capsaicin and Hypothermia

capsaicin has been researched along with Hypothermia in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.12)18.7374
1990's4 (12.12)18.2507
2000's12 (36.36)29.6817
2010's12 (36.36)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Bogenstaetter, M; Breitenbucher, JG; Carruthers, NI; Chang, L; Chaplan, SR; Codd, EE; Dax, SL; Dubin, AE; Gonzales, L; Hoey, K; Jetter, M; Lee, DH; Liu, C; Lord, B; Mazur, C; Nasser, N; Rizzolio, M; Shah, C; Swanson, DM; Zhang, SP1
Gerzanich, V; Jia, X; Keledjian, K; Kim, KT; Sarkar, A; Sherani, NA; Simard, JM; Tsymbalyuk, O; Wilhelmy, BE1
An, H; Ding, Y; Duan, Y; Elmadhoun, O; He, X; Ji, X; Liu, X; Meng, R; Shi, J; Wu, D; Zhang, J1
Balasubramanian, A; Cao, Z; Marrelli, SP; Pautler, RG; Pedersen, SE; Romero, J1
Corrigan, JJ; Garami, A; Gavva, NR; Gomtsyan, A; Kym, PR; Lehto, SG; McDonald, HA; Pakai, E; Pinter, E; Reilly, RM; Romanovsky, AA; Zhu, DXD1
Ann, J; Bahrenberg, G; Blumberg, PM; Choi, S; Christoph, T; Frank-Foltyn, R; Kim, C; Kim, E; Lee, J; Lee, S; Stockhausen, H1
An, H; Ding, Y; Dong, K; Duan, Y; He, X; Ji, X; Meng, R; Shi, J; Wei, W; Wu, C; Wu, D; Zhang, J; Zhang, M; Zhang, Y; Zhi, X1
Furube, E; Inagaki, H; Kurganov, E; Miyata, S; Park, Y1
Balasubramanian, A; Cao, Z; Marrelli, SP1
Dow, J; Hale, SL; Kay, G; Kloner, RA; Simkhovich, BZ1
Ann, J; Bahrenberg, G; Blumberg, PM; Choi, S; Christoph, T; Cui, M; Frank-Foltyn, R; Hong, S; Jung, A; Kang, DW; Kim, HM; Kim, MY; Kim, S; Lee, J; Ryu, H; Stockhausen, H1
Osaka, T1
Bradbury, M; Gogas, K; Jaffe, R; McMackin, M; Mills, C; Slee, D; Yu, J; Zininberg, E1
Almeida, MC; Balaskó, M; Dogan, MD; Eales, J; Gavva, NR; Molchanova, AY; Oliveira, DL; Patel, S; Pétervári, E; Romanovsky, AA; Steiner, AA; Székely, M; Wanner, SP1
Comelli, F; Costa, B; D'Agostino, B; de Novellis, V; De Petrocellis, L; Di Marzo, V; Gatta, L; Guida, F; Luongo, L; Maione, S; Matteis, M; Sullo, N1
Caterina, MJ; Horiuchi, N; Iida, T; Shimizu, I1
Elekes, K; Helyes, Z; McDougall, JJ; Németh, J; Pintér, E; Szabó, A; Szolcsányi, J; Varga, A; Zhang, C1
Almeida, FR; Campos, AR; Cavalcante, IJ; Chaves, MH; Costa, CL; Lima, AF; Lima, RC; Oliveira, FA; Rao, VS; Santos, FA; Silva, RM1
Cowan, A; Ding, Z; Rawls, SM3
Cowan, A; Ding, Z; Rawls, SM; Tallarida, R1
Bannon, AW; Deng, H; Gavva, NR; Gore, A; Han, B; Hovland, DN; Juan, T; Klionsky, L; Kuang, R; Le, A; Lehto, SG; Louis, JC; Magal, E; Norman, MH; Surapaneni, S; Tamir, R; Treanor, JJ; Wang, J; Youngblood, B; Zhu, D1
Bilbao, A; Ciccocioppo, R; Cippitelli, A; Gorriti, MA; Massi, M; Navarro, M; Piomelli, D; Rodríguez de Fonseca, F1
Ahmed, MM; Dosoky, RM; Hirayama, H; Iwami, M; Mahmoud, ME; Nikami, H; Shiina, T; Shimizu, Y; Takewaki, T1
Brendel, K; Buck, SH; Burks, TF; Miller, MS1
Jancsó-Gabor, A1
Andrews, PL; Gupta, AN; Stock, MJ; Wong, TT; Woods, AJ1
Dirig, DM; Hua, XY; Yaksh, TL1
Day, R; Glickman-Weiss, EL; Hearon, CM; Nelson, AG1
Angelogianni, P; Shimada, SG; Stitt, JT1
Blumberg, PM; Joo, F; Szallasi, A1
Blumberg, PM; Szallasi, A1

