capsaicin and Facial Pain

capsaicin has been researched along with Facial Pain in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (7.89)	18.2507
2000's	23 (30.26)	29.6817
2010's	38 (50.00)	24.3611
2020's	9 (11.84)	2.80

Authors

Authors	Studies
Goto, S; Haji, A; Kodama, D; Miyazawa, K; Ohi, Y; Tamada, M	1
Bereiter, DA; Iwata, K; Katagiri, A; Kato, T; Kishimoto, S; Niwa, H; Oyamaguchi, A; Sato, H; Toyoda, H	1
Almeida, RN; Braga, RM; Castro, RD; Costa, TKVLD; Dantas, NV; Limeira, RRT; Salvadori, MGDSS; Scotti, L; Sousa, FB; Tomaz-Morais, JF	1
Abbasnejad, M; Esmaeili-Mahani, S; Kooshki, R; Lobbezoo, F; Raoof, M; Tajabadi, A	1
Abbasnejad, M; Dehghani, A; Esmaeili-Mahani, S; Lobbezoo, F; Raoof, M; Soleimani, AH	1
Aguiar, DA; Chichorro, JG; Dos Reis, RC; Kopruszinski, CM; Nones, CFM	1
Binda, NS; Borges, MH; Carobin, NV; Castro Junior, CJ; Ferreira, J; Gomez, MV; Kushmerick, C; Pinto Nagem, RA; Ribeiro, FM; Rita Pereira, EM; Santos, DC; Silva Júnior, CA; Silva, JF; Souza, JM	1
Antunes, FTT; Caminski, ES; Dallegrave, E; de Freitas, LM; de Souza, AH; Gomez, MV; Junior, CADS; Pereira, EMR	1
Čeko, M; Kim, HJ; Kim, SG; Lee, JJ; Lee, SA; Park, BY; Park, H; Roy, M; Wager, TD; Woo, CW	1
Bereiter, DA; Gionhaku, N; Iinuma, T; Iwata, K; Katagiri, A; Kubo, A; Lee, J; Mikuzuki, L; Ohara, K; Okada, S; Saito, H; Suzuki, T	1
Acevedo-Quiroz, M; de la Rosa-Lugo, V; Déciga-Campos, M; Rios, MY	1
Araya, EI; Chichorro, JG; Cunha, JMD; Ferreira, LEN; Kopruszinski, CM; Nones, CFM	1
Abbas Farshid, A; Delkhosh-Kasmaie, F; Erfanparast, A; Tamaddonfard, E	1
Allen, KD; Caudle, RM; Neubert, JK; Rohrs, EL	1
Barbosa, TM; Barroso, LKV; Batista, FLA; Campos, AR; da Silva, ARA; Damasceno, MBMV; de Melo, JMA; de Oliveira, BA; Guedes, MIF; Holanda, DKR; Lima, MDCL; Magalhães, FEA; Moura, LFWG; Nogueira, AB; Santos, SAAR; Serpa, OF	1
Abbasnejad, M; Esmaeili-Mahani, S; Kooshki, R; Raoof, M	2
Alves, YA; Campos, AR; Coelho, RF; Magalhaes, FEA; Santos, SAAR; Soares, ICR; Tavares, KCS; Vieira-Neto, AE	1
Bereiter, DA; Iinuma, T; Iwata, K; Katagiri, A; Lee, J; Ohara, K; Okada, S; Saito, H	1
Boucher, Y; Carstens, E; Carstens, MI; Merrill, AW; Sawyer, CM; Zanotto, KL	1
Gu, JG; Ling, JX; Xu, GY; Zuo, X	1
Heir, GM; Khan, J; Nasri-Heir, C	1
Alves, PB; Araújo, AA; Bonjardim, LR; de Lucca Júnior, W; Lucchese, AM; Menezes, PP; Quintans, JS; Quintans-Júnior, LJ; Santos, MR; Siqueira-Lima, PS	1
Boucher, Y; Carstens, E; Carstens, MI; Simons, CT	1
Chichorro, JG; Cruz, LS; Kopruszinski, CM	1
Anderson, EM; Caudle, RM; Jenkins, AC; Neubert, JK	1
Bereiter, DA; Khasabov, SG; Malecha, P; Noack, J; Okamoto, K; Simone, DA; Tabakov, J	1
Chichorro, JG; Hummig, W; Kopruszinski, CM	1
Furukawa, A; Honda, K; Iwata, K; Kita, K; Noma, N; Shinoda, M	1
Ando, T; Baad-Hansen, L; Naganawa, T; Svensson, P	1
Allen, KD; Caudle, RM; Jacobs, BY; Kloefkorn, HE; Lakes, EH; Neubert, JK; Rohrs, EL	1
Aktumsek, A; Amarante, RKL; Amarante, RS; Barreto, AS; Barreto, RSS; Coutinho, HDM; Duarte, MC; Menezes, IRA; Nascimento, TS; Pereira, EWM; Quintans, JSS; Quintans-Júnior, LJ; Zengin, G	1
Abbasnejad, M; Bahaaddini, M; Esmaeili-Mahani, S; Khatamsaz, S; Raoof, M	1
Almeida, JRGS; Araújo, AAS; Castro, FF; Coutinho, HDM; Gopalsamy, RG; Martins, AOBPB; Menezes, IRA; Oliveira, MRC; Oliveira, RCM; Quintans, JSS; Quintans-Júnior, LJ; Serafini, MR; Shanmugam, S; Silva, BAF; Silva, JC; Thangaraj, P	1
Braga, RM; de Almeida, RN; de Castro, RD; de Sousa, DP; de Sousa, FB; deM Pordeus, LC; Tomaz-Morais, JF	1
Hu, JW; Lam, DK; Sessle, BJ	1
Arendt-Nielsen, L; Arima, T; Minagi, S; Svensson, P	1
Lee, JS; Ro, JY; Zhang, Y	1
Arendt-Nielsen, L; Boudreau, SA; Sessle, BJ; Svensson, P; Wang, K	1
Ahn, DK; Jung, SJ; Kim, HJ; Kim, JS; Kim, SA; Kim, YH; Lee, MK; Oh, SB; Yeon, KY	1
Arendt-Nielsen, L; Cairns, BE; Sessle, BJ; Svensson, P; Wang, K	2
Honda, K; Inoue, K; Iwata, K; Kondo, E; Okumura, M; Shibuta, K; Shinoda, M; Yasuda, K; Yasuda, M	1
Almeida, JR; Araujo, AA; Araújo, DA; Bonjardim, LR; De Sousa, DP; Gelain, DP; Gonçalves, JC; Melo, MS; Onofre, AC; Quintans-Júnior, LJ	1
Macfarlane, TV; Morrison, R; Mujakperuo, HR; Watson, M	1
Bokrand-Donatelli, Y; Caudle, RM; Hester, J; Neubert, JK; Nolan, TA	1
Hitomi, S; Iwata, K; Shinoda, M; Suzuki, I	1
Brodsky, M; Cho, JH; Cho, YJ; Fang, JY; Kim, EJ; Kim, KW; Song, MY	1
Murray, GM; Peck, CC; Whittle, T; Zhao, NN	1
Araujo, BS; Botelho, MA; Damascena, NP; Dias, AS; Estevam, CS; Lima, AC; Melo, MS; Oliveira, MG; Paixão, MS; Quintans, LJ; Santana, MT	1
Araújo, BS; Damascena, NP; de Lima, AC; de Santana, MT; Dias, AS; dos S Estevam, C; Fernandes, XA; Lima, CA; Melo, M; Paixão, MS; Porto, YC; Quintans Júnior, LJ; Santos, CC	1
Baad-Hansen, L; List, T; Lu, S; Svensson, P; Zhang, Z	1
