capsaicin and Innate Inflammatory Response

capsaicin has been researched along with Innate Inflammatory Response in 397 studies

Research

Studies (397)

TimeframeStudies, this research(%)All Research%
pre-199021 (5.29)18.7374
1990's98 (24.69)18.2507
2000's141 (35.52)29.6817
2010's100 (25.19)24.3611
2020's37 (9.32)2.80

Authors

AuthorsStudies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Aprile, S; Butron, L; Devesa, I; Fernandez-Carvajal, A; Ferrer-Montiel, A; Genazzani, AA; Gonzalez-Rodriguez, S; Griglio, A; Grosa, G; Pattarino, F; Pirali, T; Seiti, F; Serafini, M; Sorba, G; Travelli, C1
Doble, M; Manju, SL; Sinha, S1
Bang, SK; Cho, SJ; Choi, KH; Kang, SY; Ryu, Y; Seo, SY1
Cheng, N; Cheng, X; Ling, J; Liu, H; Ruan, Y; Tang, Z; Wu, F; Ye, F1
Chatthanathon, P; Leelahavanichkul, A; Panpetch, W; Saisorn, W; Sawatpanich, A; Somboonna, N; Tumwasorn, S; Visitchanakun, P1
Chen, X; Munjuluri, S; Obukhov, AG; Sooch, G; White, FA; Wilkerson, DA1
Frederick, KA; Gaetgens, J; Giuriato, G; Ives, SJ; Matias, A; Soares, EMKVK; Venturelli, M1
Lei, F; Yan, Z1
Calzetta, L; Cito, G; Pistocchini, E; Ritondo, BL; Rogliani, P; Verri, S1
Anders, B; Anders, M; Behrens, F; Fricker, L; Köhm, M; Kreuzer, M; Maier, C; Walter, C; Wolters, M; Zinn, S1
Guan, L; Li, J; Zhang, X1
Li, J; Liu, D; Ma, C; Wang, G; Zhang, Z; Zhong, X1
Chen, J; Dai, L; Gu, L; Li, Z; Liao, F; Liu, D; Liu, Y; Luo, P; Tang, H; Wang, J; Xia, F; Xu, C; Yang, F; Zhang, J; Zhang, Q; Zheng, L; Zhu, Y1
Boonthip, C; Den-Udom, T; Ketsawatsomkron, P; Laolob, T; Muta, K; Sibmooh, N; Sriwantana, T; Thongin, S; Uppakara, K; Wichai, U1
Asadzadeh Aghdaei, H; Azimirad, F; Azimirad, M; Gholami, F; Naseri, K; Noori, M; Yadegar, A; Zali, MR1
Chen, Q; Lai, K; Li, H; Liu, B; Luo, W; Peng, W; Tang, J; Yi, F; Zhan, C; Zhou, J1
Cheng, Y; Deng, Q; Fang, Z; Hu, L; Sun, D; Sun, L; Wang, C; Yang, B; Zhao, J1
Bliss, E; Mills, D; Thornton, T1
Abdalla, M; Aldosari, SM; Alshehri, B; El-Arabey, AA; Eltayeb, WA; Khan, J; Rakshit, G; Rudrapal, M1
Huang, CJ; Lee, CH; Lo, SL; Pu, CM; Su, SY; Yen, YH1
Helyes, Z; Szőke, É1
Guo, J; Song, Y; Tang, J; Tang, Z; Yang, Y; Yu, G; Zhu, C1
Koga, K; Uta, D; Yoshimura, M1
B T, P; Belenahalli Shekarappa, S; G S, PK; H Malojirao, V; Hanumanthappa, M; Kandagalla, S1
Artico, M; Giacomoni, C; Lattanzi, R; Maftei, D; Severini, C; Vellani, V1
Gerstberger, R; Leisengang, S; Murgott, J; Nürnberger, F; Ott, D; Roth, J; Rummel, C; Schmidt, M1
Bansal, Y; Bishnoi, M; Khare, P; Kondepudi, KK; Kuhad, A; Medhi, B; Singh, R; Sodhi, RK1
Cabeça, LF; Costa, JSR; Couto, VM; Franco, MKKD; Franz-Montan, M; Geraldes, DC; Oliveira-Nascimento, L; Paula, E; Riske, KA; Yokaychiya, F1
Aguilera-Lizarraga, J; Alpizar, YA; Berg, M; Boeckxstaens, G; De Man, JG; De Winter, B; Florens, MV; Hanning, N; Jain, P; Perna, E; Talavera, K; Theofanous, SA; Vanden Berghe, P; Wouters, M1
Koch, M; Messlinger, K; Sertel-Nakajima, J1
Iesanu, MI; Paslaru, AC; Rosca, AE; Voiculescu, SE; Zagrean, AM; Zahiu, CDM1
Bach, H; Carranza, A; Gorzalczany, SB; Rodríguez Basso, A; Zainutti, VM1
Ali, M; Basharat, A; Basharat, S; Gilani, SA; Iftikhar, F; Murtaza, MA; Qamar, MM; Sattar, A1
Ballester, GF; Butron, L; Devesa, I; Fernández-Carvajal, A; Ferrer-Montiel, A; Genazzani, AA; González-Rodríguez, S; Nikolaeva-Koleva, M; Pirali, T; Serafini, M; Valente, P1
Alhouayek, M; Ben Kouidar, Y; Buisseret, B; Guillemot-Legris, O; Muccioli, GG; Paquot, A1
Belboukhari, N; Cheriti, A; Ould El Hadj-Khelil, A; Seddiki, LS; Sekkoum, K; Sulaiman, MR1
Ballegaard, AR; Bøgh, KL; Larsen, JM; Pilegaard, K; Rasmussen, PH; Untersmayr, E1
Abd Al Haleem, EN; Arafa, HMM; Hasan, WYS1
An, N; Gao, Q; Li, J; Ni, W; Wang, H; Yu, Y; Zhang, L1
Aguilera, M; Cryan, JF; Fanning, A; Felice, VD; Grady, F; Hickey, A; McCarthy, L; Melgar, S; Moloney, A; Nally, K; O'Mahony, SM; Pawley, L; Rossini, V; Shanahan, F; Simnica, D1
Arulsamy, N; Baskaran, M; Baskaran, P; Thyagarajan, B1
Chen, M; Huang, L; Hui, S; Kaliannan, K; Kang, C; Lang, H; Mi, M; Wang, B; Wang, X; Zhang, Y; Zhou, M1
Cull-Candy, SG; Farrant, M; Sullivan, SJ1
Caruntu, C; Constantin, C; Georgescu, SR; Ilie, MA; Matei, C; Neagu, M; Sârbu, MI; Tampa, M1
Jones, KS; Truong, T1
Atmaramani, R; Black, BJ; Campbell, ZT; Dussor, G; Kumaraju, R; Pancrazio, JJ; Plagens, S; Price, TJ; Romero-Ortega, M1
Gu, Y; Huang, LM; Li, G1
Ma, S; Wang, DH; Yu, SQ1
Callejo, G; Chakrabarti, S; Hockley, JRF; Pattison, LA; Singhal, K; Smith, ESJ1
Barik, A; Bharucha-Goebel, D; Bönnemann, CG; Bushnell, MC; Case, L; Chesler, AT; Donkervoort, S; Foley, AR; Ghitani, N; Gordon, T; Lam, R; Liljencrantz, J; Necaise, A; Saade, D; Szczot, M; Thompson, JH1
Abdelaziz, R; Barry, AM; Gomez-Varela, D; Jahn, O; Kügler, S; Michel, N; Schmidt, M; Sondermann, JR1
Baudouin, C; Ben-Dhaou, C; Melik Parsadaniantz, S; Ouimet, T; Poras, H; Reaux-Le Goazigo, A; Wurm, M1
Adamante, G; Bellinaso, F; Camponogara, C; Casoti, R; Coelho, YO; da Silva Silveira, E; de Almeida, AS; De Prá, SD; Desideri, AV; Ferreira, J; Milioli, AM; Oliveira, SM; Rigo, FK; Santos, MFC; Trevisan, G1
Aghajani, M; Amani, A; Esmaeli, F; Faramarzi, MA; Ghazi-Khansari, M; Ghiasi, Z1
Duan, W; Fang, Y; Ma, C; Xie, Y; Zhu, J1
Bjerrum, OJ; Dalbøge, LS; Dupont, E; Heegaard, AM; Jensen, TS; Larsen, M; Møller, AT; Møller, LB; Nasser, A1
Buelow, DR; Konkel, ME; Neal-McKinney, JM; Riley, TP; Simasko, SM1
Baeyens, JM; Cobos, EJ; Entrena, JM; García-Granados, A; Nieto, FR; Parra, A1
Chen, HS; Li, FP; Li, XQ; Lin, Q; Liu, BJ; Qu, F; Wang, Y; Wen, WW1
Borghi, SM; Carvalho, TT; Casagrande, R; Hohmann, MS; Pinge-Filho, P; Staurengo-Ferrari, L; Verri, WA1
Dolan, S; Goldie, M1
Córdova, MM; Montrucchio, DP; Santos, AR1
Ching, LC; Kou, YR; Lee, TS; Lin, SJ; Shyue, SK; Wei, J; Zhao, JF1
Bhatnagar, A; Billeter, AT; Hellmann, JL; Polk, HC1
Dvorakovskaya, IV; Fedin, AN; Kuzubova, NA; Lebedeva, ES; Titova, ON1
Jolayemi, AT; Ojewole, JA1
Alhelal, MA; Letourneau, R; Palaska, I; Panagiotidou, S; Theoharides, TC1
Andreev, YA; Bondarenko, DA; Dyachenko, IA; Grishin, EV; Kabanova, NV; Kolesnikov, SS; Korolkova, YV; Kotova, PD; Kozlov, SA; Murashev, AN; Rogachevskaja, OA; Skobtsov, DI1
Almeida, FR; Amaral, MP; Chaves, MH; Costa, DA; Figueiredo, KA; Júnior, FB; Oliveira, FA; Oliveira, IS; Oliveira, RC; Silva, FV1
Dickie, AC; Torsney, C1
Doods, H; Gorham, L; Just, S1
Amaral, LS; Barreiro, EJ; Fraga, CA; Guimaraes, MZ; Lacerda, RB; Lima, CK; Miranda, AL; Quintas, LE; Santos, BL; Silva, RM; Silva, RV1
Fürst, R; Zündorf, I1
Abramson, L; Aoki-Nonaka, Y; Bertin, S; Corr, M; de Jong, PR; Dong, H; Franco, A; Fu, G; González-Navajas, JM; Gwack, Y; Han, T; Herdman, S; Jefferies, WA; Lee, J; Li, X; Nohara, LL; Raz, E; Srikanth, S; Stanwood, SR; To, K; Touma, R; Xu, H; Yu, T1
Basrur, V; Gowda, LR; Joe, B; Lokesh, BR; Nagaraju, A1
Kress, M; Langeslag, M; Leitner, MG; Mair, N; Quarta, S1
Albers, KM; Gold, MS; Zhang, XL1
Guindon, J; Lin, JS1
Boakye, CH; Godugu, C; Mendonca Faria, HA; Patel, AR; Singh, M; Somagoni, J; Zucolotto, V1
Kumamoto, N; Shibata, Y; Ueda, T; Ugawa, S; Watanabe, M1
Matoba, M; Minami, K; Miyano, K; Murakami, S; Ohbuchi, K; Shiraishi, S; Uezono, Y; Yamaguchi, T; Yamamoto, M; Yokoyama, T1
Binkowski, M; Czaja, M; Di Marzo, V; Kolosowska, N; Makuch, W; Malek, N; Morera, E; Mrugala, M; Przewlocka, B; Starowicz, K1
Bertin, S; Raz, E1
Cai, J; Kong, JG; Liao, FF; Liu, FY; Wan, Y; Xiao, X; Xing, GG; Xu, LC; Yi, M; Yue, LP; Zhao, XT1
Chen, C; Fan, F; Lin, C; Liu, Y; Liu, Z; Lu, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zhao, L; Zhu, P; Zhu, Z1
Bogdanov, Y; Crow, M; Denk, F; Grant, AD; Kelleher, JH; Khovanov, N; McMahon, SB; Sharma, S; Wood, JN1
Gan, YH; Hao, T; Kou, XX; Ma, XC; Wu, YW1
He, LL; Jiao, HY; Li, PB; Liao, Y; Su, WW; Zhou, Q; Zhu, N1
Jiang, Y; Lai, R; Lv, HN; Sun, XY; Wang, K; Wei, NN; Wu, Y; Yang, SL1
Belmonte, C; de la Peña, E; Ferrer-Montiel, A; Gomis, A1
Davletov, B; Ferrari, E; Geranton, SM; Hunt, SP; Leese, C; Maiarú, M; Mangione, AS; Obara, I; Tassorelli, C1
Bradshaw, H; Carey, LM; Cornett, B; Hohmann, AG; Leishman, E; Mackie, K; Slivicki, RA1
Gao, JJ; Guo, FX; Hu, YW; Huang, C; Kang, CM; Li, P; Lu, JB; Ma, X; Qiu, YR; Sha, YH; Wang, Q; Wang, YC; Xiu, JC; Xu, BM; Zhang, Y; Zhao, JJ; Zheng, L1
Kaur, CD; Mazumder, B; Sarwa, KK; Suresh, PK1
Frias, B; Merighi, A1
Kim, JM; Park, K; Shin, YH1
Babes, A; Becker, C; Engel, MA; Khalil, M; Kistner, K; Neurath, MF; Reeh, PW; Selescu, T; Siklosi, N; Wirtz, S; Zimmermann, K1
Finn, DP; Lenihan, R; Madasu, MK; Okine, BN; Olango, WM; Rea, K; Roche, M1
Aboushousha, R; Altier, C; Basso, L; Flynn, R; Iftinca, M; Melo, H; Taylor, L1
Coderre, TJ; Ding, S; Gyawali, S; Laferrière, A; Mahboubi, H; Mickeviciute, A; Nasir, H; Ragavendran, JV; Stochaj, U1
Berta, T; Bey, AL; Chang, W; Han, Q; Ji, RR; Jiang, YH; Kim, YH; Lay, M; Liu, D; Wang, X; Zhang, Y; Zhang, ZJ1
Andersen, HH; Arendt-Nielsen, L; Elberling, J1
Amuzescu, B; Caruntu, C; Deftu, A; Filippi, A; Gheorghe, RO; Ristoiu, V1
Gu, Q; Qu, C; Xu, Y1
Chen, Y; Han, JS; Li, GX; Li, T; Liu, FY; Luo, H; Shi, YS; Wan, Y; Xing, GG; Xu, IS; Yang, F; Yu, L1
Eijkelkamp, N; Elsenbruch, S; Heijnen, CJ; Holtmann, G; Kavelaars, A; Schedlowski, M1
Ballard, A; Bishop, T; Holmes, H; McMahon, SB; Young, AR1
Fang, L; Li, D; Lin, Q; Wang, P; Xu, X; Zou, X1
Brookes, SJ; Chen, BN; Costa, M; Lynn, PA; Zagorodnyuk, VP1
Arpino, S; Biggs, J; Coleman, T; Cryan, JE; Davis, JB; Gunthorpe, MJ; Holland, V; Jerman, JC; Lappin, SC; Medhurst, SJ; Mitchell, DJ; Rami, HK; Seal, JT; Stemp, G; Stevens, AJ; Thompson, M; Trouw, LS; Westaway, SM; Winborn, KY; Wright, J1
Huang, J; Wang, W1
García-López, BE; Granados-Soto, V; Herrejon-Abreu, EB; López-Santillán, FJ; Murbartián, J; Rocha-González, HI1
Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Vale, ML1
Cheng, TL; Hsu, KS; Huang, HT; Lam, HC; Lin, CJ; Liu, GS; Liu, LF; Shi, JY; Tai, MH; Tseng, RT; Wen, ZH; Weng, WT1
Adler, JE; Skoff, AM; Zhao, C1
Kang, JH; Kim, CS; Yu, R1
Bortolatto, CF; Jesse, CR; Nogueira, CW; Savegnago, L; Wilhelm, EA1
Goto, T; Han, IS; Kang, JH; Kawada, T; Kim, YM; Yu, R1
Verkman, AS; Zhang, H1
Fang, L; Gong, K; Li, D; Lin, Q; Wang, P; Xu, X; Zou, X1
Jeon, MS; Kim, BD; Kim, JH; Kim, TY; Kwon, YG; Lee, EJ; Lee, H; Lee, YS; Yang, JH1
Bettoni, I; Comelli, F; Costa, B; Di Marzo, V; Giagnoni, G; Petrosino, S1
Bakthavatchalam, R; Blum, CA; Boyce, S; Brielmann, H; Burnaby-Davies, N; Caldwell, T; Capitosti, S; Chenard, BL; Conley, R; Cortright, D; Crandall, M; De Lombaert, S; Hodgetts, KJ; Jones, AB; Kershaw, MT; Krause, JE; Martin, WJ; Mason, G; Matson, D; Murphy, BA; Perrett, H; Rycroft, W; Zheng, X1
Coderre, TJ; Kumar, N; Laferriere, A; Poon, T; Yu, JS1
Buurman, WA; de Haan, JJ; Dejong, CH; Greve, JW; Hadfoune, M; Lubbers, T; Luyer, MD; Verbaeys, I1
Al-Khrasani, M; Brendl, U; Fürst, S; Mousa, SA; Schäfer, M; Shaqura, M1
Bunch, J; Jajoo, S; Kaur, T; Mukherjea, D; Perro, C; Ramkumar, V; Rybak, LP; Sheehan, K; Sheth, S1
Bai, ZT; Cheng, M; Hua, LM; Ji, YH; Jiang, F; Liu, T; Pang, XY; Shi, J; Shu, XQ; Zhang, JW; Zhou, JJ1
Drummond, PD; Knudsen, L1
Hayes, D; Lee, LY; Lin, RL; Ni, D1
Andrade, EL; Calixto, JB; Rogerio, AP1
Benoit, M; Chen, X; Gudermann, T; Hofmann, T; Janssens, A; Kerselaers, S; Nilius, B; Oberwinkler, J; Owsianik, G; Philipp, SE; Stab, J; Vennekens, R; Voets, T; Vriens, J; Xue, F1
Bang, S; Cho, H; Hwang, SW; Yang, TJ; Yoo, S1
Ji, W; Liang, J; Xiao, G1
Holstege, JC; Hossaini, M; Jongen, JL; Saraç, C1
Barbosa, S; Fernández-Blanco, JA; Martínez, V; Sánchez de Medina, F; Vergara, P1
Ang, SF; Bhatia, M; MacAry, PA; Moochhala, SM1
Deering-Rice, CE; Dull, RO; Lee, J; Reilly, CA; Roberts, JK; Romero, EG; Thomas, KC; Yost, GS1
Canetta, SE; Luca, E; Pertot, E; Role, LW; Talmage, DA1
Daugherty, D; Dykstra, LA; Henry, FE; Miller, LL; Picker, MJ1
Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M1
Henry, PJ; Mann, TS; Taylor, SJ1
Jia, MM; Li, XJ; Li, YS; Liu, M; Tang, HB; Wang, JX1
Endo, T; Inagaki, N; Nagai, H; Saito, A; Shimouchi, A; Tanaka, H; Tominaga, M; Usuda, H; Yamashita, H1
Honda, K; Iwata, K; Okada-Ogawa, A; Shinoda, M1
Dolan, S; Graham, A; Iannitti, T1
Comelli, F; Costa, B; D'Agostino, B; de Novellis, V; De Petrocellis, L; Di Marzo, V; Gatta, L; Guida, F; Luongo, L; Maione, S; Matteis, M; Sullo, N1
Fereidoni, M; Niazmand, S; Sepehri, Z1
Honda, K; Iwata, K; Katagiri, A; Matsuura, S; Ogiso, B; Ohara, K; Sessle, BJ; Shimizu, K; Shinoda, M; Urata, K1
Casey, KL; Cross, DJ; Lorenz, J; Minoshima, S; Morrow, TJ; Paulson, PE1
Cai, Y; Evensjö, M; Kovács, KJ; Larson, AA; McCarson, KE; Shi, Q; Velázquez, RA1
Braun, A; Hoyle, GW; Kerzel, S; Meents, N; Nockher, WA; Päth, G; Quarcoo, D; Raap, U; Renz, H1
Fox, AJ; McIntyre, P; Medhurst, SJ; Panesar, M; Patel, S; Urban, L; Walker, KM1
Carr, MJ; Undem, BJ1
Bayer, MK; Chavolla-Calderón, M; Fontán, JJ1
Li, GD; Zhao, ZQ; Zhou, Y1
Bristol, DR; Harrison, JE; Mark, L; Pomonis, JD; Valenzano, KJ; Walker, K1
Carr, BA; Crouch, DJ; Lanza, DL; Reilly, CA; Taylor, JL; Yost, GS1
Hamamoto, DT; Hodges, JS; Maccecchini, ML; Simone, DA; Turner, MS1
Gábor, M1
Al-Chaer, ED; Kawasaki, M1
Davies, C; Harrison, NK; Hilldrup, S; Hope-Gill, BD; Newton, RP1
Gustafsson, H; Hole, K; Kjørsvik Bertelsen, A; Stiller, CO; Tjølsen, A; Warsame Afrah, A1
Fang, L; Lin, Q; Willis, WD; Wu, J2
Bueno, L; Bunnett, NW; Cenac, N; Coelho, AM; Compton, SJ; Garcia-Villar, R; Grady, E; Hollenberg, MD; Nguyen, C; Steinhoff, M; Vergnolle, N; Wallace, JL1
Boyle, DL; Firestein, GS; Moore, J; Sorkin, LS; Yang, L1
Green, PG; Levine, JD; Miao, FJ1
Fang, L; Lin, Q; Ren, Y; Wang, J; Willis, WD; Zou, X1
Bánvölgyi, A; Brain, SD; Ghosh, M; Helyes, ZS; Melegh, B; Pintér, E; Pozsgai, G; Szolcsányi, J1
Baamonde, A; Hidalgo, A; Lastra, A; Menéndez, L1
Cortright, DN; Szallasi, A1
Baamonde, A; Fresno, MF; Hidalgo, A; Lastra, A; Llames, S; Meana, A; Menéndez, L1
Drummond, PD1
Carlton, SM; Castañeda-Hernandez, G; Du, J; Grady, JJ; Jimenez-Andrade, JM; Yamani, A; Zhou, S1
Colleoni, M; Costa, B; Franke, C; Giagnoni, G; Trovato, AE1
Clapham, DE; Ji, RR; Xu, H; Zhuang, ZY1
Higashi, T; Iida, T; Moriyama, T; Murayama, N; Numazaki, M; Togashi, K; Tominaga, M; Tominaga, T1
Jones, CK; Peters, SC; Shannon, HE1
Bayraktar, M; Bayraktar, N; Demirbilek, S; Ersoy, MO; Gürbüz, N; Karaman, A1
Bonebreak, DB; Flake, NM; Gold, MS1
Arata, V; Kasahara, DI; Leick-Maldonado, EA; Martins, MA; Prado, CM; Tibério, IF1
Bannon, AW; Doherty, EM; Gavva, NR; Immke, D; Klionsky, L; Louis, JC; Norman, MH; Porreca, F; Qu, Y; Tamir, R; Treanor, JJ; Vanderah, TW; Wang, J; Wild, KD; Zhang, TJ; Zhu, D1
Ko, S; Qiu, CS; Toyoda, H; Zhao, MG; Zhuo, M1
Tominaga, M1
Caterina, M; Cowan, A; Inan, S; Oppenheim, JJ; Rogers, TJ; Sun, R; Wang, JM; Zhang, N1
Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S1
Amadesi, S; Dinh, QT; Fischer, A; Geppetti, P; Groneberg, DA; Harrison, S; Lencer, D; Maggiore, B; Peiser, C; Trevisani, M1
Breese, NM; George, AC; Pauers, LE; Stucky, CL1
El Kouhen, R; Faltynek, CR; Gauvin, DM; Gomtsyan, A; Honore, P; Jarvis, MF; Lee, CH; Marsh, K; Mikusa, J; Sullivan, JP; Wismer, CT; Zhong, C; Zhu, CZ1
Carini, F; Messina, P; Scardina, GA1
Breuer, A; Fride, E; Hanus, L; Ponde, D1
Cairns, BE; Hu, JW; Lam, DK; Sessle, BJ1
Camerer, E; Coughlin, SR; Hamilton, JR; Matthay, MA; Su, X1
Carlton, SM; Castañeda-Hernandez, G; Jimenez-Andrade, JM; Valencia de Ita, S; Yamani, A; Zhou, S1
Ahern, GP; O'Connell, PJ; Pingle, SC1
Compte, L; De Diego, A; Macián, V; Martínez, E; Nieto, L; Perpiñá, M; Senent, L1
Brozmanova, M; Hutka, Z; Pecova, R; Petriskova, J; Raffajova, J; Tatar, M; Zucha, J1
Kostina, NE; Spiridonov, VK2
Baamonde, A; Hidalgo, A; Juarez, L; Lastra, A; Menéndez, L1
Baamonde, A; García, E; García-Suárez, O; Hidalgo, A; Juárez, L; Menéndez, L1
Abbadi, N; Ase, A; Breese, NM; Mogil, JS; Rainville, ML; Ritchie, J; Séguéla, P; Stucky, CL; Witty, MF1
Brain, SD; Costa, SK; Muscará, MN; Poston, RN; Yshii, LM1
Hohmann, AG; Nackley, AG; Neely, MH; Piña, J1
Fu, Y; Kochukov, MY; McNearney, TA; Westlund, KN1
Beitz, AJ; Choi, SM; Han, HJ; Kang, SY; Kim, HW; Kim, KW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Ryu, YH; Yoon, SY1
Arendt-Nielsen, L; Chen, HS; Graven-Nielsen, T; He, X; Lei, J; Wang, Y; Wei, XZ; Wen, WW; You, HJ1
Amadesi, S; Andre, E; Bunnett, NW; Dinh, TQ; Fischer, A; Gatti, R; Geppetti, P; Harrison, S; Trevisani, M1
Carlton, SM; Ji, GC; Jurczyk, S; Reubi, JC; Shapiro, G; Zhou, ST1
Castañeda-Hernandez, G; Lawand, NB; Lin, Q; Valencia-de Ita, S; Willis, WD1
Chang, SY; Ho, CY; Kou, YR; Tsai, TL1
Cabot, PJ; Hermanussen, S; Kapitzke, D; Monteith, GR; Vetter, I1
Fujimura, M; Liu, Q1
Harada, N; Okajima, K1
Manjunatha, H; Srinivasan, K1
Amaya, F; Barrett, L; Lin, CR; Samad, TA; Takada, J; Wang, H; Woolf, CJ1
Belmonte, C; Carreño, C; Fernández-Carvajal, A; Ferrer-Montiel, A; Ferroni, S; García-Martínez, C; Gomis, A; Valenzuela, B; Van Den Nest, W1
Chabot, JG; Ma, W; Quirion, R1
Amadesi, S; Bunnett, N; Hu, WP; Li, JD; Luo, ZD; Zhang, C; Zhou, QY1
Bolser, DC; Brown, D; Chen, J; Fernandez, X; Hey, JA; Jia, Y; Kreutner, W; McHugh, NA; McLeod, RL; Mingo, GG; Parra, LE; Wang, X1
Colleoni, M; Comelli, F; Costa, B; Giagnoni, G; Trovato, AE1
Afifiyan, FN; Chan, Y; Dosch, HM; Driver, JP; Liu, XJ; Razavi, R; Salter, MW; Santamaria, P; Serreze, D; Tang, L; Tsai, S; Tsui, H; Wan, X; Yantha, J1
Barrett, AC; Lomas, LM; Lysle, DT; Picker, MJ; Terner, JM1
Börzsei, R; Elekes, K; Helyes, Z; Kereskai, L; Németh, J; Pintér, E; Pozsgai, G; Sándor, K; Szabó, A; Szolcsányi, J1
Bianchi, R; Borsani, E; Labanca, M; Rodella, LF1
Brandt, MR; Colburn, RW; D'Andrea, MR; Flores, CM; Lawrence, D; Liu, Y; Lubin, ML; Qin, N; Stone, DJ; Wang, Y1
Atkinson, R; Carroll, W; Chapman, M; Chu, K; Drizin, I; Faltynek, CR; Gauvin, D; Gregg, R; Gross, M; Hakeem, A; Hernandez, G; Honore, P; Jarvis, MF; Johnson, M; Joshi, S; Kort, M; Krafte, DS; Krambis, M; Liu, D; Liu, Y; Marron, B; Marsh, K; Matulenko, M; McGaraughty, S; Mikusa, JP; Pai, M; Roeloffs, R; Scanio, M; Shi, L; Shieh, CC; Sullivan, JP; Thomas, J; Wade, C; Wagoner, PK; Zhang, XF; Zhong, C; Zhu, C1
Gyires, K; Helyes, Z; László, J; Sándor, K; Szolcsányi, J1
Amadesi, S; Bunnett, NW; Chapman, K; Cottrell, GS; Gedda, K; Hollenberg, MD; Knecht, W; Mohlin, J; Peterson, A; Skåregärde, A; Vergnolle, N1
Bagoly, T; Börzsei, R; Elekes, K; Helyes, Z; Márk, L; Németh, J; Pintér, E; Pozsgai, G; Reglodi, D; Szolcsányi, J; Tóth, G1
Brain, SD; Kofler, B; Schmidhuber, SM; Starr, A; Wynick, D1
Fujimura, M; Hara, J; Kasahara, K; Kita, T; Myou, S; Ohkura, N; Oribe, Y; Ueda, A; Yasui, M1
Abu-Asab, M; Iadarola, MJ; Jenkins, AC; Karai, LJ; Mannes, AJ; Neubert, JK; Zawatski, L1
Ahmadi, S; Brockhaus, J; Brune, K; Fritschy, JM; Hess, A; Hösl, K; Knabl, J; Möhler, H; Reinold, H; Rudolph, U; Sergejeva, M; Witschi, R; Zeilhofer, HU; Zeilhofer, UB1
Brand, A; Erdmann, B; Heppenstall, PA; Hu, J; Jüttner, R; Laurito, CE; Lewin, GR; Lu, Y; Milenkovic, N; Park, TJ; Smith, ES; Wetzel, C; Wilson, SP1
Hernández, E; Rudomin, P1
Grau, JW; Hook, MA; Huie, JR1
Gold, MS; Lu, SG1
Alves, MK; Carvalho, TA; Cunha, FQ; de Oliveira, JR; Leite, CE; Lunardelli, A; Poloni, JA; Spiller, F; Vieira, SM1
Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y1
Anggård, A; Lundberg, JM; Lundblad, L; Martling, CR1
Colpaert, FC; Donnerer, J; Lembeck, F1
Jancśo, G; Jancsó-Gábor, A; Király, E1
Cruwys, SC; Garrett, NE; Kidd, BL1
Cambridge, H1
Bennett, DL; McMahon, SB; Priestley, JV; Shelton, DL1
Bartoshuk, L; Berger, A; Cooper, D; Duffy, V; Henderson, M; Nadoolman, W; Saberski, L1
Blanchard, JC; Carruette, A; Garret, C; Laduron, PM; Montier, F; Moussaoui, SM1
Desai, MC; Hoffman, JI; Husseini, WK; Nadel, JA; Piedimonte, G; Snider, RM1
Garret, C; Le Prado, N; Moussaoui, SM; Philippe, L1
Handwerker, HO; Ringkamp, M; Schmelz, M; Schmidt, R; Torebjörk, HE1
Dubner, R; Ren, K; Ruda, MA; Williams, GM1
Castro-Lopes, JM; Coimbra, A; Tavares, I; Tölle, TR1
Amico-Roxas, M; Caruso, A; Catena Cutuli, VM; Clementi, G; de Bernardis, E; Maugeri, S; Prato, A; Scapagnini, U1
Boyer, V; D'Ortho, MP; Harf, A; Jarreau, PH; Macquin-Mavier, I1
Dow, RC; Fink, G; Hopkins, SJ; Rothwell, NJ; Turnbull, AV; White, A1
Frevert, CW; Long, NC; Shore, SA2
Bertrand, C; Foresi, A; Geppetti, P; Graf, PD; Nadel, JA1
Arbetter, K; Leff, AR; Mitchell, RW; Ndukwu, IM; Solway, J1
Berman, EF; Buckwalter, BL; Farmer, RW; Janusz, JM; Kasting, GB; Kerckaert, GA; LaHann, TR; Loomans, ME; Maddin, CS; Young, PA1
Everaert, E; Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA1
Spiridonov, VK; Zhukova, EM1
Philip, G; Sanico, AM; Togias, A1
Baluk, P; Bowden, JJ; Lefevre, PM; Lindsey, JR; McDonald, DM; Schoeb, TR1
Blake, DR; Brain, SD; Cambridge, H; Kerslake, S; Mapp, PI1
Ceserani, R; Dalla Rosa, C; Gallico, L; Oggioni, N; Tognella, S1
Hu-Tsai, M; Winter, J; Woolf, C1
Lynn, B; Pierau, FK; Schütterle, S1
Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH1
Alm, P; Håkanson, R; Wang, ZY1
Baluk, P; Bowden, JJ; Bunnett, NW; McDonald, DM1
Baudoin, T; Ferencic, Z; Kalogjera, L; Pegan, B; Ries, M; Trotic, R1
Boucher, RC; Costa, DL; Lehmann, JR; McCarty, D; Pickles, RJ; Piedimonte, G1
Dimitriadou, V; Garbarg, M; Luffau, G; Miller, HR; Newlands, GJ; Rouleau, A; Schwartz, JC; Trung Tuong, MD1
Grundemar, L; Håkanson, R; Waldeck, K; Wang, ZY1
do Patrocínio, M; Lapa e Silva, JR; Leick-Maldonado, EA; Martins, MA; Paiva, SO; Sakae, RS; Saldiva, PH; Tibério, IF; Turco, GM; Warth, TN1
Canning, BJ1
Averbeck, B; Bickel, A; Luz, O; Schmelz, M1
Desouza, IA; Ribeiro-DaSilva, G1
Aubineau, P; Delépine, L1
Knotková-Urbancová, H; Kress, M; Reeh, PW; Vitásková, Z; Vlachová, V; Vyklický, L1
Didier, A; Igarashi, Y; Kaliner, MA; Kowalski, ML; Lundgren, JD1
Bullock, B; Dickerson, C; Undem, B; Winchurch, RA1
Elde, R; Schäffer, M; Stein, C; Zhang, Q1
De Freitas, GA; Santos, AR; Vedana, EM1
Dong, F; Hasegawa, S; Iijima, H; Nomura, A; Uchida, Y; Xiang, A; Zhang, MJ1
Helyes, Z; Németh, J; Oroszi, G; Pintér, E; Szolcsányi, J1
Hwang, SW; Jung, JY; Kwak, JY; Lee, WT; Oh, U1
Ansel, JC; Armstrong, CA; Bunnett, NW; Caughman, SW; Letran, EL; Naik, SM; Olerud, JE; Quinlan, KL; Song, IS1
Pierau, FK; Sann, H1
Hamilton, SG; McMahon, SB; Wade, A1
Abe, T; Arisaka, O; Oyama, M; Watanabe, M; Yoshihara, S1
Damas, J; Liégeois, JF1
Ebersberger, A; Messlinger, K; Oppmann, M; Pawlak, M; Schepelmann, K1
Dirig, DM; Yaksh, TL1
Chiang, YC; Hu, JW; Sessle, JB; Sunakawa, M1
Bergmann, R; Nicholas, RS; Winter, J; Woolf, CJ; Wren, P1
Cesare, P; McNaughton, PA; Moriondo, A; Vellani, V1
Abraham, J; Kobzik, L; Krishna Murthy, GG; Long, NC; Shore, SA; Weller, EA1
Lin, Q; Willis, WD; Wu, J1
Basbaum, AI; Caterina, MJ; Julius, D; Koltzenburg, M; Leffler, A; Malmberg, AB; Martin, WJ; Petersen-Zeitz, KR; Trafton, J1
Distler, C; Habelt, C; Kessler, F; Kress, M; Reeh, PW1
Atkinson, K; Bingham, S; Clapham, C; Davey, PT; Davis, JB; Grau, E; Gray, J; Gunthorpe, MJ; Harper, AJ; Harries, MH; Hatcher, JP; Hughes, SA; Latcham, J; Overend, P; Pugh, PL; Rance, K; Randall, A; Rogers, DC; Sheardown, SA1
Cho, H; Cho, S; Hwang, SW; Jung, J; Kang, CJ; Kim, D; Kwak, J; Lee, SY; Min, KH; Oh, U; Suh, YG1
Cascante, M; Creppy, EE; Ennamany, R; Richeux, F; Saboureau, D; Sanchez, D; Sanni, A1
Southall, MD; Vasko, MR1
Cervero, F; De Felipe, C; Hunt, SP; Laird, JM; Olivar, T; Roza, C1
Regoli, D1
Ito, T; Kawai, Y; Tamura, T; Yonehara, N; Yoshimura, M1
Helyes, Z; Németh, J; Pintér, E; Szilvássy, Z; Szolcsányi, J; Thán, M1
Adelson, DW; Kruger, L; Maidment, NT; Matsuka, Y; Neubert, JK; Spigelman, I1
Belmonte, C; Gallar, J; Pozo, MA; Rivera, L1
Janig, W; Levine, JD; Miao, FJ1
Choi, SY; Ha, H; Kim, KT1
Cirillo, R; Evangelista, S; Lippi, A; Maggi, CA; Manzini, S; Terracciano, R; Vieira, C1
Lacroix, JS; Malis, DD1
Blakeman, KH; Ernfors, P; Hao, JX; Hassani, H; Lucas, G; Naveilhan, P; Thorén, P; Wiesenfeld-Hallin, Z; Xu, XJ1
Bueno, L; Fioramonti, J; Garcia-Villar, R; Gay, J1
Itoh, M; Konemura, T; Kuraishi, Y; Sasaki, M; Sasamura, T; Tohda, C1
Fujimura, M; Kasahara, K; Liu, Q; Myou, S; Tachibana, H; Yasui, M1
Changeux, JP; Damaj, MI; Epping-Jordan, MP; Marubio, LM; Merlo-Pich, E; Salmon, AM1
Benowitz, NL; Levine, JD; Miao, FJ1
Bonaria Salis, M; Carta, L; Deiana, M; Emanueli, C; Franca Milia, A; Gaspa, L; Madeddu, P; Pinna, A; Stacca, T1
Gourine, AV; Kluger, MJ; Korsak, AS; Kozak, W; Kubatko, J; Rudolph, K; Tesfaigzi, J1
Gillard, SE; Hammond, DL; Hurley, RW; Miller, RJ; Oh, SB; Tran, PB1
Averbeck, B; Cirillo, R; Evangelista, S; Fetzer, S; Kress, M; Lippi, A; Maggi, CA; Manzini, S; Reeh, PW; Sauer, SK; Vieira, C1
Lin, Q; Willis, WD; Zou, X1
Kasai, M; Mizumura, K1
Amuzescu, B; Babes, A; Flonta, ML; Krause, U; Reid, G; Scholz, A1
Belmonte, C; Caprini, M; Carbonell, T; De Felipe, C; De La Pena, E; Ferrer-Montiel, A; García-Martinez, C; Gomis, A; Humet, M; Messeguer, A; Pérez-Paya, E; Planells-Cases, R; Sanchez-Baeza, F; Viana, F1
Chidiac, JJ; Hawwa, NN; Jabbur, SJ; Jurjus, AR; Massaad, CA; Rifai, K; Saadé, NE1
Carini, F; Catalioto, RM; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P; Tramontana, M1
Eysselein, VE; Gerken, G; Goebell, H; Hoffmann, P; Holtmann, G; Mazurkiewicz, J1
Chapman, V; Kelly, S1
Herbert, MK; Holzer, P1
Sluka, KA1
Kiernan, JA1
Fazekas, A; Györfi, A; Rosivall, L1
Green, PG; Levine, JD1
Dimaline, R; Dockray, GJ; Forster, ER; Louis, SM; Sandvik, AK1
Håkanson, R; Wallengren, J1
Hylden, JL; Noguchi, K; Ruda, MA1
Baluk, P; McDonald, DM; Nadel, JA1
Donnerer, J; Stein, C1
Garry, MG; Hargreaves, KM1
Helme, RD; Khalil, Z4
McDonald, DM1
Brain, SD; Buckley, TL; Jose, PJ; Williams, TJ1
Davis, W; Eysselein, VE; Nast, C; Patel, A; Reinshagen, M; Sternini, C1
Abelli, L; Del Bianco, E; Drapeau, G; Giachetti, A; Maggi, CA; Regoli, D; Rovero, P1
Cooper, AL; Rothwell, NJ1
Mantione, CR; Rodriguez, R1
McDonald, DM; Nadel, JA; Umeno, E2
Balu, A; De Sanctis, GT; Fick, G; Green, F; Lopez, A; Prior, M1
De, AK; Ghosh, JJ1
Glinska-Ferenz, M; Glinski, W; Pierozynska-Dubowska, M1
Abelli, L; Conte, B; Geppetti, P; Maggi, CA; Parlani, M; Somma, V1
Brodda-Jansen, G; Hedqvist, P; Lundeberg, T; Raud, J; Theodorsson, E1
Fujita, H; Kawabata, S; Kuraishi, Y; Matsumoto, T; Nakamura, A; Satoh, M1
Ferrell, WR; Lam, FY2
Bevan, S; Dray, A; Rang, HP1
Andersson, SE; Le Greves, P1
Buzzi, MG; Dimitriadou, V; Moskowitz, MA; Theoharides, TC1
Dickenson, A; Dray, A1
Chung, ES; Cuénoud, HF; Leeman, SE1
Gebhart, GF; Ness, TJ; Randich, A1
Otten, U; Vedder, H1
Lindsey, JR; McDonald, DM; Schoeb, TR1
Barthó, L; Herz, A; Stein, C1
Basbaum, AI; Coderre, TJ; Finkbeiner, WE; Levine, JD; White, DM1
Bohne, RL; Brand, LM; Fanelli, R; Lade, DA; Loomans, ME; Maddin, CS; Moorehead, DP; Reller, HH; Schwen, RJ; Skare, KL1
Didier, A; Jay, J; Kaliner, MA; Kowalski, ML1
Kumazawa, T1
Abelli, L; Furio, M; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Somma, V1
Foreman, JC2
Andrews, PV; Boyd, RL; Dandie, GW; Eglezos, A; Helme, RD1
Andrews, PV; Helme, RD; Khalil, Z; Thomas, KL1
Dockray, GJ; Jamieson, A; Louis, SM; Russell, NJ1
Imai, Y; Inoki, R; Shibutani, T; Yonehara, N1
Blumberg, PM; Szallasi, A1
Szolcsányi, J1
Andrews, PV; Eglezos, A; Helme, RD1
Markowitz, S; Moskowitz, MA; Saito, K2
Ahlstedt, S; Alving, K; Lundberg, JM; Ulfgren, AK1
LaHann, TR1
Andrews, PV; Helme, RD1
Helme, RD; McKernan, S1

