capsaicin and Peripheral Nerve Diseases

capsaicin has been researched along with Peripheral Nerve Diseases in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.95)18.7374
1990's15 (19.74)18.2507
2000's28 (36.84)29.6817
2010's25 (32.89)24.3611
2020's5 (6.58)2.80

Authors

AuthorsStudies
Alsalem, M; Barakat, NA; El-Salem, K; Haddad, M; Jaffal, SM; Saleh, T1
Gestosa, SVS; Lares, AMG; Mulenas, NME; Ruivo, EFM1
Cabezón-Gutiérrez, L; Custodio-Cabello, S; Khosravi-Shahi, P; Palka-Kotlowska, M1
Barkai, O; Binshtok, AM; Butterman, R; Katz, B; Lev, S1
Baron, R; Diel, I; Maihöfner, C; Quandel, T; Tesch, H1
Cull-Candy, SG; Farrant, M; Sullivan, SJ1
Beitz, AJ; Kim, SJ; Kwon, SG; Lee, JH; Roh, DH; Yeo, JH; Yoon, SY1
Jäger-Becker, D1
Yosipovitch, G1
Brown, S; Simpson, DM; Tobias, JK; Vanhove, GF1
Heskamp, ML; Maihofner, C1
Anderson, MJ; Christiansen, BA; Genetos, DC; Heffner, MA; Yeh, GC1
Bogdanovich, A; Busquets, C; Faulí, A; Giménez-Milà, M; Hernández-Cera, C; Moreno, LA; Navarro, MA; Ojeda, A; Videla, S1
Brenaut, E; Castela, E; Erfan, N; Lacour, JP; Lantéri-Minet, M; Misery, L; Passeron, T1
Erlandson, M; Legerski, P; Onysko, M; Potthoff, J1
Burness, CB; McCormack, PL1
Fehrenbacher, JC; Gracias, NG; Pittman, SK1
Bentley, A; Mankowski, C; Patel, S; Poole, C; Trueman, D1
Şavk, E1
Adler, JE; Skoff, AM; Zhao, C1
Babbar, S; Beliveau, M; Bley, K; Chanda, S; Marier, JF; Mouksassi, MS; Vanhove, GF1
Keppel Hesselink, JM; Kopsky, DJ1
Coderre, TJ; Kumar, N; Laferriere, A; Poon, T; Yu, JS1
Brown, S; Gazda, S; Lu, SP; Simpson, DM; Tobias, JK; Vanhove, GF; Webster, LR1
Baron, R; Mahn, F1
McCormack, PL1
Cherry, CL; Cox, S; Marshall, SJ; Phillips, TJ; Rice, AS1
Chapman, H; Hao, B; Huang, JL; Koivisto, A; Kuokkanen, K; Pertovaara, A; Saarnilehto, M; Wang, YX; Wei, H1
Lu, B; Murphy, FT; Peppin, JF; Tobias, JK; Vanhove, GF; Webster, LR1
Benemei, S; Creminon, C; Fusi, C; Geppetti, P; Materazzi, S; Nassini, R; Nilius, B; Patacchini, R; Pedretti, P; Prenen, J1
Gibbons, CH; Illigens, BM1
Chapman, V; Kelly, S1
Liu, XJ; Sawynok, J; White, TD1
Fox, AJ; McIntyre, P; Medhurst, SJ; Panesar, M; Patel, S; Urban, L; Walker, KM1
Li, GD; Zhao, ZQ; Zhou, Y1
Atweh, SF; Bach, JF; Dardenne, M; Jabbur, SJ; Saadé, NE; Safieth-Garabedian, B1
Magerl, W; Treede, RD1
Kempler, P1
Freeman, R1
Lonovics, J; Németh, J; Peitl, B; Porszasz, R; Sári, R; Sziklai, I; Szilvássy, J; Szilvássy, Z1
Bynum, T; Eisenach, JC; Hayashida, KI; Vincler, M1
Brower, JB; Casano, AR; Herman, JH; Herman, RM; Stoddard, DG; Targovnik, JH; Tearse, P1
Bromberg, MB; Herrmann, DN1
Hahn, K; Hauer, P; McArthur, JC; Polydefkis, M; Triolo, A1
Furue, H; Hasegawa, S; Inoue, K; Ishii, S; Koizumi, S; Masuda, T; Nagata, K; Nakamura, K; Shimizu, T; Tozaki-Saitoh, H; Tsuda, M; Yamashita, T; Yoshimura, M1
Abbott, L; Aschenbrenner, J; Collins, M; Hart, C; Visovsky, C1
Cheepudomwit, T; Griffin, JW; Güzelsu, E; Höke, A; Zhou, C1
Chiang, H; Hsieh, ST; Hsieh, YL; Tseng, TJ1
Hwang, SJ; Kim, E; Kim, J; Kim, SM; Lee, SE; Shin, HK1
Anand, P; Anand, U; Birch, R; Bountra, C; Chessell, I; Otto, WR; Sinisi, M1
Thomas, PK1
Campbell, JN; Cervero, F; Meyer, RA1
Epstein, JB; Marcoe, JH1
Cole, JD; Treede, RD1
Dyck, PJ; Litchy, WJ; Low, PA; O'Brien, PC; Opfer-Gehrking, TL1
Emanuele, MA; Emanuele, NV1
De Mey, JG; Jacobs, MJ; Kitslaar, PJ; Kurvers, HA; Reneman, RS; Rouwet, EV; Slaaf, DW; Tangelder, GJ; van den Wildenberg, FA1
Flores, CM; Harding-Rose, C; Hargreaves, KM; Kilo, S1
Huang, HT; Lo, YK1
Formaglio, F; Lauritano, D; Salvato, A; Spadari, F; Zambellini Artini, M1
Aloe, L; Lundeberg, T; Manni, L; Tirassa, P1
Ferrans, CE; Lashley, FR; Paice, JA; Pitrak, D; Shott, S; Vizgirda, V1
McCleane, G1
Kennedy, WR; Khalili, N; Simone, DA; Wendelschafer-Crabb, G1
Yonehara, N; Yoshimura, M1
Hama, AT1
Baumgärtner, U; Hopf, HC; Klein, T; Magerl, W; Treede, RD1
Ollat, H1
Harkness, DH; Larson, AA; Skilling, SR1
Abelli, L; Astolfi, M; Conte, B; Dahl, D; Ferri, GL; Geppetti, P; Maggi, CA; Parlani, M; Polak, JM1
Rumsfield, JA; West, DP1
Dubner, R1
Cotton, P1
Hartung, HP; Heininger, K; Toyka, KV1
Helme, RD1

