capsaicin has been researched along with Edema in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (12.14) | 18.7374 |
| 1990's | 51 (36.43) | 18.2507 |
| 2000's | 46 (32.86) | 29.6817 |
| 2010's | 24 (17.14) | 24.3611 |
| 2020's | 2 (1.43) | 2.80 |
| Authors | Studies |
|---|---|
| Annunziata, R; Appendino, G; Cravotto, G; Palmisano, G; Szallasi, A | 1 |
| Lei, F; Yan, Z | 1 |
| Belboukhari, N; Cheriti, A; Ould El Hadj-Khelil, A; Seddiki, LS; Sekkoum, K; Sulaiman, MR | 1 |
| Coutinho, HDM; da Costa, RHS; da Silva, BAF; de Menezes, IRA; Fernandes, CN; Garcia, TR; Leite, LHI; Ribeiro-Filho, J; Wanderley, AG | 1 |
| Borbély, É; Botz, B; Helyes, Z; Kiss, T; Pintér, E; Szabadfi, K; Szolcsányi, J | 1 |
| Aghajani, M; Amani, A; Esmaeli, F; Faramarzi, MA; Ghazi-Khansari, M; Ghiasi, Z | 1 |
| Chen, HS; Li, FP; Li, XQ; Lin, Q; Liu, BJ; Qu, F; Wang, Y; Wen, WW | 1 |
| Agis, ER; Demirel-Yilmaz, E; Ercan, N; Uludag, MO | 1 |
| Dolan, S; Goldie, M | 1 |
| Almeida, FR; Amaral, MP; Chaves, MH; Costa, DA; Figueiredo, KA; Júnior, FB; Oliveira, FA; Oliveira, IS; Oliveira, RC; Silva, FV | 1 |
| Alexandre-Moreira, MS; Alves, Hda S; Campesatto, EA; Cavalcante-Silva, LH; Chaves, MC; de Queiroz, AC; Dias, Tde L; Melo, GM; Santos, Mda S | 1 |
| Alves, MS; Chibli, LA; Del-Vechio-Vieira, G; Fabri, RL; Gasparetto, CM; Pinto, NC; Rodrigues, KC; Scio, E; Sousa, OV | 1 |
| Cayasso, M; László, JF; Pórszász, R; Szalai, A; Újhelyi, J; Újhelyi, Z; Vecsernyés, M | 1 |
| Bölcskei, K; Borbély, É; Botz, B; Csepregi, JZ; Helyes, Z; Kenyér, T; Kereskai, L; Kiss, T; Mócsai, A; Pintér, E; Szolcsányi, J | 1 |
| Camargo, LL; Costa, SK; Denadai-Souza, A; Fernandes, E; Grant, A; Lima, C; Mesquita, FP; Muscará, MN; Schenka, A; Soares, AG; Yshii, LM | 1 |
| Borbély, É; Helyes, Z; Kemény, Á; Markovics, A; McDougall, JJ; Pintér, E; Quinn, JP; Sándor, K; Szolcsányi, J | 1 |
| Bai, ZT; Cheng, M; Ji, YH; Jiang, F; Liu, T; Pang, XY | 1 |
| Bach-Rojecky, L; Dominis, M; Lacković, Z | 1 |
| Imai, Y; Iwasaki, Y; Kurohane, K; Maruyama, T; Shiba, T; Watanabe, T | 1 |
| Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Vale, ML | 1 |
| Casale, R; Ceccherelli, F; Gagliardi, G; Ori, C; Roveri, A | 1 |
| Alexandre-Moreira, MS; Barbosa-Filho, JM; Chaves, MC; da Silva, DJ; de Aquino, AB; de Araújo-Júnior, JX; de Athayde-Filho, PF; de Lira, DP; de Miranda, GE; de Queiroz, AC; de Souza, ET; Lorenzo, VP; Mella, EA; Santos, BV | 1 |
| Boller, S; Cabrini, DA; Marques, MC; Otuki, MF; Pizzolatti, MG; Santos, EP; Soldi, C; Zampronio, AR | 1 |
| Fu, Z; Ge, L; Hu, X; Huang, W; Lin, H; Lin, R; Qian, H; Zhang, H; Zhou, J | 1 |
| Appenzeller, M; Bigliardi, P; Buclin, T; Grouzmann, E; Pannatier, A | 1 |
| André, E; Cabrini, DA; da Silveira Prudente, A; Dalmolin, GD; Ferreira, J; Guerra, GP; Oliveira, SM; Otuki, MF; Rossato, MF; Silva, CR | 1 |
| de Oliveira, SM; Ferreira, J; Gomez, MV; Hoffmeister, C; Rossato, MF; Trevisan, G | 1 |
| Alexandre-Moreira, MS; Chung, M; Costa, FF; dos Santos, JL; Franco-Penteado, CF; Gambero, S; Kutlar, A; Lanaro, C; Lima, LM; Meiler, SE; Wade, M; Yerigenahally, S | 1 |
| Dolan, S; Graham, A; Iannitti, T | 1 |
| Comelli, F; Costa, B; D'Agostino, B; de Novellis, V; De Petrocellis, L; Di Marzo, V; Gatta, L; Guida, F; Luongo, L; Maione, S; Matteis, M; Sullo, N | 1 |
| Athayde, ML; Boligon, AA; Ferreira, J; Guerra, GP; Klafke, JZ; Oliveira, SM; Rosa, F; Rossato, MF; Tonello, R; Trevisan, G; Walker, CI; Zanon, RB | 1 |
| Fereidoni, M; Niazmand, S; Sepehri, Z | 1 |
| Li, C; Liu, L; Pai, R; Pasricha, PJ; Shenoy, M; Zhu, Y | 1 |
| Ashton, D; Fransen, JF; Hens, KA; Heylen, L; Hillen, LC; Janssens, F; Jurzak, MR; Leysen, JE; Mahieu, M; Megens, AA; Vermeire, JC; Vermote, PC | 1 |
| Ceccherelli, F; Gagliardi, G; Giron, G; Ruzzante, L | 1 |
| Guo, JJ; Huang, HT; Wang, DS | 1 |
| Beirith, A; Calixto, JB; Santos, AR | 1 |
| Cury, Y; Zanchet, EM | 1 |
| Gábor, M | 1 |
| Abdel-Salam, OM; Arbid, MS; Baiuomy, AR; El-batran, S | 1 |
| Bánvölgyi, A; Brain, SD; Ghosh, M; Helyes, ZS; Melegh, B; Pintér, E; Pozsgai, G; Szolcsányi, J | 1 |
| Haas, DA; Hu, JW; Tang, ML | 1 |
| Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S | 1 |
| Dougherty, PM; Weng, HR | 1 |
| El Kouhen, R; Faltynek, CR; Gauvin, DM; Gomtsyan, A; Honore, P; Jarvis, MF; Lee, CH; Marsh, K; Mikusa, J; Sullivan, JP; Wismer, CT; Zhong, C; Zhu, CZ | 1 |
| Nies, M; Ro, JY; Zhang, Y | 1 |
| Abdel-Salam, OM | 1 |
| Cavalcante, IJ; Lima, MA; Maia, JL; Melo, CM; Rao, VS; Santos, FA; Silveira, ER; Vieira, GA | 1 |
| Calixto, JB; Claudino, RF; Ferreira, J; Kassuya, CA | 1 |
| Beaulieu, P; De Léan, A; Guindon, J; LoVerme, J; Piomelli, D | 1 |
| Alves, D; Jesse, CR; Nogueira, CW; Pinto, LG; Rocha, JB; Savegnago, L; Zeni, G | 1 |
| Arendt-Nielsen, L; Chen, HS; He, X; Wang, Y; Wen, WW; You, HJ | 1 |
| Amadesi, S; Bunnett, NW; Chapman, K; Cottrell, GS; Gedda, K; Hollenberg, MD; Knecht, W; Mohlin, J; Peterson, A; Skåregärde, A; Vergnolle, N | 1 |
