Page last updated: 2024-08-23

captopril and Alloxan Diabetes

captopril has been researched along with Alloxan Diabetes in 98 studies

Research

Studies (98)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (8.16)	18.7374
1990's	32 (32.65)	18.2507
2000's	36 (36.73)	29.6817
2010's	16 (16.33)	24.3611
2020's	6 (6.12)	2.80

Authors

Authors	Studies
Chen, K; Gao, X; Hu, C; Jiang, Z; Liu, K	1
Alizadeh-Fanalou, S; Chamani, E; Ebadi, Z; Fadaei, R; Fallah, S; Ghaffari, T; Moradi, N; Yarahmadi, S	1
Carvalho, VF; Chaves, ADS; Insuela, DBR; Magalhães, NS; Martins, MA; Silva, PMRE	1
Balochnejadmojarrad, T; Chamani, E; Ebadi, Z; Fadaei, R; Fallah, S; Kazemi Fard, T; Moradi, N	1
Jesson, MI; Nikolic-Paterson, DJ; Pullen, N; Schlerman, FJ; Tesch, GH	1
Abd El-Latif, HA; El-Yamany, MF; Georgy, GS; Youssef, MM	1
Abo-Saif, AA; Kozman, MR; Messiha, BAS; Mizar, SMM	1
Chu, S; Li, H; Liu, D; Liu, X; Qu, X; Shuai, Y; Zhang, X; Zhao, H	1
Abadir, P; Ansari, A; Berger, A; Beselman, A; Budman, J; Faghih, M; Fedarko, N; Harmon, J; Hosseini, S; Inagami, T; Keenahan, K; Lay, F; Marti, G; Rini, D; Smith, B; Tian, J; Vuong, D; Walston, J	1
Dong, LY; Jin, KK; Qiu, XX; Yao, LP; Zhao, J	1
Mohebbati, R; Niazmand, S; Paseban, M; Sahebkar, A; Sathyapalan, T	1
Chen, X; Diao, TY; Gu, SS; Pan, H; Wong, MS; Zhang, FY; Zhang, Y	1
Akhtar, S; Al-Rashdan, I; Babiker, F; Benter, IF; Yousif, M	1
Awad, AS; Cooper, TK; Gao, T; Gvritishvili, A; Tombran-Tink, J; You, H	1
Abd Allah, ES; Gomaa, AM	1
Davis, G; Harrison, JC; Sammut, IA; Walker, RJ; Yao, Y	1
Jakovljevic, VL; Nikolic, T; Ristic, D; Ristic, P; Srejovic, I; Stojic, I; Zivkovic, V	1
Li, XL; Sha, NN; Shi, Q; Shu, B; Wang, XL; Wang, YJ; Wong, MS; Xiao, HH; Zhang, Y; Zhao, YJ	1
Ku, SK; Lee, HS	1
Lu, J; Sun, L; Yu, XJ; Zang, WJ; Zhang, CH	1
Al-Maghrebi, M; Benter, IF; Diz, DI	1
Bogdanski, P; Czaplicka, E; Jablecka, A; Krauss, H; Olszewski, J; Smolarek, I	1
Chaves, MM; Chianca-Júnior, D; Costa, DC; Granato de Faria, K; Lima, WG; Pádua, Bda C; Pedrosa, ML; Rodrigues de Araujo, G; Rossoni, JV; Silva, ME; Souza, AA	1
Chu, L; Guan, SJ; Guo, QY; Ji, ES; Liang, F; Ma, ZH; Wang, JY; Weiss, JW; Wu, YL; Zhang, JP	1
Akhtar, S; Benter, IF; Dhaunsi, GS; Makki, BM; Qabazard, BA; Yousif, MH	1
Al-Mulhim, AS; Fouad, AA; Jresat, I; Morsy, MA	1
Allen, TJ; Burrell, LM; Cao, Z; Cooper, ME; Davis, BJ; Lassila, M	1
Akalin, S; Akoğlu, E; Ersöz, O; Haklar, G; Küçükkaya, B; Yavuz, D	1
Gao, L; Kern, TS; Widness, M; Xi, X; Zhang, JZ	1
Abiko, A; Abiko, T; Bursell, SE; Clermont, AC; Feener, EP; Horio, N; Shoelson, BD	1
Kanaki, T; Matsuda, M; Naitoh, T; Tsuruzoe, N; Yotsumoto, T	1
Ekberg, K; Isaksson, B; Jacobson, SH; Johansson, BL; Samnegård, B; Sjöquist, M; Wahren, J	1
Ghini, B; Lehfeld, LS; Lopes de Faria, JB; Silveira, LA	1
Chen, G; Huang, HB; Li, LT; Liang, JX; Lin, LX; Lin, M; Lin, QM; Wen, JP; Yao, J; Zhang, FL; Zhuang, WT	1
Xie, XW; Zhao, P	1
Leehey, DJ; Singh, AK; Singh, R	1
Godes, M; Hocher, B; Neumayer, HH; Richter, CM; Simon, K; Thöne-Reinke, C; Thormählen, D	1
