Page last updated: 2024-08-24

capecitabine and Disease Models, Animal

capecitabine has been researched along with Disease Models, Animal in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.09)18.2507
2000's8 (36.36)29.6817
2010's7 (31.82)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Riwanto, I; Tendean, M1
Alwaseem, H; Bahr, A; de Stanchina, E; Fanchon, L; Humm, JL; Molina, H; O'Donoghue, I; Pillarsetty, N; Russell, J1
Fanchon, LM; Gangangari, K; Humm, JL; O'Donoghue, I; Pillarsetty, N; Russell, J; Yu, KH1
Hiromoto, S; Inoue, M; Kawashiri, T; Kobayashi, D; Mine, K; Shimazoe, T; Uchida, M; Yamanaka, N1
Bapiro, TE; Bramhall, JL; Cook, N; Courtin, A; Jodrell, DI; Krippendorff, BF; Neesse, A; Richards, FM; Tuveson, DA1
Ahn, KS; Chen, L; Kumar, AP; Li, F; Manu, KA; Sethi, G; Shanmugam, MK; Siveen, KS1
Barquinero, J; Casacuberta-Serra, S; Ferrer, G; Hirano, M; López-Estévez, S; Mansilla, MJ; Martí, R; Martorell, L; Torres-Torronteras, J1
Chen, J; Chen, M; He, Q; Li, G; Luo, P; Peng, X; Shao, J; Xu, Z; Yang, B; Zhu, H; Zhu, Y1
Evans, DB; Hayashi, S; Kataoka, M; Kondoh, K; Mori, K; Moriya, Y; Sawada, N; Yamaguchi, Y; Yasuno, H1
Fong, CW; Kumar, AP; Li, F; Manu, KA; Ramachandran, L; Sethi, G; Shanmugam, MK; Tan, P1
Aggarwal, BB; Baladandayuthapani, V; Deorukhkar, A; Diagaradjane, P; Guha, S; Kannappan, R; Krishnan, S; Prasad, S; Reuter, S; Sung, B; Wei, C; Yadav, VR1
Kurokawa, S; Matsuzaki, A; Morita, T; Tokue, A1
Holland, M; Reichardt, P; Sternberg, CN1
Demertzidis, CI; Economou, LD; Konstantinidis, HD; Mpallas, KD; Pissanidou, TT; Sioga, AC1
Twelves, CJ1
Burris, HA1
Endo, M; Fukase, Y; Ishikawa, T; Ishitsuka, H; Sawada, N; Shinbori, N; Tanaka, Y1
Horii, I; Ishitsuka, H; Shimma, N1
Matsuzaki, A; Morita, T; Tokue, A1
Fujimoto-Ouchi, K; Tanaka, Y; Tominaga, T1
Lawrence, TS; McGinn, CJ1

Reviews

4 review(s) available for capecitabine and Disease Models, Animal

ArticleYear
Development of and clinical experience with capecitabine (Xeloda) in the treatment of solid tumours.
    European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2004, Volume: 8 Suppl 1

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Diarrhea; Disease Models, Animal; Drug Evaluation, Preclinical; Fluorouracil; Gastrointestinal Neoplasms; Home Care Services; Humans; Nurse's Role; Oncology Nursing; Safety; Stomatitis; Survival Rate; Treatment Outcome

2004
Preclinical investigations with epothilones in breast cancer models.
    Seminars in oncology, 2008, Volume: 35, Issue:2 Suppl 2

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Capecitabine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Epothilones; Female; Fluorouracil; Humans; Mice; Mice, Nude; Microtubules; Paclitaxel; Tubulin Modulators

2008
[Discovery and development of novel anticancer drug capecitabine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1999, Volume: 119, Issue:12

    Topics: Animals; Antineoplastic Agents; Biological Availability; Bridged-Ring Compounds; Capecitabine; Cyclophosphamide; Deoxycytidine; Disease Models, Animal; Drug Administration Schedule; Drug Design; Fluorouracil; Humans; Liver; Mice; Neoplasms; Taxoids; Thymidine Phosphorylase; Up-Regulation

1999
Recent advances in the use of radiosensitizing nucleosides.
    Seminars in radiation oncology, 2001, Volume: 11, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Disease Models, Animal; Fluorouracil; Gemcitabine; Humans; Neoplasms; Radiation-Sensitizing Agents

2001

Other Studies

18 other study(ies) available for capecitabine and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
The Effects of Phyllanthus niruri Linn on Infiltrating Dendritic Cell and Ratio of Neutrophile/Lymphocytes in Chemotherapy of Sprague-Dawley Rats with Colorectal Cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2021, Nov-01, Volume: 22, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Dendritic Cells; Disease Models, Animal; Leukocyte Count; Lymphocytes; Male; Neutrophils; Phyllanthus; Rats; Rats, Sprague-Dawley

2021
Analysis of capecitabine metabolites in conjunction with digital autoradiography in a murine model of pancreatic cancer suggests extensive drug penetration through the tumor.
    Pharmacology research & perspectives, 2022, Volume: 10, Issue:2

    Topics: Animals; Autoradiography; Capecitabine; Disease Models, Animal; Humans; Mice; Pancreatic Neoplasms; Prodrugs

2022
Comparing the intra-tumoral distribution of Gemcitabine, 5-Fluorouracil, and Capecitabine in a murine model of pancreatic ductal adenocarcinoma.
    PloS one, 2020, Volume: 15, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Pancreatic Ductal; Cell Hypoxia; Deoxycytidine; Diagnostic Techniques, Radioisotope; Disease Models, Animal; Fluorouracil; Gemcitabine; Mice; Mice, Inbred C57BL; Organoids; Pancreatic Neoplasms