Alvarez, P; Hernández, A; Paeile, C; Pelissier, T; Saavedra, G	1
Arendt-Nielsen, L; Graven-Nielsen, T; Sohn, MK; Svensson, P	1
Baad-Hansen, L; Jensen, TS; Svensson, P	1
Cairns, BE; Hu, JW; Lam, DK; Sessle, BJ	1
Capra, NF; Ro, JY	1
Childeric, A; Dallel, R; Gaydier, AM; Luccarini, P; Voisin, D	1
Chung, SC; Kho, HS; Kim, YK; Lee, YS	1
Andersen, OK; Arendt-Nielsen, L; Gazerani, P	1
Chaves, MH; Cunha, GM; Guedes, MA; Holanda Pinto, SA; Pinto, LM; Rao, VS; Santos, FA	1
da Rosa, RS; Faot, F; Pastre, T; Westphalen, FH	1
Balasubramaniam, R; Hersh, EV; Pinto, A	1
Hersh, EV; Ochs, HA; Pertes, RA	1
Canavan, D; Graff-Radford, SB; Gratt, BM	1
Epstein, JB; Marcoe, JH	1
Arendt-Nielsen, L; Bak, P; Bjerring, P; Hjorth, T; Svensson, P; Troest, T	1
Chisholm, K; Cousins, MJ; Vickers, ER; Walker, S	1
Hirano, M; Lincoff, NS; Rath, PP	1
Clark, GT; Merrill, RL; Padilla, M	1
Arendt-Nielsen, L; Cruccu, G; Romaniello, A; Svensson, P	1
Arendt-Nielsen, L; Cruccu, G; McMillan, AS; Romaniello, A; Svensson, P	1
Eli, I; Gavish, A; Gazit, E; Halachmi, M; Winocur, E	1
Arendt-Nielsen, L; Arima, T; Svensson, P	2
Dallel, R; Pajot, J; Pelissier, T	1

Reviews

6 review(s) available for capsaicin and Facial Pain

Article	Year
Topical medications as treatment of neuropathic orofacial pain. Dental clinics of North America, 2013, Volume: 57, Issue:3 Topics: Administration, Cutaneous; Capsaicin; Cyclooxygenase Inhibitors; Diclofenac; Facial Pain; Humans; Lidocaine; Neuralgia; Sensory System Agents; Voltage-Gated Sodium Channel Blockers	2013
Pharmacological interventions for pain in patients with temporomandibular disorders. The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Benzodiazepines; Capsaicin; Facial Pain; Glucosamine; Humans; Neuromuscular Agents; Propranolol; Randomized Controlled Trials as Topic; Temporomandibular Joint Disorders	2010
Treatment of painful post-traumatic peripheral neuropathy with capsaicin in an edentulous patient with extreme resorption in the mental region: a case report. The journal of contemporary dental practice, 2008, Mar-01, Volume: 9, Issue:3 Topics: Alveolar Bone Loss; Capsaicin; Cranial Nerve Diseases; Denture, Complete, Lower; Facial Pain; Female; Humans; Middle Aged; Sensory System Agents; Trigeminal Nerve Injuries	2008
Pharmacologic management of temporomandibular disorders. Oral and maxillofacial surgery clinics of North America, 2008, Volume: 20, Issue:2 Topics: Adrenal Cortex Hormones; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Capsaicin; Facial Pain; Humans; Hypnotics and Sedatives; Narcotics; Neuromuscular Agents; Sensory System Agents; Temporomandibular Joint Disorders	2008
Topical capsaicin-pharmacology and potential role in the treatment of temporomandibular pain. The Journal of clinical dentistry, 1994, Volume: 5, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Disease; Facial Pain; Humans; Nerve Fibers; Substance P; Temporomandibular Joint Disorders	1994
Topical medications for orofacial neuropathic pain: a review. Journal of the American Dental Association (1939), 2000, Volume: 131, Issue:2 Topics: Administration, Topical; Analgesics; Anesthetics, Local; Capsaicin; Cranial Nerve Diseases; Cranial Nerve Neoplasms; Drug Carriers; Drug Delivery Systems; Facial Pain; Humans; Neuralgia; Neuroma; Phosphatidylcholines	2000

Trials

13 trial(s) available for capsaicin and Facial Pain

Article	Year
Orofacial antinociceptive activity of (S)-(-)-perillyl alcohol in mice: a randomized, controlled and triple-blind study. International journal of oral and maxillofacial surgery, 2017, Volume: 46, Issue:5 Topics: Animals; Capsaicin; Facial Pain; Formaldehyde; Glutamic Acid; Male; Mice; Monoterpenes; Morphine; Pain Measurement	2017
Vascular and psychophysical effects of topical capsaicin application to orofacial tissues. Journal of orofacial pain, 2009,Summer, Volume: 23, Issue:3 Topics: Adult; Body Temperature; Capsaicin; Cross-Over Studies; Facial Pain; Female; Humans; Laser-Doppler Flowmetry; Lip; Male; Pain Measurement; Regional Blood Flow; Sensory System Agents; Sensory Thresholds; Tongue	2009
Efficacy of a 0.1% capsaicin hydrogel patch for myofascial neck pain: a double-blinded randomized trial. Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:7 Topics: Administration, Topical; Adolescent; Adult; Aged; Bandages, Hydrocolloid; Capsaicin; Double-Blind Method; Facial Pain; Female; Humans; Male; Middle Aged; Neck Pain; Pain Measurement; Sensory System Agents; Transdermal Patch; Treatment Outcome; Young Adult	2012