Reviews

28 review(s) available for capsaicin and Innate Inflammatory Response

ArticleYear
5-Lipoxygenase as a drug target: A review on trends in inhibitors structural design, SAR and mechanism based approach.
    Bioorganic & medicinal chemistry, 2019, 09-01, Volume: 27, Issue:17

    Topics: Animals; Arachidonate 5-Lipoxygenase; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Molecular Structure; Structure-Activity Relationship

2019
Capsaicin and TRPV1 Channels in the Cardiovascular System: The Role of Inflammation.
    Cells, 2021, 12-22, Volume: 11, Issue:1

    Topics: Animals; Blood Vessels; Capsaicin; Cardiovascular System; Humans; Inflammation; TRPV Cation Channels; Vasodilation

2021
Capsaicin: A Potential Treatment to Improve Cerebrovascular Function and Cognition in Obesity and Ageing.
    Nutrients, 2023, Mar-22, Volume: 15, Issue:6

    Topics: Aging; Animals; Capsaicin; Cognition; Dementia; Humans; Inflammation; Obesity; Quality of Life; TRPV Cation Channels

2023
Capsaicin and Gut Microbiota in Health and Disease.
    Molecules (Basel, Switzerland), 2020, Dec-02, Volume: 25, Issue:23

    Topics: Animals; Antipruritics; Capsaicin; Gastrointestinal Microbiome; Humans; Inflammation

2020
Capsaicin: Plants of the Genus Capsicum and Positive Effect of Oriental Spice on Skin Health.
    Skin pharmacology and physiology, 2020, Volume: 33, Issue:6

    Topics: Animals; Capsaicin; Capsicum; Humans; Inflammation; Skin; Spices; TRPV Cation Channels

2020
Capsaicin: Friend or Foe in Skin Cancer and Other Related Malignancies?
    Nutrients, 2017, Dec-16, Volume: 9, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Capsicum; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models, Animal; Humans; Inflammation; Melanoma; Neoplasms; Skin Neoplasms

2017
Transient receptor potential ion channels: powerful regulators of cell function.
    Annals of surgery, 2014, Volume: 259, Issue:2

    Topics: Analgesics; Anti-Inflammatory Agents; Biomarkers; Calcium Channels; Capsaicin; Chronic Pain; Duloxetine Hydrochloride; Humans; Inflammation; Macrophages; Melanoma; Monocytes; Nerve Tissue Proteins; Pain, Postoperative; Respiratory Tract Diseases; Surgical Wound Infection; Thiophenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2014
Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Catechin; Colchicine; Curcumin; Humans; Imidazoles; Inflammation; Niacin; Resveratrol; Stilbenes

2014
Capsaicin, Nociception and Pain.
    Molecules (Basel, Switzerland), 2016, Jun-18, Volume: 21, Issue:6

    Topics: Analgesics; Capsaicin; Humans; Inflammation; Nociception; Pain; Spinal Cord; TRPV Cation Channels

2016
The Effect of Capsaicin on Salivary Gland Dysfunction.
    Molecules (Basel, Switzerland), 2016, Jun-25, Volume: 21, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Humans; Inflammation; Receptors, Muscarinic; Salivary Glands; Salivation; Sensory System Agents; TRPV Cation Channels

2016
Inflammatory components of adipose tissue as target for treatment of metabolic syndrome.
    Forum of nutrition, 2009, Volume: 61

    Topics: Adipose Tissue; Animals; Capsaicin; Diet; Humans; Inflammation; Metabolic Syndrome; Mice; Obesity; Spices

2009
TRPV1 as a cough sensor and its temperature-sensitive properties.
    Pulmonary pharmacology & therapeutics, 2011, Volume: 24, Issue:3

    Topics: Animals; Body Temperature; Bronchoconstriction; Capsaicin; Cough; Dose-Response Relationship, Drug; Fever; Humans; Inflammation; Rats; Temperature; TRPV Cation Channels

