capsaicin has been researched along with Chronic Pain in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 32 (60.38) | 24.3611 |
| 2020's | 21 (39.62) | 2.80 |
| Authors | Studies |
|---|---|
| Callaway, E; Ledford, H | 1 |
| Arora, V; Asgar, J; Chung, MK; Kumari, S; Li, T; Wang, S | 1 |
| Goto, S; Haji, A; Kodama, D; Miyazawa, K; Ohi, Y; Tamada, M | 1 |
| Clark, JD; Ferguson, AR; Irvine, KA; Peters, CM; Vazey, EM | 1 |
| Dorsey, SG; Greenspan, JD; Gullapalli, RP; Keaser, ML; Khan, SA; Meeker, TJ; Schmid, AC; Seminowicz, DA | 1 |
| Mickle, AD; Mohapatra, DP; Robilotto, GL; Shepherd, AJ | 1 |
| Abd El Hay, M; Chesler, AT; Lam, RM; Lu, S; Pohle, J; Rostock, C; Schrenk-Siemens, K; Siemens, J; Szczot, M | 1 |
| Alhajri, N; Boudreau, SA; Graven-Nielsen, T | 1 |
| Ishida, S; Kikuchi, K; Murata, M; Tagawa, Y | 1 |
| Forouzanfar, F; Pourbagher-Shahri, AM | 1 |
| Guo, J; Song, Y; Tang, J; Tang, Z; Yang, Y; Yu, G; Zhu, C | 1 |
| Koga, K; Uta, D; Yoshimura, M | 1 |
| Diatchenko, L; Echeverry, S; Millecamps, M; Piltonen, M; Shi, XQ; Stone, LS; Zhang, J | 1 |
| Clark, JD; Ferguson, AR; Irvine, KA; Sahbaie, P | 1 |
| Aleidi, SM; ALSalamat, HA; Awad, WB; Haddaden, RM; Issa, AY | 1 |
| Barbosa, P; Gomes, A; Goncalves, D; Rebelo, V | 1 |
| Arora, V; Campbell, JN; Chung, MK | 1 |
| Gašparini, D; Ljubičić, R; Mršić-Pelčić, J | 1 |
| Freeman, J; Gupta, R; Maloney, J; Pew, S; Strand, N; Wie, C | 1 |
| Anderson, T; Dodick, DW; Kopruszinski, CM; Navratilova, E; Porreca, F; Schwedt, TJ; Swiokla, J; Turnes, JM; Weinstein, TJ | 1 |
| Allison, C; John Z, S; Korey, L | 1 |
| Chung, JM; Hankerd, K; La, JH; McDonough, KE; Tang, SJ; Wang, J | 1 |
| Aldington, D; Bell, RF; Derry, S; Gaskell, H; Kalso, EA; Moore, RA; Phillips, T; Wiffen, PJ | 1 |
| Crawford, P; Xu, Y | 1 |
| Drewes, AM; Larsen, IM; Olesen, AE | 1 |
| Klumpp, DJ; Miller, RJ; Rosen, JM; Schaeffer, AJ; Woida, PJ; Yaggie, RE | 1 |
| Fischer, L; Lamana, MS; Miranda, J; Tambeli, CH; Tobaldini, G | 1 |
| Bjurstrom, MF; Finan, PH; Gonzalez, K; Irwin, MR; Remeniuk, B; Robinson, M; Smith, MT; Speed, TJ; Tompkins, DA | 1 |
| Azad, SC; Luchting, B | 1 |
| Abualnadi, N; Dizon, AM; Schiff, L | 1 |
| Chen, CC; Han, DS; Lee, CH; Shieh, YD | 1 |
| Dahan, A; Krebs-Brown, A; Martini, CH; Olofsen, E; Passier, P; Stoker, M; Yassen, A | 1 |
| Córdova, MM; Montrucchio, DP; Santos, AR | 1 |
| Carroll, I; Curtin, CM | 1 |
| Keavney, J; Murphy, K; O'Brien, J; Pollard, V; Weekes, G | 1 |
| Bhatnagar, A; Billeter, AT; Hellmann, JL; Polk, HC | 1 |
| Alayli, G; Durmus, D; Kuru, O; Tufekci, T | 1 |
| Alleyne, RT; LeBlanc, BW; Lii, TR; Saab, CY; Silverman, AE | 1 |
| Caterina, MJ; Chu, Y; Dong, X; Dubner, R; Han, L; Kim, YS; LaVinka, PC; Li, M; Li, Z; Park, K; Ren, K; Sun, S; Tang, Z; Wei, F | 1 |
