capsaicin and Adjuvant Arthritis

capsaicin has been researched along with Adjuvant Arthritis in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19906 (17.65)18.7374
1990's10 (29.41)18.2507
2000's8 (23.53)29.6817
2010's7 (20.59)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Chen, Q; Gong, D; Li, P; Liu, P; Wang, F; Wang, J; Wen, W; Xu, S1
da Silva, JT; Ro, JY; Tricou, C; Yang, D; Zhang, R; Zhang, Y1
Bölcskei, K; Botz, B; Helyes, Z; Horváth, ÁI; Kriszta, G; Mócsai, A1
Borbély, É; Botz, B; Helyes, Z; Kiss, T; Pintér, E; Szabadfi, K; Szolcsányi, J1
Mazumder, B; Rudrapal, M; Sarwa, KK; Verma, VK1
Bölcskei, K; Borbély, É; Botz, B; Csepregi, JZ; Helyes, Z; Kenyér, T; Kereskai, L; Kiss, T; Mócsai, A; Pintér, E; Szolcsányi, J1
Kaur, CD; Mazumder, B; Sarwa, KK; Suresh, PK1
Aono, H; Murai, M; Nose, M; Oki, K; Sasano, M; Seki, I; Setoguchi, C; Suhara, H; Tsuji, F1
de Mello, CF; de Oliveira Ferreira, AP; Ferreira, J; Rossato, MF; Velloso, NA1
Al-Khrasani, M; Brendl, U; Fürst, S; Mousa, SA; Schäfer, M; Shaqura, M1
Amagase, K; Satoh, H; Takeuchi, K1
McDougall, JJ; Zhang, C1
Constandil, L; Espinosa, J; Hernández, A; Infante, C; Lapeyra, CD; Pelissier, T1
Cui, ZJ; Hu, F; Sun, WW; Yang, WX; Zhao, XT1
Colpaert, FC; Donnerer, J; Lembeck, F1
Bervoets, K; Colpaert, FC1
Hara, A; Kisara, K; Matsumura, H; Sakurada, S; Sakurada, T1
Donaldson, LF; McQueen, DS; Seckl, JR1
Ahmed, M; Bjurholm, A; Kreicbergs, A; Lundeberg, T; Schultzberg, M; Srinivasan, GR; Theodorsson, E1
Ahmed, M; Bjurholm, A; Kreicbergs, A; Schultzberg, M; Theodorsson, E1
Cambridge, H1
Davis, A; Perkins, MN1
Gur Aryeh, I; Niv, D1
Joe, B; Lokesh, BR; Rao, UJ1
Cruwys, SC; Garrett, NE; Kidd, BL; Tomlinson, DR1
Homonko, DA; Marshall, KW; Theriault, E1
Bellinger, DL; Engan, C; Felten, DL; Lorton, D; Lubahn, C; Schaller, J1
Chessell, IP; Gauldie, SD; McQueen, DS; Pertwee, R1
Cruwys, SC; Hood, VC; Kidd, BL; Urban, L1
Kasai, M; Mizumura, K1
Bohne, RL; Brand, LM; Fanelli, R; Lade, DA; Loomans, ME; Maddin, CS; Moorehead, DP; Reller, HH; Schwen, RJ; Skare, KL1
Kuraishi, Y; Nanayama, T; Ohno, H; Satoh, M1
Chiu, B; Inman, RD; Marshall, W; Rabinovich, S1
Basbaum, AI; Dardick, SJ; Helms, C; Levine, JD; Roizen, MF1

Reviews

1 review(s) available for capsaicin and Adjuvant Arthritis

ArticleYear
[Capsaicin for arthritic pain].
    Harefuah, 1996, Mar-15, Volume: 130, Issue:6

    Topics: Analgesics; Animals; Arthritis; Arthritis, Experimental; Capsaicin; Humans; Pain; Substance P

1996

Trials

1 trial(s) available for capsaicin and Adjuvant Arthritis

ArticleYear
Topical Analgesic Nanolipid Vesicles Formulation of Capsaicinoids Extract of Bhut Jolokia (Capsicum chinense Jacq): Pharmacodynamic Evaluation in Rat Models and Acceptability studies in Human Volunteers.
    Current drug delivery, 2016, Volume: 13, Issue:8

    Topics: Administration, Topical; Analgesics; Animals; Arthritis, Experimental; Capsaicin; Capsicum; Carrageenan; Drug Carriers; Formaldehyde; Freund's Adjuvant; Healthy Volunteers; Humans; In Vitro Techniques; Inflammation; Male; Nanoparticles; Phosphatidylcholines; Phytotherapy; Plant Extracts; Rats, Wistar; Skin; Skin Absorption