2011
Models of acute inflammation in the ear.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan

2003
Biochemical pharmacology of the vanilloid receptor TRPV1. An update.
    European journal of biochemistry, 2004, Volume: 271, Issue:10

    Topics: Animals; Capsaicin; Humans; Inflammation; Models, Molecular; Pain; Receptors, Drug

2004
Regulation of inflammatory responses by sensory neurons: molecular mechanism(s) and possible therapeutic applications.
    Current medicinal chemistry, 2006, Volume: 13, Issue:19

    Topics: Calcitonin Gene-Related Peptide; Capsaicin; Endotoxins; Gastric Mucosa; Hot Temperature; Humans; Inflammation; Lung; Neurons, Afferent; Shock, Septic; TRPV Cation Channels; Vasodilator Agents

2006
Neurogenic inflammation. A model for studying efferent actions of sensory nerves.
    Advances in experimental medicine and biology, 1996, Volume: 410

    Topics: Afferent Pathways; Animals; Capillary Leak Syndrome; Capsaicin; Carotid Body; Efferent Pathways; Endothelium, Vascular; Guinea Pigs; Inflammation; Mycoplasma Infections; Neovascularization, Pathologic; Neurons, Afferent; Rats; Receptors, Neurokinin-1; Respiratory System; Respiratory Tract Diseases; Respiratory Tract Infections; Substance P; Venules

1996
Potential role of tachykinins in inflammatory diseases.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:5

    Topics: Afferent Pathways; Anti-Inflammatory Agents; Capsaicin; Inflammation; Neuronal Plasticity; Receptors, Tachykinin; Sensory Receptor Cells; Tachykinins

1997
Efferent functions of C-fiber nociceptors.
    Zeitschrift fur Rheumatologie, 1998, Volume: 57 Suppl 2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Efferent Pathways; Fibromyalgia; Humans; Inflammation; Nerve Fibers; Neurokinin A; Nociceptors; Skin; Substance P; Swine

1998
Ion channels gated by heat.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jul-06, Volume: 96, Issue:14

    Topics: Animals; Capsaicin; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ion Channel Gating; Ion Channels; Nociceptors; Pain

1999
[Evaluation of various antagonists of CGRP, a neuromediator implicated in the inflammatory mechanisms of nasal mucosa].
    Schweizerische medizinische Wochenschrift, 2000, Volume: Suppl 125

    Topics: Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Humans; Inflammation; Nasal Mucosa

2000
[Neurogenic inflammation. I. Basic mechanisms, physiology and pharmacology].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2002, Volume: 37, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Inflammation; Nerve Fibers; Neuritis; Neurons, Afferent; Substance P

2002
Neurogenic inflammation and the oral mucosa.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:10

    Topics: Capsaicin; Humans; Inflammation; Mouth Mucosa; Neurons, Afferent; Sensory Receptor Cells; Substance P; Vasodilation

1992
Infections intensify neurogenic plasma extravasation in the airway mucosa.
    The American review of respiratory disease, 1992, Volume: 146, Issue:5 Pt 2

    Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Extravascular Lung Water; Guinea Pigs; Inflammation; Mucous Membrane; Neurons, Afferent; Rats; Respiratory System; Respiratory Tract Infections

1992
Calcitonin gene-related peptide in inflammatory bowel disease and experimentally induced colitis.
    Annals of the New York Academy of Sciences, 1992, Jun-30, Volume: 657

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis, Ulcerative; Colon; Denervation; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Neurons; Neurons, Afferent

1992
Chemical activation of nociceptive peripheral neurones.
    British medical bulletin, 1991, Volume: 47, Issue:3

    Topics: Bradykinin; Calcium-Transporting ATPases; Capsaicin; Humans; Inflammation; Ion Channels; Models, Neurological; Neurons; Nociceptors; Pain; Serotonin

1991
Functions of the nociceptive primary neurons.
    The Japanese journal of physiology, 1990, Volume: 40, Issue:1

    Topics: Afferent Pathways; Animals; Capsaicin; Humans; Inflammation; Mechanoreceptors; Neurons; Neuropeptides; Nociceptors; Reflex

1990
Neuropeptides and the pathogenesis of allergy.
    Allergy, 1987, Volume: 42, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Hypersensitivity; Inflammation; Mast Cells; Neurokinin A; Neuropeptides; Peripheral Nerves; Substance P

1987
Peptides and neurogenic inflammation.
    British medical bulletin, 1987, Volume: 43, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Inflammation; Nervous System; Neuropeptides; Substance P

1987

Trials

6 trial(s) available for capsaicin and Innate Inflammatory Response

ArticleYear
Capsaicin and Its Effect on Exercise Performance, Fatigue and Inflammation after Exercise.
    Nutrients, 2022, Jan-06, Volume: 14, Issue:2

    Topics: Athletic Performance; Bicycling; Capsaicin; Cross-Over Studies; Exercise; Exercise Test; Healthy Volunteers; Humans; Inflammation; Isometric Contraction; Male; Muscle Fatigue; Muscle, Skeletal; Performance-Enhancing Substances; Single-Blind Method; Young Adult

2022
Effects of treatment with montelukast alone, budesonide/formoterol alone and a combination of both in cough variant asthma.
    Respiratory research, 2022, Oct-10, Volume: 23, Issue:1

    Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Antitussive Agents; Asthma; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Capsaicin; Cough; Cyclopropanes; Formoterol Fumarate; Humans; Inflammation; Leukotriene Antagonists; Quinolines; Sulfides

2022
PIEZO2 mediates injury-induced tactile pain in mice and humans.
    Science translational medicine, 2018, 10-10, Volume: 10, Issue:462

    Topics: Animals; Capsaicin; Chronic Disease; Disease Models, Animal; Humans; Hyperalgesia; Imaging, Three-Dimensional; Inflammation; Ion Channels; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neurons; Pain; Recombination, Genetic; Touch

2018
Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats.
    Behavioural pharmacology, 2013, Volume: 24, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Edema; Furans; Ginkgolides; Hindlimb; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Sensory System Agents; Vocalization, Animal

2013
Topical Analgesic Nanolipid Vesicles Formulation of Capsaicinoids Extract of Bhut Jolokia (Capsicum chinense Jacq): Pharmacodynamic Evaluation in Rat Models and Acceptability studies in Human Volunteers.
    Current drug delivery, 2016, Volume: 13, Issue:8

    Topics: Administration, Topical; Analgesics; Animals; Arthritis, Experimental; Capsaicin; Capsicum; Carrageenan; Drug Carriers; Formaldehyde; Freund's Adjuvant; Healthy Volunteers; Humans; In Vitro Techniques; Inflammation; Male; Nanoparticles; Phosphatidylcholines; Phytotherapy; Plant Extracts; Rats, Wistar; Skin; Skin Absorption

2016
Oral capsaicin provides temporary relief for oral mucositis pain secondary to chemotherapy/radiation therapy.
    Journal of pain and symptom management, 1995, Volume: 10, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents; Capsaicin; Female; Humans; Inflammation; Male; Middle Aged; Mouth Diseases; Neoplasms; Pain; Pilot Projects; Radiotherapy; Time Factors; Treatment Outcome

1995

Other Studies

363 other study(ies) available for capsaicin and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.
    Journal of medicinal chemistry, 2018, 05-24, Volume: 61, Issue:10

    Topics: Administration, Topical; Analgesics, Non-Narcotic; Animals; Capsaicin; Cells, Cultured; Drug Discovery; Female; Humans; Inflammation; Keratinocytes; Laurates; Mice; Mice, Inbred C57BL; Skin Diseases; TRPV Cation Channels

2018
Inhibition of Spinal TRPV1 Reduces NMDA Receptor 2B Phosphorylation and Produces Anti-Nociceptive Effects in Mice with Inflammatory Pain.
    International journal of molecular sciences, 2021, Oct-16, Volume: 22, Issue:20

    Topics: Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Glutamic Acid; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred ICR; Pain; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Spinal Cord; TRPV Cation Channels

2021
Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway.
    International immunopharmacology, 2021, Volume: 101, Issue:Pt B

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Freund's Adjuvant; Ganglia, Spinal; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Male; Mice; Monoterpenes; Neurons; Receptors, G-Protein-Coupled; Succinic Acid; TRPV Cation Channels

2021
Lactobacillus rhamnosus attenuates Thai chili extracts induced gut inflammation and dysbiosis despite capsaicin bactericidal effect against the probiotics, a possible toxicity of high dose capsaicin.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Antipruritics; Capsaicin; Cytokines; Dysbiosis; Feces; Female; Gastrointestinal Tract; Humans; Inflammation; Lacticaseibacillus rhamnosus; Male; Mice; Mice, Inbred C57BL; Middle Aged; Plant Extracts; Probiotics; Tight Junctions; Young Adult

2021
Antinociceptive and Anti-inflammatory Effect of Corynoline in Different Nociceptive and Inflammatory Experimental Models.
    Applied biochemistry and biotechnology, 2022, Volume: 194, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Berberine Alkaloids; Capsaicin; Carrageenan; Cytokines; Edema; Formaldehyde; Glutamates; Inflammation; Inflammation Mediators; Mice; Models, Theoretical; Nociception; Pain; Plant Extracts; Water

2022
Inflammatory and contractile profile in LPS-challenged equine isolated bronchi: Evidence for IL-6 as a potential target against AHR in equine asthma.
    Pulmonary pharmacology & therapeutics, 2022, Volume: 73-74

    Topics: Animals; Asthma; Bronchi; Capsaicin; Horses; Inflammation; Interleukin-33; Interleukin-6; Lipopolysaccharides; Neurokinin A; Transforming Growth Factor beta

2022
Sensory testing and topical capsaicin can characterize patients with rheumatoid arthritis.
    Clinical rheumatology, 2022, Volume: 41, Issue:8

    Topics: Arthritis, Rheumatoid; Capsaicin; Humans; Inflammation; Middle Aged; Neuralgia; Sensory System Agents

2022
Emodin Reduces Inflammatory and Nociceptive Responses in Different Pain-and Inflammation-Induced Mouse Models.
    Combinatorial chemistry & high throughput screening, 2023, Volume: 26, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Emodin; Formaldehyde; Glutamates; Inflammation; Mice; Pain; Plant Extracts

2023
Effects of Electroacupuncture on Gastrointestinal Motility Function, Pain, and Inflammation
    Disease markers, 2022, Volume: 2022

    Topics: Animals; Capsaicin; Electroacupuncture; Gastrointestinal Motility; Inflammation; NF-kappa B; Pain; Rats; Tumor Necrosis Factor-alpha

2022
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
    Cell chemical biology, 2022, 08-18, Volume: 29, Issue:8

    Topics: Capsaicin; Carrier Proteins; Cyclooxygenase 2; Humans; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Membrane Proteins; Sepsis; Thyroid Hormone-Binding Proteins; Thyroid Hormones; TRPV Cation Channels

2022
Beneficial effects of capsaicin and dihydrocapsaicin on endothelial inflammation, nitric oxide production and antioxidant activity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154

    Topics: Antioxidants; Capsaicin; Capsicum; Endothelial Cells; Humans; Inflammation; Nitric Oxide; Tumor Necrosis Factor-alpha

2022
Curcumin and capsaicin regulate apoptosis and alleviate intestinal inflammation induced by Clostridioides difficile in vitro.
    Annals of clinical microbiology and antimicrobials, 2022, Sep-26, Volume: 21, Issue:1

    Topics: Anti-Inflammatory Agents; Apoptosis; Bacterial Toxins; Capsaicin; Clostridioides; Clostridioides difficile; Clostridium Infections; Curcumin; Humans; Inflammation; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2022
Water Extract of
    Nutrients, 2023, Feb-21, Volume: 15, Issue:5

    Topics: Animals; Capsaicin; Chrysanthemum; Fatty Acids, Volatile; Flowers; Gastrointestinal Microbiome; Inflammation; Lipopolysaccharides; Mice; Plant Extracts; Tumor Necrosis Factor-alpha

2023
Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies.
    Scientific reports, 2023, 05-27, Volume: 13, Issue:1

    Topics: Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Capsaicin; Curcumin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Docking Simulation; Spices

2023
Improvement of wound healing by capsaicin through suppression of the inflammatory response and amelioration of the repair process.
    Molecular medicine reports, 2023, Volume: 28, Issue:2

    Topics: Animals; Capsaicin; Cell Movement; Inflammation; Interleukin-6; Mice; Wound Healing

2023
Molecular Links between Sensory Nerves, Inflammation, and Pain 2.0.
    International journal of molecular sciences, 2023, Jul-31, Volume: 24, Issue:15

    Topics: Afferent Pathways; Capsaicin; Humans; Inflammation; Neurons, Afferent; Pain; Peripheral Nervous System

2023
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
    The European journal of neuroscience, 2023, Volume: 58, Issue:7

    Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chronic Pain; Formaldehyde; Ganglia, Spinal; Hyperalgesia; Inflammation; Methoxsalen; Mice

2023
Chronic pain models amplify transient receptor potential vanilloid 1 (TRPV1) receptor responses in adult rat spinal dorsal horn.
    Neuropharmacology, 2019, 12-01, Volume: 160

    Topics: Animals; Capsaicin; Chronic Pain; Disease Models, Animal; Excitatory Postsynaptic Potentials; Freund's Adjuvant; Inflammation; Male; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Substantia Gelatinosa; Synaptic Transmission; TRPV Cation Channels

2019
A systems biology approach to identify the key targets of curcumin and capsaicin that downregulate pro-inflammatory pathways in human monocytes.
    Computational biology and chemistry, 2019, Volume: 83

    Topics: Capsaicin; Cell Movement; Curcumin; Cytokines; Down-Regulation; Humans; Inflammation; Monocytes; Systems Biology; THP-1 Cells

2019
Abnormal Pain Sensation in Mice Lacking the Prokineticin Receptor PKR2: Interaction of PKR2 with Transient Receptor Potential TRPV1 and TRPA1.
    Neuroscience, 2020, 02-10, Volume: 427

    Topics: Amphibian Proteins; Animals; Capsaicin; Ganglia, Spinal; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Neuropeptides; Nociception; Pain; Plant Oils; Receptors, G-Protein-Coupled; TRPA1 Cation Channel; TRPV Cation Channels

2020
Effects of gabapentinoids on responses of primary cultures from rat dorsal root ganglia to inflammatory or somatosensory stimuli.
    Journal of basic and clinical physiology and pharmacology, 2020, Feb-20, Volume: 31, Issue:4

    Topics: Analgesics; Animals; Capsaicin; Female; Gabapentin; Ganglia, Spinal; Inflammation; Lipopolysaccharides; Male; Neuralgia; Neurons; Pregabalin; Primary Cell Culture; Rats; Rats, Wistar; Sensory System Agents; Somatosensory Cortex

2020
Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation and mesolimbic pathway.
    Toxicology and applied pharmacology, 2020, 09-01, Volume: 402

    Topics: Animals; Appetite Regulation; Capsaicin; Coloring Agents; Energy Metabolism; Female; Furans; Gene Expression Regulation; Glucose Tolerance Test; Hypoglycemic Agents; Hypothalamus; Inflammation; Metformin; Mice; Mice, Inbred BALB C; Motor Activity; Olanzapine; Ruthenium Red; Sensory System Agents; TRPV Cation Channels

2020
Capsaicin-Cyclodextrin Complex Enhances Mepivacaine Targeting and Improves Local Anesthesia in Inflamed Tissues.
    International journal of molecular sciences, 2020, Aug-10, Volume: 21, Issue:16

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anesthesia, Local; Anesthetics, Local; Animals; Calorimetry, Differential Scanning; Capsaicin; Carrageenan; Disease Models, Animal; Drug Compounding; Drug Stability; Drug Therapy, Combination; Excipients; Hyperalgesia; Inflammation; Magnetic Resonance Spectroscopy; Male; Mepivacaine; Mice; Microscopy, Electron, Scanning; Pain; Pain Management; Solubility; X-Ray Diffraction

2020
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.
    Gut, 2021, Volume: 70, Issue:7

    Topics: Adult; Animals; Capsaicin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enterobacteriaceae Infections; Female; Ganglia, Spinal; Histamine; Humans; Hypersensitivity; Inflammation; Irritable Bowel Syndrome; Male; Mice; Middle Aged; Neurons; Rats; Receptors, Cannabinoid; TRPV Cation Channels

2021
Responses of spinal trigeminal neurons to noxious stimulation of paranasal cavities - a rat model of rhinosinusitis headache.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:5

    Topics: Animals; Bradykinin; Capsaicin; Dura Mater; Electric Stimulation; Headache; Inflammation; Male; Neurons; Neurons, Afferent; Paranasal Sinuses; Potassium Chloride; Rats; Trigeminal Nuclei; Trigeminal Nucleus, Spinal; Vasodilator Agents

2021
Pharmacologycal activity of peperina (Minthostachys verticillata) on gastrointestinal tract.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Capsaicin; Castor Oil; Colitis, Ulcerative; Colon; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Hyperalgesia; Inflammation; Lamiaceae; Male; Mice; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Visceral Pain

2021
A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability.
    Scientific reports, 2021, 01-08, Volume: 11, Issue:1

    Topics: Capsaicin; Drug Discovery; Ganglia, Spinal; Histamine; Humans; Inflammation; Laurates; Sensory Receptor Cells; TRPV Cation Channels

2021
Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:4

    Topics: Animals; Biomarkers; Capsaicin; Carrageenan; Endocannabinoids; Flurbiprofen; Gene Expression Regulation; Hyperalgesia; Inflammation; Lipopolysaccharides; Male; Mice; Pain

2021
Pharmacological studies on aqueous extract of Launaea arborescens from southwest Algeria.
    Journal of ethnopharmacology, 2021, Jul-15, Volume: 275

    Topics: Algeria; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Behavior, Animal; Capsaicin; Edema; Formaldehyde; Histamine; Hot Temperature; Inflammation; Male; Medicine, Traditional; Mice, Inbred BALB C; Pain; Pain Measurement; Plant Extracts; Serotonin; Solutions; TRPV Cation Channels

2021
Quinoa (Chenopodium quinoa Willd.) Seeds Increase Intestinal Protein Uptake.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:13

    Topics: Animals; Caco-2 Cells; Capsaicin; Chenopodium quinoa; Cholera Toxin; Dietary Proteins; Female; Goblet Cells; Humans; Inflammation; Intestines; Male; Permeability; Rats; Seeds

2021
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:5

    Topics: Acrylamide; Animals; Benzoquinones; Capsaicin; Inflammation; Male; Occludin; Oxidative Stress; Rats; Tight Junctions

2022
Capsaicin affects macrophage anti-inflammatory activity via the MAPK and NF-κB signaling pathways.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2023, Volume: 93, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Cytokines; Female; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Signal Transduction; Tumor Necrosis Factor-alpha

2023
Inflammasome Signaling Regulates the Microbial-Neuroimmune Axis and Visceral Pain in Mice.
    International journal of molecular sciences, 2021, Aug-03, Volume: 22, Issue:15

    Topics: Animals; Anti-Bacterial Agents; Brain; Capsaicin; Caspase 1; Colon; Female; Gastrointestinal Microbiome; Inflammasomes; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroimmunomodulation; Signal Transduction; Visceral Pain

2021
Preparation and Evaluation of PLGA-Coated Capsaicin Magnetic Nanoparticles.
    Pharmaceutical research, 2017, Volume: 34, Issue:6

    Topics: Animals; Capsaicin; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Fluorescein; Fluorescent Dyes; HEK293 Cells; Humans; Inflammation; Lactic Acid; Magnetite Nanoparticles; Male; Mice, Inbred C57BL; Pain; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties

2017
Gut Microbiota Mediates the Protective Effects of Dietary Capsaicin against Chronic Low-Grade Inflammation and Associated Obesity Induced by High-Fat Diet.
    mBio, 2017, 05-23, Volume: 8, Issue:3

    Topics: Animals; Anti-Obesity Agents; Capsaicin; Cluster Analysis; Diet, High-Fat; Disease Models, Animal; DNA, Bacterial; DNA, Ribosomal; Dysbiosis; Gastrointestinal Microbiome; Gastrointestinal Tract; Inflammation; Mice; Obesity; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA

2017
TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 06-21, Volume: 37, Issue:25

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Capsaicin; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Fibers, Unmyelinated; Neuronal Plasticity; Peripheral Nervous System Diseases; Posterior Horn Cells; Receptors, AMPA; Synaptic Transmission

2017
Capsaicin reduces PLGA-induced fibrosis by promoting M2 macrophages and suppressing overall inflammatory Response.
    Journal of biomedical materials research. Part A, 2018, Volume: 106, Issue:9

    Topics: Animals; Arginase; Biomarkers; Cadherins; Capsaicin; Cell Adhesion; Collagen; Cytokines; Fibrosis; Gene Expression Regulation, Enzymologic; Inflammation; Kinetics; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peritoneum; Polylactic Acid-Polyglycolic Acid Copolymer; Prostheses and Implants; RAW 264.7 Cells; Up-Regulation

2018
Adult mouse sensory neurons on microelectrode arrays exhibit increased spontaneous and stimulus-evoked activity in the presence of interleukin-6.
    Journal of neurophysiology, 2018, 09-01, Volume: 120, Issue:3

    Topics: Action Potentials; Animals; Bradykinin; Capsaicin; Cell Culture Techniques; Cells, Cultured; Dinoprostone; Electric Stimulation; Ganglia, Spinal; Hot Temperature; Inflammation; Inflammation Mediators; Interleukin-6; Male; Mice; Microelectrodes; Nociceptors; Sensory Receptor Cells

2018
Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia.
    Pain, 2018, Volume: 159, Issue:11

    Topics: Acetylcysteine; Action Potentials; Animals; Biotinylation; Capsaicin; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Erythromycin; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Neurons; Patch-Clamp Techniques; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Signal Transduction; TRPV Cation Channels

2018
Activation of TRPV1 Prevents Salt-Induced Kidney Damage and Hypertension After Renal Ischemia-Reperfusion Injury in Rats.
    Kidney & blood pressure research, 2018, Volume: 43, Issue:4

    Topics: Acute Kidney Injury; Animals; Capsaicin; Hypertension; Inflammation; Ischemic Preconditioning; Oxidative Stress; Protective Agents; Rats; Reperfusion Injury; Sodium Chloride, Dietary; TRPV Cation Channels

2018
Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner.
    Neuropharmacology, 2018, Volume: 143

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Capsaicin; Cells, Cultured; Disease Models, Animal; Female; Freund's Adjuvant; gamma-Aminobutyric Acid; Ganglia, Spinal; Hindlimb; Inflammation; Isoquinolines; Mice, Inbred C57BL; Motor Activity; Receptor, trkA; Sensory Receptor Cells; TRPV Cation Channels; Urea

2018
Vti1b promotes TRPV1 sensitization during inflammatory pain.
    Pain, 2019, Volume: 160, Issue:2

    Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Humans; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Qb-SNARE Proteins; RNA Interference; Sensory Receptor Cells; Signal Transduction; TRPV Cation Channels

2019
Dual enkephalinase inhibitor PL265: a novel topical treatment to alleviate corneal pain and inflammation.
    Pain, 2019, Volume: 160, Issue:2

    Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Benzalkonium Compounds; Capsaicin; Cornea; Corneal Injuries; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Pain; Pain Threshold; Propionates; Sensory System Agents; Trigeminal Ganglion

2019
Diosmetin as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive activity in mice.
    Life sciences, 2019, Jan-01, Volume: 216