Somatosensory profiling of intra-oral capsaicin and menthol in healthy subjects. European journal of oral sciences, 2013, Volume: 121, Issue:1 Topics: Administration, Topical; Adult; Analysis of Variance; Capsaicin; Cross-Over Studies; Double-Blind Method; Facial Pain; Female; Gingiva; Humans; Male; Menthol; Models, Biological; Pain Measurement; Pain Threshold; Statistics, Nonparametric	2013
Effects of experimental muscle pain on mechanical properties of single motor units in human masseter. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2004, Volume: 115, Issue:1 Topics: Adult; Capsaicin; Electric Stimulation; Electromyography; Electrophysiology; Facial Pain; Female; Humans; Isometric Contraction; Male; Masseter Muscle; Motor Neurons; Muscle Cells; Pain Measurement	2004
A human model of intraoral pain and heat hyperalgesia. Journal of orofacial pain, 2003,Fall, Volume: 17, Issue:4 Topics: Administration, Topical; Adult; Analysis of Variance; Capsaicin; Cross-Over Studies; Double-Blind Method; Facial Pain; Female; Hot Temperature; Humans; Hyperalgesia; Male; Models, Biological; Mouth Mucosa; Pain Measurement; Sensory Thresholds; Statistics, Nonparametric; Surveys and Questionnaires	2003
Influence of topical capsaicin on facial sensitivity in response to experimental pain. Journal of oral rehabilitation, 2007, Volume: 34, Issue:1 Topics: Administration, Topical; Adult; Analgesics, Non-Narcotic; Capsaicin; Epidermis; Facial Pain; Female; Hot Temperature; Humans; Male; Physical Stimulation; Sensation; Sensory Thresholds	2007
Interactions between glutamate and capsaicin in inducing muscle pain and sensitization in humans. European journal of pain (London, England), 2008, Volume: 12, Issue:5 Topics: Adult; Capsaicin; Double-Blind Method; Drug Interactions; Facial Pain; Female; Glutamic Acid; Humans; Injections, Intramuscular; Male; Masseter Muscle; Neurotoxins; Pain Measurement; Pain Threshold; Pressure	2008
Topical application of capsaicin for treatment of oral neuropathic pain and trigeminal neuralgia. Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:2 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Burning Mouth Syndrome; Capsaicin; Facial Pain; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Toothache; Treatment Outcome; Trigeminal Neuralgia	1994
Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:1 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Capsaicin; Chi-Square Distribution; Chronic Disease; Facial Pain; Female; Humans; Infusions, Intravenous; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain Measurement; Phentolamine; Prilocaine; Reflex Sympathetic Dystrophy; Sex Factors; Single-Blind Method; Surveys and Questionnaires; Sympatholytics; Temporomandibular Joint Disorders; Toothache	1998
Modulation of exteroceptive suppression periods in human jaw-closing muscles induced by summation of nociceptive and non-nociceptive inputs. Experimental brain research, 2000, Volume: 132, Issue:3 Topics: Adult; Capsaicin; Electromyography; Facial Pain; Female; Humans; Jaw; Male; Masseter Muscle; Nerve Fibers; Nerve Fibers, Myelinated; Neural Inhibition; Neurons, Afferent; Nociceptors; Presynaptic Terminals; Reaction Time; Reflex; Touch	2000
Topical application of capsaicin for the treatment of localized pain in the temporomandibular joint area. Journal of orofacial pain, 2000,Winter, Volume: 14, Issue:1 Topics: Activities of Daily Living; Administration, Topical; Adult; Analgesics; Analysis of Variance; Arthralgia; Capsaicin; Chi-Square Distribution; Double-Blind Method; Facial Pain; Female; Follow-Up Studies; Humans; Male; Mandible; Masticatory Muscles; Ointments; Pain Measurement; Palpation; Pharmaceutical Vehicles; Placebo Effect; Placebos; Temporomandibular Joint; Temporomandibular Joint Disorders	2000
Capsaicin-induced muscle hyperalgesia in the exercised and non-exercised human masseter muscle. Journal of orofacial pain, 2000,Summer, Volume: 14, Issue:3 Topics: Adult; Analysis of Variance; Bite Force; Bruxism; Capsaicin; Electromyography; Exercise; Facial Pain; Humans; Male; Masseter Muscle; Muscle Contraction; Pain Measurement; Pain Threshold; Statistics, Nonparametric	2000

Other Studies

57 other study(ies) available for capsaicin and Facial Pain

Article	Year
Modulation of excitatory synaptic transmissions by TRPV1 in the spinal trigeminal subnucleus caudalis neurons of neuropathic pain rats. European journal of pharmacology, 2021, Dec-15, Volume: 913 Topics: Animals; Capsaicin; Chronic Pain; Disease Models, Animal; Excitatory Postsynaptic Potentials; Facial Pain; Humans; Male; Neuralgia; Neurons; Rats; Synaptic Transmission; Trigeminal Caudal Nucleus; TRPV Cation Channels	2021
