capecitabine has been researched along with Cancer of Rectum in 565 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 118 (20.88) | 29.6817 |
2010's | 361 (63.89) | 24.3611 |
2020's | 86 (15.22) | 2.80 |
Authors | Studies |
---|---|
Dos Santos, J; Mesquita, A; Silva, DJ; Vaz, AP | 1 |
Campins, L; Camps, M; Lianes, P; Marin, S; Pérez-Cordón, L; Salvà, F | 1 |
Castan, F; Lelong, B; Maingon, P; Nougaret, S; Pezet, D; Rouanet, P; Rullier, E; Tuech, JJ | 2 |
Bi, L; Deng, X; Gou, H; He, D; He, Y; Huang, S; Meng, W; Qiu, M; Wang, Z; Wu, B; Wu, Q; Yu, Y | 1 |
Chen, B; Fang, H; Feng, YR; Hu, C; Jin, J; Li, GF; Li, N; Li, YX; Liu, LY; Liu, WY; Liu, XF; Liu, YP; Lu, NN; Qi, SN; Ren, H; Song, YW; Tang, Y; Wang, H; Wang, J; Wang, SL; Wang, WH; Wang, WL; Zhu, Y | 1 |
Bar-Sela, G; Lutsyk, M; Turgeman, I | 1 |
Alfieri, S; Barbaro, B; Boldrini, L; Chiloiro, G; Coco, C; Crucitti, A; Cusumano, D; Gambacorta, MA; Manfredi, R; Meldolesi, E; Nardini, M; Persiani, R; Petruzziello, L; Placidi, L; Ricci, R; Romano, A; Salvatore, L; Sofo, L; Valentini, V | 1 |
Eminler, AT; Hacibekiroglu, I; Karacaer, C; Koksal, AS; Toka, B; Tozlu, M; Uslan, MI | 1 |
Akutsu, D; Fukuda, S; Hagiwara, Y; Ikeda, N; Inagaki, Y; Kobayashi, M; Moriwaki, T; Narasaka, T; Niisato, Y; Onoda, T; Suzuki, H; Tange, Y; Tomisaki, R; Tsuchiya, K; Tsuji, M; Yamada, K; Yamada, T; Yamamoto, Y | 1 |
Cha, Y; Huang, W; Tian, Y; Xiong, H; Yuan, X; Zhang, H | 1 |
Aomatsu, K; Hiramatsu, S; On, O; Sugimoto, A | 1 |
Cai, S; Shen, L; Wan, J; Wang, J; Wang, Y; Wu, R; Xia, F; Xu, Y; Zhang, H; Zhang, Z | 1 |
Carballido, E; Dessureault, S; Felder, S; Frakes, J; Hoffe, S; Howard, L; Imanirad, I; Kim, J; Kim, R; Liu, Y; Malafa, M; Martinez Jimenez, ME; Mehta, R; Nixon, A; Sahin, I; Sanchez, J; Xie, H | 1 |
Kwakman, JJM; Mol, L; Punt, CJA | 1 |
Bello Crespo, M; Gajete Pablos, MA; Gioseffi, HA; Roa García, DM; Trujillano Ruiz, A | 1 |
Bello, BL; Carmichael, JC; Cataldo, P; Cercek, A; Coveler, AL; Dunne, RF; Friel, CM; Garcia-Aguilar, J; Gleisner, A; Gollub, MJ; Goodman, KA; Gregory, A; Guillem, JG; Herzig, DO; Hunt, S; Kim, JK; Krauss, J; Lee, M; Lin, S; Liska, D; Marcet, J; Nash, GM; Omer, DM; Oommen, S; Pappou, E; Patil, S; Paty, PB; Polite, B; Saltz, LB; Segal, NH; Smith, JJ; Temple, L; Ternent, C; Thompson, HM; Varma, MG; Verheij, FS; Wei, IH; Weiser, MR; Widmar, M; Wu, AJ; Yaeger, R; Yuval, JB | 1 |
Araujo, RO; Ferreira, CG; Guaraldi, S; Linhares, E; Martins, I; Thuler, LC; Torres, C; Valadão, M; Victorino, AP; Vieira, FM | 1 |
Bertrand, N; Bridoux, M; Le Deley, MC; Mirabel, X; Simon, N; Sylla, D; Turpin, A | 1 |
Doki, Y; Eguchi, H; Hata, T; Miyoshi, N; Mizushima, T; Mori, R; Ogino, T; Sekido, Y; Takahashi, H; Uemura, M | 1 |
Cho, YB; Choi, DH; Huh, JW; Jo, H; Kang, WK; Kim, HC; Kim, ST; Lee, J; Lee, WY; Lim, HY; Park, HC; Park, JO; Park, SH; Park, Y; Park, YS; Yu, JI; Yun, SH | 1 |
Cao, K; Han, J; Li, G; Qu, H; Wang, Z; Wei, G; Zhai, Z; Zhang, H | 1 |
Endo, H; Fujita, S; Kanke, Y; Kono, K; Momma, T; Okayama, H; Onozawa, H; Saito, M; Sakamoto, W; Saze, Z | 1 |
Azmy, AM; Elhawi, ME; Ghali, RRY; Gobran, NS; Shakweer, MM; Soliman, DA | 1 |
Bärtschi, D; Bastian, S; Bovet, C; Csajka, C; Decosterd, LA; Guckenberger, M; Jaehde, U; Joerger, M; Largiadèr, CR; Prost, JC; Schmulenson, E; Theurillat, R; von Moos, R | 1 |
Gao, L; Liu, X; Ma, X; Ou, K; Wang, Q; Yang, L; Zhang, H | 1 |
Burgos-Morón, E; Calderón-Montaño, JM; Díaz-Ortega, P; Guillén-Mancina, E; Jiménez-Alonso, JJ; Jiménez-González, V; López-Lázaro, M | 1 |
Begg, W; Kibudde, S | 1 |
Li, H; Lu, J; Ma, X; Ruan, Y; Wang, L; Wu, X; Xu, H; Xu, X; Zhou, S; Zhou, X | 1 |
Hasegawa, K; Ihara, K; Mizukami, S; Ohara, M; Sawada, K; Shonaka, T; Sumi, Y; Takeda, T; Tani, C; Tanino, M | 1 |
Aoyama, T; Atsumi, Y; Ju, M; Kazama, K; Numata, M; Rino, Y; Tamagawa, H; Tsuchiya, K; Yukawa, N | 1 |
Baek, JY; Beom, SH; Cha, Y; Choi, J; Choi, MK; Hong, YS; Kim, J; Kim, JE; Kim, JH; Kim, SY; Kim, TW; Lee, JS; Lim, SB; Oh, CR; Park, IJ; Park, JH | 1 |
Amellal, N; André, T; Aubel, P; Campos-Bragagnoli, A; Chmielowska, E; Csöszi, T; Falcone, A; Fougeray, R; Liposits, G; Martín, L; Moiseenko, F; Polo-Marques, E; Saunders, MP; Shparyk, Y | 1 |
Abduljabbar, A; Alhomoud, S; Alhussini, H; Aljubran, A; Almanea, H; Alsanea, N; Alshabanah, M; Alsuhaibani, A; Alzahrani, A; Ashari, L; Awad, A; Bazarbashi, S; Elashwah, A | 1 |
Artru, P; Boige, V; Clavere, P; De Bari, B; De Sousa Carvalho, N; François, E; Gal, J; Gargot, D; Lemanski, C; Magné, N; Martel-Lafay, I; Nouhaud, E; Pernot, M; Ronchin, P; Vendrely, V | 1 |
Bei, JX; Chen, G; Cheng, Y; Ding, PR; Feng, YF; Gao, YH; Ju, HX; Lei, J; Li, LR; Li, WL; Li, Y; Li, YF; Lin, JZ; Lu, ZH; Mei, WJ; Mo, XW; Pan, ZZ; Ren, YK; Sun, YM; Tang, JH; Wan, DS; Wan, XB; Wang, W; Wang, XZ; Wang, ZQ; Wu, XJ; Wu, ZG; Xiao, WW; Xie, E; Xu, DB; Yang, CK; Ye, SW; Zeng, ZF; Zhang, H; Zhang, R; Zhang, X; Zhang, XP; Zhao, JL; Zhuang, YZ | 1 |
de Back, TR; Koopman, M; Mol, L; Nagtegaal, ID; Nijman, L; Punt, CJA; Reinten, RJ; Sommeijer, DW; Ten Hoorn, S; van den Bosch, T; van Dijk, E; van Noesel, CJM; Vermeulen, L; Ylstra, B | 1 |
Chie, EK; Jang, HS; Kim, DY; Kim, SH; Kim, TH; Lee, JH; Nam, TK; Park, HC; Sung, SY | 1 |
Aravantinos, G; Dessypris, N; Gkoura, S; Karampinos, K; Mauri, D; Miaris, N; Samantas, E; Sgouros, J; Spathas, N; Stamoulis, G; Theodoropoulos, I; Tzoudas, F; Visvikis, A | 1 |
Bai, S; Cai, P; Chang, H; Chen, G; Gao, Y; Liu, S; Luo, H; Pan, Z; Wang, Q; Wang, X; Wu, X; Xiao, W; Ye, Y; Yu, H; Zeng, Z; Zhuang, Y | 1 |
Chen, CP; Chen, CY; Hsu, WH; Hu, HM; Huang, CW; Huang, MY; Shen, BN; Wang, JY; Wei, PL | 1 |
Bae, HW; Chang, JS; Cho, MS; Choi, GS; Kim, NK; Kim, TH; Koom, WS; Shin, SJ; Yang, SY | 1 |
Hannan, M; Horgan, AM; O'Driscoll, M; Sahm, LJ; Tabb, E; Walsh, DJ | 1 |
Chin, K; Matsueda, K; Nagaoka, T; Nakayama, I; Ogura, M; Ooki, A; Osumi, H; Shinozaki, E; Takahari, D; Ueno, T; Wakatsuki, T; Yamaguchi, K | 1 |
Collins, JM; Kinsella, TJ; Kunos, CA; Piekarz, R | 1 |
Alonso, V; Capdevila, J; Feliu Batlle, J; Fernandez-Martos, C; Gallego, J; García-Albéniz, X; García-Carbonero, R; Heredia-Soto, V; Layos, L; Losa, F; Machado, I; Maurel, J; Montagut, C; Nogué, M; Pericay, C; Pesántez, D; Rodríguez-Salas, N; Salud, A; Ten Hoorn, S; Vera, R; Vermeulen, L; Viñal, D | 1 |
Ding, K; Dong, C; Fang, X; Hu, H; Li, J; Liao, X; Sun, L; Wang, J; Weng, S; Xiao, Q; Xu, D; Yuan, Y; Zhang, S; Zhong, C | 1 |
Garcia-Aguilar, J; Kim, JK; Lin, ST; Omer, DM; Qin, LX; Saltz, LB; Thompson, HM; Valdivieso, SC; Verheij, FS; Wu, AJ; Yuval, JB | 1 |
Chen, J; Leng, Y; Li, F; Sun, X; Wu, C; Xu, L; Zhang, C; Zhang, D; Zhang, S | 1 |
Banchelli, I; Banzi, M; Boccaccino, A; Bonetti, AV; Carandina, I; Corbelli, J; Di Bartolomeo, M; Frassineti, GL; Gelsomino, F; Grassi, E; Marisi, G; Martella, L; Molinari, C; Nanni, O; Papiani, G; Passardi, A; Petracci, E; Pietrantonio, F; Tamberi, S; Ugolini, G; Valli, I; Zingaretti, C | 1 |
Brignoli, A; Carriero, A; Ferrara, E; Forti, L; Franco, P; Gennari, A; Krengli, M; Loi, G; Socci, C; Zannetti, M | 1 |
Fukuda, H; Hashimoto, T; Hirano, H; Ito, Y; Kanemitsu, Y; Mizusawa, J; Murofushi, K; Sasaki, K; Takashima, A; Tsukada, Y; Tsukamoto, S | 1 |
Azad, NS; Efron, J; Fang, S; Gearhart, S; Hacker-Prietz, A; Jia, AY; Meyer, J; Murphy, A; Narang, A; Safar, B; Warczynski, T; Zaheer, A | 1 |
Funamizu, N; Hiramoto, Y; Nakabayashi, Y; Tomori, K; Yanaga, K | 1 |
Huang, J; Huang, W; Li, W; Liu, G; Lv, Y; Wu, J | 1 |
Arslan, NC; Bingul, M; Birkay Gorken, I; Canda, AE; Isik, O; Kanat, O; Kurt, M; Obuz, F; Oztop, I; Ozturk, E; Terzi, C; Ugras, N; Unlu, M; Yilmazlar, T | 1 |