Reviews

17 review(s) available for capsaicin and Peripheral Nerve Diseases

ArticleYear
High-Dose 8% Capsaicin Patch in Treatment of Chemotherapy-Induced Peripheral Neuropathy. A Systematic Review.
    Journal of pain and symptom management, 2020, Volume: 60, Issue:5

    Topics: Antineoplastic Agents; Capsaicin; Humans; Peripheral Nervous System Diseases; Prospective Studies; Retrospective Studies; Transdermal Patch

2020
Chemotherapy-induced peripheral neuropathy (CIPN): current therapies and topical treatment option with high-concentration capsaicin.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:8

    Topics: Capsaicin; Humans; Neoplasms; Peripheral Nervous System Diseases; Quality of Life

2021
[Capsaicin (QUTENZA), dermatological use].
    Journal de pharmacie de Belgique, 2014, Issue:4

    Topics: Administration, Topical; Capsaicin; Humans; Peripheral Nervous System Diseases

2014
Targeting neuropathic pain: consider these alternatives.
    The Journal of family practice, 2015, Volume: 64, Issue:8

    Topics: Acetylcarnitine; Capsaicin; Complementary Therapies; Family Practice; gamma-Linolenic Acid; Humans; Magnesium; Neuralgia; Peripheral Nervous System Diseases; Thioctic Acid; Vitamin B Complex

2015
Capsaicin 8 % Patch: A Review in Peripheral Neuropathic Pain.
    Drugs, 2016, Volume: 76, Issue:1

    Topics: Capsaicin; Diabetic Neuropathies; Humans; Neuralgia, Postherpetic; Pain Management; Peripheral Nervous System Diseases; Pregabalin; Sensory System Agents; Transdermal Patch

2016
Neurologic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Acupuncture Therapy; Amines; Anesthetics, Local; Anticonvulsants; Antipruritics; Botulinum Toxins, Type A; Calcineurin Inhibitors; Cannabinoid Receptor Agonists; Capsaicin; Cyclohexanecarboxylic Acids; Doxepin; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Peripheral Nervous System Diseases; Phototherapy; Physical Therapy Modalities; Pregabalin; Pruritus; Tacrolimus; Transcranial Magnetic Stimulation; Transcutaneous Electric Nerve Stimulation

2016
Capsaicin dermal patch: in non-diabetic peripheral neuropathic pain.
    Drugs, 2010, Oct-01, Volume: 70, Issue:14

    Topics: Administration, Cutaneous; Capsaicin; Dose-Response Relationship, Drug; Humans; Peripheral Nervous System Diseases; Sensory System Agents

2010
Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials.
    PloS one, 2010, Dec-28, Volume: 5, Issue:12