2016

Other Studies

32 other study(ies) available for capsaicin and Adjuvant Arthritis

ArticleYear
SZAP exerts analgesic effects on rheumatalgia in CIA rats by suppressing pain hyperalgesia and inhibiting TRPV1 and P2X3.
    Journal of ethnopharmacology, 2022, Feb-10, Volume: 284

    Topics: Administration, Topical; Animals; Arthritis, Experimental; Capsaicin; Collagen; Diclofenac; Drugs, Chinese Herbal; Gene Expression Regulation; Male; Phytotherapy; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; TRPV Cation Channels

2022
Age and Sex Differences in Acute and Osteoarthritis-Like Pain Responses in Rats.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 07-13, Volume: 75, Issue:8

    Topics: Aging; Animals; Arthritis, Experimental; Behavior, Animal; Capsaicin; Enzyme Inhibitors; Female; Hyperalgesia; Iodoacetic Acid; Male; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats, Inbred F344; Sex Factors; Spinal Cord; Weight-Bearing

2020
Capsaicin-Sensitive Peptidergic Sensory Nerves Are Anti-Inflammatory Gatekeepers in the Hyperacute Phase of a Mouse Rheumatoid Arthritis Model.
    International journal of molecular sciences, 2021, Feb-08, Volume: 22, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Capsaicin; Diterpenes; Male; Mice; Mice, Inbred BALB C; Neurogenic Inflammation; Neuropeptides; Reactive Oxygen Species; Sensory System Agents

2021
Complex Role of Capsaicin-Sensitive Afferents in the Collagen Antibody-Induced Autoimmune Arthritis of the Mouse.
    Scientific reports, 2018, 10-29, Volume: 8, Issue:1

    Topics: Animals; Ankle Joint; Antibodies; Arthritis, Experimental; Body Weight; Capsaicin; Disease Models, Animal; Diterpenes; Edema; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Severity of Illness Index; X-Ray Microtomography

2018
Potential of capsaicin-loaded transfersomes in arthritic rats.
    Drug delivery, 2015, Volume: 22, Issue:5

    Topics: Administration, Cutaneous; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Capsaicin; Chemistry, Pharmaceutical; Joints; Liposomes; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Phosphatidylcholines; Rats; Sensory System Agents; Skin Absorption

2015
Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis.
    Brain, behavior, and immunity, 2015, Volume: 45

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Capsaicin; Disease Models, Animal; Diterpenes; Edema; Hindlimb; Hyperalgesia; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nociceptors; Pain Threshold; Peroxidase; Reactive Oxygen Species; Sensory System Agents; Somatostatin; Tarsus, Animal; TRPV Cation Channels; X-Ray Microtomography

2015
SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-alpha production through the activation of capsaicin-sensitive afferent neurons mediated via transient receptor potential vanilloid 1 in vivo.
    European journal of pharmacology, 2008, Jul-07, Volume: 588, Issue:2-3

    Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Pyridines; Rats; Rats, Inbred Lew; Somatostatin; TRPV Cation Channels; Tumor Necrosis Factor-alpha; Urea

2008
Spinal levels of nonprotein thiols are related to nociception in mice.
    The journal of pain, 2010, Volume: 11, Issue:6

    Topics: Acetylcysteine; Acute Disease; Analgesics; Animals; Antimetabolites; Arthritis, Experimental; Behavior, Animal; Buthionine Sulfoximine; Capsaicin; Disease Models, Animal; Female; Foot Injuries; Lipid Peroxidation; Lumbar Vertebrae; Male; Mice; Oxidative Stress; Pain; Spinal Cord; Sulfhydryl Compounds

2010
Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid-containing immune cells to inhibit inflammatory pain.
    Brain, behavior, and immunity, 2010, Volume: 24, Issue:8

    Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Endorphins; Endothelium, Vascular; Flow Cytometry; Freund's Adjuvant; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Male; Nerve Fibers; Oxidopamine; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Sensory Receptor Cells; Sympathetic Nervous System; Sympatholytics; Tyrosine 3-Monooxygenase

2010
Exacerbation of nonsteroidal anti-inflammatory drug-induced small intestinal lesions by antisecretory drugs in rats: the role of intestinal motility.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capsaicin; Dose-Response Relationship, Drug; Gastrointestinal Motility; Histamine H2 Antagonists; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Proton Pump Inhibitors; Rats; Rats, Wistar; Sensory Receptor Cells; Stomach Ulcer