Ibrahim, MA; Kanzaki, T; Satoh, N; Ueda, S; Yamagata, S	1
Cool, DR; Elased, KM; Morris, M	1
Amazonas, RB; Lopes de Faria, JB	1
Danser, AH; Krop, M; van Esch, JH	1
Bell, TD; Brands, MW; Fleming, C; Janardhanan, R; Rojas, M; Springfield, V; Sturgis, LC	1
Cai, H; Oak, JH	1
Arikawa, E; Harris, RA; He, Z; Isshiki, K; King, GL; Luptak, I; Ma, RC; Maeno, Y; Patti, ME; Tian, R; Weir, GC; Yasuda, Y; Zammit, VA	1
Gao, YY; Lu, Q; Pan, YM; Wang, JY; Yin, XX	1
Akyuz, F; Temel, HE	1
Gao, L; Kern, TS; Xi, X; Zhang, JZ	1
Huang, Z; Jansson, L; Sjöholm, A	1
Abe, K; Fu, LP; Kanazawa, M; Kohzuki, M; Obara, K; Saito, T; Yasujima, M; Yoshida, K	1
Barbee, RW; Conrad, K; Maymind, M; Zimmerman, R	1
Nickels, D; Poth, M; Schwab, N	1
Abe, K; Hiwatari, M; Kanazawa, M; Kohzuki, M; Omata, K; Sato, T; Watanabe, H; Yasujima, M; Yoshida, K	1
Chen, GY; Chen, LH	1
Cosio, FG; Hajinazarian, M; Mahan, JD; Nahman, NS	1
Liu, Z	1
Kato, Y; Nara, Y; Sato, T; Yamori, Y	1
Candy, G; Norton, GR; Woodiwiss, AJ	1
Bensaoula, T; Ottlecz, A	2
Abe, K; Kanazawa, M; Kohzuki, M; Yasujima, M; Yoshida, K	1
Geng, J; Lu, J; Pan, C	1
Chakir, M; D'Orléans-Juste, P; Plante, GE	1
Cazes, M; Cloarec, A; García-Robles, R; Rábano, A; Ruilope, LM; Villa, E	1
Abe, K; Kanazawa, M; Kohzuki, M; Liu, PF; Obara, K; Saito, T; Sato, T; Yasujima, M; Yoshida, K	1
Fukui, M; Shou, I; Tang, Z; Tomino, Y; Wang, LN	1
Bartoli, E; Griffin, CA; Schambelan, M; Sechi, LA; Valentin, JP; Zingaro, L	1
Naitoh, T; Shikada, K; Tanaka, S; Yotsumoto, T	1
Beyer, KH; Follansbee, MH; Griffith, JW; Vesell, ES	1
Beyer, KH; Follansbee, MH; Vesell, ES	1
Flyvbjerg, A; Grønbaek, H; Lancranjan, I; Orskov, H; Osterby, R; Vogel, I	1
Kedziora-Kornatowska, K; Luciak, M	1
Allen, TJ; Burrell, LM; Cooper, ME; Johnston, CI; Rockell, MD; Tikkanen, I; Tikkanen, T	1
Ahiskali, R; Akalin, S; Budak, Y; Ekicioglu, G; Emerk, K; Ersöz, O; Kuçükkaya, B; Yavuz, DG	1
Yoshikawa, H	1
Kamata, K; Mizutani, K	1
Amiri, F; Garcia, R	1
Katoh, M; Kurosawa, Y; Narita, H; Ohmachi, Y; Tanaka, N; Yoneda, H	1
Arbin, V; Claperon, N; Fournié-Zaluski, MC; Peyroux, J; Roques, BP	1
Kedziora-Kornatowska, KZ; Luciak, M; Paszkowski, J	1
Fukui, M; Shou, I; Tomino, Y	1
Al-Shafei, AI; Bronns, G; Carpenter, TA; Gresham, GA; Hall, LD; Huang, CL; Wise, RG	1
Al-Shafei, AI; Carpenter, TA; Gresham, GA; Hall, LD; Huang, CL; Wise, RG	1
Isogai, S; Mogami, K; Ouchi, H; Yoshino, G	1
Kesavarao, U; Sharma, JN	1
Ha, H; Kim, KH	1
Cho, C; Katz, A; Silverman, M; Whiteside, C	1
Fujishima, M; Iwase, M; Nakao, Y; Sadoshima, S; Takata, Y; Takishita, S; Tomita, Y; Tsuchihashi, T; Yamashita, Y	1
Goldfarb, S; Kern, EF; Simmons, DA; Ziyadeh, FN	1
Reddi, AS	1
Gottardo, G; Malendowicz, LK; Mazzocchi, G; Nussdorfer, GG; Rebuffat, P	1
Belloni, AS; Gottardo, G; Malendowicz, LK; Mazzocchi, G; Nussdorfer, GG; Rebuffat, P	1
Dietze, G; Fink, E; Jauch, KW; Mehnert, H; Rett, K; Wicklmayr, M	1
Ashford, A; Bailey, GS; Jaffa, AA; Pratt, J	1
Akabane, S; Ito, K; Kawamura, M; Kojima, S; Matsushima, Y	1
Bennett, T; Gardiner, SM; Hebden, RA	3
Ramos, OL	1