    Topics: Analgesics; Anti-Retroviral Agents; Cannabis; Capsaicin; HIV Infections; Humans; Nerve Growth Factor; Peripheral Nervous System Diseases; Placebos; Plant Extracts; Randomized Controlled Trials as Topic; Research Design; Risk; Treatment Outcome

2010
[Treatment of neuropathies].
    Orvosi hetilap, 2004, May-23, Volume: 145, Issue:21

    Topics: Adjuvants, Immunologic; Capsaicin; Diabetic Neuropathies; Diagnosis, Differential; Humans; Liver Diseases; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Thiamine; Treatment Outcome

2004
The treatment of neuropathic pain.
    CNS spectrums, 2005, Volume: 10, Issue:9

    Topics: Anti-Arrhythmia Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Capsaicin; Diabetes Mellitus, Type 2; Humans; Neuralgia, Postherpetic; Nociceptors; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Sodium Channels

2005
Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy.
    Clinical journal of oncology nursing, 2007, Volume: 11, Issue:6

    Topics: Acetylcarnitine; Acupuncture Therapy; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Antioxidants; Calcium; Capsaicin; Evidence-Based Medicine; Exercise Therapy; Glutamine; Glutathione; Humans; Infrared Rays; Magnesium; Neoplasms; Nurse's Role; Nursing Research; Oncology Nursing; Patient Education as Topic; Peripheral Nervous System Diseases; Research Design; Sensory System Agents; Transcutaneous Electric Nerve Stimulation; Vitamin E

2007
The peripheral nervous system as a target for toxic substances.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: 6-Aminonicotinamide; Age Factors; Animals; Axons; Capsaicin; Demyelinating Diseases; Diphtheria Toxin; Doxorubicin; Humans; Methylmercury Compounds; Mice; Myelin Sheath; Neurons; Peripheral Nervous System Diseases; Rats; Schwann Cells; Vincristine

1984
Drugs to treat the tissue complications of diabetes: peripheral neuropathy.
    Comprehensive therapy, 1995, Volume: 21, Issue:10

    Topics: Administration, Topical; Analgesics; Antidepressive Agents, Tricyclic; Capsaicin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Forecasting; Humans; Pain Threshold; Peripheral Nervous System Diseases

1995
[Etiopathogenic, clinical-diagnostic and therapeutic aspects of the burning mouth syndrome. Research and treatment protocols in a patient group].
    Minerva stomatologica, 1998, Volume: 47, Issue:6

    Topics: Adult; Aged; Analgesics; Benzodiazepines; Burning Mouth Syndrome; Capsaicin; Female; Humans; Male; Middle Aged; Mouth Mucosa; Peripheral Nervous System Diseases; Polyneuropathies; Tongue

1998
[Pharmacological treatment of neuropathic pain].
    Revue neurologique, 1992, Volume: 148, Issue:8-9

    Topics: Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Baclofen; Capsaicin; Chronic Disease; Diabetic Neuropathies; Humans; Narcotics; Neuralgia; Pain; Peripheral Nervous System Diseases

1992
Topical capsaicin in dermatologic and peripheral pain disorders.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:4

    Topics: Administration, Topical; Capsaicin; Humans; Pain; Peripheral Nervous System Diseases; Skin Diseases

1991
[Neuromuscular manifestations of HIV-1 and HTLV-I infections].
    Deutsche medizinische Wochenschrift (1946), 1988, Dec-16, Volume: 113, Issue:50

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adrenal Cortex Hormones; Capsaicin; Carbamazepine; Demyelinating Diseases; Ganciclovir; HIV-1; HTLV-I Infections; Humans; Muscular Diseases; Neuritis; Neuromuscular Diseases; Peripheral Nervous System Diseases; Polyneuropathies; Zidovudine

1988

Trials

12 trial(s) available for capsaicin and Peripheral Nerve Diseases

ArticleYear
[In process].
    Medizinische Monatsschrift fur Pharmazeuten, 2016, Volume: 39, Issue:8

    Topics: Administration, Cutaneous; Capsaicin; Diabetic Neuropathies; Double-Blind Method; Humans; Neuralgia; Peripheral Nervous System Diseases

2016
NGX-4010, a capsaicin 8% dermal patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: results of a 52-week open-label study.
    The Clinical journal of pain, 2014, Volume: 30, Issue:2

    Topics: Adult; Capsaicin; Double-Blind Method; Endpoint Determination; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neuralgia; Neurologic Examination; Pain Management; Pain Measurement; Patient Satisfaction; Peripheral Nervous System Diseases; Sensory Receptor Cells; Skin; Transdermal Patch; Treatment Outcome