| Bagoly, T; Börzsei, R; Elekes, K; Helyes, Z; Márk, L; Németh, J; Pintér, E; Pozsgai, G; Reglodi, D; Szolcsányi, J; Tóth, G | 1 |
| Fang, L; Li, D; Lin, Q; Xu, X; Zou, X | 1 |
| Jesse, CR; Nogueira, CW; Pinto, LG; Savegnago, L | 1 |
| Ghelfi, E; Gonzalez-Flecha, B; Lawrence, J; Rhoden, CR; Wellenius, GA | 1 |
| Abu-Asab, M; Iadarola, MJ; Jenkins, AC; Karai, LJ; Mannes, AJ; Neubert, JK; Zawatski, L | 1 |
| Brito, GA; Chaves, MH; Cunha, GM; Lima-Júnior, RC; Rao, VS; Santos, FA; Sousa, DI | 1 |
| Brain, SD; Helyes, Z; Perkecz, A; Pintér, E; Pozsgai, G; Sándor, K; Szolcsányi, J | 1 |
| Alves, MK; Carvalho, TA; Cunha, FQ; de Oliveira, JR; Leite, CE; Lunardelli, A; Poloni, JA; Spiller, F; Vieira, SM | 1 |
| Chahl, LA; Manley, SW | 1 |
| Fitzgerald, M | 1 |
| Folkers, K; Lundberg, JM; Martling, CR; Rosell, S; Saria, A | 1 |
| Saria, A | 1 |
| Anggård, A; Lundberg, JM; Lundblad, L; Saria, A | 1 |
| Donnerer, J; Gamillscheg, A; Holzer, P; Lembeck, F | 1 |
| Lundberg, JM; Saria, A | 1 |
| Lundberg, JM; Martling, CR; Saria, A | 1 |
| Chahl, LA; Morton, CR | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 5 |
| McDonald, DM; Sulakvelidze, I | 1 |
| Erion, MD; Gilligan, JP; Jeng, AY; Lovato, SJ | 1 |
| Blazsó, G; Gábor, M | 2 |
| Brain, SD; Newbold, P | 1 |
| Amann, R; Donnerer, J; Lanz, I; Schuligoi, R | 1 |
| Holzer, P; Lippe, IT; Stabentheiner, A | 1 |
| Bertrand, C; Desai, MC; Geppetti, P; Nadel, JA; Piedimonte, G; Snider, RM | 1 |
| Fujii, T; Hagiwara, D; Maeda, Y; Matsuo, M; Miyake, H; Murai, M; Yamaoka, M | 1 |
| Griesbacher, T; Legat, FJ; Lembeck, F | 1 |
| Buckley, TL; Nijkamp, FP | 1 |
| Brain, SD; Escott, KJ | 1 |
| Gibson, SJ; Helme, RD; Morris, GC | 1 |
| Amann, R; Donnerer, J; Herzeg, G; Schuligoi, R | 1 |
| Inoue, H; Koshihara, Y; Nagata, N; Shibata, S | 1 |
| Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH | 1 |
| do Patrocínio, M; Lapa e Silva, JR; Leick-Maldonado, EA; Martins, MA; Paiva, SO; Sakae, RS; Saldiva, PH; Tibério, IF; Turco, GM; Warth, TN | 1 |
| Asaka, T; Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Desouza, IA; Ribeiro-DaSilva, G | 1 |
| Antunes, E; Brain, SD; Costa, SK; de Nucci, G | 1 |
| Hargreaves, KM; Kilo, S; Richardson, JD | 1 |
| Kamata, R; Kobayashi, H; Saito, S; Sato, I; Sugawara, E; Suzuki, T; Tachikawa, E; Tomizawa, N; Wada, S | 1 |
| Althuber, P; Griengl, S; Griesbacher, T; Lembeck, F; Rainer, I; Zenz, M | 1 |
| Ceccherelli, F; Gagliardi, G; Giron, G; Visentin, R | 1 |
| Helyes, Z; Németh, J; Oroszi, G; Pintér, E; Szolcsányi, J | 1 |
| Bileviciute, I; Lundeberg, T; Stenfors, C; Theodorsson, E | 1 |
| Blazsó, G; Gábor, M; Rázga, Z | 1 |
| Ceccherelli, F; Faggian, L; Gagliardi, G; Giron, G; Loprete, F | 1 |
| Damas, J; Liégeois, JF | 1 |
| Brain, SD; Cao, T; Gerard, NP | 1 |
| Alves, RV; Calixto, JB; Chakravarty, S; de Campos, RO; Ferreira, J; Kyle, DJ; Mavunkel, BJ | 1 |
| Alexandre-Moreira, MS; Araújo, CC; Piuvezam, MR; Thomas, G | 1 |
| D'Orléans-Juste, P; Piovezan, AP; Rae, GA; Souza, GE | 1 |
| Calixto, JB; Campos, MM; Ferreira, PK | 1 |
| Liu, XJ; Reid, A; Sawynok, J | 1 |
| Antunes, E; Costa, SK; da Silva, GR; Linardi, A | 1 |
| Cirillo, R; Evangelista, S; Lippi, A; Maggi, CA; Manzini, S; Vieira, C | 1 |
| Antunes, E; Brain, SD; Camargo, E; Costa, SK; De Nucci, G; Esquisatto, LC; Gambero, A | 1 |
| Davison, CA; McKnight, W; Miller, MJ; Musah, RA; Sandoval, M; Thompson, JH; Trentacosti, AM; Vergnolle, N; Wallace, JL | 1 |
| Brain, SD; Cao, T; Gerard, NP; Grant, AD | 1 |
| Brain, SD; Gerard, NP; Rawlingson, A | 1 |
| Agashe, GS; Clark, JD; Davies, MF; Guo, TZ; Kingery, WS; Maze, M | 1 |
| Eltorp, CT; Hansen, AJ; Ingvardsen, BK; Jørgensen, TK; Lundbaek, JA; Olsen, UB; Thomsen, C | 1 |
| Robinson, MD; Shannon, S | 1 |
| Arvier, PT; Chahl, LA; Ladd, RJ | 1 |
| Kiernan, JA | 1 |
| Gábor, M; Rázga, Z | 1 |
| Cappugi, P; Lotti, T; Tsampau, D | 1 |
| Fujii, T; Kiyotoh, S; Maeda, Y; Morimoto, H; Murai, M; Nishikawa, M | 1 |
| Garry, MG; Hargreaves, KM | 1 |
| Brain, SD; Buckley, TL; Jose, PJ; Williams, TJ | 1 |
| Cowan, A; Wheeler-Aceto, H | 1 |
| Brain, SD; Buckley, TL; Williams, TJ | 1 |
| Mantione, CR; Rodriguez, R | 1 |
| Ohkubo, T; Shibata, M; Takahashi, H | 1 |
| Brodda-Jansen, G; Hedqvist, P; Lundeberg, T; Raud, J; Theodorsson, E | 1 |
| Brain, SD; Hughes, SR | 1 |
| Cseh, G; Gábor, M; Rázga, Z | 1 |
| Bohne, RL; Brand, LM; Fanelli, R; Lade, DA; Loomans, ME; Maddin, CS; Moorehead, DP; Reller, HH; Schwen, RJ; Skare, KL | 1 |
| Inoki, R; Shibutani, T; Yonehara, N | 1 |
| Fujii, T; Morimoto, H; Senoh, H | 1 |
| Imai, Y; Inoki, R; Shibutani, T; Yonehara, N | 1 |
| Lundberg, JM; Martling, CR | 1 |
| Dalsgaard, CJ; Haegerstrand, A; Jonsson, CE | 1 |
| Leyden, JJ; Soschin, D | 1 |
4 review(s) available for capsaicin and Edema
| Article | Year |
|---|---|
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Capsaicin and sensory neurones--a review.