Reviews

2 review(s) available for captopril and Alloxan Diabetes

Article	Year
Efficacy of ACE inhibitor (captopril) on glomerular antioxidant enzyme activity and hypertension in diabetic hypertensive rats. Contributions to nephrology, 2001, Issue:134 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypertension; Kidney Glomerulus; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY	2001
An impairment of barrier size and charge selectivity of glomerular basement membrane in streptozotocin-induced diabetes and prevention by pharmacological therapy. Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan, 2000, Volume: 33, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anions; Basement Membrane; Captopril; Diabetes Mellitus, Experimental; Kidney Glomerulus; Male; Microscopy, Electron; Rats; Rats, Wistar; Streptozocin	2000

Article

Year

Efficacy of ACE inhibitor (captopril) on glomerular antioxidant enzyme activity and hypertension in diabetic hypertensive rats.

Contributions to nephrology, 2001, Issue:134

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypertension; Kidney Glomerulus; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2001

An impairment of barrier size and charge selectivity of glomerular basement membrane in streptozotocin-induced diabetes and prevention by pharmacological therapy.

Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan, 2000, Volume: 33, Issue:3

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anions; Basement Membrane; Captopril; Diabetes Mellitus, Experimental; Kidney Glomerulus; Male; Microscopy, Electron; Rats; Rats, Wistar; Streptozocin

