Compounds > captopril
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captopril and Acute Liver Injury, Drug-Induced

captopril has been researched along with Acute Liver Injury, Drug-Induced in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's7 (30.43)18.2507
2000's2 (8.70)29.6817
2010's9 (39.13)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Eid, BG; El-Shitany, NA1
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T1
Abdelrahman, AM; Ibrahim, SA; Kelleni, MT1
Cabello Clotet, N; Fernández Alons, E; Gargantilla Madera, P; Garzarán, A; Pardo Redondo, A; San Román Montero, JM; Vergas García, J1
Andrade, RJ; Barriocanal, A; Borraz, Y; Costa, J; Durán, JA; Fernández, MC; García-Cortés, M; García-Muņoz, B; Guarner, C; Hidalgo, R; Kaplowitz, N; Lucena, MI; Muņoz-Yagüe, T; Pachkoria, K; Pelaez, G; Planas, R; Rodrigo, L; Romero-Gomez, M; Salmerón, J1
Lazda, E; Parfrey, P; Vandenburg, M; Wright, P1
Batho, JM; Beuve-Mery, P; Peny, J; Ryckelynck, JP1
Burns, CM; Hagley, MT; Hulisz, DT1
Bondía, A; Corbacho, L; Deira, JL; García, P; Gascón, A; Lerma, JL; Martín, B; Tabernero, JM1
González Carro, PS; Legaz Huidobro, ML; Pérez Roldán, F; Ruiz Carrillo, F; Saez Bravo, JM1
Habior, A1
Clementsen, PS; Hansen, BA; Høyer, S; Pedersen, JH1
Benak, RL; Hagley, MT; Hulisz, DT1
Livshitz, T; Putterman, C1
Bellary, SV; Isaacs, PE; Scott, AW1
Aliot, E; Gilgenkrantz, JM; Marie, PY; Trechot, P; Zannad, F1

Reviews

2 review(s) available for captopril and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hepatotoxicity associated with angiotensin-converting enzyme inhibitors.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Chemical and Drug Induced Liver Injury; Enalapril; Female; Humans; Male; Middle Aged; Time Factors

1993

Other Studies

21 other study(ies) available for captopril and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Captopril downregulates expression of Bax/cytochrome C/caspase-3 apoptotic pathway, reduces inflammation, and oxidative stress in cisplatin-induced acute hepatic injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Captopril; Caspase 3; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cisplatin; Cytochromes c; Down-Regulation; Humans; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction

2021
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine

2014
Effect of captopril and telmisartan on methotrexate-induced hepatotoxicity in rats: impact of oxidative stress, inflammation and apoptosis.
    Toxicology mechanisms and methods, 2016, Volume: 26, Issue:5

    Topics: Animals; Apoptosis; Benzimidazoles; Benzoates; Captopril; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Immunohistochemistry; Liver Function Tests; Male; Methotrexate; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Rats; Telmisartan

2016
[Progressive icterus in a 56 years old man].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Chemical and Drug Induced Liver Injury; Humans; Jaundice; Male; Middle Aged

2002
Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Atorvastatin; Azepines; Captopril; Cardiovascular Agents; Central Nervous System Agents; Chemical and Drug Induced Liver Injury; Chronic Disease; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Heptanoic Acids; Humans; Liver; Liver Diseases; Male; Middle Aged; Pyrroles; Registries; Spain

2006
Hepatitis associated with captopril treatment.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:1

    Topics: Captopril; Chemical and Drug Induced Liver Injury; Humans; Hypertension; Proline

1981
[Hepatitis due to captopril].
    La Nouvelle presse medicale, 1982, May-29, Volume: 11, Issue:25

    Topics: Adult; Captopril; Chemical and Drug Induced Liver Injury; Female; Humans; Proline

1982
Captopril hepatotoxicity in a case of renal crisis due to systemic sclerosis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:8

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chemical and Drug Induced Liver Injury; Female; Humans; Kidney Diseases; Scleroderma, Systemic

1997
[Cholestatic hepatitis caused by captopril].
    Revista espanola de enfermedades digestivas, 1998, Volume: 90, Issue:5

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Humans; Male

1998
[Effect of captopril on glutathione level in the liver and paracetamol-induced liver damage in rats].
    Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 87, Issue:6

    Topics: Acetaminophen; Animals; Captopril; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Liver; Male; Rats; Rats, Sprague-Dawley; Time Factors

1992
[Captopril-induced toxic hepatitis].
    Ugeskrift for laeger, 1992, Oct-12, Volume: 154, Issue:42

    Topics: Aged; Captopril; Chemical and Drug Induced Liver Injury; Female; Hepatorenal Syndrome; Humans; Liver

1992
Suspected cross-reactivity of enalapril- and captopril-induced hepatotoxicity.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Captopril; Chemical and Drug Induced Liver Injury; Enalapril; Humans; Liver Diseases; Male; Middle Aged

1992
[Captopril-induced liver dysfunction].
    Harefuah, 1991, Volume: 121, Issue:3-4

    Topics: Aged; Captopril; Chemical and Drug Induced Liver Injury; Humans; Male

1991
Captopril and the liver.
    Lancet (London, England), 1989, Aug-26, Volume: 2, Issue:8661

    Topics: Acute Disease; Aged; Aged, 80 and over; Captopril; Chemical and Drug Induced Liver Injury; Female; Humans; Hypertension; Male

1989
Cytolytic hepatitis with captopril but not with enalapril.
    Cardiovascular drugs and therapy, 1988, Volume: 1, Issue:6

    Topics: Captopril; Chemical and Drug Induced Liver Injury; Enalapril; Humans; Male; Middle Aged

1988