2014
Prospective, non-interventional study on the tolerability and analgesic effectiveness over 12 weeks after a single application of capsaicin 8% cutaneous patch in 1044 patients with peripheral neuropathic pain: first results of the QUEPP study.
    Current medical research and opinion, 2013, Volume: 29, Issue:6

    Topics: Administration, Cutaneous; Analgesics; Capsaicin; Female; Humans; Male; Middle Aged; Neuralgia; Pain Management; Peripheral Nervous System Diseases; Transdermal Patch; Treatment Outcome

2013
Pharmacokinetic analysis of capsaicin after topical administration of a high-concentration capsaicin patch to patients with peripheral neuropathic pain.
    Therapeutic drug monitoring, 2009, Volume: 31, Issue:4

    Topics: Administration, Cutaneous; Administration, Topical; Capsaicin; Capsicum; Dosage Forms; Dose-Response Relationship, Drug; Female; Half-Life; HIV Infections; HIV-1; Humans; Kinetics; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Treatment Outcome

2009
Efficacy, safety, and tolerability of NGX-4010, capsaicin 8% patch, in an open-label study of patients with peripheral neuropathic pain.
    Diabetes research and clinical practice, 2011, Volume: 93, Issue:2

    Topics: Aged; Anesthetics, Local; Capsaicin; Diabetic Neuropathies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain; Peripheral Nervous System Diseases; Polyneuropathies; Sensory System Agents; Transdermal Patch; Treatment Outcome

2011
A psychophysical study of secondary hyperalgesia: evidence for increased pain to input from nociceptors.
    Pain, 1994, Volume: 58, Issue:1

    Topics: Adult; Animals; Capsaicin; Cold Temperature; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; Male; Mechanoreceptors; Nociceptors; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Wool

1994
Topical application of capsaicin for treatment of oral neuropathic pain and trigeminal neuralgia.
    Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Burning Mouth Syndrome; Capsaicin; Facial Pain; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Toothache; Treatment Outcome; Trigeminal Neuralgia

1994
Double-blind, placebo-controlled study of the application of capsaicin cream in chronic distal painful polyneuropathy.
    Pain, 1995, Volume: 62, Issue:2

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Capsaicin; Double-Blind Method; Female; Humans; Male; Middle Aged; Nerve Fibers; Neuralgia; Ointments; Peripheral Nervous System Diseases; Placebos; Sweat

1995
Topical capsaicin in the management of HIV-associated peripheral neuropathy.
    Journal of pain and symptom management, 2000, Volume: 19, Issue:1

    Topics: Administration, Topical; Adult; Capsaicin; Double-Blind Method; Female; HIV Infections; Humans; Male; Middle Aged; Palliative Care; Peripheral Nervous System Diseases; Treatment Failure

2000
Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study.
    British journal of clinical pharmacology, 2000, Volume: 49, Issue:6

    Topics: Administration, Topical; Adult; Antidepressive Agents, Tricyclic; Capsaicin; Chronic Disease; Double-Blind Method; Doxepin; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Paresthesia; Peripheral Nervous System Diseases

2000
Influence of thermode size for detecting heat pain dysfunction in a capsaicin model of epidermal nerve fiber loss.
    Pain, 2001, Volume: 91, Issue:3

    Topics: Adult; Aged; Biopsy; Capsaicin; Epidermis; Female; Hot Temperature; Humans; Male; Middle Aged; Nerve Degeneration; Nerve Fibers; Nerve Regeneration; Pain Threshold; Peripheral Nervous System Diseases; Sensitivity and Specificity; Thiolester Hydrolases; Ubiquitin Thiolesterase

2001
Compliance problems, placebo effect cloud trials of topical analgesic.
    JAMA, 1990, Jul-04, Volume: 264, Issue:1

    Topics: Capsaicin; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; HIV Infections; Humans; Ointments; Patient Compliance; Peripheral Nervous System Diseases; Placebo Effect

1990

Other Studies

47 other study(ies) available for capsaicin and Peripheral Nerve Diseases

ArticleYear
Interaction of the synthetic cannabinoid WIN55212 with tramadol on nociceptive thresholds and core body temperature in a chemotherapy-induced peripheral neuropathy pain model.
    Neuroreport, 2023, 05-17, Volume: 34, Issue:8

    Topics: Analgesics; Animals; Antineoplastic Agents; Body Temperature; Calcium; Cannabinoids; Capsaicin; Ganglia, Spinal; Male; Nociception; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Tramadol

2023
Peripheral Neuropathy Associated with Hypereosinophilic Syndrome: A Clinical Therapeutic Success with Capsaicin 8% Patch.
    Journal of pain & palliative care pharmacotherapy, 2020, Volume: 34, Issue:3