2000

Other Studies

96 other study(ies) available for captopril and Alloxan Diabetes

Article	Year
Captopril alleviates oxidative damage in diabetic retinopathy. Life sciences, 2022, Feb-01, Volume: 290 Topics: Animals; Captopril; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Endothelial Cells; Glucose; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retina; Retinal Vessels; Streptozocin; Tyrosine; Vascular Endothelial Growth Factor A	2022
Captopril and Spironolactone can Attenuate Diabetic Nephropathy in Wistar Rats by Targeting ABCA1 and microRNA-33. Current pharmaceutical design, 2022, Volume: 28, Issue:16 Topics: Animals; ATP Binding Cassette Transporter 1; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; MicroRNAs; Rats; Rats, Wistar; Spironolactone	2022
Effect of the renin-angiotensin system on the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic mice: Role of angiotensin-II type 2 receptor. Frontiers in endocrinology, 2022, Volume: 13 Topics: Alloxan; Animals; Captopril; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucocorticoids; Mice; Renin-Angiotensin System	2022
Captopril and Spironolactone Can Attenuate Diabetic Nephropathy in Wistar Rats by Targeting microRNA-192 and microRNA-29a/b/c. DNA and cell biology, 2019, Volume: 38, Issue:10 Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Urea Nitrogen; Captopril; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diuretics; Drug Combinations; Drug Repositioning; Gene Expression Regulation; Hyperglycemia; Hypoglycemic Agents; Male; MicroRNAs; Rats; Rats, Wistar; Spironolactone; Streptozocin; Transforming Growth Factor beta; Treatment Outcome	2019
Combined inhibition of CCR2 and ACE provides added protection against progression of diabetic nephropathy in American journal of physiology. Renal physiology, 2019, 12-01, Volume: 317, Issue:6 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Azabicyclo Compounds; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Hypertension, Renal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Podocytes; Pyrimidines; Receptors, CCR2	2019
Aliskiren and captopril improve cognitive deficits in poorly controlled STZ-induced diabetic rats via amelioration of the hippocampal P-ERK, GSK3β, P-GSK3β pathway. Toxicology and applied pharmacology, 2020, 05-01, Volume: 394 Topics: Amides; Animals; Avoidance Learning; Brain; Captopril; Cholinesterases; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Fumarates; Glycogen Synthase Kinase 3; Hippocampus; Interleukin-1beta; Male; MAP Kinase Signaling System; Maze Learning; Pancreas; Rats; Rats, Sprague-Dawley; Recognition, Psychology	2020
Combination of Captopril with Gliclazide Decreases Vascular and Renal Complications and Improves Glycemic Control in Rats with Streptozotocin- Induced Diabetes Mellitus. Endocrine, metabolic & immune disorders drug targets, 2021, Volume: 21, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Gliclazide; Glycemic Control; Hypoglycemic Agents; Kidney; Male; Rats; Rats, Wistar; Streptozocin	2021
Effects of HuoxueJiangtang decoction alone or in combination with metformin on renal function and renal cortical mRNA expression in diabetic nephropathy rats. Pharmaceutical biology, 2020, Volume: 58, Issue:1 Topics: Animals; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Drugs, Chinese Herbal; Hypoglycemic Agents; Male; Metformin; Rats; Rats, Wistar; RNA, Messenger; Streptozocin	2020
Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds. The Journal of investigative dermatology, 2018, Volume: 138, Issue:2 Topics: Administration, Cutaneous; Alloxan; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chronic Disease; Diabetes Mellitus, Experimental; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Skin; Swine; Swine, Miniature; Time Factors; Treatment Outcome; Valsartan; Wound Healing; Wounds and Injuries	2018
Captopril inhibits calpain‑mediated apoptosis of myocardial cells in diabetic rats and improves cardiac function. Molecular medicine reports, 2018, Volume: 18, Issue:2 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calpain; Captopril; Caspase 3; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Heart; Humans; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Ventricular Dysfunction, Left	2018
Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus. Biomolecules, 2019, 03-27, Volume: 9, Issue:4 Topics: Animals; Aspirin; Atorvastatin; Captopril; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Metformin; Neuroprotective Agents; Rats; Rats, Wistar; Streptozocin	2019
Effects of angiotensin-converting enzyme inhibitor, captopril, on bone of mice with streptozotocin-induced type 1 diabetes. Journal of bone and mineral metabolism, 2014, Volume: 32, Issue:3 Topics: Acid Phosphatase; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Isoenzymes; Male; Mice; Mice, Inbred DBA; NF-kappa B; Osteocalcin; Osteoclasts; Random Allocation; Renin; Renin-Angiotensin System; RNA, Messenger; Streptozocin; Tartrate-Resistant Acid Phosphatase; Tibia; Transforming Growth Factor beta; Up-Regulation	2014
RU28318, an aldosterone antagonist, in combination with an ACE inhibitor and angiotensin receptor blocker attenuates cardiac dysfunction in diabetes. Journal of diabetes research, 2013, Volume: 2013 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Heart; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Spironolactone	2013
Delayed Treatment with a Small Pigment Epithelium Derived Factor (PEDF) Peptide Prevents the Progression of Diabetic Renal Injury. PloS one, 2015, Volume: 10, Issue:7 Topics: Animals; Blood Pressure; Captopril; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Eye Proteins; Kidney; Macrophages; Male; Membrane Proteins; Mice; Nerve Growth Factors; Serpins	2015
Effects of curcumin and captopril on the functions of kidney and nerve in streptozotocin-induced diabetic rats: role of angiotensin converting enzyme 1. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2015, Volume: 40, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Captopril; Creatinine; Curcumin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Inflammation; Kidney; Lipids; Male; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Wistar	2015
Renal functional responses in diabetic nephropathy following chronic bilateral renal denervation. Autonomic neuroscience : basic & clinical, 2017, Volume: 204 Topics: Animals; Blood Pressure; Captopril; Denervation; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Heart Rate; Kidney; Natriuretic Agents; Random Allocation; Rats, Transgenic; Renal Circulation; Renin-Angiotensin System; Sympathetic Nervous System	2017
The effects of zofenopril on cardiac function and pro-oxidative parameters in the streptozotocin-induced diabetic rat heart. Molecular and cellular biochemistry, 2017, Volume: 426, Issue:1-2 Topics: Animals; Biomarkers; Captopril; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Male; Oxidative Stress; Rats; Rats, Wistar	2017