Enhanced Ocular Surface and Intraoral Nociception via a Transient Receptor Potential Vanilloid 1 Mechanism in a Rat Model of Obstructive Sleep Apnea. Neuroscience, 2022, 02-10, Volume: 483 Topics: Animals; Capsaicin; Facial Pain; Nociception; Rats; Rats, Sprague-Dawley; Sleep Apnea, Obstructive	2022
Orofacial antinociceptive effects of perillyl alcohol associated with codeine and its possible modes of action. Brazilian oral research, 2022, Volume: 36 Topics: Analgesics; Animals; Capsaicin; Codeine; Facial Pain; Glutamic Acid; Mice; Molecular Docking Simulation; Monoterpenes; Receptors, Glutamate	2022
Repeated gentle handling or maternal deprivation during the neonatal stage increases adult male rats' baseline orofacial pain responsiveness. Archives of oral biology, 2023, Volume: 151 Topics: Animals; Capsaicin; Facial Pain; Formaldehyde; Male; Maternal Deprivation; Nitroglycerin; Nociception; Rats	2023
Apelin signalling in the periaqueductal grey matter alleviates capsaicin-evoked pulpal nocifensive behaviour and capsaicin-induced spatial learning and memory impairments in rat. International endodontic journal, 2023, Volume: 56, Issue:8 Topics: Animals; Apelin; Capsaicin; Facial Pain; Male; Memory Disorders; Naloxone; Periaqueductal Gray; Rats; Rats, Wistar; Spatial Learning	2023
The opposing contribution of neurotrophin-3 and nerve growth factor to orofacial heat hyperalgesia in rats. Behavioural pharmacology, 2020, Volume: 31, Issue:1 Topics: Animals; Capsaicin; Facial Pain; Hot Temperature; Hyperalgesia; Male; Nerve Growth Factor; Neurotrophin 3; Rats; Rats, Wistar; Receptor, trkA; Trigeminal Neuralgia	2020
Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model. Neuropharmacology, 2020, 01-01, Volume: 162 Topics: Acrolein; Anilides; Animals; Calcium; Calcium Signaling; Capsaicin; Cinnamates; Disease Models, Animal; Facial Pain; Glutamic Acid; HEK293 Cells; Humans; Inhibitory Concentration 50; Male; Neuropeptides; Nociception; Patch-Clamp Techniques; Rats; Sensory System Agents; Transfection; Trigeminal Ganglion; TRPA1 Cation Channel; TRPV Cation Channels	2020
Analgesic effects of the CTK 01512-2 toxin in different models of orofacial pain in rats. Pharmacological reports : PR, 2020, Volume: 72, Issue:3 Topics: Analgesics; Animals; Calcium Channels, N-Type; Capsaicin; Disease Models, Animal; Facial Pain; Freund's Adjuvant; Glutamic Acid; Hyperalgesia; Male; Neuralgia; omega-Conotoxins; Pain Measurement; Rats; Rats, Wistar; TRPA1 Cation Channel	2020
A neuroimaging biomarker for sustained experimental and clinical pain. Nature medicine, 2021, Volume: 27, Issue:1 Topics: Adolescent; Adult; Aversive Agents; Biomarkers; Capsaicin; Connectome; Facial Pain; Female; Functional Neuroimaging; Humans; Low Back Pain; Magnetic Resonance Imaging; Male; Models, Neurological; Nerve Net; Pain; Pain Measurement; Predictive Value of Tests; Sensitivity and Specificity; Taste; Young Adult	2021
Ascending projections of nociceptive neurons from trigeminal subnucleus caudalis: A population approach. Experimental neurology, 2017, Volume: 293 Topics: Animals; Capsaicin; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Facial Pain; Male; Mediodorsal Thalamic Nucleus; Neural Pathways; Nociceptors; Parabrachial Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sensory System Agents; Statistics, Nonparametric; Stilbamidines; Trigeminal Nuclei; Ventral Thalamic Nuclei	2017
Antinociceptive effect of natural and synthetic alkamides involves TRPV1 receptors. The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:7 Topics: Amides; Analgesics; Animals; Asteraceae; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Facial Pain; Female; Mice; Pain Measurement; TRPV Cation Channels	2017
Role of peripheral and central TRPV1 receptors in facial heat hyperalgesia in streptozotocin-induced diabetic rats. Brain research, 2017, Sep-01, Volume: 1670 Topics: Animals; Capsaicin; Diabetes Mellitus, Experimental; Diterpenes; Face; Facial Pain; Hot Temperature; Hyperalgesia; Male; Pain Threshold; Rats; Rats, Wistar; Trigeminal Ganglion; TRPV Cation Channels	2017
Role of ventrolateral orbital cortex muscarinic and nicotinic receptors in modulation of capsaicin-induced orofacial pain-related behaviors in rats. European journal of pharmacology, 2017, Nov-15, Volume: 815 Topics: Animals; Behavior, Animal; Capsaicin; Facial Pain; Male; Muscarinic Antagonists; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic	2017
Behavioral characteristics of capsaicin mediated cutaneous, myogenic, and arthrogenic orofacial nociception in rats. Archives of oral biology, 2018, Volume: 92 Topics: Animals; Behavior, Animal; Capsaicin; Facial Pain; Female; Masseter Muscle; Nociception; Nociceptors; Pain Measurement; Physical Stimulation; Rats; Sensory System Agents; Temporomandibular Joint	2018