Topics: Animals; Axonal Transport; Axons; Capsaicin; Cholecystokinin; Edema; Fatty Acids, Unsaturated; Ganglia, Spinal; Nerve Degeneration; Nerve Fibers; Neurons, Afferent; Pain; Rats; Reflex; Sensation; Substance P | 1983 |
Rehabilitation of peripheral nerve injuries.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Capsaicin; Denervation; Discrimination, Psychological; Edema; Electric Stimulation Therapy; Exercise Therapy; Humans; Hyperesthesia; Mexiletine; Muscle, Skeletal; Peripheral Nerve Injuries; Wallerian Degeneration; Wounds and Injuries | 2002 |
[Capsaicin-induced mouse ear edema and its management].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Dose-Response Relationship, Drug; Edema; Histamine Antagonists; Male; Mice; Time Factors | 1991 |
3 trial(s) available for capsaicin and Edema
| Article | Year |
|---|---|
Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Edema; Furans; Ginkgolides; Hindlimb; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Sensory System Agents; Vocalization, Animal | 2013 |
Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers.
Topics: Capsaicin; Carbonated Beverages; Cross-Over Studies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Edema; Erythema; Humans; Injections, Intradermal; Male; Pain; Pyrazines; Sitagliptin Phosphate; Skin; Substance P; Triazoles; Vasodilation | 2011 |
Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Edema; Female; Humans; Hyperemia; Mesenteric Arteries; Neurogenic Inflammation; Phytotherapy; Plant Extracts; Rats; Rats, Inbred F344; Receptor, PAR-2; Receptors, Thrombin; Stomach; Vasodilation | 2001 |
133 other study(ies) available for capsaicin and Edema
| Article | Year |
|---|---|
Synthesis and evaluation of phorboid 20-homovanillates: discovery of a class of ligands binding to the vanilloid (capsaicin) receptor with different degrees of cooperativity.
Topics: Animals; Body Temperature; Diterpenes; Edema; Homovanillic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Proteins; Molecular Structure; Phorbol Esters; Protein Binding; Rats; Receptors, Drug; Spinal Cord | 1996 |
Antinociceptive and Anti-inflammatory Effect of Corynoline in Different Nociceptive and Inflammatory Experimental Models.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Berberine Alkaloids; Capsaicin; Carrageenan; Cytokines; Edema; Formaldehyde; Glutamates; Inflammation; Inflammation Mediators; Mice; Models, Theoretical; Nociception; Pain; Plant Extracts; Water | 2022 |
Pharmacological studies on aqueous extract of Launaea arborescens from southwest Algeria.
Topics: Algeria; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Behavior, Animal; Capsaicin; Edema; Formaldehyde; Histamine; Hot Temperature; Inflammation; Male; Medicine, Traditional; Mice, Inbred BALB C; Pain; Pain Measurement; Plant Extracts; Serotonin; Solutions; TRPV Cation Channels | 2021 |
HPLC profile and antiedematogenic activity of Ximenia americana L. (Olacaceae) in mice models of skin inflammation.
Topics: Animals; Arachidonic Acid; Capsaicin; Chromatography, High Pressure Liquid; Croton Oil; Dermatitis; Dose-Response Relationship, Drug; Edema; Female; Histamine; Histamine Antagonists; Mice; Olacaceae; Phenol; Plant Extracts | 2018 |
Complex Role of Capsaicin-Sensitive Afferents in the Collagen Antibody-Induced Autoimmune Arthritis of the Mouse.
Topics: Animals; Ankle Joint; Antibodies; Arthritis, Experimental; Body Weight; Capsaicin; Disease Models, Animal; Diterpenes; Edema; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Severity of Illness Index; X-Ray Microtomography | 2018 |
Enhancing analgesic and anti-inflammatory effects of capsaicin when loaded into olive oil nanoemulsion: An in vivo study.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chemistry, Pharmaceutical; Drug Carriers; Edema; Emulsions; Gels; Inflammation; Male; Nanoparticles; Olive Oil; Pain; Rabbits; Rats; Rats, Wistar; Skin Absorption | 2019 |
Acute stress regulates nociception and inflammatory response induced by bee venom in rats: possible mechanisms.
Topics: Animals; Bee Venoms; Capsaicin; Disease Models, Animal; Edema; Hindlimb; Hyperalgesia; Inflammation; Male; Naloxone; Nociception; Oxidopamine; Pain; Rats; Rats, Sprague-Dawley; Restraint, Physical; Sciatic Nerve; Stress, Psychological; Sympathetic Nervous System | 2013 |
The anti-inflammatory effect of diclofenac is considerably augmented by topical capsaicinoids-containing patch in carrageenan-induced paw oedema of rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Capsicum; Carrageenan; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Fruit; Herb-Drug Interactions; Injections, Intramuscular; Injections, Subcutaneous; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Sensory System Agents; Transdermal Patch | 2013 |
Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Dextrans; Edema; Formaldehyde; Glutamic Acid; Histamine; Inflammation; Male; Mice; Naloxone; Pain; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Rats, Wistar; Sterculia | 2014 |
Antinociceptive and anti-inflammatory effects of flavonoids PMT1 and PMT2 isolated from Piper montealegreanum Yuncker (Piperaceae) in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Disease Models, Animal; Edema; Flavonoids; Formaldehyde; Male; Mice; Molecular Structure; Pain; Pain Measurement; Piper | 2014 |
Anti-inflammatory effects of Bryophyllum pinnatum (Lam.) Oken ethanol extract in acute and chronic cutaneous inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capsaicin; Chronic Disease; Croton Oil; Dermatitis, Contact; Edema; Ethanol; Ethnopharmacology; Kalanchoe; Male; Mice; Plant Extracts; Plant Leaves | 2014 |
Analgesic and anti-inflammatory effectiveness of sitagliptin and vildagliptin in mice.
Topics: Adamantane; Allyl Compounds; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Freund's Adjuvant; Isothiocyanates; Male; Mice; Nitriles; Pyrrolidines; Sitagliptin Phosphate; Temperature; Urinary Bladder; Vildagliptin | 2014 |
Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Capsaicin; Disease Models, Animal; Diterpenes; Edema; Hindlimb; Hyperalgesia; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nociceptors; Pain Threshold; Peroxidase; Reactive Oxygen Species; Sensory System Agents; Somatostatin; Tarsus, Animal; TRPV Cation Channels; X-Ray Microtomography | 2015 |
Peripheral neurokinin-1 receptors contribute to kaolin-induced acute monoarthritis in rats.
