capsaicin has been researched along with Innate Inflammatory Response in 397 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (5.29) | 18.7374 |
1990's | 98 (24.69) | 18.2507 |
2000's | 141 (35.52) | 29.6817 |
2010's | 100 (25.19) | 24.3611 |
2020's | 37 (9.32) | 2.80 |
Authors | Studies |
---|---|
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
Aprile, S; Butron, L; Devesa, I; Fernandez-Carvajal, A; Ferrer-Montiel, A; Genazzani, AA; Gonzalez-Rodriguez, S; Griglio, A; Grosa, G; Pattarino, F; Pirali, T; Seiti, F; Serafini, M; Sorba, G; Travelli, C | 1 |
Doble, M; Manju, SL; Sinha, S | 1 |
Bang, SK; Cho, SJ; Choi, KH; Kang, SY; Ryu, Y; Seo, SY | 1 |
Cheng, N; Cheng, X; Ling, J; Liu, H; Ruan, Y; Tang, Z; Wu, F; Ye, F | 1 |
Chatthanathon, P; Leelahavanichkul, A; Panpetch, W; Saisorn, W; Sawatpanich, A; Somboonna, N; Tumwasorn, S; Visitchanakun, P | 1 |
Chen, X; Munjuluri, S; Obukhov, AG; Sooch, G; White, FA; Wilkerson, DA | 1 |
Frederick, KA; Gaetgens, J; Giuriato, G; Ives, SJ; Matias, A; Soares, EMKVK; Venturelli, M | 1 |
Lei, F; Yan, Z | 1 |
Calzetta, L; Cito, G; Pistocchini, E; Ritondo, BL; Rogliani, P; Verri, S | 1 |
Anders, B; Anders, M; Behrens, F; Fricker, L; Köhm, M; Kreuzer, M; Maier, C; Walter, C; Wolters, M; Zinn, S | 1 |
Guan, L; Li, J; Zhang, X | 1 |
Li, J; Liu, D; Ma, C; Wang, G; Zhang, Z; Zhong, X | 1 |
Chen, J; Dai, L; Gu, L; Li, Z; Liao, F; Liu, D; Liu, Y; Luo, P; Tang, H; Wang, J; Xia, F; Xu, C; Yang, F; Zhang, J; Zhang, Q; Zheng, L; Zhu, Y | 1 |
Boonthip, C; Den-Udom, T; Ketsawatsomkron, P; Laolob, T; Muta, K; Sibmooh, N; Sriwantana, T; Thongin, S; Uppakara, K; Wichai, U | 1 |
Asadzadeh Aghdaei, H; Azimirad, F; Azimirad, M; Gholami, F; Naseri, K; Noori, M; Yadegar, A; Zali, MR | 1 |
Chen, Q; Lai, K; Li, H; Liu, B; Luo, W; Peng, W; Tang, J; Yi, F; Zhan, C; Zhou, J | 1 |
Cheng, Y; Deng, Q; Fang, Z; Hu, L; Sun, D; Sun, L; Wang, C; Yang, B; Zhao, J | 1 |
Bliss, E; Mills, D; Thornton, T | 1 |
Abdalla, M; Aldosari, SM; Alshehri, B; El-Arabey, AA; Eltayeb, WA; Khan, J; Rakshit, G; Rudrapal, M | 1 |
Huang, CJ; Lee, CH; Lo, SL; Pu, CM; Su, SY; Yen, YH | 1 |
Helyes, Z; Szőke, É | 1 |
Guo, J; Song, Y; Tang, J; Tang, Z; Yang, Y; Yu, G; Zhu, C | 1 |
Koga, K; Uta, D; Yoshimura, M | 1 |
B T, P; Belenahalli Shekarappa, S; G S, PK; H Malojirao, V; Hanumanthappa, M; Kandagalla, S | 1 |
Artico, M; Giacomoni, C; Lattanzi, R; Maftei, D; Severini, C; Vellani, V | 1 |
Gerstberger, R; Leisengang, S; Murgott, J; Nürnberger, F; Ott, D; Roth, J; Rummel, C; Schmidt, M | 1 |
Bansal, Y; Bishnoi, M; Khare, P; Kondepudi, KK; Kuhad, A; Medhi, B; Singh, R; Sodhi, RK | 1 |
Cabeça, LF; Costa, JSR; Couto, VM; Franco, MKKD; Franz-Montan, M; Geraldes, DC; Oliveira-Nascimento, L; Paula, E; Riske, KA; Yokaychiya, F | 1 |
Aguilera-Lizarraga, J; Alpizar, YA; Berg, M; Boeckxstaens, G; De Man, JG; De Winter, B; Florens, MV; Hanning, N; Jain, P; Perna, E; Talavera, K; Theofanous, SA; Vanden Berghe, P; Wouters, M | 1 |
Koch, M; Messlinger, K; Sertel-Nakajima, J | 1 |
Iesanu, MI; Paslaru, AC; Rosca, AE; Voiculescu, SE; Zagrean, AM; Zahiu, CDM | 1 |
Bach, H; Carranza, A; Gorzalczany, SB; Rodríguez Basso, A; Zainutti, VM | 1 |
Ali, M; Basharat, A; Basharat, S; Gilani, SA; Iftikhar, F; Murtaza, MA; Qamar, MM; Sattar, A | 1 |
Ballester, GF; Butron, L; Devesa, I; Fernández-Carvajal, A; Ferrer-Montiel, A; Genazzani, AA; González-Rodríguez, S; Nikolaeva-Koleva, M; Pirali, T; Serafini, M; Valente, P | 1 |
Alhouayek, M; Ben Kouidar, Y; Buisseret, B; Guillemot-Legris, O; Muccioli, GG; Paquot, A | 1 |
Belboukhari, N; Cheriti, A; Ould El Hadj-Khelil, A; Seddiki, LS; Sekkoum, K; Sulaiman, MR | 1 |
Ballegaard, AR; Bøgh, KL; Larsen, JM; Pilegaard, K; Rasmussen, PH; Untersmayr, E | 1 |
Abd Al Haleem, EN; Arafa, HMM; Hasan, WYS | 1 |
An, N; Gao, Q; Li, J; Ni, W; Wang, H; Yu, Y; Zhang, L | 1 |
Aguilera, M; Cryan, JF; Fanning, A; Felice, VD; Grady, F; Hickey, A; McCarthy, L; Melgar, S; Moloney, A; Nally, K; O'Mahony, SM; Pawley, L; Rossini, V; Shanahan, F; Simnica, D | 1 |
Arulsamy, N; Baskaran, M; Baskaran, P; Thyagarajan, B | 1 |
Chen, M; Huang, L; Hui, S; Kaliannan, K; Kang, C; Lang, H; Mi, M; Wang, B; Wang, X; Zhang, Y; Zhou, M | 1 |
Cull-Candy, SG; Farrant, M; Sullivan, SJ | 1 |
Caruntu, C; Constantin, C; Georgescu, SR; Ilie, MA; Matei, C; Neagu, M; Sârbu, MI; Tampa, M | 1 |
Jones, KS; Truong, T | 1 |
Atmaramani, R; Black, BJ; Campbell, ZT; Dussor, G; Kumaraju, R; Pancrazio, JJ; Plagens, S; Price, TJ; Romero-Ortega, M | 1 |
Gu, Y; Huang, LM; Li, G | 1 |
Ma, S; Wang, DH; Yu, SQ | 1 |
Callejo, G; Chakrabarti, S; Hockley, JRF; Pattison, LA; Singhal, K; Smith, ESJ | 1 |
Barik, A; Bharucha-Goebel, D; Bönnemann, CG; Bushnell, MC; Case, L; Chesler, AT; Donkervoort, S; Foley, AR; Ghitani, N; Gordon, T; Lam, R; Liljencrantz, J; Necaise, A; Saade, D; Szczot, M; Thompson, JH | 1 |
Abdelaziz, R; Barry, AM; Gomez-Varela, D; Jahn, O; Kügler, S; Michel, N; Schmidt, M; Sondermann, JR | 1 |
Baudouin, C; Ben-Dhaou, C; Melik Parsadaniantz, S; Ouimet, T; Poras, H; Reaux-Le Goazigo, A; Wurm, M | 1 |
Adamante, G; Bellinaso, F; Camponogara, C; Casoti, R; Coelho, YO; da Silva Silveira, E; de Almeida, AS; De Prá, SD; Desideri, AV; Ferreira, J; Milioli, AM; Oliveira, SM; Rigo, FK; Santos, MFC; Trevisan, G | 1 |
Aghajani, M; Amani, A; Esmaeli, F; Faramarzi, MA; Ghazi-Khansari, M; Ghiasi, Z | 1 |
Duan, W; Fang, Y; Ma, C; Xie, Y; Zhu, J | 1 |
Bjerrum, OJ; Dalbøge, LS; Dupont, E; Heegaard, AM; Jensen, TS; Larsen, M; Møller, AT; Møller, LB; Nasser, A | 1 |
Buelow, DR; Konkel, ME; Neal-McKinney, JM; Riley, TP; Simasko, SM | 1 |
Baeyens, JM; Cobos, EJ; Entrena, JM; García-Granados, A; Nieto, FR; Parra, A | 1 |
Chen, HS; Li, FP; Li, XQ; Lin, Q; Liu, BJ; Qu, F; Wang, Y; Wen, WW | 1 |
Borghi, SM; Carvalho, TT; Casagrande, R; Hohmann, MS; Pinge-Filho, P; Staurengo-Ferrari, L; Verri, WA | 1 |
Dolan, S; Goldie, M | 1 |
Córdova, MM; Montrucchio, DP; Santos, AR | 1 |
Ching, LC; Kou, YR; Lee, TS; Lin, SJ; Shyue, SK; Wei, J; Zhao, JF | 1 |
Bhatnagar, A; Billeter, AT; Hellmann, JL; Polk, HC | 1 |
Dvorakovskaya, IV; Fedin, AN; Kuzubova, NA; Lebedeva, ES; Titova, ON | 1 |
Jolayemi, AT; Ojewole, JA | 1 |
Alhelal, MA; Letourneau, R; Palaska, I; Panagiotidou, S; Theoharides, TC | 1 |
Andreev, YA; Bondarenko, DA; Dyachenko, IA; Grishin, EV; Kabanova, NV; Kolesnikov, SS; Korolkova, YV; Kotova, PD; Kozlov, SA; Murashev, AN; Rogachevskaja, OA; Skobtsov, DI | 1 |
Almeida, FR; Amaral, MP; Chaves, MH; Costa, DA; Figueiredo, KA; Júnior, FB; Oliveira, FA; Oliveira, IS; Oliveira, RC; Silva, FV | 1 |
Dickie, AC; Torsney, C | 1 |
Doods, H; Gorham, L; Just, S | 1 |
Amaral, LS; Barreiro, EJ; Fraga, CA; Guimaraes, MZ; Lacerda, RB; Lima, CK; Miranda, AL; Quintas, LE; Santos, BL; Silva, RM; Silva, RV | 1 |
Fürst, R; Zündorf, I | 1 |
Abramson, L; Aoki-Nonaka, Y; Bertin, S; Corr, M; de Jong, PR; Dong, H; Franco, A; Fu, G; González-Navajas, JM; Gwack, Y; Han, T; Herdman, S; Jefferies, WA; Lee, J; Li, X; Nohara, LL; Raz, E; Srikanth, S; Stanwood, SR; To, K; Touma, R; Xu, H; Yu, T | 1 |
Basrur, V; Gowda, LR; Joe, B; Lokesh, BR; Nagaraju, A | 1 |
Kress, M; Langeslag, M; Leitner, MG; Mair, N; Quarta, S | 1 |
Albers, KM; Gold, MS; Zhang, XL | 1 |
Guindon, J; Lin, JS | 1 |
Boakye, CH; Godugu, C; Mendonca Faria, HA; Patel, AR; Singh, M; Somagoni, J; Zucolotto, V | 1 |
Kumamoto, N; Shibata, Y; Ueda, T; Ugawa, S; Watanabe, M | 1 |
Matoba, M; Minami, K; Miyano, K; Murakami, S; Ohbuchi, K; Shiraishi, S; Uezono, Y; Yamaguchi, T; Yamamoto, M; Yokoyama, T | 1 |
Binkowski, M; Czaja, M; Di Marzo, V; Kolosowska, N; Makuch, W; Malek, N; Morera, E; Mrugala, M; Przewlocka, B; Starowicz, K | 1 |
Bertin, S; Raz, E | 1 |
Cai, J; Kong, JG; Liao, FF; Liu, FY; Wan, Y; Xiao, X; Xing, GG; Xu, LC; Yi, M; Yue, LP; Zhao, XT | 1 |
Chen, C; Fan, F; Lin, C; Liu, Y; Liu, Z; Lu, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zhao, L; Zhu, P; Zhu, Z | 1 |
Bogdanov, Y; Crow, M; Denk, F; Grant, AD; Kelleher, JH; Khovanov, N; McMahon, SB; Sharma, S; Wood, JN | 1 |
Gan, YH; Hao, T; Kou, XX; Ma, XC; Wu, YW | 1 |
He, LL; Jiao, HY; Li, PB; Liao, Y; Su, WW; Zhou, Q; Zhu, N | 1 |
Jiang, Y; Lai, R; Lv, HN; Sun, XY; Wang, K; Wei, NN; Wu, Y; Yang, SL | 1 |
Belmonte, C; de la Peña, E; Ferrer-Montiel, A; Gomis, A | 1 |
Davletov, B; Ferrari, E; Geranton, SM; Hunt, SP; Leese, C; Maiarú, M; Mangione, AS; Obara, I; Tassorelli, C | 1 |
Bradshaw, H; Carey, LM; Cornett, B; Hohmann, AG; Leishman, E; Mackie, K; Slivicki, RA | 1 |
Gao, JJ; Guo, FX; Hu, YW; Huang, C; Kang, CM; Li, P; Lu, JB; Ma, X; Qiu, YR; Sha, YH; Wang, Q; Wang, YC; Xiu, JC; Xu, BM; Zhang, Y; Zhao, JJ; Zheng, L | 1 |
Kaur, CD; Mazumder, B; Sarwa, KK; Suresh, PK | 1 |
Frias, B; Merighi, A | 1 |
Kim, JM; Park, K; Shin, YH | 1 |
Babes, A; Becker, C; Engel, MA; Khalil, M; Kistner, K; Neurath, MF; Reeh, PW; Selescu, T; Siklosi, N; Wirtz, S; Zimmermann, K | 1 |
Finn, DP; Lenihan, R; Madasu, MK; Okine, BN; Olango, WM; Rea, K; Roche, M | 1 |
Aboushousha, R; Altier, C; Basso, L; Flynn, R; Iftinca, M; Melo, H; Taylor, L | 1 |
Coderre, TJ; Ding, S; Gyawali, S; Laferrière, A; Mahboubi, H; Mickeviciute, A; Nasir, H; Ragavendran, JV; Stochaj, U | 1 |
Berta, T; Bey, AL; Chang, W; Han, Q; Ji, RR; Jiang, YH; Kim, YH; Lay, M; Liu, D; Wang, X; Zhang, Y; Zhang, ZJ | 1 |
Andersen, HH; Arendt-Nielsen, L; Elberling, J | 1 |
Amuzescu, B; Caruntu, C; Deftu, A; Filippi, A; Gheorghe, RO; Ristoiu, V | 1 |
Gu, Q; Qu, C; Xu, Y | 1 |
Chen, Y; Han, JS; Li, GX; Li, T; Liu, FY; Luo, H; Shi, YS; Wan, Y; Xing, GG; Xu, IS; Yang, F; Yu, L | 1 |
Eijkelkamp, N; Elsenbruch, S; Heijnen, CJ; Holtmann, G; Kavelaars, A; Schedlowski, M | 1 |
Ballard, A; Bishop, T; Holmes, H; McMahon, SB; Young, AR | 1 |
Fang, L; Li, D; Lin, Q; Wang, P; Xu, X; Zou, X | 1 |
Brookes, SJ; Chen, BN; Costa, M; Lynn, PA; Zagorodnyuk, VP | 1 |
Arpino, S; Biggs, J; Coleman, T; Cryan, JE; Davis, JB; Gunthorpe, MJ; Holland, V; Jerman, JC; Lappin, SC; Medhurst, SJ; Mitchell, DJ; Rami, HK; Seal, JT; Stemp, G; Stevens, AJ; Thompson, M; Trouw, LS; Westaway, SM; Winborn, KY; Wright, J | 1 |
Huang, J; Wang, W | 1 |
García-López, BE; Granados-Soto, V; Herrejon-Abreu, EB; López-Santillán, FJ; Murbartián, J; Rocha-González, HI | 1 |
Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Vale, ML | 1 |
Cheng, TL; Hsu, KS; Huang, HT; Lam, HC; Lin, CJ; Liu, GS; Liu, LF; Shi, JY; Tai, MH; Tseng, RT; Wen, ZH; Weng, WT | 1 |
Adler, JE; Skoff, AM; Zhao, C | 1 |
Kang, JH; Kim, CS; Yu, R | 1 |
Bortolatto, CF; Jesse, CR; Nogueira, CW; Savegnago, L; Wilhelm, EA | 1 |
Goto, T; Han, IS; Kang, JH; Kawada, T; Kim, YM; Yu, R | 1 |
Verkman, AS; Zhang, H | 1 |
Fang, L; Gong, K; Li, D; Lin, Q; Wang, P; Xu, X; Zou, X | 1 |
Jeon, MS; Kim, BD; Kim, JH; Kim, TY; Kwon, YG; Lee, EJ; Lee, H; Lee, YS; Yang, JH | 1 |
Bettoni, I; Comelli, F; Costa, B; Di Marzo, V; Giagnoni, G; Petrosino, S | 1 |
Bakthavatchalam, R; Blum, CA; Boyce, S; Brielmann, H; Burnaby-Davies, N; Caldwell, T; Capitosti, S; Chenard, BL; Conley, R; Cortright, D; Crandall, M; De Lombaert, S; Hodgetts, KJ; Jones, AB; Kershaw, MT; Krause, JE; Martin, WJ; Mason, G; Matson, D; Murphy, BA; Perrett, H; Rycroft, W; Zheng, X | 1 |
Coderre, TJ; Kumar, N; Laferriere, A; Poon, T; Yu, JS | 1 |
Buurman, WA; de Haan, JJ; Dejong, CH; Greve, JW; Hadfoune, M; Lubbers, T; Luyer, MD; Verbaeys, I | 1 |
Al-Khrasani, M; Brendl, U; Fürst, S; Mousa, SA; Schäfer, M; Shaqura, M | 1 |
Bunch, J; Jajoo, S; Kaur, T; Mukherjea, D; Perro, C; Ramkumar, V; Rybak, LP; Sheehan, K; Sheth, S | 1 |
Bai, ZT; Cheng, M; Hua, LM; Ji, YH; Jiang, F; Liu, T; Pang, XY; Shi, J; Shu, XQ; Zhang, JW; Zhou, JJ | 1 |
Drummond, PD; Knudsen, L | 1 |
Hayes, D; Lee, LY; Lin, RL; Ni, D | 1 |
Andrade, EL; Calixto, JB; Rogerio, AP | 1 |
Benoit, M; Chen, X; Gudermann, T; Hofmann, T; Janssens, A; Kerselaers, S; Nilius, B; Oberwinkler, J; Owsianik, G; Philipp, SE; Stab, J; Vennekens, R; Voets, T; Vriens, J; Xue, F | 1 |
Bang, S; Cho, H; Hwang, SW; Yang, TJ; Yoo, S | 1 |
Ji, W; Liang, J; Xiao, G | 1 |
Holstege, JC; Hossaini, M; Jongen, JL; Saraç, C | 1 |
Barbosa, S; Fernández-Blanco, JA; Martínez, V; Sánchez de Medina, F; Vergara, P | 1 |
Ang, SF; Bhatia, M; MacAry, PA; Moochhala, SM | 1 |
Deering-Rice, CE; Dull, RO; Lee, J; Reilly, CA; Roberts, JK; Romero, EG; Thomas, KC; Yost, GS | 1 |
Canetta, SE; Luca, E; Pertot, E; Role, LW; Talmage, DA | 1 |
Daugherty, D; Dykstra, LA; Henry, FE; Miller, LL; Picker, MJ | 1 |
Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M | 1 |
Henry, PJ; Mann, TS; Taylor, SJ | 1 |
Jia, MM; Li, XJ; Li, YS; Liu, M; Tang, HB; Wang, JX | 1 |
Endo, T; Inagaki, N; Nagai, H; Saito, A; Shimouchi, A; Tanaka, H; Tominaga, M; Usuda, H; Yamashita, H | 1 |
Honda, K; Iwata, K; Okada-Ogawa, A; Shinoda, M | 1 |
Dolan, S; Graham, A; Iannitti, T | 1 |
Comelli, F; Costa, B; D'Agostino, B; de Novellis, V; De Petrocellis, L; Di Marzo, V; Gatta, L; Guida, F; Luongo, L; Maione, S; Matteis, M; Sullo, N | 1 |
Fereidoni, M; Niazmand, S; Sepehri, Z | 1 |
Honda, K; Iwata, K; Katagiri, A; Matsuura, S; Ogiso, B; Ohara, K; Sessle, BJ; Shimizu, K; Shinoda, M; Urata, K | 1 |
Casey, KL; Cross, DJ; Lorenz, J; Minoshima, S; Morrow, TJ; Paulson, PE | 1 |
Cai, Y; Evensjö, M; Kovács, KJ; Larson, AA; McCarson, KE; Shi, Q; Velázquez, RA | 1 |
Braun, A; Hoyle, GW; Kerzel, S; Meents, N; Nockher, WA; Päth, G; Quarcoo, D; Raap, U; Renz, H | 1 |
Fox, AJ; McIntyre, P; Medhurst, SJ; Panesar, M; Patel, S; Urban, L; Walker, KM | 1 |
Carr, MJ; Undem, BJ | 1 |
Bayer, MK; Chavolla-Calderón, M; Fontán, JJ | 1 |
Li, GD; Zhao, ZQ; Zhou, Y | 1 |
Bristol, DR; Harrison, JE; Mark, L; Pomonis, JD; Valenzano, KJ; Walker, K | 1 |
Carr, BA; Crouch, DJ; Lanza, DL; Reilly, CA; Taylor, JL; Yost, GS | 1 |
Hamamoto, DT; Hodges, JS; Maccecchini, ML; Simone, DA; Turner, MS | 1 |
Gábor, M | 1 |
Al-Chaer, ED; Kawasaki, M | 1 |
Davies, C; Harrison, NK; Hilldrup, S; Hope-Gill, BD; Newton, RP | 1 |
Gustafsson, H; Hole, K; Kjørsvik Bertelsen, A; Stiller, CO; Tjølsen, A; Warsame Afrah, A | 1 |
Fang, L; Lin, Q; Willis, WD; Wu, J | 2 |
Bueno, L; Bunnett, NW; Cenac, N; Coelho, AM; Compton, SJ; Garcia-Villar, R; Grady, E; Hollenberg, MD; Nguyen, C; Steinhoff, M; Vergnolle, N; Wallace, JL | 1 |
Boyle, DL; Firestein, GS; Moore, J; Sorkin, LS; Yang, L | 1 |
Green, PG; Levine, JD; Miao, FJ | 1 |
Fang, L; Lin, Q; Ren, Y; Wang, J; Willis, WD; Zou, X | 1 |
Bánvölgyi, A; Brain, SD; Ghosh, M; Helyes, ZS; Melegh, B; Pintér, E; Pozsgai, G; Szolcsányi, J | 1 |
Baamonde, A; Hidalgo, A; Lastra, A; Menéndez, L | 1 |
Cortright, DN; Szallasi, A | 1 |
Baamonde, A; Fresno, MF; Hidalgo, A; Lastra, A; Llames, S; Meana, A; Menéndez, L | 1 |
Drummond, PD | 1 |
