Page last updated: 2024-08-23

captopril and Aging

captopril has been researched along with Aging in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (20.31)	18.7374
1990's	26 (40.63)	18.2507
2000's	16 (25.00)	29.6817
2010's	7 (10.94)	24.3611
2020's	2 (3.13)	2.80

Authors

Authors	Studies
Allani, SK; Bogue, MA; Cheng, CJ; Diaz, V; Dorigatti, AO; Dorigatti, J; Fernandez, E; Galecki, A; Gelfond, J; Ginsburg, B; Hamilton, KL; Harrison, DE; Javors, MA; Kaeberlein, M; Kornfeld, K; Kumar, S; Lombard, DB; Lopez-Cruzan, M; Maccchiarini, F; Miller, BF; Miller, RA; Nelson, JF; Newman, J; Rabinovitch, P; Reifsnyder, P; Rosenthal, NA; Salmon, AB; Strong, R; Suh, Y; Verdin, E; Weissbach, H	1
Bolduc, DL; Bouten, RM; Day, RM; George, J; Mattapallil, JJ; McCart, EA; Mog, SR; Mungunsukh, O; Panganiban, RAM; Rittase, WB; Snow, AL	1
Bourque, SL; Davidge, ST; Gragasin, FS	1
Hiraga, S; Komano, H; Liu, J; Liu, S; Maeda, T; Michikawa, M; Takahashi, S; Tanabe, C; Terayama, Y; Watanabe, A; Zou, K	1
Hongyo, K; Ito, N; Kamide, K; Kawai, T; Nakama, C; Onishi, M; Rakugi, H; Sugimoto, K; Takeya, Y; Yamamoto, K	1
Dietrich, N; Kornfeld, K; Kumar, S	1
Beltz, TG; Johnson, AK; Thunhorst, RL	1
Castro-Moreno, P; Del Valle-Mondragón, L; Hernández-Muñoz, R; Ibarra-Barajas, M; López-Guerrero, JJ; Pardo, JP; Pastelín-Hernández, G; Villalobos-Molina, R	1
Khimsuksri, S; Lerdweeraphon, W; Roysommuti, S; Thaeomor, A; Wyss, JM	1
Atkinson, J; Capdeville-Atkinson, C; Grima, M; Kieffer, P; Lartaud-Idjouadiene, I; Marque, V	1
Dias da Silva, VJ; Fazan, R; Ferreira Neto, E; Salgado, HC	1
Johnson, AK; Thunhorst, RL	1
Kadish, I; van Groen, T; Wyss, JM	1
Monument, MJ; Smith, FG	1
Atkinson, J; Chillon, JM; Dupuis, F; Limiñana, P	1
Ahmed, SB; Fisher, ND; Hollenberg, NK; Stevanovic, R	1
Dias da Silva, VJ; Fazan Júnior, R; Montano, N; Salgado, HC	1
Fisher, ND; Hollenberg, NK; Laffel, LM; Lansang, MC; Price, DA; Stevanovic, RD	1
Inoue, T; Kitamura, K; Kiyama, S; Kohda, Y; Nakayama, Y; Naruse, M; Nonoguchi, H; Tajiri, M; Tazoe, N; Tomita, K; Tomita, M	1
Aurell, M; Jodal, U; Sigström, L	1
Silberbauer, K; Stanek, B	1
Bühler, FR	1
McCarron, DA; Pulliam, JP	1
Doussau, MP; Giudicelli, JF; Richer, C	1
Ayres, NA; Gomez, RA; Lawton, WJ; Robillard, JE; VanOrden, DE; Weismann, DN	1