Buwenge, M; Coe, M; de Terlizzi, F; Ferioli, M; Galuppi, A; Guido, A; Morganti, AG; Poggioli, G | 1 |
Jankarashvili, N; Kakhadze, S; Tchiabrishvili, M; Topeshashvili, M; Turkiasvili, L | 1 |
Anderluh, F; Boc, N; Brecelj, E; Ermenc, AS; Krebs, B; Oblak, I; Omejc, M; Peressutti, AJ; Tuta, M; Velenik, V | 1 |
Janssen, S; Rades, D; Schild, SE; Treder, M | 1 |
Abengózar, M; Baixauli, J; Chopitea Ortega, A; Cienfuegos, JA; García-Consuegra, A; Hernández Lizoain, JL; Rodríguez, J; Sánchez Justicia, C | 1 |
Goldkind, L; Johnson, JT; Junga, Z; Shumar, J | 1 |
Kim, S; You, SH | 1 |
Al-Haidari, G; Åsli, LM; Dueland, S; Guren, MG; Larsen, SG; Malinen, E; Rekstad, BL; Skovlund, E; Undseth, C | 1 |
Kothandath Shankar, RK; Mufti, SS; Naik, R; Sarathy, V | 1 |
Bloemen, JG; Burger, JWA; Creemers, GJM; Kusters, M; Nederend, J; Nieuwenhuijzen, GAP; Peulen, HMU; Roef, MJ; Rutten, HJT; van Lijnschoten, G; van Zoggel, DMGI; Voogt, ELK | 1 |
Chen, C; Dai, N; Feng, Y; He, S; Li, C; Li, M; Shan, J; Wang, D; Wang, G; Xiao, H; Yang, B | 1 |
Adikrisna, R; Gokita, K; Nara, A; Onishi, I; Sueyoshi, K; Udagawa, M; Watanabe, Y | 1 |
Hata, T; Imamoto, H; Kawada, J; Kim, Y; Okano, M; Okuyama, M; Tanizaki, K; Tsujinaka, T | 1 |
Albertoni, L; Bao, QR; Campi, C; Capelli, G; Cecchin, D; Crimì, F; Florio, A; Milite Rossi, S; Pucciarelli, S; Spolverato, G; Stramare, R | 1 |
Li, M; Li, Q; Li, ZY; Liu, XJ; Song, B; Wang, XD; Xia, CC; Ye, Z; Yuan, F; Yuan, Y; Zhang, X | 1 |
Alahyari, S; Malekzadeh Moghani, M; Moradi, A; Nasiri, M | 1 |
Ikematsu, H; Ito, M; Ito, Y; Kadota, T; Kanemitsu, Y; Kushima, R; Mizutani, T; Muto, M; Ogawa, G; Saito, Y; Sasaki, T; Shitara, K | 1 |
Chen, JS; Li, KG; Liang, SX; Mo, XW; Qu, S; Tang, WZ; Wei, JB; Wu, CH; Yang, XH | 1 |
Grosek, J; Omejc, M; Tuta, M; Velenik, V; Zadnik, V | 1 |
Al-Najami, I; Cunningham, C; Jones, HJS | 1 |
Cui, M; Liu, M; Su, X; Tan, F; Xing, J; Xu, K; Yang, H; Yao, Z; Zhang, C; Zhang, N | 1 |
Christie, M; Croxford, M; Faragher, I; Gibbs, P; Guerrieri, M; Jones, IT; Kosmider, S; Lee, M; Loft, M; Steel, M; Tie, J; Wong, HL; Wong, R | 1 |
Baba, Y; Fujihira, N; Fujihira, T; Kuge, K; Matsuda, A; Matsumoto, S; Suzuki, H; Yamada, T; Yoshida, H | 1 |
Huang, D; Lin, Q; Song, J; Xu, B | 1 |
Alonso-Orduña, V; Aranda, E; Biondo, S; Capdevila, J; Escudero, P; Gallego, J; García-Paredes, B; Gómez-España, A; Grávalos, C; López, C; Losa, F; Manzano, JL; Martínez-Villacampa, M; Palacios, A; Pericay, C; Safont, MJ; Salazar, R | 1 |
Amani, Y; Asma, B; Chiraz, N; Ghorbel, A; Hajer, J; Ines, L; Rim, A | 1 |
Enomoto, M; Ishizaki, T; Kasahara, K; Katsumata, K; Mazaki, J; Nagakawa, Y; Ohno, Y; Takano, Y; Tsuchida, A; Wada, T; Watanabe, M; Yamada, E | 1 |
Bigness, A; Felder, S; Frakes, J; Hoffe, S; Imanirad, I; Laskowitz, D; Sahin, IH; Xie, H | 1 |
Akhtar, N; Bhatt, MLB; Chakrabarti, D; Gupta, R; Gupta, S; Kumar, V; Qayoom, S; Rajan, S; Srivastava, K; Verma, M | 1 |
Bali, AM; Bregni, G; Ciardiello, F; Deleporte, A; Giunta, EF; Hendlisz, A; Liberale, G; Moretti, L; Pretta, A; Sclafani, F; Troiani, T | 1 |
He, X; Li, K; Tong, S; Zheng, Y | 1 |
Anger, F; Germer, CT; Kelm, M; Klein, I; Kunzmann, V; Löb, S; Schlegel, N; Schollbach, J; Wiegering, A | 1 |
Bloemen, JG; Burger, JWA; Cnossen, JS; Creemers, GJ; Nederend, J; Nieuwenhuijzen, GAP; Peulen, HMU; Rutten, HJT; Schaap, DP; van den Berg, K; van Lijnschoten, G; Voogt, ELK; Willems, J | 1 |
Chaudry, SJ; Irfan, N; Mansha, MA; Rashid, A; Sadaf, T; Waheed, A | 1 |
Abraham, AG; Ghosh, S; Joseph, K; Mahfouz, M; Menon, A; Mulder, K; Nijjar, T; Paulson, K; Roa, W; Severin, D; Tankel, K; Thachuthara, JJ; Usmani, N; Warkentin, H | 1 |
Awawda, M; Ben Yosef, R; Gourevich, K; Lutsyk, M | 1 |
Hartman, W; Nuyttens, JJME; Oomen-de Hoop, E; Rothbarth, J; van Meerten, E; van Rees, JM; van Vugt, JLA; Verhoef, C | 1 |
Guven, DC; Yalcin, S | 1 |
Berga, N; Borras, JM; Capdevila, J; Cardona, I; Espinas, JA; Font, R; Fort, E; Layos, L; Lezcano, C; Martinez Villacampa, M; Pericay, C; Pisa, A; Solà, J; Tobeña, M | 1 |
Baratelli, C; Brown, G; Chau, I; Cunningham, D; Kalaitzaki, E; Morano, F; Rao, S; Rasheed, S; Sclafani, F; Starling, N; Tait, D; Tekkis, P; Watkins, D; Wotherspoon, A | 1 |
Czito, BG; DeLuca, A; Deming, DA; Dudley, MW; He, L; Holen, KD; Jameson, GS; Komarnitsky, P; Michael, M; Mittapalli, RK; Mulcahy, MF; Munasinghe, W; Ngan, SY; Vaghefi, H; Zalcberg, JR | 1 |
De Sanctis, V; Minniti, G; Nicosia, L; Osti, MF; Russo, I; Valeriani, M | 1 |
Beukema, JC; Bisschop, C; de Jong, KP; Gelderblom, H; Havenga, K; Hospers, GAP; Jansen, RLH; Rutten, HJT; van de Velde, CJH; van Dijk, TH; Wiggers, T | 1 |
Huo, Z; Liu, Y; Ren, J; Wang, X; Yang, G | 1 |
Bae, JM; Jang, HS; Jeong, S; Kim, SH; Lee, JH; Lee, JW; Nam, TK; Song, JH; Sung, S | 1 |
Avishek, A; Biswajit, D; Jayanthi, M | 1 |
Abdelnaby, A; Anandam, J; Arriaga, Y; Balch, G; Beg, MS; Dong, Y; Karri, S; Meyer, J; Raja, G; Syed, S; Verma, U | 1 |
Aristei, C; Chiloiro, G; De Paoli, A; Gambacorta, MA; Lupattelli, M; Macchia, G; Matrone, F; Navarria, F; Nicosia, L; Osti, M; Palazzari, E; Valentini, V | 1 |
Beare, S; Bottomley, D; Chambers, P; Essapen, S; Gollins, S; Hemmings, G; Lawrie, E; Lopes, A; Myint, AS; Quirke, P; Samuel, L; Saunders, M; Sebag-Montefiore, D; Sizer, B; Southward, K; Susnerwala, S; Taylor, M; Tinkler-Hundal, E; West, N; Worlding, J | 1 |
Higashide, S; Nio, M; Yata, Y; Yonenaga, Y | 1 |
Azria, D; Bécouarn, Y; Bedenne, L; Berdah, J; Bouché, O; Conroy, T; de La Roche, G; Denis, B; Doyen, J; Dupuis, O; Etienne, P; François, E; Gérard, J; Gourgou-Bourgade, S; Hennequin, C; Jarlier, M; Juzyna, B; Lledo, G; Mahé, M; Martel-Lafay, I; Mineur, L; Mirabel, X; Seitz, J; Vendrely, V | 1 |
Evans, T; Jootun, N; Mak, J; Makin, G; Platell, C | 1 |
Jung, SW; Kim, CW; Kim, JC; Kim, N; Lee, JL; Lim, SB; Oh, SH; Park, IJ; Yeom, SS; Yoon, YS; Yu, CS | 1 |
Chiang, CL; Lee, FAS; Lee, SF; Poon, CM; Tung, SY; Wong, FCS; Wong, YW | 1 |
DeVries, AF; Eisterer, W; Kogler, P; Öfner, D; Sölkner, L; Thaler, J | 1 |
Chen, G; Lu, SX; Lu, ZH; Pan, ZZ; Wan, DS; Wu, XJ; Zhang, RX; Zhou, ZG | 1 |
Afanas'ev, SG; Astakhova, TM; Goncharov, AL; Ivanova, EV; Kondakova, IV; Rodoman, GV; Sharova, NP; Sumedi, IR | 1 |
Beppu, N; Kimura, F; Nakamoto, Y; Okamoto, R; Tomita, N; Yamanaka, N; Yanagi, H | 1 |
Beldner, MA; Billingsley, KG; Blanke, CD; Guthrie, KA; Hezel, AF; Hochster, HS; Leichman, CG; Lenz, HJ; McDonough, SL; Smalley, SR; Velasco, MR | 1 |
Bärtschi, D; Berger, MD; Bodoky, G; Hayoz, S; Izzo, P; Klingbiel, D; Koeberle, D; Meier, UR; Plasswilm, L; Rauch, D; Roth, A; Saletti, P; Samaras, P; Schacher, S; von Moos, R; Winterhalder, RC; Yan, P; Zaugg, K; Zwahlen, D | 1 |
Begum, R; Braconi, C; Brown, G; Capdevila, J; Chau, I; Cunningham, D; De Castro, DG; Eltahir, Z; Glimelius, B; Hahne, JC; Hulkki Wilson, S; Kalaitzaki, E; Lampis, A; Lote, H; Mentrasti, G; Oates, J; Sclafani, F; Tait, D; Tarazona, N; Valeri, N; Vlachogiannis, G; Wotherspoon, A | 1 |
Egawa, C; Inatome, J; Kagawa, Y; Kato, T; Katsura, Y; Kawai, K; Masuzawa, T; Murakami, K; Murata, K; Naito, A; Ohmura, Y; Sakamato, T; Takeda, Y; Takeno, A; Tamura, S | 1 |
Hasegawa, H; Kitagawa, Y; Kitahama, K; Kojima, K; Murai, S; Oto, I; Ozawa, H; Tajima, Y; Takenoya, T; Tamura, E; Yabe, N; Yoshikawa, T | 1 |
Egawa, C; Kagawa, Y; Kato, T; Katsura, Y; Kuwahara, R; Murakami, K; Murata, K; Naito, A; Ohmura, Y; Sakamoto, T; Takeda, Y; Takeno, A; Tamura, S; Toya, K | 1 |
Feng, T; Feng, Y; Huang, Y; Jin, J; Li, H; Li, Y; Lin, D; Liu, Y; Qiao, Y; Ren, H; Song, Y; Tan, W; Wang, S; Wang, W; Yang, J; Zhang, M | 1 |
Cai, Y; Ji, JF; Li, YH; Li, ZW; Sun, YS; Wang, L; Wu, AW | 1 |