    Topics: Analgesics; Animals; Calcium; Capsaicin; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Flavonoids; Inflammation; Male; Mice; Neuralgia; Pain; Pain Measurement; Spinal Cord; Synaptosomes; Toxicity Tests; TRPV Cation Channels

2019
Enhancing analgesic and anti-inflammatory effects of capsaicin when loaded into olive oil nanoemulsion: An in vivo study.
    International journal of pharmaceutics, 2019, Mar-25, Volume: 559

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chemistry, Pharmaceutical; Drug Carriers; Edema; Emulsions; Gels; Inflammation; Male; Nanoparticles; Olive Oil; Pain; Rabbits; Rats; Rats, Wistar; Skin Absorption

2019
Inhibition of Muscular Nociceptive Afferents via the Activation of Cutaneous Nociceptors in a Rat Model of Inflammatory Muscle Pain.
    Neuroscience bulletin, 2020, Volume: 36, Issue:1

    Topics: Animals; Capsaicin; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Irritants; Mentha piperita; Models, Animal; Mustard Plant; Myalgia; Neurons, Afferent; Nociceptive Pain; Nociceptors; Physical Stimulation; Plant Oils; Rats; Rats, Sprague-Dawley; Skin

2020
Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.
    Molecular pain, 2013, Feb-19, Volume: 9

    Topics: Animals; Behavior, Animal; Biopterins; Biosynthetic Pathways; Capsaicin; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Disease Models, Animal; Dystonic Disorders; Formaldehyde; Freund's Adjuvant; GTP Cyclohydrolase; Hot Temperature; Inflammation; Inheritance Patterns; Mice; Mice, Inbred C57BL; Motor Activity; Nociception; Pain; Phenylketonurias; Physical Stimulation; Rats; Stress, Mechanical

2013
Capsaicin-sensitive vagal afferent neurons contribute to the detection of pathogenic bacterial colonization in the gut.
    Journal of neuroimmunology, 2013, Apr-15, Volume: 257, Issue:1-2

    Topics: Animals; Campylobacter Infections; Capsaicin; Colony Count, Microbial; Gastrointestinal Tract; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Salmonella Infections; Vagus Nerve

2013
Antiallodynic and analgesic effects of maslinic acid, a pentacyclic triterpenoid from Olea europaea.
    Journal of natural products, 2013, Apr-26, Volume: 76, Issue:4

    Topics: Analgesics; Animals; Capsaicin; gamma-Aminobutyric Acid; Hyperalgesia; Inflammation; Mice; Molecular Structure; Olea; Pain; Pain Measurement; Pregabalin; Rotarod Performance Test; Time Factors; Triterpenes

2013
Acute stress regulates nociception and inflammatory response induced by bee venom in rats: possible mechanisms.
    Stress (Amsterdam, Netherlands), 2013, Volume: 16, Issue:5

    Topics: Animals; Bee Venoms; Capsaicin; Disease Models, Animal; Edema; Hindlimb; Hyperalgesia; Inflammation; Male; Naloxone; Nociception; Oxidopamine; Pain; Rats; Rats, Sprague-Dawley; Restraint, Physical; Sciatic Nerve; Stress, Psychological; Sympathetic Nervous System

2013
Vitexin inhibits inflammatory pain in mice by targeting TRPV1, oxidative stress, and cytokines.
    Journal of natural products, 2013, Jun-28, Volume: 76, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Apigenin; Benzoquinones; Capsaicin; Carrageenan; Cytokines; Disease Models, Animal; Freund's Adjuvant; Glycosides; Hyperalgesia; Inflammation; Male; Mice; Molecular Structure; Oxidative Stress; Pain; Plant Extracts; TRPV Cation Channels

2013
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetone; Acrolein; Acrylamides; Acute Disease; Alkaloids; Analgesics; Animals; Aporphines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Pain; Cold Temperature; Freund's Adjuvant; Gene Expression; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Transient Receptor Potential Channels; TRPA1 Cation Channel

2013
Activation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-α-induced inflammation in macrophages: role of liver X receptor α.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Animals; Atherosclerosis; Blotting, Western; Calcium; Capsaicin; Cells, Cultured; Chromatin Immunoprecipitation; Inflammation; Lipoproteins, LDL; Liver X Receptors; Macrophages; Mice; Orphan Nuclear Receptors; RNA, Small Interfering; TRPV Cation Channels; Tumor Necrosis Factor-alpha

2013
Protective effect of fenspiride on the bronchi in rats with chronic obstructive pulmonary disease.
    Bulletin of experimental biology and medicine, 2013, Volume: 155, Issue:2

    Topics: Animals; Bronchi; Bronchodilator Agents; Capsaicin; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Nerve Fibers, Unmyelinated; Nitrogen Dioxide; Procaine; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Wistar; Spiro Compounds; Tachykinins

2013
Comparative anti-inflammatory properties of Capsaicin and ethyl-aAcetate extract of Capsicum frutescens linn [Solanaceae] in rats.
    African health sciences, 2013, Volume: 13, Issue:2

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Capsicum; Dose-Response Relationship, Drug; Inflammation; Phytotherapy; Plant Extracts; Plant Preparations; Random Allocation; Rats; Solanaceae

2013
Trigeminal nerve stimulation triggers oral mast cell activation and vascular permeability.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2014, Volume: 112, Issue:1

    Topics: Animals; Antipruritics; Capillary Permeability; Capsaicin; Evans Blue; Inflammation; Male; Mast Cells; Mouth; Rats; Rats, Sprague-Dawley; Substance P; Transcutaneous Electric Nerve Stimulation; Trigeminal Nerve

2014
Polypeptide modulators of TRPV1 produce analgesia without hyperthermia.
    Marine drugs, 2013, Dec-16, Volume: 11, Issue:12

    Topics: Analgesia; Analgesics; Animals; Body Temperature; Capsaicin; Cell Line; Disease Models, Animal; Fever; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Male; Mice; Pain; Peptides; TRPV Cation Channels

2013
Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.
    Journal of medicinal food, 2014, Volume: 17, Issue:6

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Dextrans; Edema; Formaldehyde; Glutamic Acid; Histamine; Inflammation; Male; Mice; Naloxone; Pain; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Rats, Wistar; Sterculia

2014
The chemerin receptor 23 agonist, chemerin, attenuates monosynaptic C-fibre input to lamina I neurokinin 1 receptor expressing rat spinal cord neurons in inflammatory pain.
    Molecular pain, 2014, Apr-09, Volume: 10

    Topics: Action Potentials; Adipokines; Animals; Capsaicin; Chemokines; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Freund's Adjuvant; In Vitro Techniques; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Nerve Fibers, Unmyelinated; Neurons; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Spinal Cord

2014
Somatostatin 4 receptor activation modulates TRPV1[correction of TPRV1] currents in dorsal root ganglion neurons.
    Neuroscience letters, 2014, Jun-24, Volume: 573

    Topics: Animals; Butanes; Calcium; Capsaicin; Cells, Cultured; Freund's Adjuvant; Ganglia, Spinal; Inflammation; Male; Naphthalenes; Neurons; Nociception; Pain; Pertussis Toxin; Rats; Receptors, Somatostatin; Sulfones; TRPV Cation Channels

2014
LASSBio-1135: a dual TRPV1 antagonist and anti-TNF-alpha compound orally effective in models of inflammatory and neuropathic pain.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Administration, Oral; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Enzyme Activation; Female; Hydrogen-Ion Concentration; Hyperalgesia; Imidazoles; Inflammation; Macrophages, Peritoneal; MAP Kinase Signaling System; Mice, Inbred BALB C; Neuralgia; Neutrophil Infiltration; Oocytes; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Time Factors; TRPV Cation Channels; Tumor Necrosis Factor-alpha; Xenopus laevis

2014
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells.
    Nature immunology, 2014, Volume: 15, Issue:11

    Topics: Anilides; Animals; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; CD4-Positive T-Lymphocytes; Cells, Cultured; Cinnamates; Colitis; Humans; Inflammation; Interleukin-10; Intestines; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Antigen, T-Cell; Sensory System Agents; TRPV Cation Channels

2014
Mass-spectrometric identification of T-kininogen I/thiostatin as an acute-phase inflammatory protein suppressed by curcumin and capsaicin.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Acute-Phase Proteins; Animals; Arachidonic Acid; Capsaicin; Curcumin; Diet; Disease Models, Animal; Glycoproteins; Inflammation; Kininogens; Male; Mass Spectrometry; Rats; Rats, Wistar; Reactive Oxygen Species

2014
Sphingosine 1-phosphate to p38 signaling via S1P1 receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons.
    Molecular pain, 2014, Nov-28, Volume: 10

    Topics: Animals; Capsaicin; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Ions; Lysophospholipids; Male; Mice; Neurons, Afferent; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Proprotein Convertases; Sensory Receptor Cells; Serine Endopeptidases; Signal Transduction; Sphingosine

2014
Inflammation-induced increase in nicotinic acetylcholine receptor current in cutaneous nociceptive DRG neurons from the adult rat.
    Neuroscience, 2015, Jan-22, Volume: 284

    Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Ganglia, Spinal; Hindlimb; Inflammation; Male; Membrane Potentials; Neuroanatomical Tract-Tracing Techniques; Nicotine; Nicotinic Agonists; Nociceptors; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, Nicotinic; Sensory System Agents; Skin

2015
Inflammatory pain models with capsaicin or glutamate injections: are they comparable and reproducible?
    Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:12

    Topics: Capsaicin; Glutamic Acid; Humans; Inflammation; Pain; Reproducibility of Results

2014
Nanomiemgel--a novel drug delivery system for topical application--in vitro and in vivo evaluation.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Administration, Cutaneous; Aminoquinolines; Animals; Capsaicin; Cell Proliferation; Diclofenac; Disease Models, Animal; Drug Delivery Systems; Drug Stability; Emulsions; Gels; Humans; Imiquimod; Immunohistochemistry; In Vitro Techniques; Inflammation; Keratinocytes; Micelles; Microdialysis; Microscopy, Atomic Force; Nanoparticles; Organ Size; Permeability; Psoriasis; Rats; Rheology; Skin Absorption; Spleen

2014
The role of TRPV1 channels in carrageenan-induced mechanical hyperalgesia in mice.
    Neuroreport, 2015, Feb-11, Volume: 26, Issue:3

    Topics: Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Functional Laterality; Hyperalgesia; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Sensory System Agents; Touch; TRPV Cation Channels

2015
Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.
    Anesthesia and analgesia, 2015, Volume: 120, Issue:4

    Topics: Analgesics, Opioid; Calcium; Calcium Channels; Capsaicin; Electrophysiological Phenomena; HEK293 Cells; Humans; Inflammation; Isothiocyanates; Membrane Potentials; Nerve Tissue Proteins; Patch-Clamp Techniques; Receptors, Opioid, mu; Tramadol; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2015
A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis.
    Pain, 2015, Volume: 156, Issue:5

    Topics: Activating Transcription Factor 3; Amidohydrolases; Anilides; Animals; Arachidonic Acids; Benzamides; Capsaicin; Carbamates; Cinnamates; Disease Models, Animal; Endocannabinoids; Ganglia, Spinal; Gene Expression; Hyperalgesia; Inflammation; Interleukin-6; Lumbar Vertebrae; Male; Osteoarthritis; Pain; Pain Management; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; TRPV Cation Channels

2015
[A novel role for the TRPV1 ion channel in CD4 T cell activation].
    Medecine sciences : M/S, 2015, Volume: 31, Issue:2

    Topics: Animals; Calcium Signaling; Capsaicin; CD4 Antigens; CD4-Positive T-Lymphocytes; Humans; Inflammation; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphokines; Mice; Mice, Knockout; Protein Interaction Mapping; TRPV Cation Channels

2015
Shp-1 dephosphorylates TRPV1 in dorsal root ganglion neurons and alleviates CFA-induced inflammatory pain in rats.
    Pain, 2015, Volume: 156, Issue:4

    Topics: Animals; Calcium; Capsaicin; Cell Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Inflammation; Male; Membrane Potentials; Neurons; Pain; Pain Threshold; Patch-Clamp Techniques; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Sprague-Dawley; TRPV Cation Channels

2015
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 81

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinogenesis; Cyclooxygenase 2; Female; Hyperplasia; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation

2015
HDAC4 is required for inflammation-associated thermal hypersensitivity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:8

    Topics: Animals; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Down-Regulation; Freund's Adjuvant; Histone Deacetylases; Hyperalgesia; Hypersensitivity; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nociception; Pain; Protein Precursors; Sensory Receptor Cells; Transcription, Genetic; TRPV Cation Channels

2015
Synovial TRPV1 is upregulated by 17-β-estradiol and involved in allodynia of inflamed temporomandibular joints in female rats.
    Archives of oral biology, 2015, Volume: 60, Issue:9

    Topics: Animals; Blotting, Western; Capsaicin; Cyclooxygenase 2; Estradiol; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Nerve Growth Factor; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Temporomandibular Joint; Temporomandibular Joint Disorders; Transcriptional Activation; TRPV Cation Channels; Up-Regulation

2015
Therapeutic effects of naringin in a guinea pig model of ovalbumin-induced cough-variant asthma.
    Pulmonary pharmacology & therapeutics, 2015, Volume: 33

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cough; Disease Models, Animal; Flavanones; Guinea Pigs; Inflammation; Male; Ovalbumin

2015
Selective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alata.
    The Journal of biological chemistry, 2016, Jan-08, Volume: 291, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Capsaicin; Coumarins; Ganglia, Spinal; HEK293 Cells; Humans; Inflammation; Ion Channel Gating; Magnetic Resonance Spectroscopy; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Murraya; Neurons; Nociceptors; Pain; Rats; TRPV Cation Channels

2016
TRPV1 channel modulation by hyaluronan reduces pain.
    Channels (Austin, Tex.), 2016, Volume: 10, Issue:2

    Topics: Action Potentials; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Extracellular Matrix; HEK293 Cells; Hot Temperature; Humans; Hyaluronic Acid; Inflammation; Injections, Intra-Articular; Ion Channel Gating; Knee Joint; Neuralgia; TRPV Cation Channels

2016
Nonparalytic botulinum molecules for the control of pain.
    Pain, 2016, Volume: 157, Issue:5

    Topics: Animals; Botulinum Toxins, Type A; Capsaicin; Cell Count; Cell Proliferation; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Keratinocytes; Male; Motor Activity; Nerve Fibers, Unmyelinated; Neuralgia; Neuromuscular Agents; Pain Measurement; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn

2016
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase.
    Molecular pain, 2016, Volume: 12

    Topics: Acrylamides; Amidohydrolases; Analgesia; Animals; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Carrageenan; Disease Models, Animal; Ethanolamines; Formaldehyde; Genotype; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Ligands; Lumbar Vertebrae; Mice, Inbred C57BL; Mice, Knockout; Nociception; Pain; Pain Threshold; Phenotype; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Receptor, Cannabinoid, CB1; Skin; Spinal Cord Dorsal Horn; TRPV Cation Channels

2016
Dihydrocapsaicin suppresses proinflammatory cytokines expression by enhancing nuclear factor IA in a NF-κB-dependent manner.
    Archives of biochemistry and biophysics, 2016, 08-15, Volume: 604

    Topics: Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Capsaicin; Cytokines; Gene Expression Profiling; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; NF-kappa B; NFI Transcription Factors; RNA, Small Interfering; Tumor Necrosis Factor-alpha

2016
Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain.
    Scientific reports, 2016, 06-30, Volume: 6

    Topics: Acetanilides; Analgesics; Animals; Anti-Inflammatory Agents; Calcium Signaling; Capsaicin; HEK293 Cells; Humans; Inflammation; Mice; Mice, Knockout; Mustard Plant; Oximes; Pain; Plant Oils; Purines; TRPA1 Cation Channel

2016
Genotype-dependent responsivity to inflammatory pain: A role for TRPV1 in the periaqueductal grey.
    Pharmacological research, 2016, Volume: 113, Issue:Pt A

    Topics: Animals; Anxiety; Behavior, Animal; Capsaicin; Depression; Diterpenes; Genotype; Inflammation; Male; Pain; Periaqueductal Gray; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; RNA, Messenger; TRPV Cation Channels

2016
The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel.
    Molecular pain, 2016, Volume: 12

    Topics: Alkaloids; Animals; Anthelmintics; Antibiotics, Antineoplastic; Capsaicin; Cells, Cultured; Cesium; Chlorides; Enzyme Inhibitors; Freund's Adjuvant; Ganglia, Spinal; Gene Expression; Guanidines; HEK293 Cells; HSC70 Heat-Shock Proteins; Humans; Inflammation; Matrines; Mice; Neurons; Pain; Potassium Channel Blockers; Quinolizines; Rats; TRPV Cation Channels

2016
Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain.
    Molecular pain, 2016, Volume: 12

    Topics: Animals; Capsaicin; Cell-Penetrating Peptides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Inflammation; Lipopeptides; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Pain Threshold; Piperidines; Protein Kinase C; Rats; Rats, Long-Evans; Sex Characteristics; Spinal Cord

2016
SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons.
    Neuron, 2016, Dec-21, Volume: 92, Issue:6

    Topics: Animals; Behavior, Animal; Blotting, Western; Capsaicin; Ganglia, Spinal; Humans; Hyperalgesia; Immunohistochemistry; Inflammation; Mice; Mice, Knockout; Microfilament Proteins; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neuralgia; Pain; Patch-Clamp Techniques; Presynaptic Terminals; Reverse Transcriptase Polymerase Chain Reaction; Sensory Receptor Cells; Sensory System Agents; Spinal Cord; TRPV Cation Channels

2016
High-concentration topical capsaicin may abolish the clinical manifestations of allergic contact dermatitis by effects on induction and elicitation.
    Medical hypotheses, 2017, Volume: 99

    Topics: Administration, Cutaneous; Allergens; Capsaicin; Cytokines; Dermatitis, Allergic Contact; Humans; Inflammation; Lymph Nodes; Models, Theoretical; Neuropeptides; Skin

2017
Catecholamines reduce transient receptor potential vanilloid type 1 desensitization in cultured dorsal root ganglia neurons.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:6

    Topics: Adrenergic Antagonists; Animals; Calcium; Capsaicin; Catecholamines; Cells, Cultured; Epinephrine; Ganglia, Spinal; Inflammation; Male; Neurons; Norepinephrine; Pain; Rats; Rats, Wistar; Receptors, Adrenergic; Skin; TRPV Cation Channels

2016
Capsaicin pretreatment reversed pulmonary arterial hypertension by alleviating inflammation via p38MAPK pathway.
    Experimental lung research, 2017, Volume: 43, Issue:1

    Topics: Animals; Capsaicin; Hypertension, Pulmonary; Inflammation; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Premedication; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling

2017
Behavioral and electrophysiological evidence for the differential functions of TRPV1 at early and late stages of chronic inflammatory nociception in rats.
    Neurochemical research, 2008, Volume: 33, Issue:10

    Topics: Animals; Capsaicin; Chronic Disease; Electric Stimulation; Evoked Potentials; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Injections, Spinal; Male; Pain; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; TRPV Cation Channels

2008
G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia.
    Brain, behavior, and immunity, 2009, Volume: 23, Issue:1

    Topics: Analysis of Variance; Animals; Blotting, Western; Capsaicin; Cell Line; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; G-Protein-Coupled Receptor Kinases; Hyperalgesia; Inflammation; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Pain Threshold; Peroxidase; Proto-Oncogene Proteins c-fos; Visceral Afferents

2009
Ultraviolet-B induced inflammation of human skin: characterisation and comparison with traditional models of hyperalgesia.
    European journal of pain (London, England), 2009, Volume: 13, Issue:5

    Topics: Adult; Burns; Capsaicin; Female; Hot Temperature; Humans; Hyperalgesia; Inflammation; Male; Models, Neurological; Nociceptors; Pain Threshold; Radiation Dosage; Sensory Receptor Cells; Sensory System Agents; Skin; Sunburn; Time Factors; Ultraviolet Rays; Young Adult

2009
Increases in transient receptor potential vanilloid-1 mRNA and protein in primary afferent neurons stimulated by protein kinase C and their possible role in neurogenic inflammation.
    Journal of neuroscience research, 2009, Volume: 87, Issue:2

    Topics: Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Fluorescent Antibody Technique; Ganglia, Spinal; Gene Expression; Immunohistochemistry; Inflammation; Male; Microscopy, Confocal; Neurons, Afferent; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensory System Agents; TRPV Cation Channels; Up-Regulation

2009
TNBS-induced inflammation modulates the function of one class of low-threshold rectal mechanoreceptors in the guinea pig.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:4

    Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Inflammation; Inflammation Mediators; Male; Mechanoreceptors; Muscle Contraction; Rectum; Trinitrobenzenesulfonic Acid

2008
Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Administration, Oral; Animals; Benzothiazoles; Capsaicin; Cell Line; Chemistry, Pharmaceutical; Drug Design; Guinea Pigs; Humans; Inflammation; Inhibitory Concentration 50; Models, Chemical; Niacinamide; Rats; TRPV Cation Channels

2008
Change of AMPA receptors in spinal nociceptive synapses during inflammatory hyperalgesia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Oct-08, Volume: 28, Issue:41

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Humans; Hyperalgesia; Inflammation; Long-Term Potentiation; Nociceptors; Receptors, AMPA; Sensory System Agents; Spinal Cord; Synapses; Synaptic Transmission

2008
Acid increases inflammatory pain in rats: effect of local peripheral ASICs inhibitors.
    European journal of pharmacology, 2009, Jan-28, Volume: 603, Issue:1-3

    Topics: Acid Sensing Ion Channels; Amiloride; Analgesics; Animals; Capsaicin; Female; Formaldehyde; Hydrogen-Ion Concentration; Inflammation; Nerve Tissue Proteins; Pain; Rats; Rats, Wistar; Serotonin; Sodium Channels

2009
Tumor bearing decreases systemic acute inflammation in rats--role of mast cell degranulation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009, Volume: 58, Issue:5

    Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Carrageenan; Cell Degranulation; Dextrans; Edema; Histamine; Inflammation; Mast Cells; Neoplasm Transplantation; Neoplasms; Neutrophil Activation; Neutrophil Infiltration; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Substance P

2009
Prophylactic proopiomelanocortin expression alleviates capsaicin-induced neurogenic inflammation in rat trachea.
    Shock (Augusta, Ga.), 2009, Volume: 32, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Cell Line; Cell Movement; Gene Expression Regulation; Humans; Inflammation; Male; Melanocortins; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Time Factors; Trachea

2009
Interleukin-1alpha regulates substance P expression and release in adult sensory neurons.
    Experimental neurology, 2009, Volume: 217, Issue:2

    Topics: Age Factors; Animals; Capsaicin; Cells, Cultured; Female; Ganglia, Spinal; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Nerve Growth Factor; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Substance P; Up-Regulation

2009
Antinociceptive and anti-allodynic effects of 3-alkynyl selenophene on different models of nociception in mice.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:4

    Topics: Analgesics; Animals; Bradykinin; Capsaicin; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Hot Temperature; Hyperalgesia; Immersion; Inflammation; Male; Mice; Motor Activity; Organoselenium Compounds; Pain Measurement; Reaction Time; Tetradecanoylphorbol Acetate

2009
Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:4

    Topics: Adiponectin; Adipose Tissue; Animals; Anti-Inflammatory Agents; Blood Glucose; Capsaicin; Dietary Fats; Dietary Supplements; Disease Models, Animal; Fatty Liver; Flow Cytometry; Gene Expression; Glucose Intolerance; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Leptin; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; PPAR alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides; TRPV Cation Channels