| Anger, WH | 1 |
| Galluzzi, KE; Stanos, SP | 1 |
| Brown, SH; Hung, LY; Maracle, E; Srbely, JZ | 1 |
| Baker, DG; Moeller-Bertram, T; Patel, P; Schilling, JM; Simmons, AN; Strigo, IA | 1 |
| Ganev, EG; Hiruma-Lima, CA; Martins, DF; Mazzardo-Martins, L; Nishijima, CM; Rocha, LR; Santos, AR | 1 |
| Chen, CC; Chen, WN | 1 |
| Chichorro, JG; Hummig, W; Kopruszinski, CM | 1 |
| Athie, M; Dias, EV; Lamana, SM; Miranda, J; Parada, CA; Tambeli, CH | 1 |
| Charrua, A; Di Marzo, V; Martins, D; Morgado, C; Piscitelli, F; Silva, M; Tavares, I | 1 |
| Camponogara, C; Casoti, R; Chipindo, OJ; de Oliveira, SM; De Prá, SD; Ferreira, J; Ferro, PR; Manfron, MP; Milioli, AM; Rigo, FK; Trevisan, G | 1 |
| Cole, P; Derry, S; Moore, RA; Rice, AS; Tan, T | 1 |
| Derry, S; Moore, RA | 1 |
| Bean, BP; Brenneis, C; Cobos, EJ; Ferreirós, N; Geisslinger, G; Ghasemlou, N; Kistner, K; Labocha, S; Puopolo, M; Reeh, PW; Roberson, D; Segal, D; Sisignano, M; Strominger, A; Woolf, CJ | 1 |
| Alayli, G; Bilgici, A; Durmus, D; Goktepe, AS; Kuru, O; Taskaynatan, MA | 1 |
13 review(s) available for capsaicin and Chronic Pain
| Article | Year |
|---|---|
Saffron (Crocus sativus) and its constituents for pain management: A review of current evidence.
Topics: Analgesics; Arthritis, Rheumatoid; Biological Products; Capsaicin; Chronic Pain; Crocus; Plant Extracts | 2023 |
Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain.
Topics: Analgesia; Analgesics; Animals; Calpain; Capsaicin; Chronic Pain; Mice; Neuralgia; TRPV Cation Channels | 2021 |
Capsaicin - Potential Solution for Chronic Pain Treatment.
Topics: Analgesics; Capsaicin; Chronic Pain; Humans; Pain Management; Quality of Life | 2020 |
Comprehensive Review of Topical Analgesics for Chronic Pain.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Capsaicin; Chronic Pain; Humans; Lidocaine | 2021 |
Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews.
Topics: Acute Pain; Adult; Analgesics; Arthritis, Rheumatoid; Capsaicin; Chronic Pain; Diclofenac; Humans; Ketoprofen; Musculoskeletal Pain; Neuralgia; Numbers Needed To Treat; Osteoarthritis; Piroxicam; Publication Bias; Review Literature as Topic | 2017 |
Topical Capsaicin for Treatment of Chronic Neuropathic Pain in Adults.
Topics: Administration, Topical; Adult; Capsaicin; Chronic Pain; Evidence-Based Medicine; Humans; Neuralgia; Risk Assessment; Sensory System Agents | 2017 |
Pain therapy for the elderly patient: is opioid-free an option?
Topics: Administration, Topical; Age Factors; Aged; Aging; Analgesics, Non-Narcotic; Analgesics, Opioid; Capsaicin; Chronic Pain; Humans; Pain Management; Pain Measurement; Transdermal Patch; Treatment Outcome | 2019 |
Opioid Adjuncts: Optimizing Opioid Therapy With Nonopioid Medications.