Clauser, E; Felix, D; Schelling, P	1
Cheung, DW	1
Canby, CA; Kawai, M; Rongish, BJ; Schraeger, JA; Tomanek, RJ	1
Morita, T; Nishimura, N; Takase, H	1
Araki, T; Ino, H; Mabuchi, H; Shimizu, M; Takeda, R; Yoshio, H	1
Karmarkar, MG; Lall, SB; Peshin, SS	1
Hollenberg, NK; Moore, TJ	1
Berecek, KH; Kadisha, I; King, K; Regan, CP; Roysommuti, S; Wyss, JM	1
Berecek, KH; Edwards, D; Wu, JN	1
Herzer, WA; Jackson, EK	1
Brudieux, R; Rakotondrazafy, J	1
Furukawa, S; Hayashi, K; Hirata, H; Masuda, Y; Shikada, K; Shudo, C; Sugita, H; Tamura, T; Tanaka, S; Tomita, K	1
Matsuda, K; Sekiguchi, F; Shimamura, K; Sunano, S	1
Del Bianco, A; Fregly, MJ; Rowland, NE	1
Carvalho, CR; Gontijo, JA; Saad, MJ; Thirone, AC; Velloso, LA	1
Baker, KM; Bing, OH; Boluyt, MO; Brooks, WW; Conrad, CH; Crow, MT; Dostal, DE; Lakatta, EG; O'Neill, L	1
Kandaswamy, V; Sen, S; Yang, CM; Young, D	1
Bosch, RJ; Del Moral, RG; Iglesias, MC; Masseroli, M; O'Valle, F; Pérez-Caballero, C; Ramírez, C; Rodríguez-Puyol, D; Rodríguez-Puyol, M; Ruiz-Torres, MP	1
Atkinson, J; Capdeville-Atkinson, C; Chillon, JM; Giummelly, P; Lartaud-Idjouadiene, I; Marque, V; Niederhoffer, N	1
Dolnikoff, MS; Furukawa, LN; Heimann, JC; Machado, UF; Okamoto, MM; Prada, P	1
Ishii, T; Matsuse, T; Ohga, E; Ouchi, Y; Suzuki, M; Teramoto, S	1
Dalton, GR; Jones, JV; Levi, AJ; Levy, A	1
Jednákovits, A; Kurucz, I; Nánási, PP	1
Chang, KC; Chen, HI; Peng, YI; Tsai, YF; Tseng, YZ	1
Chaupin, DF; Christie, RM; Daniel, SL; Entman, ML; Gould, KE; Hartley, CJ; Konkol, DL; Michael, LH; Pocius, JS; Sandusky, GE; Taffet, GE; Zachariah, JP	1
Dowell, RF; Prewitt, RL	1
Butenko, GM; Ena, LM; Magdich, LV; Tokar', AV	1
Chalmers, D; Lawson, DH; Whitehead, A	1
Arai, Y; Ghoda, K; Kajita, T; Liu, XF; Matsumiya, T; Ohgiya, N; Oka, T; Taniguchi, T	1
Leenen, FH; Wilczynski, EA; Yuan, B	1
Zawada, ET	1
Giuliani, L; Pacifici, GM; Santerini, S	1
Kimura, K; Matsuoka, H; Sugimoto, T; Tojo, A	1
Alden, SM; Boyd, CD; Deak, SB; Mackenzie, JW; Pierce, RA; Tozzi, CA	1
Saito, I; Saruta, T	1
Jelínek, J; Kunes, J; Lébl, M; Pohlová, I; Zicha, J	1
Boudailliez, B; el Esper, N; Fievet, P; Fournier, A; Idrissi, A; Makdassi, R; Remond, A; Renaud, H; Westeel, PF	1
Freis, ED	1
Creasey, WA; Funke, PT; McKinstry, DN; Sugerman, AA	1