Carlton, SM; Castañeda-Hernandez, G; Du, J; Grady, JJ; Jimenez-Andrade, JM; Yamani, A; Zhou, S | 1 |
Colleoni, M; Costa, B; Franke, C; Giagnoni, G; Trovato, AE | 1 |
Clapham, DE; Ji, RR; Xu, H; Zhuang, ZY | 1 |
Higashi, T; Iida, T; Moriyama, T; Murayama, N; Numazaki, M; Togashi, K; Tominaga, M; Tominaga, T | 1 |
Jones, CK; Peters, SC; Shannon, HE | 1 |
Bayraktar, M; Bayraktar, N; Demirbilek, S; Ersoy, MO; Gürbüz, N; Karaman, A | 1 |
Bonebreak, DB; Flake, NM; Gold, MS | 1 |
Arata, V; Kasahara, DI; Leick-Maldonado, EA; Martins, MA; Prado, CM; Tibério, IF | 1 |
Bannon, AW; Doherty, EM; Gavva, NR; Immke, D; Klionsky, L; Louis, JC; Norman, MH; Porreca, F; Qu, Y; Tamir, R; Treanor, JJ; Vanderah, TW; Wang, J; Wild, KD; Zhang, TJ; Zhu, D | 1 |
Ko, S; Qiu, CS; Toyoda, H; Zhao, MG; Zhuo, M | 1 |
Tominaga, M | 1 |
Caterina, M; Cowan, A; Inan, S; Oppenheim, JJ; Rogers, TJ; Sun, R; Wang, JM; Zhang, N | 1 |
Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S | 1 |
Amadesi, S; Dinh, QT; Fischer, A; Geppetti, P; Groneberg, DA; Harrison, S; Lencer, D; Maggiore, B; Peiser, C; Trevisani, M | 1 |
Breese, NM; George, AC; Pauers, LE; Stucky, CL | 1 |
El Kouhen, R; Faltynek, CR; Gauvin, DM; Gomtsyan, A; Honore, P; Jarvis, MF; Lee, CH; Marsh, K; Mikusa, J; Sullivan, JP; Wismer, CT; Zhong, C; Zhu, CZ | 1 |
Carini, F; Messina, P; Scardina, GA | 1 |
Breuer, A; Fride, E; Hanus, L; Ponde, D | 1 |
Cairns, BE; Hu, JW; Lam, DK; Sessle, BJ | 1 |
Camerer, E; Coughlin, SR; Hamilton, JR; Matthay, MA; Su, X | 1 |
Carlton, SM; Castañeda-Hernandez, G; Jimenez-Andrade, JM; Valencia de Ita, S; Yamani, A; Zhou, S | 1 |
Ahern, GP; O'Connell, PJ; Pingle, SC | 1 |
Compte, L; De Diego, A; Macián, V; Martínez, E; Nieto, L; Perpiñá, M; Senent, L | 1 |
Brozmanova, M; Hutka, Z; Pecova, R; Petriskova, J; Raffajova, J; Tatar, M; Zucha, J | 1 |
Kostina, NE; Spiridonov, VK | 2 |
Baamonde, A; Hidalgo, A; Juarez, L; Lastra, A; Menéndez, L | 1 |
Baamonde, A; García, E; García-Suárez, O; Hidalgo, A; Juárez, L; Menéndez, L | 1 |
Abbadi, N; Ase, A; Breese, NM; Mogil, JS; Rainville, ML; Ritchie, J; Séguéla, P; Stucky, CL; Witty, MF | 1 |
Brain, SD; Costa, SK; Muscará, MN; Poston, RN; Yshii, LM | 1 |
Hohmann, AG; Nackley, AG; Neely, MH; Piña, J | 1 |
Fu, Y; Kochukov, MY; McNearney, TA; Westlund, KN | 1 |
Beitz, AJ; Choi, SM; Han, HJ; Kang, SY; Kim, HW; Kim, KW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Ryu, YH; Yoon, SY | 1 |
Arendt-Nielsen, L; Chen, HS; Graven-Nielsen, T; He, X; Lei, J; Wang, Y; Wei, XZ; Wen, WW; You, HJ | 1 |
Amadesi, S; Andre, E; Bunnett, NW; Dinh, TQ; Fischer, A; Gatti, R; Geppetti, P; Harrison, S; Trevisani, M | 1 |
Carlton, SM; Ji, GC; Jurczyk, S; Reubi, JC; Shapiro, G; Zhou, ST | 1 |
Castañeda-Hernandez, G; Lawand, NB; Lin, Q; Valencia-de Ita, S; Willis, WD | 1 |
Chang, SY; Ho, CY; Kou, YR; Tsai, TL | 1 |
Cabot, PJ; Hermanussen, S; Kapitzke, D; Monteith, GR; Vetter, I | 1 |
Fujimura, M; Liu, Q | 1 |
Harada, N; Okajima, K | 1 |
Manjunatha, H; Srinivasan, K | 1 |
Amaya, F; Barrett, L; Lin, CR; Samad, TA; Takada, J; Wang, H; Woolf, CJ | 1 |
Belmonte, C; Carreño, C; Fernández-Carvajal, A; Ferrer-Montiel, A; Ferroni, S; García-Martínez, C; Gomis, A; Valenzuela, B; Van Den Nest, W | 1 |
Chabot, JG; Ma, W; Quirion, R | 1 |
Amadesi, S; Bunnett, N; Hu, WP; Li, JD; Luo, ZD; Zhang, C; Zhou, QY | 1 |
Bolser, DC; Brown, D; Chen, J; Fernandez, X; Hey, JA; Jia, Y; Kreutner, W; McHugh, NA; McLeod, RL; Mingo, GG; Parra, LE; Wang, X | 1 |
Colleoni, M; Comelli, F; Costa, B; Giagnoni, G; Trovato, AE | 1 |
Afifiyan, FN; Chan, Y; Dosch, HM; Driver, JP; Liu, XJ; Razavi, R; Salter, MW; Santamaria, P; Serreze, D; Tang, L; Tsai, S; Tsui, H; Wan, X; Yantha, J | 1 |
Barrett, AC; Lomas, LM; Lysle, DT; Picker, MJ; Terner, JM | 1 |
Börzsei, R; Elekes, K; Helyes, Z; Kereskai, L; Németh, J; Pintér, E; Pozsgai, G; Sándor, K; Szabó, A; Szolcsányi, J | 1 |
Bianchi, R; Borsani, E; Labanca, M; Rodella, LF | 1 |
Brandt, MR; Colburn, RW; D'Andrea, MR; Flores, CM; Lawrence, D; Liu, Y; Lubin, ML; Qin, N; Stone, DJ; Wang, Y | 1 |
Atkinson, R; Carroll, W; Chapman, M; Chu, K; Drizin, I; Faltynek, CR; Gauvin, D; Gregg, R; Gross, M; Hakeem, A; Hernandez, G; Honore, P; Jarvis, MF; Johnson, M; Joshi, S; Kort, M; Krafte, DS; Krambis, M; Liu, D; Liu, Y; Marron, B; Marsh, K; Matulenko, M; McGaraughty, S; Mikusa, JP; Pai, M; Roeloffs, R; Scanio, M; Shi, L; Shieh, CC; Sullivan, JP; Thomas, J; Wade, C; Wagoner, PK; Zhang, XF; Zhong, C; Zhu, C | 1 |
Gyires, K; Helyes, Z; László, J; Sándor, K; Szolcsányi, J | 1 |
Amadesi, S; Bunnett, NW; Chapman, K; Cottrell, GS; Gedda, K; Hollenberg, MD; Knecht, W; Mohlin, J; Peterson, A; Skåregärde, A; Vergnolle, N | 1 |
Bagoly, T; Börzsei, R; Elekes, K; Helyes, Z; Márk, L; Németh, J; Pintér, E; Pozsgai, G; Reglodi, D; Szolcsányi, J; Tóth, G | 1 |
Brain, SD; Kofler, B; Schmidhuber, SM; Starr, A; Wynick, D | 1 |
Fujimura, M; Hara, J; Kasahara, K; Kita, T; Myou, S; Ohkura, N; Oribe, Y; Ueda, A; Yasui, M | 1 |
Abu-Asab, M; Iadarola, MJ; Jenkins, AC; Karai, LJ; Mannes, AJ; Neubert, JK; Zawatski, L | 1 |
Ahmadi, S; Brockhaus, J; Brune, K; Fritschy, JM; Hess, A; Hösl, K; Knabl, J; Möhler, H; Reinold, H; Rudolph, U; Sergejeva, M; Witschi, R; Zeilhofer, HU; Zeilhofer, UB | 1 |
Brand, A; Erdmann, B; Heppenstall, PA; Hu, J; Jüttner, R; Laurito, CE; Lewin, GR; Lu, Y; Milenkovic, N; Park, TJ; Smith, ES; Wetzel, C; Wilson, SP | 1 |
Hernández, E; Rudomin, P | 1 |
Grau, JW; Hook, MA; Huie, JR | 1 |
Gold, MS; Lu, SG | 1 |
Alves, MK; Carvalho, TA; Cunha, FQ; de Oliveira, JR; Leite, CE; Lunardelli, A; Poloni, JA; Spiller, F; Vieira, SM | 1 |
Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y | 1 |
Anggård, A; Lundberg, JM; Lundblad, L; Martling, CR | 1 |
Colpaert, FC; Donnerer, J; Lembeck, F | 1 |
Jancśo, G; Jancsó-Gábor, A; Király, E | 1 |
Cruwys, SC; Garrett, NE; Kidd, BL | 1 |
Cambridge, H | 1 |
Bennett, DL; McMahon, SB; Priestley, JV; Shelton, DL | 1 |
Bartoshuk, L; Berger, A; Cooper, D; Duffy, V; Henderson, M; Nadoolman, W; Saberski, L | 1 |
Blanchard, JC; Carruette, A; Garret, C; Laduron, PM; Montier, F; Moussaoui, SM | 1 |
Desai, MC; Hoffman, JI; Husseini, WK; Nadel, JA; Piedimonte, G; Snider, RM | 1 |
Garret, C; Le Prado, N; Moussaoui, SM; Philippe, L | 1 |
Handwerker, HO; Ringkamp, M; Schmelz, M; Schmidt, R; Torebjörk, HE | 1 |
Dubner, R; Ren, K; Ruda, MA; Williams, GM | 1 |
Castro-Lopes, JM; Coimbra, A; Tavares, I; Tölle, TR | 1 |
Amico-Roxas, M; Caruso, A; Catena Cutuli, VM; Clementi, G; de Bernardis, E; Maugeri, S; Prato, A; Scapagnini, U | 1 |
Boyer, V; D'Ortho, MP; Harf, A; Jarreau, PH; Macquin-Mavier, I | 1 |
Dow, RC; Fink, G; Hopkins, SJ; Rothwell, NJ; Turnbull, AV; White, A | 1 |
Frevert, CW; Long, NC; Shore, SA | 2 |
Bertrand, C; Foresi, A; Geppetti, P; Graf, PD; Nadel, JA | 1 |
Arbetter, K; Leff, AR; Mitchell, RW; Ndukwu, IM; Solway, J | 1 |
Berman, EF; Buckwalter, BL; Farmer, RW; Janusz, JM; Kasting, GB; Kerckaert, GA; LaHann, TR; Loomans, ME; Maddin, CS; Young, PA | 1 |
Everaert, E; Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA | 1 |
Spiridonov, VK; Zhukova, EM | 1 |
Philip, G; Sanico, AM; Togias, A | 1 |
Baluk, P; Bowden, JJ; Lefevre, PM; Lindsey, JR; McDonald, DM; Schoeb, TR | 1 |
Blake, DR; Brain, SD; Cambridge, H; Kerslake, S; Mapp, PI | 1 |
Ceserani, R; Dalla Rosa, C; Gallico, L; Oggioni, N; Tognella, S | 1 |
Hu-Tsai, M; Winter, J; Woolf, C | 1 |
Lynn, B; Pierau, FK; Schütterle, S | 1 |
Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH | 1 |
Alm, P; Håkanson, R; Wang, ZY | 1 |
Baluk, P; Bowden, JJ; Bunnett, NW; McDonald, DM | 1 |
Baudoin, T; Ferencic, Z; Kalogjera, L; Pegan, B; Ries, M; Trotic, R | 1 |
Boucher, RC; Costa, DL; Lehmann, JR; McCarty, D; Pickles, RJ; Piedimonte, G | 1 |
Dimitriadou, V; Garbarg, M; Luffau, G; Miller, HR; Newlands, GJ; Rouleau, A; Schwartz, JC; Trung Tuong, MD | 1 |
Grundemar, L; Håkanson, R; Waldeck, K; Wang, ZY | 1 |
do Patrocínio, M; Lapa e Silva, JR; Leick-Maldonado, EA; Martins, MA; Paiva, SO; Sakae, RS; Saldiva, PH; Tibério, IF; Turco, GM; Warth, TN | 1 |
Canning, BJ | 1 |
Averbeck, B; Bickel, A; Luz, O; Schmelz, M | 1 |
Desouza, IA; Ribeiro-DaSilva, G | 1 |
Aubineau, P; Delépine, L | 1 |
Knotková-Urbancová, H; Kress, M; Reeh, PW; Vitásková, Z; Vlachová, V; Vyklický, L | 1 |
Didier, A; Igarashi, Y; Kaliner, MA; Kowalski, ML; Lundgren, JD | 1 |
Bullock, B; Dickerson, C; Undem, B; Winchurch, RA | 1 |
Elde, R; Schäffer, M; Stein, C; Zhang, Q | 1 |
De Freitas, GA; Santos, AR; Vedana, EM | 1 |
Dong, F; Hasegawa, S; Iijima, H; Nomura, A; Uchida, Y; Xiang, A; Zhang, MJ | 1 |
Helyes, Z; Németh, J; Oroszi, G; Pintér, E; Szolcsányi, J | 1 |
Hwang, SW; Jung, JY; Kwak, JY; Lee, WT; Oh, U | 1 |
Ansel, JC; Armstrong, CA; Bunnett, NW; Caughman, SW; Letran, EL; Naik, SM; Olerud, JE; Quinlan, KL; Song, IS | 1 |
Pierau, FK; Sann, H | 1 |
Hamilton, SG; McMahon, SB; Wade, A | 1 |
Abe, T; Arisaka, O; Oyama, M; Watanabe, M; Yoshihara, S | 1 |
Damas, J; Liégeois, JF | 1 |
Ebersberger, A; Messlinger, K; Oppmann, M; Pawlak, M; Schepelmann, K | 1 |
Dirig, DM; Yaksh, TL | 1 |
Chiang, YC; Hu, JW; Sessle, JB; Sunakawa, M | 1 |
Bergmann, R; Nicholas, RS; Winter, J; Woolf, CJ; Wren, P | 1 |
Cesare, P; McNaughton, PA; Moriondo, A; Vellani, V | 1 |
Abraham, J; Kobzik, L; Krishna Murthy, GG; Long, NC; Shore, SA; Weller, EA | 1 |
Lin, Q; Willis, WD; Wu, J | 1 |
Basbaum, AI; Caterina, MJ; Julius, D; Koltzenburg, M; Leffler, A; Malmberg, AB; Martin, WJ; Petersen-Zeitz, KR; Trafton, J | 1 |
Distler, C; Habelt, C; Kessler, F; Kress, M; Reeh, PW | 1 |
Atkinson, K; Bingham, S; Clapham, C; Davey, PT; Davis, JB; Grau, E; Gray, J; Gunthorpe, MJ; Harper, AJ; Harries, MH; Hatcher, JP; Hughes, SA; Latcham, J; Overend, P; Pugh, PL; Rance, K; Randall, A; Rogers, DC; Sheardown, SA | 1 |
Cho, H; Cho, S; Hwang, SW; Jung, J; Kang, CJ; Kim, D; Kwak, J; Lee, SY; Min, KH; Oh, U; Suh, YG | 1 |
Cascante, M; Creppy, EE; Ennamany, R; Richeux, F; Saboureau, D; Sanchez, D; Sanni, A | 1 |
Southall, MD; Vasko, MR | 1 |
Cervero, F; De Felipe, C; Hunt, SP; Laird, JM; Olivar, T; Roza, C | 1 |
Regoli, D | 1 |
Ito, T; Kawai, Y; Tamura, T; Yonehara, N; Yoshimura, M | 1 |
Helyes, Z; Németh, J; Pintér, E; Szilvássy, Z; Szolcsányi, J; Thán, M | 1 |
Adelson, DW; Kruger, L; Maidment, NT; Matsuka, Y; Neubert, JK; Spigelman, I | 1 |
Belmonte, C; Gallar, J; Pozo, MA; Rivera, L | 1 |
Janig, W; Levine, JD; Miao, FJ | 1 |
Choi, SY; Ha, H; Kim, KT | 1 |
Cirillo, R; Evangelista, S; Lippi, A; Maggi, CA; Manzini, S; Terracciano, R; Vieira, C | 1 |
Lacroix, JS; Malis, DD | 1 |
Blakeman, KH; Ernfors, P; Hao, JX; Hassani, H; Lucas, G; Naveilhan, P; Thorén, P; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
Bueno, L; Fioramonti, J; Garcia-Villar, R; Gay, J | 1 |
Itoh, M; Konemura, T; Kuraishi, Y; Sasaki, M; Sasamura, T; Tohda, C | 1 |
Fujimura, M; Kasahara, K; Liu, Q; Myou, S; Tachibana, H; Yasui, M | 1 |
Changeux, JP; Damaj, MI; Epping-Jordan, MP; Marubio, LM; Merlo-Pich, E; Salmon, AM | 1 |
Benowitz, NL; Levine, JD; Miao, FJ | 1 |
Bonaria Salis, M; Carta, L; Deiana, M; Emanueli, C; Franca Milia, A; Gaspa, L; Madeddu, P; Pinna, A; Stacca, T | 1 |
Gourine, AV; Kluger, MJ; Korsak, AS; Kozak, W; Kubatko, J; Rudolph, K; Tesfaigzi, J | 1 |
Gillard, SE; Hammond, DL; Hurley, RW; Miller, RJ; Oh, SB; Tran, PB | 1 |
Averbeck, B; Cirillo, R; Evangelista, S; Fetzer, S; Kress, M; Lippi, A; Maggi, CA; Manzini, S; Reeh, PW; Sauer, SK; Vieira, C | 1 |
Lin, Q; Willis, WD; Zou, X | 1 |
Kasai, M; Mizumura, K | 1 |
Amuzescu, B; Babes, A; Flonta, ML; Krause, U; Reid, G; Scholz, A | 1 |
Belmonte, C; Caprini, M; Carbonell, T; De Felipe, C; De La Pena, E; Ferrer-Montiel, A; García-Martinez, C; Gomis, A; Humet, M; Messeguer, A; Pérez-Paya, E; Planells-Cases, R; Sanchez-Baeza, F; Viana, F | 1 |
Chidiac, JJ; Hawwa, NN; Jabbur, SJ; Jurjus, AR; Massaad, CA; Rifai, K; Saadé, NE | 1 |
Carini, F; Catalioto, RM; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
Eysselein, VE; Gerken, G; Goebell, H; Hoffmann, P; Holtmann, G; Mazurkiewicz, J | 1 |
Chapman, V; Kelly, S | 1 |
Herbert, MK; Holzer, P | 1 |
Sluka, KA | 1 |
Kiernan, JA | 1 |
Fazekas, A; Györfi, A; Rosivall, L | 1 |
Green, PG; Levine, JD | 1 |
Dimaline, R; Dockray, GJ; Forster, ER; Louis, SM; Sandvik, AK | 1 |
Håkanson, R; Wallengren, J | 1 |
Hylden, JL; Noguchi, K; Ruda, MA | 1 |
Baluk, P; McDonald, DM; Nadel, JA | 1 |
Donnerer, J; Stein, C | 1 |
Garry, MG; Hargreaves, KM | 1 |
Helme, RD; Khalil, Z | 4 |
McDonald, DM | 1 |
Brain, SD; Buckley, TL; Jose, PJ; Williams, TJ | 1 |
Davis, W; Eysselein, VE; Nast, C; Patel, A; Reinshagen, M; Sternini, C | 1 |
Abelli, L; Del Bianco, E; Drapeau, G; Giachetti, A; Maggi, CA; Regoli, D; Rovero, P | 1 |
Cooper, AL; Rothwell, NJ | 1 |
Mantione, CR; Rodriguez, R | 1 |
McDonald, DM; Nadel, JA; Umeno, E | 2 |
Balu, A; De Sanctis, GT; Fick, G; Green, F; Lopez, A; Prior, M | 1 |
De, AK; Ghosh, JJ | 1 |
Glinska-Ferenz, M; Glinski, W; Pierozynska-Dubowska, M | 1 |
Abelli, L; Conte, B; Geppetti, P; Maggi, CA; Parlani, M; Somma, V | 1 |
Brodda-Jansen, G; Hedqvist, P; Lundeberg, T; Raud, J; Theodorsson, E | 1 |
Fujita, H; Kawabata, S; Kuraishi, Y; Matsumoto, T; Nakamura, A; Satoh, M | 1 |
Ferrell, WR; Lam, FY | 2 |
Bevan, S; Dray, A; Rang, HP | 1 |
Andersson, SE; Le Greves, P | 1 |
Buzzi, MG; Dimitriadou, V; Moskowitz, MA; Theoharides, TC | 1 |
Dickenson, A; Dray, A | 1 |
Chung, ES; Cuénoud, HF; Leeman, SE | 1 |
Gebhart, GF; Ness, TJ; Randich, A | 1 |
Otten, U; Vedder, H | 1 |
Lindsey, JR; McDonald, DM; Schoeb, TR | 1 |
Barthó, L; Herz, A; Stein, C | 1 |
Basbaum, AI; Coderre, TJ; Finkbeiner, WE; Levine, JD; White, DM | 1 |
Bohne, RL; Brand, LM; Fanelli, R; Lade, DA; Loomans, ME; Maddin, CS; Moorehead, DP; Reller, HH; Schwen, RJ; Skare, KL | 1 |
Didier, A; Jay, J; Kaliner, MA; Kowalski, ML | 1 |
Kumazawa, T | 1 |
Abelli, L; Furio, M; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Somma, V | 1 |
Foreman, JC | 2 |
Andrews, PV; Boyd, RL; Dandie, GW; Eglezos, A; Helme, RD | 1 |
Andrews, PV; Helme, RD; Khalil, Z; Thomas, KL | 1 |
Dockray, GJ; Jamieson, A; Louis, SM; Russell, NJ | 1 |
Imai, Y; Inoki, R; Shibutani, T; Yonehara, N | 1 |
Blumberg, PM; Szallasi, A | 1 |
Szolcsányi, J | 1 |
Andrews, PV; Eglezos, A; Helme, RD | 1 |
Markowitz, S; Moskowitz, MA; Saito, K | 2 |
Ahlstedt, S; Alving, K; Lundberg, JM; Ulfgren, AK | 1 |
LaHann, TR | 1 |
Andrews, PV; Helme, RD | 1 |
Helme, RD; McKernan, S | 1 |
28 review(s) available for capsaicin and Innate Inflammatory Response
Article | Year |
---|---|
5-Lipoxygenase as a drug target: A review on trends in inhibitors structural design, SAR and mechanism based approach.