Orofacial antinociceptive effect of Mimosa tenuiflora (Willd.) Poiret. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97 Topics: Acrolein; Analgesics; Animals; Antioxidants; Capsaicin; Chemical Fractionation; Chlorocebus aethiops; Ethanol; Facial Pain; Glutamic Acid; Glyburide; Mice; Mimosa; Motor Activity; Naloxone; NG-Nitroarginine Methyl Ester; Nociception; Phenols; Plant Extracts; Rats, Wistar; Temporomandibular Joint; Vero Cells	2018
The effect of CA1 administration of orexin-A on hippocampal expression of COX-2 and BDNF in a rat model of orofacial pain. Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:9 Topics: Animals; Benzoxazoles; Brain-Derived Neurotrophic Factor; Capsaicin; Cyclooxygenase 2; Disease Models, Animal; Facial Pain; Hippocampus; Male; Naphthyridines; Neurons; Orexin Receptors; Orexins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Urea	2018
Oleanolic acid promotes orofacial antinociception in adult zebrafish (Danio rerio) through TRPV1 receptors. Chemico-biological interactions, 2019, Feb-01, Volume: 299 Topics: Acetanilides; Analgesics; Animals; Behavior, Animal; Binding Sites; Capsaicin; Facial Pain; Formaldehyde; Molecular Docking Simulation; Oleanolic Acid; Protein Structure, Tertiary; Purines; Ruthenium Red; Thermodynamics; TRPV Cation Channels; Zebrafish; Zebrafish Proteins	2019
Differential activation of ascending noxious pathways associated with trigeminal nerve injury. Pain, 2019, Volume: 160, Issue:6 Topics: Animals; Capsaicin; Extracellular Signal-Regulated MAP Kinases; Facial Pain; Hyperalgesia; Male; Nociceptors; Parabrachial Nucleus; Rats, Sprague-Dawley; Spinal Cord; Trigeminal Nerve Injuries	2019
Capsaicin avoidance as a measure of chemical hyperalgesia in orofacial nerve injury models. Neuroscience letters, 2013, May-24, Volume: 543 Topics: Animals; Avoidance Learning; Capsaicin; Constriction, Pathologic; Facial Pain; Hot Temperature; Hyperalgesia; Ligation; Lingual Nerve Injuries; Male; Neurons; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Touch; Trigeminal Nerve Injuries; Trigeminal Nuclei	2013
Operant behavioral responses to orofacial cold stimuli in rats with chronic constrictive trigeminal nerve injury: effects of menthol and capsazepine. Molecular pain, 2013, Jun-14, Volume: 9 Topics: Animals; Behavior, Animal; Capsaicin; Cold Temperature; Conditioning, Operant; Facial Nerve; Facial Pain; Hyperalgesia; Male; Menthol; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trigeminal Nerve; Trigeminal Nerve Injuries; TRPM Cation Channels	2013
β-cyclodextrin complex containing Lippia grata leaf essential oil reduces orofacial nociception in mice - evidence of possible involvement of descending inhibitory pain modulation pathway. Basic & clinical pharmacology & toxicology, 2014, Volume: 114, Issue:2 Topics: Animals; beta-Cyclodextrins; Capsaicin; Facial Pain; Formaldehyde; Glutamic Acid; Lippia; Male; Mice; Morphine; Nociception; Oils, Volatile; Pain Measurement; Periaqueductal Gray; Plant Leaves	2014
Effects of gustatory nerve transection and/or ovariectomy on oral capsaicin avoidance in rats. Pain, 2014, Volume: 155, Issue:4 Topics: Analysis of Variance; Animals; Body Weight; Capsaicin; Choice Behavior; Chorda Tympani Nerve; Dose-Response Relationship, Drug; Drinking Behavior; Facial Pain; Female; Male; Oncogene Proteins v-fos; Ovariectomy; Rats; Sensory System Agents; Time Factors	2014
Intraganglionar resiniferatoxin prevents orofacial inflammatory and neuropathic hyperalgesia. Behavioural pharmacology, 2014, Volume: 25, Issue:2 Topics: Animals; Capsaicin; Carrageenan; Cold Temperature; Disease Models, Animal; Diterpenes; Facial Pain; Formaldehyde; Hot Temperature; Hyperalgesia; Male; Neuralgia; Neurons; Nociception; Rats; Rats, Wistar; Sensory System Agents; Trigeminal Ganglion; TRPV Cation Channels	2014
The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device. PloS one, 2014, Volume: 9, Issue:2 Topics: Analysis of Variance; Animals; Capsaicin; Conditioning, Operant; Facial Pain; Male; Menthol; Nociception; Pain Measurement; Rats; Rats, Sprague-Dawley; Temperature; TRPM Cation Channels; TRPV Cation Channels	2014
Activation of rostral ventromedial medulla neurons by noxious stimulation of cutaneous and deep craniofacial tissues. Journal of neurophysiology, 2015, Jan-01, Volume: 113, Issue:1 Topics: Action Potentials; Adenosine Triphosphate; Animals; Capsaicin; Eye; Facial Pain; Forelimb; Hindlimb; Male; Medulla Oblongata; Microelectrodes; Neurons; Nociceptive Pain; Physical Stimulation; Rats, Sprague-Dawley; Skin; Temporomandibular Joint	2015