Differential response of bone and kidney to ACEI in db/db mice: A potential effect of captopril on accelerating bone loss. Bone, 2017, Volume: 97 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Bone and Bones; Bone Resorption; Calcium; Captopril; Diabetes Mellitus, Experimental; Femur; Fibrosis; Kidney; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Renin-Angiotensin System; RNA, Messenger; Tibia; Vitamin D3 24-Hydroxylase; X-Ray Microtomography	2017
Effect of Picrorrhiza rhizoma extracts on early diabetic nephropathy in streptozotocin-induced diabetic rats. Journal of medicinal food, 2008, Volume: 11, Issue:2 Topics: Animals; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Hypoglycemic Agents; Kidney; Organ Size; Phytotherapy; Picrorhiza; Plant Extracts; Rats; Rats, Sprague-Dawley	2008
Ameliorative effect of Captopril and Valsartan on an animal model of diabetic cardiomyopathy. Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:11 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomyopathies; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Female; Isoenzymes; L-Lactate Dehydrogenase; Male; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2008
Endogenous angiotensin-(1-7) reduces cardiac ischemia-induced dysfunction in diabetic hypertensive rats. Pharmacological research, 2009, Volume: 59, Issue:4 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Heart; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Nuclear Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger; Signal Transduction	2009
Influence of selected angiotensin-converting enzyme inhibitors on alloxan-induced diabetic cataract in rabbits. Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:11 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Captopril; Cataract; Diabetes Mellitus, Experimental; Enalapril; Rabbits	2009
Effect of captopril and the bradykinin-PKC pathway on ROS production in type 1 diabetic rats. Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:12 Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Insulin; Myocardium; Neutrophils; Oxidative Stress; Protein Kinase C; Rats, Inbred F344; Reactive Oxygen Species; Signal Transduction	2011
Long-term administration of fasudil improves cardiomyopathy in streptozotocin-induced diabetic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:6 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Apoptosis; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Enzyme Inhibitors; Hemodynamics; In Situ Nick-End Labeling; Male; Malondialdehyde; Microscopy, Electron, Transmission; Myocardium; Organ Size; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Superoxide Dismutase	2012
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes. Pharmacological research, 2012, Volume: 66, Issue:3 Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury	2012
Protective effects of captopril in diabetic rats exposed to ischemia/reperfusion renal injury. The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:2 Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Caspase 3; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fas Ligand Protein; Glutathione; Heme Oxygenase (Decyclizing); Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Kidney; Kidney Diseases; Male; Malondialdehyde; Microtubule-Associated Proteins; NF-kappa B; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survivin; Tumor Necrosis Factor-alpha	2013
Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system. Clinical science (London, England : 1979), 2003, Volume: 104, Issue:4 Topics: Alanine; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Captopril; Cardiomegaly; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Enzyme Inhibitors; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Neprilysin; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2003
Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney. Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 69, Issue:4 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Kidney; Lipid Peroxidation; Losartan; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar	2003
Captopril inhibits glucose accumulation in retinal cells in diabetes. Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:9 Topics: Adrenergic beta-Antagonists; Aldehyde Reductase; Angiotensin-Converting Enzyme Inhibitors; Animals; Atenolol; Blood Glucose; Blotting, Western; Captopril; Cattle; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium, Vascular; Glucose; Glucose Transporter Type 1; Lisinopril; Male; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels	2003
Angiotensin AT(1) receptor antagonism normalizes retinal blood flow and acetylcholine-induced vasodilatation in normotensive diabetic rats. Diabetologia, 2004, Volume: 47, Issue:1 Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Fluorescein Angiography; Hemodynamics; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Retinal Vessels; Tetrazoles; Vasodilation	2004
A novel peroxisome proliferator-activated receptor (PPAR)gamma agonist, NIP-222, reduces urinary albumin excretion in streptozotocin-diabetic mice independent of PPARgamma activation. Metabolism: clinical and experimental, 2003, Volume: 52, Issue:12 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Body Weight; Captopril; Chromans; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Genes, Reporter; Hypoglycemic Agents; Kidney; Luciferases; Male; Mice; Organ Size; Plasmids; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors; Troglitazone; Urodynamics	2003
C-peptide and captopril are equally effective in lowering glomerular hyperfiltration in diabetic rats. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; C-Peptide; Captopril; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow	2004
Early blood pressure normalization independent of the class of antihypertensive agent prevents augmented renal fibronectin and albuminuria in experimental diabetic nephropathy. Kidney & blood pressure research, 2004, Volume: 27, Issue:2 Topics: Albuminuria; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Synergism; Fibronectins; Glomerular Filtration Rate; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Verapamil	2004
[Effects of captopril on myocardial tissue energy metabolism and inflammation in rats with diabetic cardiomyopathy]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2004, Volume: 24, Issue:7 Topics: Animals; Captopril; Cardiomyopathies; Diabetes Mellitus, Experimental; Energy Metabolism; Male; Myocardium; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley	2004
[The experimental study of captopril and valsartan on the preventing and treatment of diabetic retinopathy in diabetic mice]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2004, Volume: 40, Issue:11 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Mice; Random Allocation; Tetrazoles; Valine; Valsartan; Vascular Endothelial Growth Factor A	2004
A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli. American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:6 Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney Glomerulus; Male; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley	2005