2010
Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons.
    The Journal of biological chemistry, 2010, Feb-19, Volume: 285, Issue:8

    Topics: Action Potentials; Animals; Aquaporin 1; Bradykinin; Capsaicin; Cell Line, Tumor; Dinoprostone; Ganglia, Spinal; Gene Expression Regulation; Inflammation; Mice; Mice, Knockout; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Oxytocics; Pain; Pain Management; Perception; Sensory System Agents; Sodium Channels; Vasodilator Agents

2010
The effects of sympathetic outflow on upregulation of vanilloid receptors TRPV(1) in primary afferent neurons evoked by intradermal capsaicin.
    Experimental neurology, 2010, Volume: 222, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Drug Administration Routes; Functional Laterality; Ganglia, Spinal; Inflammation; Male; Metacarpus; Neurons, Afferent; Protein Kinase C; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sensory System Agents; Sympathectomy; TRPV Cation Channels; Up-Regulation

2010
Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signaling.
    Free radical biology & medicine, 2010, May-01, Volume: 48, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Capsaicin; Cell Line; Cell Survival; Dermatitis; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Immunohistochemistry; Inflammation; Keratinocytes; Mice; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; src-Family Kinases; Ultraviolet Rays

2010
The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice.
    Pharmacological research, 2010, Volume: 61, Issue:6

    Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Benzamides; Capsaicin; Carbamates; Carrageenan; Hyperalgesia; Inflammation; Mice; Receptor, Cannabinoid, CB1; Serotonin; TRPV Cation Channels

2010
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Analgesics; Animals; Biological Availability; Capsaicin; Chlorocebus aethiops; COS Cells; Hot Temperature; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Microsomes, Liver; Naphthyridines; Pain; Pyrazines; Pyridines; Pyrimidines; Quinazolines; Quinolines; Rats; Structure-Activity Relationship; TRPV Cation Channels

2010
Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in the spinal cord dorsal horn of rats with neuropathic and inflammatory pain.
    Journal of neurochemistry, 2010, Volume: 114, Issue:1

    Topics: Animals; Capsaicin; Glutamic Acid; Inflammation; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Posterior Horn Cells; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate

2010
Cholecystokinin/Cholecystokinin-1 receptor-mediated peripheral activation of the afferent vagus by enteral nutrients attenuates inflammation in rats.
    Annals of surgery, 2010, Volume: 252, Issue:2

    Topics: Animals; Bacterial Translocation; Capsaicin; Cholecystokinin; Enteral Nutrition; Inflammation; Intestinal Absorption; Lipids; Male; Neural Pathways; Peptide Fragments; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Shock, Hemorrhagic; Vagus Nerve

2010
Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid-containing immune cells to inhibit inflammatory pain.
    Brain, behavior, and immunity, 2010, Volume: 24, Issue:8

    Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Endorphins; Endothelium, Vascular; Flow Cytometry; Freund's Adjuvant; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Male; Nerve Fibers; Oxidopamine; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Sensory Receptor Cells; Sympathetic Nervous System; Sympatholytics; Tyrosine 3-Monooxygenase

2010
NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing loss.
    Antioxidants & redox signaling, 2011, Mar-15, Volume: 14, Issue:6

    Topics: Animals; Capsaicin; Cells, Cultured; Cochlea; Evoked Potentials; Hearing Loss; Immunohistochemistry; Inflammation; Male; Mice; Microscopy, Electron, Scanning; NADPH Oxidases; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; STAT1 Transcription Factor; TRPV Cation Channels

2011
Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels.
    Experimental neurology, 2010, Volume: 226, Issue:1

    Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bupivacaine; Capsaicin; Ganglia, Spinal; Indomethacin; Inflammation; Male; Morphine; Neurons; Pain; Pain Measurement; Patch-Clamp Techniques; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Sodium Channel Blockers

2010
Cutaneous limb inflammation produces analgesia to pressure pain in the ipsilateral forehead of healthy volunteers.
    The journal of pain, 2011, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Analgesia; Capsaicin; Complex Regional Pain Syndromes; Female; Forearm; Forehead; Functional Laterality; Humans; Hyperalgesia; Inflammation; Irritants; Pain; Pain Perception; Pain Threshold; Pressure; Skin; Young Adult

2011
C-fibers, but not the transient potential receptor vanilloid 1 (TRPV1), play a role in experimental allergic airway inflammation.
    European journal of pharmacology, 2011, Jul-15, Volume: 662, Issue:1-3

    Topics: Allergens; Anilides; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cinnamates; Cytokines; Female; Gene Expression Regulation; Hypersensitivity; Immunization; Inflammation; Leukocytes; Lung; Mice; Mice, Inbred BALB C; Nerve Fibers, Unmyelinated; NF-kappa B; Ovalbumin; P-Selectin; Respiratory System; TRPV Cation Channels

2011
TRPM3 is a nociceptor channel involved in the detection of noxious heat.
    Neuron, 2011, May-12, Volume: 70, Issue:3

    Topics: Acrylamides; Animals; Behavior, Animal; Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Capsaicin; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Hot Temperature; Humans; Hyperalgesia; Inflammation; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Nifedipine; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Plant Oils; Pregnenolone; Sensory Receptor Cells; Telemetry; Time Factors; Transfection; Transient Receptor Potential Channels; Trigeminal Ganglion; TRPA1 Cation Channel; TRPM Cation Channels

2011
17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception.
    British journal of pharmacology, 2012, Volume: 165, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Cell Line; Docosahexaenoic Acids; Freund's Adjuvant; Ganglia, Spinal; HEK293 Cells; Hot Temperature; Humans; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Pain; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; TRPV Cation Channels

2012
Capsaicin induces reflex scratching in inflamed skin.
    Pharmacology, 2011, Volume: 88, Issue:1-2

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Capsaicin; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Freund's Adjuvant; Inflammation; Injections, Intradermal; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Pain; Pruritus; Receptors, Opioid, mu; Reflex; Sensory System Agents; Skin; Time Factors; TRPV Cation Channels

2011
Spinal glycinergic and GABAergic neurons expressing C-fos after capsaicin stimulation are increased in rats with contralateral neuropathic pain.
    Neuroscience, 2011, Nov-24, Volume: 196

    Topics: Animals; Capsaicin; Freund's Adjuvant; Functional Laterality; GABAergic Neurons; Glycine; Inflammation; Male; Molecular Imaging; Neuralgia; Neurons; Pain; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord

2011
Persistent epithelial barrier alterations in a rat model of postinfectious gut dysfunction.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:11

    Topics: Animals; Capsaicin; Chymases; Enteric Nervous System; Gastrointestinal Tract; Inflammation; Intestinal Mucosa; Ion Transport; Male; Mast Cells; Mastocytosis; Neurotransmitter Agents; Permeability; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Substance P; Tetrodotoxin; Trichinella spiralis; Trichinellosis

2011
Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Capsaicin; Cell Nucleus; Chemokines; Cytokines; Extracellular Signal-Regulated MAP Kinases; Hydrogen Sulfide; Inflammation; Male; Mice; NF-kappa B; Phosphorylation; Sepsis; Substance P; TRPV Cation Channels

2011
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Death; Cell Line; Cell Line, Transformed; Cells, Cultured; Endoplasmic Reticulum Stress; Humans; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Alveoli; Pulmonary Edema; Transcription Factor CHOP; TRPV Cation Channels

2012
Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Axons; Capsaicin; Cells, Cultured; Immunoblotting; Inflammation; Male; Mice; Mice, Knockout; Neuregulin-1; Pain; Patch-Clamp Techniques; Sensation; Sensory Receptor Cells; Sensory System Agents; Signal Transduction; Thermosensing; TRPV Cation Channels

2011
Metabotropic glutamate antagonists alone and in combination with morphine: comparison across two models of acute pain and a model of persistent, inflammatory pain.
    Behavioural pharmacology, 2011, Volume: 22, Issue:8

    Topics: Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Inflammation; Male; Morphine; Narcotics; Pain; Pain Measurement; Pyridines; Quinolines; Rats; Rats, Inbred F344; Receptors, Metabotropic Glutamate

2011
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
    Journal of pharmacological sciences, 2011, Volume: 117, Issue:3

    Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde; Glycyrrhetinic Acid; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ligation; Male; Neuralgia; Neurokinin A; Neurokinin B; Pain; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Sciatic Nerve; Substance P

2011
Influence of influenza A infection on capsaicin-induced responses in murine airways.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones

2012
Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats.
    Journal of pharmacological sciences, 2012, Volume: 118, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Bradykinin; Capsaicin; Carrageenan; Chalcone; Cyclooxygenase 2; Drugs, Chinese Herbal; Ganglia, Spinal; Inflammation; Male; Pain; Plant Extracts; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve; Substance P; Tachykinins

2012
Transient receptor potential vanilloid 1 - a polymodal nociceptive receptor - plays a crucial role in formaldehyde-induced skin inflammation in mice.
    Journal of pharmacological sciences, 2012, Volume: 118, Issue:2

    Topics: Animals; Capsaicin; Disease Models, Animal; Drug Eruptions; Female; Formaldehyde; Inflammation; Mice; Mice, Inbred BALB C; Mice, Knockout; Nerve Growth Factors; RNA, Messenger; Time Factors; TRPV Cation Channels

2012
New models of experimental parotitis and parotid gland distension in rats.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 851

    Topics: Animals; Capsaicin; Catheterization; Disease Models, Animal; Freund's Adjuvant; Inflammation; Neurons; Pain Measurement; Parotid Gland; Parotitis; Physical Stimulation; Rats

2012
Increased central and peripheral inflammation and inflammatory hyperalgesia in Zucker rat model of leptin receptor deficiency and genetic obesity.
    Experimental physiology, 2012, Volume: 97, Issue:11

    Topics: Adiponectin; Animals; Capsaicin; Carrageenan; Down-Regulation; Edema; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Morphine; Nitric Oxide Synthase Type II; Nociception; Obesity; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Zucker; Receptors, Leptin; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha; Up-Regulation

2012
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature.
    Pharmacological research, 2012, Volume: 66, Issue:3

    Topics: Analgesics; Animals; Body Temperature; Bronchoconstriction; Capsaicin; Edema; Female; Hyperalgesia; Hypothermia; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Respiratory System; Sciatic Nerve; TRPV Cation Channels

2012
Role of C-fibers during acute and chronic stress on formalin-induced paw edema in rats.
    Indian journal of experimental biology, 2012, Volume: 50, Issue:9

    Topics: Animals; Capsaicin; Dexamethasone; Edema; Formaldehyde; Inflammation; Male; Nerve Fibers, Unmyelinated; Rats; Rats, Wistar; Stress, Physiological; Swimming

2012
Mechanisms underlying ectopic persistent tooth-pulp pain following pulpal inflammation.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Animals; Capsaicin; Carbocyanines; Citrates; Dental Pulp; Extracellular Signal-Regulated MAP Kinases; Freund's Adjuvant; Glial Fibrillary Acidic Protein; Inflammation; Male; Masseter Muscle; Models, Biological; Molar; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Satellite Cells, Skeletal Muscle; Stilbamidines; Toothache; Trigeminal Ganglion; TRPV Cation Channels

2013
A unique representation of heat allodynia in the human brain.
    Neuron, 2002, Jul-18, Volume: 35, Issue:2

    Topics: Adult; Afferent Pathways; Brain; Brain Mapping; Capsaicin; Cerebrovascular Circulation; Functional Laterality; Humans; Hyperalgesia; Inflammation; Male; Nerve Fibers; Nerve Fibers, Myelinated; Nociceptors; Pain Measurement; Pain Threshold; Skin; Tomography, Emission-Computed

2002
Upregulation of neurokinin-1 receptor expression in rat spinal cord by an N-terminal metabolite of substance P.
    The European journal of neuroscience, 2002, Volume: 16, Issue:2

    Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Ganglia, Spinal; Immunohistochemistry; Inflammation; Isomerism; Male; Pain; Peptide Fragments; Posterior Horn Cells; Presynaptic Terminals; Protein Precursors; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tachykinins; Up-Regulation

2002
Augmentation of allergic early-phase reaction by nerve growth factor.
    American journal of respiratory and critical care medicine, 2002, Sep-15, Volume: 166, Issue:6

    Topics: Acute-Phase Reaction; Allergens; Animals; Asthma; Capsaicin; Data Interpretation, Statistical; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypersensitivity; Immunoglobulin E; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nerve Growth Factor; Neuronal Plasticity; Promoter Regions, Genetic; Serotonin

2002
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1

    Topics: Algorithms; Animals; Anticonvulsants; Capsaicin; Carbamazepine; Dose-Response Relationship, Drug; Guinea Pigs; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptors, Drug; Sciatic Nerve

2003
Pharmacology of vagal afferent nerve activity in guinea pig airways.
    Pulmonary pharmacology & therapeutics, 2003, Volume: 16, Issue:1

    Topics: Animals; Capsaicin; Electrophysiology; Guinea Pigs; Inflammation; Lung; Neurons, Afferent; Organ Culture Techniques; Phenotype; Vagus Nerve

2003
Bone marrow transplantation reveals an essential synergy between neuronal and hemopoietic cell neurokinin production in pulmonary inflammation.
    The Journal of clinical investigation, 2003, Volume: 111, Issue:7

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Capsaicin; Enzyme-Linked Immunosorbent Assay; Gene Deletion; Gene Expression Regulation; Hematopoietic Stem Cells; Immune System; Inflammation; Ligands; Lung; Mice; Mice, Transgenic; Neurokinin A; Neurons; Protein Precursors; Respiration; Substance P; Tachykinins; Time Factors; Trachea

2003
State-dependent phosphorylation of epsilon-isozyme of protein kinase C in adult rat dorsal root ganglia after inflammation and nerve injury.
    Journal of neurochemistry, 2003, Volume: 85, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Carrageenan; Disease Models, Animal; Diterpenes; Freund's Adjuvant; Ganglia, Spinal; Hindlimb; Hyperalgesia; Inflammation; Ligation; Male; Neurons; Nociceptors; Pain; Pain Measurement; Peripheral Nervous System Diseases; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Drug

2003
N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflammatory and neuropath
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:1

    Topics: Analgesics; Animals; Ataxia; Capsaicin; Hyperalgesia; Inflammation; Male; Nerve Tissue; Pain; Pain Threshold; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Drug

2003
Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:1

    Topics: Administration, Inhalation; Animals; Apoptosis; Capsaicin; Cell Death; Cell Line; Cloning, Molecular; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Flow Cytometry; Humans; Indicators and Reagents; Inflammation; Interleukin-6; Lung; Male; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction

2003
SYM 2081, an agonist that desensitizes kainate receptors, attenuates capsaicin and inflammatory hyperalgesia.
    Brain research, 2003, May-30, Volume: 973, Issue:2

    Topics: Animals; Capsaicin; Carrageenan; Dose-Response Relationship, Drug; Drug Administration Routes; Glutamates; Hyperalgesia; Inflammation; Lower Extremity; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Kainic Acid

2003
Intradermal capsaicin inhibits lumbar dorsal horn neuronal responses to colorectal distention.
    Neuroreport, 2003, May-23, Volume: 14, Issue:7

    Topics: Action Potentials; Animals; Capsaicin; Colon; Inflammation; Injections, Intradermal; Lumbar Vertebrae; Male; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Rectum

2003
A study of the cough reflex in idiopathic pulmonary fibrosis.
    American journal of respiratory and critical care medicine, 2003, Oct-15, Volume: 168, Issue:8

    Topics: Aged; Anti-Inflammatory Agents; Bradykinin; Brain-Derived Neurotrophic Factor; Bronchial Provocation Tests; Capsaicin; Case-Control Studies; Cough; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Nerve Growth Factor; Neutrophils; Prednisolone; Pulmonary Fibrosis; Sputum; Substance P; Total Lung Capacity; Treatment Outcome

2003
Stimulation of spinal 5-HT(2A/2C) receptors potentiates the capsaicin-induced in vivo release of substance P-like immunoreactivity in the rat dorsal horn.
    Brain research, 2003, Oct-10, Volume: 987, Issue:1

    Topics: Animals; Capsaicin; Carrageenan; Inflammation; Male; Microdialysis; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists; Spinal Cord; Substance P

2003
Protein kinases regulate the phosphorylation of the GluR1 subunit of AMPA receptors of spinal cord in rats following noxious stimulation.
    Brain research. Molecular brain research, 2003, Oct-21, Volume: 118, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Inflammation; Male; Nociceptors; Pain; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine

2003
Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:9

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Enteric Nervous System; Inflammation; Mice; Neurons, Afferent; Neuropeptides; Oligopeptides; Piperidines; Quinuclidines; Receptor, PAR-2; Receptors, Neurokinin-1

2003
Regulation of peripheral inflammation by spinal adenosine: role of somatic afferent fibers.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: Adenosine; Animals; Capsaicin; Feedback; Inflammation; Injections, Spinal; Male; Nerve Fibers; Neurons, Afferent; Neuropeptides; Neutrophil Infiltration; Neutrophils; Oxidopamine; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Nerve Roots; Sympathectomy, Chemical; Sympatholytics

2003
Mechanosensitive duodenal afferents contribute to vagal modulation of inflammation in the rat.
    The Journal of physiology, 2004, Jan-01, Volume: 554, Issue:Pt 1

    Topics: Animals; Bradykinin; Capsaicin; Catheterization; Duodenum; Electric Stimulation; Fasting; Inflammation; Knee Joint; Male; Mechanoreceptors; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Vagotomy; Vagus Nerve

2004
Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin.
    Neuroscience, 2004, Volume: 123, Issue:2

    Topics: Animals; Arginine; Benzazepines; Bicuculline; Capsaicin; Foot; GABA Antagonists; Inflammation; Injections, Spinal; Laser-Doppler Flowmetry; Male; Pain; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Skin; Spinal Cord; Sympathectomy; Sympathetic Nervous System

2004
Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice.
    Neuroscience, 2004, Volume: 125, Issue:2

    Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Ear; Edema; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Neurokinin-1 Receptor Antagonists; Piperidines; Plant Extracts; Plant Oils; Quinuclidines; Receptors, Drug; Receptors, Neurokinin-1; Staining and Labeling; Time Factors; TRPV Cation Channels

2004
The analgesic effect induced by capsaicin is enhanced in inflammatory states.
    Life sciences, 2004, May-14, Volume: 74, Issue:26

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Disease Models, Animal; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Receptors, Drug; Time Factors

2004
Implantation of tumoral XC cells induces chronic, endothelin-dependent, thermal hyperalgesia in mice.
    Cellular and molecular neurobiology, 2004, Volume: 24, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Capsaicin; Cell Line, Transformed; Cell Line, Tumor; Chronic Disease; Endothelin Receptor Antagonists; Endothelins; Fibroblasts; Genetic Vectors; Hindlimb; Hyperalgesia; Inflammation; Male; Mice; Morphine; Neoplasm Regression, Spontaneous; Neoplasm Transplantation; Nociceptors; Oligopeptides; Pain Measurement; Peptides, Cyclic; Piperidines; Rats; Reaction Time; Receptors, Endothelin

2004
The effect of cutaneous mast cell degranulation on sensitivity to heat.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:7

    Topics: Adolescent; Adult; Axons; Capsaicin; Hot Temperature; Humans; Inflammation; Iontophoresis; Leukocytes; Male; Mast Cells; Norepinephrine; p-Methoxy-N-methylphenethylamine; Pain; Sensitivity and Specificity; Skin; Time Factors; Vasoconstrictor Agents; Vasodilator Agents

2004
Pro-nociceptive role of peripheral galanin in inflammatory pain.
    Pain, 2004, Volume: 110, Issue:1-2

    Topics: Action Potentials; Animals; Axons; Behavior, Animal; Capsaicin; Cell Count; Dose-Response Relationship, Drug; Drug Interactions; Galanin; Immunohistochemistry; In Vitro Techniques; Inflammation; Male; Microscopy, Electron; Pain; Pain Measurement; Peptide Fragments; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Receptor, Galanin, Type 2; Receptors, Drug; Skin; Substance P

2004
Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.
    British journal of pharmacology, 2004, Volume: 143, Issue:2

    Topics: Administration, Oral; Animals; Camphanes; Cannabidiol; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hyperalgesia; Inflammation; Italy; Male; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Drug; Rimonabant; Time Factors

2004
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-22, Volume: 24, Issue:38

    Topics: Androstadienes; Animals; Capsaicin; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Inflammation; Ion Channels; Male; Morpholines; Nerve Growth Factor; Neurons, Afferent; Pain Measurement; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Skin; TRPV Cation Channels; Wortmannin

2004
Regulation mechanisms of vanilloid receptors.
    Novartis Foundation symposium, 2004, Volume: 261

    Topics: Adenosine Triphosphate; Animals; Capsaicin; Hot Temperature; Humans; Inflammation; Mice; Models, Neurological; Neurons, Afferent; Nociceptors; Pain; Rats; Receptors, Drug; Receptors, Purinergic P2

2004
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes

2005
Small-dose capsaicin reduces systemic inflammatory responses in septic rats.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:5

    Topics: Animals; Antioxidants; Calcitonin Gene-Related Peptide; Capsaicin; Cecum; Female; Inflammation; Interleukin-10; Interleukin-6; Ligation; Lysosomes; Macrophages; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Superoxide Dismutase; Tissue Distribution; Tumor Necrosis Factor-alpha

2004
Estrogen and inflammation increase the excitability of rat temporomandibular joint afferent neurons.
    Journal of neurophysiology, 2005, Volume: 93, Issue:3

    Topics: Action Potentials; Analysis of Variance; Animals; Capsaicin; Carbocyanines; Cell Count; Cell Size; Cells, Cultured; Chi-Square Distribution; Electric Capacitance; Electric Stimulation; Estrogens; Female; Freund's Adjuvant; Glycoproteins; Immunohistochemistry; Inflammation; Lectins; Membrane Potentials; Neurofilament Proteins; Neurons, Afferent; Ovariectomy; Patch-Clamp Techniques; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Temporomandibular Joint; Trigeminal Ganglion; Versicans

2005
Neurokinins and inflammatory cell iNOS expression in guinea pigs with chronic allergic airway inflammation.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:4

    Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Bronchial Hyperreactivity; Capsaicin; Chronic Disease; Elasticity; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Inflammation; Lung; Male; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin

2005
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:1

    Topics: Acrylamides; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; CHO Cells; Cricetinae; Freund's Adjuvant; Ganglia, Spinal; Hot Temperature; Humans; Hyperalgesia; Inflammation; Motor Activity; Neurons; Pain Measurement; Patch-Clamp Techniques; Protons; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Drug; Transfection

2005
Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jan-26, Volume: 25, Issue:4

    Topics: Amygdala; Animals; Auditory Cortex; Behavior, Animal; Capsaicin; Conditioning, Classical; Excitatory Postsynaptic Potentials; Fear; Formaldehyde; GluK2 Kainate Receptor; Hot Temperature; Inflammation; Male; Memory; Mice; Mice, Knockout; Neuronal Plasticity; Pain; Reaction Time; Receptors, Kainic Acid

2005
Molecular mechanisms of trigeminal nociception and sensation of pungency.
    Chemical senses, 2005, Volume: 30 Suppl 1

    Topics: Animals; Capsaicin; Cell Line; Cloning, Molecular; Electrophysiology; Humans; Inflammation; Models, Biological; Models, Chemical; Rats; Temperature; Trigeminal Nerve; TRPC Cation Channels; TRPV Cation Channels