    Topics: Capsaicin; Humans; Hypereosinophilic Syndrome; Male; Middle Aged; Neuralgia; Pain Management; Peripheral Nervous System Diseases; Quality of Life; Transdermal Patch

2020
The Input-Output Relation of Primary Nociceptive Neurons is Determined by the Morphology of the Peripheral Nociceptive Terminals.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020, 12-02, Volume: 40, Issue:49

    Topics: Action Potentials; Capsaicin; Computer Simulation; Humans; Models, Neurological; Neuralgia; Nociception; Nociceptors; Peripheral Nerves; Peripheral Nervous System Diseases; Presynaptic Terminals; Sensory Receptor Cells; Sodium Channels; Synaptic Transmission

2020
TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 06-21, Volume: 37, Issue:25

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Capsaicin; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Fibers, Unmyelinated; Neuronal Plasticity; Peripheral Nervous System Diseases; Posterior Horn Cells; Receptors, AMPA; Synaptic Transmission

2017
Differential Development of Facial and Hind Paw Allodynia in a Nitroglycerin-Induced Mouse Model of Chronic Migraine: Role of Capsaicin Sensitive Primary Afferents.
    Biological & pharmaceutical bulletin, 2018, Feb-01, Volume: 41, Issue:2

    Topics: Animals; Capsaicin; Cold Temperature; Diterpenes; Drug Resistance; Facial Nerve Diseases; Hindlimb; Hot Temperature; Hyperalgesia; Male; Mice, Inbred C57BL; Mice, Knockout; Migraine Disorders; Nerve Tissue Proteins; Neurons, Afferent; Neurotoxins; Nitric Oxide Donors; Nitroglycerin; Organ Specificity; Peripheral Nervous System Diseases; Sensory System Agents; TRPV Cation Channels

2018
The 8% capsaicin - a hot medicine for neuropathic itch.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:9

    Topics: Antipruritics; Capsaicin; Humans; Nerve Fibers; Peripheral Nervous System Diseases; Pruritus; TRPV Cation Channels

2018
Altered bone development in a mouse model of peripheral sensory nerve inactivation.
    Journal of musculoskeletal & neuronal interactions, 2014, Volume: 14, Issue:1

    Topics: Animals; Bone and Bones; Bone Development; Capsaicin; Mice; Mice, Inbred C57BL; Nerve Degeneration; Peripheral Nervous System Diseases; Sensory System Agents; Tomography, X-Ray Computed

2014
Assessment of the feasibility of high-concentration capsaicin patches in the pain unit of a tertiary hospital for a population of mixed refractory peripheral neuropathic pain syndromes in non-diabetic patients.
    BMC anesthesiology, 2014, Volume: 14

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics; Capsaicin; Feasibility Studies; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Prospective Studies; Tertiary Care Centers; Time Factors; Transdermal Patch; Treatment Outcome

2014
Successful treatment of refractory neuropathic pruritus with capsaicin 8% patch: a bicentric retrospective study with long-term follow-up.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antipruritics; Capsaicin; Female; France; Humans; Middle Aged; Peripheral Nervous System Diseases; Pruritus; Remission Induction; Retrospective Studies; Time Factors; Transdermal Patch; Treatment Outcome

2015
Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons.
    Experimental neurology, 2016, Volume: 279

    Topics: Animals; Antineoplastic Agents; Calcitonin Gene-Related Peptide; Capsaicin; Epothilones; Ganglia, Spinal; Male; Microtubules; Nerve Growth Factor; Neurites; Neuropeptides; Neurotransmitter Agents; Paclitaxel; Peripheral Nervous System Diseases; Potassium; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells

2016
Cost-Effectiveness of Capsaicin 8% Patch Compared with Pregabalin for the Treatment of Patients with Peripheral Neuropathic Pain in Scotland.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Administration, Topical; Analgesics; Capsaicin; Cost-Benefit Analysis; Humans; Peripheral Nervous System Diseases; Pregabalin; Scotland; Sensory System Agents

2016
Interleukin-1alpha regulates substance P expression and release in adult sensory neurons.
    Experimental neurology, 2009, Volume: 217, Issue:2

    Topics: Age Factors; Animals; Capsaicin; Cells, Cultured; Female; Ganglia, Spinal; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Nerve Growth Factor; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Substance P; Up-Regulation

2009
A new combination cream for the treatment of severe neuropathic pain.
    Journal of pain and symptom management, 2010, Volume: 39, Issue:2

    Topics: Administration, Topical; Analgesics; Capsaicin; Diabetic Neuropathies; Drug Combinations; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Ointments; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin

2010
Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in the spinal cord dorsal horn of rats with neuropathic and inflammatory pain.
    Journal of neurochemistry, 2010, Volume: 114, Issue:1

    Topics: Animals; Capsaicin; Glutamic Acid; Inflammation; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Posterior Horn Cells; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate

2010
Long-term safety of NGX-4010, a high-concentration capsaicin patch, in patients with peripheral neuropathic pain.
    Journal of pain and symptom management, 2010, Volume: 39, Issue:6

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Capsaicin; Female; HIV Infections; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain; Peripheral Nervous System Diseases; Treatment Outcome; Young Adult

2010
[Types of topical treatment for peripheral neuropathic pain : Mechanism of action and indications].
    Schmerz (Berlin, Germany), 2010, Volume: 24, Issue:4

    Topics: Administration, Topical; Afferent Pathways; Analgesics; Anesthetics, Local; Antidepressive Agents; Capsaicin; Humans; Lidocaine; Nerve Fibers; Nerve Regeneration; Neuralgia; Peripheral Nervous System Diseases; Sensory System Agents; TRPV Cation Channels

2010
Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat.
    Pain, 2011, Volume: 152, Issue:3

    Topics: Acetanilides; Analysis of Variance; Animals; Ankyrins; Calcium Channels; Capsaicin; Cholecystokinin; Cinnamomum zeylanicum; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Male; N-Methylaspartate; Pain Measurement; Peripheral Nervous System Diseases; Purines; Rats; Rats, Wistar; Sleep Deprivation; Spinal Cord; TRPA1 Cation Channel; TRPC Cation Channels

2011
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism.
    Pflugers Archiv : European journal of physiology, 2012, Volume: 463, Issue:4

    Topics: Acetanilides; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Drug Hypersensitivity; Glutathione; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Paclitaxel; Peripheral Nervous System Diseases; Purines; Pyrroles; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2012
A human model of small fiber neuropathy to study wound healing.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adult; Biopsy; Capsaicin; Epidermis; Humans; Nerve Fibers; Peripheral Nervous System Diseases; Skin; Wound Healing; Young Adult

2013
Effects of peripheral nerve injury on functional spinal VR1 receptors.
    Neuroreport, 2002, Jul-02, Volume: 13, Issue:9

    Topics: Action Potentials; Animals; Capsaicin; Denervation; Dose-Response Relationship, Drug; Down-Regulation; Hyperalgesia; Ligation; Nerve Fibers; Nerve Fibers, Myelinated; Neuralgia; Neuronal Plasticity; Nociceptors; Pain Threshold; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Physical Stimulation; Posterior Horn Cells; Rats; Receptors, Drug

2002
Enhanced release of adenosine in rat hind paw following spinal nerve ligation: involvement of capsaicin-sensitive sensory afferents.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Afferent Pathways; Animals; Capsaicin; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Male; Nerve Crush; Nerve Fibers, Unmyelinated; Neuralgia; Neurons, Afferent; Nociceptors; Oxidopamine; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Skin; Spinal Nerves; Sympathetic Fibers, Postganglionic

2002
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1

    Topics: Algorithms; Animals; Anticonvulsants; Capsaicin; Carbamazepine; Dose-Response Relationship, Drug; Guinea Pigs; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptors, Drug; Sciatic Nerve

2003
State-dependent phosphorylation of epsilon-isozyme of protein kinase C in adult rat dorsal root ganglia after inflammation and nerve injury.
    Journal of neurochemistry, 2003, Volume: 85, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Carrageenan; Disease Models, Animal; Diterpenes; Freund's Adjuvant; Ganglia, Spinal; Hindlimb; Hyperalgesia; Inflammation; Ligation; Male; Neurons; Nociceptors; Pain; Pain Measurement; Peripheral Nervous System Diseases; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Drug

2003
A thymulin analogue peptide with powerful inhibitory effects on pain of neurogenic origin.
    Neuroscience, 2003, Volume: 119, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Ligation; Male; Meloxicam; Morphine; Pain; Pain Threshold; Peptides; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Reaction Time; Thiazines; Thiazoles; Thymic Factor, Circulating; Time Factors

2003
Secondary tactile hypoesthesia: a novel type of pain-induced somatosensory plasticity in human subjects.
    Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3

    Topics: Adolescent; Adult; Afferent Pathways; Capsaicin; Female; Humans; Hypesthesia; Male; Mechanoreceptors; Middle Aged; Nerve Fibers, Unmyelinated; Neural Inhibition; Neuronal Plasticity; Neurons, Afferent; Nociceptors; Pain; Peripheral Nervous System Diseases; Presynaptic Terminals; Skin; Synaptic Transmission; Touch