Topics: Animals; Animals, Newborn; Antidiarrheals; Arthritis; Capsaicin; Cytokines; Disease Models, Animal; Edema; Enzyme Inhibitors; Hyperalgesia; Indomethacin; Kaolin; Knee Joint; Male; Pain Measurement; Peroxidase; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Synovial Fluid | 2015 |
Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Edema; Hyperalgesia; Knee Joint; Male; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Pain; Protein Precursors; Receptor, PAR-2; Receptors, Neurokinin-1; Substance P; Tachykinins; Touch; TRPV Cation Channels; Tryptases | 2016 |
Functional depletion of capsaicin-sensitive primary afferent fibers attenuates rat pain-related behaviors and paw edema induced by the venom of scorpion Buthus martensi Karch.
Topics: Animals; Capsaicin; Diterpenes; Edema; Hindlimb; Hyperalgesia; Immunohistochemistry; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Spinal Cord | 2008 |
Lack of anti-inflammatory effect of botulinum toxin type A in experimental models of inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Capsaicin; Carrageenan; Disease Models, Animal; Edema; Inflammation Mediators; Male; Rats; Rats, Wistar | 2008 |
TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity.
Topics: Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Dermatitis, Contact; Dibutyl Phthalate; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Ganglia, Spinal; Gene Expression; Isothiocyanates; Mice; Mice, Inbred BALB C; Plasticizers; Rats; Sensory Receptor Cells; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2009 |
Tumor bearing decreases systemic acute inflammation in rats--role of mast cell degranulation.
Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Carrageenan; Cell Degranulation; Dextrans; Edema; Histamine; Inflammation; Mast Cells; Neoplasm Transplantation; Neoplasms; Neutrophil Activation; Neutrophil Infiltration; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Substance P | 2009 |
The role of the intensity of low frequency electroacupuncture stimulation on the modulation of capsaicin-induced edema in the rat paw. A blind controlled study.
Topics: Animals; Capsaicin; Disease Models, Animal; Edema; Electroacupuncture; Humans; Male; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Single-Blind Method | 2008 |
The antinociceptive and anti-inflammatory activities of caulerpin, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Caulerpa; Dose-Response Relationship, Drug; Edema; Female; Formaldehyde; Indole Alkaloids; Indoles; Male; Mice; Pain; Peritonitis; Seaweed | 2009 |
Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Baccharis; Capsaicin; Dermatitis, Contact; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Ear; Edema; Male; Mice; Neutrophil Infiltration; Oleanolic Acid; Plant Leaves; Plant Preparations; Stigmasterol; Tetradecanoylphorbol Acetate | 2010 |
Synthesis and preliminary biological evaluation of capsaicin derivatives as potential analgesic drugs.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cell Line; Disease Models, Animal; Drug Design; Edema; Female; Humans; Male; Mice; Molecular Structure; Pain; Rats; Stereoisomerism; TRPV Cation Channels; Xylenes | 2010 |
The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice.
Topics: Acrolein; Administration, Topical; Animals; Blotting, Western; Capsaicin; Dermatitis, Contact; Edema; Male; Mice; Peroxidase; Skin; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2011 |
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
Topics: Acrylamides; Anilides; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antioxidants; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cinnamates; Cromolyn Sodium; Disease Models, Animal; Diterpenes; Edema; Gabexate; Histamine; Male; Mast Cells; Methysergide; Pain; Promethazine; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Serotonin; Serotonin Antagonists; Tritium; TRPV Cation Channels; Uric Acid | 2011 |
Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms.
Topics: Acetic Acid; Analgesics; Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Antisickling Agents; Capsaicin; Colic; Drug Design; Ear; Edema; Female; Male; Mice; Mice, Transgenic; Models, Chemical; Molecular Structure; Peritonitis; Thalidomide; Thioglycolates; Tumor Necrosis Factor-alpha | 2011 |
Increased central and peripheral inflammation and inflammatory hyperalgesia in Zucker rat model of leptin receptor deficiency and genetic obesity.
Topics: Adiponectin; Animals; Capsaicin; Carrageenan; Down-Regulation; Edema; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Morphine; Nitric Oxide Synthase Type II; Nociception; Obesity; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Zucker; Receptors, Leptin; RNA, Messenger; Spinal Cord; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature.
Topics: Analgesics; Animals; Body Temperature; Bronchoconstriction; Capsaicin; Edema; Female; Hyperalgesia; Hypothermia; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Respiratory System; Sciatic Nerve; TRPV Cation Channels | 2012 |
Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties.
Topics: Analgesics; Animals; Binding, Competitive; Body Temperature; Calcium; Capsaicin; Chromatography, High Pressure Liquid; Diterpenes; Edema; Freund's Adjuvant; Hot Temperature; Male; Mice; Nociceptors; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Stigmasterol; Tissue Distribution; TRPV Cation Channels; Vernonia | 2012 |
Role of C-fibers during acute and chronic stress on formalin-induced paw edema in rats.
Topics: Animals; Capsaicin; Dexamethasone; Edema; Formaldehyde; Inflammation; Male; Nerve Fibers, Unmyelinated; Rats; Rats, Wistar; Stress, Physiological; Swimming | 2012 |
Anatomical and functional characterization of a duodeno-pancreatic neural reflex that can induce acute pancreatitis.
Topics: Acute Disease; Animals; Capsaicin; Central Nervous System Depressants; Diterpenes; Duodenum; Edema; Ethanol; Fluorescent Antibody Technique; Ganglia, Spinal; Male; Muscle Contraction; Pancreas; Pancreatitis; Patch-Clamp Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reflex; Sensory Receptor Cells; Splanchnic Nerves; Stomach; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2013 |
Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist.
Topics: Administration, Oral; Allergens; Animals; Butanols; Capsaicin; Cats; Dogs; Edema; Ferrets; Gerbillinae; Guinea Pigs; Histamine; Kinetics; Malates; Mice; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Platelet Activating Factor; Rabbits; Receptors, Neurokinin-1; Salivation; Substance P; Time Factors | 2002 |
Acupuncture modulation of capsaicin-induced inflammation: effect of intraperitoneal and local administration of naloxone in rats. A blinded controlled study.
Topics: Animals; Capsaicin; Edema; Electroacupuncture; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Neurogenic Inflammation; Random Allocation; Rats; Rats, Sprague-Dawley; Single-Blind Method | 2002 |
Spontaneous remission of edema and regranulation of goblet cells in rat tracheae after capsaicin-induced acute inflammation.
Topics: Acute Disease; Animals; Capsaicin; Cytoplasmic Granules; Disease Models, Animal; Edema; Goblet Cells; Mucus; Rats; Rats, Sprague-Dawley; Recovery of Function; Remission, Spontaneous; Trachea; Tracheitis | 2003 |
The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice.
Topics: Animals; Benzamides; Bradykinin Receptor Antagonists; Calcitonin Gene-Related Peptide; Capsaicin; Dipeptides; Edema; Foot; Glutamic Acid; Indoles; Male; Mice; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Piperidines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Neurokinin-2 | 2003 |
Peripheral tackykinin and excitatory amino acid receptors mediate hyperalgesia induced by Phoneutria nigriventer venom.