Topics: Acetaminophen; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Capsaicin; Chemotherapy, Adjuvant; Chronic Pain; Female; Humans; Muscle Relaxants, Central; Pain Management; Receptors, N-Methyl-D-Aspartate; Serotonin and Noradrenaline Reuptake Inhibitors | 2019 |
Management of chronic pain following nerve injuries/CRPS type II.
Topics: Amines; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Capsaicin; Causalgia; Chronic Pain; Cyclohexanecarboxylic Acids; Diphosphonates; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Block; Peripheral Nerve Injuries; Sensory System Agents; Terminology as Topic | 2013 |
Transient receptor potential ion channels: powerful regulators of cell function.
Topics: Analgesics; Anti-Inflammatory Agents; Biomarkers; Calcium Channels; Capsaicin; Chronic Pain; Duloxetine Hydrochloride; Humans; Inflammation; Macrophages; Melanoma; Monocytes; Nerve Tissue Proteins; Pain, Postoperative; Respiratory Tract Diseases; Surgical Wound Infection; Thiophenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2014 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Pain; Diclofenac; Humans; Ibuprofen; Irritants; Ketoprofen; Lidocaine; Musculoskeletal Pain; Neoplasms; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis, Knee; Palliative Care | 2013 |
Topical capsaicin (high concentration) for chronic neuropathic pain in adults.
Topics: Administration, Topical; Adult; Analgesics; Capsaicin; Chronic Pain; Diabetic Neuropathies; HIV Infections; Humans; Neuralgia; Neuralgia, Postherpetic; Numbers Needed To Treat; Ointments; Pain, Postoperative; Randomized Controlled Trials as Topic | 2017 |
Topical capsaicin (low concentration) for chronic neuropathic pain in adults.
Topics: Administration, Topical; Adult; Capsaicin; Chronic Pain; Drug Administration Schedule; Humans; Neuralgia; Randomized Controlled Trials as Topic; Sensory System Agents | 2012 |
6 trial(s) available for capsaicin and Chronic Pain
| Article | Year |
|---|---|
A novel computational technique for the quantification of temporal summation in healthy individuals.
Topics: Capsaicin; Central Nervous System Sensitization; Chronic Pain; Humans; Hyperalgesia; Pain Measurement | 2021 |
The Effect of a Combination of Diclofenac and Methadone Applied as Gel in a Human Experimental Pain Model - A Randomized, Placebo-controlled Trial.
Topics: Administration, Cutaneous; Adult; Capsaicin; Chronic Pain; Cross-Over Studies; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Gels; Healthy Volunteers; Humans; Hyperalgesia; Injections, Intradermal; Male; Methadone; Middle Aged; Nerve Growth Factor; Pain Measurement; Placebos; Treatment Outcome; Young Adult | 2018 |
A novel approach to identify responder subgroups and predictors of response to low- and high-dose capsaicin patches in postherpetic neuralgia.
Topics: Aged; Aged, 80 and over; Capsaicin; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Neuralgia, Postherpetic; Transdermal Patch; Treatment Outcome | 2013 |
A randomized placebo-controlled clinical trial of phonophoresis for the treatment of chronic neck pain.
Topics: Analgesics; Capsaicin; Chronic Pain; Combined Modality Therapy; Depression; Disability Evaluation; Exercise Therapy; Female; Humans; Neck Pain; Pain Measurement; Phonophoresis; Prospective Studies; Single-Blind Method; Sleep; Surveys and Questionnaires; Time Factors; Treatment Outcome; Turkey | 2014 |
Acute experimentally induced neck pain does not affect fatigability of the peripheral biceps brachii muscle.
Topics: Adult; Arm; Capsaicin; Chronic Pain; Elbow; Elbow Joint; Electromyography; Fatigue; Humans; Isometric Contraction; Male; Muscle Fatigue; Muscle, Skeletal; Neck Pain; Pain; Young Adult | 2014 |
Is phonophoresis effective in the treatment of chronic low back pain? A single-blind randomized controlled trial.