Trials

1 trial(s) available for captopril and Aging

Article	Year
Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2005, Volume: 6, Issue:2 Topics: Adult; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Diabetes Mellitus, Type 1; Female; Hemodynamics; Humans; Kidney Function Tests; Male; Middle Aged; p-Aminohippuric Acid; Renal Circulation; Renin; Renin-Angiotensin System; Tetrazoles; Water-Electrolyte Balance	2005

Article

Year

Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus.

Journal of the renin-angiotensin-aldosterone system : JRAAS, 2005, Volume: 6, Issue:2

Topics: Adult; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Diabetes Mellitus, Type 1; Female; Hemodynamics; Humans; Kidney Function Tests; Male; Middle Aged; p-Aminohippuric Acid; Renal Circulation; Renin; Renin-Angiotensin System; Tetrazoles; Water-Electrolyte Balance

2005

Other Studies

63 other study(ies) available for captopril and Aging

Article	Year
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice. Aging cell, 2022, Volume: 21, Issue:12 Topics: Acarbose; Aging; Animals; Captopril; Female; Longevity; Male; Mice; Sirolimus	2022
Captopril reduces lung inflammation and accelerated senescence in response to thoracic radiation in mice. Journal of radiation research, 2021, Mar-10, Volume: 62, Issue:2 Topics: Aging; Animals; Apoptosis; Biomarkers; Captopril; Cytokines; Female; Inflammation Mediators; Lung; Macrophages, Alveolar; Mice, Inbred CBA; Pneumonia; Pulmonary Fibrosis; Spleen; Survival Analysis; Thorax; Whole-Body Irradiation; X-Rays	2021
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril. Anesthesia and analgesia, 2013, Volume: 116, Issue:4 Topics: Aging; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Area Under Curve; Blood Pressure; Captopril; Endothelium, Vascular; Enzyme Inhibitors; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Propofol; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents	2013
Aβ43 is the earliest-depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE. The American journal of pathology, 2013, Volume: 182, Issue:6 Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Brain; Captopril; Case-Control Studies; Disease Progression; Humans; Mice; Mice, Transgenic; Mutation; Peptide Fragments; Peptidyl-Dipeptidase A; Presenilins	2013
The influence of aging on the diagnosis of primary aldosteronism. Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; False Positive Reactions; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; Japan; Male; Middle Aged; Renin; Retrospective Studies	2014
Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span. PLoS genetics, 2016, Volume: 12, Issue:2 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Captopril; Electron Transport Complex III; Forkhead Transcription Factors; Longevity; Mutation; Phosphatidylinositol 3-Kinases; Receptor, Insulin; RNA Interference; Sirtuins; Stress, Physiological	2016
Drinking and arterial blood pressure responses to ANG II in young and old rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:5 Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Behavior, Animal; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Heart Rate; Infusions, Intravenous; Male; Minoxidil; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Urodynamics; Vasodilator Agents; Water-Electrolyte Balance	2010
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR. Autonomic & autacoid pharmacology, 2012, Volume: 32, Issue:3 Pt 4 Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Peptide Fragments; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Specific Pathogen-Free Organisms; Vascular Resistance	2012
Perinatal taurine imbalance alters the interplay of renin-angiotensin system and estrogen on glucose-insulin regulation in adult female rats. Advances in experimental medicine and biology, 2013, Volume: 776 Topics: Aging; Animals; Blood Glucose; Captopril; Estrogens; Fasting; Female; Glucose; Injections, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Maternal Exposure; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tamoxifen; Taurine	2013
Withdrawal reveals lack of effect of prolonged antihypertensive treatment on intrinsic aortic wall stiffness in senescent spontaneously hypertensive rats. Clinical and experimental pharmacology & physiology, 2002, Volume: 29, Issue:10 Topics: Aging; Animals; Antihypertensive Agents; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Captopril; Drug Administration Schedule; Elasticity; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance Withdrawal Syndrome	2002
Chronic converting enzyme inhibition normalizes QT interval in aging rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2002, Volume: 35, Issue:9 Topics: Aging; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Electrocardiography; Heart Rate; Male; Rats; Rats, Wistar	2002
Thirst and salt appetite responses in young and old Brown Norway rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:2 Topics: Aging; Animals; Antihypertensive Agents; Appetite; Body Fluids; Body Weight; Captopril; Drinking Behavior; Furosemide; Homeostasis; Male; Rats; Rats, Inbred BN; Sodium Chloride; Thirst; Water	2003
Age-related decline in spatial learning and memory: attenuation by captopril. Clinical and experimental hypertension (New York, N.Y. : 1993), 2003, Volume: 25, Issue:7 Topics: Aging; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Male; Maze Learning; Memory; Memory Disorders; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Space Perception	2003