Cercek, A; Crane, CH; Garcia-Aguilar, J; Gollub, MJ; Gonen, M; Guillem, JG; Nash, GM; Paty, PB; Reidy, DL; Roxburgh, CSD; Saltz, LB; Segal, NH; Seier, K; Shia, J; Smith, JJ; Stadler, ZK; Strombom, P; Temple, LKF; Vakiani, E; Varghese, A; Weiser, MR; Wu, AJ; Yaeger, R | 1 |
Baretti, M; Bozzarelli, S; Giordano, L; Personeni, N; Pressiani, T; Rimassa, L; Santoro, A; Tronconi, MC | 1 |
Couwenberg, AM; Hoendervangers, S; Intven, MPW; van Grevenstein, WMU; Verkooijen, HM | 1 |
Fushida, S; Hayashi, H; Hirose, A; Kinoshita, J; Makino, I; Miyashita, T; Nakamura, K; Nakanuma, S; Ninomiya, I; Ohta, T; Okamoto, K; Oyama, K; Tajima, H; Takamura, H; Tokoro, T | 1 |
Bloemendal, H; Intven, M; Jacobs, L; Los, M; Siersema, PD; Smits, AB; Ten Bokkel Huinink, D; van der Vlies, E; van Lelyveld, N; Weusten, BLAM | 1 |
Anselmo, A; Benassi, M; Del Vecchio Blanco, G; Doldo, E; Formica, V; Giudice, E; Lucchetti, J; Martano, L; Morelli, C; Nardecchia, A; Orlandi, A; Portarena, I; Roselli, M; Rossi, P; Santoni, R; Sica, G; Sileri, P | 1 |
Anwar, M; Saunders, S | 1 |
Chang, H; Chen, G; Ding, PR; Gao, YH; Lu, ZH; Pan, ZZ; Wan, DS; Wang, QX; Wu, XJ; Xiao, WW; Yu, X; Zeng, ZF | 1 |
Chen, JN; Feng, T; Feng, YR; Huang, Y; Jin, J; Li, HM; Li, YX; Lin, DX; Tan, W; Wang, X; Xiao, Q; Yang, J; Zou, SM | 1 |
Chen, S; Liu, T; Liu, Y; Wang, P; Wang, X; Wu, Y | 1 |
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Ancukiewicz, M; Blaszkowsky, LS; Chen, RC; Crowley, EM; Hong, TS; Killoran, JH; Mamon, HJ; Ryan, DP; Wo, JY | 1 |
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Ebe, K; Fujita, N; Honma, K; Ikarashi, T; Ishida, M; Koide, N; Miyazawa, T | 1 |
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Cho, MJ; Kim, JS; Song, KS; Yoon, WH | 2 |
Dunst, J; Frings, S; Hinke, A; Kölling-Schlebusch, K; Reese, T; Sutter, T; Zühlke, H | 1 |
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Ernst, A; Grem, JL; Quinn, MG; Saif, MW; Thomas, RR | 1 |
Grabenbauer, GG; Hohenberger, W; Papadopoulos, T; Rödel, C; Sauer, R; Schmoll, HJ | 1 |
Couch, LS; Groteluschen, DL; Mulkerin, DL; Stewart, JA | 1 |
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Coward, J; Cunningham, D; Maisey, N | 1 |
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Almerud, A; Gubanski, M; Lideståhl, A; Lind, PA; Naucler, G | 1 |
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Jin, J; Li, N; Li, T; Li, YX; Liu, XF; Liu, YP; Song, YW; Wang, WH; Yu, ZH | 1 |
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Falk, SJ; Glynne-Jones, R; Maughan, TS; McDonald, AC; Sebag-Montefiore, D | 1 |
Chang, HJ; Choi, HS; Hong, CW; Jeong, SY; Jung, KH; Kim, DH; Kim, DW; Kim, DY; Kim, TH; Lim, SB; Park, JG; Sohn, DK | 1 |
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Fakih, MG | 1 |
Cheng, JD; Cohen, SJ; Eisenberg, D; Engstrom, P; Freedman, G; Haluszka, O; Hoffman, J; Konski, A; McGarrity, E; Meropol, NJ; Sigurdson, E; Watson, JC | 1 |
Bendell, JC; Blobe, GC; Clary, BM; Czito, BG; Fernando, NH; Honeycutt, W; Hurwitz, HI; Ludwig, KA; Mantyh, CR; Morse, MA; Pappas, TN; Tyler, DS; Willett, CG; Yu, D | 1 |
Brown, G; Chau, I; Cunningham, D; Hill, M; Massey, A; Norman, AR; Oates, J; Ross, PJ; Tait, D; Tebbutt, N; Wotherspoon, A | 1 |
Dunst, J; Glynne-Jones, R; Sebag-Montefiore, D | 1 |
Apostolakis, S; Ekonomidou, F; Tsoussis, S; Vourliotaki, I | 1 |
Fietkau, R; Foitzik, T; Klar, E; Klautke, G; Küchenmeister, U; Ludwig, K; Prall, F | 1 |
Bajetta, E; Beretta, E; Buzzoni, R; Di Bartolomeo, M; Dognini, G; Ferrario, E; Mancin, M; Mariani, L; Valvo, F | 1 |
Barten, M; Fietkau, R; Klautke, G; Prall, F; Schiffmann, L; Wöhlke, M | 1 |
Fuentes-Pradera, J; Gordón-Santiago, Mdel M; Moreno-Vega, AL; Vargas-Machuca, JC | 1 |
Brenner, B; Dreznik, Z; Dror, Y; Fenig, E; Figer, A; Idelevich, E; Loven, D; Nudelman, I; Shani, A; Stemmer, SM; Sulkes, A; Yerushalmi, R | 1 |
Fakih, MG; Lawrence, DD; Pendyala, L; Rajput, A; Rustum, YM; Smith, JL; Toth, K; Yang, GY | 1 |
Arai, Y; Doi, T; Hatake, K; Hyodo, I; Mishima, H; Nakagawa, K; Shirao, K; Takemiya, S; Takiuchi, H; Tamura, T; Yamaguchi, K | 1 |
Cho, MJ; Kim, JM; Kim, JS; Kim, KH; Li, S; Nam, JS; Song, KS; Yeo, SG; Yoon, WH | 1 |
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Brown, TD; Chang, GJ; Crane, CH; Das, P; Delclos, ME; Eng, C; Feig, BW; Hamilton, SR; Hoff, PM; Janjan, NA; Krishnan, S; Lin, EH; Morris, J; Rodriguez-Bigas, MA; Skibber, JM; Vadhan-Raj, S; Wolff, RA | 1 |
Diasio, R; Elfiky, A; Saif, MW | 1 |
Anderluh, F; Oblak, I; Strojan, P; Velenik, V; Zakotnik, B | 1 |
Jin, J; Li, N; Li, T; Li, YX; Liu, YP; Song, YW; Wang, WH | 1 |
Bhatia, S; Chang, GJ; Crane, CH; Das, P; Delclos, ME; Eng, C; Feig, BW; Hoff, PM; Janjan, NA; Krishnan, S; Lin, EH; Rodriguez-Bigas, MA; Skibber, JM; Wolff, RA | 1 |
Chang, HJ; Choi, HS; Hong, CW; Jeong, JY; Jeong, SY; Jung, KH; Kim, DW; Kim, DY; Kim, TH; Kim, YH; Lim, SB; Park, JG; Sohn, DK; Son, SH; Yun, T | 1 |
Arnold, D; Bieker, M; Ewald, H; Flentje, M; Fürst, A; Haier, J; Hellmich, G; Hermann, RM; Hipp, M; Hohenberger, W; Liersch, T; Lordick, F; Reese, T; Rödel, C; Sauer, R; Schwella, N; Sülberg, H | 1 |
Ahn, SD; Chang, HM; Choi, EK; Choi, WS; Jang, SJ; Kim, HC; Kim, JC; Kim, JH; Kim, TW; Lee, SW; Ryu, MH; Shin, SS; Yu, CS | 1 |
Boonnuch, W; Chinswangwatanakul, V; Jivapaisarnpong, P; Lertbutsayanukul, C; Lertsanguansinchai, P; Lohsiriwat, D; Lorvidhaya, V; Panichevaluk, A; Phromratanapongse, P; Rojanasakul, A; Thavichaigarn, P; Veerasarn, V | 1 |
Aydin, S; Bonny, MA; Canon, JL; Coche, JC; Coster, B; Daisne, JF; Duck, L; Haustermans, K; Honhon, B; Humblet, Y; Kartheuser, A; Kerger, J; Kirkove, C; Laurent, S; Machiels, JP; Peeters, M; Roels, S; Scalliet, P; Sempoux, C; Van Cutsem, E | 1 |
Fakih, MG; Reddy, N; Yu, J | 1 |
Grobholz, R; Hochhaus, A; Hofheinz, RD; Horisberger, K; Kähler, G; Kraus-Tiefenbacher, U; Leitner, A; Post, S; Wenz, F; Willeke, F; Willer, A | 1 |
Callahan, E; Cheng, J; Cohen, S; Freedman, GM; Hoffman, J; Konski, A; Lewis, N; Meropol, NJ; Price, R; Rogatko, A; Sigurdson, ER; Watkins-Bruner, D | 1 |
Glynne-Jones, R; Meadows, H; Wood, W | 1 |
André, T; de Gramont, A; Larsen, AK; Louvet, C; Tournigand, C | 1 |
Arbea, L; Coma-Canella, I; García-Foncillas, J; Martinez-Monge, R | 1 |
Rödel, C; Sauer, R | 1 |
Ashton, J; Bendell, JC; Blobe, GC; Czito, BG; Hurwitz, HI; Ludwig, KA; Mantyh, CR; Morse, MA; Thomas, J; Tyler, DS; Willett, CG; Yu, D | 1 |
Fakih, MG; Raman, AK | 1 |
Amichetti, M; Caraul, B; Casula, G; Deidda, MA; Dessì, M; Farci, D; Farigu, R; Lay, GC; Maxia, L; Murtas, R; Orrù, S | 1 |
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Cao, WG; Che, JF; Jin, YN; Li, H; Ma, T; Xi, WQ; Xu, HP; Zhao, R | 1 |
Cats, A; Havenga, K; Hospers, GA; Jansen, EP; Leer, JW; Marijnen, CA; Mulder, NH; Punt, CJ; Tesselaar, ME; Van de Velde, CJ; Van Krieken, HH; Wiggers, T | 1 |
Chrenko, V; Frgala, T; Kocakova, I; Krejci, E; Kubosova, K; Roubalova, E; Sefr, R; Slampa, P; Svoboda, M; Zaloudik, J | 1 |
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Ben-Josef, E; Desai, SP; El-Rayes, BF; Greenson, JK; Griffith, KA; Huang, EH; Knol, JA; McGinn, CJ; Philip, PA; Zalupski, MM | 1 |
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Byrne, P; Cooper, R; Craven, I; Crellin, A; Melcher, A; Sebag-Montefiore, D | 1 |
Fietkau, R; Foitzik, T; Klar, E; Klautke, G; Küchenmeister, U; Ludwig, K; Prall, F; Semrau, S | 1 |
Ben-Josef, E | 1 |
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45 review(s) available for capecitabine and Cancer of Rectum
Article | Year |
---|---|
Hepatitis B reactivation after oral capecitabine treatment in a rectum cancer patient with isolated anti-HBc IgG positivity.