2020
Use of omeprazole, the proton pump inhibitor, as a potential therapy for the capecitabine-induced hand-foot syndrome.
    Scientific reports, 2021, 04-26, Volume: 11, Issue:1

    Topics: Animals; Capecitabine; Disease Models, Animal; Hand-Foot Syndrome; Mice; Mice, Inbred ICR; Omeprazole; Proton Pump Inhibitors

2021
Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytidine Deaminase; Deoxycytidine; Disease Models, Animal; Drug Screening Assays, Antitumor; Fluorouracil; Gemcitabine; Mice; Mice, Transgenic; Neoplasm Transplantation; Pancreatic Neoplasms; Prodrugs; Tissue Distribution

2013
Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.
    Journal of molecular medicine (Berlin, Germany), 2014, Volume: 92, Issue:3

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Capecitabine; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Disease Models, Animal; DNA; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mice; Mice, Nude; Neovascularization, Pathologic; NF-kappa B; Protein Binding; Simvastatin; Stomach Neoplasms; Xenograft Model Antitumor Assays

2014
Thymidine phosphorylase is both a therapeutic and a suicide gene in a murine model of mitochondrial neurogastrointestinal encephalomyopathy.
    Gene therapy, 2014, Volume: 21, Issue:7

    Topics: Animals; Capecitabine; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine; Disease Models, Animal; Fluorouracil; Gene Knockout Techniques; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Intestinal Pseudo-Obstruction; Lentivirus; Male; Mice; Mice, Inbred C57BL; Mitochondrial Encephalomyopathies; Muscular Dystrophy, Oculopharyngeal; Ophthalmoplegia; Thymidine Phosphorylase

2014
The contribution of keratinocytes in capecitabine-stimulated hand-foot-syndrome.
    Environmental toxicology and pharmacology, 2017, Volume: 49

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Capecitabine; Cell Line; Cell Proliferation; Disease Models, Animal; Hand-Foot Syndrome; Humans; Keratinocytes; Male; Membrane Potential, Mitochondrial; Mice, Inbred ICR

2017
Antitumor activity of chemoendocrine therapy in premenopausal and postmenopausal models with human breast cancer xenografts.
    Oncology reports, 2012, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Breast Neoplasms; Capecitabine; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Female; Fluorouracil; Genes, Reporter; Humans; Letrozole; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Postmenopause; Premenopause; Tamoxifen; Thymidine Phosphorylase; Triazoles; Xenograft Model Antitumor Assays

2012
First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Apr-15, Volume: 18, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Capecitabine; Cell Line, Tumor; Cell Proliferation; Chromans; Cyclin D1; Cyclooxygenase 2; Deoxycytidine; Disease Models, Animal; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Intercellular Adhesion Molecule-1; Ki-67 Antigen; Matrix Metalloproteinase 9; Mice; Mice, Nude; Mitochondria; Neovascularization, Pathologic; NF-kappa B; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-bcl-2; Receptors, CXCR4; Repressor Proteins; Stomach Neoplasms; Survivin; Vascular Endothelial Growth Factor A; Vitamin E; Xenograft Model Antitumor Assays

2012
Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Sep-15, Volume: 18, Issue:18

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; beta Catenin; Capecitabine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Fluorouracil; Humans; Ki-67 Antigen; Male; Mice; Mice, Nude; Neoplasm Metastasis; NF-kappa B; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Tumor Suppressor Proteins; Ursolic Acid; Xenograft Model Antitumor Assays

2012
Forced expression of cytidine deaminase confers sensitivity to capecitabine.
    Oncology, 2003, Volume: 65, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Cell Survival; Cytidine Deaminase; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Disease Models, Animal; DNA, Complementary; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Fluorouracil; Gemcitabine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Thymidine Phosphorylase; Thymidylate Synthase; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2003
Histological evaluation of colonic anastomotic healing, during perioperative Capecitabine administration. Experimental study in rats.
    Histology and histopathology, 2007, Volume: 22, Issue:11

    Topics: Anastomosis, Surgical; Animals; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Colon; Deoxycytidine; Disease Models, Animal; Fluorouracil; Necrosis; Preoperative Care; Rats; Rats, Wistar; Wound Healing

2007
Defining the optimal schedule of drug administration: art or science?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Apr-10, Volume: 26, Issue:11

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Disease Models, Animal; Drug Administration Schedule; Fluorouracil; Humans; Models, Biological; Research Design

2008
Induction of thymidine phosphorylase expression and enhancement of efficacy of capecitabine or 5'-deoxy-5-fluorouridine by cyclophosphamide in mammary tumor models.
    International journal of cancer, 1999, Sep-24, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Capecitabine; Cyclophosphamide; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Floxuridine; Fluorouracil; Humans; Kinetics; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Thymidine Phosphorylase; Time Factors; Up-Regulation

1999
Enhancement of sensitivity to capecitabine in human renal carcinoma cells transfected with thymidine phosphorylase cDNA.
    International journal of cancer, 2001, May-01, Volume: 92, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Renal Cell; Cell Survival; Deoxycytidine; Disease Models, Animal; DNA, Complementary; Drug Screening Assays, Antitumor; Floxuridine; Fluorouracil; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Thymidine Phosphorylase; Transfection; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001
Schedule dependency of antitumor activity in combination therapy with capecitabine/5'-deoxy-5-fluorouridine and docetaxel in breast cancer models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease Models, Animal; Docetaxel; Drug Administration Schedule; Drug Combinations; Female; Floxuridine; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Paclitaxel; Taxoids; Thymidine Phosphorylase; Tumor Cells, Cultured; Up-Regulation; Xenograft Model Antitumor Assays

2001