2005
A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Mar-22, Volume: 102, Issue:12

    Topics: Animals; Arachidonic Acids; Calcium Signaling; Capsaicin; Cell Line; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Endocannabinoids; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation; Inflammation Mediators; Ion Channel Gating; Ion Channels; Macrophage Inflammatory Proteins; Mice; Mice, Inbred BALB C; Neurons; Polyunsaturated Alkamides; Rats; Receptors, CCR1; Receptors, Chemokine; Transfection; TRPV Cation Channels

2005
Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw.
    European journal of pharmacology, 2005, Mar-28, Volume: 511, Issue:2-3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2005
Dopamine type 2 receptor expression and function in rodent sensory neurons projecting to the airways.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 289, Issue:1

    Topics: Airway Obstruction; Animals; Calcium Signaling; Capsaicin; Dopamine Agonists; Indoles; Inflammation; Male; Nodose Ganglion; Olfactory Receptor Neurons; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Drug; Trachea

2005
Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse.
    Pain, 2005, Volume: 115, Issue:1-2

    Topics: Animals; Capsaicin; Cells, Cultured; Freund's Adjuvant; Glycoproteins; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Ion Channels; Men; Mice; Mice, Inbred C57BL; Nociceptors; TRPV Cation Channels

2005
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Capsaicin; Carrageenan; Chronic Disease; Dose-Response Relationship, Drug; Edema; Formaldehyde; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Isoquinolines; Ligation; Male; Motor Activity; Osteoarthritis; Pain; Pain Measurement; Pain, Postoperative; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sciatic Nerve; Spinal Nerves; Urea

2005
Vasodilatation of human gingiva and neurogenic inflammation.
    Clinical hemorheology and microcirculation, 2005, Volume: 32, Issue:4

    Topics: Adult; Capsaicin; Dental Papilla; Female; Gingiva; Gingivitis; Humans; Inflammation; Male; Mouth Mucosa; Neurogenic Inflammation; Neurons; Periodontitis; Periodontium; Time Factors

2005
Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.
    Neuropharmacology, 2005, Volume: 48, Issue:8

    Topics: Animals; Binding, Competitive; Body Temperature; Camphanes; Cannabidiol; Capsaicin; Drug Interactions; Ear, External; Gastrointestinal Motility; Inflammation; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant

2005
Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats.
    Brain research, 2005, Jun-07, Volume: 1046, Issue:1-2

    Topics: Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Facial Pain; Inflammation; Jaw; Male; Muscle, Skeletal; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Valine

2005
Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanisms.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Aug-15, Volume: 175, Issue:4

    Topics: Acute Disease; Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Cell Death; Extravascular Lung Water; Inflammation; Lung; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Neutrophils; Oligopeptides; Peroxidase; Positive-Pressure Respiration; Receptor, PAR-2; Up-Regulation

2005
Mechanism by which peripheral galanin increases acute inflammatory pain.
    Brain research, 2005, Sep-21, Volume: 1056, Issue:2

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Functional Laterality; Galanin; Inflammation; Male; Naphthalenes; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Time Factors

2005
Dendritic cells do not transduce inflammatory stimuli via the capsaicin receptor TRPV1.
    FEBS letters, 2005, Sep-26, Volume: 579, Issue:23

    Topics: Animals; Bone Marrow Cells; Calcium; Capsaicin; Cells, Cultured; Dendritic Cells; Humans; Inflammation; Ion Channels; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Rats; Signal Transduction; Substance P; TRPV Cation Channels

2005
Airway inflammation and cough sensitivity in cough-variant asthma.
    Allergy, 2005, Volume: 60, Issue:11

    Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Capsaicin; Cell Count; Diagnosis, Differential; Female; Histamine; Humans; Inflammation; Interleukin-5; Male; Nitric Oxide; Sputum

2005
Induced sputum eosinophils, bronchial reactivity, and cough sensitivity in subjects with allergic rhinitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56 Suppl 4

    Topics: Acetylcholine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Capsaicin; Cough; Eosinophils; Female; Humans; Inflammation; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Spirometry; Sputum; Surveys and Questionnaires

2005
[The response of the blood proteins to ablation of the capsaicin-sensitive nerves].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2005, Volume: 91, Issue:7

    Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Capsaicin; Humans; Inflammation; Male; Neurons, Afferent; Rats; Rats, Wistar; Trauma, Nervous System

2005
TRPV1 desensitisation and endogenous vanilloid involvement in the enhanced analgesia induced by capsaicin in inflamed tissues.
    Brain research bulletin, 2005, Nov-30, Volume: 67, Issue:6

    Topics: Adjuvants, Immunologic; Analgesics; Animals; Capsaicin; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Pain; Pain Measurement; TRPV Cation Channels

2005
Analgesic effects of capsazepine and resiniferatoxin on bone cancer pain in mice.
    Neuroscience letters, 2006, Jan-23, Volume: 393, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Bone Neoplasms; Capsaicin; Cell Line; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Freund's Adjuvant; Functional Laterality; Inflammation; Mice; Mice, Inbred C3H; Osteosarcoma; Pain; Pain Measurement; Reaction Time; Time Factors

2006
Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Oct-26, Volume: 25, Issue:43

    Topics: Acid Sensing Ion Channels; Animals; Behavior, Animal; Blotting, Northern; Capsaicin; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Cricetinae; Ganglia, Spinal; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Inflammation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Nerve Tissue Proteins; Neurons; Oocytes; Pain Measurement; Patch-Clamp Techniques; Physical Stimulation; Protein Structure, Tertiary; Protein Subunits; Protons; Reaction Time; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Time Factors; Transfection; Xenopus

2005
Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
    Journal of neuroimmunology, 2006, Volume: 171, Issue:1-2

    Topics: Albumins; Analysis of Variance; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Glycoproteins; Immunohistochemistry; Inflammation; Injections, Intradermal; Iodine Isotopes; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peroxidase; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Skin; Substance P; Tachykinins; Time Factors; Tumor Necrosis Factor-alpha

2006
Neonatal chronic hind paw inflammation alters sensitization to intradermal capsaicin in adult rats: a behavioral and immunocytochemical study.
    The journal of pain, 2005, Volume: 6, Issue:12

    Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Capsaicin; Chronic Disease; Complex Regional Pain Syndromes; Critical Period, Psychological; Disease Models, Animal; Foot; Hyperalgesia; Immunohistochemistry; Inflammation; Male; Nerve Fibers, Unmyelinated; Neuronal Plasticity; Neurons, Afferent; Nociceptors; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Up-Regulation

2005
Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:3

    Topics: Arthritis, Rheumatoid; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; Cell Line, Tumor; Cells, Cultured; Chondrocalcinosis; Cytosol; Diterpenes; Hot Temperature; Humans; Inflammation; Nerve Tissue Proteins; Pyrimidinones; RNA, Messenger; Synovial Membrane; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2006
Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's anti-inflammatory effect.
    Neuroscience research, 2006, Volume: 55, Issue:2

    Topics: Adrenergic Agents; Animals; Anti-Inflammatory Agents; Bee Venoms; Capsaicin; Disease Models, Animal; Diterpenes; Drug Interactions; Functional Laterality; Gene Expression; Inflammation; Leukocytes; Locus Coeruleus; Mice; Mice, Inbred ICR; Norepinephrine; Oncogene Proteins v-fos; Oxidopamine; Sciatic Neuropathy; Zymosan

2006
Pivotal involvement of neurogenic mechanism in subcutaneous bee venom-induced inflammation and allodynia in unanesthetized conscious rats.
    Experimental neurology, 2006, Volume: 200, Issue:2

    Topics: Analysis of Variance; Animals; Bee Venoms; Behavior, Animal; Capsaicin; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Pain Measurement; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Rhizotomy; Sciatic Nerve; Touch; Wakefulness

2006
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:2

    Topics: Animals; Capsaicin; Citric Acid; Cough; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Diterpenes; Guinea Pigs; Indomethacin; Inflammation; Isoquinolines; Male; Neurons, Afferent; Protein Kinase C; Protein Kinase Inhibitors; Receptor, PAR-2; Saline Solution, Hypertonic; Sulfonamides; TRPV Cation Channels; Trypsin

2006
Analgesic activity of a non-peptide imidazolidinedione somatostatin agonist: in vitro and in vivo studies in rat.
    Pain, 2006, Volume: 124, Issue:1-2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Bradykinin; Capsaicin; Colforsin; Drug Interactions; Formaldehyde; Hot Temperature; Imidazolidines; In Vitro Techniques; Inflammation; Male; Nerve Fibers; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Skin; Somatostatin; Thionucleotides

2006
Role of the Na+-K+-2Cl- cotransporter in the development of capsaicin-induced neurogenic inflammation.
    Journal of neurophysiology, 2006, Volume: 95, Issue:6

    Topics: Animals; Bumetanide; Capsaicin; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Rats; Rats, Sprague-Dawley; Reflex; Sodium-Potassium-Chloride Symporters; Vasodilation

2006
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:1

    Topics: Action Potentials; Ammonia; Animals; Antioxidants; Blood Pressure; Capsaicin; Deferoxamine; Electrophysiology; Free Radical Scavengers; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Hydroxyl Radical; Inflammation; Laryngeal Muscles; Male; Neurons, Afferent; Pepsin A; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Thiourea

2006
The effects of pH on beta-endorphin and morphine inhibition of calcium transients in dorsal root ganglion neurons.
    The journal of pain, 2006, Volume: 7, Issue:7

    Topics: Analgesics, Opioid; Animals; beta-Endorphin; Calcium Signaling; Capsaicin; Cells, Cultured; Drug Interactions; Extracellular Fluid; Ganglia, Spinal; Hydrogen-Ion Concentration; Inflammation; Intracellular Fluid; Male; Morphine; Narcotic Antagonists; Neural Inhibition; Neurons, Afferent; Potassium; Rats; Rats, Wistar; Receptors, Opioid

2006
Selective inhibitors for phosphodiesterase 3 and 4 in antigen-induced increase of cough reflex sensitivity in guinea pigs.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:5

    Topics: Allergens; Animals; Antigens; Bronchoalveolar Lavage; Capsaicin; Cough; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Imidazoles; Inflammation; Injections, Intraperitoneal; Male; Nitriles; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pyridones; Reflex

2007
Blood protein reactions to ablation of capsaicin-sensitive neurons.
    Neuroscience and behavioral physiology, 2006, Volume: 36, Issue:7

    Topics: Albumins; Alpha-Globulins; Animals; Blood Proteins; Capsaicin; Denervation; gamma-Globulins; Inflammation; Male; Neurons, Afferent; Neurotoxicity Syndromes; Rats; Rats, Wistar; Zymosan

2006
Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats.
    The FEBS journal, 2006, Volume: 273, Issue:19

    Topics: Animals; Arachidonate 5-Lipoxygenase; Capsaicin; Carrageenan; Copper; Curcumin; Diet; Inflammation; Iron; Lipoproteins, LDL; Liver; Male; Neutrophils; Oxidation-Reduction; Rats; Rats, Wistar

2006
Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Animals; Biphenyl Compounds; Blotting, Western; Capsaicin; Cells, Cultured; Dinoprostone; Electrophysiology; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Hybridization; Inflammation; Injections, Spinal; Male; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Small Interfering

2006
Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity.
    The journal of pain, 2006, Volume: 7, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Capsaicin; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Glycine; Inflammation; Ion Channels; Male; Mice; Mice, Inbred ICR; Nociceptors; Oocytes; Pain; Patch-Clamp Techniques; Rats; Rats, Wistar; Sensory Receptor Cells; TRPV Cation Channels; Xenopus

2006
A role for adrenomedullin as a pain-related peptide in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Oct-24, Volume: 103, Issue:43

    Topics: Adrenomedullin; Animals; Behavior, Animal; Binding Sites; Calcitonin Gene-Related Peptide; Capsaicin; Enzyme Activation; Ganglia, Spinal; Inflammation; Injections, Spinal; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Nociceptors; Pain; Phosphotransferases; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Signal Transduction

2006
Impaired pain sensation in mice lacking prokineticin 2.
    Molecular pain, 2006, Nov-15, Volume: 2

    Topics: Animals; Behavior, Animal; Capsaicin; Ganglia, Spinal; Gastrointestinal Hormones; Hypesthesia; In Situ Hybridization; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuropeptides; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Reaction Time; Stimulation, Chemical; TRPV Cation Channels

2006
Sulfur-dioxide exposure increases TRPV1-mediated responses in nodose ganglia cells and augments cough in guinea pigs.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:6

    Topics: Air Pollutants; Animals; Anti-Inflammatory Agents; Capsaicin; Cough; Dexamethasone; Guinea Pigs; Inflammation; Leukocyte Count; Lung; Male; Neutrophils; Nodose Ganglion; Respiratory Function Tests; Sulfur Dioxide; TRPV Cation Channels

2007
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.
    European journal of pharmacology, 2007, Feb-05, Volume: 556, Issue:1-3

    Topics: Administration, Oral; Animals; Cannabidiol; Cannabinoid Receptor Antagonists; Cannabis; Capsaicin; Chronic Disease; Dinoprostone; Freund's Adjuvant; Hyperalgesia; Inflammation; Lipid Peroxides; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar; Sciatic Neuropathy; Tumor Necrosis Factor-alpha

2007
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes.
    Cell, 2006, Dec-15, Volume: 127, Issue:6

    Topics: Animals; Autoimmunity; Capsaicin; Diabetes Mellitus, Type 1; Female; Inflammation; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Inbred NOD; Neurons, Afferent; Substance P; T-Lymphocytes; TRPV Cation Channels

2006
Sex differences in the potency of kappa opioids and mixed-action opioids administered systemically and at the site of inflammation against capsaicin-induced hyperalgesia in rats.
    Psychopharmacology, 2007, Volume: 191, Issue:2

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Inflammation; Injections, Intraventricular; Injections, Subcutaneous; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Inbred F344; Receptors, Opioid; Sex Factors

2007
Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse.
    Regulatory peptides, 2007, Jun-07, Volume: 141, Issue:1-3

    Topics: Animals; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Capsaicin; Endotoxins; Enzyme-Linked Immunosorbent Assay; Female; Histocytochemistry; Inflammation; Interleukin-1beta; Lung; Mice; Mice, Inbred C57BL; Neurons, Afferent; Neuropeptides; Peroxidase; Radioimmunoassay; Somatostatin; Spectrophotometry; Substance P

2007
AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain.
    Brain research, 2007, Jun-04, Volume: 1152

    Topics: Animals; Arachidonic Acids; Capsaicin; Endocannabinoids; Immunohistochemistry; Indoles; Inflammation; Male; Pain; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Cord; TRPV Cation Channels

2007
Attenuated cold sensitivity in TRPM8 null mice.
    Neuron, 2007, May-03, Volume: 54, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Calcium; Capsaicin; Cells, Cultured; Cold Temperature; Ganglia, Spinal; Inflammation; Methanol; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons, Afferent; Pain Measurement; Pyrimidinones; Reaction Time; Thermosensing; TRPM Cation Channels

2007
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, May-15, Volume: 104, Issue:20

    Topics: Action Potentials; Analgesics; Aniline Compounds; Animals; Capsaicin; Evoked Potentials; Furans; Ganglia, Spinal; Humans; Inflammation; Kinetics; Male; Mononeuropathies; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurons; Pain; Pain Management; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sodium Channel Blockers; Sodium Channels

2007
Static magnetic field-induced anti-nociceptive effect and the involvement of capsaicin-sensitive sensory nerves in this mechanism.
    Life sciences, 2007, Jun-20, Volume: 81, Issue:2

    Topics: Analgesia; Animals; Capsaicin; Carrageenan; Chemoreceptor Cells; Diterpenes; Electromagnetic Fields; Formaldehyde; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred BALB C; Nerve Fibers; Neurons, Afferent; Pain Measurement; Postural Balance

2007
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
    The Journal of biological chemistry, 2007, Sep-07, Volume: 282, Issue:36

    Topics: Animals; Aprotinin; Calcium Signaling; Capsaicin; Edema; Enteropeptidase; Ganglia, Spinal; Granulocytes; Humans; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptor, PAR-2; Receptors, Proteinase-Activated; Receptors, Thrombin; Recombinant Proteins; Trypsin; Trypsin Inhibitors

2007
Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat.
    Peptides, 2007, Volume: 28, Issue:9

    Topics: Acute Disease; Animals; Capsaicin; Carrageenan; Diterpenes; Edema; Inflammation; Injections, Intraperitoneal; Male; Mass Spectrometry; Neurogenic Inflammation; Pituitary Adenylate Cyclase-Activating Polypeptide; Radioimmunoassay; Rats; Rats, Wistar; TRPV Cation Channels

2007
Targeted disruption of the galanin gene attenuates inflammatory responses in murine skin.
    Journal of molecular neuroscience : MN, 2008, Volume: 34, Issue:2

    Topics: Animals; Antipruritics; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Galanin; Gene Targeting; Hot Temperature; Humans; Inflammation; Mice; Mice, Knockout; Neurotransmitter Agents; Neutrophils; Skin; Substance P

2008
Effect of pressure stress applied to the airway on cough-reflex sensitivity in Guinea pigs.
    American journal of respiratory and critical care medicine, 2008, Mar-15, Volume: 177, Issue:6

    Topics: Animals; Biomechanical Phenomena; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Cough; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Hydroxyurea; Inflammation; Irritants; Male; Neutrophils; Reflex; Respiration, Artificial

2008
Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia.
    Molecular pain, 2008, Jan-16, Volume: 4

    Topics: Administration, Cutaneous; Animals; Behavior, Animal; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Edema; Electric Stimulation; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Inflammation; Male; Neurogenic Inflammation; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Sciatic Nerve; Time Factors; TRPV Cation Channels

2008
Reversal of pathological pain through specific spinal GABAA receptor subtypes.
    Nature, 2008, Jan-17, Volume: 451, Issue:7176

    Topics: Analgesics; Animals; Brain; Capsaicin; Chronic Disease; Diazepam; Disease Models, Animal; Fluorobenzenes; Formaldehyde; Ganglia, Spinal; Hot Temperature; Inflammation; Male; Mice; Neurons; Organ Specificity; Pain; Protein Isoforms; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Triazoles

2008
Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber).
    PLoS biology, 2008, Volume: 6, Issue:1

    Topics: Acids; Animals; Capsaicin; Hyperalgesia; Inflammation; Mole Rats; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells

2008
Changes in synaptic effectiveness of myelinated joint afferents during capsaicin-induced inflammation of the footpad in the anesthetized cat.
    Experimental brain research, 2008, Volume: 187, Issue:1

    Topics: Action Potentials; Afferent Pathways; Animals; Arthralgia; Capsaicin; Cats; Female; Foot; Inflammation; Joints; Male; Mechanoreceptors; Neural Conduction; Neural Inhibition; Neuronal Plasticity; Nociceptors; Proprioception; Sensory System Agents; Sensory Thresholds; Skin; Somatosensory Disorders; Synaptic Transmission; Time Factors

2008
Peripheral inflammation undermines the plasticity of the isolated spinal cord.
    Behavioral neuroscience, 2008, Volume: 122, Issue:1

    Topics: Analysis of Variance; Animals; Capsaicin; Conditioning, Psychological; Dose-Response Relationship, Drug; Electric Stimulation; Inflammation; Learning Disabilities; Male; Naltrexone; Narcotic Antagonists; Neuronal Plasticity; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord Injuries; Time Factors; Touch

2008
Inflammation-induced increase in evoked calcium transients in subpopulations of rat dorsal root ganglion neurons.
    Neuroscience, 2008, Apr-22, Volume: 153, Issue:1

    Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Capsaicin; Cell Size; Cells, Cultured; Fura-2; Ganglia, Spinal; Inflammation; Male; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Pain; Plant Lectins; Potassium; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2008
Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Capsaicin; Capsicum; Carrageenan; Cell Movement; Edema; Exudates and Transudates; Inflammation; Interleukin-1beta; L-Lactate Dehydrogenase; Leukocytes; Male; Mice; Mice, Inbred C57BL; Peritonitis; Phytotherapy; Plant Preparations; Pleurisy; Rats; Rats, Wistar; Serum Albumin, Bovine; Tumor Necrosis Factor-alpha

2008
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs.
    International immunopharmacology, 2008, Volume: 8, Issue:5

    Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cough; Eosinophils; Guinea Pigs; Histamine; Inflammation; Lidocaine; Lung; Male; Ovalbumin; Substance P

2008
[Peptidergic and sensory mechanisms, parasympathetic and sympathetic nerves].
    Lakartidningen, 1984, Dec-26, Volume: 81, Issue:52

    Topics: Brain Chemistry; Capsaicin; Humans; Immunochemistry; Inflammation; Muscle Contraction; Nerve Tissue Proteins; Neurons, Afferent; Parasympathetic Nervous System; Sympathetic Nervous System; Synaptic Transmission; Vasodilation

1984
Effects of capsaicin on inflammation and on the substance P content of nervous tissues in rats with adjuvant arthritis.
    Life sciences, 1983, Apr-18, Volume: 32, Issue:16

    Topics: Animals; Arthritis; Arthritis, Experimental; Capsaicin; Fatty Acids, Unsaturated; Inflammation; Kinetics; Male; Mycobacterium; Nervous System; Rats; Rats, Inbred Strains; Substance P

1983
Direct evidence for an axonal site of action of capsaicin.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 313, Issue:1

    Topics: Administration, Topical; Animals; Axons; Capsaicin; Fatty Acids, Unsaturated; Female; Inflammation; Male; Nociceptors; Rats

1980
Sensory denervation with capsaicin attenuates inflammation and nociception in arthritic rats.
    Neuroscience letters, 1995, Jul-07, Volume: 193, Issue:3

    Topics: Animals; Arthritis; Capsaicin; Inflammation; Male; Nociceptors; Pain; Rats; Rats, Wistar; Sensory Thresholds; Time Factors

1995
The 21st Meeting of the British Inflammation Research Society, "Inflammatory pain", King's College, London, 19th December, 1994.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:6

    Topics: Arthritis, Experimental; Asthma; Bronchial Hyperreactivity; Capsaicin; Humans; Inflammation; Nerve Growth Factors; Neurons, Afferent; Nitric Oxide Synthase; Pain; Receptors, Bradykinin; Spinal Cord; Up-Regulation

1995
The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule.
    Nature medicine, 1995, Volume: 1, Issue:8

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Immunoglobulin G; Inflammation; Nerve Growth Factors; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins

1995
A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Capsaicin; Electric Stimulation; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Morphine; Mucus; Nasal Mucosa; Pyrroles; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synapses; Thiophenes; Xylenes

1993
NK1 receptors mediate neurogenic inflammatory increase in blood flow in rat airways.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: Animals; Capsaicin; Inflammation; Male; Microspheres; Neurons, Afferent; Peptidyl-Dipeptidase A; Piperidines; Rats; Rats, Inbred F344; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Regional Blood Flow; Respiratory System; Respiratory Tract Diseases; Substance P; Tachykinins; Vasodilation

1993
Inhibition of neurogenic inflammation in the meninges by a non-peptide NK1 receptor antagonist, RP 67580.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Dura Mater; Guinea Pigs; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Meninges; Migraine Disorders; Rats; Rats, Wistar; Stereoisomerism; Substance P

1993
Sensitization of insensitive branches of C nociceptors in human skin.
    The Journal of physiology, 1994, Oct-15, Volume: 480 ( Pt 2)

    Topics: Adult; Capsaicin; Electric Stimulation; Electrophysiology; Humans; Hyperalgesia; Inflammation; Male; Mechanoreceptors; Mustard Plant; Nociceptors; Plant Extracts; Plant Oils; Skin