Topics: Animals; Arachidonate 5-Lipoxygenase; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Molecular Structure; Structure-Activity Relationship | 2019 |
Capsaicin and TRPV1 Channels in the Cardiovascular System: The Role of Inflammation.
Topics: Animals; Blood Vessels; Capsaicin; Cardiovascular System; Humans; Inflammation; TRPV Cation Channels; Vasodilation | 2021 |
Capsaicin: A Potential Treatment to Improve Cerebrovascular Function and Cognition in Obesity and Ageing.
Topics: Aging; Animals; Capsaicin; Cognition; Dementia; Humans; Inflammation; Obesity; Quality of Life; TRPV Cation Channels | 2023 |
Capsaicin and Gut Microbiota in Health and Disease.
Topics: Animals; Antipruritics; Capsaicin; Gastrointestinal Microbiome; Humans; Inflammation | 2020 |
Capsaicin: Plants of the Genus Capsicum and Positive Effect of Oriental Spice on Skin Health.
Topics: Animals; Capsaicin; Capsicum; Humans; Inflammation; Skin; Spices; TRPV Cation Channels | 2020 |
Capsaicin: Friend or Foe in Skin Cancer and Other Related Malignancies?
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Capsicum; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models, Animal; Humans; Inflammation; Melanoma; Neoplasms; Skin Neoplasms | 2017 |
Transient receptor potential ion channels: powerful regulators of cell function.
Topics: Analgesics; Anti-Inflammatory Agents; Biomarkers; Calcium Channels; Capsaicin; Chronic Pain; Duloxetine Hydrochloride; Humans; Inflammation; Macrophages; Melanoma; Monocytes; Nerve Tissue Proteins; Pain, Postoperative; Respiratory Tract Diseases; Surgical Wound Infection; Thiophenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2014 |
Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Catechin; Colchicine; Curcumin; Humans; Imidazoles; Inflammation; Niacin; Resveratrol; Stilbenes | 2014 |
Capsaicin, Nociception and Pain.
Topics: Analgesics; Capsaicin; Humans; Inflammation; Nociception; Pain; Spinal Cord; TRPV Cation Channels | 2016 |
The Effect of Capsaicin on Salivary Gland Dysfunction.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Humans; Inflammation; Receptors, Muscarinic; Salivary Glands; Salivation; Sensory System Agents; TRPV Cation Channels | 2016 |
Inflammatory components of adipose tissue as target for treatment of metabolic syndrome.
Topics: Adipose Tissue; Animals; Capsaicin; Diet; Humans; Inflammation; Metabolic Syndrome; Mice; Obesity; Spices | 2009 |
TRPV1 as a cough sensor and its temperature-sensitive properties.
Topics: Animals; Body Temperature; Bronchoconstriction; Capsaicin; Cough; Dose-Response Relationship, Drug; Fever; Humans; Inflammation; Rats; Temperature; TRPV Cation Channels | 2011 |
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Biochemical pharmacology of the vanilloid receptor TRPV1. An update.
Topics: Animals; Capsaicin; Humans; Inflammation; Models, Molecular; Pain; Receptors, Drug | 2004 |
Regulation of inflammatory responses by sensory neurons: molecular mechanism(s) and possible therapeutic applications.
Topics: Calcitonin Gene-Related Peptide; Capsaicin; Endotoxins; Gastric Mucosa; Hot Temperature; Humans; Inflammation; Lung; Neurons, Afferent; Shock, Septic; TRPV Cation Channels; Vasodilator Agents | 2006 |
Neurogenic inflammation. A model for studying efferent actions of sensory nerves.
Topics: Afferent Pathways; Animals; Capillary Leak Syndrome; Capsaicin; Carotid Body; Efferent Pathways; Endothelium, Vascular; Guinea Pigs; Inflammation; Mycoplasma Infections; Neovascularization, Pathologic; Neurons, Afferent; Rats; Receptors, Neurokinin-1; Respiratory System; Respiratory Tract Diseases; Respiratory Tract Infections; Substance P; Venules | 1996 |
Potential role of tachykinins in inflammatory diseases.
Topics: Afferent Pathways; Anti-Inflammatory Agents; Capsaicin; Inflammation; Neuronal Plasticity; Receptors, Tachykinin; Sensory Receptor Cells; Tachykinins | 1997 |
Efferent functions of C-fiber nociceptors.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Efferent Pathways; Fibromyalgia; Humans; Inflammation; Nerve Fibers; Neurokinin A; Nociceptors; Skin; Substance P; Swine | 1998 |
Ion channels gated by heat.
Topics: Animals; Capsaicin; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ion Channel Gating; Ion Channels; Nociceptors; Pain | 1999 |
[Evaluation of various antagonists of CGRP, a neuromediator implicated in the inflammatory mechanisms of nasal mucosa].
Topics: Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Humans; Inflammation; Nasal Mucosa | 2000 |
[Neurogenic inflammation. I. Basic mechanisms, physiology and pharmacology].
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Inflammation; Nerve Fibers; Neuritis; Neurons, Afferent; Substance P | 2002 |
Neurogenic inflammation and the oral mucosa.
Topics: Capsaicin; Humans; Inflammation; Mouth Mucosa; Neurons, Afferent; Sensory Receptor Cells; Substance P; Vasodilation | 1992 |
Infections intensify neurogenic plasma extravasation in the airway mucosa.
Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Extravascular Lung Water; Guinea Pigs; Inflammation; Mucous Membrane; Neurons, Afferent; Rats; Respiratory System; Respiratory Tract Infections | 1992 |
Calcitonin gene-related peptide in inflammatory bowel disease and experimentally induced colitis.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis, Ulcerative; Colon; Denervation; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Neurons; Neurons, Afferent | 1992 |
Chemical activation of nociceptive peripheral neurones.
Topics: Bradykinin; Calcium-Transporting ATPases; Capsaicin; Humans; Inflammation; Ion Channels; Models, Neurological; Neurons; Nociceptors; Pain; Serotonin | 1991 |
Functions of the nociceptive primary neurons.
Topics: Afferent Pathways; Animals; Capsaicin; Humans; Inflammation; Mechanoreceptors; Neurons; Neuropeptides; Nociceptors; Reflex | 1990 |
Neuropeptides and the pathogenesis of allergy.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Hypersensitivity; Inflammation; Mast Cells; Neurokinin A; Neuropeptides; Peripheral Nerves; Substance P | 1987 |
Peptides and neurogenic inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Inflammation; Nervous System; Neuropeptides; Substance P | 1987 |
6 trial(s) available for capsaicin and Innate Inflammatory Response
Article | Year |
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Capsaicin and Its Effect on Exercise Performance, Fatigue and Inflammation after Exercise.
Topics: Athletic Performance; Bicycling; Capsaicin; Cross-Over Studies; Exercise; Exercise Test; Healthy Volunteers; Humans; Inflammation; Isometric Contraction; Male; Muscle Fatigue; Muscle, Skeletal; Performance-Enhancing Substances; Single-Blind Method; Young Adult | 2022 |
Effects of treatment with montelukast alone, budesonide/formoterol alone and a combination of both in cough variant asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Antitussive Agents; Asthma; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Capsaicin; Cough; Cyclopropanes; Formoterol Fumarate; Humans; Inflammation; Leukotriene Antagonists; Quinolines; Sulfides | 2022 |
PIEZO2 mediates injury-induced tactile pain in mice and humans.
Topics: Animals; Capsaicin; Chronic Disease; Disease Models, Animal; Humans; Hyperalgesia; Imaging, Three-Dimensional; Inflammation; Ion Channels; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neurons; Pain; Recombination, Genetic; Touch | 2018 |
Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Edema; Furans; Ginkgolides; Hindlimb; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Sensory System Agents; Vocalization, Animal | 2013 |
Topical Analgesic Nanolipid Vesicles Formulation of Capsaicinoids Extract of Bhut Jolokia (Capsicum chinense Jacq): Pharmacodynamic Evaluation in Rat Models and Acceptability studies in Human Volunteers.
Topics: Administration, Topical; Analgesics; Animals; Arthritis, Experimental; Capsaicin; Capsicum; Carrageenan; Drug Carriers; Formaldehyde; Freund's Adjuvant; Healthy Volunteers; Humans; In Vitro Techniques; Inflammation; Male; Nanoparticles; Phosphatidylcholines; Phytotherapy; Plant Extracts; Rats, Wistar; Skin; Skin Absorption | 2016 |
Oral capsaicin provides temporary relief for oral mucositis pain secondary to chemotherapy/radiation therapy.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents; Capsaicin; Female; Humans; Inflammation; Male; Middle Aged; Mouth Diseases; Neoplasms; Pain; Pilot Projects; Radiotherapy; Time Factors; Treatment Outcome | 1995 |
363 other study(ies) available for capsaicin and Innate Inflammatory Response
Article | Year |
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Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Animals; Capsaicin; Cells, Cultured; Drug Discovery; Female; Humans; Inflammation; Keratinocytes; Laurates; Mice; Mice, Inbred C57BL; Skin Diseases; TRPV Cation Channels | 2018 |
Inhibition of Spinal TRPV1 Reduces NMDA Receptor 2B Phosphorylation and Produces Anti-Nociceptive Effects in Mice with Inflammatory Pain.
Topics: Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Glutamic Acid; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred ICR; Pain; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Spinal Cord; TRPV Cation Channels | 2021 |
Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Freund's Adjuvant; Ganglia, Spinal; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Male; Mice; Monoterpenes; Neurons; Receptors, G-Protein-Coupled; Succinic Acid; TRPV Cation Channels | 2021 |
Lactobacillus rhamnosus attenuates Thai chili extracts induced gut inflammation and dysbiosis despite capsaicin bactericidal effect against the probiotics, a possible toxicity of high dose capsaicin.
Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Antipruritics; Capsaicin; Cytokines; Dysbiosis; Feces; Female; Gastrointestinal Tract; Humans; Inflammation; Lacticaseibacillus rhamnosus; Male; Mice; Mice, Inbred C57BL; Middle Aged; Plant Extracts; Probiotics; Tight Junctions; Young Adult | 2021 |
Antinociceptive and Anti-inflammatory Effect of Corynoline in Different Nociceptive and Inflammatory Experimental Models.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Berberine Alkaloids; Capsaicin; Carrageenan; Cytokines; Edema; Formaldehyde; Glutamates; Inflammation; Inflammation Mediators; Mice; Models, Theoretical; Nociception; Pain; Plant Extracts; Water | 2022 |
Inflammatory and contractile profile in LPS-challenged equine isolated bronchi: Evidence for IL-6 as a potential target against AHR in equine asthma.
Topics: Animals; Asthma; Bronchi; Capsaicin; Horses; Inflammation; Interleukin-33; Interleukin-6; Lipopolysaccharides; Neurokinin A; Transforming Growth Factor beta | 2022 |
Sensory testing and topical capsaicin can characterize patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Capsaicin; Humans; Inflammation; Middle Aged; Neuralgia; Sensory System Agents | 2022 |
Emodin Reduces Inflammatory and Nociceptive Responses in Different Pain-and Inflammation-Induced Mouse Models.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Emodin; Formaldehyde; Glutamates; Inflammation; Mice; Pain; Plant Extracts | 2023 |
Effects of Electroacupuncture on Gastrointestinal Motility Function, Pain, and Inflammation
Topics: Animals; Capsaicin; Electroacupuncture; Gastrointestinal Motility; Inflammation; NF-kappa B; Pain; Rats; Tumor Necrosis Factor-alpha | 2022 |
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
Topics: Capsaicin; Carrier Proteins; Cyclooxygenase 2; Humans; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Membrane Proteins; Sepsis; Thyroid Hormone-Binding Proteins; Thyroid Hormones; TRPV Cation Channels | 2022 |
Beneficial effects of capsaicin and dihydrocapsaicin on endothelial inflammation, nitric oxide production and antioxidant activity.
Topics: Antioxidants; Capsaicin; Capsicum; Endothelial Cells; Humans; Inflammation; Nitric Oxide; Tumor Necrosis Factor-alpha | 2022 |
Curcumin and capsaicin regulate apoptosis and alleviate intestinal inflammation induced by Clostridioides difficile in vitro.
Topics: Anti-Inflammatory Agents; Apoptosis; Bacterial Toxins; Capsaicin; Clostridioides; Clostridioides difficile; Clostridium Infections; Curcumin; Humans; Inflammation; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2022 |
Water Extract of
Topics: Animals; Capsaicin; Chrysanthemum; Fatty Acids, Volatile; Flowers; Gastrointestinal Microbiome; Inflammation; Lipopolysaccharides; Mice; Plant Extracts; Tumor Necrosis Factor-alpha | 2023 |
Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies.
Topics: Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Capsaicin; Curcumin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Docking Simulation; Spices | 2023 |
Improvement of wound healing by capsaicin through suppression of the inflammatory response and amelioration of the repair process.
Topics: Animals; Capsaicin; Cell Movement; Inflammation; Interleukin-6; Mice; Wound Healing | 2023 |
Molecular Links between Sensory Nerves, Inflammation, and Pain 2.0.
Topics: Afferent Pathways; Capsaicin; Humans; Inflammation; Neurons, Afferent; Pain; Peripheral Nervous System | 2023 |
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chronic Pain; Formaldehyde; Ganglia, Spinal; Hyperalgesia; Inflammation; Methoxsalen; Mice | 2023 |
Chronic pain models amplify transient receptor potential vanilloid 1 (TRPV1) receptor responses in adult rat spinal dorsal horn.
Topics: Animals; Capsaicin; Chronic Pain; Disease Models, Animal; Excitatory Postsynaptic Potentials; Freund's Adjuvant; Inflammation; Male; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Substantia Gelatinosa; Synaptic Transmission; TRPV Cation Channels | 2019 |
A systems biology approach to identify the key targets of curcumin and capsaicin that downregulate pro-inflammatory pathways in human monocytes.
Topics: Capsaicin; Cell Movement; Curcumin; Cytokines; Down-Regulation; Humans; Inflammation; Monocytes; Systems Biology; THP-1 Cells | 2019 |
Abnormal Pain Sensation in Mice Lacking the Prokineticin Receptor PKR2: Interaction of PKR2 with Transient Receptor Potential TRPV1 and TRPA1.
Topics: Amphibian Proteins; Animals; Capsaicin; Ganglia, Spinal; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Neuropeptides; Nociception; Pain; Plant Oils; Receptors, G-Protein-Coupled; TRPA1 Cation Channel; TRPV Cation Channels | 2020 |
Effects of gabapentinoids on responses of primary cultures from rat dorsal root ganglia to inflammatory or somatosensory stimuli.
Topics: Analgesics; Animals; Capsaicin; Female; Gabapentin; Ganglia, Spinal; Inflammation; Lipopolysaccharides; Male; Neuralgia; Neurons; Pregabalin; Primary Cell Culture; Rats; Rats, Wistar; Sensory System Agents; Somatosensory Cortex | 2020 |
Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation and mesolimbic pathway.
Topics: Animals; Appetite Regulation; Capsaicin; Coloring Agents; Energy Metabolism; Female; Furans; Gene Expression Regulation; Glucose Tolerance Test; Hypoglycemic Agents; Hypothalamus; Inflammation; Metformin; Mice; Mice, Inbred BALB C; Motor Activity; Olanzapine; Ruthenium Red; Sensory System Agents; TRPV Cation Channels | 2020 |
Capsaicin-Cyclodextrin Complex Enhances Mepivacaine Targeting and Improves Local Anesthesia in Inflamed Tissues.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anesthesia, Local; Anesthetics, Local; Animals; Calorimetry, Differential Scanning; Capsaicin; Carrageenan; Disease Models, Animal; Drug Compounding; Drug Stability; Drug Therapy, Combination; Excipients; Hyperalgesia; Inflammation; Magnetic Resonance Spectroscopy; Male; Mepivacaine; Mice; Microscopy, Electron, Scanning; Pain; Pain Management; Solubility; X-Ray Diffraction | 2020 |
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.
Topics: Adult; Animals; Capsaicin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enterobacteriaceae Infections; Female; Ganglia, Spinal; Histamine; Humans; Hypersensitivity; Inflammation; Irritable Bowel Syndrome; Male; Mice; Middle Aged; Neurons; Rats; Receptors, Cannabinoid; TRPV Cation Channels | 2021 |
Responses of spinal trigeminal neurons to noxious stimulation of paranasal cavities - a rat model of rhinosinusitis headache.
Topics: Animals; Bradykinin; Capsaicin; Dura Mater; Electric Stimulation; Headache; Inflammation; Male; Neurons; Neurons, Afferent; Paranasal Sinuses; Potassium Chloride; Rats; Trigeminal Nuclei; Trigeminal Nucleus, Spinal; Vasodilator Agents | 2021 |
Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capsaicin; Castor Oil; Colitis, Ulcerative; Colon; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Hyperalgesia; Inflammation; Lamiaceae; Male; Mice; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Visceral Pain | 2021 |
A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability.
Topics: Capsaicin; Drug Discovery; Ganglia, Spinal; Histamine; Humans; Inflammation; Laurates; Sensory Receptor Cells; TRPV Cation Channels | 2021 |
Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models.
