capsaicin and Breast Cancer

capsaicin has been researched along with Breast Cancer in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's1 (3.45)18.2507
2000's6 (20.69)29.6817
2010's16 (55.17)24.3611
2020's5 (17.24)2.80

Authors

AuthorsStudies
Akman, M; Aliyev, E; Erin, N; Korcum, AF; Tanrıöver, G1
Al-Farraj, ES; Arafa, KK; El-Sherbiny, IM; Ghoniem, MG; Radwan, Y1
Jia, H; Li, S; Wu, D; Zhang, Z1
Chen, M; Jiang, W; Lian, B; Liang, Z; Qin, Q; Tan, Q; Wei, C; Xiao, C; Yang, W1
Fu, L; He, M; Liao, X; Wang, F; Wang, Y; Xue, Y; Zhao, L1
Li, BH; Yuan, L1
Blum, W; Buhala, A; Çiğ, B; Jósvay, K; Katona, R; Marton, A; Nazıroğlu, M; Oláh, Z; Pecze, L; Schwaller, B; Vizler, C1
Barbero, R; Cuniberti, B; Odore, R; Re, G; Vercelli, C1
Monteith, GR; Peters, AA; Roberts-Thomson, SJ; Tan, PT; Wu, TT1
Fazzari, J; Lin, H; Murphy, C; Singh, G; Ungard, R1
Barbuto, JA; Bertin, AM; Cury, Y; Damião, MC; de Azevedo, RA; de-Sá-Junior, PL; Ferreira, AK; Ferreira-Junior, WA; Figueiredo, CR; Parise-Filho, R; Pasqualoto, KF; Tavares, MT; Teixeira, SF1
Shim, Y; Song, JM1
Blum, W; Jósvay, K; Oláh, Z; Pecze, L; Petrovics, G; Schwaller, B; Vizler, C1
Ahm Sørensen, J; Bille, C; Larsson, IM1
Chen, DR; Chou, CC; Chou, MJ; Kuo, SJ; Wang, YF; Wu, YC1
Hwang, JT; Lee, YK; Park, OJ; Shin, JI1
Abbassi, S; Iwanski, GB; Karlan, B; Koeffler, HP; La, DT; Leiter, A; Lu, D; Mehta, R; O'Kelly, J; Thoennissen, NH1
Choi, CH; Jung, YK; Oh, SH1
Ahmad, A; Dou, D; Sarkar, FH; Yang, H1
Chang, HC; Chen, DR; Chen, ST; Chien, SY; Kuo, SJ; Tsai, HT1
Ahn, SG; Jung, SH; Lee, BH; Oh, SH; Yoon, JH1
Demir, N; Duymuş, O; Erin, N; Oztürk, S1
Câmara, DA; Damião, MC; de Azevedo, RA; de Souza, DM; de-Sá-Júnior, PL; Ferreira, AK; Parise Filho, R; Pasqualoto, KF; Pereira, A; Tavares, MT1
Bifulco, M; Bisogno, T; De Petrocellis, L; Di Marzo, V; Ligresti, A; Melck, D1
Baba, N; Koseki, M; Murata, Y; Shimoishi, Y; Tada, M; Takahata, K1
Hajtmanova, E; Hanacek, J; Javorkova, N; Kostkova, L; Pecova, R; Tatar, M; Zamecnik, L1
Chueh, PJ; Morré, DJ; Morré, DM1
Bifulco, M; Bisogno, T; De Petrocellis, L; Di Marzo, V; Melck, D; Orlando, P; Vogel, Z; Zagoory, O1
Evans, RJ; Watson, CP; Watt, VR1

Reviews

2 review(s) available for capsaicin and Breast Cancer

ArticleYear
Extraction, purification, bioactivity and pharmacological effects of capsaicin: a review.
    Critical reviews in food science and nutrition, 2022, Volume: 62, Issue:19

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Capsaicin; Capsicum; Female; Humans

2022
The Post-mastectomy Pain Syndrome-A Systematic Review of the Treatment Modalities.
    The breast journal, 2017, Volume: 23, Issue:3

    Topics: Adipose Tissue; Administration, Topical; Antidepressive Agents; Breast Neoplasms; Capsaicin; Female; Humans; Mastectomy; Pain, Postoperative; Transplantation, Autologous