Topics: Adult; Analgesics; Analysis of Variance; Biomechanical Phenomena; Capsaicin; Chi-Square Distribution; Chronic Pain; Combined Modality Therapy; Disability Evaluation; Exercise Test; Exercise Therapy; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Strength; Pain Measurement; Pain Perception; Pain Threshold; Phonophoresis; Predictive Value of Tests; Prospective Studies; Quality of Life; Range of Motion, Articular; Recovery of Function; Single-Blind Method; Spine; Time Factors; Treatment Outcome; Turkey; Ultrasonic Therapy; Walking | 2013 |
34 other study(ies) available for capsaicin and Chronic Pain
| Article | Year |
|---|---|
Medicine Nobel goes to scientists who discovered biology of senses.
Topics: Biomedical Research; Capsaicin; Chronic Pain; Hot Temperature; Ion Channels; Nobel Prize; Research Personnel; Thermosensing; Touch; TRPM Cation Channels; TRPV Cation Channels | 2021 |
Capsaicin-induced depolymerization of axonal microtubules mediates analgesia for trigeminal neuropathic pain.
Topics: Animals; Capsaicin; Chronic Pain; Hyperalgesia; Mice; Microtubules; Neuralgia; Paclitaxel; Trigeminal Neuralgia; TRPV Cation Channels; Tubulin | 2022 |
Modulation of excitatory synaptic transmissions by TRPV1 in the spinal trigeminal subnucleus caudalis neurons of neuropathic pain rats.
Topics: Animals; Capsaicin; Chronic Pain; Disease Models, Animal; Excitatory Postsynaptic Potentials; Facial Pain; Humans; Male; Neuralgia; Neurons; Rats; Synaptic Transmission; Trigeminal Caudal Nucleus; TRPV Cation Channels | 2021 |
Activation of the Locus Coeruleus Mediated by Designer Receptor Exclusively Activated by Designer Drug Restores Descending Nociceptive Inhibition after Traumatic Brain Injury in Rats.
Topics: Adrenergic Antagonists; Animals; Brain Injuries, Traumatic; Capsaicin; Chronic Pain; Designer Drugs; Locus Coeruleus; Nociception; Rats | 2022 |
Tonic pain alters functional connectivity of the descending pain modulatory network involving amygdala, periaqueductal gray, parabrachial nucleus and anterior cingulate cortex.
Topics: Amygdala; Brain Mapping; Capsaicin; Chronic Pain; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Parabrachial Nucleus; Periaqueductal Gray | 2022 |
Role of Src kinase in regulating protein kinase C mediated phosphorylation of TRPV1.
Topics: Animals; Calcium; Capsaicin; Chronic Pain; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Mice; Phosphorylation; Protein Kinase C; src-Family Kinases; TRPV Cation Channels | 2022 |
Human Stem Cell-Derived TRPV1-Positive Sensory Neurons: A New Tool to Study Mechanisms of Sensitization.
Topics: Capsaicin; Chronic Pain; Humans; Mechanotransduction, Cellular; Sensory Receptor Cells; Stem Cells; TRPV Cation Channels | 2022 |
Decreased Default Mode Network Connectivity Following 24 Hours of Capsaicin-induced Pain Persists During Immediate Pain Relief and Facilitation.
Topics: Brain; Brain Mapping; Capsaicin; Chronic Pain; Cross-Over Studies; Default Mode Network; Female; Humans; Magnetic Resonance Imaging | 2023 |
Effects of Mirogabalin on Hyperalgesia and Chronic Ocular Pain in Tear-Deficient Dry-Eye Rats.
Topics: Animals; Capsaicin; Chronic Pain; Dry Eye Syndromes; Eye Pain; Female; Hyperalgesia; Neuralgia; Rats; Rats, Sprague-Dawley; Tears | 2023 |
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chronic Pain; Formaldehyde; Ganglia, Spinal; Hyperalgesia; Inflammation; Methoxsalen; Mice | 2023 |
Chronic pain models amplify transient receptor potential vanilloid 1 (TRPV1) receptor responses in adult rat spinal dorsal horn.