Topics: Animals; Biomarkers; Capsaicin; Carrageenan; Endocannabinoids; Flurbiprofen; Gene Expression Regulation; Hyperalgesia; Inflammation; Lipopolysaccharides; Male; Mice; Pain | 2021 |
Pharmacological studies on aqueous extract of Launaea arborescens from southwest Algeria.
Topics: Algeria; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Behavior, Animal; Capsaicin; Edema; Formaldehyde; Histamine; Hot Temperature; Inflammation; Male; Medicine, Traditional; Mice, Inbred BALB C; Pain; Pain Measurement; Plant Extracts; Serotonin; Solutions; TRPV Cation Channels | 2021 |
Quinoa (Chenopodium quinoa Willd.) Seeds Increase Intestinal Protein Uptake.
Topics: Animals; Caco-2 Cells; Capsaicin; Chenopodium quinoa; Cholera Toxin; Dietary Proteins; Female; Goblet Cells; Humans; Inflammation; Intestines; Male; Permeability; Rats; Seeds | 2021 |
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity.
Topics: Acrylamide; Animals; Benzoquinones; Capsaicin; Inflammation; Male; Occludin; Oxidative Stress; Rats; Tight Junctions | 2022 |
Capsaicin affects macrophage anti-inflammatory activity via the MAPK and NF-κB signaling pathways.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Cytokines; Female; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Signal Transduction; Tumor Necrosis Factor-alpha | 2023 |
Inflammasome Signaling Regulates the Microbial-Neuroimmune Axis and Visceral Pain in Mice.
Topics: Animals; Anti-Bacterial Agents; Brain; Capsaicin; Caspase 1; Colon; Female; Gastrointestinal Microbiome; Inflammasomes; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroimmunomodulation; Signal Transduction; Visceral Pain | 2021 |
Preparation and Evaluation of PLGA-Coated Capsaicin Magnetic Nanoparticles.
Topics: Animals; Capsaicin; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Fluorescein; Fluorescent Dyes; HEK293 Cells; Humans; Inflammation; Lactic Acid; Magnetite Nanoparticles; Male; Mice, Inbred C57BL; Pain; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties | 2017 |
Gut Microbiota Mediates the Protective Effects of Dietary Capsaicin against Chronic Low-Grade Inflammation and Associated Obesity Induced by High-Fat Diet.
Topics: Animals; Anti-Obesity Agents; Capsaicin; Cluster Analysis; Diet, High-Fat; Disease Models, Animal; DNA, Bacterial; DNA, Ribosomal; Dysbiosis; Gastrointestinal Microbiome; Gastrointestinal Tract; Inflammation; Mice; Obesity; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA | 2017 |
TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Capsaicin; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Fibers, Unmyelinated; Neuronal Plasticity; Peripheral Nervous System Diseases; Posterior Horn Cells; Receptors, AMPA; Synaptic Transmission | 2017 |
Capsaicin reduces PLGA-induced fibrosis by promoting M2 macrophages and suppressing overall inflammatory Response.
Topics: Animals; Arginase; Biomarkers; Cadherins; Capsaicin; Cell Adhesion; Collagen; Cytokines; Fibrosis; Gene Expression Regulation, Enzymologic; Inflammation; Kinetics; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peritoneum; Polylactic Acid-Polyglycolic Acid Copolymer; Prostheses and Implants; RAW 264.7 Cells; Up-Regulation | 2018 |
Adult mouse sensory neurons on microelectrode arrays exhibit increased spontaneous and stimulus-evoked activity in the presence of interleukin-6.
Topics: Action Potentials; Animals; Bradykinin; Capsaicin; Cell Culture Techniques; Cells, Cultured; Dinoprostone; Electric Stimulation; Ganglia, Spinal; Hot Temperature; Inflammation; Inflammation Mediators; Interleukin-6; Male; Mice; Microelectrodes; Nociceptors; Sensory Receptor Cells | 2018 |
Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia.
Topics: Acetylcysteine; Action Potentials; Animals; Biotinylation; Capsaicin; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Erythromycin; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Neurons; Patch-Clamp Techniques; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Signal Transduction; TRPV Cation Channels | 2018 |
Activation of TRPV1 Prevents Salt-Induced Kidney Damage and Hypertension After Renal Ischemia-Reperfusion Injury in Rats.
Topics: Acute Kidney Injury; Animals; Capsaicin; Hypertension; Inflammation; Ischemic Preconditioning; Oxidative Stress; Protective Agents; Rats; Reperfusion Injury; Sodium Chloride, Dietary; TRPV Cation Channels | 2018 |
Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Capsaicin; Cells, Cultured; Disease Models, Animal; Female; Freund's Adjuvant; gamma-Aminobutyric Acid; Ganglia, Spinal; Hindlimb; Inflammation; Isoquinolines; Mice, Inbred C57BL; Motor Activity; Receptor, trkA; Sensory Receptor Cells; TRPV Cation Channels; Urea | 2018 |
Vti1b promotes TRPV1 sensitization during inflammatory pain.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Humans; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Qb-SNARE Proteins; RNA Interference; Sensory Receptor Cells; Signal Transduction; TRPV Cation Channels | 2019 |
Dual enkephalinase inhibitor PL265: a novel topical treatment to alleviate corneal pain and inflammation.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Benzalkonium Compounds; Capsaicin; Cornea; Corneal Injuries; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Pain; Pain Threshold; Propionates; Sensory System Agents; Trigeminal Ganglion | 2019 |
Diosmetin as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive activity in mice.
Topics: Analgesics; Animals; Calcium; Capsaicin; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Flavonoids; Inflammation; Male; Mice; Neuralgia; Pain; Pain Measurement; Spinal Cord; Synaptosomes; Toxicity Tests; TRPV Cation Channels | 2019 |
Enhancing analgesic and anti-inflammatory effects of capsaicin when loaded into olive oil nanoemulsion: An in vivo study.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chemistry, Pharmaceutical; Drug Carriers; Edema; Emulsions; Gels; Inflammation; Male; Nanoparticles; Olive Oil; Pain; Rabbits; Rats; Rats, Wistar; Skin Absorption | 2019 |
Inhibition of Muscular Nociceptive Afferents via the Activation of Cutaneous Nociceptors in a Rat Model of Inflammatory Muscle Pain.
Topics: Animals; Capsaicin; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Irritants; Mentha piperita; Models, Animal; Mustard Plant; Myalgia; Neurons, Afferent; Nociceptive Pain; Nociceptors; Physical Stimulation; Plant Oils; Rats; Rats, Sprague-Dawley; Skin | 2020 |
Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.
Topics: Animals; Behavior, Animal; Biopterins; Biosynthetic Pathways; Capsaicin; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Disease Models, Animal; Dystonic Disorders; Formaldehyde; Freund's Adjuvant; GTP Cyclohydrolase; Hot Temperature; Inflammation; Inheritance Patterns; Mice; Mice, Inbred C57BL; Motor Activity; Nociception; Pain; Phenylketonurias; Physical Stimulation; Rats; Stress, Mechanical | 2013 |
Capsaicin-sensitive vagal afferent neurons contribute to the detection of pathogenic bacterial colonization in the gut.
Topics: Animals; Campylobacter Infections; Capsaicin; Colony Count, Microbial; Gastrointestinal Tract; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Salmonella Infections; Vagus Nerve | 2013 |
Antiallodynic and analgesic effects of maslinic acid, a pentacyclic triterpenoid from Olea europaea.
Topics: Analgesics; Animals; Capsaicin; gamma-Aminobutyric Acid; Hyperalgesia; Inflammation; Mice; Molecular Structure; Olea; Pain; Pain Measurement; Pregabalin; Rotarod Performance Test; Time Factors; Triterpenes | 2013 |
Acute stress regulates nociception and inflammatory response induced by bee venom in rats: possible mechanisms.
Topics: Animals; Bee Venoms; Capsaicin; Disease Models, Animal; Edema; Hindlimb; Hyperalgesia; Inflammation; Male; Naloxone; Nociception; Oxidopamine; Pain; Rats; Rats, Sprague-Dawley; Restraint, Physical; Sciatic Nerve; Stress, Psychological; Sympathetic Nervous System | 2013 |
Vitexin inhibits inflammatory pain in mice by targeting TRPV1, oxidative stress, and cytokines.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Apigenin; Benzoquinones; Capsaicin; Carrageenan; Cytokines; Disease Models, Animal; Freund's Adjuvant; Glycosides; Hyperalgesia; Inflammation; Male; Mice; Molecular Structure; Oxidative Stress; Pain; Plant Extracts; TRPV Cation Channels | 2013 |
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
Topics: Acetone; Acrolein; Acrylamides; Acute Disease; Alkaloids; Analgesics; Animals; Aporphines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Pain; Cold Temperature; Freund's Adjuvant; Gene Expression; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2013 |
Activation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-α-induced inflammation in macrophages: role of liver X receptor α.
Topics: Animals; Atherosclerosis; Blotting, Western; Calcium; Capsaicin; Cells, Cultured; Chromatin Immunoprecipitation; Inflammation; Lipoproteins, LDL; Liver X Receptors; Macrophages; Mice; Orphan Nuclear Receptors; RNA, Small Interfering; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2013 |
Protective effect of fenspiride on the bronchi in rats with chronic obstructive pulmonary disease.
Topics: Animals; Bronchi; Bronchodilator Agents; Capsaicin; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Nerve Fibers, Unmyelinated; Nitrogen Dioxide; Procaine; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Wistar; Spiro Compounds; Tachykinins | 2013 |
Comparative anti-inflammatory properties of Capsaicin and ethyl-aAcetate extract of Capsicum frutescens linn [Solanaceae] in rats.
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Capsicum; Dose-Response Relationship, Drug; Inflammation; Phytotherapy; Plant Extracts; Plant Preparations; Random Allocation; Rats; Solanaceae | 2013 |
Trigeminal nerve stimulation triggers oral mast cell activation and vascular permeability.
Topics: Animals; Antipruritics; Capillary Permeability; Capsaicin; Evans Blue; Inflammation; Male; Mast Cells; Mouth; Rats; Rats, Sprague-Dawley; Substance P; Transcutaneous Electric Nerve Stimulation; Trigeminal Nerve | 2014 |
Polypeptide modulators of TRPV1 produce analgesia without hyperthermia.
Topics: Analgesia; Analgesics; Animals; Body Temperature; Capsaicin; Cell Line; Disease Models, Animal; Fever; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Male; Mice; Pain; Peptides; TRPV Cation Channels | 2013 |
Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Dextrans; Edema; Formaldehyde; Glutamic Acid; Histamine; Inflammation; Male; Mice; Naloxone; Pain; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Rats, Wistar; Sterculia | 2014 |
The chemerin receptor 23 agonist, chemerin, attenuates monosynaptic C-fibre input to lamina I neurokinin 1 receptor expressing rat spinal cord neurons in inflammatory pain.
Topics: Action Potentials; Adipokines; Animals; Capsaicin; Chemokines; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Freund's Adjuvant; In Vitro Techniques; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Nerve Fibers, Unmyelinated; Neurons; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Spinal Cord | 2014 |
Somatostatin 4 receptor activation modulates TRPV1[correction of TPRV1] currents in dorsal root ganglion neurons.
Topics: Animals; Butanes; Calcium; Capsaicin; Cells, Cultured; Freund's Adjuvant; Ganglia, Spinal; Inflammation; Male; Naphthalenes; Neurons; Nociception; Pain; Pertussis Toxin; Rats; Receptors, Somatostatin; Sulfones; TRPV Cation Channels | 2014 |
LASSBio-1135: a dual TRPV1 antagonist and anti-TNF-alpha compound orally effective in models of inflammatory and neuropathic pain.
Topics: Administration, Oral; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Enzyme Activation; Female; Hydrogen-Ion Concentration; Hyperalgesia; Imidazoles; Inflammation; Macrophages, Peritoneal; MAP Kinase Signaling System; Mice, Inbred BALB C; Neuralgia; Neutrophil Infiltration; Oocytes; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Time Factors; TRPV Cation Channels; Tumor Necrosis Factor-alpha; Xenopus laevis | 2014 |
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells.
Topics: Anilides; Animals; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; CD4-Positive T-Lymphocytes; Cells, Cultured; Cinnamates; Colitis; Humans; Inflammation; Interleukin-10; Intestines; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Antigen, T-Cell; Sensory System Agents; TRPV Cation Channels | 2014 |
Mass-spectrometric identification of T-kininogen I/thiostatin as an acute-phase inflammatory protein suppressed by curcumin and capsaicin.
Topics: Acute-Phase Proteins; Animals; Arachidonic Acid; Capsaicin; Curcumin; Diet; Disease Models, Animal; Glycoproteins; Inflammation; Kininogens; Male; Mass Spectrometry; Rats; Rats, Wistar; Reactive Oxygen Species | 2014 |
Sphingosine 1-phosphate to p38 signaling via S1P1 receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons.
Topics: Animals; Capsaicin; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Ions; Lysophospholipids; Male; Mice; Neurons, Afferent; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Proprotein Convertases; Sensory Receptor Cells; Serine Endopeptidases; Signal Transduction; Sphingosine | 2014 |
Inflammation-induced increase in nicotinic acetylcholine receptor current in cutaneous nociceptive DRG neurons from the adult rat.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Ganglia, Spinal; Hindlimb; Inflammation; Male; Membrane Potentials; Neuroanatomical Tract-Tracing Techniques; Nicotine; Nicotinic Agonists; Nociceptors; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, Nicotinic; Sensory System Agents; Skin | 2015 |
Inflammatory pain models with capsaicin or glutamate injections: are they comparable and reproducible?
Topics: Capsaicin; Glutamic Acid; Humans; Inflammation; Pain; Reproducibility of Results | 2014 |
Nanomiemgel--a novel drug delivery system for topical application--in vitro and in vivo evaluation.
Topics: Administration, Cutaneous; Aminoquinolines; Animals; Capsaicin; Cell Proliferation; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Drug Stability; Emulsions; Gels; Humans; Imiquimod; Immunohistochemistry; In Vitro Techniques; Inflammation; Keratinocytes; Micelles; Microdialysis; Microscopy, Atomic Force; Nanoparticles; Organ Size; Permeability; Psoriasis; Rats; Rheology; Skin Absorption; Spleen | 2014 |
The role of TRPV1 channels in carrageenan-induced mechanical hyperalgesia in mice.
Topics: Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Functional Laterality; Hyperalgesia; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Sensory System Agents; Touch; TRPV Cation Channels | 2015 |
Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.
Topics: Analgesics, Opioid; Calcium; Calcium Channels; Capsaicin; Electrophysiological Phenomena; HEK293 Cells; Humans; Inflammation; Isothiocyanates; Membrane Potentials; Nerve Tissue Proteins; Patch-Clamp Techniques; Receptors, Opioid, mu; Tramadol; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2015 |
A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis.
Topics: Activating Transcription Factor 3; Amidohydrolases; Anilides; Animals; Arachidonic Acids; Benzamides; Capsaicin; Carbamates; Cinnamates; Disease Models, Animal; Endocannabinoids; Ganglia, Spinal; Gene Expression; Hyperalgesia; Inflammation; Interleukin-6; Lumbar Vertebrae; Male; Osteoarthritis; Pain; Pain Management; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2015 |
[A novel role for the TRPV1 ion channel in CD4 T cell activation].
Topics: Animals; Calcium Signaling; Capsaicin; CD4 Antigens; CD4-Positive T-Lymphocytes; Humans; Inflammation; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphokines; Mice; Mice, Knockout; Protein Interaction Mapping; TRPV Cation Channels | 2015 |
Shp-1 dephosphorylates TRPV1 in dorsal root ganglion neurons and alleviates CFA-induced inflammatory pain in rats.
Topics: Animals; Calcium; Capsaicin; Cell Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Inflammation; Male; Membrane Potentials; Neurons; Pain; Pain Threshold; Patch-Clamp Techniques; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2015 |
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinogenesis; Cyclooxygenase 2; Female; Hyperplasia; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
HDAC4 is required for inflammation-associated thermal hypersensitivity.
Topics: Animals; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Down-Regulation; Freund's Adjuvant; Histone Deacetylases; Hyperalgesia; Hypersensitivity; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nociception; Pain; Protein Precursors; Sensory Receptor Cells; Transcription, Genetic; TRPV Cation Channels | 2015 |
Synovial TRPV1 is upregulated by 17-β-estradiol and involved in allodynia of inflamed temporomandibular joints in female rats.
Topics: Animals; Blotting, Western; Capsaicin; Cyclooxygenase 2; Estradiol; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Nerve Growth Factor; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Temporomandibular Joint; Temporomandibular Joint Disorders; Transcriptional Activation; TRPV Cation Channels; Up-Regulation | 2015 |
Therapeutic effects of naringin in a guinea pig model of ovalbumin-induced cough-variant asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cough; Disease Models, Animal; Flavanones; Guinea Pigs; Inflammation; Male; Ovalbumin | 2015 |
Selective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alata.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Capsaicin; Coumarins; Ganglia, Spinal; HEK293 Cells; Humans; Inflammation; Ion Channel Gating; Magnetic Resonance Spectroscopy; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Murraya; Neurons; Nociceptors; Pain; Rats; TRPV Cation Channels | 2016 |
TRPV1 channel modulation by hyaluronan reduces pain.
Topics: Action Potentials; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Extracellular Matrix; HEK293 Cells; Hot Temperature; Humans; Hyaluronic Acid; Inflammation; Injections, Intra-Articular; Ion Channel Gating; Knee Joint; Neuralgia; TRPV Cation Channels | 2016 |
Nonparalytic botulinum molecules for the control of pain.
Topics: Animals; Botulinum Toxins, Type A; Capsaicin; Cell Count; Cell Proliferation; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Keratinocytes; Male; Motor Activity; Nerve Fibers, Unmyelinated; Neuralgia; Neuromuscular Agents; Pain Measurement; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn | 2016 |
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase.
Topics: Acrylamides; Amidohydrolases; Analgesia; Animals; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Carrageenan; Disease Models, Animal; Ethanolamines; Formaldehyde; Genotype; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Ligands; Lumbar Vertebrae; Mice, Inbred C57BL; Mice, Knockout; Nociception; Pain; Pain Threshold; Phenotype; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Receptor, Cannabinoid, CB1; Skin; Spinal Cord Dorsal Horn; TRPV Cation Channels | 2016 |
Dihydrocapsaicin suppresses proinflammatory cytokines expression by enhancing nuclear factor IA in a NF-κB-dependent manner.
Topics: Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Capsaicin; Cytokines; Gene Expression Profiling; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; NF-kappa B; NFI Transcription Factors; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2016 |
Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain.
Topics: Acetanilides; Analgesics; Animals; Anti-Inflammatory Agents; Calcium Signaling; Capsaicin; HEK293 Cells; Humans; Inflammation; Mice; Mice, Knockout; Mustard Plant; Oximes; Pain; Plant Oils; Purines; TRPA1 Cation Channel | 2016 |
Genotype-dependent responsivity to inflammatory pain: A role for TRPV1 in the periaqueductal grey.
Topics: Animals; Anxiety; Behavior, Animal; Capsaicin; Depression; Diterpenes; Genotype; Inflammation; Male; Pain; Periaqueductal Gray; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; RNA, Messenger; TRPV Cation Channels | 2016 |
The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel.
Topics: Alkaloids; Animals; Anthelmintics; Antibiotics, Antineoplastic; Capsaicin; Cells, Cultured; Cesium; Chlorides; Enzyme Inhibitors; Freund's Adjuvant; Ganglia, Spinal; Gene Expression; Guanidines; HEK293 Cells; HSC70 Heat-Shock Proteins; Humans; Inflammation; Matrines; Mice; Neurons; Pain; Potassium Channel Blockers; Quinolizines; Rats; TRPV Cation Channels | 2016 |
Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain.
Topics: Animals; Capsaicin; Cell-Penetrating Peptides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Inflammation; Lipopeptides; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Pain Threshold; Piperidines; Protein Kinase C; Rats; Rats, Long-Evans; Sex Characteristics; Spinal Cord | 2016 |
SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons.
Topics: Animals; Behavior, Animal; Blotting, Western; Capsaicin; Ganglia, Spinal; Humans; Hyperalgesia; Immunohistochemistry; Inflammation; Mice; Mice, Knockout; Microfilament Proteins; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neuralgia; Pain; Patch-Clamp Techniques; Presynaptic Terminals; Reverse Transcriptase Polymerase Chain Reaction; Sensory Receptor Cells; Sensory System Agents; Spinal Cord; TRPV Cation Channels | 2016 |
High-concentration topical capsaicin may abolish the clinical manifestations of allergic contact dermatitis by effects on induction and elicitation.
Topics: Administration, Cutaneous; Allergens; Capsaicin; Cytokines; Dermatitis, Allergic Contact; Humans; Inflammation; Lymph Nodes; Models, Theoretical; Neuropeptides; Skin | 2017 |
Catecholamines reduce transient receptor potential vanilloid type 1 desensitization in cultured dorsal root ganglia neurons.
Topics: Adrenergic Antagonists; Animals; Calcium; Capsaicin; Catecholamines; Cells, Cultured; Epinephrine; Ganglia, Spinal; Inflammation; Male; Neurons; Norepinephrine; Pain; Rats; Rats, Wistar; Receptors, Adrenergic; Skin; TRPV Cation Channels | 2016 |
Capsaicin pretreatment reversed pulmonary arterial hypertension by alleviating inflammation via p38MAPK pathway.
Topics: Animals; Capsaicin; Hypertension, Pulmonary; Inflammation; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Premedication; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2017 |
Behavioral and electrophysiological evidence for the differential functions of TRPV1 at early and late stages of chronic inflammatory nociception in rats.