1994
Inflammation and hyperalgesia in rats neonatally treated with capsaicin: effects on two classes of nociceptive neurons in the superficial dorsal horn.
    Pain, 1994, Volume: 59, Issue:2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Electric Stimulation; Female; Freund's Adjuvant; Hyperalgesia; Immunohistochemistry; Inflammation; Microscopy, Electron; Nerve Fibers; Neurons, Afferent; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord

1994
Carrageenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment.
    Pain, 1994, Volume: 56, Issue:2

    Topics: Animals; Animals, Newborn; Capsaicin; Carrageenan; Denervation; Female; Foot; gamma-Aminobutyric Acid; Immunohistochemistry; Inflammation; Nerve Fibers; Neurons, Afferent; Nociceptors; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Tissue Fixation

1994
Effects of CGRP in different models of mouse ear inflammation.
    Life sciences, 1994, Volume: 54, Issue:8

    Topics: Analysis of Variance; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Cantharidin; Capsaicin; Croton Oil; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Inflammation; Male; Mice; Tetradecanoylphorbol Acetate

1994
Effects of capsaicin on the airway responses to inhaled endotoxin in the guinea pig.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capsaicin; Endotoxins; Escherichia coli; Glycopeptides; Guinea Pigs; Histamine; Inflammation; Lipopolysaccharides; Macrophages; Male; Neprilysin; Neutrophils; Premedication; Propranolol; Trachea

1994
Mechanisms of activation of the pituitary-adrenal axis by tissue injury in the rat.
    Psychoneuroendocrinology, 1994, Volume: 19, Issue:2

    Topics: Acute-Phase Reaction; Adrenocorticotropic Hormone; Afferent Pathways; Animals; Animals, Newborn; Arousal; Capsaicin; Corticosterone; Hypothalamo-Hypophyseal System; Inflammation; Interleukin-6; Male; Nociceptors; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Turpentine

1994
Capsaicin pretreatment increases inflammatory response to intratracheal instillation of endotoxin in rats.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Bronchoalveolar Lavage Fluid; Capsaicin; Drug Synergism; Inflammation; Instillation, Drug; Lipopolysaccharides; Lung; Male; Nerve Fibers; Neutrophils; Rats; Rats, Sprague-Dawley; Trachea; Tumor Necrosis Factor-alpha

1993
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Aerosols; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; Inflammation; Lung; Male; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pulmonary Circulation; Receptors, Neurokinin-2; Vascular Resistance

1993
Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: Aerosols; Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Indomethacin; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Stress, Mechanical; Trachea

1993
Vanilloids. 1. Analogs of capsaicin with antinociceptive and antiinflammatory activity.
    Journal of medicinal chemistry, 1993, Sep-03, Volume: 36, Issue:18

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Croton Oil; Homovanillic Acid; Hot Temperature; Inflammation; Male; Mice; Mice, Inbred ICR; Molecular Structure; Pain Measurement; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1993
Characterization of neurogenic inflammation in the airways of two highly inbred rat strains.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:6 Pt 1

    Topics: Animals; Benzamides; Blood Pressure; Bronchi; Capillary Permeability; Capsaicin; Cimetidine; Coloring Agents; Dose-Response Relationship, Drug; Evans Blue; Histamine Antagonists; Indoles; Inflammation; Isoindoles; Methysergide; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrilamine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Neurokinin-1; Serotonin; Serotonin Antagonists; Substance P; Trachea

1995
[Effect of blocking capsaicin-sensitive nerves on development of exudate reaction in immune response and aseptic inflammation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 120, Issue:10

    Topics: Animals; Capsaicin; Exudates and Transudates; Inflammation; Male; Mice; Mice, Inbred BALB C; Nerve Block; Neurons; Vaccines

1995
Inflammatory cellular influx follows capsaicin nasal challenge.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:4 Pt 1

    Topics: Adult; Capsaicin; Female; Humans; Hypersensitivity; Inflammation; Leukocyte Count; Leukocytes, Mononuclear; Male; Middle Aged; Nasal Mucosa; Neutrophils; Rhinitis

1996
Sensory denervation by neonatal capsaicin treatment exacerbates Mycoplasma pulmonis infection in rat airways.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Animals; Animals, Newborn; Capsaicin; Denervation; Epithelium; Inflammation; Lung Diseases; Male; Mucous Membrane; Mycoplasma Infections; Neovascularization, Pathologic; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P; Trachea

1996
The effect of intra-articular capsaicin on nerve fibres within the synovium of the rat knee joint.
    Journal of chemical neuroanatomy, 1996, Volume: 10, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Inflammation; Injections, Intra-Articular; Knee Joint; Leukocytes, Mononuclear; Male; Nerve Fibers; Nerve Tissue Proteins; Neuropeptide Y; Neutrophils; Rats; Rats, Wistar; Substance P; Synovial Membrane; Thiolester Hydrolases; Ubiquitin Thiolesterase

1996
Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo.
    The European respiratory journal, 1996, Volume: 9, Issue:3

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Antitussive Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inflammation; Male; Regression Analysis; Respiratory System; Smoke; Thiazoles; Thiazolidines

1996
Influence of inflammation or disconnection from peripheral target tissue on the capsaicin sensitivity of rat dorsal root ganglion sensory neurones.
    Neuroscience letters, 1996, Jan-19, Volume: 203, Issue:2

    Topics: Animals; Biological Transport; Calcium; Capsaicin; Cells, Cultured; Denervation; Drug Resistance; Ganglia, Spinal; Inflammation; Ion Channel Gating; Ion Channels; Nerve Growth Factors; Neurons, Afferent; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sciatic Nerve

1996
The vasodilator component of neurogenic inflammation is caused by a special subclass of heat-sensitive nociceptors in the skin of the pig.
    The Journal of physiology, 1996, Jul-15, Volume: 494 ( Pt 2)

    Topics: Animals; Axons; Capsaicin; Electric Stimulation; Hot Temperature; Humans; Inflammation; Mechanoreceptors; Nerve Fibers; Nociceptors; Regional Blood Flow; Saphenous Vein; Skin; Swine

1996
Role of C fibers in the inflammatory response to intratracheal lipopolysaccharide.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 1

    Topics: Animals; Capsaicin; Female; Inflammation; Lipopolysaccharides; Nerve Fibers; Pregnancy; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Trachea

1996
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:5

    Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P

1996
PACAP occurs in sensory nerve fibers and participates in ocular inflammation in the rabbit.
    Annals of the New York Academy of Sciences, 1996, Dec-26, Volume: 805

    Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Capsaicin; Ciliary Body; Eye; Eye Injuries; Inflammation; Iris; Nerve Fibers; Neurons, Afferent; Neuropeptides; Neurotransmitter Agents; Ocular Physiological Phenomena; Organ Specificity; Pituitary Adenylate Cyclase-Activating Polypeptide; Rabbits

1996
Dose-dependent protective effect of BPC 157 on capsaicin-induced rhinitis in rats.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1997, Volume: 254 Suppl 1

    Topics: Administration, Intranasal; Animals; Capsaicin; Cell Count; Cell Degranulation; Dose-Response Relationship, Drug; Inflammation; Injections, Intraperitoneal; Lymphocytes; Male; Mast Cells; Nasal Mucosa; Nasal Provocation Tests; Neutrophils; Peptide Fragments; Proteins; Rats; Rats, Wistar; Rhinitis; Sodium Chloride

1997
Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation.
    American journal of respiratory cell and molecular biology, 1997, Volume: 16, Issue:3

    Topics: Adenoviruses, Human; Animals; Capillary Permeability; Capsaicin; Dexamethasone; Ficusin; Gene Transfer Techniques; Genetic Vectors; Glucocorticoids; Hot Temperature; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Photosensitizing Agents; Piperidines; Protein Denaturation; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Respiratory System; Substance P; Ultraviolet Rays

1997
Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions.
    Neuroscience, 1997, Volume: 77, Issue:3

    Topics: Animals; Animals, Newborn; Capsaicin; Cerebral Cortex; Chymases; Denervation; Dura Mater; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine Antagonists; Inflammation; Male; Mast Cells; Methylhistamines; Nerve Fibers; Neurons, Afferent; Nippostrongylus; Piperidines; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Serine Endopeptidases; Strongylida Infections

1997
Ocular inflammation induced by electroconvulsive treatment: contribution of nitric oxide and neuropeptides mobilized from C-fibres.
    British journal of pharmacology, 1997, Volume: 120, Issue:8

    Topics: Animals; Aqueous Humor; Capsaicin; Electroconvulsive Therapy; Eye Diseases; Inflammation; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Receptors, Tachykinin; Substance P

1997
Effects of neurokinin depletion on airway inflammation induced by chronic antigen exposure.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:5

    Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Antigens; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; CD4 Lymphocyte Count; Edema; Elasticity; Guinea Pigs; Inflammation; Lung; Lung Compliance; Male; Ovalbumin; Tachykinins

1997
Plasma extravasation and neuropeptide release in human skin as measured by intradermal microdialysis.
    Neuroscience letters, 1997, Jul-18, Volume: 230, Issue:2

    Topics: Adult; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Forearm; Histamine; Humans; Inflammation; Iontophoresis; Microdialysis; Pain; Skin; Substance P; Time Factors

1997
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:9

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles

1997
Plasma protein extravasation induced in the rat dura mater by stimulation of the parasympathetic sphenopalatine ganglion.
    Experimental neurology, 1997, Volume: 147, Issue:2

    Topics: Acetylcholine; Afferent Pathways; Animals; Atropine; Axons; Blood Pressure; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Disease Models, Animal; Dura Mater; Electric Stimulation; Exudates and Transudates; Ganglia, Parasympathetic; Inflammation; Injections, Intra-Arterial; Male; Migraine Disorders; Neurons, Afferent; Parasympathetic Fibers, Postganglionic; Parasympathomimetics; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serum Albumin, Bovine; Substance P

1997
Inflammatory mediators at acidic pH activate capsaicin receptors in cultured sensory neurons from newborn rats.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Cells, Cultured; Coculture Techniques; Dinoprostone; Drug Synergism; Ganglia, Spinal; Hippocampus; Hydrogen-Ion Concentration; Inflammation; Ion Channel Gating; Neuroglia; Neurons, Afferent; Rats; Receptors, Drug; Serotonin; Stimulation, Chemical

1998
Role of sensory innervation and mast cells in neurogenic plasma protein exudation into the airway lumen.
    Respirology (Carlton, Vic.), 1997, Volume: 2, Issue:4

    Topics: Analysis of Variance; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Exudates and Transudates; Histamine; Inflammation; Mast Cells; Neuropeptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Substance P; Trachea; Vagus Nerve

1997
Neuropeptide regulation of proinflammatory cytokine responses.
    Journal of leukocyte biology, 1998, Volume: 63, Issue:5

    Topics: Animals; Capsaicin; Cytokines; Endotoxins; Female; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Spleen; Tachykinins; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

1998
Effects of neurotoxins and hindpaw inflammation on opioid receptor immunoreactivities in dorsal root ganglia.
    Neuroscience, 1998, Volume: 85, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Ganglia, Spinal; Hindlimb; Immunohistochemistry; Inflammation; Male; Neurotoxins; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Opioid; Spinal Cord; Tissue Distribution

1998
Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:7

    Topics: Abdominal Muscles; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Cyclooxygenase Inhibitors; Diclofenac; Formaldehyde; Inflammation; Male; Meloxicam; Mice; Morphine; Muscle Contraction; Pain; Pain Measurement; Reaction Time; Thiazines; Thiazoles

1998
Effects of airway inflammation on cough response in the guinea pig.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:5

    Topics: Animals; Antitussive Agents; Benzamides; Bronchoalveolar Lavage Fluid; Capsaicin; Codeine; Cough; Dipeptides; Female; Guinea Pigs; Indoles; Inflammation; Peptides, Cyclic; Piperidines; Quinuclidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Respiratory Hypersensitivity; Respiratory Tract Diseases

1998
Systemic anti-inflammatory effect induced by counter-irritation through a local release of somatostatin from nociceptors.
    British journal of pharmacology, 1998, Volume: 125, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Dextrans; Edema; Female; Inflammation; Rats; Rats, Wistar; Sensory Receptor Cells; Somatostatin

1998
A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: evidence for an endogenous capsaicin-like substance.
    Neuroscience, 1998, Volume: 86, Issue:2

    Topics: Animals; Capsaicin; Carrageenan; Functional Laterality; Hindlimb; Hyperalgesia; Inflammation; Male; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reflex; Spinal Cord

1998
VCAM-1 expression on human dermal microvascular endothelial cells is directly and specifically up-regulated by substance P.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-01, Volume: 162, Issue:3

    Topics: Capsaicin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Inflammation; Neuroimmunomodulation; RNA, Messenger; Skin; Substance P; T-Lymphocytes; Up-Regulation; Vascular Cell Adhesion Molecule-1

1999
The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Capsaicin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Excipients; Hindlimb; Hyperalgesia; Inflammation; Inflammation Mediators; Male; Nociceptors; Oxytocics; Pain; Pain Threshold; Rats; Rats, Wistar; Thionucleotides; Ultraviolet Rays

1999
Effects of the orally active non-peptide bradykinin B2 receptor antagonist, FR173657, on plasma extravasation in guinea pig airways.
    European journal of pharmacology, 1999, Feb-19, Volume: 367, Issue:2-3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Glycopeptides; Guinea Pigs; Inflammation; Male; Ovalbumin; Photometry; Protease Inhibitors; Quinolines; Respiratory System; Trachea

1999
The inflammatory reaction induced by formalin in the rat paw.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:3

    Topics: Anesthetics, Local; Animals; Blood Pressure; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Inflammation Mediators; Kininogens; Lidocaine; Male; Neuropeptides; Rats; Rats, Wistar; Serum Albumin; Time Factors

1999
Response properties of trigeminal brain stem neurons with input from dura mater encephali in the rat.
    Neuroscience, 1999, Volume: 90, Issue:2

    Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Dura Mater; Electric Stimulation; Histamine; Inflammation; Male; Mechanoreceptors; Microelectrodes; Neurons; Rats; Rats, Wistar; Serotonin; Trigeminal Nuclei; Trigeminal Nucleus, Spinal

1999
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.
    British journal of pharmacology, 1999, Volume: 126, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2

1999
Jaw electromyographic activity induced by the application of algesic chemicals to the rat tooth pulp.
    Pain, 1999, Volume: 80, Issue:3

    Topics: Animals; Bradykinin; Capsaicin; Dental Pulp; Electromyography; Evans Blue; Inflammation; Jaw; Male; Masseter Muscle; Mustard Plant; Naloxone; Narcotic Antagonists; Neutrophils; Pain; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley

1999
Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner.
    Neuroscience, 1999, Volume: 91, Issue:4

    Topics: Amidines; Animals; Capsaicin; Cells, Cultured; Densitometry; Fluorescent Dyes; Foot; Ganglia, Spinal; Inflammation; Male; Nerve Growth Factors; Neurons, Afferent; Rats; Rats, Sprague-Dawley

1999
Respiratory tract inflammation during the induction of chronic bronchitis in rats: role of C-fibres.
    The European respiratory journal, 1999, Volume: 14, Issue:1

    Topics: Animals; Animals, Newborn; Bronchi; Bronchitis; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Chronic Disease; Female; Inflammation; Macrophages, Alveolar; Maternal Exposure; Nasal Lavage Fluid; Nerve Fibers; Neutrophils; Pregnancy; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Sulfur Dioxide; Tachykinins

1999
Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats.
    Journal of neurophysiology, 1999, Volume: 82, Issue:5

    Topics: Animals; Bicuculline; Capsaicin; Femoral Nerve; Functional Laterality; Inflammation; Injections, Intradermal; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Reflex; Regional Blood Flow; Rhizotomy; Sciatic Nerve; Skin; Spinal Nerve Roots; Time Factors

1999
Impaired nociception and pain sensation in mice lacking the capsaicin receptor.
    Science (New York, N.Y.), 2000, Apr-14, Volume: 288, Issue:5464

    Topics: Animals; Body Temperature; Calcium; Capsaicin; Cells, Cultured; Diterpenes; Ganglia, Spinal; Gene Targeting; Hot Temperature; Hydrogen-Ion Concentration; Inflammation; Mice; Mice, Knockout; Nerve Fibers; Neurons; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Receptors, Drug; Spinal Cord; TRPV Cation Channels

2000
Interactions of inflammatory mediators and low pH not influenced by capsazepine in rat cutaneous nociceptors.
    Neuroreport, 2000, Apr-07, Volume: 11, Issue:5

    Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Drug Interactions; Ganglia, Spinal; Hydrogen-Ion Concentration; Inflammation; Inflammation Mediators; Male; Nerve Fibers; Nociceptors; Oxytocics; Protons; Rats; Rats, Wistar; Serotonin; Signal Transduction; Skin

2000
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia.
    Nature, 2000, May-11, Volume: 405, Issue:6783

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Behavior, Animal; Capsaicin; Carrageenan; Cells, Cultured; Electrophysiology; Endocannabinoids; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Targeting; Hot Temperature; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Polyunsaturated Alkamides; Receptors, Drug; Stem Cells; TRPV Cation Channels

2000
Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, May-23, Volume: 97, Issue:11

    Topics: Animals; Capsaicin; Cell Line; Cells, Cultured; Dinoprostone; Eicosanoids; Ganglia, Spinal; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Ion Channel Gating; Leukotriene B4; Leukotrienes; Ligands; Lipid Peroxides; Lipoxygenase; Molecular Structure; Neurons, Afferent; Prostaglandin D2; Prostaglandin H2; Prostaglandins H; Rats; Receptors, Drug; Structure-Activity Relationship

2000
Implications of oxidative stress and inflammatory process in the cytotoxicity of capsaicin in human endothelial cells: lack of DNA strand breakage.
    Toxicology, 2000, May-19, Volume: 147, Issue:1

    Topics: Capsaicin; Cells, Cultured; DNA Damage; DNA Fragmentation; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Protein Synthesis Inhibitors; Thiobarbituric Acid Reactive Substances

2000
Prostaglandin E(2)-mediated sensitization of rat sensory neurons is not altered by nerve growth factor.
    Neuroscience letters, 2000, Jun-16, Volume: 287, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic AMP; Dinoprostone; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley

2000
Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.
    Neuroscience, 2000, Volume: 98, Issue:2

    Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Colon; Cyclophosphamide; Cystitis; Female; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Mustard Plant; Nociceptors; Pain; Physical Stimulation; Plant Extracts; Plant Oils; Receptors, Neurokinin-1; Substance P; Urinary Bladder; Visceral Afferents

2000
Toward a new anti-inflammatory and analgesic agent.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-05, Volume: 97, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Bradykinin Receptor Antagonists; Capsaicin; Cyclooxygenase 2; Formaldehyde; Inflammation; Interleukin-1; Isoenzymes; Mice; Mice, Knockout; Pain; Prostaglandin-Endoperoxide Synthases; Receptor, Bradykinin B1; Receptors, Bradykinin; Receptors, Neurokinin-1; Shock, Septic

2000
Effects of topically applied capsaicin cream on neurogenic inflammation and thermal sensitivity in rats.
    Japanese journal of pharmacology, 2000, Volume: 82, Issue:2

    Topics: Administration, Topical; Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Pain Threshold; Rats; Rats, Sprague-Dawley; Substance P

2000
Systemic anti-inflammatory effect of somatostatin released from capsaicin-sensitive vagal and sciatic sensory fibres of the rat and guinea-pig.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Afferent Pathways; Animals; Anti-Inflammatory Agents; Blood Pressure; Capillary Permeability; Capsaicin; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; Female; Guanethidine; Guinea Pigs; Heart Rate; Hindlimb; Inflammation; Mustard Plant; Nerve Fibers; Pipecuronium; Plant Extracts; Plant Oils; Rats; Rats, Wistar; Sciatic Nerve; Skin; Somatostatin; Vagus Nerve

2000
Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo.
    Brain research, 2000, Jul-21, Volume: 871, Issue:2

    Topics: Animals; Calcium; Capsaicin; Cell Communication; Electric Stimulation; Guinea Pigs; Inflammation; Male; Membrane Potentials; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Substance P; Trigeminal Ganglion

2000
Responses of nerve fibres of the rat saphenous nerve neuroma to mechanical and chemical stimulation: an in vitro study.
    The Journal of physiology, 2000, Sep-01, Volume: 527 Pt 2

    Topics: Animals; Capsaicin; Electrophysiology; Hydrogen-Ion Concentration; Hypertonic Solutions; Inflammation; Nerve Endings; Nerve Fibers; Nerve Regeneration; Neural Conduction; Neuroma; Nociceptors; Physical Stimulation; Rats; Stimulation, Chemical; Tachyphylaxis

2000
Nociceptive neuroendocrine negative feedback control of neurogenic inflammation activated by capsaicin in the rat paw: role of the adrenal medulla.
    The Journal of physiology, 2000, Sep-15, Volume: 527 Pt 3

    Topics: Adrenal Medulla; Animals; Bradykinin; Capillary Permeability; Capsaicin; Denervation; Electric Stimulation; Feedback; Hindlimb; Hypothalamo-Hypophyseal System; Inflammation; Joints; Male; Neurons, Afferent; Neurosecretory Systems; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Synovial Fluid; Vagotomy

2000
Capsaicin inhibits platelet-activating factor-induced cytosolic Ca2+ rise and superoxide production.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Oct-01, Volume: 165, Issue:7

    Topics: Apoptosis; Biological Transport; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Capsaicin; Cytosol; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Inflammation; Platelet Activating Factor; Superoxides; Thapsigargin; Type C Phospholipases; Up-Regulation

2000
Antinociceptive activity of ricinoleic acid, a capsaicin-like compound devoid of pungent properties.
    European journal of pharmacology, 2000, Oct-27, Volume: 407, Issue:1-2

    Topics: Administration, Topical; Animals; Capsaicin; Carrageenan; Conjunctiva; Guinea Pigs; Hindlimb; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Ricinoleic Acids

2000
Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor.
    Nature, 2001, Jan-25, Volume: 409, Issue:6819

    Topics: Animals; Capsaicin; Gene Targeting; Inflammation; Male; Mice; Mice, Inbred BALB C; Mutagenesis; Pain; Pain Threshold; Plasma; Receptors, Neuropeptide Y; Substance P

2001
Development and sequels of intestinal inflammation in nematode-infected rats: role of mast cells and capsaicin-sensitive afferents.
    Neuroimmunomodulation, 2000, Volume: 8, Issue:4

    Topics: Animals; Capsaicin; Cell Count; Inflammation; Intestine, Small; Ketotifen; Mast Cells; Neurons, Afferent; Nippostrongylus; Peroxidase; Rats; Strongylida Infections

2000
Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity.
    Journal of neurochemistry, 2001, Volume: 76, Issue:6

    Topics: Afferent Pathways; Animals; Axonal Transport; Capsaicin; Colchicine; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Inflammation; Male; Nerve Endings; Oligodeoxyribonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sciatic Nerve; Transcription, Genetic

2001
Characterization of increased cough sensitivity after antigen challenge in guinea pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:3

    Topics: Allergens; Animals; Antigens; Bronchial Provocation Tests; Capsaicin; Cough; Eosinophils; Guinea Pigs; Hypersensitivity; Inflammation

2001
Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice.
    Nature neuroscience, 2001, Volume: 4, Issue:4