Topics: Capecitabine; DNA, Viral; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulin G; Male; Middle Aged; Rectal Neoplasms | 2022 |
Severe Gastrointestinal Disorder Due to Capecitabine Associated with Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Literature Review.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Rectal Neoplasms | 2022 |
Locally advanced rectal cancer receiving total neoadjuvant therapy combined with nivolumab: a case report and literature review.
Topics: Adult; Aged; Capecitabine; Humans; Male; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Second Primary; Nivolumab; Rectal Neoplasms; Rectum; Young Adult | 2022 |
Literature review of imaging, pathological diagnosis, and outcomes of metachronous lung and pancreatic metastasis of cecal cancer.
Topics: Aged; Capecitabine; Carcinoembryonic Antigen; Cecal Neoplasms; Colonic Neoplasms; Humans; Lung; Male; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Rectal Neoplasms | 2022 |
A phase Ib/II trial of PEP503 (NBTXR3, radioenhancer) with radiotherapy and chemotherapy in patients with rectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Fluorouracil; Humans; Prospective Studies; Rectal Neoplasms | 2023 |
Capecitabine-Induced Ileitis during Neoadjuvant Pelvic Radio-Chemotherapy for Locally Advanced Rectal Cancer: A Case Report with Literature Review.
Topics: Capecitabine; Chemoradiotherapy; Humans; Ileitis; Neoadjuvant Therapy; Rectal Neoplasms | 2023 |
Total neoadjuvant therapy for rectal cancer: Making sense of the results from the RAPIDO and PRODIGE 23 trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Phase III as Topic; Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Rectal Neoplasms | 2021 |
Two Cases of Capecitabine-Induced Ileitis in Patients Treated with Radiochemotherapy to the Pelvis and Review of the Literature.
Topics: Adenocarcinoma; Aged; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Biopsy; Capecitabine; Chemoradiotherapy; Colonoscopy; Female; Hand-Foot Syndrome; Humans; Ileitis; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Rectum; Tomography, X-Ray Computed | 2018 |
Capecitabine-induced myopericarditis - A case report and review of literature.
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Capecitabine; Cardiotoxicity; Humans; Male; Pericarditis; Rectal Neoplasms | 2019 |
Systematic review of treatment intensification using novel agents for chemoradiotherapy in rectal cancer.
Topics: Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; ErbB Receptors; Fluorouracil; Humans; Immunotherapy; Irinotecan; Neoadjuvant Therapy; Oxaliplatin; Poly(ADP-ribose) Polymerase Inhibitors; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Rectal Neoplasms; Sorafenib | 2018 |
Capecitabine versus 5-fluorouracil in neoadjuvant chemoradiotherapy of locally advanced rectal cancer: A meta-analysis.
Topics: Anal Canal; Capecitabine; Chemoradiotherapy, Adjuvant; Clinical Studies as Topic; Fluorouracil; Humans; Neoplasm Staging; Odds Ratio; Rectal Neoplasms | 2019 |
Radiochemotherapy in rectal cancer: the role of oxaliplatin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Digestive System Surgical Procedures; Fluorouracil; Humans; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Rectal Neoplasms; Survival Rate | 2003 |
Concurrent chemoradiotherapy for squamous cell carcinoma of the rectum.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Radiation Dosage; Rectal Neoplasms; Time Factors; Treatment Outcome | 2013 |
[Advances in new chemotherapeutic drugs for preoperative chemoradiation of locally advanced rectal cancer].
Topics: Antineoplastic Agents; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2014 |
[T-cell prolymphocytic leukemia: potential diagnostic pitfalls].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chromosome Deletion; Combined Modality Therapy; Delayed Diagnosis; Diagnostic Errors; Fatal Outcome; Humans; Immunophenotyping; Leukemia, Prolymphocytic, T-Cell; Male; Neoplasms, Second Primary; Pentostatin; Rectal Neoplasms; Sezary Syndrome; Skin Neoplasms; T-Lymphocytes | 2014 |
Postoperative chemotherapy in patients with rectal cancer receiving preoperative radio(chemo)therapy: A meta-analysis of randomized trials comparing surgery ± a fluoropyrimidine and surgery + a fluoropyrimidine ± oxaliplatin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Randomized Controlled Trials as Topic; Rectal Neoplasms; Survival Rate; Watchful Waiting | 2015 |
[Long-Term Survival of a Patient with Rectal Neuroendocrine Carcinoma after Treatment with Curative Resection and Adjuvant Chemotherapy with Capecitabine].
Topics: Antimetabolites, Antineoplastic; Biopsy; Capecitabine; Carcinoma, Neuroendocrine; Chemotherapy, Adjuvant; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Prognosis; Rectal Neoplasms; Treatment Outcome | 2015 |
[Rectal squamous cell carcinoma treatment: Retrospective experience in two French university hospitals, review and proposals].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Clinical Trials as Topic; Colostomy; Combined Modality Therapy; Female; Fluorouracil; France; Hospitals, University; Humans; Male; Middle Aged; Mitomycin; Positron Emission Tomography Computed Tomography; Radiodermatitis; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies; Skin Ulcer; Survival Rate; Treatment Outcome | 2016 |
Comparison of 5-FU-based and Capecitabine-based Neoadjuvant Chemoradiotherapy in Patients With Rectal Cancer: A Meta-analysis.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Fluorouracil; Humans; Infusions, Intravenous; Neoadjuvant Therapy; Rectal Neoplasms | 2017 |
Capecitabine-induced oromandibular dystonia: a case report and literature review.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Asian People; Brain Stem; Capecitabine; Deoxycytidine; Drug Administration Schedule; Dystonia; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Mandible; Middle Aged; Mouth; Rectal Neoplasms | 2008 |
Neoadjuvant chemoradiation for rectal cancer: is more better?
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Deoxycytidine; Dose-Response Relationship, Radiation; Fluorouracil; Humans; Irinotecan; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2008 |
The role of capecitabine in the management of tumors of the digestive system.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Cholangiocarcinoma; Colonic Neoplasms; Deoxycytidine; Digestive System Neoplasms; Docetaxel; Esophageal Neoplasms; Fluorouracil; Gallbladder Neoplasms; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Taxoids; Treatment Outcome; Vascular Endothelial Growth Factor A | 2009 |
[Possibilities of resistance prediction to neoadjuvant concomitant chemoradiotherapy in the treatment algorithm of patients with rectal carcinoma].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Therapy; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2008 |
Efficacy and safety of bevacizumab plus capecitabine and irinotecan regimen for metastatic colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Disease-Free Survival; Fatigue; Female; Fluorouracil; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hypertension; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Proteins; Rectal Neoplasms; Retrospective Studies; Vascular Endothelial Growth Factor A | 2010 |
Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials.
Topics: Age Factors; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms; Remission Induction; Sex Factors | 2010 |
Cetuximab and chemoradiation for rectal cancer--is the water getting muddy?
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Deoxycytidine; ErbB Receptors; Fluorouracil; Gefitinib; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Rectal Neoplasms; Treatment Failure | 2010 |
[Difference of colon cancer and rectal cancer-from the view of an oncological physician].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Chromosomal Instability; Colonic Neoplasms; Deoxycytidine; Fluorouracil; Humans; Leucovorin; Microsatellite Instability; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Prognosis; Rectal Neoplasms; Risk Factors | 2010 |
Evolution of 5-fluorouracil-based chemoradiation in the management of rectal cancer.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Therapy; Radiation-Sensitizing Agents; Rectal Neoplasms | 2011 |
[Preoperative radiochemotherapy for rectal cancer: forecasting the next steps through ongoing and forthcoming studies].
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Forecasting; Humans; Irinotecan; Leucovorin; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Radiotherapy, Conformal; Randomized Controlled Trials as Topic; Rectal Neoplasms; Time Factors; Treatment Outcome | 2011 |
[Chemotherapy and rectal cancer].
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2011 |
The role of capecitabine in locally advanced rectal cancer treatment: an update.
Topics: Antineoplastic Agents; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Therapy; Randomized Controlled Trials as Topic; Rectal Neoplasms | 2012 |
Addisonian crisis secondary to bilateral adrenal metastases in rectal carcinoma: report of a rare case and literature review.
Topics: Addison Disease; Adenocarcinoma; Adrenal Gland Neoplasms; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms | 2013 |
Short term results of neoadjuvant chemoradiotherapy with fluoropyrimidine alone or in combination with oxaliplatin in locally advanced rectal cancer: a meta analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Prognosis; Rectal Neoplasms; Survival Rate | 2013 |
Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Camptothecin; Capecitabine; Cyclooxygenase Inhibitors; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Receptors, Growth Factor; Rectal Neoplasms | 2003 |
Combined modality treatment for rectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclooxygenase Inhibitors; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Transforming Growth Factor alpha | 2005 |
The integration of oral capecitabine into chemoradiation regimens for locally advanced rectal cancer: how successful have we been?