Topics: Animals; Capsaicin; Chronic Pain; Disease Models, Animal; Excitatory Postsynaptic Potentials; Freund's Adjuvant; Inflammation; Male; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Substantia Gelatinosa; Synaptic Transmission; TRPV Cation Channels | 2019 |
The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain.
Topics: Acetone; Aging; Animals; Behavior; Biogenic Monoamines; Capsaicin; Chronic Pain; Disease Models, Animal; Male; Mice, Inbred C57BL; Peripheral Nerve Injuries; Physical Stimulation; Prefrontal Cortex; Sensory Thresholds | 2020 |
Loss of diffuse noxious inhibitory control after traumatic brain injury in rats: A chronic issue.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Uptake Inhibitors; Animals; Brain Injuries, Traumatic; Capsaicin; Chronic Pain; Diffuse Noxious Inhibitory Control; Duloxetine Hydrochloride; Male; Neural Pathways; Norepinephrine; Pain Measurement; Rats; Rats, Sprague-Dawley; Reboxetine; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2020 |
The impact of pharmaceutical care on the efficacy and safety of transdermal glucosamine sulfate and capsaicin for joint pain.
Topics: Arthralgia; Capsaicin; Chronic Pain; Cross-Sectional Studies; Glucosamine; Humans; Osteoarthritis, Knee; Pharmaceutical Services; Treatment Outcome | 2021 |
8% Capsaicin Patch in Treatment of Peripheral Neuropathic Pain.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Capsaicin; Child; Chronic Pain; Female; Humans; Male; Middle Aged; Neuralgia; Pain Management; Quality of Life; Retrospective Studies; Transdermal Patch; Treatment Outcome; Young Adult | 2020 |
CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache.
Topics: Animals; Antibodies, Monoclonal; Brain Concussion; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Pain; Diffuse Noxious Inhibitory Control; Disease Models, Animal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Post-Traumatic Headache | 2021 |
Postinjury stimulation triggers a transition to nociplastic pain in mice.
Topics: Animals; Capsaicin; Chronic Pain; Female; Humans; Hyperalgesia; Male; Mice; Morphine; Pain Measurement | 2022 |
TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain.
Topics: Animals; Capsaicin; Chemokine CCL2; Chronic Pain; Disease Models, Animal; Female; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Pelvic Pain; Receptors, CCR2; Signal Transduction; Toll-Like Receptor 4; TRPV Cation Channels; Urinary Tract Infections; Uropathogenic Escherichia coli | 2018 |
Pain chronification and chronic pain impair a defensive behavior, but not the ability of acute pain to facilitate it, through the activation of an endogenous analgesia circuit.
Topics: Acute Pain; Animals; Capsaicin; Chronic Pain; Freezing Reaction, Cataleptic; Hydroxy Acids; Hyperalgesia; Male; Neural Pathways; Nociceptive Pain; Nucleus Accumbens; Oleic Acids; Pain Perception; Random Allocation; Rats, Wistar; Receptors, Opioid, mu | 2018 |
Sex differences in measures of central sensitization and pain sensitivity to experimental sleep disruption: implications for sex differences in chronic pain.
Topics: Adult; Antipruritics; Attention; Capsaicin; Central Nervous System Sensitization; Chronic Pain; Female; Hot Temperature; Humans; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Polysomnography; Sex Characteristics; Sleep; Sleep Deprivation | 2019 |
Involvement of Substance P in the Analgesic Effect of Low-Level Laser Therapy in a Mouse Model of Chronic Widespread Muscle Pain.
Topics: Acids; Animals; Capsaicin; Chronic Pain; Cnidarian Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Fibromyalgia; Laser Therapy; Low-Level Light Therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Musculoskeletal Pain; Protein Precursors; Signal Transduction; Substance P; Tachykinins; TRPV Cation Channels | 2019 |
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
Topics: Acetone; Acrolein; Acrylamides; Acute Disease; Alkaloids; Analgesics; Animals; Aporphines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Pain; Cold Temperature; Freund's Adjuvant; Gene Expression; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2013 |
Qutenza patch--our early experience.