Topics: Animals; Capsaicin; Chronic Disease; Electric Stimulation; Evoked Potentials; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Injections, Spinal; Male; Pain; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; TRPV Cation Channels | 2008 |
G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia.
Topics: Analysis of Variance; Animals; Blotting, Western; Capsaicin; Cell Line; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; G-Protein-Coupled Receptor Kinases; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Pain Threshold; Peroxidase; Proto-Oncogene Proteins c-fos; Visceral Afferents | 2009 |
Ultraviolet-B induced inflammation of human skin: characterisation and comparison with traditional models of hyperalgesia.
Topics: Adult; Burns; Capsaicin; Female; Hot Temperature; Humans; Hyperalgesia; Inflammation; Male; Models, Neurological; Nociceptors; Pain Threshold; Radiation Dosage; Sensory Receptor Cells; Sensory System Agents; Skin; Sunburn; Time Factors; Ultraviolet Rays; Young Adult | 2009 |
Increases in transient receptor potential vanilloid-1 mRNA and protein in primary afferent neurons stimulated by protein kinase C and their possible role in neurogenic inflammation.
Topics: Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Fluorescent Antibody Technique; Ganglia, Spinal; Gene Expression; Immunohistochemistry; Inflammation; Male; Microscopy, Confocal; Neurons, Afferent; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensory System Agents; TRPV Cation Channels; Up-Regulation | 2009 |
TNBS-induced inflammation modulates the function of one class of low-threshold rectal mechanoreceptors in the guinea pig.
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Inflammation; Inflammation Mediators; Male; Mechanoreceptors; Muscle Contraction; Rectum; Trinitrobenzenesulfonic Acid | 2008 |
Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1.
Topics: Administration, Oral; Animals; Benzothiazoles; Capsaicin; Cell Line; Chemistry, Pharmaceutical; Drug Design; Guinea Pigs; Humans; Inflammation; Inhibitory Concentration 50; Models, Chemical; Niacinamide; Rats; TRPV Cation Channels | 2008 |
Change of AMPA receptors in spinal nociceptive synapses during inflammatory hyperalgesia.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Humans; Hyperalgesia; Inflammation; Long-Term Potentiation; Nociceptors; Receptors, AMPA; Sensory System Agents; Spinal Cord; Synapses; Synaptic Transmission | 2008 |
Acid increases inflammatory pain in rats: effect of local peripheral ASICs inhibitors.
Topics: Acid Sensing Ion Channels; Amiloride; Analgesics; Animals; Capsaicin; Female; Formaldehyde; Hydrogen-Ion Concentration; Inflammation; Nerve Tissue Proteins; Pain; Rats; Rats, Wistar; Serotonin; Sodium Channels | 2009 |
Tumor bearing decreases systemic acute inflammation in rats--role of mast cell degranulation.
Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Carrageenan; Cell Degranulation; Dextrans; Edema; Histamine; Inflammation; Mast Cells; Neoplasm Transplantation; Neoplasms; Neutrophil Activation; Neutrophil Infiltration; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Substance P | 2009 |
Prophylactic proopiomelanocortin expression alleviates capsaicin-induced neurogenic inflammation in rat trachea.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Cell Line; Cell Movement; Gene Expression Regulation; Humans; Inflammation; Male; Melanocortins; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Time Factors; Trachea | 2009 |
Interleukin-1alpha regulates substance P expression and release in adult sensory neurons.
Topics: Age Factors; Animals; Capsaicin; Cells, Cultured; Female; Ganglia, Spinal; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Nerve Growth Factor; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Substance P; Up-Regulation | 2009 |
Antinociceptive and anti-allodynic effects of 3-alkynyl selenophene on different models of nociception in mice.
Topics: Analgesics; Animals; Bradykinin; Capsaicin; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Hot Temperature; Hyperalgesia; Immersion; Inflammation; Male; Mice; Motor Activity; Organoselenium Compounds; Pain Measurement; Reaction Time; Tetradecanoylphorbol Acetate | 2009 |
Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.
Topics: Adiponectin; Adipose Tissue; Animals; Anti-Inflammatory Agents; Blood Glucose; Capsaicin; Dietary Fats; Dietary Supplements; Disease Models, Animal; Fatty Liver; Flow Cytometry; Gene Expression; Glucose Intolerance; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Leptin; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; PPAR alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides; TRPV Cation Channels | 2010 |
Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons.
Topics: Action Potentials; Animals; Aquaporin 1; Bradykinin; Capsaicin; Cell Line, Tumor; Dinoprostone; Ganglia, Spinal; Gene Expression Regulation; Inflammation; Mice; Mice, Knockout; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Oxytocics; Pain; Pain Management; Perception; Sensory System Agents; Sodium Channels; Vasodilator Agents | 2010 |
The effects of sympathetic outflow on upregulation of vanilloid receptors TRPV(1) in primary afferent neurons evoked by intradermal capsaicin.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Drug Administration Routes; Functional Laterality; Ganglia, Spinal; Inflammation; Male; Metacarpus; Neurons, Afferent; Protein Kinase C; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sensory System Agents; Sympathectomy; TRPV Cation Channels; Up-Regulation | 2010 |
Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signaling.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Capsaicin; Cell Line; Cell Survival; Dermatitis; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Immunohistochemistry; Inflammation; Keratinocytes; Mice; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; src-Family Kinases; Ultraviolet Rays | 2010 |
The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice.
Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Benzamides; Capsaicin; Carbamates; Carrageenan; Hyperalgesia; Inflammation; Mice; Receptor, Cannabinoid, CB1; Serotonin; TRPV Cation Channels | 2010 |
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
Topics: Analgesics; Animals; Biological Availability; Capsaicin; Chlorocebus aethiops; COS Cells; Hot Temperature; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Microsomes, Liver; Naphthyridines; Pain; Pyrazines; Pyridines; Pyrimidines; Quinazolines; Quinolines; Rats; Structure-Activity Relationship; TRPV Cation Channels | 2010 |
Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in the spinal cord dorsal horn of rats with neuropathic and inflammatory pain.
Topics: Animals; Capsaicin; Glutamic Acid; Inflammation; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Posterior Horn Cells; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate | 2010 |
Cholecystokinin/Cholecystokinin-1 receptor-mediated peripheral activation of the afferent vagus by enteral nutrients attenuates inflammation in rats.
Topics: Animals; Bacterial Translocation; Capsaicin; Cholecystokinin; Enteral Nutrition; Inflammation; Intestinal Absorption; Lipids; Male; Neural Pathways; Peptide Fragments; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Shock, Hemorrhagic; Vagus Nerve | 2010 |
Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid-containing immune cells to inhibit inflammatory pain.
Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Endorphins; Endothelium, Vascular; Flow Cytometry; Freund's Adjuvant; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Male; Nerve Fibers; Oxidopamine; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Sensory Receptor Cells; Sympathetic Nervous System; Sympatholytics; Tyrosine 3-Monooxygenase | 2010 |
NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing loss.
Topics: Animals; Capsaicin; Cells, Cultured; Cochlea; Evoked Potentials; Hearing Loss; Immunohistochemistry; Inflammation; Male; Mice; Microscopy, Electron, Scanning; NADPH Oxidases; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; STAT1 Transcription Factor; TRPV Cation Channels | 2011 |
Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bupivacaine; Capsaicin; Ganglia, Spinal; Indomethacin; Inflammation; Male; Morphine; Neurons; Pain; Pain Measurement; Patch-Clamp Techniques; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Sodium Channel Blockers | 2010 |
Cutaneous limb inflammation produces analgesia to pressure pain in the ipsilateral forehead of healthy volunteers.
Topics: Adolescent; Adult; Analgesia; Capsaicin; Complex Regional Pain Syndromes; Female; Forearm; Forehead; Functional Laterality; Humans; Hyperalgesia; Inflammation; Irritants; Pain; Pain Perception; Pain Threshold; Pressure; Skin; Young Adult | 2011 |
C-fibers, but not the transient potential receptor vanilloid 1 (TRPV1), play a role in experimental allergic airway inflammation.
Topics: Allergens; Anilides; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cinnamates; Cytokines; Female; Gene Expression Regulation; Hypersensitivity; Immunization; Inflammation; Leukocytes; Lung; Mice; Mice, Inbred BALB C; Nerve Fibers, Unmyelinated; NF-kappa B; Ovalbumin; P-Selectin; Respiratory System; TRPV Cation Channels | 2011 |
TRPM3 is a nociceptor channel involved in the detection of noxious heat.
Topics: Acrylamides; Animals; Behavior, Animal; Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Capsaicin; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Hot Temperature; Humans; Hyperalgesia; Inflammation; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Nifedipine; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Plant Oils; Pregnenolone; Sensory Receptor Cells; Telemetry; Time Factors; Transfection; Transient Receptor Potential Channels; Trigeminal Ganglion; TRPA1 Cation Channel; TRPM Cation Channels | 2011 |
17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Cell Line; Docosahexaenoic Acids; Freund's Adjuvant; Ganglia, Spinal; HEK293 Cells; Hot Temperature; Humans; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Pain; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; TRPV Cation Channels | 2012 |
Capsaicin induces reflex scratching in inflamed skin.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Capsaicin; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Freund's Adjuvant; Inflammation; Injections, Intradermal; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Pain; Pruritus; Receptors, Opioid, mu; Reflex; Sensory System Agents; Skin; Time Factors; TRPV Cation Channels | 2011 |
Spinal glycinergic and GABAergic neurons expressing C-fos after capsaicin stimulation are increased in rats with contralateral neuropathic pain.
Topics: Animals; Capsaicin; Freund's Adjuvant; Functional Laterality; GABAergic Neurons; Glycine; Inflammation; Male; Molecular Imaging; Neuralgia; Neurons; Pain; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord | 2011 |
Persistent epithelial barrier alterations in a rat model of postinfectious gut dysfunction.
Topics: Animals; Capsaicin; Chymases; Enteric Nervous System; Gastrointestinal Tract; Inflammation; Intestinal Mucosa; Ion Transport; Male; Mast Cells; Mastocytosis; Neurotransmitter Agents; Permeability; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Substance P; Tetrodotoxin; Trichinella spiralis; Trichinellosis | 2011 |
Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling.
Topics: Animals; Capsaicin; Cell Nucleus; Chemokines; Cytokines; Extracellular Signal-Regulated MAP Kinases; Hydrogen Sulfide; Inflammation; Male; Mice; NF-kappa B; Phosphorylation; Sepsis; Substance P; TRPV Cation Channels | 2011 |
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury.
Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Death; Cell Line; Cell Line, Transformed; Cells, Cultured; Endoplasmic Reticulum Stress; Humans; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Alveoli; Pulmonary Edema; Transcription Factor CHOP; TRPV Cation Channels | 2012 |
Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation.
Topics: Animals; Axons; Capsaicin; Cells, Cultured; Immunoblotting; Inflammation; Male; Mice; Mice, Knockout; Neuregulin-1; Pain; Patch-Clamp Techniques; Sensation; Sensory Receptor Cells; Sensory System Agents; Signal Transduction; Thermosensing; TRPV Cation Channels | 2011 |
Metabotropic glutamate antagonists alone and in combination with morphine: comparison across two models of acute pain and a model of persistent, inflammatory pain.
Topics: Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Inflammation; Male; Morphine; Narcotics; Pain; Pain Measurement; Pyridines; Quinolines; Rats; Rats, Inbred F344; Receptors, Metabotropic Glutamate | 2011 |
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde; Glycyrrhetinic Acid; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ligation; Male; Neuralgia; Neurokinin A; Neurokinin B; Pain; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Sciatic Nerve; Substance P | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats.
Topics: Analgesics, Non-Narcotic; Animals; Bradykinin; Capsaicin; Carrageenan; Chalcone; Cyclooxygenase 2; Drugs, Chinese Herbal; Ganglia, Spinal; Inflammation; Male; Pain; Plant Extracts; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve; Substance P; Tachykinins | 2012 |
Transient receptor potential vanilloid 1 - a polymodal nociceptive receptor - plays a crucial role in formaldehyde-induced skin inflammation in mice.
Topics: Animals; Capsaicin; Disease Models, Animal; Drug Eruptions; Female; Formaldehyde; Inflammation; Mice; Mice, Inbred BALB C; Mice, Knockout; Nerve Growth Factors; RNA, Messenger; Time Factors; TRPV Cation Channels | 2012 |
New models of experimental parotitis and parotid gland distension in rats.
Topics: Animals; Capsaicin; Catheterization; Disease Models, Animal; Freund's Adjuvant; Inflammation; Neurons; Pain Measurement; Parotid Gland; Parotitis; Physical Stimulation; Rats | 2012 |
Increased central and peripheral inflammation and inflammatory hyperalgesia in Zucker rat model of leptin receptor deficiency and genetic obesity.
Topics: Adiponectin; Animals; Capsaicin; Carrageenan; Down-Regulation; Edema; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Morphine; Nitric Oxide Synthase Type II; Nociception; Obesity; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Zucker; Receptors, Leptin; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature.
Topics: Analgesics; Animals; Body Temperature; Bronchoconstriction; Capsaicin; Edema; Female; Hyperalgesia; Hypothermia; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Respiratory System; Sciatic Nerve; TRPV Cation Channels | 2012 |
Role of C-fibers during acute and chronic stress on formalin-induced paw edema in rats.
Topics: Animals; Capsaicin; Dexamethasone; Edema; Formaldehyde; Inflammation; Male; Nerve Fibers, Unmyelinated; Rats; Rats, Wistar; Stress, Physiological; Swimming | 2012 |
Mechanisms underlying ectopic persistent tooth-pulp pain following pulpal inflammation.
Topics: Animals; Capsaicin; Carbocyanines; Citrates; Dental Pulp; Extracellular Signal-Regulated MAP Kinases; Freund's Adjuvant; Glial Fibrillary Acidic Protein; Inflammation; Male; Masseter Muscle; Models, Biological; Molar; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Satellite Cells, Skeletal Muscle; Stilbamidines; Toothache; Trigeminal Ganglion; TRPV Cation Channels | 2013 |
A unique representation of heat allodynia in the human brain.
Topics: Adult; Afferent Pathways; Brain; Brain Mapping; Capsaicin; Cerebrovascular Circulation; Functional Laterality; Humans; Hyperalgesia; Inflammation; Male; Nerve Fibers; Nerve Fibers, Myelinated; Nociceptors; Pain Measurement; Pain Threshold; Skin; Tomography, Emission-Computed | 2002 |
Upregulation of neurokinin-1 receptor expression in rat spinal cord by an N-terminal metabolite of substance P.
Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Ganglia, Spinal; Immunohistochemistry; Inflammation; Isomerism; Male; Pain; Peptide Fragments; Posterior Horn Cells; Presynaptic Terminals; Protein Precursors; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tachykinins; Up-Regulation | 2002 |
Augmentation of allergic early-phase reaction by nerve growth factor.
Topics: Acute-Phase Reaction; Allergens; Animals; Asthma; Capsaicin; Data Interpretation, Statistical; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypersensitivity; Immunoglobulin E; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nerve Growth Factor; Neuronal Plasticity; Promoter Regions, Genetic; Serotonin | 2002 |
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.
Topics: Algorithms; Animals; Anticonvulsants; Capsaicin; Carbamazepine; Dose-Response Relationship, Drug; Guinea Pigs; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptors, Drug; Sciatic Nerve | 2003 |
Pharmacology of vagal afferent nerve activity in guinea pig airways.
Topics: Animals; Capsaicin; Electrophysiology; Guinea Pigs; Inflammation; Lung; Neurons, Afferent; Organ Culture Techniques; Phenotype; Vagus Nerve | 2003 |
Bone marrow transplantation reveals an essential synergy between neuronal and hemopoietic cell neurokinin production in pulmonary inflammation.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Capsaicin; Enzyme-Linked Immunosorbent Assay; Gene Deletion; Gene Expression Regulation; Hematopoietic Stem Cells; Immune System; Inflammation; Ligands; Lung; Mice; Mice, Transgenic; Neurokinin A; Neurons; Protein Precursors; Respiration; Substance P; Tachykinins; Time Factors; Trachea | 2003 |
State-dependent phosphorylation of epsilon-isozyme of protein kinase C in adult rat dorsal root ganglia after inflammation and nerve injury.
Topics: Animals; Behavior, Animal; Capsaicin; Carrageenan; Disease Models, Animal; Diterpenes; Freund's Adjuvant; Ganglia, Spinal; Hindlimb; Hyperalgesia; Inflammation; Ligation; Male; Neurons; Nociceptors; Pain; Pain Measurement; Peripheral Nervous System Diseases; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Drug | 2003 |
N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflammatory and neuropath
Topics: Analgesics; Animals; Ataxia; Capsaicin; Hyperalgesia; Inflammation; Male; Nerve Tissue; Pain; Pain Threshold; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Drug | 2003 |
Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors.
Topics: Administration, Inhalation; Animals; Apoptosis; Capsaicin; Cell Death; Cell Line; Cloning, Molecular; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Flow Cytometry; Humans; Indicators and Reagents; Inflammation; Interleukin-6; Lung; Male; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
SYM 2081, an agonist that desensitizes kainate receptors, attenuates capsaicin and inflammatory hyperalgesia.
Topics: Animals; Capsaicin; Carrageenan; Dose-Response Relationship, Drug; Drug Administration Routes; Glutamates; Hyperalgesia; Inflammation; Lower Extremity; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Kainic Acid | 2003 |
Intradermal capsaicin inhibits lumbar dorsal horn neuronal responses to colorectal distention.
Topics: Action Potentials; Animals; Capsaicin; Colon; Inflammation; Injections, Intradermal; Lumbar Vertebrae; Male; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Rectum | 2003 |
A study of the cough reflex in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents; Bradykinin; Brain-Derived Neurotrophic Factor; Bronchial Provocation Tests; Capsaicin; Case-Control Studies; Cough; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Nerve Growth Factor; Neutrophils; Prednisolone; Pulmonary Fibrosis; Sputum; Substance P; Total Lung Capacity; Treatment Outcome | 2003 |
Stimulation of spinal 5-HT(2A/2C) receptors potentiates the capsaicin-induced in vivo release of substance P-like immunoreactivity in the rat dorsal horn.
Topics: Animals; Capsaicin; Carrageenan; Inflammation; Male; Microdialysis; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists; Spinal Cord; Substance P | 2003 |
Protein kinases regulate the phosphorylation of the GluR1 subunit of AMPA receptors of spinal cord in rats following noxious stimulation.
Topics: Amino Acid Sequence; Animals; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Inflammation; Male; Nociceptors; Pain; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine | 2003 |
Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Enteric Nervous System; Inflammation; Mice; Neurons, Afferent; Neuropeptides; Oligopeptides; Piperidines; Quinuclidines; Receptor, PAR-2; Receptors, Neurokinin-1 | 2003 |
Regulation of peripheral inflammation by spinal adenosine: role of somatic afferent fibers.
Topics: Adenosine; Animals; Capsaicin; Feedback; Inflammation; Injections, Spinal; Male; Nerve Fibers; Neurons, Afferent; Neuropeptides; Neutrophil Infiltration; Neutrophils; Oxidopamine; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Nerve Roots; Sympathectomy, Chemical; Sympatholytics | 2003 |
Mechanosensitive duodenal afferents contribute to vagal modulation of inflammation in the rat.
Topics: Animals; Bradykinin; Capsaicin; Catheterization; Duodenum; Electric Stimulation; Fasting; Inflammation; Knee Joint; Male; Mechanoreceptors; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Vagotomy; Vagus Nerve | 2004 |
Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin.
Topics: Animals; Arginine; Benzazepines; Bicuculline; Capsaicin; Foot; GABA Antagonists; Inflammation; Injections, Spinal; Laser-Doppler Flowmetry; Male; Pain; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Skin; Spinal Cord; Sympathectomy; Sympathetic Nervous System | 2004 |
Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Ear; Edema; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Neurokinin-1 Receptor Antagonists; Piperidines; Plant Extracts; Plant Oils; Quinuclidines; Receptors, Drug; Receptors, Neurokinin-1; Staining and Labeling; Time Factors; TRPV Cation Channels | 2004 |
The analgesic effect induced by capsaicin is enhanced in inflammatory states.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Disease Models, Animal; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Receptors, Drug; Time Factors | 2004 |
Implantation of tumoral XC cells induces chronic, endothelin-dependent, thermal hyperalgesia in mice.
Topics: Animals; Avian Sarcoma Viruses; Capsaicin; Cell Line, Transformed; Cell Line, Tumor; Chronic Disease; Endothelin Receptor Antagonists; Endothelins; Fibroblasts; Genetic Vectors; Hindlimb; Hyperalgesia; Inflammation; Male; Mice; Morphine; Neoplasm Regression, Spontaneous; Neoplasm Transplantation; Nociceptors; Oligopeptides; Pain Measurement; Peptides, Cyclic; Piperidines; Rats; Reaction Time; Receptors, Endothelin | 2004 |
The effect of cutaneous mast cell degranulation on sensitivity to heat.
Topics: Adolescent; Adult; Axons; Capsaicin; Hot Temperature; Humans; Inflammation; Iontophoresis; Leukocytes; Male; Mast Cells; Norepinephrine; p-Methoxy-N-methylphenethylamine; Pain; Sensitivity and Specificity; Skin; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Pro-nociceptive role of peripheral galanin in inflammatory pain.