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Rectal Neoplasms | 2006 |
Integration of novel agents into combined-modality treatment for rectal cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Deoxycytidine; Drug Delivery Systems; Fluorouracil; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2007 |
Radiotherapy for localized rectal cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Radiotherapy Dosage; Radiotherapy, Conformal; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Rectal Neoplasms; Rectum; Survival Analysis; Treatment Outcome | 2007 |
Capecitabine vs continuous infusion 5-FU in neoadjuvant treatment of rectal cancer. A retrospective review.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorouracil; Humans; Infusions, Parenteral; Neoadjuvant Therapy; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2008 |
Combined-modality therapy for rectal cancer: future prospects.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Deoxycytidine; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Vascular Endothelial Growth Factor A | 2007 |
Capecitabine and radiotherapy as neoadjuvant treatment for rectal cancer.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorouracil; Humans; Prodrugs; Radiotherapy, Adjuvant; Rectal Neoplasms | 2007 |
Current options for the management of rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Endosonography; Fluorouracil; Humans; Leucovorin; Magnetic Resonance Imaging; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Radiotherapy, Adjuvant; Rectal Neoplasms; Tomography, Emission-Computed | 2007 |
The use of capecitabine in the combined-modality therapy for rectal cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorouracil; Humans; Leucovorin; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Thymidine Phosphorylase; Vitamin B Complex | 2008 |
[Capecitabine--a review of its antitumor activity and toxicity in clinical studies].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colonic Neoplasms; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Randomized Controlled Trials as Topic; Rectal Neoplasms | 2000 |
Improving chemoradiotherapy in rectal cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials as Topic; Deoxycytidine; Digestive System Surgical Procedures; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2001 |
227 trial(s) available for capecitabine and Cancer of Rectum
Article | Year |
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Tailored Strategy for Locally Advanced Rectal Carcinoma (GRECCAR 4): Long-term Results From a Multicenter, Randomized, Open-Label, Phase II Trial.
Topics: Capecitabine; Carcinoma; Chemoradiotherapy; Disease-Free Survival; Humans; Rectal Neoplasms; Retrospective Studies | 2022 |
Early response to upfront neoadjuvant chemotherapy (CAPOX) alone in low- and intermediate-risk rectal cancer: a single-arm phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Rectal Neoplasms; Remission Induction; Risk Factors; Treatment Outcome | 2021 |
Postoperative Chemoradiotherapy With Capecitabine and Oxaliplatin vs Capecitabine for Stage II to III Rectal Cancer: A Randomized Clinical Trial.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; China; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Postoperative Care; Rectal Neoplasms; Treatment Outcome | 2021 |
THUNDER 2: THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI guided radiotherapy.
Topics: Adult; Antineoplastic Agents; Capecitabine; Feasibility Studies; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Radiotherapy, Image-Guided; Rectal Neoplasms; Rectum; Treatment Outcome | 2022 |
Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH).
Topics: Antibodies, Monoclonal, Humanized; Capecitabine; Humans; Neoadjuvant Therapy; Oxaliplatin; Prospective Studies; Quality of Life; Rectal Neoplasms | 2022 |
Phase I Study of Lenvatinib and Capecitabine with External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma.
Topics: Adenocarcinoma; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Phenylurea Compounds; Quinolines; Rectal Neoplasms; Treatment Outcome; Vascular Endothelial Growth Factor A | 2022 |
Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Organ Preservation; Oxaliplatin; Prospective Studies; Rectal Neoplasms | 2022 |
Quality of life in a randomized trial comparing two neoadjuvant regimens for locally advanced rectal cancer-INCAGI004.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fecal Incontinence; Fluorouracil; Humans; Neoadjuvant Therapy; Quality of Life; Rectal Neoplasms | 2022 |
A Phase II Study of Preoperative Chemoradiotherapy with Capecitabine Plus Simvastatin in Patients with Locally Advanced Rectal Cancer.
Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Humans; Neoadjuvant Therapy; Neoplasm Staging; Organ Sparing Treatments; Rectal Neoplasms; Simvastatin | 2023 |
Population pharmacokinetic analyses of regorafenib and capecitabine in patients with locally advanced rectal cancer (SAKK 41/16 RECAP).
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fluorouracil; Humans; Phenylurea Compounds; Pyridines; Rectal Neoplasms | 2022 |
Preoperative Chemoradiotherapy With Capecitabine With or Without Temozolomide in Patients With Locally Advanced Rectal Cancer: A Prospective, Randomised Phase II Study Stratified by O
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Capecitabine; Chemoradiotherapy; Dacarbazine; DNA; DNA Methylation; DNA Repair Enzymes; Glioblastoma; Humans; Prospective Studies; Rectal Neoplasms; Temozolomide | 2023 |
Trifluridine-tipiracil plus bevacizumab versus capecitabine plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer ineligible for intensive therapy (SOLSTICE): a randomised, open-label phase 3 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colonic Neoplasms; Colorectal Neoplasms; Female; Humans; Male; Rectal Neoplasms; Trifluridine | 2023 |
Retrospective Evaluation of the Impact of Dose Escalation Using Pre-operative Simultaneous Integrated Boost Volumetric Modulated Arc Therapy on the Outcome of Locally Advanced Rectal Cancer Patients.
Topics: Capecitabine; Chemoradiotherapy; Disease-Free Survival; Humans; Middle Aged; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies | 2023 |
Comparison of short course radiotherapy with chemoradiotherapy for locally advanced rectal cancers in the elderly: A multicentre, randomised, non-blinded, phase 3 trial.
Topics: Activities of Daily Living; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Rectum; Treatment Outcome | 2023 |
Neoadjuvant Chemotherapy With CAPOX Versus Chemoradiation for Locally Advanced Rectal Cancer With Uninvolved Mesorectal Fascia (CONVERT): Initial Results of a Phase III Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Humans; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Treatment Outcome | 2023 |
Long-term Survival Update and Extended RAS Mutational Analysis of the CAIRO2 Trial: Addition of Cetuximab to CAPOX/Bevacizumab in Metastatic Colorectal Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Cetuximab; Colonic Neoplasms; Colorectal Neoplasms; Disease-Free Survival; Humans; Mutation; Oxaliplatin; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Rectal Neoplasms; Retrospective Studies | 2023 |
One-Week versus Two-Week Chemoradiotherapy Followed by Curative Surgery in Rectal Cancer: Long-Term Comparative Pooled Analysis of Two Prospective Multicenter Phase II Trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Rectal Neoplasms | 2023 |
Total neoadjuvant treatment to increase the clinical complete response rate for distal locally advanced rectal cancer (TESS): A study protocol of a prospective, open-label, multicenter, single-arm, phase 2 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Clinical Trials, Phase II as Topic; Fluorouracil; Humans; Multicenter Studies as Topic; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Second Primary; Oxaliplatin; Prospective Studies; Quality of Life; Rectal Neoplasms; Treatment Outcome | 2023 |
A phase Ib/II trial of PEP503 (NBTXR3, radioenhancer) with radiotherapy and chemotherapy in patients with rectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Fluorouracil; Humans; Prospective Studies; Rectal Neoplasms | 2023 |
Total neoadjuvant therapy with or without aflibercept in rectal cancer: 3-year results of GEMCAD-1402.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Recurrence | 2023 |
Sintilimab plus bevacizumab and CapeOx (BBCAPX) on first-line treatment in patients with RAS mutant, microsatellite stable, metastatic colorectal cancer: study protocol of a randomized, open-label, multicentric study.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colonic Neoplasms; Colorectal Neoplasms; Fluorouracil; Humans; Microsatellite Repeats; Multicenter Studies as Topic; Oxaliplatin; Randomized Controlled Trials as Topic; Rectal Neoplasms | 2023 |
Compliance and Toxicity of Total Neoadjuvant Therapy for Rectal Cancer: A Secondary Analysis of the OPRA Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Neoplasm Staging; Oxaliplatin; Patient Compliance; Rectal Neoplasms; Treatment Outcome | 2024 |
Phase II study of capecitabine-based concomitant chemoradiation followed by durvalumab as a neoadjuvant strategy in locally advanced rectal cancer: the PANDORA trial.
Topics: Capecitabine; Chemoradiotherapy; Diarrhea; Humans; Neoadjuvant Therapy; Prospective Studies; Rectal Neoplasms; Transaminases | 2023 |
Total neoadjuvant therapy followed by a watch-and-wait strategy for patients with rectal cancer (TOWARd): protocol for single-arm phase II/III confirmatory trial (JCOG2010).
Topics: Adolescent; Adult; Aged; Capecitabine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Middle Aged; Multicenter Studies as Topic; Neoadjuvant Therapy; Quality of Life; Rectal Neoplasms; Treatment Outcome; Young Adult | 2023 |
Sequential short-course radiation therapy and chemotherapy in the neoadjuvant treatment of rectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2019 |
Randomized controlled trial of 8 weeks' vs 12 weeks' interval between neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Rectum; Treatment Outcome | 2020 |
Feasibility of modulated electro-hyperthermia in preoperative treatment for locally advanced rectal cancer: Early phase 2 clinical results.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Feasibility Studies; Fluorouracil; Humans; Hyperthermia, Induced; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Prospective Studies; Rectal Neoplasms | 2020 |
Protocol for a single-arm confirmatory trial of adjuvant chemoradiation for patients with high-risk rectal submucosal invasive cancer after local resection: Japan Clinical Oncology Group Study JCOG1612 (RESCUE study).
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Colorectal Surgery; Disease-Free Survival; Female; Humans; Japan; Male; Multicenter Studies as Topic; Neoplasm Invasiveness; Rectal Neoplasms; Rectum | 2020 |
Influence of concurrent capecitabine based chemoradiotherapy with bevacizumab on the survival rate, late toxicity and health-related quality of life in locally advanced rectal cancer: a prospective phase II CRAB trial.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Female; Humans; Male; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Quality of Life; Rectal Neoplasms; Risk Factors; Slovenia; Survival Rate | 2020 |
Phase II randomized trial of capecitabine with bevacizumab and external beam radiation therapy as preoperative treatment for patients with resectable locally advanced rectal adenocarcinoma: long term results.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Progression-Free Survival; Rectal Neoplasms | 2020 |
Short-course radiotherapy with consolidation chemotherapy versus conventionally fractionated long-course chemoradiotherapy for locally advanced rectal cancer: randomized clinical trial.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Consolidation Chemotherapy; Developing Countries; Dose Fractionation, Radiation; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaloacetates; Patient Compliance; Prospective Studies; Rectal Neoplasms | 2021 |
Systemic Chemotherapy as Salvage Treatment for Locally Advanced Rectal Cancer Patients Who Fail to Respond to Standard Neoadjuvant Chemoradiotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Salvage Therapy | 2017 |
Safety and tolerability of veliparib combined with capecitabine plus radiotherapy in patients with locally advanced rectal cancer: a phase 1b study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Benzimidazoles; Capecitabine; Chemoradiotherapy; Diarrhea; Fatigue; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoadjuvant Therapy; Neoplasm Staging; Poly(ADP-ribose) Polymerase Inhibitors; Rectal Neoplasms | 2017 |
Short-Course Radiotherapy Followed by Neoadjuvant Bevacizumab, Capecitabine, and Oxaliplatin and Subsequent Radical Treatment in Primary Stage IV Rectal Cancer: Long-Term Results of a Phase II Study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Rectal Neoplasms; Survival Rate; Time Factors | 2017 |
Tailored Treatment Strategy for Locally Advanced Rectal Carcinoma Based on the Tumor Response to Induction Chemotherapy: Preliminary Results of the French Phase II Multicenter GRECCAR4 Trial.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Chemoradiotherapy; Digestive System Surgical Procedures; Female; France; Humans; Induction Chemotherapy; Male; Mesentery; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Rectum; Young Adult | 2017 |
A Phase I Clinical Trial of the Phosphatidylserine-targeting Antibody Bavituximab in Combination With Radiation Therapy and Capecitabine in the Preoperative Treatment of Rectal Adenocarcinoma.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studies; Dose Fractionation, Radiation; Female; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Rectal Neoplasms; Survival Rate; Young Adult | 2018 |
Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Class I Phosphatidylinositol 3-Kinases; Combined Modality Therapy; Female; Follow-Up Studies; GTP Phosphohydrolases; Humans; Irinotecan; Male; Membrane Proteins; Middle Aged; Mutation; Neoplasm Staging; Postoperative Care; Prognosis; Prospective Studies; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Rectal Neoplasms; Retrospective Studies; Survival Rate | 2017 |
Late toxicities and clinical outcome at 5 years of the ACCORD 12/0405-PRODIGE 02 trial comparing two neoadjuvant chemoradiotherapy regimens for intermediate-risk rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Survival Rate | 2017 |
Intensified preoperative chemoradiation by adding oxaliplatin in locally advanced, primary operable (cT3NxM0) rectal cancer : Impact on long-term outcome. Results of the phase II TAKO 05/ABCSG R‑02 trial.
