; Echocardiography; Female; Hemodynamics; Male; Myocardial Infarction; Random Allocation; Ventricular Function, Left | 1992 |
Effects of captopril on the ACE-tissular system and on models of experimental ischaemia in isolated rabbit hearts.
Topics: Animals; Arrhythmias, Cardiac; Captopril; Coronary Circulation; Coronary Disease; Disease Models, Animal; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Rabbits | 1992 |
The proliferative response to vascular injury is suppressed by angiotensin-converting enzyme inhibition.
Topics: Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Captopril; Cell Division; Cilazapril; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Growth Substances; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Pyridazines; Rats; Verapamil | 1990 |
Development of a high renin model of hypertension in the cynomolgus monkey.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Disease Models, Animal; Hypertension, Renovascular; Macaca fascicularis; Male; Oligopeptides; Renal Artery Obstruction; Renin; Saralasin | 1991 |
Therapy and prevention of hypertension of M-SHRSP.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cerebrovascular Disorders; Diet; Disease Models, Animal; Disease Susceptibility; Fish Flour; Hydralazine; Hypertension, Malignant; Male; Organophosphorus Compounds; Proline; Rats; Rats, Inbred SHR | 1991 |
Evidence for a role of bradykinin in experimental pain models.
Topics: Animals; Benzoquinones; Bradykinin; Captopril; Disease Models, Animal; Female; Male; Mice; Mice, Inbred Strains; Pain; Pain Measurement; Phenanthrolines; Rats | 1991 |
Converting enzyme inhibition after experimental myocardial infarction in rats: comparative study between spirapril and zofenopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Enalapril; Heart; Heart Rate; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Rats, Inbred Strains | 1991 |
Hemodynamic effects of direct angiotensin II blockade compared to converting enzyme inhibition in rat model of heart failure.
Topics: Administration, Oral; Angiotensin II; Animals; Body Weight; Captopril; Cardiac Output, Low; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Hemodynamics; Imidazoles; Losartan; Male; Myocardial Infarction; Rats; Rats, Inbred Strains; Tetrazoles; Ventricular Function, Left | 1991 |
Vasopressin and angiotensin II contribute equally to the increased afterload in rabbits with heart failure.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Cardiac Output; Disease Models, Animal; Female; Heart Failure; Male; Rabbits; Vascular Resistance; Vasopressins | 1991 |
Characterization of a primate model of hypertension. The response of hypertensive and normotensive male vervets (Cercopithecus aethiops) to cold pressor stress, captopril administration, and acute bolus of atrial natriuretic factor.
Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Determination; Bloodletting; Captopril; Chlorocebus aethiops; Cold Temperature; Disease Models, Animal; Diuresis; Furosemide; Hypertension; Male | 1990 |
Early ventricular remodeling after myocardial damage and its attenuation by converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Disease Models, Animal; Dogs; Heart Injuries; Heart Ventricles | 1990 |
The renal functional and structural consequences of corticosteroid and angiotensin-converting enzyme inhibitor therapy in chronic puromycin aminonucleoside nephropathy.
Topics: Adrenal Cortex Hormones; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Kidney Failure, Chronic; Male; Methylprednisolone; Nephrotic Syndrome; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains | 1990 |
Technetium-99m MAG-3 clearances after captopril in experimental renovascular hypertension.
Topics: Animals; Captopril; Diagnosis, Differential; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Iodohippuric Acid; Male; Nephrectomy; Oligopeptides; Organometallic Compounds; Rats; Rats, Inbred Strains; Technetium; Technetium Tc 99m Mertiatide | 1989 |
Renin-angiotensin II response to the hemodynamic pathology of ovines with ventricular septal defect.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Furosemide; Heart Septal Defects, Ventricular; Hemodynamics; Renin; Renin-Angiotensin System; Saralasin; Sheep; Sheep Diseases | 1989 |
Elevation of blood pressure in young rats fed a low calcium diet. Effects of nifedipine and captopril.
Topics: Animals; Blood Pressure; Body Weight; Calcium; Captopril; Diet; Disease Models, Animal; Heart Rate; Hyperparathyroidism; Hypertension; Male; Nifedipine; Rats; Rats, Inbred Strains | 1989 |
Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Captopril; Catecholamines; Disease Models, Animal; Dogs; Epinephrine; Hexamethonium; Hexamethonium Compounds; Hypertension, Malignant; Hypertension, Renovascular; Neuropeptides; Norepinephrine; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1987 |
Drug-associated glomerulopathies.
Topics: Amyloidosis; Animals; Captopril; Cyclosporins; Disease Models, Animal; Gold; Heroin Dependence; Humans; Hydrocarbons; Immune Complex Diseases; Kidney Diseases; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mercury; Nephrotic Syndrome; Penicillamine; Puromycin Aminonucleoside; Serum Sickness; Solvents; Tetradecanoylphorbol Acetate | 1986 |
Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase.
Topics: Animals; Captopril; Disease Models, Animal; Ferrets; In Vitro Techniques; Influenza A virus; Leucine; Leupeptins; Metalloendopeptidases; Muscle Contraction; Muscle, Smooth; Neprilysin; Orthomyxoviridae Infections; Thiorphan; Tiopronin; Trachea | 1988 |
Role of vasopressin in experimental heart failure.
Topics: Animals; Aortic Valve Stenosis; Arginine Vasopressin; Blood Pressure; Captopril; Disease Models, Animal; Dogs; Heart Failure; Pulmonary Valve Stenosis; Rats; Renin-Angiotensin System; Teprotide; Water-Electrolyte Balance | 1988 |
Comparative effects of captopril, nitroprusside, dopamine and lanatoside C on a new model of rabbit congestive heart failure.
Topics: Animals; Captopril; Disease Models, Animal; Dopamine; Female; Ferricyanides; Heart Failure; Hemodynamics; Lanatosides; Male; Myocardial Contraction; Nitroprusside; Rabbits | 1988 |
Pharmacological and dietary intervention in experimental models of chronic renal disease.
Topics: Animals; Captopril; Dietary Proteins; Disease Models, Animal; Doxorubicin; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Nephrectomy; Proteinuria; Rats; Rats, Inbred Strains | 1988 |
Central and peripheral contributions of the renin-angiotensin system in two models of experimental hypertension in rats.
Topics: Animals; Blood Pressure; Brain; Captopril; Disease Models, Animal; Hypertension; Hypertension, Renovascular; Male; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Sympathetic Nervous System | 1986 |
Elevated glucose utilization in the subfornical organ during dehydration.
Topics: Angiotensin II; Animals; Captopril; Dehydration; Deoxyglucose; Disease Models, Animal; Glucose; Infusions, Parenteral; Injections, Intravenous; Male; Neurosecretory Systems; Rats; Rats, Brattleboro; Rats, Inbred Strains; Subfornical Organ; Time Factors | 1985 |