Topics: Action Potentials; Animals; Axons; Behavior, Animal; Capsaicin; Cell Count; Dose-Response Relationship, Drug; Drug Interactions; Galanin; Immunohistochemistry; In Vitro Techniques; Inflammation; Male; Microscopy, Electron; Pain; Pain Measurement; Peptide Fragments; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Receptor, Galanin, Type 2; Receptors, Drug; Skin; Substance P | 2004 |
Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.
Topics: Administration, Oral; Animals; Camphanes; Cannabidiol; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hyperalgesia; Inflammation; Italy; Male; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Drug; Rimonabant; Time Factors | 2004 |
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.
Topics: Androstadienes; Animals; Capsaicin; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Inflammation; Ion Channels; Male; Morpholines; Nerve Growth Factor; Neurons, Afferent; Pain Measurement; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Skin; TRPV Cation Channels; Wortmannin | 2004 |
Regulation mechanisms of vanilloid receptors.
Topics: Adenosine Triphosphate; Animals; Capsaicin; Hot Temperature; Humans; Inflammation; Mice; Models, Neurological; Neurons, Afferent; Nociceptors; Pain; Rats; Receptors, Drug; Receptors, Purinergic P2 | 2004 |
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
Small-dose capsaicin reduces systemic inflammatory responses in septic rats.
Topics: Animals; Antioxidants; Calcitonin Gene-Related Peptide; Capsaicin; Cecum; Female; Inflammation; Interleukin-10; Interleukin-6; Ligation; Lysosomes; Macrophages; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Superoxide Dismutase; Tissue Distribution; Tumor Necrosis Factor-alpha | 2004 |
Estrogen and inflammation increase the excitability of rat temporomandibular joint afferent neurons.
Topics: Action Potentials; Analysis of Variance; Animals; Capsaicin; Carbocyanines; Cell Count; Cell Size; Cells, Cultured; Chi-Square Distribution; Electric Capacitance; Electric Stimulation; Estrogens; Female; Freund's Adjuvant; Glycoproteins; Immunohistochemistry; Inflammation; Lectins; Membrane Potentials; Neurofilament Proteins; Neurons, Afferent; Ovariectomy; Patch-Clamp Techniques; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Temporomandibular Joint; Trigeminal Ganglion; Versicans | 2005 |
Neurokinins and inflammatory cell iNOS expression in guinea pigs with chronic allergic airway inflammation.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Bronchial Hyperreactivity; Capsaicin; Chronic Disease; Elasticity; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Inflammation; Lung; Male; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin | 2005 |
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.
Topics: Acrylamides; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; CHO Cells; Cricetinae; Freund's Adjuvant; Ganglia, Spinal; Hot Temperature; Humans; Hyperalgesia; Inflammation; Motor Activity; Neurons; Pain Measurement; Patch-Clamp Techniques; Protons; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Drug; Transfection | 2005 |
Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.
Topics: Amygdala; Animals; Auditory Cortex; Behavior, Animal; Capsaicin; Conditioning, Classical; Excitatory Postsynaptic Potentials; Fear; Formaldehyde; GluK2 Kainate Receptor; Hot Temperature; Inflammation; Male; Memory; Mice; Mice, Knockout; Neuronal Plasticity; Pain; Reaction Time; Receptors, Kainic Acid | 2005 |
Molecular mechanisms of trigeminal nociception and sensation of pungency.
Topics: Animals; Capsaicin; Cell Line; Cloning, Molecular; Electrophysiology; Humans; Inflammation; Models, Biological; Models, Chemical; Rats; Temperature; Trigeminal Nerve; TRPC Cation Channels; TRPV Cation Channels | 2005 |
A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1.
Topics: Animals; Arachidonic Acids; Calcium Signaling; Capsaicin; Cell Line; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Endocannabinoids; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation; Inflammation Mediators; Ion Channel Gating; Ion Channels; Macrophage Inflammatory Proteins; Mice; Mice, Inbred BALB C; Neurons; Polyunsaturated Alkamides; Rats; Receptors, CCR1; Receptors, Chemokine; Transfection; TRPV Cation Channels | 2005 |
Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2005 |
Dopamine type 2 receptor expression and function in rodent sensory neurons projecting to the airways.
Topics: Airway Obstruction; Animals; Calcium Signaling; Capsaicin; Dopamine Agonists; Indoles; Inflammation; Male; Nodose Ganglion; Olfactory Receptor Neurons; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Drug; Trachea | 2005 |
Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse.
Topics: Animals; Capsaicin; Cells, Cultured; Freund's Adjuvant; Glycoproteins; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Ion Channels; Men; Mice; Mice, Inbred C57BL; Nociceptors; TRPV Cation Channels | 2005 |
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.
Topics: Acute Disease; Analgesics; Animals; Capsaicin; Carrageenan; Chronic Disease; Dose-Response Relationship, Drug; Edema; Formaldehyde; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Isoquinolines; Ligation; Male; Motor Activity; Osteoarthritis; Pain; Pain Measurement; Pain, Postoperative; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sciatic Nerve; Spinal Nerves; Urea | 2005 |
Vasodilatation of human gingiva and neurogenic inflammation.
Topics: Adult; Capsaicin; Dental Papilla; Female; Gingiva; Gingivitis; Humans; Inflammation; Male; Mouth Mucosa; Neurogenic Inflammation; Neurons; Periodontitis; Periodontium; Time Factors | 2005 |
Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.
Topics: Animals; Binding, Competitive; Body Temperature; Camphanes; Cannabidiol; Capsaicin; Drug Interactions; Ear, External; Gastrointestinal Motility; Inflammation; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2005 |
Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats.
Topics: Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Facial Pain; Inflammation; Jaw; Male; Muscle, Skeletal; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Valine | 2005 |
Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanisms.
Topics: Acute Disease; Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Cell Death; Extravascular Lung Water; Inflammation; Lung; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Neutrophils; Oligopeptides; Peroxidase; Positive-Pressure Respiration; Receptor, PAR-2; Up-Regulation | 2005 |
Mechanism by which peripheral galanin increases acute inflammatory pain.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Functional Laterality; Galanin; Inflammation; Male; Naphthalenes; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Time Factors | 2005 |
Dendritic cells do not transduce inflammatory stimuli via the capsaicin receptor TRPV1.
Topics: Animals; Bone Marrow Cells; Calcium; Capsaicin; Cells, Cultured; Dendritic Cells; Humans; Inflammation; Ion Channels; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Rats; Signal Transduction; Substance P; TRPV Cation Channels | 2005 |
Airway inflammation and cough sensitivity in cough-variant asthma.
Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Capsaicin; Cell Count; Diagnosis, Differential; Female; Histamine; Humans; Inflammation; Interleukin-5; Male; Nitric Oxide; Sputum | 2005 |
Induced sputum eosinophils, bronchial reactivity, and cough sensitivity in subjects with allergic rhinitis.
Topics: Acetylcholine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Capsaicin; Cough; Eosinophils; Female; Humans; Inflammation; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Spirometry; Sputum; Surveys and Questionnaires | 2005 |
[The response of the blood proteins to ablation of the capsaicin-sensitive nerves].
Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Capsaicin; Humans; Inflammation; Male; Neurons, Afferent; Rats; Rats, Wistar; Trauma, Nervous System | 2005 |
TRPV1 desensitisation and endogenous vanilloid involvement in the enhanced analgesia induced by capsaicin in inflamed tissues.
Topics: Adjuvants, Immunologic; Analgesics; Animals; Capsaicin; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Pain; Pain Measurement; TRPV Cation Channels | 2005 |
Analgesic effects of capsazepine and resiniferatoxin on bone cancer pain in mice.
Topics: Analgesics; Analysis of Variance; Animals; Bone Neoplasms; Capsaicin; Cell Line; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Freund's Adjuvant; Functional Laterality; Inflammation; Mice; Mice, Inbred C3H; Osteosarcoma; Pain; Pain Measurement; Reaction Time; Time Factors | 2006 |
Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli.
Topics: Acid Sensing Ion Channels; Animals; Behavior, Animal; Blotting, Northern; Capsaicin; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Cricetinae; Ganglia, Spinal; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Inflammation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Nerve Tissue Proteins; Neurons; Oocytes; Pain Measurement; Patch-Clamp Techniques; Physical Stimulation; Protein Structure, Tertiary; Protein Subunits; Protons; Reaction Time; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Time Factors; Transfection; Xenopus | 2005 |
Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
Topics: Albumins; Analysis of Variance; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Glycoproteins; Immunohistochemistry; Inflammation; Injections, Intradermal; Iodine Isotopes; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peroxidase; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Skin; Substance P; Tachykinins; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Neonatal chronic hind paw inflammation alters sensitization to intradermal capsaicin in adult rats: a behavioral and immunocytochemical study.
Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Capsaicin; Chronic Disease; Complex Regional Pain Syndromes; Critical Period, Psychological; Disease Models, Animal; Foot; Hyperalgesia; Immunohistochemistry; Inflammation; Male; Nerve Fibers, Unmyelinated; Neuronal Plasticity; Neurons, Afferent; Nociceptors; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Up-Regulation | 2005 |
Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes.
Topics: Arthritis, Rheumatoid; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; Cell Line, Tumor; Cells, Cultured; Chondrocalcinosis; Cytosol; Diterpenes; Hot Temperature; Humans; Inflammation; Nerve Tissue Proteins; Pyrimidinones; RNA, Messenger; Synovial Membrane; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2006 |
Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's anti-inflammatory effect.
Topics: Adrenergic Agents; Animals; Anti-Inflammatory Agents; Bee Venoms; Capsaicin; Disease Models, Animal; Diterpenes; Drug Interactions; Functional Laterality; Gene Expression; Inflammation; Leukocytes; Locus Coeruleus; Mice; Mice, Inbred ICR; Norepinephrine; Oncogene Proteins v-fos; Oxidopamine; Sciatic Neuropathy; Zymosan | 2006 |
Pivotal involvement of neurogenic mechanism in subcutaneous bee venom-induced inflammation and allodynia in unanesthetized conscious rats.
Topics: Analysis of Variance; Animals; Bee Venoms; Behavior, Animal; Capsaicin; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Pain Measurement; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Rhizotomy; Sciatic Nerve; Touch; Wakefulness | 2006 |
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs.
Topics: Animals; Capsaicin; Citric Acid; Cough; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Diterpenes; Guinea Pigs; Indomethacin; Inflammation; Isoquinolines; Male; Neurons, Afferent; Protein Kinase C; Protein Kinase Inhibitors; Receptor, PAR-2; Saline Solution, Hypertonic; Sulfonamides; TRPV Cation Channels; Trypsin | 2006 |
Analgesic activity of a non-peptide imidazolidinedione somatostatin agonist: in vitro and in vivo studies in rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Bradykinin; Capsaicin; Colforsin; Drug Interactions; Formaldehyde; Hot Temperature; Imidazolidines; In Vitro Techniques; Inflammation; Male; Nerve Fibers; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Skin; Somatostatin; Thionucleotides | 2006 |
Role of the Na+-K+-2Cl- cotransporter in the development of capsaicin-induced neurogenic inflammation.
Topics: Animals; Bumetanide; Capsaicin; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Rats; Rats, Sprague-Dawley; Reflex; Sodium-Potassium-Chloride Symporters; Vasodilation | 2006 |
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
Topics: Action Potentials; Ammonia; Animals; Antioxidants; Blood Pressure; Capsaicin; Deferoxamine; Electrophysiology; Free Radical Scavengers; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Hydroxyl Radical; Inflammation; Laryngeal Muscles; Male; Neurons, Afferent; Pepsin A; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Thiourea | 2006 |
The effects of pH on beta-endorphin and morphine inhibition of calcium transients in dorsal root ganglion neurons.
Topics: Analgesics, Opioid; Animals; beta-Endorphin; Calcium Signaling; Capsaicin; Cells, Cultured; Drug Interactions; Extracellular Fluid; Ganglia, Spinal; Hydrogen-Ion Concentration; Inflammation; Intracellular Fluid; Male; Morphine; Narcotic Antagonists; Neural Inhibition; Neurons, Afferent; Potassium; Rats; Rats, Wistar; Receptors, Opioid | 2006 |
Selective inhibitors for phosphodiesterase 3 and 4 in antigen-induced increase of cough reflex sensitivity in guinea pigs.
Topics: Allergens; Animals; Antigens; Bronchoalveolar Lavage; Capsaicin; Cough; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Imidazoles; Inflammation; Injections, Intraperitoneal; Male; Nitriles; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pyridones; Reflex | 2007 |
Blood protein reactions to ablation of capsaicin-sensitive neurons.
Topics: Albumins; Alpha-Globulins; Animals; Blood Proteins; Capsaicin; Denervation; gamma-Globulins; Inflammation; Male; Neurons, Afferent; Neurotoxicity Syndromes; Rats; Rats, Wistar; Zymosan | 2006 |
Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats.
Topics: Animals; Arachidonate 5-Lipoxygenase; Capsaicin; Carrageenan; Copper; Curcumin; Diet; Inflammation; Iron; Lipoproteins, LDL; Liver; Male; Neutrophils; Oxidation-Reduction; Rats; Rats, Wistar | 2006 |
Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity.
Topics: Animals; Biphenyl Compounds; Blotting, Western; Capsaicin; Cells, Cultured; Dinoprostone; Electrophysiology; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Hybridization; Inflammation; Injections, Spinal; Male; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Small Interfering | 2006 |
Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Capsaicin; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Glycine; Inflammation; Ion Channels; Male; Mice; Mice, Inbred ICR; Nociceptors; Oocytes; Pain; Patch-Clamp Techniques; Rats; Rats, Wistar; Sensory Receptor Cells; TRPV Cation Channels; Xenopus | 2006 |
A role for adrenomedullin as a pain-related peptide in the rat.
Topics: Adrenomedullin; Animals; Behavior, Animal; Binding Sites; Calcitonin Gene-Related Peptide; Capsaicin; Enzyme Activation; Ganglia, Spinal; Inflammation; Injections, Spinal; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Nociceptors; Pain; Phosphotransferases; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Signal Transduction | 2006 |
Impaired pain sensation in mice lacking prokineticin 2.
Topics: Animals; Behavior, Animal; Capsaicin; Ganglia, Spinal; Gastrointestinal Hormones; Hypesthesia; In Situ Hybridization; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuropeptides; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Reaction Time; Stimulation, Chemical; TRPV Cation Channels | 2006 |
Sulfur-dioxide exposure increases TRPV1-mediated responses in nodose ganglia cells and augments cough in guinea pigs.
Topics: Air Pollutants; Animals; Anti-Inflammatory Agents; Capsaicin; Cough; Dexamethasone; Guinea Pigs; Inflammation; Leukocyte Count; Lung; Male; Neutrophils; Nodose Ganglion; Respiratory Function Tests; Sulfur Dioxide; TRPV Cation Channels | 2007 |
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.
Topics: Administration, Oral; Animals; Cannabidiol; Cannabinoid Receptor Antagonists; Cannabis; Capsaicin; Chronic Disease; Dinoprostone; Freund's Adjuvant; Hyperalgesia; Inflammation; Lipid Peroxides; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar; Sciatic Neuropathy; Tumor Necrosis Factor-alpha | 2007 |
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes.
Topics: Animals; Autoimmunity; Capsaicin; Diabetes Mellitus, Type 1; Female; Inflammation; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Inbred NOD; Neurons, Afferent; Substance P; T-Lymphocytes; TRPV Cation Channels | 2006 |
Sex differences in the potency of kappa opioids and mixed-action opioids administered systemically and at the site of inflammation against capsaicin-induced hyperalgesia in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Inflammation; Injections, Intraventricular; Injections, Subcutaneous; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Inbred F344; Receptors, Opioid; Sex Factors | 2007 |
Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse.
Topics: Animals; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Capsaicin; Endotoxins; Enzyme-Linked Immunosorbent Assay; Female; Histocytochemistry; Inflammation; Interleukin-1beta; Lung; Mice; Mice, Inbred C57BL; Neurons, Afferent; Neuropeptides; Peroxidase; Radioimmunoassay; Somatostatin; Spectrophotometry; Substance P | 2007 |
AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain.
Topics: Animals; Arachidonic Acids; Capsaicin; Endocannabinoids; Immunohistochemistry; Indoles; Inflammation; Male; Pain; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Cord; TRPV Cation Channels | 2007 |
Attenuated cold sensitivity in TRPM8 null mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Calcium; Capsaicin; Cells, Cultured; Cold Temperature; Ganglia, Spinal; Inflammation; Methanol; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons, Afferent; Pain Measurement; Pyrimidinones; Reaction Time; Thermosensing; TRPM Cation Channels | 2007 |
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
Topics: Action Potentials; Analgesics; Aniline Compounds; Animals; Capsaicin; Evoked Potentials; Furans; Ganglia, Spinal; Humans; Inflammation; Kinetics; Male; Mononeuropathies; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurons; Pain; Pain Management; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sodium Channel Blockers; Sodium Channels | 2007 |
Static magnetic field-induced anti-nociceptive effect and the involvement of capsaicin-sensitive sensory nerves in this mechanism.
Topics: Analgesia; Animals; Capsaicin; Carrageenan; Chemoreceptor Cells; Diterpenes; Electromagnetic Fields; Formaldehyde; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred BALB C; Nerve Fibers; Neurons, Afferent; Pain Measurement; Postural Balance | 2007 |
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Topics: Animals; Aprotinin; Calcium Signaling; Capsaicin; Edema; Enteropeptidase; Ganglia, Spinal; Granulocytes; Humans; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptor, PAR-2; Receptors, Proteinase-Activated; Receptors, Thrombin; Recombinant Proteins; Trypsin; Trypsin Inhibitors | 2007 |
Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat.
Topics: Acute Disease; Animals; Capsaicin; Carrageenan; Diterpenes; Edema; Inflammation; Injections, Intraperitoneal; Male; Mass Spectrometry; Neurogenic Inflammation; Pituitary Adenylate Cyclase-Activating Polypeptide; Radioimmunoassay; Rats; Rats, Wistar; TRPV Cation Channels | 2007 |
Targeted disruption of the galanin gene attenuates inflammatory responses in murine skin.
Topics: Animals; Antipruritics; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Galanin; Gene Targeting; Hot Temperature; Humans; Inflammation; Mice; Mice, Knockout; Neurotransmitter Agents; Neutrophils; Skin; Substance P | 2008 |
Effect of pressure stress applied to the airway on cough-reflex sensitivity in Guinea pigs.
Topics: Animals; Biomechanical Phenomena; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Cough; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Hydroxyurea; Inflammation; Irritants; Male; Neutrophils; Reflex; Respiration, Artificial | 2008 |
Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia.
Topics: Administration, Cutaneous; Animals; Behavior, Animal; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Edema; Electric Stimulation; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Inflammation; Male; Neurogenic Inflammation; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Sciatic Nerve; Time Factors; TRPV Cation Channels | 2008 |
Reversal of pathological pain through specific spinal GABAA receptor subtypes.
Topics: Analgesics; Animals; Brain; Capsaicin; Chronic Disease; Diazepam; Disease Models, Animal; Fluorobenzenes; Formaldehyde; Ganglia, Spinal; Hot Temperature; Inflammation; Male; Mice; Neurons; Organ Specificity; Pain; Protein Isoforms; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Triazoles | 2008 |
Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber).
Topics: Acids; Animals; Capsaicin; Hyperalgesia; Inflammation; Mole Rats; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells | 2008 |
Changes in synaptic effectiveness of myelinated joint afferents during capsaicin-induced inflammation of the footpad in the anesthetized cat.
Topics: Action Potentials; Afferent Pathways; Animals; Arthralgia; Capsaicin; Cats; Female; Foot; Inflammation; Joints; Male; Mechanoreceptors; Neural Conduction; Neural Inhibition; Neuronal Plasticity; Nociceptors; Proprioception; Sensory System Agents; Sensory Thresholds; Skin; Somatosensory Disorders; Synaptic Transmission; Time Factors | 2008 |
Peripheral inflammation undermines the plasticity of the isolated spinal cord.
Topics: Analysis of Variance; Animals; Capsaicin; Conditioning, Psychological; Dose-Response Relationship, Drug; Electric Stimulation; Inflammation; Learning Disabilities; Male; Naltrexone; Narcotic Antagonists; Neuronal Plasticity; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord Injuries; Time Factors; Touch | 2008 |
Inflammation-induced increase in evoked calcium transients in subpopulations of rat dorsal root ganglion neurons.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Capsaicin; Cell Size; Cells, Cultured; Fura-2; Ganglia, Spinal; Inflammation; Male; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Pain; Plant Lectins; Potassium; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2008 |
Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Capsaicin; Capsicum; Carrageenan; Cell Movement; Edema; Exudates and Transudates; Inflammation; Interleukin-1beta; L-Lactate Dehydrogenase; Leukocytes; Male; Mice; Mice, Inbred C57BL; Peritonitis; Phytotherapy; Plant Preparations; Pleurisy; Rats; Rats, Wistar; Serum Albumin, Bovine; Tumor Necrosis Factor-alpha | 2008 |
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs.
Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cough; Eosinophils; Guinea Pigs; Histamine; Inflammation; Lidocaine; Lung; Male; Ovalbumin; Substance P | 2008 |
[Peptidergic and sensory mechanisms, parasympathetic and sympathetic nerves].