Topics: Adenocarcinoma; Aged; Capecitabine; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms | 2018 |
Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients.
Topics: Adult; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rectal Neoplasms; Treatment Outcome | 2017 |
Early results of a phase-II study of modified short-course radiotherapy combined with capecitabine and delayed surgery for T3M0 lower rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Digestive System Surgical Procedures; Feasibility Studies; Female; Humans; Male; Middle Aged; Neoplasm Staging; Rectal Neoplasms; Survival Analysis; Time Factors; Time-to-Treatment | 2018 |
Cetuximab Combined With Induction Oxaliplatin and Capecitabine, Followed by Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer: SWOG 0713.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Proto-Oncogene Mas; Rectal Neoplasms | 2018 |
Neoadjuvant radiotherapy combined with capecitabine and sorafenib in patients with advanced KRAS-mutated rectal cancer: A phase I/II trial (SAKK 41/08).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Middle Aged; Mutation; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins p21(ras); Radiotherapy, Adjuvant; Rectal Neoplasms; Sorafenib | 2018 |
KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy, Adjuvant; Circulating Tumor DNA; Digestive System Surgical Procedures; Female; Humans; Male; Middle Aged; Mutation; Organoplatinum Compounds; Oxaliplatin; Prognosis; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Rectal Neoplasms; Treatment Outcome | 2018 |
Hemoglobin level and XRCC1 polymorphisms to select patients with locally advanced rectal cancer candidate for neoadjuvant chemoradiotherapy with concurrent capecitabine and a platinum salt.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Hemoglobins; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Polymorphism, Genetic; Predictive Value of Tests; Rectal Neoplasms; X-ray Repair Cross Complementing Protein 1 | 2018 |
Neoadjuvant oxaliplatin and capecitabine combined with bevacizumab plus radiotherapy for locally advanced rectal cancer: results of a single-institute phase II study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nausea; Neoadjuvant Therapy; Neutropenia; Oxaliplatin; Rectal Neoplasms; Vomiting; Young Adult | 2018 |
Neoadjuvant Radiotherapy with Capecitabine Plus Bevacizumab for Locally Advanced Lower Rectal Cancer: Results of a Single-institute Phase II Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms | 2018 |
Phase II trial of capecitabine plus oxaliplatin (CAPOX) as perioperative therapy for locally advanced rectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Disease-Free Survival; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxaliplatin; Perioperative Care; Prognosis; Rectal Neoplasms; Treatment Outcome | 2018 |
Induction chemotherapy, chemoradiotherapy and consolidation chemotherapy in preoperative treatment of rectal cancer - long-term results of phase II OIGIT-01 Trial.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Consolidation Chemotherapy; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Rectal Neoplasms; Slovenia; Survival Rate | 2018 |
Total neoadjuvant treatment (CAPOX plus radiotherapy) for patients with locally advanced rectal cancer with high risk factors: A phase 2 trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Risk Factors; Young Adult | 2018 |
Neoadjuvant CAPOX and bevacizumab alone for locally advanced rectal cancer: long-term results from the N-SOG 03 trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Female; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Proportional Hazards Models; Rectal Neoplasms; Risk Factors; Treatment Outcome | 2019 |
Preoperative Volumetric Modulated Arc Therapy With Simultaneous Integrated Boost for Locally Advanced Distal Rectal Cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Preoperative Care; Prognosis; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Young Adult | 2019 |
Neoadjuvant chemoradiotherapy delivered with helical tomotherapy under daily image guidance for rectal cancer patients: efficacy and safety in a large, multi-institutional series.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy, Image-Guided; Rectal Neoplasms; Tomography, X-Ray Computed; Whole Body Imaging | 2019 |
Quality of Life After Curative Resection for Rectal Cancer in Patients Treated With Adjuvant Chemotherapy Compared With Observation: Results of the Randomized Phase III SCRIPT Trial.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Female; Humans; Male; Middle Aged; Proctectomy; Quality of Life; Rectal Neoplasms; Time Factors; Treatment Outcome | 2019 |
Phase II Trial of Neoadjuvant Chemotherapy, Chemoradiotherapy, and Laparoscopic Surgery with Selective Lateral Node Dissection for Poor-Risk Low Rectal Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Laparoscopy; Leucovorin; Lymph Node Excision; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Prognosis; Prospective Studies; Rectal Neoplasms; Survival Rate | 2019 |
The INTERACT Trial: Long-term results of a randomised trial on preoperative capecitabine-based radiochemotherapy intensified by concomitant boost or oxaliplatin, for cT2 (distal)-cT3 rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Middle Aged; Oxaliplatin; Oxaloacetates; Prospective Studies; Rectal Neoplasms | 2019 |
Impact of single-nucleotide polymorphisms in DNA repair pathway genes on response to chemoradiotherapy in rectal cancer patients: Results from ACCORD-12/PRODIGE-2 phase III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; DNA Repair; Female; Gene Regulatory Networks; Germ-Line Mutation; Humans; Logistic Models; Male; Middle Aged; Oxaliplatin; Polymorphism, Single Nucleotide; Rectal Neoplasms; Survival Analysis; Treatment Outcome | 2019 |
Does Adjuvant Chemotherapy for Locally Advanced Resectable Rectal Cancer treated with Neoadjuvant Chemoradiotherapy have an impact on survival? A Single Moroccan Institute Retrospective Study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morocco; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Prognosis; Rectal Neoplasms; Retrospective Studies; Salvage Therapy; Survival Rate; Young Adult | 2019 |
A Phase I Study of Neoadjuvant Capecitabine, Oxaliplatin, and Irinotecan (XELOXIRI) in Patients with Locally Advanced Rectal Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Disease Progression; Febrile Neutropenia; Female; Humans; Irinotecan; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Rectal Neoplasms | 2019 |
Efficacy and Safety of Two Neoadjuvant Strategies With Bevacizumab in MRI-Defined Locally Advanced T3 Resectable Rectal Cancer: Final Results of a Randomized, Noncomparative Phase 2 INOVA Study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Rectal Neoplasms; Survival Rate; Young Adult | 2019 |
Chronomodulated capecitabine and adjuvant radiation in intermediate-risk to high-risk rectal cancer: a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Cystitis; Deoxycytidine; Diarrhea; Digestive System Surgical Procedures; Drug Chronotherapy; Feasibility Studies; Female; Fluorouracil; Humans; Leukopenia; Male; Middle Aged; Oxaloacetates; Proctitis; Rectal Neoplasms; Severity of Illness Index; Treatment Outcome | 2014 |
Evaluation of short-course radiotherapy followed by neoadjuvant bevacizumab, capecitabine, and oxaliplatin and subsequent radical surgical treatment in primary stage IV rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Rectum; Treatment Outcome | 2013 |
Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2013 |
Prospective phase II trial of neoadjuvant chemo-radiotherapy with Oxaliplatin and Capecitabine in locally advanced rectal cancer (XELOXART).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organ Sparing Treatments; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms | 2013 |
Phase II study of concomitant chemoradiotherapy with local hyperthermia and metronidazole for locally advanced fixed rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Hyperthermia, Induced; Male; Metronidazole; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Rectal Neoplasms; Treatment Outcome; Young Adult | 2013 |
A phase II trial of neoadjuvant IMRT-based chemoradiotherapy followed by one cycle of capecitabine for stage II/III rectal adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2013 |
Primary tumor location and bevacizumab effectiveness in patients with metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Cecum; Colon, Descending; Colon, Sigmoid; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum; Sigmoid Neoplasms; Survival; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult | 2013 |
Neoadjuvant oxaliplatin and capecitabine and bevacizumab without radiotherapy for poor-risk rectal cancer: N-SOG 03 Phase II trial.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Patient Selection; Positron-Emission Tomography; Prospective Studies; Rectal Neoplasms; Risk Assessment; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
[Impact of CCND1 A870G polymorphism on acute adverse events in postoperative rectal cancer patients treated with adjuvant concurrent chemoradiotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Cyclin D1; Deoxycytidine; Diarrhea; Female; Fluorouracil; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Polymorphism, Single Nucleotide; Postoperative Period; Prospective Studies; Rectal Neoplasms; Risk Factors | 2013 |
HER2 in high-risk rectal cancer patients treated in EXPERT-C, a randomized phase II trial of neoadjuvant capecitabine and oxaliplatin (CAPOX) and chemoradiotherapy (CRT) with or without cetuximab.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Receptor, ErbB-2; Rectal Neoplasms; Retrospective Studies; Single-Blind Method; Treatment Outcome | 2013 |
Preoperative chemoradiation therapy with capecitabine/oxaliplatin and cetuximab in rectal cancer: long-term results of a prospective phase 1/2 study.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Mutation; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Survival Analysis | 2013 |
Analysis of bevacizumab-based preoperative radiochemotherapy in patients with locally advanced rectal cancer on surgery-associated spectrum of complications.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Preoperative Care; Prognosis; Radiotherapy; Rectal Neoplasms; Retrospective Studies; Survival Rate | 2014 |
Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial.
Topics: Adenocarcinoma; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Early Termination of Clinical Trials; Erlotinib Hydrochloride; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Preoperative Care; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms | 2014 |
Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02).
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Prospective Studies; Rectal Neoplasms; Remission Induction | 2014 |
Results in the elderly with locally advanced rectal cancer from the ACCOR12/PRODIGE 2 phase III trial: tolerance and efficacy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2014 |
RAS mutations and cetuximab in locally advanced rectal cancer: results of the EXPERT-C trial.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Mutation; Organoplatinum Compounds; Oxaliplatin; ras Proteins; Rectal Neoplasms; Retrospective Studies; Sequence Analysis, DNA; Survival Analysis; Treatment Outcome | 2014 |
Concomitant boost IMRT-based neoadjuvant chemoradiotherapy for clinical stage II/III rectal adenocarcinoma: results of a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Dose Fractionation, Radiation; Feasibility Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxaloacetates; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2014 |
Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms | 2014 |
Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04.
Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organ Sparing Treatments; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2014 |
Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Dose-Response Relationship, Drug; Drug Chronotherapy; Drug Monitoring; Drug Screening Assays, Antitumor; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Severity of Illness Index; Thrombocytopenia; Treatment Outcome | 2014 |
Neoadjuvant capecitabine, bevacizumab and radiotherapy for locally advanced rectal cancer: results of a single-institute Phase I study.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Bevacizumab; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Complications; Radiotherapy Dosage; Rectal Neoplasms | 2014 |
Preoperative chemotherapy in patients with intermediate-risk rectal adenocarcinoma selected by high-resolution magnetic resonance imaging: the GEMCAD 0801 Phase II Multicenter Trial.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Humans; Magnetic Resonance Imaging; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum | 2014 |
Prediction of pathologic staging with magnetic resonance imaging after preoperative chemoradiotherapy in rectal cancer: pooled analysis of KROG 10-01 and 11-02.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Prospective Studies; Rectal Neoplasms; Sensitivity and Specificity | 2014 |
Preoperative treatment with capecitabine, cetuximab and radiotherapy for primary locally advanced rectal cancer--a phase II clinical trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Care; Prognosis; Rectal Neoplasms; Remission Induction; Survival Rate | 2014 |
Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Radiotherapy; Rectal Neoplasms; Research Design; Valproic Acid; Young Adult | 2014 |
Neoadjuvant sandwich treatment with oxaliplatin and capecitabine administered prior to, concurrently with, and following radiation therapy in locally advanced rectal cancer: a prospective phase 2 trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Consolidation Chemotherapy; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Humans; Induction Chemotherapy; Male; Middle Aged; Neoadjuvant Therapy; Oxaloacetates; Prospective Studies; Rectal Neoplasms | 2014 |
Efficacy endpoints of radiation therapy group protocol 0247: a randomized, phase 2 study of neoadjuvant radiation therapy plus concurrent capecitabine and irinotecan or capecitabine and oxaliplatin for patients with locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rectal Neoplasms; Salvage Therapy; Survival Analysis | 2015 |
Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Digestive System Surgical Procedures; Female; Fluorouracil; Follow-Up Studies; Humans; Incidence; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Netherlands; Prognosis; Radiotherapy, Adjuvant; Rectal Neoplasms; Survival Rate | 2015 |
Prospective phase II trial of nimotuzumab in combination with radiotherapy and concurrent capecitabine in locally advanced rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Prospective Studies; Radiotherapy Dosage; Rectal Neoplasms | 2015 |
Acute small-bowel toxicity during neoadjuvant combined radiochemotherapy in locally advanced rectal cancer: determination of optimal dose-volume cut-off value predicting grade 2-3 diarrhoea.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Diarrhea; Female; Follow-Up Studies; Humans; Intestine, Small; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Prospective Studies; Radiation Injuries; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Rectal Neoplasms | 2015 |
Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy, Adjuvant; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Preoperative Period; Rectal Neoplasms; Survival Analysis; Treatment Outcome | 2015 |
A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Chemoradiotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Compliance; Preoperative Period; Radiotherapy Dosage; Rectal Neoplasms; Treatment Outcome | 2015 |
CAPIRI-IMRT: a phase II study of concurrent capecitabine and irinotecan with intensity-modulated radiation therapy for the treatment of recurrent rectal cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Female; Follow-Up Studies; Humans; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pelvic Neoplasms; Prognosis; Prospective Studies; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Remission Induction; Survival Rate; Young Adult | 2015 |
Clinical complete response (cCR) after neoadjuvant chemoradiotherapy and conservative treatment in rectal cancer. Findings from the ACCORD 12/PRODIGE 2 randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum; Treatment Outcome | 2015 |
Phase II Trial of Preoperative Radiation With Concurrent Capecitabine, Oxaliplatin, and Bevacizumab Followed by Surgery and Postoperative 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX), and Bevacizumab in Patients With Locally Advanced Rectal Cancer: 5-
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2015 |
Chemoradiation, surgery and adjuvant chemotherapy versus induction chemotherapy followed by chemoradiation and surgery: long-term results of the Spanish GCR-3 phase II randomized trial†.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum | 2015 |
[Immediate results of combined therapy for local recurrences of rectal cancer].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Radiation Injuries; Rectal Neoplasms; Severity of Illness Index; Tegafur; Treatment Outcome | 2015 |
Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Fecal Incontinence; Health Status; Humans; Magnetic Resonance Imaging; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Quality of Life; Rectal Neoplasms; Rectum; Severity of Illness Index; Sexual Dysfunctions, Psychological; Surveys and Questionnaires | 2015 |
Prognostic significance of clinical and pathological stages on locally advanced rectal carcinoma after neoadjuvant chemoradiotherapy.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Postoperative Complications; Prognosis; Proportional Hazards Models; Radiotherapy, Conformal; Radiotherapy, High-Energy; Rectal Neoplasms; Young Adult | 2015 |
Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Prognosis; Prospective Studies; Rectal Neoplasms; Survival Rate | 2015 |
Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Cetuximab; Chemoradiotherapy; Combined Modality Therapy; Disease-Free Survival; Female; Genetic Markers; Genotype; Humans; Male; MicroRNAs; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins p21(ras); Rectal Neoplasms | 2015 |
NRG Oncology Radiation Therapy Oncology Group 0822: A Phase 2 Study of Preoperative Chemoradiation Therapy Using Intensity Modulated Radiation Therapy in Combination With Capecitabine and Oxaliplatin for Patients With Locally Advanced Rectal Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Quality of Life; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Survival Rate | 2015 |
Carcinoembryonic antigen has prognostic value for tumor downstaging and recurrence in rectal cancer after preoperative chemoradiotherapy and curative surgery: A multi-institutional and case-matched control study of KROG 14-12.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoembryonic Antigen; Chemoradiotherapy; Combined Modality Therapy; Epidemiologic Methods; Female; Fluorouracil; Health Facilities; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Preoperative Care; Prognosis; Rectal Neoplasms; Treatment Outcome | 2015 |
Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2015 |
Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Consolidation Chemotherapy; Disease-Free Survival; Female; Fluorouracil; Humans; Induction Chemotherapy; Leucovorin; Male; Neoadjuvant Therapy; Organ Sparing Treatments; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Quality of Life; Rectal Neoplasms | 2015 |
CoCStom trial: study protocol for a randomised trial comparing completeness of adjuvant chemotherapy after early versus late diverting stoma closure in low anterior resection for rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Leucovorin; Male; Organoplatinum Compounds; Oxaliplatin; Quality of Life; Rectal Neoplasms; Time Factors; Treatment Outcome | 2015 |
A Feasibility Study of Neoadjuvant XELOX Without Radiotherapy for Locally Advanced Lower Rectal Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma; Chemotherapy, Adjuvant; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Humans; Japan; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Neoplasm, Residual; Oxaloacetates; Pilot Projects; Prospective Studies; Rectal Neoplasms; Time Factors; Treatment Outcome; Young Adult | 2016 |
Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Treatment Outcome | 2016 |
Early results of multicenter phase II trial of perioperative oxaliplatin and capecitabine without radiotherapy for high-risk rectal cancer: CORONA I study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Rectal Neoplasms; Risk; Treatment Outcome | 2016 |
Management of liver metastases in colorectal cancer patients: A retrospective case-control study of systemic therapy versus liver resection.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Case-Control Studies; Cetuximab; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Survival Analysis | 2016 |
Interim analysis of postoperative chemoradiotherapy with capecitabine and oxaliplatin versus capecitabine alone for pathological stage II and III rectal cancer: a randomized multicenter phase III trial.
Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Young Adult | 2016 |
Preoperative chemoradiation with capecitabine for rectal cancer in elderly patients: a phase I trial.
Topics: Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Humans; Neoplasm Staging; Preoperative Care; Rectal Neoplasms; Tomography, X-Ray Computed | 2016 |
Phase II Study of Preoperative Capecitabine and Oxaliplatin-based Intensified Chemoradiotherapy With or Without Induction Chemotherapy in Patients With Locally Advanced Rectal Cancer and Synchronous Liver-limited Resectable Metastases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Follow-Up Studies; Hepatectomy; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Rectal Neoplasms; Remission Induction; Risk Assessment; Statistics, Nonparametric; Survival Analysis; Treatment Outcome | 2016 |
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Time Factors; Treatment Outcome | 2016 |
Phase 1 Study of Preoperative Chemoradiation Therapy With Temozolomide and Capecitabine in Patients With Locally Advanced Rectal Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Dacarbazine; Female; Humans; Leukopenia; Male; Middle Aged; Nausea; Preoperative Care; Rectal Neoplasms; Temozolomide; Treatment Outcome; Vomiting | 2016 |
Capecitabine and Oxaliplatin Prior and Concurrent to Preoperative Pelvic Radiotherapy in Patients With Locally Advanced Rectal Cancer: Long-Term Outcome.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Digestive System Surgical Procedures; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Treatment Outcome | 2017 |
Acute Toxicity and Tumor Response in Locally Advanced Rectal Cancer After Preoperative Chemoradiation Therapy With Shortening of the Overall Treatment Time Using Intensity-Modulated Radiation Therapy With Simultaneous Integrated Boost: A Phase 2 Trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neoplasm Staging; Organ Sparing Treatments; Preoperative Period; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Time Factors | 2016 |
Capecitabine and Oxaliplatin Before, During, and After Radiotherapy for High-Risk Rectal Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Radiotherapy, Intensity-Modulated; Rectal Neoplasms | 2017 |
Preoperative capecitabine and accelerated intensity-modulated radiotherapy in locally advanced rectal cancer: a phase II trial.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Diarrhea; Disease-Free Survival; Feasibility Studies; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Premedication; Prospective Studies; Radiotherapy Dosage; Radiotherapy, Adjuvant; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Remission Induction | 2008 |
Phase II study of weekly intravenous oxaliplatin combined with oral daily capecitabine and radiotherapy with biologic correlates in neoadjuvant treatment of rectal adenocarcinoma.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capecitabine; Combined Modality Therapy; Deoxycytidine; DNA-Binding Proteins; Drug Administration Schedule; Endonucleases; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
A modern regimen of pre-operative concurrent chemo-radiation therapy in locally advanced rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prodrugs; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Survival Rate; Treatment Outcome | 2008 |
[Clinical observation of XELOX (Capecitabine puls Oxaliplatin): an adjuvant chemotherapy regimen used in stage III colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colonic Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Proportional Hazards Models; Rectal Neoplasms; Retrospective Studies; Survival Rate; Young Adult | 2008 |
Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Colorectal Neoplasms; Deoxycytidine; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Quality of Life; Rectal Neoplasms; Survival Analysis; Time Factors | 2009 |
Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Modality Therapy; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Laparoscopy; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Survival Analysis | 2009 |
Neoadjuvant capecitabine combined with standard radiotherapy in patients with locally advanced rectal cancer: mature results of a phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Proctocolectomy, Restorative; Radiotherapy Planning, Computer-Assisted; Rectal Neoplasms; Rectum | 2008 |
Preoperative concomitant radiotherapy with oral capecitabine in advanced rectal cancer within 6 cm from anal verge.
Topics: Administration, Oral; Adult; Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Patient Compliance; Preoperative Care; Rectal Neoplasms; Survival Analysis; Treatment Outcome | 2009 |
Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Combined Modality Therapy; Deoxycytidine; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leukopenia; Lymphatic Metastasis; Male; Middle Aged; Nausea; Proctitis; Rectal Neoplasms; Remission Induction; Vomiting | 2009 |
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Digestive System Surgical Procedures; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Conformal; Rectal Neoplasms; Time Factors; Treatment Outcome | 2009 |
Capecitabine initially concomitant to radiotherapy then perioperatively administered in locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Prospective Studies; Rectal Neoplasms; Remission Induction | 2009 |
Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer.