Age-dependent effects of captopril on the arterial baroreflex control of heart rate in conscious lambs. Experimental physiology, 2003, Volume: 88, Issue:6 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Arteries; Baroreflex; Captopril; Heart Rate; Hemostasis; Sheep	2003
Captopril improves cerebrovascular structure and function in old hypertensive rats. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Blood Pressure; Brain; Captopril; Cerebral Hemorrhage; Cerebrovascular Circulation; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY	2005
Body mass index and angiotensin-dependent control of the renal circulation in healthy humans. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:6 Topics: Adult; Aging; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Body Mass Index; Captopril; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Reference Values; Renal Circulation; Renin; Sodium Chloride, Dietary; Vasodilation	2005
Effects of long-term angiotensin converting enzyme inhibition on cardiovascular variability in aging rats. Autonomic neuroscience : basic & clinical, 2006, Jan-30, Volume: 124, Issue:1-2 Topics: Aging; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Blood Pressure; Bradycardia; Captopril; Electrocardiography; Heart Rate; Hemodynamics; Male; Rats; Rats, Wistar; Tachycardia	2006
Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure. Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:1 Topics: Aging; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Body Weight; Captopril; Creatine; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged	2008
Angiotensin converting enzyme inhibitor treatment of hypertension in infancy and childhood. Scandinavian journal of urology and nephrology. Supplementum, 1984, Volume: 79 Topics: Adolescent; Aging; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Female; Humans; Hypertension; Infant; Male; Proline; Renin	1984
[Age dependence of the response of blood pressure, heart rate and plasma renin activity to captopril in essential hypertension]. Acta medica Austriaca, 1984, Volume: 11, Issue:3-4 Topics: Adult; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Proline; Renin	1984
Renin, renin inhibition and antihypertensive therapy. Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:7-8 Topics: Adrenergic beta-Antagonists; Aging; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Humans; Hypertension; Renin	1983
Hypertension: special concerns in geriatric patients. Geriatrics, 1984, Volume: 39, Issue:8 Topics: Adrenergic beta-Antagonists; Aged; Aging; Calcium Channel Blockers; Captopril; Diet, Sodium-Restricted; Diuretics; Humans; Hydralazine; Hypertension; Patient Compliance; Prazosin; Sympatholytics	1984
MK 421 and prevention of genetic hypertension development in young spontaneously hypertensive rats. European journal of pharmacology, 1982, Apr-08, Volume: 79, Issue:1-2 Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Dipeptides; Enalapril; Hemodynamics; Hypertension; Male; Norepinephrine; Rats	1982
Renal and adrenal responses to converting-enzyme inhibition in fetal and newborn life. The American journal of physiology, 1983, Volume: 244, Issue:2 Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Captopril; Fetal Blood; Kidney; Proline; Sheep	1983
Regulation of angiotensinogen in the central nervous system. Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:7-8 Topics: Aging; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Captopril; Cerebrovascular Disorders; Hypertension; Male; Rats; Rats, Inbred Strains	1983
Membrane potential of vascular smooth muscle and hypertension in spontaneously hypertensive rats. Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:8 Topics: Aging; Animals; Blood Pressure; Captopril; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium	1984
Normal left ventricular diastolic compliance after regression of hypertrophy. Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:3 Topics: Aging; Animals; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Collagen; Diastole; Elasticity; Hydrochlorothiazide; Hydroxyproline; In Vitro Techniques; Male; Rats; Rats, Inbred F344; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Ventricular Function, Left	1994
[Effects of chronic losartan treatment on myocardial, vascular structure and reactivity with aging in spontaneously hypertensive rats (SHR): its effects compared with those of captopril]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:6 Topics: Aging; Animals; Antihypertensive Agents; Arteriosclerosis; Biphenyl Compounds; Captopril; Coronary Circulation; Coronary Vessels; Heart Ventricles; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Organ Size; Rats; Rats, Inbred SHR; Tetrazoles; Vasoconstriction	1995
Effects of angiotensin-converting enzyme inhibitor and aldosterone antagonist on myocardial collagen in cardiomyopathic hamsters. Japanese circulation journal, 1995, Volume: 59, Issue:4 Topics: Aging; Animals; Body Weight; Canrenoic Acid; Captopril; Cardiomyopathies; Collagen; Cricetinae; Disease Models, Animal; Heart; Hydroxyproline; Male; Organ Size	1995
Plasma renin activity in normal healthy volunteers: effect of physiological variables. Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:1 Topics: Adolescent; Adult; Aged; Aging; Angiotensin I; Blood Pressure; Captopril; Child; Child, Preschool; Diet, Sodium-Restricted; Female; Humans; Male; Middle Aged; Posture; Radioimmunoassay; Renin; Sex Factors; Sodium, Dietary; Supine Position	1995