Trials

1 trial(s) available for capsaicin and Hypothermia

ArticleYear
Does capsaicin affect physiologic and thermal responses of males during immersion in 22 degrees C?
    Aviation, space, and environmental medicine, 1998, Volume: 69, Issue:11

    Topics: Adult; Animals; Body Temperature Regulation; Capsaicin; Cold Temperature; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Hypothermia; Immersion; Male; Men; Oxygen Consumption; Rats; Time Factors

1998

Other Studies

32 other study(ies) available for capsaicin and Hypothermia

ArticleYear
Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Administration, Oral; Aminopyridines; Analgesics; Animals; Biological Availability; Body Temperature; Calcium; Capsaicin; Cell Line; Humans; Hypothermia; Ion Channels; Male; Pain Measurement; Piperazines; Rats; Structure-Activity Relationship; TRPV Cation Channels

2005
A Direct Comparison of Physical Versus Dihydrocapsaicin-Induced Hypothermia in a Rat Model of Traumatic Spinal Cord Injury.
    Therapeutic hypothermia and temperature management, 2022, Volume: 12, Issue:2

    Topics: Animals; Capsaicin; Hypothermia; Hypothermia, Induced; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2022
Dihydrocapsaicin (DHC) enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat.
    Brain research, 2017, Sep-15, Volume: 1671

    Topics: Animals; Apoptosis; Body Temperature; Brain Injuries; Brain Ischemia; Capsaicin; Hypothermia; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Infusions, Intra-Arterial; Ischemic Attack, Transient; Male; Neuroprotection; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Stroke

2017
TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke.
    Scientific reports, 2017, 12-15, Volume: 7, Issue:1

    Topics: Animals; Brain Ischemia; Capsaicin; Diffusion Tensor Imaging; Disease Models, Animal; Hypothermia; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Recovery of Function; Stroke; TRPV Cation Channels

2017
TRPV1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: Compounds' pharmacological profiles, in vivo targets, thermoeffectors recruited and implications for drug development.
    Acta physiologica (Oxford, England), 2018, Volume: 223, Issue:3

    Topics: Analgesics; Animals; Capsaicin; Drug Development; Hypothermia; Male; Mice; Protons; Rats, Sprague-Dawley; Rats, Wistar; Thermogenesis; TRPV Cation Channels; Vasodilation

2018
4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands.
    Bioorganic & medicinal chemistry, 2018, 08-15, Volume: 26, Issue:15

    Topics: Acetamides; Amides; Binding Sites; Capsaicin; Humans; Hydrogen-Ion Concentration; Hypothermia; Ligands; Molecular Docking Simulation; Protein Structure, Tertiary; Structure-Activity Relationship; TRPV Cation Channels

2018
Inflammatory cytokines are involved in dihydrocapsaicin (DHC) and regional cooling infusion (RCI)-induced neuroprotection in ischemic rat.
    Brain research, 2019, 05-01, Volume: 1710

    Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Ischemia; Capsaicin; Cytokines; Hypothermia; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Infusions, Intra-Arterial; Ischemic Attack, Transient; Male; Neuroprotection; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke

2019
Oral gavage of capsaicin causes TRPV1-dependent acute hypothermia and TRPV1-independent long-lasting increase of locomotor activity in the mouse.
    Physiology & behavior, 2019, 07-01, Volume: 206

    Topics: Animals; Body Temperature; Body Temperature Regulation; Capsaicin; Hypothalamus; Hypothermia; Mice; Mice, Knockout; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; TRPV Cation Channels

2019
Pharmacologically induced hypothermia via TRPV1 channel agonism provides neuroprotection following ischemic stroke when initiated 90 min after reperfusion.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Jan-15, Volume: 306, Issue:2

    Topics: Animals; Blood Pressure; Brain Ischemia; Capsaicin; Cerebrum; Heart Rate; Hypothermia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reperfusion Injury; Sensory System Agents; Stroke; TRPV Cation Channels