2012
Stimulation of sensory neuropeptide release by nociceptin/orphanin FQ leads to hyperaemia in acutely inflamed rat knees.
    British journal of pharmacology, 2006, Volume: 148, Issue:7

    Topics: Animals; Arthritis, Experimental; Capsaicin; Dose-Response Relationship, Drug; Hyperemia; Image Processing, Computer-Assisted; Joints; Kaolin; Leukocytes; Male; Mast Cells; Neuropeptides; Nociceptin; Opioid Peptides; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical; Substance P; Synovial Fluid; Vasodilation

2006
Antinociceptive effect and interaction of uncompetitive and competitive NMDA receptor antagonists upon capsaicin and paw pressure testing in normal and monoarthritic rats.
    Pain, 2008, Volume: 134, Issue:1-2

    Topics: Analgesics; Animals; Arthritis, Experimental; Binding, Competitive; Capsaicin; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Injections, Spinal; Pain; Pain Measurement; Physical Stimulation; Pressure; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vocalization, Animal

2008
TRPV1 mediates cell death in rat synovial fibroblasts through calcium entry-dependent ROS production and mitochondrial depolarization.
    Biochemical and biophysical research communications, 2008, May-16, Volume: 369, Issue:4

    Topics: Animals; Apoptosis; Arthritis, Experimental; Calcium; Capsaicin; Cytosol; Fibroblasts; Hyperplasia; Male; Membrane Potential, Mitochondrial; NADPH Oxidases; Onium Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Synovial Membrane; TRPV Cation Channels

2008
Effects of capsaicin on inflammation and on the substance P content of nervous tissues in rats with adjuvant arthritis.
    Life sciences, 1983, Apr-18, Volume: 32, Issue:16

    Topics: Animals; Arthritis; Arthritis, Experimental; Capsaicin; Fatty Acids, Unsaturated; Inflammation; Kinetics; Male; Mycobacterium; Nervous System; Rats; Rats, Inbred Strains; Substance P

1983
Respiratory effects of intrathecal capsaicin in arthritic and non-arthritic rats.
    Life sciences, 1984, Jun-18, Volume: 34, Issue:25

    Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Capsaicin; Injections, Spinal; Male; Pain; Rats; Rats, Inbred Strains; Respiration; Substance P

1984
Antinociceptive effects of neonatal capsaicin in rats with adjuvant arthritis.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:3

    Topics: Analgesics; Animals; Animals, Newborn; Arthritis; Arthritis, Experimental; Body Weight; Capsaicin; Hot Temperature; Male; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds

1984
Neuropeptide gene expression and capsaicin-sensitive primary afferents: maintenance and spread of adjuvant arthritis in the rat.
    The Journal of physiology, 1995, Jul-15, Volume: 486 ( Pt 2)

    Topics: Animals; Arthritis, Experimental; Capsaicin; Disease Progression; Ganglia, Spinal; Gene Expression; Male; Neurons, Afferent; Neuropeptides; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve

1995
Capsaicin effects on substance P and CGRP in rat adjuvant arthritis.
    Regulatory peptides, 1995, Jan-05, Volume: 55, Issue:1

    Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglia, Spinal; Immunohistochemistry; Organ Size; Rats; Rats, Inbred Lew; Substance P; Synovial Membrane; Tarsus, Animal; Up-Regulation

1995
Neuropeptide Y- and vasoactive intestinal polypeptide-like immunoreactivity in adjuvant arthritis: effects of capsaicin treatment.
    Neuropeptides, 1995, Volume: 29, Issue:1

    Topics: Animals; Arthritis, Experimental; Autonomic Nervous System; Capsaicin; Female; Immunohistochemistry; Neuropeptide Y; Radioimmunoassay; Rats; Rats, Inbred Lew; Sensory Receptor Cells; Vasoactive Intestinal Peptide

1995
The 21st Meeting of the British Inflammation Research Society, "Inflammatory pain", King's College, London, 19th December, 1994.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:6

    Topics: Arthritis, Experimental; Asthma; Bronchial Hyperreactivity; Capsaicin; Humans; Inflammation; Nerve Growth Factors; Neurons, Afferent; Nitric Oxide Synthase; Pain; Receptors, Bradykinin; Spinal Cord; Up-Regulation

1995
The effect of capsaicin and conventional analgesics in two models of monoarthritis in the rat.
    Agents and actions, 1993, Volume: 38 Spec No