2004
Neurogenic insulin resistance in guinea-pigs with cisplatin-induced neuropathy.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Acetylcholine; Animals; Antineoplastic Agents; Atropine; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Celiac Plexus; Cisplatin; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose Clamp Technique; Guinea Pigs; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Peripheral Nervous System Diseases; Vasodilator Agents

2006
Inhibitory M2 muscarinic receptors are upregulated in both axotomized and intact small diameter dorsal root ganglion cells after peripheral nerve injury.
    Neuroscience, 2006, Jun-19, Volume: 140, Issue:1

    Topics: Animals; Axotomy; Behavior, Animal; Bethanechol; Calcium; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Gallamine Triethiodide; Ganglia, Spinal; Immunohistochemistry; Male; Muscarinic Agonists; Neural Inhibition; Neurons; Nicotinic Antagonists; Peripheral Nervous System Diseases; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2

2006
Prevalence of somatic small fiber neuropathy in obesity.
    International journal of obesity (2005), 2007, Volume: 31, Issue:2

    Topics: Adult; Age Factors; Body Mass Index; Capsaicin; Cross-Sectional Studies; Female; Glucose Tolerance Test; Hot Temperature; Humans; Hyperglycemia; Hyperinsulinism; Male; Middle Aged; Nerve Fibers; Obesity, Morbid; Peripheral Nervous System Diseases; Reaction Time; Regional Blood Flow; Sensation Disorders; Skin; Transcutaneous Electric Nerve Stimulation

2007
Chili peppers, nerve regeneration, and clinical trial design.
    Neurology, 2007, Apr-17, Volume: 68, Issue:16

    Topics: Biomarkers; Biopsy; Capsaicin; Capsicum; Clinical Trials as Topic; Diabetic Neuropathies; HIV Infections; Humans; Nerve Fibers, Unmyelinated; Nerve Regeneration; Peripheral Nervous System Diseases; Sensory Receptor Cells; Treatment Outcome

2007
Impaired reinnervation in HIV infection following experimental denervation.
    Neurology, 2007, Apr-17, Volume: 68, Issue:16

    Topics: Adult; Analgesics, Non-Narcotic; Antiretroviral Therapy, Highly Active; Apolipoprotein E4; Biomarkers; Capsaicin; Denervation; Female; Genetic Predisposition to Disease; Genetic Testing; HIV Infections; Humans; Male; Nerve Regeneration; Peripheral Nervous System Diseases; Predictive Value of Tests; Sensory Receptor Cells; Skin

2007
Reduced pain behaviors and extracellular signal-related protein kinase activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor.
    Journal of neurochemistry, 2007, Volume: 102, Issue:5

    Topics: Animals; Behavior, Animal; Capsaicin; Cell Count; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; Ganglia, Spinal; Male; Membrane Potentials; Mice; Mice, Knockout; Neurons, Afferent; Pain; Pain Measurement; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Physical Stimulation; Platelet Membrane Glycoproteins; Reaction Time; Receptors, G-Protein-Coupled

2007
Comparison of cytokine expression profile during Wallerian degeneration of myelinated and unmyelinated peripheral axons.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Animals; Axotomy; Capsaicin; Chemokine CCL2; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Ectodysplasins; Interleukin-10; Interleukin-1beta; Interleukin-2; Interleukin-6; Leukemia Inhibitory Factor; Macrophages; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Schwann Cells; Up-Regulation; Wallerian Degeneration

2008
Enhancement of cutaneous nerve regeneration by 4-methylcatechol in resiniferatoxin-induced neuropathy.
    Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Catechols; Disease Models, Animal; Diterpenes; Drug Interactions; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Nerve Fibers, Unmyelinated; Nerve Regeneration; Neural Conduction; Neuroprotective Agents; Peripheral Nervous System Diseases; Reaction Time; Skin; Substance P; Ubiquitin Thiolesterase

2008
Local application of capsaicin alleviates mechanical hyperalgesia after spinal nerve transection.
    Neuroscience letters, 2008, Mar-15, Volume: 433, Issue:3

    Topics: Analgesics; Animals; Biomarkers; Calcitonin Gene-Related Peptide; Capsaicin; Cell Count; Denervation; Ganglia, Spinal; Hyperalgesia; Male; Nerve Degeneration; Neuralgia; Neurons, Afferent; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sensory System Agents; TRPV Cation Channels

2008
Cytosine arabinoside affects the heat and capsaicin receptor TRPV1 localisation and sensitivity in human sensory neurons.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Calcium; Capsaicin; Cell Division; Cell Membrane; Cell Survival; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Ganglia, Spinal; GAP-43 Protein; Humans; Ionomycin; Neurons, Afferent; Peripheral Nervous System Diseases; Sensory System Agents; Time Factors; TRPV Cation Channels