Topics: Activities of Daily Living; Analgesics; Capsaicin; Chronic Pain; Humans; Neuralgia; Pain Measurement; Sleep; Surveys and Questionnaires; Transdermal Patch; Treatment Outcome | 2013 |
Cortical theta is increased while thalamocortical coherence is decreased in rat models of acute and chronic pain.
Topics: Acute Pain; Analysis of Variance; Animals; Capsaicin; Cerebral Cortex; Chronic Pain; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Hyperalgesia; Male; Neural Pathways; Rats; Rats, Sprague-Dawley; Thalamus; Theta Rhythm; Time Factors | 2014 |
Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain.
Topics: Animals; Capsaicin; Chronic Pain; Disease Models, Animal; Mice; Mice, Inbred C57BL; Neurons; Nociceptors; Spinal Cord; Trigeminal Ganglion; TRPV Cation Channels | 2014 |
Low-concentration topical capsaicin for chronic neuropathic pain in adults.
Topics: Administration, Topical; Adult; Capsaicin; Chronic Pain; Humans; Neuralgia | 2014 |
Evidence for acute central sensitization to prolonged experimental pain in posttraumatic stress disorder.
Topics: Acute Pain; Adult; Anxiety; Capsaicin; Catastrophization; Central Nervous System Sensitization; Chronic Pain; Comorbidity; Depression; Evidence-Based Medicine; Humans; Hyperalgesia; Male; Pain Threshold; Pressure; Quality of Life; Sensory System Agents; Stress Disorders, Post-Traumatic; Surveys and Questionnaires; Young Adult | 2014 |
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Hyperalgesia; Ischemia; Ketanserin; Male; Mice; Monoterpenes; Neuralgia; Pain, Postoperative; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Acid mediates a prolonged antinociception via substance P signaling in acid-induced chronic widespread pain.
Topics: Acid Sensing Ion Channels; Acids; Animals; Capsaicin; Chronic Pain; Cnidarian Venoms; Disease Models, Animal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Pain Measurement; Signal Transduction; Substance P; TRPV Cation Channels | 2014 |
Pregabalin reduces acute inflammatory and persistent pain associated with nerve injury and cancer in rat models of orofacial pain.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Chronic Pain; Disease Models, Animal; Facial Neoplasms; Facial Pain; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Irritants; Lip Diseases; Male; Neoplasm Transplantation; Orbit; Pain Measurement; Pregabalin; Random Allocation; Rats, Wistar; Sensory System Agents; Trigeminal Neuralgia | 2014 |
Effect of pain chronification and chronic pain on an endogenous pain modulation circuit in rats.
Topics: Analgesics; Animals; Capsaicin; Chronic Pain; Dinoprostone; Hyperalgesia; Male; Nociception; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, mu; Rotarod Performance Test; Somatostatin | 2015 |
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pain; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endocannabinoids; Ethanolamines; Formaldehyde; Male; Medulla Oblongata; Nociceptive Pain; Oleic Acids; Palmitic Acids; Polyunsaturated Alkamides; Rats, Wistar; RNA, Messenger; TRPV Cation Channels | 2016 |
Antinociceptive activity and mechanism of action of hydroalcoholic extract and dichloromethane fraction of Amphilophium crucigerum seeds in mice.
Topics: Analgesics; Animals; Bignoniaceae; Binding, Competitive; Calcium Signaling; Capsaicin; Chronic Pain; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Ethanol; Male; Methylene Chloride; Mice; Neuralgia; Nociception; Nociceptive Pain; Pain Measurement; Phytotherapy; Plant Extracts; Plants, Medicinal; Protein Binding; Seeds; Signal Transduction; Solvents; Spinal Cord; Synaptosomes; TRPV Cation Channels | 2017 |
Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing.
Topics: Action Potentials; Anesthetics, Local; Animals; Axons; Behavior, Animal; Capsaicin; Chronic Pain; Disease Models, Animal; Lidocaine; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sensory Receptor Cells; TRPV Cation Channels | 2013 |