Topics: Animals; Capsaicin; Edema; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hindlimb; Hyperalgesia; Male; Pain Threshold; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Spider Venoms | 2003 |
Evaluation of the anti-inflammatory, anti-nociceptive and gastric effects of Ginkgo biloba in the rat.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Edema; Foot; Formaldehyde; Gastric Acid; Ginkgo biloba; Injections, Subcutaneous; Melatonin; Pain Measurement; Plant Extracts; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Time Factors | 2004 |
Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Ear; Edema; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Neurokinin-1 Receptor Antagonists; Piperidines; Plant Extracts; Plant Oils; Quinuclidines; Receptors, Drug; Receptors, Neurokinin-1; Staining and Labeling; Time Factors; TRPV Cation Channels | 2004 |
Capsaicin-induced joint inflammation is not blocked by local anesthesia.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Bupivacaine; Capsaicin; Dose-Response Relationship, Drug; Edema; Electromyography; Irritants; Male; Masseter Muscle; Neck Muscles; Neural Conduction; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Reflex, Stretch; Temporomandibular Joint | 2004 |
Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2005 |
Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats.
Topics: Action Potentials; Alanine; Animals; Capsaicin; Drug Interactions; Edema; Extremities; GABA Plasma Membrane Transport Proteins; Hyperalgesia; Injections, Intradermal; Laminectomy; Male; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Fibers, Unmyelinated; Neural Conduction; Neural Inhibition; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reflex; Skin; Spinal Nerve Roots; Time Factors | 2005 |
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.
Topics: Acute Disease; Analgesics; Animals; Capsaicin; Carrageenan; Chronic Disease; Dose-Response Relationship, Drug; Edema; Formaldehyde; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Isoquinolines; Ligation; Male; Motor Activity; Osteoarthritis; Pain; Pain Measurement; Pain, Postoperative; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sciatic Nerve; Spinal Nerves; Urea | 2005 |
Substance P does not play a critical role in neurogenic inflammation in the rat masseter muscle.
Topics: Analgesics; Animals; Capsaicin; Disease Models, Animal; Edema; Inflammation Mediators; Male; Masseter Muscle; Mustard Plant; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Plant Extracts; Plant Oils; Pyrrolidonecarboxylic Acid; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P | 2005 |
Anti-inflammatory, antinociceptive, and gastric effects of Hypericum perforatum in rats.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Drug Evaluation, Preclinical; Edema; Electroshock; Etodolac; Fluoxetine; Gastric Acid; Gastric Mucosa; Hot Temperature; Hypericum; Indomethacin; Pain; Peritonitis; Plant Extracts; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Stomach Ulcer | 2005 |
12-Acetoxyhawtriwaic acid lactone, a diterpene from Egletes viscosa, attenuates capsaicin-induced ear edema and hindpaw nociception in mice: possible mechanisms.
Topics: Analgesics; Animals; Asteraceae; Capsaicin; Diterpenes; Diterpenes, Clerodane; Ear; Edema; Flowers; Glyburide; Hindlimb; Lactones; Male; Mice; Naloxone; Nociceptors; Substance P; Theophylline; TRPV Cation Channels | 2006 |
Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.
Topics: Actins; Animals; Animals, Newborn; Blotting, Western; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Edema; Enzyme Inhibitors; Foot; GTP-Binding Proteins; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein Kinase C; Receptors, Prostaglandin E; Signal Transduction | 2006 |
Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Capsaicin; Chromatography, High Pressure Liquid; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Edema; Endocannabinoids; Formaldehyde; Ibuprofen; Lactones; Male; Mass Spectrometry; Nitrobenzenes; Pain Measurement; Peripheral Nervous System; Polyunsaturated Alkamides; Rats; Rats, Wistar; Sulfonamides; Sulfones; TRPV Cation Channels | 2006 |
Antinociceptive properties of diphenyl diselenide: evidences for the mechanism of action.
Topics: Acetic Acid; Analgesics; Animals; Benzene Derivatives; Bradykinin; Capsaicin; Edema; Female; Glutamates; Hindlimb; Hot Temperature; Lethal Dose 50; Male; Mice; Organoselenium Compounds; Pain | 2007 |
Roles of capsaicin-sensitive primary afferents in differential rat models of inflammatory pain: a systematic comparative study in conscious rats.
Topics: Analgesics, Non-Narcotic; Animals; Bee Venoms; Behavior, Animal; Capsaicin; Carrageenan; Edema; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Subcutaneous; Irritants; Male; Neuralgia; Neuritis; Neurons, Afferent; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time | 2007 |
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Topics: Animals; Aprotinin; Calcium Signaling; Capsaicin; Edema; Enteropeptidase; Ganglia, Spinal; Granulocytes; Humans; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptor, PAR-2; Receptors, Proteinase-Activated; Receptors, Thrombin; Recombinant Proteins; Trypsin; Trypsin Inhibitors | 2007 |
Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat.
Topics: Acute Disease; Animals; Capsaicin; Carrageenan; Diterpenes; Edema; Inflammation; Injections, Intraperitoneal; Male; Mass Spectrometry; Neurogenic Inflammation; Pituitary Adenylate Cyclase-Activating Polypeptide; Radioimmunoassay; Rats; Rats, Wistar; TRPV Cation Channels | 2007 |
Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin.
Topics: Analgesics; Animals; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Edema; GABA Antagonists; Injections, Intradermal; Neurogenic Inflammation; Peptide Fragments; Rats; Receptors, Neurokinin-1; Reflex; Spinal Nerve Roots; Substance P; TRPV Cation Channels; Vasodilation | 2007 |
Evidence for the involvement of glutamatergic and GABAergic systems and protein kinase A pathway in the antinociceptive effect caused by p-methoxy-diphenyl diselenide in mice.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetic Acid; Analgesics; Animals; Benzene Derivatives; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Edema; Enzyme Activators; Excitatory Amino Acids; Female; Formaldehyde; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; Immersion; Injections, Spinal; Mice; Motor Activity; Organoselenium Compounds; Pain; Reaction Time; Signal Transduction | 2008 |
Cardiac oxidative stress and electrophysiological changes in rats exposed to concentrated ambient particles are mediated by TRP-dependent pulmonary reflexes.
Topics: Action Potentials; Air Pollutants; Animals; Autonomic Nervous System; Capsaicin; Drug Interactions; Edema; Edema, Cardiac; Heart Diseases; Heart Rate; Inhalation Exposure; Lipid Peroxidation; Oxidative Stress; Particle Size; Particulate Matter; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2008 |
Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia.
Topics: Administration, Cutaneous; Animals; Behavior, Animal; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Edema; Electric Stimulation; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Inflammation; Male; Neurogenic Inflammation; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Sciatic Nerve; Time Factors; TRPV Cation Channels | 2008 |
Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclophosphamide; Cystitis; Edema; Glyburide; KATP Channels; Male; Mice; Oleanolic Acid; Pain; Receptors, Neurokinin-1; TRPV Cation Channels; Urinary Bladder | 2007 |
Topical acetone treatment induces neurogenic oedema on the sensitized mouse ear: an in vivo study using transient receptor potential vanilloid 1 (TRPV1) receptor knockout mice.
Topics: Acetone; Administration, Cutaneous; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Capsaicin; Diterpenes; Drug Synergism; Ear; Edema; Ibuprofen; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peroxidase; Sensory Receptor Cells; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Capsaicin; Capsicum; Carrageenan; Cell Movement; Edema; Exudates and Transudates; Inflammation; Interleukin-1beta; L-Lactate Dehydrogenase; Leukocytes; Male; Mice; Mice, Inbred C57BL; Peritonitis; Phytotherapy; Plant Preparations; Pleurisy; Rats; Rats, Wistar; Serum Albumin, Bovine; Tumor Necrosis Factor-alpha | 2008 |
Inflammatory peptide in spinal cord: evidence that the mediator of antidromic vasodilatation is not substance P.