2014
Capsaicin-induced cardioprotection. Is hypothermia or the salvage kinase pathway involved?
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:4

    Topics: Administration, Topical; Animals; Capsaicin; Cardiotonic Agents; Female; Heart Rate; Hypothermia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Myocardium; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction

2014
Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists.
    Bioorganic & medicinal chemistry, 2015, Nov-01, Volume: 23, Issue:21

    Topics: Amides; Analgesics; Animals; Binding Sites; Capsaicin; Humans; Hypothermia; Mice; Molecular Conformation; Molecular Docking Simulation; Structure-Activity Relationship; TRPV Cation Channels

2015
Hypothermia induced by inhibition of fatty acid metabolism in anesthetized rats: contributions of the forebrain and vagal afferents.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:6

    Topics: Anesthesia; Animals; Capsaicin; Fatty Acids; Hypothermia; Injections, Intravenous; Male; Prosencephalon; Rats; Rats, Wistar; Thioglycolates; Vagus Nerve

2017
Effects of the transient receptor potential vanilloid 1 antagonist A-425619 on body temperature and thermoregulation in the rat.
    Neuroscience, 2008, Sep-22, Volume: 156, Issue:1

    Topics: Administration, Oral; Animals; Body Temperature; Body Temperature Regulation; Capsaicin; Circadian Rhythm; Drug Administration Schedule; Fever; Hypothalamus; Hypothermia; Isoquinolines; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Time Factors; TRPV Cation Channels; Urea

2008
The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors.
    The Journal of physiology, 2011, May-01, Volume: 589, Issue:Pt 9

    Topics: Analysis of Variance; Animals; Arachidonic Acids; Body Temperature Regulation; Brain; Camphanes; Capsaicin; Disease Models, Animal; Diterpenes; Endocannabinoids; Female; Hypothermia; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Lipopolysaccharides; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Sulfonamides; Time Factors; TRPV Cation Channels

2011
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature.
    Pharmacological research, 2012, Volume: 66, Issue:3

    Topics: Analgesics; Animals; Body Temperature; Bronchoconstriction; Capsaicin; Edema; Female; Hyperalgesia; Hypothermia; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Respiratory System; Sciatic Nerve; TRPV Cation Channels

2012
5-Iodoresiniferatoxin evokes hypothermia in mice and is a partial transient receptor potential vanilloid 1 agonist in vitro.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Animals; Body Temperature; Calcium; Capsaicin; Diterpenes; Humans; Hypothermia; Ion Channels; Mice; Mice, Inbred C57BL; TRPV Cation Channels

2005
Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat.
    Neuroscience letters, 2005, Sep-09, Volume: 385, Issue:2

    Topics: Analgesics; Anilides; Animals; Capsaicin; Cells, Cultured; Cinnamates; Dose-Response Relationship, Drug; Drug Interactions; Hypothermia; Ion Channels; Male; Mice; Mice, Inbred BALB C; Neurons, Afferent; Nociceptors; Pain; Peripheral Nervous System; Rats; Rats, Wistar; Sensory Receptor Cells; Substance P; Trigeminal Ganglion; TRPV Cation Channels

2005
Attenuation of capsaicin-induced acute and visceral nociceptive pain by alpha- and beta-amyrin, a triterpene mixture isolated from Protium heptaphyllum resin in mice.
    Life sciences, 2005, Oct-21, Volume: 77, Issue:23

    Topics: Administration, Oral; Analgesics; Animals; Behavior, Animal; Burseraceae; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Hypothermia; Mice; Motor Activity; Oleanolic Acid; Pain; Postural Balance; Resins, Plant; Sleep

2005
Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors.
    Brain research, 2005, Dec-14, Volume: 1065, Issue:1-2

    Topics: Anilides; Animals; Benzoxazines; Body Temperature; Calcium Channel Blockers; Camphanes; Capsaicin; Cinnamates; Hypothermia; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; TRPV Cation Channels

2005
Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:4

    Topics: Amidohydrolases; Anilides; Animals; Arachidonic Acids; Body Temperature; Capsaicin; Cinnamates; Endocannabinoids; Hypothermia; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; TRPV Cation Channels

2006
Capsaicin and nitric oxide synthase inhibitor interact to evoke a hypothermic synergy.
    Neuroscience letters, 2006, Nov-27, Volume: 409, Issue:1