2017

Trials

1 trial(s) available for capsaicin and Breast Cancer

ArticleYear
Changes of cough reflex sensitivity induced by cancer radiotherapy of chest and neck regions.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 4

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Capsaicin; Cough; Female; Gamma Rays; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neck; Radiotherapy; Reflex; Thorax

2006

Other Studies

26 other study(ies) available for capsaicin and Breast Cancer

ArticleYear
Olvanil activates sensory nerve fibers, increases T cell response and decreases metastasis of breast carcinoma.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Animals; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Proliferation; Female; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Nerve Fibers; Pain; Sensory Receptor Cells; TRPV Cation Channels

2022
An
    Drug development and industrial pharmacy, 2023, Volume: 49, Issue:3

    Topics: Breast Neoplasms; Capsaicin; Female; Fluorouracil; Humans; Lipids; Nanocapsules

2023
Capsaicin suppresses breast cancer cell viability by regulating the CDK8/PI3K/Akt/Wnt/β‑catenin signaling pathway.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Apoptosis; beta Catenin; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; China; Cyclin-Dependent Kinase 8; Female; Gene Expression Regulation, Neoplastic; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Wnt Signaling Pathway

2020
Capsaicin Inhibits Proliferation and Induces Apoptosis in Breast Cancer by Down-Regulating FBI-1-Mediated NF-κB Pathway.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Capsaicin; Cell Proliferation; DNA-Binding Proteins; Down-Regulation; Drug Screening Assays, Antitumor; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Proto-Oncogene Mas; Transcription Factors; Tumor Cells, Cultured

2021
[Inhibitory effects of capsaicin on migration and invasion of breast cancer MDA-MB-231 cells and its mechanism].
    Sheng li xue bao : [Acta physiologica Sinica], 2017, Apr-25, Volume: 69, Issue:2

    Topics: Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Down-Regulation; Focal Adhesion Kinase 1; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Paxillin; Phosphorylation; src-Family Kinases

2017
Targeting breast cancer cells by MRS1477, a positive allosteric modulator of TRPV1 channels.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Allosteric Regulation; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Calcium Signaling; Capsaicin; Cell Survival; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Molecular Targeted Therapy; Oxidative Stress; Reactive Oxygen Species; TRPV Cation Channels; Tumor Microenvironment; Xenograft Model Antitumor Assays

2017
Expression and functionality of TRPV1 receptor in human MCF-7 and canine CF.41 cells.
    Veterinary and comparative oncology, 2015, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Proliferation; Diterpenes; Dogs; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; MCF-7 Cells; TRPV Cation Channels

2015
Consequences of activating the calcium-permeable ion channel TRPV1 in breast cancer cells with regulated TRPV1 expression.
    Cell calcium, 2014, Volume: 56, Issue:2

    Topics: Breast Neoplasms; Calcium; Capsaicin; Cell Proliferation; Cell Survival; Doxorubicin; Female; Humans; MCF-7 Cells; Proto-Oncogene Proteins c-fos; Receptor-Interacting Protein Serine-Threonine Kinases; TRPV Cation Channels; Up-Regulation

2014
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain.
    Scientific reports, 2015, Feb-11, Volume: 5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Bone and Bones; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Dopamine Agonists; Drug Discovery; Female; Glutamic Acid; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Pain; Signal Transduction; Small Molecule Libraries

2015
RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:9

    Topics: Animals; Apoptosis; Breast Neoplasms; Capsaicin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Molecular; Neoplasm Proteins; Protein Binding; Xenograft Model Antitumor Assays

2015
Quantum dot nanoprobe-based high-content monitoring of notch pathway inhibition of breast cancer stem cell by capsaicin.
    Molecular and cellular probes, 2015, Volume: 29, Issue:6

    Topics: Apoptosis; Breast Neoplasms; Capsaicin; Cell Nucleus; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; MCF-7 Cells; Nanoparticles; Neoplastic Stem Cells; Quantum Dots; Receptors, Notch; Signal Transduction; Single-Cell Analysis

2015
Activation of endogenous TRPV1 fails to induce overstimulation-based cytotoxicity in breast and prostate cancer cells but not in pain-sensing neurons.
    Biochimica et biophysica acta, 2016, Volume: 1863, Issue:8

    Topics: Animals; Apoptosis; Breast; Breast Neoplasms; Capsaicin; Cells, Cultured; Diterpenes; Epithelial Cells; Female; Humans; Male; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Recombinant Proteins; Sensory Receptor Cells; Trigeminal Ganglion; TRPV Cation Channels