Topics: Afferent Pathways; Animals; Animals, Newborn; Biological Assay; Capsaicin; Cattle; Edema; Guinea Pigs; Ileum; Peptides; Rats; Spinal Cord; Substance P; Vasodilation | 1980 |
Cigarette smoke-induced airway oedema due to activation of capsaicin-sensitive vagal afferents and substance P release.
Topics: Afferent Pathways; Animals; Capillary Permeability; Capsaicin; Edema; Male; Microscopy, Fluorescence; Rats; Rats, Inbred Strains; Respiratory System; Respiratory Tract Diseases; Smoking; Substance P; Synaptic Transmission; Vagus Nerve | 1983 |
Substance P in sensory nerve fibres contributes to the development of oedema in the rat hind paw after thermal injury.
Topics: Animals; Blood Proteins; Burns; Capsaicin; Edema; Evans Blue; Female; Hindlimb; Male; Nerve Tissue Proteins; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Temperature; Time Factors | 1984 |
Inhibition of cigarette smoke-induced oedema in the nasal mucosa by capsaicin pretreatment and a substance P antagonist.
Topics: Animals; Blood Pressure; Capillary Permeability; Capsaicin; Carbon Monoxide; Edema; Histamine Antagonists; Male; Nasal Mucosa; Nicotine; Rats; Rats, Inbred Strains; Smoking; Substance P | 1984 |
Effect of neonatal treatment with capsaicin on carrageenan-induced paw oedema in the rat.
Topics: Animals; Animals, Newborn; Capsaicin; Carrageenan; Edema; Histamine Release; Indomethacin; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Capsaicin pretreatment inhibits heat-induced oedema in the rat skin.
Topics: Animals; Burns; Capillary Permeability; Capsaicin; Edema; Hot Temperature; Rats; Rats, Inbred Strains; Skin; Vasodilation | 1983 |
Capsaicin pretreatment abolishes cigarette smoke-induced oedema in rat tracheo-bronchial mucosa.
Topics: Animals; Capillary Permeability; Capsaicin; Edema; Fatty Acids, Unsaturated; In Vitro Techniques; Mucous Membrane; Nicotine; Rats; Rats, Inbred Strains; Respiratory System; Smoking; Spectrometry, Fluorescence | 1982 |
Pharmacology of the neurogenic oedema response to electrical stimulation of the saphenous nerve in the rat.
Topics: Amines; Animals; Bacitracin; Blood Pressure; Capsaicin; Edema; Electric Stimulation; Leg; Male; Mast Cells; Morphine; Neurons, Afferent; Rats | 1980 |
Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.
Topics: Administration, Cutaneous; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cyproheptadine; Edema; Indomethacin; Male; Mice; Neuropeptides; Nifedipine; Substance P | 1993 |
Anti-edema action of formoterol in rat trachea does not depend on capsaicin-sensitive sensory nerves.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Afferent Pathways; Animals; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Endothelium, Vascular; Ethanolamines; Formoterol Fumarate; Injections, Intravenous; Male; Platelet Activating Factor; Premedication; Rats; Rats, Inbred F344; Substance P; Trachea; Tracheal Diseases | 1994 |
Modulation of carrageenan-induced hind paw edema by substance P.
Topics: Animals; Capsaicin; Carrageenan; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Foot; Organ Size; Rats; Rats, Sprague-Dawley; Substance P | 1994 |
Anti-oedematous action of some H1-receptor antagonists.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Croton Oil; Dextrans; Dimethindene; Ear, External; Edema; Foot; Histamine H1 Antagonists; Male; Mice; Mice, Inbred Strains; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar | 1994 |
An investigation into the mechanism of capsaicin-induced oedema in rabbit skin.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Catalase; Dexamethasone; Drug Interactions; Edema; Histamine; Indoles; Indomethacin; Injections, Intradermal; Injections, Intravenous; Isoindoles; Male; Piperidines; Rabbits; Regional Blood Flow; Ruthenium Red; Skin; Substance P; Vasodilator Agents | 1995 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
Histamine-induced edema in the rat paw--effect of capsaicin denervation and a CGRP receptor antagonist.
Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capillary Permeability; Capsaicin; Denervation; Edema; Foot; Histamine; Male; Miotics; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley | 1995 |
Participation of nitric oxide in the mustard oil-induced neurogenic inflammation of the rat paw skin.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Capsaicin; Dermatitis; Edema; Female; Mustard Plant; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Serum Albumin; Skin; Thermography | 1993 |
A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hypertonic Solutions; Neurokinin A; Neurons, Afferent; Piperidines; Platelet Activating Factor; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Sodium Chloride; Stimulation, Chemical; Substance P; Trachea; Tracheal Diseases | 1993 |
The pharmacological properties of FK888, a novel dipeptide NK1 antagonist.
Topics: Animals; Bronchoconstriction; Capsaicin; Cell Membrane; Dipeptides; Edema; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indoles; Kinetics; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-1; Substance P | 1993 |
Mediation by bradykinin of rat paw oedema induced by collagenase from Clostridium histolyticum.
Topics: Animals; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Edema; Female; Foot; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypnotics and Sedatives; Microbial Collagenase; Motor Activity; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 1994 |
Mucosal exudation associated with a pulmonary delayed-type hypersensitivity reaction in the mouse. Role for the tachykinins.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Edema; Exudates and Transudates; Hypersensitivity, Delayed; Indoles; Isoindoles; Lung; Male; Mice; Mice, Inbred BALB C; Mucous Membrane; Peptide Fragments; Tachykinins | 1994 |
Effect of a calcitonin gene-related peptide antagonist (CGRP8-37) on skin vasodilatation and oedema induced by stimulation of the rat saphenous nerve.
Topics: Alprostadil; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Edema; Electric Stimulation; Epoprostenol; Hindlimb; Laser-Doppler Flowmetry; Male; Neurons, Afferent; Peptide Fragments; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Skin; Vasodilation | 1993 |
Capsaicin-induced flare and vasodilatation in patients with post-herpetic neuralgia.
Topics: Administration, Topical; Afferent Pathways; Aged; Axons; Capsaicin; Case-Control Studies; Edema; Female; Herpes Zoster; Humans; Male; Middle Aged; Nerve Fibers; Neuralgia; Nociceptors; Pain Threshold; Vasodilator Agents | 1995 |
Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema.
Topics: Animals; Capillary Permeability; Capsaicin; Ear Diseases; Edema; Male; Mice; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachyphylaxis | 1995 |
Intraplantar injection of nerve growth factor into the rat hind paw: local edema and effects on thermal nociceptive threshold.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase Inhibitors; Denervation; Edema; Foot; Histamine; Injections; Male; Mast Cells; Nerve Growth Factors; Neurons, Afferent; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Substance P | 1996 |
Effects of prostaglandin antagonist phloretin derivatives on mouse ear edema induced with different skin irritants.
Topics: Animals; Anthralin; Arachidonic Acid; Capsaicin; Croton Oil; Ear; Edema; Irritants; Male; Mice; Mice, Inbred Strains; Polyphloretin Phosphate; Prostaglandin Antagonists | 1995 |
Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema.