Inhibition of both neutral endopeptidase and endothelin-converting enzyme by SLV306 reduces proteinuria and urinary albumin excretion in diabetic rats. Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1 Topics: Administration, Oral; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Benzazepines; Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelin-Converting Enzymes; Fibrosis; Kidney; Metalloendopeptidases; Neprilysin; Protease Inhibitors; Proteinuria; Rats; Rats, Wistar; Time Factors	2004
Effect of diabetes on aortic nitric oxide synthesis in spontaneously hypertensive rats; does captopril modulate this effect? Life sciences, 2005, Jul-15, Volume: 77, Issue:9 Topics: Animals; Aorta; Captopril; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Inbred SHR	2005
Novel mass spectrometric methods for evaluation of plasma angiotensin converting enzyme 1 and renin activity. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Chelating Agents; Diabetes Mellitus, Experimental; Edetic Acid; Male; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Phenanthrolines; Receptor, Angiotensin, Type 1; Renin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2005
Effects of tight blood pressure control on glomerular hypertrophy in a model of genetic hypertension and experimental diabetes mellitus. Life sciences, 2006, Oct-26, Volume: 79, Issue:22 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Hypertension; Immunohistochemistry; Kidney Glomerulus; Rats; Rats, Inbred SHR	2006
Letter by Krop et al regarding article, "Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium". Circulation, 2006, Oct-24, Volume: 114, Issue:17 Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Buffers; Captopril; Diabetes Complications; Diabetes Mellitus, Experimental; Diffusion; Free Radical Scavengers; Imidazoles; Kallikreins; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Perfusion; Rats; Renin-Angiotensin System; Ribosomal Protein S6 Kinases, 90-kDa; Species Specificity; Tetrazoles	2006
Blood pressure early in diabetes depends on a balance between glomerular filtration rate and the renin-angiotensin system. American journal of hypertension, 2006, Volume: 19, Issue:12 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium; Time Factors	2006
Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice. Diabetes, 2007, Volume: 56, Issue:1 Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Hydrogen Peroxide; Hyperglycemia; Mice; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Signal Transduction; Superoxides; Tetrazoles; Vasodilation	2007
Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats. Diabetes, 2007, Volume: 56, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Captopril; Cell Membrane; Diabetes Mellitus, Experimental; Drug Implants; Gene Expression Regulation; Heart; Insulin; Islets of Langerhans Transplantation; Male; Myocardium; Oligonucleotide Array Sequence Analysis; Peroxisome Proliferator-Activated Receptors; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Inbred Lew; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA	2007
Effects of Ginkgo biloba on prevention of development of experimental diabetic nephropathy in rats. Acta pharmacologica Sinica, 2007, Volume: 28, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Blood Glucose; Captopril; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Ginkgo biloba; Kidney; Male; Matrix Metalloproteinase 2; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1	2007
The effects of captopril and losartan on erythrocyte membrane Na+/K(+)-ATPase activity in experimental diabetes mellitus. Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Losartan; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	2007
Captopril inhibits capillary degeneration in the early stages of diabetic retinopathy. Current eye research, 2007, Volume: 32, Issue:10 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Capillaries; Captopril; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Hyperglycemia; Leukostasis; Losartan; Male; Rats; Rats, Inbred Lew; Retina; Retinal Vessels; Vascular Cell Adhesion Molecule-1	2007
Gender-specific regulation of pancreatic islet blood flow, insulin levels and glycaemia in spontaneously diabetic Goto-Kakizaki rats. Clinical science (London, England : 1979), 2008, Volume: 115, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Irbesartan; Islets of Langerhans; Male; Pravastatin; Rats; Rats, Mutant Strains; Regional Blood Flow; Sex Factors; Tetrazoles	2008
Antihypertensive and renal-protective effects of losartan in streptozotocin diabetic rats. Journal of hypertension, 1995, Volume: 13, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glomerulosclerosis, Focal Segmental; Hypertension; Imidazoles; Kidney; Losartan; Male; Organ Size; Random Allocation; Rats; Rats, Inbred SHR; Tetrazoles	1995
Effect of verapamil and captopril on endothelial injury in the diabetic hypertensive rat. American journal of hypertension, 1994, Volume: 7, Issue:7 Pt 1 Topics: Animals; Blood Pressure; Blood Vessels; Body Weight; Captopril; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypertension; Male; Myocardium; Rats; Rats, Wistar; Tunica Media; Verapamil	1994
Effects of somatostatin and captopril on glomerular prostaglandin E2 production in normal and diabetic rats. Prostaglandins, 1993, Volume: 46, Issue:1 Topics: Animals; Captopril; Diabetes Mellitus, Experimental; Dinoprostone; In Vitro Techniques; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Somatostatin	1993
Urinary active kallikrein excretion and diabetic renal impairments in streptozotocin-treated rats. The Tohoku journal of experimental medicine, 1993, Volume: 171, Issue:2 Topics: Animals; Captopril; Diabetes Mellitus, Experimental; Kallikreins; Kidney; Male; Proteinuria; Rats; Rats, Inbred WKY; Streptozocin	1993
[Effects of captopril on myocardial ultrastructure in diabetic rats]. Zhonghua xin xue guan bing za zhi, 1993, Volume: 21, Issue:1 Topics: Animals; Captopril; Diabetes Mellitus, Experimental; Female; Heart; Insulin; Mitochondria, Heart; Myocardium; Rats; Rats, Sprague-Dawley	1993
Angiotensin-converting enzyme inhibition partially prevents diabetic organomegaly. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1994, Volume: 23, Issue:1 Topics: Analysis of Variance; Animals; Captopril; Cardiomegaly; Diabetes Mellitus, Experimental; Female; Fibronectins; Hepatomegaly; Hypertrophy; Kidney; Organ Size; Rats; Rats, Sprague-Dawley	1994
[Renal structure and function in experimental diabetic rats following unilateral nephrectomy]. Zhonghua yi xue za zhi, 1993, Volume: 73, Issue:9 Topics: Animals; Captopril; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Insulin; Kidney; Male; Nephrectomy; Rats; Rats, Wistar	1993
Effect of antihypertensive treatment with alacepril on insulin resistance in diabetic spontaneously hypertensive rats. Metabolism: clinical and experimental, 1996, Volume: 45, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cholesterol, HDL; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypertension; Insulin; Insulin Resistance; Male; Rats; Rats, Inbred SHR; Streptozocin; Triglycerides	1996
Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats. Circulation, 1996, May-15, Volume: 93, Issue:10 Topics: Animals; Blood Pressure; Captopril; Collagen; Diabetes Mellitus, Experimental; Diastole; Guanidines; Male; Organ Size; Rats; Rats, Sprague-Dawley; Streptozocin; Ventricular Function, Left	1996
Captopril ameliorates the decreased Na+,K(+)-ATPase activity in the retina of streptozotocin-induced diabetic rats. Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Enzyme Inhibitors; Isoenzymes; Male; Ouabain; Peptidyl-Dipeptidase A; Random Allocation; Rats; Retina; Sodium-Potassium-Exchanging ATPase; Streptozocin	1996
Effects of benidipine, a calcium antagonist, on urinary kallikrein excretion and renal impairment in experimental diabetes. Journal of hypertension, 1996, Volume: 14, Issue:2 Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Diabetes Mellitus, Experimental; Dihydropyridines; Kallikreins; Male; Proteinuria; Radioimmunoassay; Rats; Rats, Inbred WKY; Streptozocin	1996
[Effects of insulin and captopril on growth of glomerular mesangial cells in STZ-induced diabetic rats]. Zhonghua yi xue za zhi, 1996, Volume: 76, Issue:1 Topics: Animals; Captopril; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Glomerular Mesangium; Hypoglycemic Agents; Insulin; Interleukin-6; Male; Rats; Rats, Wistar; Streptozocin; Tumor Necrosis Factor-alpha	1996
Neutral endopeptidase inhibition, a new approach in the exploration of diabetic vasculopathy in rats. European journal of pharmacology, 1995, Oct-04, Volume: 285, Issue:1 Topics: Alanine; Animals; Blood Pressure; Capillary Permeability; Captopril; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Female; Glycopeptides; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Streptozocin; Thiorphan	1995
Effects of UP269-6, a new angiotensin II receptor antagonist, and captopril on the progression of rat diabetic nephropathy. American journal of hypertension, 1997, Volume: 10, Issue:3 Topics: Albuminuria; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Captopril; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Kidney; Nephrectomy; Pyrimidines; Rats; Rats, Wistar; Tetrazoles	1997
Cardiovascular and renal protective effects of losartan in spontaneously hypertensive rats with diabetes mellitus. Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Hemodynamics; Hypertension; Imidazoles; Kidney Diseases; Losartan; Male; Nephrectomy; Rats; Rats, Inbred SHR; Tetrazoles	1995
Effects of antihypertensive drugs or glycemic control on antioxidant enzyme activities in spontaneously hypertensive rats with diabetes. Nephron, 1997, Volume: 76, Issue:3 Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Captopril; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Glutathione Peroxidase; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Superoxide Dismutase	1997
Effects of angiotensin II on insulin receptor binding and mRNA levels in normal and diabetic rats. Diabetologia, 1997, Volume: 40, Issue:7 Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Insulin; Kidney; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Reference Values; Renin; RNA, Messenger; RNA, Ribosomal, 28S; Transcription, Genetic	1997
Effects of specific antagonists of angiotensin II receptors and captopril on diabetic nephropathy in mice. Japanese journal of pharmacology, 1997, Volume: 75, Issue:1 Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertrophy; Imidazoles; Kidney Diseases; Losartan; Male; Mice; Mice, Inbred Strains; Pyridines; Receptors, Angiotensin; Streptozocin	1997
Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats. Pharmacology, 1997, Volume: 54, Issue:5 Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Guanidines; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Kidney; Kidney Function Tests; Male; Molecular Weight; Pyrazines; Rats; Rats, Sprague-Dawley; Serum Albumin; Streptozocin	1997
Studies on pyrazinoylguanidine. 6. Prevention of cataracts in STZ-diabetic rats. Pharmacology, 1997, Volume: 54, Issue:5 Topics: Animals; Antihypertensive Agents; Captopril; Cataract; Diabetes Mellitus, Experimental; Guanidines; Hypoglycemic Agents; Male; Odds Ratio; Pyrazines; Rats; Rats, Sprague-Dawley; Streptozocin	1997
Effect of octreotide, captopril or insulin on renal changes and UAE in long-term experimental diabetes. Kidney international, 1998, Volume: 53, Issue:1 Topics: Albuminuria; Animals; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Eating; Female; Insulin; Insulin-Like Growth Factor I; Kidney; Octreotide; Organ Size; Rats; Rats, Wistar; Streptozocin	1998
Effect of angiotensin convertase inhibitors on lipid peroxidation and peroxyl radical-trapping capacity in rats with experimental diabetes. Biochemistry and molecular biology international, 1998, Volume: 45, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Enalapril; Erythrocytes; Free Radicals; Lipid Peroxidation; Male; Malondialdehyde; Peroxides; Rats; Rats, Wistar	1998
Dual inhibition of neutral endopeptidase and angiotensin-converting enzyme in rats with hypertension and diabetes mellitus. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:4 Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hypertension; Male; Methionine; Neprilysin; Propionates; Rats; Rats, Inbred SHR; Renal Circulation; Renin; Sulfhydryl Compounds	1998
The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model. Journal of hypertension, 1999, Volume: 17, Issue:8 Topics: Albuminuria; Angiotensin Receptor Antagonists; Animals; Anions; Antihypertensive Agents; Captopril; Cell Membrane; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Mesangium; Glycosaminoglycans; Losartan; Rats; Rats, Wistar; Sialic Acids; Streptozocin	1999
[Renal angiotensin converting enzyme (ACE) expression in diabetic rats: the effect of ACE inhibitors]. Nihon Jinzo Gakkai shi, 1999, Volume: 41, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; RNA, Messenger; Thiazepines	1999
Changes in angiotensin converting enzyme activity in the renal vascular bed of streptozotocin-induced diabetic rat. Research communications in molecular pathology and pharmacology, 1999, Volume: 104, Issue:2 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Drug Interactions; Kidney; Losartan; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renal Artery; Streptozocin; Vasoconstriction	1999
Renal angiotensin II receptors and protein kinase C in diabetic rats: effects of insulin and ACE inhibition. American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Captopril; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Isoenzymes; Kidney Glomerulus; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin	2000
Effects of imidapril and captopril on streptozotocin-induced diabetic nephropathy in mice. European journal of pharmacology, 2000, Jun-23, Volume: 398, Issue:3 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibiotics, Antineoplastic; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Imidazoles; Imidazolidines; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Renal Artery; Streptozocin	2000