    Topics: Animals; Arthritis, Experimental; Capsaicin; Disease Models, Animal; Enflurane; Female; Freund's Adjuvant; Hyperalgesia; Rats; Rats, Sprague-Dawley; Uric Acid

1993
Presence of an acidic glycoprotein in the serum of arthritic rats: modulation by capsaicin and curcumin.
    Molecular and cellular biochemistry, 1997, Volume: 169, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biomarkers; Capsaicin; Curcumin; Eugenol; Glycoproteins; Male; Molecular Weight; Rats; Rats, Wistar; Spices

1997
Effect of capsaicin on substance P and nerve growth factor in adjuvant arthritic rats.
    Neuroscience letters, 1997, Jul-11, Volume: 230, Issue:1

    Topics: Animals; Arthritis, Experimental; Capsaicin; Ganglia, Spinal; Male; Nerve Growth Factors; Protein Precursors; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Reference Values; RNA, Messenger; Sciatic Nerve; Skin; Substance P; Tachykinins; Transcription, Genetic

1997
A single capsaicin injection partially depletes neuropeptides but does not ameliorate inflammation severity in established feline antigen induced arthritis.
    The Journal of rheumatology, 1997, Volume: 24, Issue:9

    Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Immunohistochemistry; Injections, Intra-Articular; Knee Joint; Substance P; Synovial Membrane; Synovitis

1997
Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis.
    Neuroimmunomodulation, 2000, Volume: 7, Issue:3

    Topics: Afferent Pathways; Animals; Arthritis, Experimental; Capsaicin; Denervation; Freund's Adjuvant; Hindlimb; Injections, Intralymphatic; Lymph Nodes; Male; Nerve Fibers; Rats; Rats, Inbred Lew; Substance P

2000
Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints.
    British journal of pharmacology, 2001, Volume: 132, Issue:3

    Topics: Animals; Arachidonic Acids; Arthritis, Experimental; Calcium Channel Blockers; Capsaicin; Disease Models, Animal; Drug Interactions; Endocannabinoids; Knee Joint; Male; Nociceptors; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Drug; Treatment Outcome; TRPV Cation Channels

2001
The neurogenic contribution to synovial leucocyte infiltration and other outcome measures in a guinea pig model of arthritis.
    Neuroscience letters, 2001, Feb-23, Volume: 299, Issue:3

    Topics: Animals; Arthritis, Experimental; Capsaicin; Cell Movement; Disease Models, Animal; Guinea Pigs; Joints; Leukocytes; Macrophages; Male; Neurogenic Inflammation; Neurons, Afferent; Neuropeptides; Peripheral Nerves; Synovitis; T-Lymphocytes; Treatment Outcome

2001
Effects of PGE(2) on neurons from rat dorsal root ganglia in intact and adjuvant-inflamed rats: role of NGF on PGE(2)-induced depolarization.
    Neuroscience research, 2001, Volume: 41, Issue:4

    Topics: Action Potentials; Animals; Arthritis, Experimental; Bradykinin; Capsaicin; Cells, Cultured; Dinoprostone; Freund's Adjuvant; Ganglia, Spinal; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Rats; Rats, Wistar; Sensory Thresholds; Tachyphylaxis

2001
Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345.
    Agents and actions, 1990, Volume: 31, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Capsaicin; Carrageenan; Cell Movement; Edema; Guinea Pigs; Inflammation; Leukocytes; Male; Mice; Otitis; Platelet Aggregation Inhibitors; Pleurisy; Rats; Rats, Inbred Strains; Vanillic Acid

1990
Capsaicin-induced release of calcitonin gene-related peptide from dorsal horn slices is enhanced in adjuvant arthritic rats.
    Neuroscience research, 1989, Volume: 6, Issue:6

    Topics: Animals; Arthritis; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Spinal Cord

1989
Neuromodulation of synovitis: capsaicin effect on severity of experimental arthritis.
    Journal of neuroimmunology, 1989, Volume: 24, Issue:1-2

    Topics: Animals; Antibodies; Arthritis; Arthritis, Experimental; Capsaicin; Cats; Peripheral Nerves; Serum Albumin, Bovine; Synovitis

1989
Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:12

    Topics: Animals; Arthritis; Arthritis, Experimental; Capsaicin; Ganglia, Spinal; Hypertension; Male; Morphine; Neurons, Afferent; Neurons, Efferent; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Sympathectomy; Sympathetic Nervous System

1986