Topics: Animals; Binding Sites; Capsaicin; Dipeptides; Disease Models, Animal; Ear Diseases; Edema; Indoles; Injections, Intravenous; Lethal Dose 50; Male; Mice; Piperidines; Quinuclidines; Receptors, Tachykinin; Skin; Stereoisomerism; Structure-Activity Relationship; Substance P | 1996 |
Participation of serotonin in capsaicin-induced mouse ear edema.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Capsaicin; Ear Diseases; Edema; Male; Mice; Mice, Inbred Strains; Serotonin; Substance P | 1995 |
Inhibitory effect of glycyrrhetinic acid derivatives on capsaicin-induced ear edema in mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Capsaicin; Dose-Response Relationship, Drug; Edema; Glycyrrhetinic Acid; Linear Models; Male; Mice; Mice, Inbred Strains; Substance P | 1996 |
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P | 1996 |
Effects of neurokinin depletion on airway inflammation induced by chronic antigen exposure.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Antigens; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; CD4 Lymphocyte Count; Edema; Elasticity; Guinea Pigs; Inflammation; Lung; Lung Compliance; Male; Ovalbumin; Tachykinins | 1997 |
Mechanism of mustard oil-induced skin inflammation in mice.
Topics: Administration, Topical; Animals; Capillary Permeability; Capsaicin; Dermatitis; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Histamine H1 Antagonists; Indicators and Reagents; Male; Mast Cells; Mice; Mustard Plant; Plant Extracts; Plant Oils; Plants, Medicinal; Protease Inhibitors; Receptors, Tachykinin; Ruthenium Red; Serotonin Antagonists | 1997 |
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles | 1997 |
Phoneutria nigriventer spider venom induces oedema in rat skin by activation of capsaicin sensitive sensory nerves.
Topics: Animals; Animals, Newborn; Blood Pressure; Blood Proteins; Capsaicin; Edema; Female; Male; Nervous System; Rats; Rats, Wistar; Receptors, Tachykinin; Skin Diseases; Spider Venoms; Spiders | 1997 |
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Carrageenan; Edema; Endocannabinoids; Hindlimb; Hyperalgesia; Male; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Skin | 1998 |
A possible role of nitric oxide formation in the vasodilatation of rabbit ear artery induced by a topically applied Capsaicin analogue.
Topics: Administration, Topical; Animals; Arteries; Capsaicin; Dose-Response Relationship, Drug; Ear; Edema; Enzyme Inhibitors; Female; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Vasodilation | 1998 |
Vespula vulgaris venom: role of kinins and release of 5-hydroxytryptamine from skin mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Edema; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Injections, Intravenous; Injections, Subcutaneous; Kinins; Mast Cells; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Serotonin; Serotonin Antagonists; Skin; Wasp Venoms | 1998 |
Effects of deep vs. superficial stimulation of acupuncture on capsaicin-induced edema. A blind controlled study in rats.
Topics: Acupuncture Therapy; Animals; Capsaicin; Disease Models, Animal; Edema; Humans; Male; Rats; Rats, Sprague-Dawley; Single-Blind Method | 1998 |
Systemic anti-inflammatory effect induced by counter-irritation through a local release of somatostatin from nociceptors.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Dextrans; Edema; Female; Inflammation; Rats; Rats, Wistar; Sensory Receptor Cells; Somatostatin | 1998 |
Unilateral injection of calcitonin gene-related peptide (CGRP) induces bilateral oedema formation and release of CGRP-like immunoreactivity in the rat hindpaw.
Topics: Animals; Bicuculline; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Chromatography, High Pressure Liquid; Drug Interactions; Edema; GABA Antagonists; Hindlimb; Histamine Antagonists; Humans; Male; Miotics; Peptide Fragments; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Thiorphan | 1998 |
Effects of cinnarizine on different experimentally induced oedemas.
Topics: Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Blood Pressure; Calcium Channel Blockers; Capsaicin; Carrageenan; Cinnarizine; Croton Oil; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ear; Edema; Excipients; Foot; Hindlimb; Injections, Intraperitoneal; Irritants; Male; Mice; Rats; Rats, Wistar | 1999 |
Analgesic effect of subcutaneous administration of oxygen-ozone. A blind study in the rat on the modulation of the capsaicin-induced edema.
Topics: Acupuncture Analgesia; Animals; Capsaicin; Disease Models, Animal; Edema; Injections, Subcutaneous; Male; Neurogenic Inflammation; Oxygen; Ozone; Rats; Rats, Sprague-Dawley | 1998 |
The inflammatory reaction induced by formalin in the rat paw.
Topics: Anesthetics, Local; Animals; Blood Pressure; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Inflammation Mediators; Kininogens; Lidocaine; Male; Neuropeptides; Rats; Rats, Wistar; Serum Albumin; Time Factors | 1999 |
Use of NK(1) knockout mice to analyze substance P-induced edema formation.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Edema; Female; Histamine H1 Antagonists; Injections, Intradermal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; p-Methoxy-N-methylphenethylamine; Pyrilamine; Receptors, Neurokinin-1; Skin Diseases; Substance P; Tachykinins | 1999 |
Oral antinociception and oedema inhibition produced by NPC 18884, a non-peptidic bradykinin B2 receptor antagonist.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Behavior, Animal; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Carrageenan; Dinoprostone; Dipeptides; Dose-Response Relationship, Drug; Edema; Formaldehyde; Hindlimb; Hyperalgesia; Injections, Intraperitoneal; Male; Mice; Pain; Rats; Rats, Wistar; Receptor, Bradykinin B2; Time Factors | 1999 |
Studies on the anti-inflammatory and analgesic activity of Curatella americana L.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Brazil; Capsaicin; Carcinogens; Dose-Response Relationship, Drug; Edema; Indicators and Reagents; Lethal Dose 50; Male; Medicine, Traditional; Mice; Plant Extracts; Rats; Rats, Wistar; Stereotyped Behavior; Tetradecanoylphorbol Acetate | 1999 |
Endothelin-1-induced ET(A) receptor-mediated nociception, hyperalgesia and oedema in the mouse hind-paw: modulation by simultaneous ET(B) receptor activation.
Topics: Animals; Atrasentan; Capsaicin; Edema; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hyperalgesia; Male; Mice; Nociceptors; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Piperidines; Pyrrolidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Viper Venoms | 2000 |
The role of sensorial neuropeptides in the edematogenic responses mediated by B(1) agonist des-Arg(9)-BK in rats pre-treated with LPS.
Topics: Animals; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Edema; Histamine H1 Antagonists; Lipopolysaccharides; Male; Methysergide; Mianserin; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Piperidines; Pyrazoles; Pyridines; Pyrilamine; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptors, Bradykinin; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Serotonin Antagonists | 2000 |
Involvement of mast cells, sensory afferents and sympathetic mechanisms in paw oedema induced by adenosine A(1) and A(2B/3) receptor agonists.
Topics: Adenosine; Animals; Capsaicin; Dose-Response Relationship, Drug; Edema; Hindlimb; Male; Mast Cells; Neurons, Afferent; Oxidopamine; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptor, Adenosine A3; Sympathetic Nervous System; Sympatholytics | 2000 |
Involvement of kinins, mast cells and sensory neurons in the plasma exudation and paw oedema induced by staphylococcal enterotoxin B in the mouse.
Topics: Animals; Benzamides; Bradykinin; Capillary Permeability; Capsaicin; Diabetes Mellitus, Experimental; Edema; Enterotoxins; Hindlimb; Kinins; Male; Mast Cells; Mice; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Pyrilamine; Quinuclidines; Receptors, Neurokinin-2 | 2000 |
Effect of ricinoleic acid in acute and subchronic experimental models of inflammation.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Chronic Disease; Disease Models, Animal; Edema; Eyelid Diseases; Eyelids; Freund's Adjuvant; Guinea Pigs; Histamine; Injections, Intradermal; Male; Ricinoleic Acids | 2000 |
Comparative effect of Phoneutria nigriventer spider venom and capsaicin on the rat paw oedema.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Edema; Female; Foot; Histamine H1 Antagonists; Indicators and Reagents; Male; Mast Cells; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; p-Methoxy-N-methylphenethylamine; Piperidines; Quinuclidines; Rats; Rats, Wistar; Spider Venoms | 2001 |
Lack of a significant effect of deletion of the tachykinin neurokinin-1 receptor on wound healing in mouse skin.