Pregabalin reduces acute inflammatory and persistent pain associated with nerve injury and cancer in rat models of orofacial pain. Journal of oral & facial pain and headache, 2014,Fall, Volume: 28, Issue:4 Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Chronic Pain; Disease Models, Animal; Facial Neoplasms; Facial Pain; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Irritants; Lip Diseases; Male; Neoplasm Transplantation; Orbit; Pain Measurement; Pregabalin; Random Allocation; Rats, Wistar; Sensory System Agents; Trigeminal Neuralgia	2014
TRPA1 contributes to capsaicin-induced facial cold hyperalgesia in rats. European journal of oral sciences, 2014, Volume: 122, Issue:6 Topics: Acetanilides; Anilides; Animals; Behavior, Animal; Capsaicin; Cinnamates; Cold Temperature; Electromyography; Face; Facial Pain; Hot Temperature; Hyperalgesia; Injections, Intradermal; Male; Neural Conduction; Neurons; Physical Stimulation; Purines; Rats; Rats, Sprague-Dawley; Reflex; Sensory System Agents; Synaptic Transmission; Trigeminal Ganglion; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels	2014
Influence of topical application of capsaicin, menthol and local anesthetics on intraoral somatosensory sensitivity in healthy subjects: temporal and spatial aspects. Experimental brain research, 2015, Volume: 233, Issue:4 Topics: Administration, Topical; Adult; Analysis of Variance; Anesthetics, Local; Antipruritics; Capsaicin; Dose-Response Relationship, Drug; Facial Pain; Female; Healthy Volunteers; Humans; Hyperalgesia; Male; Menthol; Pain Threshold; Sensory System Agents; Time Factors; Visual Analog Scale; Young Adult	2015
A novel operant-based behavioral assay of mechanical allodynia in the orofacial region of rats. Journal of neuroscience methods, 2015, Jun-15, Volume: 248 Topics: Analgesics, Opioid; Animals; Capsaicin; Conditioning, Operant; Equipment Design; Facial Pain; Female; Hyperalgesia; Morphine; Pain Measurement; Pressure; Rats, Sprague-Dawley; Touch	2015
The role of trigeminal nucleus caudalis orexin 1 receptors in orofacial pain transmission and in orofacial pain-induced learning and memory impairment in rats. Physiology & behavior, 2016, Apr-01, Volume: 157 Topics: Animals; Benzoxazoles; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Learning Disabilities; Male; Maze Learning; Memory Disorders; Motor Activity; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Sensory System Agents; Spatial Learning; Trigeminal Nuclei; Urea	2016
Evidence for the involvement of TNF-α and IL-1β in the antinociceptive and anti-inflammatory activity of Stachys lavandulifolia Vahl. (Lamiaceae) essential oil and (-)-α-bisabolol, its main compound, in mice. Journal of ethnopharmacology, 2016, Sep-15, Volume: 191 Topics: Analgesics; Animals; Anti-Infective Agents; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Flame Ionization; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Interleukin-1beta; Male; Mice; Monocyclic Sesquiterpenes; Nociception; Nociceptive Pain; Oils, Volatile; Phytotherapy; Plant Extracts; Plant Oils; Plants, Medicinal; Pleurisy; Sesquiterpenes; Stachys; Time Factors; Tumor Necrosis Factor-alpha	2016
The role of trigeminal nucleus caudalis orexin 1 receptor in orofacial pain-induced anxiety in rat. Neuroreport, 2016, Oct-19, Volume: 27, Issue:15 Topics: Animals; Anxiety; Benzoxazoles; Capsaicin; Disease Models, Animal; Exploratory Behavior; Facial Pain; Formaldehyde; Male; Maze Learning; Microinjections; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pain Measurement; Rats; Rats, Wistar; Time Factors; Trigeminal Nuclei; Urea	2016
Enhancement of orofacial antinociceptive effect of carvacrol, a monoterpene present in oregano and thyme oils, by β-cyclodextrin inclusion complex in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84 Topics: Animals; beta-Cyclodextrins; Capsaicin; Cymenes; Diazepam; Facial Pain; Hand Strength; Male; Mice; Monoterpenes; Morphine; Nociception; Origanum; Pain Measurement; Thymus Plant	2016
Glutamate and capsaicin effects on trigeminal nociception I: Activation and peripheral sensitization of deep craniofacial nociceptive afferents. Brain research, 2009, Jan-28, Volume: 1251 Topics: Afferent Pathways; Animals; Capsaicin; Face; Facial Pain; Glutamic Acid; Male; Mechanoreceptors; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sensory Receptor Cells; Sensory System Agents; Trigeminal Nerve; TRPV Cation Channels	2009
Effect of capsaicin-evoked jaw-muscle pain on intramuscular blood-flow. Archives of oral biology, 2009, Volume: 54, Issue:3 Topics: Adult; Analysis of Variance; Bite Force; Capsaicin; Facial Pain; Humans; Injections, Intramuscular; Isometric Contraction; Male; Masseter Muscle; Pain Threshold; Regional Blood Flow; Young Adult	2009
Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain, 2009, Volume: 144, Issue:3 Topics: Acrylamides; Afferent Pathways; Animals; Ankyrins; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channels; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Hyperalgesia; Injections, Intramuscular; Male; Masticatory Muscles; Mustard Plant; Nociceptors; Pain Measurement; Pain Threshold; Plant Oils; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Trigeminal Ganglion; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels	2009
Curcumin produces an antihyperalgesic effect via antagonism of TRPV1. Journal of dental research, 2010, Volume: 89, Issue:2 Topics: Animals; Capsaicin; Cell Line; Curcumin; Facial Pain; Hot Temperature; Humans; Hyperalgesia; Injections, Intraperitoneal; Injections, Subcutaneous; Kidney; Male; Nociceptors; Nose; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion; TRPV Cation Channels	2010
Interactions of glutamate and capsaicin-evoked muscle pain on jaw motor functions of men. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2010, Volume: 121, Issue:6 Topics: Adult; Analysis of Variance; Capsaicin; Double-Blind Method; Electromyography; Facial Pain; Glutamic Acid; Humans; Jaw; Male; Movement; Muscle Contraction; Muscle, Skeletal; Pain Measurement	2010
Alternation of gene expression in trigeminal ganglion neurons following complete Freund's adjuvant or capsaicin injection into the rat face. Journal of molecular neuroscience : MN, 2010, Volume: 42, Issue:2 Topics: Adjuvants, Immunologic; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Face; Facial Pain; Freund's Adjuvant; Gene Expression Regulation; Male; Nerve Fibers, Unmyelinated; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; RNA, Untranslated; Sensory Receptor Cells; Sensory System Agents; Trigeminal Ganglion; Vibrissae	2010
Antinociceptive effects of citronellal in formalin-, capsaicin-, and glutamate-induced orofacial nociception in rodents and its action on nerve excitability. Journal of orofacial pain, 2010,Summer, Volume: 24, Issue:3 Topics: Action Potentials; Acyclic Monoterpenes; Aldehydes; Analgesics; Animals; Capsaicin; Facial Pain; Formaldehyde; Glutamates; Male; Mice; Monoterpenes; Morphine; Motor Activity; Narcotics; Neural Conduction; Nociceptors; Pain; Rats; Rats, Wistar; Sciatic Nerve; Sensory System Agents	2010
Adaptation of a novel operant orofacial testing system to characterize both mechanical and thermal pain. Behavioural brain research, 2011, Mar-01, Volume: 217, Issue:2 Topics: Adaptation, Physiological; Analysis of Variance; Animals; Capsaicin; Conditioning, Operant; Disease Models, Animal; Facial Pain; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley	2011
Involvement of transient receptor potential vanilloid 1 in ectopic pain following inferior alveolar nerve transection in rats. Neuroscience letters, 2012, Mar-28, Volume: 513, Issue:1 Topics: Anilides; Animals; Antigens, Nuclear; Behavior, Animal; Capsaicin; Cell Count; Cinnamates; Electric Stimulation; Extracellular Signal-Regulated MAP Kinases; Facial Pain; Grooming; Immunohistochemistry; Male; Mandibular Nerve; Nerve Tissue Proteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion; TRPV Cation Channels; Vibrissae	2012
The effects of capsaicin-induced intraoral mucosal pain on jaw movements in humans. Journal of orofacial pain, 2012,Fall, Volume: 26, Issue:4 Topics: Accelerometry; Adaptation, Physiological; Adult; Anxiety; Capsaicin; Case-Control Studies; Depression; Facial Pain; Female; Humans; Image Processing, Computer-Assisted; Male; Mandible; Mastication; Models, Neurological; Motor Activity; Mouth Mucosa; Movement; Psychological Tests; Sensory System Agents; Surveys and Questionnaires	2012
Hyptis pectinata: redox protection and orofacial antinociception. Phytotherapy research : PTR, 2013, Volume: 27, Issue:9 Topics: Analgesics; Animals; Biphenyl Compounds; Capsaicin; Facial Pain; Free Radical Scavengers; Glutamic Acid; Hyptis; Lipid Peroxidation; Male; Mice; Morphine; Pain Measurement; Picrates; Plant Extracts; Plant Leaves; Thiobarbituric Acid Reactive Substances	2013
Orofacial antinociceptive effect and antioxidant properties of the hydroethanol extract of Hyptis fruticosa salmz ex Benth. Journal of ethnopharmacology, 2013, Mar-07, Volume: 146, Issue:1 Topics: Analgesics; Animals; Antioxidants; Behavior, Animal; Capsaicin; Ethanol; Facial Pain; Formaldehyde; Glutamic Acid; Hyptis; Male; Mice; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Solvents; Terpenes; Thiobarbituric Acid Reactive Substances	2013