    Topics: Animals; Benzoxazines; Body Temperature; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Hypothermia; Injections, Intraventricular; Male; Morpholines; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; TRPV Cation Channels

2006
The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Mar-28, Volume: 27, Issue:13

    Topics: Acrylamides; Animals; Benzothiazoles; Blood-Brain Barrier; Body Temperature Regulation; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cells, Cultured; CHO Cells; Conserved Sequence; Cricetinae; Cricetulus; Dogs; Female; Fever; Humans; Hypothermia; Macaca fascicularis; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Species Specificity; Sulfonamides; Thiourea; TRPV Cation Channels

2007
The anandamide transport inhibitor AM404 reduces ethanol self-administration.
    The European journal of neuroscience, 2007, Volume: 26, Issue:2

    Topics: Alcohol Drinking; Animals; Arachidonic Acids; Capsaicin; Central Nervous System Depressants; Conditioning, Operant; Depression, Chemical; Endocannabinoids; Ethanol; Extinction, Psychological; Hypothermia; Male; Motor Activity; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reinforcement, Psychology; Saccharin; Self Administration; TRPV Cation Channels

2007
5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Animals; Body Temperature; Brain; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fluoxetine; Hypothermia; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin; Serotonin Antagonists; Synaptic Transmission

2008
Capsaicin pretreatment attenuates LPS-induced hypothermia through TRPV1-independent mechanisms in chicken.
    Life sciences, 2008, Jun-06, Volume: 82, Issue:23-24

    Topics: Animals; Animals, Newborn; Body Temperature; Capsaicin; Chickens; Hypothermia; Lipopolysaccharides; Liver; Lung; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; TRPV Cation Channels

2008
Dihydrocapsaicin-induced hypothermia and substance P depletion.
    European journal of pharmacology, 1982, Sep-24, Volume: 83, Issue:3-4

    Topics: Animals; Body Temperature Regulation; Capsaicin; Fatty Acids, Unsaturated; Female; Ganglia, Spinal; Hypothermia; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P

1982
Anaesthesia-like condition and/or potentiation of hexobarbital sleep produced by pungent agents in normal and capsaicin-desensitized rats.
    Acta physiologica Academiae Scientiarum Hungaricae, 1980, Volume: 55, Issue:1

    Topics: Anesthesia; Animals; Body Temperature; Body Temperature Regulation; Butanones; Capsaicin; Desensitization, Immunologic; Drug Synergism; Fatty Acids, Unsaturated; Female; Guaiacol; Hexobarbital; Hypothermia; Ketones; Male; Preoptic Area; Rats; Sleep

1980
Thermoregulatory effects of resiniferatoxin in the rat.
    European journal of pharmacology, 1994, Oct-24, Volume: 264, Issue:2

    Topics: Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Capsaicin; Diterpenes; Hot Temperature; Hypothermia; Injections, Subcutaneous; Male; Neurotoxins; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Drug

1994
Temperature dependency of basal and evoked release of amino acids and calcitonin gene-related peptide from rat dorsal spinal cord.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jun-01, Volume: 17, Issue:11

    Topics: Animals; Aspartic Acid; Body Temperature; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Chromatography, High Pressure Liquid; Cross Reactions; Fever; Glutamic Acid; Glycine; Hypothermia; Male; Organ Culture Techniques; Potassium; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Synaptic Transmission

1997
Effects of cold and capsaicin desensitization on prostaglandin E hypothermia in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:6

    Topics: Animals; Body Temperature Regulation; Capsaicin; Cold Temperature; Hypothermia; Injections, Intraperitoneal; Male; Prostaglandins E; Rats; Rats, Inbred Strains

1990
Duration of desensitization and ultrastructural changes in dorsal root ganglia in rats treated with resiniferatoxin, an ultrapotent capsaicin analog.
    Brain research, 1989, Nov-27, Volume: 503, Issue:1

    Topics: Animals; Body Temperature Regulation; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Drug Tolerance; Ganglia, Spinal; Hypothermia; Mitochondria; Neurons, Afferent; Rats

1989
Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper.
    Neuroscience, 1989, Volume: 30, Issue:2

    Topics: Animals; Capsaicin; Diterpenes; Female; Hypothermia; Inflammation; Pain; Rats; Rats, Inbred Strains

1989