Effects of combined neutral endopeptidase 24-11 and angiotensin-converting enzyme inhibition on femoral vascular conductance in streptozotocin-induced diabetic rats. British journal of pharmacology, 2000, Volume: 130, Issue:6 Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Femoral Artery; Hemodynamics; Kininogens; Lysine Carboxypeptidase; Male; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Thiorphan; Time Factors	2000
Lipid peroxidation and activities of antioxidant enzymes in the diabetic kidney: effect of treatment with angiotensin convertase inhibitors. IUBMB life, 2000, Volume: 49, Issue:4 Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Captopril; Catalase; Diabetes Mellitus, Experimental; Enalapril; Hemoglobin A; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors	2000
Biochemical and ultrastructural studies in the neural retina and retinal pigment epithelium of STZ-diabetic rats: effect of captopril. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2001, Volume: 17, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Peptidyl-Dipeptidase A; Pigment Epithelium of Eye; Rats; Rats, Long-Evans; Retina; Sodium-Potassium-Exchanging ATPase	2001
Non-invasive magnetic resonance imaging assessment of myocardial changes and the effects of angiotensin-converting enzyme inhibition in diabetic rats. The Journal of physiology, 2002, Jan-15, Volume: 538, Issue:Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Heart; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Magnetic Resonance Imaging, Cine; Male; Myocardium; Organ Size; Rats; Rats, Wistar	2002
Magnetic resonance imaging analysis of cardiac cycle events in diabetic rats: the effect of angiotensin-converting enzyme inhibition. The Journal of physiology, 2002, Jan-15, Volume: 538, Issue:Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Circulation; Diabetes Mellitus, Experimental; Heart; Magnetic Resonance Imaging, Cine; Male; Myocardial Contraction; Rats; Rats, Wistar; Stroke Volume; Ventricular Function, Left	2002
Effect of captopril on urinary kallikrein, blood pressure and myocardial hypertrophy in diabetic spontaneously hypertensive rats. Pharmacology, 2002, Volume: 64, Issue:4 Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Kallikreins; Male; Rats; Rats, Inbred SHR	2002
Amelioration of diabetic microalbuminuria and lipid peroxidation by captopril. Yonsei medical journal, 1992, Volume: 33, Issue:3 Topics: Albuminuria; Animals; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Insulin; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley	1992
Diabetic glomerulopathy following unilateral nephrectomy in the dog. Clinical and investigative medicine. Medecine clinique et experimentale, 1990, Volume: 13, Issue:5 Topics: Albuminuria; Animals; Anions; Basement Membrane; Capillary Permeability; Captopril; Dextrans; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dogs; Glomerular Filtration Rate; Glomerular Mesangium; Hypertrophy; Indicator Dilution Techniques; Inulin; Kidney; Male; Microscopy, Electron; Nephrectomy; Organ Size; Pancreatectomy; Renin	1990
Suppression of the renin-angiotensin system induced by streptozotocin treatment in neonatal spontaneously hypertensive rats. Japanese circulation journal, 1990, Volume: 54, Issue:2 Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin-Angiotensin System; Streptozocin	1990
Effects of polyol-pathway inhibition and dietary myo-inositol on glomerular hemodynamic function in experimental diabetes mellitus in rats. Diabetes, 1991, Volume: 40, Issue:4 Topics: Animals; Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Diet; Dietary Proteins; Glomerular Filtration Rate; Imidazoles; Imidazolidines; Inositol; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Sugar Alcohols	1991
Prevention of albuminuria by captopril in diabetic rats. General pharmacology, 1991, Volume: 22, Issue:2 Topics: Albuminuria; Animals; Blood Glucose; Blood Pressure; Captopril; Chromatography, Ion Exchange; Diabetes Mellitus, Experimental; Glycosaminoglycans; Heparin; In Vitro Techniques; Kidney Glomerulus; Male; Potassium; Rats; Rats, Inbred Strains; Sulfates; Sulfur Radioisotopes	1991
Streptozotocin-induced experimental diabetes causes a time-dependent inhibition of growth and steroidogenic capacity of rat adrenal zona glomerulosa. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1990, Volume: 190, Issue:1 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Captopril; Cell Nucleus; Dexamethasone; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Kinetics; Male; Mitochondria; Rats; Rats, Inbred Strains; Zona Glomerulosa	1990
Zona glomerulosa morphology and function in streptozotocin-induced diabetic rats. Endocrinology, 1988, Volume: 123, Issue:2 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Blood Glucose; Captopril; Dexamethasone; Diabetes Mellitus, Experimental; Endothelium; Male; Microscopy, Electron; Mitochondria; Potassium; Rats; Rats, Inbred Strains; Renin	1988
Angiotensin converting enzyme inhibitors in diabetes: experimental and human experience. Postgraduate medical journal, 1986, Volume: 62 Suppl 1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Bradykinin; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Kinins; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains	1986
Studies of the effects of insulin, bradykinin, and captopril on blood glucose levels of alloxan-diabetic rats. Advances in experimental medicine and biology, 1986, Volume: 198 Pt B Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Bradykinin; Captopril; Diabetes Mellitus, Experimental; Insulin; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Swine	1986
Effects of captopril and nicardipine on renal hyperfiltration and hypertrophy in uninephrectomized diabetic rats. Nihon Jinzo Gakkai shi, 1988, Volume: 30, Issue:3 Topics: Animals; Captopril; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hypertrophy; Kidney; Male; Nephrectomy; Nicardipine; Rats; Rats, Inbred Strains	1988
Blood pressure recovery following haemorrhage in rats with streptozotocin-induced diabetes mellitus. Circulatory shock, 1988, Volume: 26, Issue:3 Topics: Animals; Arginine Vasopressin; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Heart Rate; Hemorrhage; Hypotension; Male; Rats; Rats, Inbred Strains	1988
Diabetes mellitus and hypertension. State of the art lecture. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:2 Pt 2 Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Humans; Hypertension; Hypertension, Renovascular; Kidney; Norepinephrine; Prazosin; Rats; Time Factors; Vasopressins	1988
Pressor sensitivities to vasopressin, angiotensin II, or methoxamine in diabetic rats. The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 2 Topics: Angiotensin II; Animals; Arginine Vasopressin; Captopril; Diabetes Mellitus, Experimental; Heart Rate; Male; Methoxamine; Pentolinium Tartrate; Pressoreceptors; Rats; Rats, Inbred Strains; Renin; Vasopressins	1987
Abnormal blood pressure recovery during ganglion blockade in diabetic rats. The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 2 Topics: Animals; Blood Pressure; Captopril; Deamino Arginine Vasopressin; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Heart Rate; Insulin; Male; Pentolinium Tartrate; Rats; Rats, Inbred Strains	1987