Age and the renal blood supply: renal vascular responses to angiotensin converting enzyme inhibition in healthy humans. Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:8 Topics: Adolescent; Adult; Aged; Aging; Captopril; Female; Humans; Male; Middle Aged; Reference Values; Renal Circulation; Renin	1994
Salt-induced hypertension in normotensive spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 1 Topics: Aging; Animals; Blood Pressure; Captopril; Diet, Sodium-Restricted; Drug Administration Schedule; Female; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride; Time Factors	1994
Changes in renal angiotensin II receptors in spontaneously hypertensive rats by early treatment with the angiotensin-converting enzyme inhibitor captopril. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Binding, Competitive; Captopril; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Reference Values	1994
Angiotensin II/prostaglandin I2 interactions in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:5 Topics: Aging; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Captopril; Cardiac Output; Dose-Response Relationship, Drug; Drug Interactions; Epoprostenol; Hemodynamics; Indomethacin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Splanchnic Circulation; Vascular Resistance	1993
Age-related change in plasma aldosterone response to exogenous angiotensin II in the rat. Hormone research, 1993, Volume: 39, Issue:3-4 Topics: Adrenal Cortex; Aging; Aldosterone; Angiotensin II; Animals; Captopril; Corticosterone; Dexamethasone; Female; Kinetics; Potassium; Rats	1993
Effects of efonidipine, nicardipine and captopril on proteinuria in aged spontaneously hypertensive rats. Arzneimittel-Forschung, 1996, Volume: 46, Issue:9 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Creatinine; Dihydropyridines; Heart Rate; Hypertension; Kidney; Male; Nicardipine; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred SHR	1996
Blood pressure and age-dependent changes of endothelium-dependent tension oscillations in different strains of spontaneously hypertensive rats. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1996, Volume: 32, Issue:4 Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Endothelium, Vascular; Hydralazine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar	1996
Age-related decline in thirst and sodium appetite in rats related to kininase II inhibition. Regulatory peptides, 1996, Oct-22, Volume: 66, Issue:3 Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Drinking; Female; Rats; Rats, Inbred F344; Sodium Chloride, Dietary	1996
Effect of captopril, losartan, and bradykinin on early steps of insulin action. Diabetes, 1997, Volume: 46, Issue:12 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Insulin; Insulin Receptor Substrate Proteins; Liver; Losartan; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin	1997
Captopril modifies gene expression in hypertrophied and failing hearts of aged spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:6 Topics: Aging; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Atrial Natriuretic Factor; Captopril; Cardiomegaly; Gene Expression Regulation; Heart; Heart Failure; Hypertension; Male; Myosin Heavy Chains; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta	1997
Changes in collagen phenotypes during progression and regression of cardiac hypertrophy. Cardiovascular research, 1997, Volume: 36, Issue:2 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Captopril; Cardiomegaly; Collagen; Heart Failure; Hydroxyproline; Lisinopril; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA	1997
Age-related increase in expression of TGF-beta1 in the rat kidney: relationship to morphologic changes. Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:5 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Immunohistochemistry; Kidney; Kidney Cortex; Kidney Glomerulus; Male; Polymerase Chain Reaction; Proteinuria; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta	1998
Effects of aging and antihypertensive treatment on aortic internal diameter in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2 Topics: Age Factors; Aging; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Diuretics; Hydrochlorothiazide; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride Symporter Inhibitors; Time Factors	1999
High- or low-salt diet from weaning to adulthood: effect on insulin sensitivity in Wistar rats. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biological Transport; Body Weight; Captopril; Diet, Sodium-Restricted; Glucose; Glucose Transporter Type 4; Hyperinsulinism; Insulin Resistance; Losartan; Male; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Wistar; Sodium Chloride, Dietary; Weaning	2000
Inhibitory effects of angiotensin-converting enzyme (ACE) inhibitors on oxygen radicals produced by bronchoalveolar lavage cells in young and aged guinea pigs. Aging (Milan, Italy), 2000, Volume: 12, Issue:1 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Bronchoalveolar Lavage Fluid; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Lisinopril; Macrophages, Alveolar; Male; Reactive Oxygen Species	2000
Changes in contractile protein gene expression with ageing and with captopril-induced regression of hypertrophy in the spontaneously hypertensive rats. Journal of hypertension, 2000, Volume: 18, Issue:9 Topics: Actins; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Gene Expression; Hypertrophy, Left Ventricular; In Situ Hybridization; Isomerism; Male; Muscle, Skeletal; Myocardium; Myosin Heavy Chains; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger	2000