    Topics: Acetic Acid; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Fixatives; Formaldehyde; Ganglionic Stimulants; Inflammation; Magnesium Sulfate; Mice; Mice, Transgenic; Morphine; Naloxone; Narcotic Antagonists; Nicotine; Opioid-Related Disorders; Pain; Substance Withdrawal Syndrome

2001
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine.
    British journal of pharmacology, 2001, Volume: 133, Issue:1

    Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Hexamethonium; Inflammation; Knee Joint; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nicotine; Nociceptors; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid; Sciatic Nerve; Time Factors

2001
Role of calcitonin gene-related peptide and kinins in post-ischemic intestinal reperfusion.
    Peptides, 2001, Volume: 22, Issue:6

    Topics: Animals; Bradykinin Receptor Antagonists; Calcitonin Gene-Related Peptide; Capsaicin; Duodenum; Inflammation; Intestinal Mucosa; Ischemia; Kinins; Male; Mesenteric Arteries; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Reperfusion; Reperfusion Injury; Tachykinins; Time Factors

2001
Role of capsaicin-sensitive afferents in fever and cytokine responses during systemic and local inflammation in rats.
    Neuroimmunomodulation, 2001, Volume: 9, Issue:1

    Topics: Afferent Pathways; Animals; Animals, Newborn; Atrophy; Capsaicin; Cytokines; Denervation; Exploratory Behavior; Fever; Foot; Freund's Adjuvant; Inflammation; Injections, Intraperitoneal; Interleukin-6; Lipopolysaccharides; Lung; Neurons, Afferent; Nociceptors; Peritonitis; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Urinary Bladder

2001
Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jul-15, Volume: 21, Issue:14

    Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Capsaicin; Cells, Cultured; Chemokines; Fluorescent Dyes; Ganglia, Spinal; HIV Envelope Protein gp120; Hyperalgesia; Inflammation; Intracellular Fluid; Male; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, CCR4; Receptors, Chemokine; Receptors, CXCR4; RNA, Messenger; Substance P

2001
Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blepharitis; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Cells, Cultured; Drug Synergism; Female; Ganglia, Spinal; Guinea Pigs; Inflammation; Lectins; Male; Neurokinin A; Neurons; Plant Extracts; Plant Lectins; Rats; Ricinoleic Acids; Seeds; Substance P

2001
NMDA or non-NMDA receptor antagonists attenuate increased Fos expression in spinal dorsal horn GABAergic neurons after intradermal injection of capsaicin in rats.
    Neuroscience, 2001, Volume: 106, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blotting, Western; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Functional Laterality; gamma-Aminobutyric Acid; Inflammation; Injections, Intradermal; Interneurons; Male; Membrane Potentials; Neural Conduction; Neural Inhibition; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Up-Regulation

2001
Nitric oxide synthase in spinal cord central sensitization following intradermal injection of capsaicin.
    Pain, 2001, Volume: 94, Issue:1

    Topics: Animals; Capsaicin; Enzyme Inhibitors; Inflammation; Injections, Intradermal; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pain Measurement; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord

2001
Effects of PGE(2) on neurons from rat dorsal root ganglia in intact and adjuvant-inflamed rats: role of NGF on PGE(2)-induced depolarization.
    Neuroscience research, 2001, Volume: 41, Issue:4

    Topics: Action Potentials; Animals; Arthritis, Experimental; Bradykinin; Capsaicin; Cells, Cultured; Dinoprostone; Freund's Adjuvant; Ganglia, Spinal; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Rats; Rats, Wistar; Sensory Thresholds; Tachyphylaxis

2001
Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones.
    Neuroscience letters, 2002, Jan-14, Volume: 317, Issue:3

    Topics: Action Potentials; Animals; Capsaicin; Cells, Cultured; Cold Temperature; Cryotherapy; Ganglia, Spinal; Hypothermia, Induced; Inflammation; Neurons, Afferent; Nociceptors; Pain; Pain Management; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Drug; TRPV Cation Channels

2002
Attenuation of thermal nociception and hyperalgesia by VR1 blockers.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Feb-19, Volume: 99, Issue:4

    Topics: Animals; Calcium; Capsaicin; Dose-Response Relationship, Drug; Electrophysiology; Glycine; Hot Temperature; Hyperalgesia; Inflammation; Knee; Male; Mice; Mice, Inbred ICR; Mustard Plant; Neurons; Pain; Pain Threshold; Peptoids; Plant Extracts; Plant Oils; Rats; Rats, Wistar; Receptors, Drug; Recombinant Proteins; Stress, Mechanical; Time Factors; Xenopus

2002
Nociceptive behaviour induced by dental application of irritants to rat incisors: a new model for tooth inflammatory pain.
    European journal of pain (London, England), 2002, Volume: 6, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Capsaicin; Crowns; Cyclooxygenase Inhibitors; Dental Pulp Cavity; Disease Models, Animal; Drug Interactions; Female; Formaldehyde; Gingiva; Inflammation; Male; Meloxicam; Morphine; Naloxone; Narcotic Antagonists; Nerve Fibers; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles; Toothache

2002
Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs.
    European journal of pharmacology, 2002, Mar-29, Volume: 439, Issue:1-3

    Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cell Count; Cyclohexylamines; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Indoles; Inflammation; Macrophages; Male; Neurokinin A; Peptides, Cyclic; Receptors, Tachykinin; Substance P; Tachykinins; Time Factors; Vasodilator Agents

2002
Capsaicin-sensitive nerve fibres induce epithelial cell proliferation, inflammatory cell immigration and transforming growth factor-alpha expression in the rat colonic mucosa in vivo.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:4

    Topics: Animals; Blotting, Western; Bromodeoxyuridine; Calcitonin Gene-Related Peptide; Capsaicin; Cell Division; Colon; Denervation; Goblet Cells; Immunohistochemistry; Inflammation; Intestinal Mucosa; Male; Nerve Fibers; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Transforming Growth Factor alpha

2002
Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats.
    Brain research, 2002, May-10, Volume: 935, Issue:1-2

    Topics: Action Potentials; Afferent Pathways; Animals; Capsaicin; Carrageenan; Dose-Response Relationship, Drug; Inflammation; Injections, Spinal; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neural Inhibition; Nociceptors; Pain; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Drug

2002
Stimulation of deep somatic tissue with capsaicin produces long-lasting mechanical allodynia and heat hypoalgesia that depends on early activation of the cAMP pathway.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jul-01, Volume: 22, Issue:13

    Topics: Adenylyl Cyclase Inhibitors; Animals; Behavior, Animal; Capsaicin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hot Temperature; Inflammation; Injections; Joints; Kinetics; Male; Muscles; Organ Specificity; Pain; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Skin; Stress, Mechanical

2002
A study of chemically induced acute inflammation in the skin of the rat.
    Quarterly journal of experimental physiology and cognate medical sciences, 1977, Volume: 62, Issue:2

    Topics: Animals; Benzene; Capsaicin; Cell Count; Ear; Edema; Inflammation; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Skin; Sympathetic Nervous System

1977
Delta- and kappa-opioid agonists inhibit plasma extravasation induced by bradykinin in the knee joint of the rat.
    Neuroscience, 1992, Volume: 49, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Bradykinin; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Inflammation; Joints; Male; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa

1992
Immunoneutralization studies with calcitonin gene-related peptide.
    Annals of the New York Academy of Sciences, 1992, Jun-30, Volume: 657

    Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Emptying; Gastric Mucosa; Humans; Immune Sera; Immunization; Inflammation; Peptide Fragments; Rats; Rats, Inbred Strains; RNA, Messenger; Somatostatin

1992
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
    The British journal of dermatology, 1992, Volume: 126, Issue:2

    Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation

1992
Neonatal capsaicin treatment attenuates spinal Fos activation and dynorphin gene expression following peripheral tissue inflammation and hyperalgesia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:5

    Topics: Animals; Animals, Newborn; Capsaicin; Dynorphins; Enkephalins; Female; Foot Diseases; Gene Expression; Hyperalgesia; Inflammation; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Spinal Cord; Substance P

1992
Substance P-immunoreactive sensory axons in the rat respiratory tract: a quantitative study of their distribution and role in neurogenic inflammation.
    The Journal of comparative neurology, 1992, May-22, Volume: 319, Issue:4

    Topics: Animals; Arterioles; Axons; Bronchi; Capsaicin; Ganglia; Histocytochemistry; Inflammation; Male; Muscle, Smooth, Vascular; Neurons, Afferent; Rats; Rats, Inbred F344; Respiratory System; Substance P; Trachea; Vagotomy; Venules

1992
Evidence for an increase in the release of CGRP from sensory nerves during inflammation.
    Annals of the New York Academy of Sciences, 1992, Jun-30, Volume: 657

    Topics: Animals; Axonal Transport; Calcitonin Gene-Related Peptide; Capsaicin; Freund's Adjuvant; Hindlimb; Inflammation; Neurons, Afferent; Potassium; Rats; Sciatic Nerve; Skin; Spinal Cord; Time Factors

1992
Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation.
    Brain research, 1992, Jun-05, Volume: 582, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Edema; In Vitro Techniques; Inflammation; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P

1992
The quantitative contribution of nitric oxide and sensory nerves to bradykinin-induced inflammation in rat skin microvasculature.
    Brain research, 1992, Aug-28, Volume: 589, Issue:1

    Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Bradykinin; Capsaicin; Female; Inflammation; Male; Microcirculation; Molecular Sequence Data; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Stereoisomerism

1992
The partial inhibition of inflammatory responses induced by capsaicin using the Fab fragment of a selective calcitonin gene-related peptide antiserum in rabbit skin.
    Neuroscience, 1992, Volume: 48, Issue:4

    Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Edema; Immune Sera; Immunoglobulin Fab Fragments; Immunoglobulin G; Inflammation; Male; Rabbits; Skin

1992
Effect of synthetic tachykinin analogues on airway microvascular leakage in rats and guinea-pigs: evidence for the involvement of NK-1 receptors.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:4

    Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Guinea Pigs; Inflammation; Male; Microcirculation; Neuropeptides; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory System; Serotonin; Tachykinins

1991
Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antibodies; Capsaicin; Central Nervous System; Corticotropin-Releasing Hormone; Denervation; Eating; Fever; Flurbiprofen; Inflammation; Injections, Intramuscular; Kinetics; Male; Oxygen Consumption; Peripheral Nerves; Propranolol; Rats; Rats, Inbred Strains; Turpentine

1991
A bradykinin (BK)1 receptor antagonist blocks capsaicin-induced ear inflammation in mice.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: Animals; Bradykinin; Capsaicin; Ear, External; Edema; Inflammation; Male; Mice; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P

1990
Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:6

    Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Glycopeptides; In Vitro Techniques; Inflammation; Male; Neurons, Afferent; Neuropeptides; Rats; Rats, Inbred F344; Saline Solution, Hypertonic; Substance P; Trachea

1990
Capsaicin pretreatment modifies hydrogen sulphide-induced pulmonary injury in rats.
    Toxicologic pathology, 1990, Volume: 18, Issue:2

    Topics: Animals; Capsaicin; Hydrogen Sulfide; Inflammation; Lung; Lung Diseases; Male; Microscopy, Electron, Scanning; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P

1990
Serotonin modulates substance P-induced plasma extravasation and vasodilatation in rat skin by an action through capsaicin-sensitive primary afferent nerves.
    Brain research, 1990, Sep-17, Volume: 527, Issue:2

    Topics: Afferent Pathways; Animals; Blister; Capillary Permeability; Capsaicin; Inflammation; Male; Plasma; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin; Skin; Substance P; Time Factors; Vasodilation

1990
Modulation of a peripheral inflammatory response to substance P by locally administered opioid receptor agonists.
    Neuropeptides, 1990, Volume: 17, Issue:1

    Topics: Administration, Topical; Amino Acid Sequence; Animals; Blister; Capillary Permeability; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Inflammation; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Perfusion; Peripheral Nerves; Rats; Skin; Substance P; Vasodilation

1990
Inflammatory responses induced by substance P in rat paw.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Female; Histamine Release; Inflammation; Male; Rats; Rats, Inbred Strains; Substance P

1990
Neurogenic inflammation induced by capsaicin in patients with psoriasis.
    Acta dermato-venereologica, 1991, Volume: 71, Issue:1

    Topics: Administration, Cutaneous; Adult; Age Factors; Capsaicin; Dose-Response Relationship, Drug; Erythema; Forearm; Humans; Inflammation; Psoriasis; Scleroderma, Systemic; Skin; Substance P

1991
Mechanical irritation induces neurogenic inflammation in the rat urethra.
    The Journal of urology, 1991, Volume: 146, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglionectomy; Inflammation; Neurons, Afferent; Rats; Rats, Inbred Strains; Stress, Mechanical; Substance P; Urethra; Urethritis; Urinary Catheterization

1991
Potent anti-inflammatory action of calcitonin gene-related peptide.
    Biochemical and biophysical research communications, 1991, Nov-14, Volume: 180, Issue:3

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Cricetinae; Edema; Female; Histamine; Humans; Inflammation; Leukotriene B4; Male; Middle Aged; Mouth Mucosa; Rats; Serotonin; Skin; Skin Physiological Phenomena; Substance P

1991
Involvement of substance P in hyperalgesia induced by intrathecal galanin.
    Neuroscience research, 1991, Volume: 11, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Behavior, Animal; Capsaicin; Carrageenan; Galanin; Guinea Pigs; Ileum; In Vitro Techniques; Inflammation; Injections, Spinal; Male; Muscle, Smooth; Neurokinin A; Nociceptors; Pain; Peptides; Rats; Rats, Inbred Strains; Substance P

1991
Neurogenic component of different models of acute inflammation in the rat knee joint.
    Annals of the rheumatic diseases, 1991, Volume: 50, Issue:11

    Topics: Animals; Capsaicin; Carrageenan; Disease Models, Animal; Formaldehyde; Hindlimb; Inflammation; Joints; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Substance P; Uric Acid

1991
Ruthenium red and capsaicin induce a neurogenic inflammatory response in the rabbit eye: effects of omega-conotoxin GVIA and tetrodotoxin.
    European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3

    Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Capsaicin; Eye; Female; Inflammation; Intraocular Pressure; Male; Miosis; Neurokinin A; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Rabbits; Ruthenium Red; Substance P; Tetrodotoxin

1991
Trigeminal sensory fiber stimulation induces morphological changes reflecting secretion in rat dura mater mast cells.
    Neuroscience, 1991, Volume: 44, Issue:1

    Topics: Animals; Capsaicin; Cytoplasmic Granules; Dura Mater; Electric Stimulation; Humans; Inflammation; Male; Mast Cells; Neurons, Afferent; Rats; Rats, Inbred Strains; Tongue; Trigeminal Ganglion; Trigeminal Nerve; Vascular Headaches

1991
Systemic capsaicin and olvanil reduce the acute algogenic and the late inflammatory phase following formalin injection into rodent paw.
    Pain, 1991, Volume: 47, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Electrophysiology; Foot; Formaldehyde; Indomethacin; Inflammation; Mice; Morphine; Neurons; Pain; Spinal Cord

1991
The effect of neonatal treatment with capsaicin on focal arteriolar insudation.
    Microvascular research, 1991, Volume: 42, Issue:3

    Topics: Animals; Animals, Newborn; Arterioles; Body Weight; Capsaicin; Dilatation, Pathologic; Focal Infection; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains

1991
Further behavioral evidence that colorectal distension is a 'noxious' visceral stimulus in rats.
    Neuroscience letters, 1991, Sep-30, Volume: 131, Issue:1

    Topics: Animals; Avoidance Learning; Capsaicin; Colon; Inflammation; Male; Morphine; Motor Activity; Muscle Contraction; Muscle, Smooth; Pain; Rats; Rats, Inbred Strains; Rectum; Turpentine

1991
Biosynthesis and release of tachykinins from rat sensory neurons in culture.
    Journal of neuroscience research, 1991, Volume: 30, Issue:2

    Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Chromatography, High Pressure Liquid; Ganglia, Spinal; Inflammation; Neurons, Afferent; Neuropeptides; Nifedipine; Pain; Potassium; Radioimmunoassay; Rats; RNA, Messenger; Tachykinins; Trigeminal Ganglion

1991
Neurogenic inflammation of the rat trachea: fate of neutrophils that adhere to venules.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 69, Issue:6

    Topics: Analysis of Variance; Animals; Capsaicin; Cell Adhesion; Chemotaxis, Leukocyte; Female; Glycopeptides; Inflammation; Muscle, Smooth; Neutrophils; Peroxidase; Rats; Regression Analysis; Trachea; Vagus Nerve; Venules

1990
Mycoplasma pulmonis infections cause long-lasting potentiation of neurogenic inflammation in the respiratory tract of the rat.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:3

    Topics: Ammonia; Animals; Antigens, Bacterial; Capillary Permeability; Capsaicin; Epithelium; Inflammation; Lymphoid Tissue; Microscopy, Electron; Mycoplasma; Nervous System; Pneumonia, Mycoplasma; Rats; Trachea

1991
Involvement of capsaicin-sensitive neurones in hyperalgesia and enhanced opioid antinociception in inflammation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:6

    Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Freund's Adjuvant; Hyperalgesia; Inflammation; Injections, Subcutaneous; Male; Morphine; Narcotics; Neurons; Nociceptors; Pressure; Rats; Rats, Inbred Strains; Time Factors; Vasodilation

1990
Denervation-induced inflammation in the rat.
    Neuroscience letters, 1990, Oct-30, Volume: 119, Issue:1

    Topics: Animals; Bupivacaine; Capsaicin; Denervation; Electric Stimulation; Foot; Hindlimb; Inflammation; Male; Peripheral Nerves; Rats; Sciatic Nerve

1990
Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345.
    Agents and actions, 1990, Volume: 31, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Capsaicin; Carrageenan; Cell Movement; Edema; Guinea Pigs; Inflammation; Leukocytes; Male; Mice; Otitis; Platelet Aggregation Inhibitors; Pleurisy; Rats; Rats, Inbred Strains; Vanillic Acid

1990
Neurogenic inflammation, vascular permeability, and mast cells. Capsaicin desensitization fails to influence IgE-anti-DNP induced vascular permeability in rat airways.
    The American review of respiratory disease, 1990, Volume: 141, Issue:2

    Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Desensitization, Immunologic; Dinitrophenols; Immunization, Passive; Immunoglobulin E; Inflammation; Male; Mast Cells; Rats; Rats, Inbred Strains; Respiratory System; Respiratory Tract Diseases; Skin; Skin Tests; Specific Pathogen-Free Organisms; Trachea

1990
Motor and inflammatory effect of hyperosmolar solutions on the rat urinary bladder in relation to capsaicin-sensitive sensory nerves.
    General pharmacology, 1990, Volume: 21, Issue:1

    Topics: Animals; Blood Proteins; Capsaicin; Ganglionectomy; Hypertonic Solutions; In Vitro Techniques; Inflammation; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Inbred Strains; Urinary Bladder; Urination

1990
The effect of substance P on the regional lymph node antibody response to antigenic stimulation in capsaicin-pretreated rats.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Nov-15, Volume: 139, Issue:10

    Topics: Animals; Animals, Newborn; Antibody Formation; Antigens; Capsaicin; Inflammation; Injections, Subcutaneous; Leukocyte Count; Lymph Nodes; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P

1987
Substance P induced hydrolysis of inositol phospholipids in rat skin in an in vivo model of inflammation.
    Neuropeptides, 1989, Volume: 13, Issue:3

    Topics: Animals; Blister; Capillary Permeability; Capsaicin; Histamine; Hydrolysis; Inflammation; Phosphatidylinositols; Pyrilamine; Rats; Skin; Substance P

1989
Inhibition of carrageenan induced inflammation in the rat knee joint by substance P antagonist.
    Annals of the rheumatic diseases, 1989, Volume: 48, Issue:11

    Topics: Animals; Capsaicin; Carrageenan; Hindlimb; Inflammation; Joints; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Synovitis

1989
The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat.
    Neuroscience, 1989, Volume: 32, Issue:3

    Topics: Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Hindlimb; Immune Sera; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Vasodilation

1989
Participation of substance P in inflammatory responses.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Animals; Capsaicin; Dactinomycin; Denervation; Dexamethasone; Edema; Hot Temperature; Inflammation; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Nerves; Substance P

1989
Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper.
    Neuroscience, 1989, Volume: 30, Issue:2

    Topics: Animals; Capsaicin; Diterpenes; Female; Hypothermia; Inflammation; Pain; Rats; Rats, Inbred Strains

1989
Involvement of capsaicin-sensitive afferent nerve fibres in serotonin-induced plasma extravasation and vasodilatation in rat skin.
    Neuroscience letters, 1989, Sep-25, Volume: 104, Issue:1-2

    Topics: Animals; Animals, Newborn; Capsaicin; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Serotonin; Skin; Vasodilation

1989
Antidromic vasodilatation and neurogenic inflammation.
    Agents and actions, 1988, Volume: 23, Issue:1-2

    Topics: Animals; Capsaicin; Efferent Pathways; Electric Stimulation; Female; Humans; Inflammation; Male; Nerve Endings; Nociceptors; Rats; Rheology; Skin; Spinal Nerve Roots; Vasodilation

1988
The effects of capsaicin denervation on leucocyte and complement components of the inflammatory response.
    Clinical and experimental neurology, 1987, Volume: 24

    Topics: Animals; Capsaicin; Complement Hemolytic Activity Assay; Complement System Proteins; Female; Immune System; Inflammation; Leukocytes; Rats; Rats, Inbred Strains

1987
Neurogenically mediated plasma extravasation in dura mater: effect of ergot alkaloids. A possible mechanism of action in vascular headache.
    Cephalalgia : an international journal of headache, 1988, Volume: 8, Issue:2

    Topics: Animals; Capillary Permeability; Capsaicin; Dura Mater; Electric Stimulation; Ergot Alkaloids; Guinea Pigs; Inflammation; Nerve Fibers; Plasma; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Vascular Headaches

1988
Effect of capsaicin on bronchial reactivity and inflammation in sensitized adult rats.
    International archives of allergy and applied immunology, 1987, Volume: 82, Issue:3-4

    Topics: Animals; Antibodies; Capsaicin; Histocompatibility Antigens Class II; Immunization; Inflammation; Neuropeptides; Ovalbumin; Rats; Rats, Inbred BN; Rats, Inbred WF; Respiratory Hypersensitivity; Serotonin; Tachykinins

1987
Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:12

    Topics: Animals; Blood Proteins; Brain; Capsaicin; Dura Mater; Electric Stimulation; Guinea Pigs; Headache; Inflammation; Iodine Radioisotopes; Nerve Fibers, Myelinated; Rats; Rats, Inbred Strains

1987
Effect of capsaicin on croton oil and TPA induced tumorigenesis and inflammation.
    Proceedings of the Western Pharmacology Society, 1986, Volume: 29

    Topics: Animals; Capsaicin; Croton Oil; Female; Inflammation; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate

1986
The effect of nerve lesions on the inflammatory response to injury.
    Journal of neuroscience research, 1985, Volume: 13, Issue:3

    Topics: Animals; Blister; Capsaicin; Cell Count; Hydroxydopamines; Inflammation; Leukocytes; Oxidopamine; Peripheral Nerves; Proteins; Rats; Rats, Inbred Strains; Sympathectomy, Chemical

1985
Neurogenic flare responses following topical application of capsaicin in humans.
    Annals of neurology, 1985, Volume: 18, Issue:4

    Topics: Administration, Topical; Afferent Pathways; Aging; Capsaicin; Humans; Inflammation; Nervous System Physiological Phenomena; Nociceptors; Osmolar Concentration; Pain; Statistics as Topic

1985