Topics: Brain Chemistry; Capsaicin; Humans; Immunochemistry; Inflammation; Muscle Contraction; Nerve Tissue Proteins; Neurons, Afferent; Parasympathetic Nervous System; Sympathetic Nervous System; Synaptic Transmission; Vasodilation | 1984 |
Effects of capsaicin on inflammation and on the substance P content of nervous tissues in rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Capsaicin; Fatty Acids, Unsaturated; Inflammation; Kinetics; Male; Mycobacterium; Nervous System; Rats; Rats, Inbred Strains; Substance P | 1983 |
Direct evidence for an axonal site of action of capsaicin.
Topics: Administration, Topical; Animals; Axons; Capsaicin; Fatty Acids, Unsaturated; Female; Inflammation; Male; Nociceptors; Rats | 1980 |
Sensory denervation with capsaicin attenuates inflammation and nociception in arthritic rats.
Topics: Animals; Arthritis; Capsaicin; Inflammation; Male; Nociceptors; Pain; Rats; Rats, Wistar; Sensory Thresholds; Time Factors | 1995 |
The 21st Meeting of the British Inflammation Research Society, "Inflammatory pain", King's College, London, 19th December, 1994.
Topics: Arthritis, Experimental; Asthma; Bronchial Hyperreactivity; Capsaicin; Humans; Inflammation; Nerve Growth Factors; Neurons, Afferent; Nitric Oxide Synthase; Pain; Receptors, Bradykinin; Spinal Cord; Up-Regulation | 1995 |
The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule.
Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Immunoglobulin G; Inflammation; Nerve Growth Factors; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins | 1995 |
A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Capsaicin; Electric Stimulation; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Morphine; Mucus; Nasal Mucosa; Pyrroles; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synapses; Thiophenes; Xylenes | 1993 |
NK1 receptors mediate neurogenic inflammatory increase in blood flow in rat airways.
Topics: Animals; Capsaicin; Inflammation; Male; Microspheres; Neurons, Afferent; Peptidyl-Dipeptidase A; Piperidines; Rats; Rats, Inbred F344; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Regional Blood Flow; Respiratory System; Respiratory Tract Diseases; Substance P; Tachykinins; Vasodilation | 1993 |
Inhibition of neurogenic inflammation in the meninges by a non-peptide NK1 receptor antagonist, RP 67580.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Dura Mater; Guinea Pigs; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Meninges; Migraine Disorders; Rats; Rats, Wistar; Stereoisomerism; Substance P | 1993 |
Sensitization of insensitive branches of C nociceptors in human skin.
Topics: Adult; Capsaicin; Electric Stimulation; Electrophysiology; Humans; Hyperalgesia; Inflammation; Male; Mechanoreceptors; Mustard Plant; Nociceptors; Plant Extracts; Plant Oils; Skin | 1994 |
Inflammation and hyperalgesia in rats neonatally treated with capsaicin: effects on two classes of nociceptive neurons in the superficial dorsal horn.
Topics: Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Electric Stimulation; Female; Freund's Adjuvant; Hyperalgesia; Immunohistochemistry; Inflammation; Microscopy, Electron; Nerve Fibers; Neurons, Afferent; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
Carrageenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Capsaicin; Carrageenan; Denervation; Female; Foot; gamma-Aminobutyric Acid; Immunohistochemistry; Inflammation; Nerve Fibers; Neurons, Afferent; Nociceptors; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Tissue Fixation | 1994 |
Effects of CGRP in different models of mouse ear inflammation.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Cantharidin; Capsaicin; Croton Oil; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Inflammation; Male; Mice; Tetradecanoylphorbol Acetate | 1994 |
Effects of capsaicin on the airway responses to inhaled endotoxin in the guinea pig.
Topics: Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capsaicin; Endotoxins; Escherichia coli; Glycopeptides; Guinea Pigs; Histamine; Inflammation; Lipopolysaccharides; Macrophages; Male; Neprilysin; Neutrophils; Premedication; Propranolol; Trachea | 1994 |
Mechanisms of activation of the pituitary-adrenal axis by tissue injury in the rat.
Topics: Acute-Phase Reaction; Adrenocorticotropic Hormone; Afferent Pathways; Animals; Animals, Newborn; Arousal; Capsaicin; Corticosterone; Hypothalamo-Hypophyseal System; Inflammation; Interleukin-6; Male; Nociceptors; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Turpentine | 1994 |
Capsaicin pretreatment increases inflammatory response to intratracheal instillation of endotoxin in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capsaicin; Drug Synergism; Inflammation; Instillation, Drug; Lipopolysaccharides; Lung; Male; Nerve Fibers; Neutrophils; Rats; Rats, Sprague-Dawley; Trachea; Tumor Necrosis Factor-alpha | 1993 |
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs.
Topics: Aerosols; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; Inflammation; Lung; Male; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pulmonary Circulation; Receptors, Neurokinin-2; Vascular Resistance | 1993 |
Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis.
Topics: Aerosols; Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Indomethacin; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Stress, Mechanical; Trachea | 1993 |
Vanilloids. 1. Analogs of capsaicin with antinociceptive and antiinflammatory activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Croton Oil; Homovanillic Acid; Hot Temperature; Inflammation; Male; Mice; Mice, Inbred ICR; Molecular Structure; Pain Measurement; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1993 |
Characterization of neurogenic inflammation in the airways of two highly inbred rat strains.
Topics: Animals; Benzamides; Blood Pressure; Bronchi; Capillary Permeability; Capsaicin; Cimetidine; Coloring Agents; Dose-Response Relationship, Drug; Evans Blue; Histamine Antagonists; Indoles; Inflammation; Isoindoles; Methysergide; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrilamine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Neurokinin-1; Serotonin; Serotonin Antagonists; Substance P; Trachea | 1995 |
[Effect of blocking capsaicin-sensitive nerves on development of exudate reaction in immune response and aseptic inflammation].
Topics: Animals; Capsaicin; Exudates and Transudates; Inflammation; Male; Mice; Mice, Inbred BALB C; Nerve Block; Neurons; Vaccines | 1995 |
Inflammatory cellular influx follows capsaicin nasal challenge.
Topics: Adult; Capsaicin; Female; Humans; Hypersensitivity; Inflammation; Leukocyte Count; Leukocytes, Mononuclear; Male; Middle Aged; Nasal Mucosa; Neutrophils; Rhinitis | 1996 |
Sensory denervation by neonatal capsaicin treatment exacerbates Mycoplasma pulmonis infection in rat airways.
Topics: Animals; Animals, Newborn; Capsaicin; Denervation; Epithelium; Inflammation; Lung Diseases; Male; Mucous Membrane; Mycoplasma Infections; Neovascularization, Pathologic; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P; Trachea | 1996 |
The effect of intra-articular capsaicin on nerve fibres within the synovium of the rat knee joint.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Inflammation; Injections, Intra-Articular; Knee Joint; Leukocytes, Mononuclear; Male; Nerve Fibers; Nerve Tissue Proteins; Neuropeptide Y; Neutrophils; Rats; Rats, Wistar; Substance P; Synovial Membrane; Thiolester Hydrolases; Ubiquitin Thiolesterase | 1996 |
Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Antitussive Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inflammation; Male; Regression Analysis; Respiratory System; Smoke; Thiazoles; Thiazolidines | 1996 |
Influence of inflammation or disconnection from peripheral target tissue on the capsaicin sensitivity of rat dorsal root ganglion sensory neurones.
Topics: Animals; Biological Transport; Calcium; Capsaicin; Cells, Cultured; Denervation; Drug Resistance; Ganglia, Spinal; Inflammation; Ion Channel Gating; Ion Channels; Nerve Growth Factors; Neurons, Afferent; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1996 |
The vasodilator component of neurogenic inflammation is caused by a special subclass of heat-sensitive nociceptors in the skin of the pig.
Topics: Animals; Axons; Capsaicin; Electric Stimulation; Hot Temperature; Humans; Inflammation; Mechanoreceptors; Nerve Fibers; Nociceptors; Regional Blood Flow; Saphenous Vein; Skin; Swine | 1996 |
Role of C fibers in the inflammatory response to intratracheal lipopolysaccharide.
Topics: Animals; Capsaicin; Female; Inflammation; Lipopolysaccharides; Nerve Fibers; Pregnancy; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Trachea | 1996 |
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P | 1996 |
PACAP occurs in sensory nerve fibers and participates in ocular inflammation in the rabbit.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Capsaicin; Ciliary Body; Eye; Eye Injuries; Inflammation; Iris; Nerve Fibers; Neurons, Afferent; Neuropeptides; Neurotransmitter Agents; Ocular Physiological Phenomena; Organ Specificity; Pituitary Adenylate Cyclase-Activating Polypeptide; Rabbits | 1996 |
Dose-dependent protective effect of BPC 157 on capsaicin-induced rhinitis in rats.
Topics: Administration, Intranasal; Animals; Capsaicin; Cell Count; Cell Degranulation; Dose-Response Relationship, Drug; Inflammation; Injections, Intraperitoneal; Lymphocytes; Male; Mast Cells; Nasal Mucosa; Nasal Provocation Tests; Neutrophils; Peptide Fragments; Proteins; Rats; Rats, Wistar; Rhinitis; Sodium Chloride | 1997 |
Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation.
Topics: Adenoviruses, Human; Animals; Capillary Permeability; Capsaicin; Dexamethasone; Ficusin; Gene Transfer Techniques; Genetic Vectors; Glucocorticoids; Hot Temperature; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Photosensitizing Agents; Piperidines; Protein Denaturation; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Respiratory System; Substance P; Ultraviolet Rays | 1997 |
Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions.
Topics: Animals; Animals, Newborn; Capsaicin; Cerebral Cortex; Chymases; Denervation; Dura Mater; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine Antagonists; Inflammation; Male; Mast Cells; Methylhistamines; Nerve Fibers; Neurons, Afferent; Nippostrongylus; Piperidines; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Serine Endopeptidases; Strongylida Infections | 1997 |
Ocular inflammation induced by electroconvulsive treatment: contribution of nitric oxide and neuropeptides mobilized from C-fibres.
Topics: Animals; Aqueous Humor; Capsaicin; Electroconvulsive Therapy; Eye Diseases; Inflammation; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Receptors, Tachykinin; Substance P | 1997 |
Effects of neurokinin depletion on airway inflammation induced by chronic antigen exposure.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Antigens; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; CD4 Lymphocyte Count; Edema; Elasticity; Guinea Pigs; Inflammation; Lung; Lung Compliance; Male; Ovalbumin; Tachykinins | 1997 |
Plasma extravasation and neuropeptide release in human skin as measured by intradermal microdialysis.
Topics: Adult; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Forearm; Histamine; Humans; Inflammation; Iontophoresis; Microdialysis; Pain; Skin; Substance P; Time Factors | 1997 |
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles | 1997 |
Plasma protein extravasation induced in the rat dura mater by stimulation of the parasympathetic sphenopalatine ganglion.
Topics: Acetylcholine; Afferent Pathways; Animals; Atropine; Axons; Blood Pressure; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Disease Models, Animal; Dura Mater; Electric Stimulation; Exudates and Transudates; Ganglia, Parasympathetic; Inflammation; Injections, Intra-Arterial; Male; Migraine Disorders; Neurons, Afferent; Parasympathetic Fibers, Postganglionic; Parasympathomimetics; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serum Albumin, Bovine; Substance P | 1997 |
Inflammatory mediators at acidic pH activate capsaicin receptors in cultured sensory neurons from newborn rats.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Cells, Cultured; Coculture Techniques; Dinoprostone; Drug Synergism; Ganglia, Spinal; Hippocampus; Hydrogen-Ion Concentration; Inflammation; Ion Channel Gating; Neuroglia; Neurons, Afferent; Rats; Receptors, Drug; Serotonin; Stimulation, Chemical | 1998 |
Role of sensory innervation and mast cells in neurogenic plasma protein exudation into the airway lumen.
Topics: Analysis of Variance; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Exudates and Transudates; Histamine; Inflammation; Mast Cells; Neuropeptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Substance P; Trachea; Vagus Nerve | 1997 |
Neuropeptide regulation of proinflammatory cytokine responses.
Topics: Animals; Capsaicin; Cytokines; Endotoxins; Female; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Spleen; Tachykinins; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1998 |
Effects of neurotoxins and hindpaw inflammation on opioid receptor immunoreactivities in dorsal root ganglia.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Ganglia, Spinal; Hindlimb; Immunohistochemistry; Inflammation; Male; Neurotoxins; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Opioid; Spinal Cord; Tissue Distribution | 1998 |
Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice.
Topics: Abdominal Muscles; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Cyclooxygenase Inhibitors; Diclofenac; Formaldehyde; Inflammation; Male; Meloxicam; Mice; Morphine; Muscle Contraction; Pain; Pain Measurement; Reaction Time; Thiazines; Thiazoles | 1998 |
Effects of airway inflammation on cough response in the guinea pig.
Topics: Animals; Antitussive Agents; Benzamides; Bronchoalveolar Lavage Fluid; Capsaicin; Codeine; Cough; Dipeptides; Female; Guinea Pigs; Indoles; Inflammation; Peptides, Cyclic; Piperidines; Quinuclidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Respiratory Hypersensitivity; Respiratory Tract Diseases | 1998 |
Systemic anti-inflammatory effect induced by counter-irritation through a local release of somatostatin from nociceptors.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Dextrans; Edema; Female; Inflammation; Rats; Rats, Wistar; Sensory Receptor Cells; Somatostatin | 1998 |
A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: evidence for an endogenous capsaicin-like substance.
Topics: Animals; Capsaicin; Carrageenan; Functional Laterality; Hindlimb; Hyperalgesia; Inflammation; Male; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reflex; Spinal Cord | 1998 |
VCAM-1 expression on human dermal microvascular endothelial cells is directly and specifically up-regulated by substance P.
Topics: Capsaicin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Inflammation; Neuroimmunomodulation; RNA, Messenger; Skin; Substance P; T-Lymphocytes; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 1999 |
The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Capsaicin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Excipients; Hindlimb; Hyperalgesia; Inflammation; Inflammation Mediators; Male; Nociceptors; Oxytocics; Pain; Pain Threshold; Rats; Rats, Wistar; Thionucleotides; Ultraviolet Rays | 1999 |
Effects of the orally active non-peptide bradykinin B2 receptor antagonist, FR173657, on plasma extravasation in guinea pig airways.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Glycopeptides; Guinea Pigs; Inflammation; Male; Ovalbumin; Photometry; Protease Inhibitors; Quinolines; Respiratory System; Trachea | 1999 |
The inflammatory reaction induced by formalin in the rat paw.
Topics: Anesthetics, Local; Animals; Blood Pressure; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Inflammation Mediators; Kininogens; Lidocaine; Male; Neuropeptides; Rats; Rats, Wistar; Serum Albumin; Time Factors | 1999 |
Response properties of trigeminal brain stem neurons with input from dura mater encephali in the rat.
Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Dura Mater; Electric Stimulation; Histamine; Inflammation; Male; Mechanoreceptors; Microelectrodes; Neurons; Rats; Rats, Wistar; Serotonin; Trigeminal Nuclei; Trigeminal Nucleus, Spinal | 1999 |
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2 | 1999 |
Jaw electromyographic activity induced by the application of algesic chemicals to the rat tooth pulp.
Topics: Animals; Bradykinin; Capsaicin; Dental Pulp; Electromyography; Evans Blue; Inflammation; Jaw; Male; Masseter Muscle; Mustard Plant; Naloxone; Narcotic Antagonists; Neutrophils; Pain; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley | 1999 |
Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner.
Topics: Amidines; Animals; Capsaicin; Cells, Cultured; Densitometry; Fluorescent Dyes; Foot; Ganglia, Spinal; Inflammation; Male; Nerve Growth Factors; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 1999 |
Respiratory tract inflammation during the induction of chronic bronchitis in rats: role of C-fibres.
Topics: Animals; Animals, Newborn; Bronchi; Bronchitis; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Chronic Disease; Female; Inflammation; Macrophages, Alveolar; Maternal Exposure; Nasal Lavage Fluid; Nerve Fibers; Neutrophils; Pregnancy; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Sulfur Dioxide; Tachykinins | 1999 |
Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats.
Topics: Animals; Bicuculline; Capsaicin; Femoral Nerve; Functional Laterality; Inflammation; Injections, Intradermal; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Reflex; Regional Blood Flow; Rhizotomy; Sciatic Nerve; Skin; Spinal Nerve Roots; Time Factors | 1999 |
Impaired nociception and pain sensation in mice lacking the capsaicin receptor.
Topics: Animals; Body Temperature; Calcium; Capsaicin; Cells, Cultured; Diterpenes; Ganglia, Spinal; Gene Targeting; Hot Temperature; Hydrogen-Ion Concentration; Inflammation; Mice; Mice, Knockout; Nerve Fibers; Neurons; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Receptors, Drug; Spinal Cord; TRPV Cation Channels | 2000 |
Interactions of inflammatory mediators and low pH not influenced by capsazepine in rat cutaneous nociceptors.
Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Drug Interactions; Ganglia, Spinal; Hydrogen-Ion Concentration; Inflammation; Inflammation Mediators; Male; Nerve Fibers; Nociceptors; Oxytocics; Protons; Rats; Rats, Wistar; Serotonin; Signal Transduction; Skin | 2000 |
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Behavior, Animal; Capsaicin; Carrageenan; Cells, Cultured; Electrophysiology; Endocannabinoids; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Targeting; Hot Temperature; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Polyunsaturated Alkamides; Receptors, Drug; Stem Cells; TRPV Cation Channels | 2000 |
Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances.
Topics: Animals; Capsaicin; Cell Line; Cells, Cultured; Dinoprostone; Eicosanoids; Ganglia, Spinal; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Ion Channel Gating; Leukotriene B4; Leukotrienes; Ligands; Lipid Peroxides; Lipoxygenase; Molecular Structure; Neurons, Afferent; Prostaglandin D2; Prostaglandin H2; Prostaglandins H; Rats; Receptors, Drug; Structure-Activity Relationship | 2000 |
Implications of oxidative stress and inflammatory process in the cytotoxicity of capsaicin in human endothelial cells: lack of DNA strand breakage.
Topics: Capsaicin; Cells, Cultured; DNA Damage; DNA Fragmentation; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Protein Synthesis Inhibitors; Thiobarbituric Acid Reactive Substances | 2000 |
Prostaglandin E(2)-mediated sensitization of rat sensory neurons is not altered by nerve growth factor.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic AMP; Dinoprostone; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley | 2000 |
Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.
Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Colon; Cyclophosphamide; Cystitis; Female; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Mustard Plant; Nociceptors; Pain; Physical Stimulation; Plant Extracts; Plant Oils; Receptors, Neurokinin-1; Substance P; Urinary Bladder; Visceral Afferents | 2000 |
Toward a new anti-inflammatory and analgesic agent.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Bradykinin Receptor Antagonists; Capsaicin; Cyclooxygenase 2; Formaldehyde; Inflammation; Interleukin-1; Isoenzymes; Mice; Mice, Knockout; Pain; Prostaglandin-Endoperoxide Synthases; Receptor, Bradykinin B1; Receptors, Bradykinin; Receptors, Neurokinin-1; Shock, Septic | 2000 |
Effects of topically applied capsaicin cream on neurogenic inflammation and thermal sensitivity in rats.
Topics: Administration, Topical; Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Pain Threshold; Rats; Rats, Sprague-Dawley; Substance P | 2000 |
Systemic anti-inflammatory effect of somatostatin released from capsaicin-sensitive vagal and sciatic sensory fibres of the rat and guinea-pig.
Topics: Afferent Pathways; Animals; Anti-Inflammatory Agents; Blood Pressure; Capillary Permeability; Capsaicin; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; Female; Guanethidine; Guinea Pigs; Heart Rate; Hindlimb; Inflammation; Mustard Plant; Nerve Fibers; Pipecuronium; Plant Extracts; Plant Oils; Rats; Rats, Wistar; Sciatic Nerve; Skin; Somatostatin; Vagus Nerve | 2000 |
Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo.
Topics: Animals; Calcium; Capsaicin; Cell Communication; Electric Stimulation; Guinea Pigs; Inflammation; Male; Membrane Potentials; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Substance P; Trigeminal Ganglion | 2000 |
Responses of nerve fibres of the rat saphenous nerve neuroma to mechanical and chemical stimulation: an in vitro study.
Topics: Animals; Capsaicin; Electrophysiology; Hydrogen-Ion Concentration; Hypertonic Solutions; Inflammation; Nerve Endings; Nerve Fibers; Nerve Regeneration; Neural Conduction; Neuroma; Nociceptors; Physical Stimulation; Rats; Stimulation, Chemical; Tachyphylaxis | 2000 |
Nociceptive neuroendocrine negative feedback control of neurogenic inflammation activated by capsaicin in the rat paw: role of the adrenal medulla.
Topics: Adrenal Medulla; Animals; Bradykinin; Capillary Permeability; Capsaicin; Denervation; Electric Stimulation; Feedback; Hindlimb; Hypothalamo-Hypophyseal System; Inflammation; Joints; Male; Neurons, Afferent; Neurosecretory Systems; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Synovial Fluid; Vagotomy | 2000 |
Capsaicin inhibits platelet-activating factor-induced cytosolic Ca2+ rise and superoxide production.
Topics: Apoptosis; Biological Transport; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Capsaicin; Cytosol; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Inflammation; Platelet Activating Factor; Superoxides; Thapsigargin; Type C Phospholipases; Up-Regulation | 2000 |
Antinociceptive activity of ricinoleic acid, a capsaicin-like compound devoid of pungent properties.
Topics: Administration, Topical; Animals; Capsaicin; Carrageenan; Conjunctiva; Guinea Pigs; Hindlimb; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Ricinoleic Acids | 2000 |
Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor.