Effect of subchronic bimoclomol treatment on vascular responsiveness and heat shock protein production in spontaneously hypertensive rats. Life sciences, 2000, Aug-25, Volume: 67, Issue:14 Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Endothelium, Vascular; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Hypertension; Imides; In Vitro Techniques; Male; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; RNA, Messenger	2000
Hypotensive effects of captopril on physical properties of the arterial system in young and adult rats. Biogerontology, 2001, Volume: 2, Issue:1 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Body Weight; Captopril; Hemodynamics; Male; Rats; Rats, Inbred WKY	2001
Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2 Topics: Age Factors; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Captopril; Cardiomegaly; Coronary Disease; Disease Models, Animal; Heart Failure; Heart Septum; Ligation; Male; Mice; Mice, Inbred C57BL; Multivariate Analysis; Myocardial Infarction; Survival Rate	2002
Structural vascular adaptations during the developmental stages of hypertension in the spontaneously hypertensive rat. Bibliotheca anatomica, 1979, Issue:18 Topics: Aging; Animals; Blood Pressure; Captopril; Cardiac Output; Hypertension; Male; Papaverine; Pentolinium Tartrate; Rats; Vascular Resistance; Vasodilation	1979
[Effect of antihypertensive therapy with captopril on gluco- and mineralocorticoid receptors of peripheral blood lymphocytes in hypertensive patients of various age]. Kardiologiia, 1992, Volume: 32, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Captopril; Female; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Radioligand Assay; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid	1992
Postmarketing surveillance of captopril for hypertension. British journal of clinical pharmacology, 1992, Volume: 34, Issue:3 Topics: Aged; Aging; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Risk Factors	1992
Effects of the subcutaneous administration of enkephalins on tail-flick response and righting reflex of developing rats. Brain research. Developmental brain research, 1992, Oct-23, Volume: 69, Issue:2 Topics: Aging; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Female; Glycopeptides; Injections, Subcutaneous; Male; Oligopeptides; Pain; Peptides; Posture; Protease Inhibitors; Rats; Rats, Wistar; Reflex	1992
Dietary sodium restriction and the development of two-kidney, one-clip hypertension in young versus adult rats. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:4 Topics: Aging; Animals; Blood Pressure; Body Weight; Captopril; Diet, Sodium-Restricted; Hypertension, Renovascular; Male; Organ Size; Rats; Rats, Inbred Strains; Renin	1992
Geriatrics nephrology. Journal of clinical pharmacology, 1992, Volume: 32, Issue:4 Topics: Aged; Aging; Captopril; Digoxin; Furosemide; Heart Failure; Humans; Hypertension; Kidney Diseases; Lung Diseases, Obstructive; Male	1992
Methylation of captopril in human liver, kidney and intestine. Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:9 Topics: Adult; Aged; Aging; Captopril; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Kidney; Kidney Cortex; Kidney Medulla; Liver; Male; Methylation; Methyltransferases; Microsomes; Microsomes, Liver; Middle Aged	1991
Renal arteriolar diameters in spontaneously hypertensive rats. Vascular cast study. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:1 Topics: Aging; Animals; Arterioles; Blood Pressure; Body Weight; Captopril; Hydralazine; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Trichlormethiazide	1991
Changes in aortic levels of tropoelastin mRNA following treatment of rats with the antihypertensive drugs captopril and hydralazine. The Journal of surgical research, 1991, Volume: 51, Issue:6 Topics: Aging; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Hydralazine; Nucleic Acid Hybridization; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Tropoelastin	1991
[Therapeutic drug monitoring of inhibitors of renin-angiotensin system]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48 Suppl Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Biological Availability; Captopril; Enalapril; Humans; Radioligand Assay; Saralasin	1990
Haemodynamics and the participation of pressor systems in young and adult rats with age-dependent DOCA-salt hypertension. Physiologia Bohemoslovaca, 1987, Volume: 36, Issue:1 Topics: Aging; Animals; Blood Pressure; Captopril; Desoxycorticosterone; Hemodynamics; Hypertension; Male; Prazosin; Rats; Rats, Inbred Strains; Sodium Chloride; Vasomotor System	1987
The captopril challenge test as a screening test for renovascular hypertension. Kidney international. Supplement, 1988, Volume: 25 Topics: Adolescent; Adult; Aged; Aging; Arterial Occlusive Diseases; Blood Pressure; Captopril; Child; Constriction, Pathologic; Female; Humans; Hypertension, Renovascular; Kidney; Male; Middle Aged; Renal Artery; Renin	1988
Age and antihypertensive drugs (hydrochlorothiazide, bendroflumethiazide, nadolol and captopril). The American journal of cardiology, 1988, Jan-01, Volume: 61, Issue:1 Topics: Adult; Aged; Aging; Bendroflumethiazide; Black People; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Random Allocation; White People	1988
Pharmacokinetics of captopril in elderly healthy male volunteers. Journal of clinical pharmacology, 1986, Volume: 26, Issue:4 Topics: Aged; Aging; Biotransformation; Captopril; Humans; Kinetics; Male; Protein Binding	1986