Synergistic antinociceptive effects of ketamine and morphine in the orofacial capsaicin test in the rat. Anesthesiology, 2003, Volume: 99, Issue:4 Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Facial Pain; Ketamine; Male; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley	2003
Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats. Brain research, 2005, Jun-07, Volume: 1046, Issue:1-2 Topics: Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Facial Pain; Inflammation; Jaw; Male; Muscle, Skeletal; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Valine	2005
Assessing mechanical sensitivity of masseter muscle in lightly anesthetized rats: a model for craniofacial muscle hyperalgesia. Neuroscience research, 2006, Volume: 56, Issue:1 Topics: Analgesics, Non-Narcotic; Anesthesia; Animals; Behavior; Bradykinin; Capsaicin; Facial Pain; Glutamic Acid; Humans; Hyperalgesia; Male; Masseter Muscle; Models, Biological; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley	2006
The orofacial formalin test in the mouse: a behavioral model for studying physiology and modulation of trigeminal nociception. The journal of pain, 2006, Volume: 7, Issue:12 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Facial Pain; Formaldehyde; Lip; Male; Mice; Morphine; Narcotics; Nociceptors; Pain Measurement; Psychomotor Performance; Trigeminal Nerve	2006
Site-specific, dose-dependent, and sex-related responses to the experimental pain model induced by intradermal injection of capsaicin to the foreheads and forearms of healthy humans. Journal of orofacial pain, 2007,Fall, Volume: 21, Issue:4 Topics: Adult; Capsaicin; Dose-Response Relationship, Drug; Epidemiologic Methods; Facial Pain; Female; Forearm; Forehead; Humans; Injections, Intradermal; Male; Models, Theoretical; Pain; Sensory System Agents; Sex Factors; Time Factors; Trigeminal Nerve	2007
Antinoceptive effect of triterpenoid alpha,beta-amyrin in rats on orofacial pain induced by formalin and capsaicin. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:8 Topics: Analgesics; Animals; Burseraceae; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Facial Pain; Formaldehyde; Male; Molecular Structure; Oleanolic Acid; Phytotherapy; Rats; Rats, Wistar	2008
Traumatic dysesthesia of the trigeminal nerve. Journal of orofacial pain, 1994,Fall, Volume: 8, Issue:4 Topics: Administration, Topical; Aged; Antidepressive Agents, Tricyclic; Capsaicin; Desipramine; Drug Therapy, Combination; Facial Pain; Female; Humans; Irritants; Male; Mandible; Mandibular Fractures; Nortriptyline; Paresthesia; Postoperative Complications; Rhytidoplasty; Trigeminal Nerve Injuries; Trigeminal Neuralgia	1994
Human mastication modulated by experimental trigeminal and extra-trigeminal painful stimuli. Journal of oral rehabilitation, 1996, Volume: 23, Issue:12 Topics: Adult; Capsaicin; Chewing Gum; Cold Temperature; Electromyography; Facial Pain; Female; Frontal Bone; Hand; Humans; Male; Mandible; Mastication; Masticatory Muscles; Motor Neurons; Movement; Nociceptors; Pain Measurement; Palate; Physical Stimulation; Pressure; Temporomandibular Joint; Trigeminal Nerve	1996
The treatment of periocular and facial pain with topical capsaicin. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 1998, Volume: 18, Issue:1 Topics: Administration, Topical; Aged; Capsaicin; Eye Diseases; Facial Pain; Female; Humans; Male; Middle Aged; Ointments; Pain; Trigeminal Neuralgia	1998
Effect of experimental pain from trigeminal muscle and skin on motor cortex excitability in humans. Brain research, 2000, Nov-03, Volume: 882, Issue:1-2 Topics: Adult; Analysis of Variance; Capsaicin; Electromagnetic Phenomena; Electromyography; Evoked Potentials, Motor; Facial Muscles; Facial Pain; Female; Humans; Male; Motor Cortex; Muscle Tonus; Saline Solution, Hypertonic; Skin; Trigeminal Nerve	2000
Effect of jaw muscle pain and soreness evoked by capsaicin before sleep on orofacial motor activity during sleep. Journal of orofacial pain, 2001,Summer, Volume: 15, Issue:3 Topics: Adult; Area Under Curve; Bite Force; Capsaicin; Electroencephalography; Electromyography; Facial Pain; Female; Humans; Injections, Intramuscular; Male; Masseter Muscle; Multivariate Analysis; Muscle Cramp; Pain Measurement; Pain Threshold; Polysomnography; Sleep Bruxism; Statistics as Topic	2001
The orofacial capsaicin test in rats: effects of different capsaicin concentrations and morphine. Pain, 2002, Volume: 96, Issue:1-2 Topics: Analgesics, Opioid; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Grooming; Injections, Subcutaneous; Male; Morphine; Nociceptors; Rats; Rats, Sprague-Dawley; Vibrissae	2002