Topics: Animals; Capsaicin; Edema; Gene Deletion; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Neurokinin-1; Skin; Substance P; Sutures; Wound Healing | 2001 |
Interactive contribution of NK(1) and kinin receptors to the acute inflammatory oedema observed in response to noxious heat stimulation: studies in NK(1) receptor knockout mice.
Topics: Administration, Topical; Animals; Bradykinin; Bradykinin Receptor Antagonists; Burns; Capsaicin; Cell Movement; Dermatitis; Edema; Hot Temperature; Injections, Intravenous; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Piperidines; Quinuclidines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Neurokinin-1; Tachykinins; Time Factors | 2001 |
Capsaicin sensitive afferents mediate the development of heat hyperalgesia and hindpaw edema after sciatic section in rats.
Topics: Animals; Animals, Newborn; Capsaicin; Coloring Agents; Complex Regional Pain Syndromes; Denervation; Disease Models, Animal; Edema; Electric Stimulation; Hindlimb; Hyperalgesia; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2002 |
ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation.
Topics: Animals; Benzoquinones; Binding Sites; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels; Capsaicin; Carrageenan; Central Nervous System; CHO Cells; Cricetinae; Disease Models, Animal; Edema; Extravasation of Diagnostic and Therapeutic Materials; Gene Expression; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Mice; Neurogenic Inflammation; Pain; Pain Measurement; Piperidines; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Species Specificity; Spinal Cord; Transfection; Tritium | 2002 |
Modification by capsaicin and compound 48/80 of dye leakage induced by irritants in the rat.
Topics: Adenosine Triphosphate; Animals; Azo Compounds; Bradykinin; Capsaicin; Edema; Evans Blue; Fatty Acids, Unsaturated; Formaldehyde; Histamine; Hydrochloric Acid; Male; Models, Biological; p-Methoxy-N-methylphenethylamine; Potassium Chloride; Prostaglandins E; Rats; Serotonin; Skin | 1977 |
A study of chemically induced acute inflammation in the skin of the rat.
Topics: Animals; Benzene; Capsaicin; Cell Count; Ear; Edema; Inflammation; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Skin; Sympathetic Nervous System | 1977 |
Development and inhibition of mouse ear oedema induced with capsaicin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Ear Diseases; Ear, External; Edema; Histamine H1 Antagonists; Male; Mice | 1992 |
Substance P provokes cutaneous erythema and edema through a histamine-independent pathway.
Topics: Adult; Capsaicin; Edema; Erythema; Female; Histamine; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Substance P | 1992 |
Effects of FK224, a novel compound NK1 and NK2 receptor antagonist, on airway constriction and airway edema induced by neurokinins and sensory nerve stimulation in guinea pigs.
Topics: Animals; Bronchoconstriction; Capsaicin; Constriction, Pathologic; Edema; Guinea Pigs; Histamine Antagonists; Injections, Intravenous; Male; Peptides, Cyclic; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea | 1992 |
Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Edema; In Vitro Techniques; Inflammation; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1992 |
The partial inhibition of inflammatory responses induced by capsaicin using the Fab fragment of a selective calcitonin gene-related peptide antiserum in rabbit skin.
Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Edema; Immune Sera; Immunoglobulin Fab Fragments; Immunoglobulin G; Inflammation; Male; Rabbits; Skin | 1992 |
Neurogenic and tissue-mediated components of formalin-induced edema: evidence for supraspinal regulation.
Topics: Animals; Axons; Capsaicin; Denervation; Down-Regulation; Edema; Foot; Formaldehyde; Male; Nerve Block; Nervous System; Neurons, Afferent; Peripheral Nerves; Rats; Rats, Inbred Strains; Spinal Cord; Synaptic Transmission | 1991 |
Ruthenium red selectively inhibits oedema formation and increased blood flow induced by capsaicin in rabbit skin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Edema; Microcirculation; Rabbits; Regional Blood Flow; Ruthenium; Ruthenium Red; Skin | 1990 |
A bradykinin (BK)1 receptor antagonist blocks capsaicin-induced ear inflammation in mice.
Topics: Animals; Bradykinin; Capsaicin; Ear, External; Edema; Inflammation; Male; Mice; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P | 1990 |
[Participation of the sensory nerves in the inflammatory response induced by irritants].
Topics: Animals; Capillary Permeability; Capsaicin; Carnitine; Denervation; Edema; Irritants; Male; Mice; Neurons, Afferent; Rats; Rats, Inbred Strains; Sciatic Nerve; Substance P | 1990 |
Potent anti-inflammatory action of calcitonin gene-related peptide.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Cricetinae; Edema; Female; Histamine; Humans; Inflammation; Leukotriene B4; Male; Middle Aged; Mouth Mucosa; Rats; Serotonin; Skin; Skin Physiological Phenomena; Substance P | 1991 |
A calcitonin gene-related peptide (CGRP) antagonist (CGRP8-37) inhibits microvascular responses induced by CGRP and capsaicin in skin.
Topics: Alprostadil; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Drug Synergism; Edema; Histamine; Male; Microcirculation; Peptide Fragments; Rabbits; Serum Albumin, Radio-Iodinated; Skin; Vasodilator Agents; Xenon Radioisotopes | 1991 |
Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Capsaicin; Carrageenan; Cell Movement; Edema; Guinea Pigs; Inflammation; Leukocytes; Male; Mice; Otitis; Platelet Aggregation Inhibitors; Pleurisy; Rats; Rats, Inbred Strains; Vanillic Acid | 1990 |
Contribution of substance P to heat-induced edema in rat paw.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Edema; Histamine; Hot Temperature; Male; Pyridazines; Rats; Rats, Inbred Strains; Substance P | 1987 |
Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.
Topics: Animals; Capsaicin; Carbachol; Edema; Histamine; Male; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Skin Physiological Phenomena; SRS-A; Substance P; Trachea | 1989 |
Participation of substance P in inflammatory responses.
Topics: Animals; Capsaicin; Dactinomycin; Denervation; Dexamethasone; Edema; Hot Temperature; Inflammation; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Nerves; Substance P | 1989 |
Capsaicin sensitive afferents contribute to acute airway edema following tracheal instillation of hydrochloric acid or gastric juice in the rat.
Topics: Animals; Capsaicin; Edema; Gastric Acid; Male; Neurons, Afferent; Rats; Trachea; Tracheal Diseases | 1988 |
Effects of capsaicin pretreatment on the inflammatory response to scalding injury in the rat.
Topics: Animals; Burns; Capsaicin; Edema; Female; Neurons, Afferent; Rats; Rats, Inbred Strains; Skin; Time Factors | 1987 |
Sorbic acid-induced erythema and edema.
Topics: Administration, Topical; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Capsaicin; Cosmetics; Dermatitis, Atopic; Dose-Response Relationship, Drug; Edema; Erythema; Fatty Acids, Unsaturated; Histamine; Humans; Hydrocortisone; Hydroxyzine; Lidocaine; Mast Cells; Pharmaceutic Aids; Preservatives, Pharmaceutical; Sorbic Acid | 1986 |