Topics: Animals; Capsaicin; Gene Targeting; Inflammation; Male; Mice; Mice, Inbred BALB C; Mutagenesis; Pain; Pain Threshold; Plasma; Receptors, Neuropeptide Y; Substance P | 2001 |
Development and sequels of intestinal inflammation in nematode-infected rats: role of mast cells and capsaicin-sensitive afferents.
Topics: Animals; Capsaicin; Cell Count; Inflammation; Intestine, Small; Ketotifen; Mast Cells; Neurons, Afferent; Nippostrongylus; Peroxidase; Rats; Strongylida Infections | 2000 |
Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity.
Topics: Afferent Pathways; Animals; Axonal Transport; Capsaicin; Colchicine; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Inflammation; Male; Nerve Endings; Oligodeoxyribonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sciatic Nerve; Transcription, Genetic | 2001 |
Characterization of increased cough sensitivity after antigen challenge in guinea pigs.
Topics: Allergens; Animals; Antigens; Bronchial Provocation Tests; Capsaicin; Cough; Eosinophils; Guinea Pigs; Hypersensitivity; Inflammation | 2001 |
Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Fixatives; Formaldehyde; Ganglionic Stimulants; Inflammation; Magnesium Sulfate; Mice; Mice, Transgenic; Morphine; Naloxone; Narcotic Antagonists; Nicotine; Opioid-Related Disorders; Pain; Substance Withdrawal Syndrome | 2001 |
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine.
Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Hexamethonium; Inflammation; Knee Joint; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nicotine; Nociceptors; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid; Sciatic Nerve; Time Factors | 2001 |
Role of calcitonin gene-related peptide and kinins in post-ischemic intestinal reperfusion.
Topics: Animals; Bradykinin Receptor Antagonists; Calcitonin Gene-Related Peptide; Capsaicin; Duodenum; Inflammation; Intestinal Mucosa; Ischemia; Kinins; Male; Mesenteric Arteries; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Reperfusion; Reperfusion Injury; Tachykinins; Time Factors | 2001 |
Role of capsaicin-sensitive afferents in fever and cytokine responses during systemic and local inflammation in rats.
Topics: Afferent Pathways; Animals; Animals, Newborn; Atrophy; Capsaicin; Cytokines; Denervation; Exploratory Behavior; Fever; Foot; Freund's Adjuvant; Inflammation; Injections, Intraperitoneal; Interleukin-6; Lipopolysaccharides; Lung; Neurons, Afferent; Nociceptors; Peritonitis; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Urinary Bladder | 2001 |
Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Capsaicin; Cells, Cultured; Chemokines; Fluorescent Dyes; Ganglia, Spinal; HIV Envelope Protein gp120; Hyperalgesia; Inflammation; Intracellular Fluid; Male; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, CCR4; Receptors, Chemokine; Receptors, CXCR4; RNA, Messenger; Substance P | 2001 |
Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blepharitis; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Cells, Cultured; Drug Synergism; Female; Ganglia, Spinal; Guinea Pigs; Inflammation; Lectins; Male; Neurokinin A; Neurons; Plant Extracts; Plant Lectins; Rats; Ricinoleic Acids; Seeds; Substance P | 2001 |
NMDA or non-NMDA receptor antagonists attenuate increased Fos expression in spinal dorsal horn GABAergic neurons after intradermal injection of capsaicin in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blotting, Western; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Functional Laterality; gamma-Aminobutyric Acid; Inflammation; Injections, Intradermal; Interneurons; Male; Membrane Potentials; Neural Conduction; Neural Inhibition; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 2001 |
Nitric oxide synthase in spinal cord central sensitization following intradermal injection of capsaicin.
Topics: Animals; Capsaicin; Enzyme Inhibitors; Inflammation; Injections, Intradermal; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pain Measurement; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord | 2001 |
Effects of PGE(2) on neurons from rat dorsal root ganglia in intact and adjuvant-inflamed rats: role of NGF on PGE(2)-induced depolarization.
Topics: Action Potentials; Animals; Arthritis, Experimental; Bradykinin; Capsaicin; Cells, Cultured; Dinoprostone; Freund's Adjuvant; Ganglia, Spinal; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Rats; Rats, Wistar; Sensory Thresholds; Tachyphylaxis | 2001 |
Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones.
Topics: Action Potentials; Animals; Capsaicin; Cells, Cultured; Cold Temperature; Cryotherapy; Ganglia, Spinal; Hypothermia, Induced; Inflammation; Neurons, Afferent; Nociceptors; Pain; Pain Management; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Drug; TRPV Cation Channels | 2002 |
Attenuation of thermal nociception and hyperalgesia by VR1 blockers.
Topics: Animals; Calcium; Capsaicin; Dose-Response Relationship, Drug; Electrophysiology; Glycine; Hot Temperature; Hyperalgesia; Inflammation; Knee; Male; Mice; Mice, Inbred ICR; Mustard Plant; Neurons; Pain; Pain Threshold; Peptoids; Plant Extracts; Plant Oils; Rats; Rats, Wistar; Receptors, Drug; Recombinant Proteins; Stress, Mechanical; Time Factors; Xenopus | 2002 |
Nociceptive behaviour induced by dental application of irritants to rat incisors: a new model for tooth inflammatory pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Capsaicin; Crowns; Cyclooxygenase Inhibitors; Dental Pulp Cavity; Disease Models, Animal; Drug Interactions; Female; Formaldehyde; Gingiva; Inflammation; Male; Meloxicam; Morphine; Naloxone; Narcotic Antagonists; Nerve Fibers; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles; Toothache | 2002 |
Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cell Count; Cyclohexylamines; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Indoles; Inflammation; Macrophages; Male; Neurokinin A; Peptides, Cyclic; Receptors, Tachykinin; Substance P; Tachykinins; Time Factors; Vasodilator Agents | 2002 |
Capsaicin-sensitive nerve fibres induce epithelial cell proliferation, inflammatory cell immigration and transforming growth factor-alpha expression in the rat colonic mucosa in vivo.
Topics: Animals; Blotting, Western; Bromodeoxyuridine; Calcitonin Gene-Related Peptide; Capsaicin; Cell Division; Colon; Denervation; Goblet Cells; Immunohistochemistry; Inflammation; Intestinal Mucosa; Male; Nerve Fibers; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Transforming Growth Factor alpha | 2002 |
Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats.
Topics: Action Potentials; Afferent Pathways; Animals; Capsaicin; Carrageenan; Dose-Response Relationship, Drug; Inflammation; Injections, Spinal; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neural Inhibition; Nociceptors; Pain; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Drug | 2002 |
Stimulation of deep somatic tissue with capsaicin produces long-lasting mechanical allodynia and heat hypoalgesia that depends on early activation of the cAMP pathway.
Topics: Adenylyl Cyclase Inhibitors; Animals; Behavior, Animal; Capsaicin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hot Temperature; Inflammation; Injections; Joints; Kinetics; Male; Muscles; Organ Specificity; Pain; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Skin; Stress, Mechanical | 2002 |
A study of chemically induced acute inflammation in the skin of the rat.
Topics: Animals; Benzene; Capsaicin; Cell Count; Ear; Edema; Inflammation; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Skin; Sympathetic Nervous System | 1977 |
Delta- and kappa-opioid agonists inhibit plasma extravasation induced by bradykinin in the knee joint of the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Bradykinin; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Inflammation; Joints; Male; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1992 |
Immunoneutralization studies with calcitonin gene-related peptide.
Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Emptying; Gastric Mucosa; Humans; Immune Sera; Immunization; Inflammation; Peptide Fragments; Rats; Rats, Inbred Strains; RNA, Messenger; Somatostatin | 1992 |
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation | 1992 |
Neonatal capsaicin treatment attenuates spinal Fos activation and dynorphin gene expression following peripheral tissue inflammation and hyperalgesia.
Topics: Animals; Animals, Newborn; Capsaicin; Dynorphins; Enkephalins; Female; Foot Diseases; Gene Expression; Hyperalgesia; Inflammation; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1992 |
Substance P-immunoreactive sensory axons in the rat respiratory tract: a quantitative study of their distribution and role in neurogenic inflammation.
Topics: Animals; Arterioles; Axons; Bronchi; Capsaicin; Ganglia; Histocytochemistry; Inflammation; Male; Muscle, Smooth, Vascular; Neurons, Afferent; Rats; Rats, Inbred F344; Respiratory System; Substance P; Trachea; Vagotomy; Venules | 1992 |
Evidence for an increase in the release of CGRP from sensory nerves during inflammation.
Topics: Animals; Axonal Transport; Calcitonin Gene-Related Peptide; Capsaicin; Freund's Adjuvant; Hindlimb; Inflammation; Neurons, Afferent; Potassium; Rats; Sciatic Nerve; Skin; Spinal Cord; Time Factors | 1992 |
Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Edema; In Vitro Techniques; Inflammation; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1992 |
The quantitative contribution of nitric oxide and sensory nerves to bradykinin-induced inflammation in rat skin microvasculature.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Bradykinin; Capsaicin; Female; Inflammation; Male; Microcirculation; Molecular Sequence Data; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Stereoisomerism | 1992 |
The partial inhibition of inflammatory responses induced by capsaicin using the Fab fragment of a selective calcitonin gene-related peptide antiserum in rabbit skin.
Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Edema; Immune Sera; Immunoglobulin Fab Fragments; Immunoglobulin G; Inflammation; Male; Rabbits; Skin | 1992 |
Effect of synthetic tachykinin analogues on airway microvascular leakage in rats and guinea-pigs: evidence for the involvement of NK-1 receptors.
Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Guinea Pigs; Inflammation; Male; Microcirculation; Neuropeptides; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory System; Serotonin; Tachykinins | 1991 |
Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antibodies; Capsaicin; Central Nervous System; Corticotropin-Releasing Hormone; Denervation; Eating; Fever; Flurbiprofen; Inflammation; Injections, Intramuscular; Kinetics; Male; Oxygen Consumption; Peripheral Nerves; Propranolol; Rats; Rats, Inbred Strains; Turpentine | 1991 |
A bradykinin (BK)1 receptor antagonist blocks capsaicin-induced ear inflammation in mice.
Topics: Animals; Bradykinin; Capsaicin; Ear, External; Edema; Inflammation; Male; Mice; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P | 1990 |
Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Glycopeptides; In Vitro Techniques; Inflammation; Male; Neurons, Afferent; Neuropeptides; Rats; Rats, Inbred F344; Saline Solution, Hypertonic; Substance P; Trachea | 1990 |
Capsaicin pretreatment modifies hydrogen sulphide-induced pulmonary injury in rats.
Topics: Animals; Capsaicin; Hydrogen Sulfide; Inflammation; Lung; Lung Diseases; Male; Microscopy, Electron, Scanning; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P | 1990 |
Serotonin modulates substance P-induced plasma extravasation and vasodilatation in rat skin by an action through capsaicin-sensitive primary afferent nerves.
Topics: Afferent Pathways; Animals; Blister; Capillary Permeability; Capsaicin; Inflammation; Male; Plasma; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin; Skin; Substance P; Time Factors; Vasodilation | 1990 |
Modulation of a peripheral inflammatory response to substance P by locally administered opioid receptor agonists.
Topics: Administration, Topical; Amino Acid Sequence; Animals; Blister; Capillary Permeability; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Inflammation; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Perfusion; Peripheral Nerves; Rats; Skin; Substance P; Vasodilation | 1990 |
Inflammatory responses induced by substance P in rat paw.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Female; Histamine Release; Inflammation; Male; Rats; Rats, Inbred Strains; Substance P | 1990 |
Neurogenic inflammation induced by capsaicin in patients with psoriasis.
Topics: Administration, Cutaneous; Adult; Age Factors; Capsaicin; Dose-Response Relationship, Drug; Erythema; Forearm; Humans; Inflammation; Psoriasis; Scleroderma, Systemic; Skin; Substance P | 1991 |
Mechanical irritation induces neurogenic inflammation in the rat urethra.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglionectomy; Inflammation; Neurons, Afferent; Rats; Rats, Inbred Strains; Stress, Mechanical; Substance P; Urethra; Urethritis; Urinary Catheterization | 1991 |
Potent anti-inflammatory action of calcitonin gene-related peptide.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Cricetinae; Edema; Female; Histamine; Humans; Inflammation; Leukotriene B4; Male; Middle Aged; Mouth Mucosa; Rats; Serotonin; Skin; Skin Physiological Phenomena; Substance P | 1991 |
Involvement of substance P in hyperalgesia induced by intrathecal galanin.
Topics: Animals; Antibodies, Monoclonal; Behavior, Animal; Capsaicin; Carrageenan; Galanin; Guinea Pigs; Ileum; In Vitro Techniques; Inflammation; Injections, Spinal; Male; Muscle, Smooth; Neurokinin A; Nociceptors; Pain; Peptides; Rats; Rats, Inbred Strains; Substance P | 1991 |
Neurogenic component of different models of acute inflammation in the rat knee joint.
Topics: Animals; Capsaicin; Carrageenan; Disease Models, Animal; Formaldehyde; Hindlimb; Inflammation; Joints; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Substance P; Uric Acid | 1991 |
Ruthenium red and capsaicin induce a neurogenic inflammatory response in the rabbit eye: effects of omega-conotoxin GVIA and tetrodotoxin.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Capsaicin; Eye; Female; Inflammation; Intraocular Pressure; Male; Miosis; Neurokinin A; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Rabbits; Ruthenium Red; Substance P; Tetrodotoxin | 1991 |
Trigeminal sensory fiber stimulation induces morphological changes reflecting secretion in rat dura mater mast cells.
Topics: Animals; Capsaicin; Cytoplasmic Granules; Dura Mater; Electric Stimulation; Humans; Inflammation; Male; Mast Cells; Neurons, Afferent; Rats; Rats, Inbred Strains; Tongue; Trigeminal Ganglion; Trigeminal Nerve; Vascular Headaches | 1991 |
Systemic capsaicin and olvanil reduce the acute algogenic and the late inflammatory phase following formalin injection into rodent paw.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Electrophysiology; Foot; Formaldehyde; Indomethacin; Inflammation; Mice; Morphine; Neurons; Pain; Spinal Cord | 1991 |
The effect of neonatal treatment with capsaicin on focal arteriolar insudation.
Topics: Animals; Animals, Newborn; Arterioles; Body Weight; Capsaicin; Dilatation, Pathologic; Focal Infection; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains | 1991 |
Further behavioral evidence that colorectal distension is a 'noxious' visceral stimulus in rats.
Topics: Animals; Avoidance Learning; Capsaicin; Colon; Inflammation; Male; Morphine; Motor Activity; Muscle Contraction; Muscle, Smooth; Pain; Rats; Rats, Inbred Strains; Rectum; Turpentine | 1991 |
Biosynthesis and release of tachykinins from rat sensory neurons in culture.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Chromatography, High Pressure Liquid; Ganglia, Spinal; Inflammation; Neurons, Afferent; Neuropeptides; Nifedipine; Pain; Potassium; Radioimmunoassay; Rats; RNA, Messenger; Tachykinins; Trigeminal Ganglion | 1991 |
Neurogenic inflammation of the rat trachea: fate of neutrophils that adhere to venules.
Topics: Analysis of Variance; Animals; Capsaicin; Cell Adhesion; Chemotaxis, Leukocyte; Female; Glycopeptides; Inflammation; Muscle, Smooth; Neutrophils; Peroxidase; Rats; Regression Analysis; Trachea; Vagus Nerve; Venules | 1990 |
Mycoplasma pulmonis infections cause long-lasting potentiation of neurogenic inflammation in the respiratory tract of the rat.
Topics: Ammonia; Animals; Antigens, Bacterial; Capillary Permeability; Capsaicin; Epithelium; Inflammation; Lymphoid Tissue; Microscopy, Electron; Mycoplasma; Nervous System; Pneumonia, Mycoplasma; Rats; Trachea | 1991 |
Involvement of capsaicin-sensitive neurones in hyperalgesia and enhanced opioid antinociception in inflammation.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Freund's Adjuvant; Hyperalgesia; Inflammation; Injections, Subcutaneous; Male; Morphine; Narcotics; Neurons; Nociceptors; Pressure; Rats; Rats, Inbred Strains; Time Factors; Vasodilation | 1990 |
Denervation-induced inflammation in the rat.
Topics: Animals; Bupivacaine; Capsaicin; Denervation; Electric Stimulation; Foot; Hindlimb; Inflammation; Male; Peripheral Nerves; Rats; Sciatic Nerve | 1990 |
Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Capsaicin; Carrageenan; Cell Movement; Edema; Guinea Pigs; Inflammation; Leukocytes; Male; Mice; Otitis; Platelet Aggregation Inhibitors; Pleurisy; Rats; Rats, Inbred Strains; Vanillic Acid | 1990 |
Neurogenic inflammation, vascular permeability, and mast cells. Capsaicin desensitization fails to influence IgE-anti-DNP induced vascular permeability in rat airways.
Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Desensitization, Immunologic; Dinitrophenols; Immunization, Passive; Immunoglobulin E; Inflammation; Male; Mast Cells; Rats; Rats, Inbred Strains; Respiratory System; Respiratory Tract Diseases; Skin; Skin Tests; Specific Pathogen-Free Organisms; Trachea | 1990 |
Motor and inflammatory effect of hyperosmolar solutions on the rat urinary bladder in relation to capsaicin-sensitive sensory nerves.
Topics: Animals; Blood Proteins; Capsaicin; Ganglionectomy; Hypertonic Solutions; In Vitro Techniques; Inflammation; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Inbred Strains; Urinary Bladder; Urination | 1990 |
The effect of substance P on the regional lymph node antibody response to antigenic stimulation in capsaicin-pretreated rats.
Topics: Animals; Animals, Newborn; Antibody Formation; Antigens; Capsaicin; Inflammation; Injections, Subcutaneous; Leukocyte Count; Lymph Nodes; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P | 1987 |
Substance P induced hydrolysis of inositol phospholipids in rat skin in an in vivo model of inflammation.
Topics: Animals; Blister; Capillary Permeability; Capsaicin; Histamine; Hydrolysis; Inflammation; Phosphatidylinositols; Pyrilamine; Rats; Skin; Substance P | 1989 |
Inhibition of carrageenan induced inflammation in the rat knee joint by substance P antagonist.
Topics: Animals; Capsaicin; Carrageenan; Hindlimb; Inflammation; Joints; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Synovitis | 1989 |
The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat.
Topics: Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Hindlimb; Immune Sera; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1989 |
Participation of substance P in inflammatory responses.
Topics: Animals; Capsaicin; Dactinomycin; Denervation; Dexamethasone; Edema; Hot Temperature; Inflammation; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Nerves; Substance P | 1989 |
Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper.
Topics: Animals; Capsaicin; Diterpenes; Female; Hypothermia; Inflammation; Pain; Rats; Rats, Inbred Strains | 1989 |
Involvement of capsaicin-sensitive afferent nerve fibres in serotonin-induced plasma extravasation and vasodilatation in rat skin.
Topics: Animals; Animals, Newborn; Capsaicin; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Serotonin; Skin; Vasodilation | 1989 |
Antidromic vasodilatation and neurogenic inflammation.
Topics: Animals; Capsaicin; Efferent Pathways; Electric Stimulation; Female; Humans; Inflammation; Male; Nerve Endings; Nociceptors; Rats; Rheology; Skin; Spinal Nerve Roots; Vasodilation | 1988 |
The effects of capsaicin denervation on leucocyte and complement components of the inflammatory response.
Topics: Animals; Capsaicin; Complement Hemolytic Activity Assay; Complement System Proteins; Female; Immune System; Inflammation; Leukocytes; Rats; Rats, Inbred Strains | 1987 |
Neurogenically mediated plasma extravasation in dura mater: effect of ergot alkaloids. A possible mechanism of action in vascular headache.
Topics: Animals; Capillary Permeability; Capsaicin; Dura Mater; Electric Stimulation; Ergot Alkaloids; Guinea Pigs; Inflammation; Nerve Fibers; Plasma; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Vascular Headaches | 1988 |
Effect of capsaicin on bronchial reactivity and inflammation in sensitized adult rats.
Topics: Animals; Antibodies; Capsaicin; Histocompatibility Antigens Class II; Immunization; Inflammation; Neuropeptides; Ovalbumin; Rats; Rats, Inbred BN; Rats, Inbred WF; Respiratory Hypersensitivity; Serotonin; Tachykinins | 1987 |
Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain.
Topics: Animals; Blood Proteins; Brain; Capsaicin; Dura Mater; Electric Stimulation; Guinea Pigs; Headache; Inflammation; Iodine Radioisotopes; Nerve Fibers, Myelinated; Rats; Rats, Inbred Strains | 1987 |
Effect of capsaicin on croton oil and TPA induced tumorigenesis and inflammation.
Topics: Animals; Capsaicin; Croton Oil; Female; Inflammation; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1986 |
The effect of nerve lesions on the inflammatory response to injury.
Topics: Animals; Blister; Capsaicin; Cell Count; Hydroxydopamines; Inflammation; Leukocytes; Oxidopamine; Peripheral Nerves; Proteins; Rats; Rats, Inbred Strains; Sympathectomy, Chemical | 1985 |
Neurogenic flare responses following topical application of capsaicin in humans.
Topics: Administration, Topical; Afferent Pathways; Aging; Capsaicin; Humans; Inflammation; Nervous System Physiological Phenomena; Nociceptors; Osmolar Concentration; Pain; Statistics as Topic | 1985 |