2008
Dissociated secondary hyperalgesia in a subject with a large-fibre sensory neuropathy.
    Pain, 1993, Volume: 53, Issue:2

    Topics: Adult; Capsaicin; Evoked Potentials; Humans; Hyperalgesia; Laser-Doppler Flowmetry; Male; Mechanoreceptors; Nerve Fibers; Neurons, Afferent; Nociceptors; Peripheral Nervous System Diseases

1993
Skin blood flow disturbances in the contralateral limb in a peripheral mononeuropathy in the rat.
    Neuroscience, 1996, Volume: 74, Issue:3

    Topics: Animals; Capsaicin; Cold Temperature; Electric Stimulation; Functional Laterality; Hindlimb; Lidocaine; Male; Nerve Fibers; Neurons, Afferent; Pain; Peripheral Nervous System Diseases; Rats; Rats, Inbred Lew; Regional Blood Flow; Sciatic Nerve; Skin; Spinal Cord; Time Factors; Ultrasonography, Doppler; Vasoconstriction; Vasodilation

1996
Peripheral CGRP release as a marker for neurogenic inflammation: a model system for the study of neuropeptide secretion in rat paw skin.
    Pain, 1997, Volume: 73, Issue:2

    Topics: Animals; Basal Metabolism; Biomarkers; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Hindlimb; Male; Nerve Endings; Neuritis; Neuropeptides; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Skin

1997
A novel procedure for mediastinal vagotomy inhibits neurogenic inflammation in rat bronchial tree.
    Journal of the autonomic nervous system, 1997, Dec-03, Volume: 67, Issue:1-2

    Topics: Animals; Axons; Bronchitis; Capillary Permeability; Capsaicin; Carbon; Coloring Agents; Evans Blue; Female; Mediastinum; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Recurrent Laryngeal Nerve; Vagotomy; Vagus Nerve

1997
Cholecystokinin-8 enhances nerve growth factor synthesis and promotes recovery of capsaicin-induced sensory deficit.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Male; Mice; Nerve Growth Factor; Neurons, Afferent; Pain Threshold; Peripheral Nervous System Diseases; RNA, Messenger; Sincalide; Substance P; Up-Regulation

2000
Influence of capsaicin cream in rats with peripheral neuropathy.
    Pharmacological research, 2001, Volume: 44, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Benzamides; Capsaicin; Carrageenan; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Indoles; Isoindoles; Male; Neuroprotective Agents; Pain; Peripheral Nervous System Diseases; Piperidines; Postoperative Period; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Substance Withdrawal Syndrome; Time Factors

2001
Capsaicin-sensitive primary afferents mediate responses to cold in rats with a peripheral mononeuropathy.
    Neuroreport, 2002, Mar-25, Volume: 13, Issue:4

    Topics: Animals; Cannabinoids; Capsaicin; Cold Temperature; Diterpenes; Hindlimb; Hyperalgesia; Ligation; Male; Mononeuropathies; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve

2002
Neurogenic hyperalgesia versus painful hypoalgesia: two distinct mechanisms of neuropathic pain.
    Pain, 2002, Volume: 96, Issue:1-2

    Topics: Adult; Aged; Capsaicin; Central Nervous System Diseases; Cold Temperature; Female; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Neuralgia; Neurons, Afferent; Pain Threshold; Peripheral Nervous System Diseases; Touch

2002
Experimental peripheral neuropathy decreases the dose of substance P required to increase excitatory amino acid release in the CSF of the rat spinal cord.
    Neuroscience letters, 1992, May-11, Volume: 139, Issue:1

    Topics: Amino Acids; Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Dialysis; Male; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Substance P

1992
Acrylamide-induced visceral neuropathy: evidence for the involvement of capsaicin-sensitive nerves of the rat urinary bladder.
    Neuroscience, 1991, Volume: 41, Issue:1

    Topics: Acrylamide; Acrylamides; Animals; Capsaicin; Male; Muscle, Smooth; Neurons, Afferent; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Urethra; Urinary Bladder; Urinary Retention

1991
Topical capsaicin therapy for neuropathic pain.
    Pain, 1991, Volume: 47, Issue:3

    Topics: Administration, Topical; Capsaicin; Humans; Pain; Peripheral Nervous System Diseases

1991
Measurement of flare responses in patients with pain.
    Clinical and experimental neurology, 1987, Volume: 24

    Topics: Adult; Aged; Capsaicin; Chronic Disease; Female; Humans; Male; Middle Aged; Nociceptors; Pain; Pain Measurement; Peripheral Nervous System Diseases

1987