2016
Capsaicin-induced apoptosis in human breast cancer MCF-7 cells through caspase-independent pathway.
    Oncology reports, 2009, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Breast Neoplasms; Calcium; Capsaicin; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Microscopy, Confocal; Reactive Oxygen Species

2009
Anti-inflammatory and anticarcinogenic effect of genistein alone or in combination with capsaicin in TPA-treated rat mammary glands or mammary cancer cell line.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Blotting, Western; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Drug Synergism; Female; Genistein; Humans; Mammary Glands, Animal; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

2009
Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway.
    Oncogene, 2010, Jan-14, Volume: 29, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Capsaicin; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Models, Biological; Receptor, ErbB-2; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Xenograft Model Antitumor Assays

2010
Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis.
    Molecular pharmacology, 2010, Volume: 78, Issue:1

    Topics: Apoptosis; Autophagy; Base Sequence; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Endoplasmic Reticulum; Enzyme Activation; Female; Humans; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; RNA, Small Interfering

2010
Tumor cell growth inhibition is correlated with levels of capsaicin present in hot peppers.
    Nutrition and cancer, 2011, Volume: 63, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Capsaicin; Capsicum; Cell Line, Tumor; Cell Proliferation; Female; Growth Inhibitors; Humans; Phytotherapy; Plant Extracts

2011
Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction.
    Human & experimental toxicology, 2011, Volume: 30, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Breast Neoplasms; Capsaicin; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Female; Humans; Membrane Potential, Mitochondrial; Mitochondria; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; S Phase

2011
Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
    Biochemical pharmacology, 2012, Mar-15, Volume: 83, Issue:6

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Autophagy; Breast Neoplasms; Caffeine; Capsaicin; Cell Cycle Proteins; Cell Line, Tumor; Chromones; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Activation; Female; Humans; Morpholines; Nuclear Proteins; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Pyrones; S Phase Cell Cycle Checkpoints; Signal Transduction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2012
Activation of vagus nerve by semapimod alters substance P levels and decreases breast cancer metastasis.
    Regulatory peptides, 2012, Nov-10, Volume: 179, Issue:1-3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Female; Hydrazones; Liver Neoplasms, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neprilysin; Sensory Receptor Cells; Substance P; Vagotomy; Vagus Nerve

2012
RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells.
    Toxicology and applied pharmacology, 2013, Feb-01, Volume: 266, Issue:3

    Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Capsaicin; Cell Survival; DNA Fragmentation; Female; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Magnetic Resonance Spectroscopy; Mass Spectrometry; MCF-7 Cells; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microtubules; Models, Molecular

2013
Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Amides; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Breast Neoplasms; Cannabinoids; Capsaicin; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Ethanolamines; Female; Humans; Palmitic Acids; Receptors, Cannabinoid; Receptors, Drug; Signal Transduction; Tumor Cells, Cultured

2002
Apoptosis induction by dohevanil, a DHA substitutive analog of capsaicin, in MCF-7 cells.
    Life sciences, 2006, Feb-23, Volume: 78, Issue:13

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Breast Neoplasms; Capsaicin; Caspase 3; Caspases; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Female; Humans

2006
Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-14, Volume: 92, Issue:6

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Capsaicin; Cell Division; Cell Line; Cell Line, Transformed; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium; Female; HeLa Cells; Humans; Kidney; Kinetics; Leukemia, Promyelocytic, Acute; Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Ovarian Neoplasms; Rats; Tumor Cells, Cultured

1995
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.
    The Biochemical journal, 2001, Aug-15, Volume: 358, Issue:Pt 1

    Topics: Amides; Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acids; Blotting, Western; Breast Neoplasms; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Cell Division; Colforsin; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Glycerides; Humans; Hydrolysis; Inhibitory Concentration 50; Palmitic Acids; Polyunsaturated Alkamides; Protein Binding; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured

2001
The post-mastectomy pain syndrome and the effect of topical capsaicin.
    Pain, 1989, Volume: 38, Issue:2

    Topics: Administration, Topical; Adult; Aged; Breast Neoplasms; Capsaicin; Female; Follow-Up Studies; Humans; Intercostal Nerves; Mastectomy; Middle Aged; Pain; Thoracic Nerves; Time Factors

1989