Topics: Activities of Daily Living; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fatigue; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Pain; Prospective Studies; Rectal Neoplasms; Remission Induction; Sleep Stages; Young Adult | 2009 |
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Capecitabine; Cetuximab; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression; Humans; Neoplasm Staging; Prognosis; Radiotherapy Dosage; Rectal Neoplasms; Treatment Outcome | 2009 |
Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Surgical Wound Dehiscence | 2010 |
Surgical treatment for locally advanced lower third rectal cancer after neoadjuvent chemoradiation with capecitabine: prospective phase II trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Endosonography; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Rectal Neoplasms | 2009 |
Preoperative downstaging chemoradiation with concurrent irinotecan and capecitabine in MRI-defined locally advanced rectal cancer: a phase I trial (NWCOG-2).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Middle Aged; Rectal Neoplasms | 2009 |
A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Celecoxib; Deoxycytidine; Diarrhea; Fecal Incontinence; Female; Fluorouracil; Gangrene; Gastrointestinal Diseases; Humans; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Proctitis; Pyrazoles; Radiation Injuries; Radiation-Sensitizing Agents; Rectal Neoplasms; Sulfonamides | 2010 |
A phase II trial of neoadjuvant capecitabine combined with hyperfractionated accelerated radiation therapy in locally advanced rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Diarrhea; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Prodrugs; Radiotherapy, Conformal; Rectal Neoplasms; Remission Induction; Treatment Outcome | 2010 |
A phase II study of cetuximab, capecitabine and radiotherapy in neoadjuvant treatment of patients with locally advanced resectable rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Capecitabine; Cetuximab; Colectomy; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; ErbB Receptors; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prodrugs; Prospective Studies; Rectal Neoplasms; Treatment Outcome | 2010 |
Phase II, randomized study of concomitant chemoradiotherapy followed by surgery and adjuvant capecitabine plus oxaliplatin (CAPOX) compared with induction CAPOX followed by concomitant chemoradiotherapy and surgery in magnetic resonance imaging-defined, l
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Medication Adherence; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Risk Assessment; Spain; Time Factors; Treatment Outcome | 2010 |
Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Survival Analysis | 2010 |
Neo-adjuvant chemo-radiation of rectal cancer with volumetric modulated arc therapy: summary of technical and dosimetric features and early clinical experience.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Carcinoma; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiometry; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Rectal Neoplasms | 2010 |
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms | 2010 |
Preoperative capecitabine and pelvic radiation in locally advanced rectal cancer--is it equivalent to 5-FU infusion plus leucovorin and radiotherapy?
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Male; Matched-Pair Analysis; Middle Aged; Mitomycin; Neoadjuvant Therapy; Preoperative Care; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Retrospective Studies; Survival Rate; Therapeutic Equivalency | 2010 |
Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/leucovorin plus oxaliplatin (FOLFOX-6) as first-line treatment for metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Treatment Outcome; Young Adult | 2011 |
Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; DNA; Female; Fluorouracil; Genotype; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mutation; Neoadjuvant Therapy; Neoplasm Staging; Pharmacogenetics; Polymerase Chain Reaction; Polymorphism, Genetic; Predictive Value of Tests; Radiotherapy, Adjuvant; Rectal Neoplasms; Thymidylate Synthase; Treatment Outcome | 2010 |
Bevacizumab, capecitabine, amifostine, and preoperative hypofractionated accelerated radiotherapy (HypoArc) for rectal cancer: a Phase II study.
Topics: Adult; Aged; Aged, 80 and over; Amifostine; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Radiography; Rectal Neoplasms; Young Adult | 2011 |
Preoperative chemoradiation with irinotecan and capecitabine in patients with locally advanced resectable rectal cancer: long-term results of a Phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Modality Therapy; Confidence Intervals; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Preoperative Period; Rectal Neoplasms; Remission Induction; Survival Rate | 2011 |
High-dose-rate intraluminal brachytherapy during preoperative chemoradiation for locally advanced rectal cancers.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Brachytherapy; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Care; Rectal Neoplasms; Young Adult | 2010 |
Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: a multicenter Phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Mutation; Neoplasm Staging; Preoperative Care; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Radiotherapy Dosage; ras Proteins; Rectal Neoplasms; Remission Induction | 2011 |
Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine; Digestive System Surgical Procedures; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Time | 2010 |
KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Genes, ras; Humans; Irinotecan; Male; Middle Aged; Mutation; Neoplasm Staging; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction | 2011 |
Preoperative radiotherapy with capecitabine and mitomycin C in locally advanced rectal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Mitomycin; Prospective Studies; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Survival; Treatment Outcome | 2011 |
Preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with newly diagnosed, primary operable, cT₃NxM0, low rectal cancer: a phase II study.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Conformal; Rectal Neoplasms; Treatment Outcome | 2011 |
Randomized phase 3 trial comparing preoperative and postoperative chemoradiotherapy with capecitabine for locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Period; Preoperative Period; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2011 |
A pilot feasibility study of TNFerade™ biologic with capecitabine and radiation therapy followed by surgical resection for the treatment of rectal cancer.
Topics: Adult; Capecitabine; Combined Modality Therapy; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Genetic Therapy; Humans; Male; Middle Aged; Neoadjuvant Therapy; Pilot Projects; Rectal Neoplasms; Tumor Necrosis Factor-alpha | 2010 |
Addition of bevacizumab to XELOX induction therapy plus concomitant capecitabine-based chemoradiotherapy in magnetic resonance imaging-defined poor-prognosis locally advanced rectal cancer: the AVACROSS study.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Oxaloacetates; Rectal Neoplasms; Treatment Outcome | 2011 |
Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: a phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Colorectal Surgery; Combined Modality Therapy; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Period; Rectal Neoplasms; Time Factors | 2012 |
Oral glutamine supplementation during preoperative radiochemotherapy in patients with rectal cancer: a randomised double blinded, placebo controlled pilot study.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemical Phenomena; Chemoradiotherapy, Adjuvant; Deoxycytidine; Diarrhea; Dietary Supplements; Double-Blind Method; Female; Fluorouracil; Gastrointestinal Tract; Glutamine; Humans; Incidence; Male; Middle Aged; Patient Dropouts; Pilot Projects; Preoperative Period; Rectal Neoplasms; Severity of Illness Index | 2011 |
Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer--a two stage phase II clinical trial.
Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Treatment Outcome | 2012 |
A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms; Treatment Outcome | 2012 |
Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer.
Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Rectal Neoplasms | 2012 |
A phase II study of neoadjuvant chemoradiotherapy with oxaliplatin and capecitabine for rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms | 2011 |
T3+ and T4 rectal cancer patients seem to benefit from the addition of oxaliplatin to the neoadjuvant chemoradiation regimen.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Rectal Neoplasms; Survival Rate; Treatment Outcome | 2012 |
Preoperative radiotherapy combined with capecitabine chemotherapy in Chinese patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; China; Cohort Studies; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Survival Rate; Treatment Outcome | 2011 |
Phase II trial of neoadjuvant chemotherapy with XELOX plus bevacizumab for locally advanced rectal cancer.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Neoadjuvant Therapy; Oxaloacetates; Rectal Neoplasms; Research Design; Treatment Outcome | 2011 |
Neoadjuvant capecitabine, radiotherapy, and bevacizumab (CRAB) in locally advanced rectal cancer: results of an open-label phase II study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Radiotherapy; Rectal Neoplasms; Regression Analysis; Research Design; Safety; Time Factors | 2011 |
[Effectiveness of neoadjuvant chemoradiotherapy of locally advanced rectal cancer in conjunction with local hyperthermia and metronidazole].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Intravenous; Male; Metronidazole; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2011 |
Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: a phase II trial.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Survival Rate; Treatment Outcome | 2012 |
Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cohort Studies; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Observation; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Treatment Outcome | 2011 |
Four-week neoadjuvant intensity-modulated radiation therapy with concurrent capecitabine and oxaliplatin in locally advanced rectal cancer patients: a validation phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Diarrhea; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Patient Compliance; Preoperative Care; Proctitis; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2012 |
A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Rectal Neoplasms; Treatment Outcome | 2012 |
Phase II trial of concomitant neoadjuvant chemotherapy with oxaliplatin and capecitabine and intensity-modulated radiotherapy (IMRT) in rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Carcinoembryonic Antigen; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Oxaloacetates; Radiotherapy, Intensity-Modulated; Rectal Neoplasms | 2012 |
Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; DNA Mutational Analysis; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Treatment Outcome | 2012 |
Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C).
Topics: Adenocarcinoma; Adult; Aged; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Chemoradiotherapy, Adjuvant; Colectomy; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Intestinal Mucosa; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Radiotherapy, Adjuvant; Rectal Neoplasms; Risk Assessment; Survival Analysis; Treatment Outcome; United Kingdom | 2012 |
Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cross-Over Studies; Deoxycytidine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Germany; Humans; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Patient Selection; Radiotherapy Dosage; Rectal Neoplasms; Risk Assessment; Survival Analysis; Treatment Outcome | 2012 |
Comparison of magnetic resonance imaging and histopathological response to chemoradiotherapy in locally advanced rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Confidence Intervals; Deoxycytidine; Female; Fluorouracil; Humans; Logistic Models; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Observer Variation; Odds Ratio; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2012 |
Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thymidine Phosphorylase; Treatment Outcome | 2012 |
KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Class I Phosphatidylinositol 3-Kinases; Deoxycytidine; Drug Administration Schedule; ErbB Receptors; Female; Fluorouracil; Genes, ras; Humans; Irinotecan; Male; Middle Aged; Mutation; Phosphatidylinositol 3-Kinases; Preoperative Care; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Radiotherapy Dosage; Rectal Neoplasms; Treatment Outcome | 2013 |
Phase II study of preoperative radiotherapy and concomitant weekly intravenous oxaliplatin combined with oral capecitabine for stages II-III rectal cancer.
Topics: Administration, Intravenous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2012 |
Multicenter phase II clinical trial of preoperative capecitabine with concurrent radiotherapy in patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease Progression; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Preoperative Period; Rectal Neoplasms; Treatment Outcome | 2013 |
Capecitabine-associated hand-foot-skin reaction is an independent clinical predictor of improved survival in patients with colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Hand-Foot Syndrome; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prospective Studies; Rectal Neoplasms; Treatment Outcome | 2012 |
Clinical outcome of the ACCORD 12/0405 PRODIGE 2 randomized trial in rectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Rectal Neoplasms; Treatment Outcome | 2012 |
Neoadjuvant chemoradiotherapy with or without panitumumab in patients with wild-type KRAS, locally advanced rectal cancer (LARC): a randomized, multicenter, phase II trial SAKK 41/07.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Diarrhea; DNA Mutational Analysis; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Panitumumab; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Treatment Outcome | 2013 |
A prospective pilot study of target-guided personalized chemotherapy with intensity-modulated radiotherapy in patients with early rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Deoxycytidine; DNA Topoisomerases, Type I; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Molecular Targeted Therapy; Mutation; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Phosphatidylinositol 3-Kinases; Pilot Projects; Precision Medicine; Prospective Studies; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Radiotherapy, Intensity-Modulated; ras Proteins; Rectal Neoplasms; Treatment Outcome | 2014 |
Phase 2 study of preoperative radiation with concurrent capecitabine, oxaliplatin, and bevacizumab followed by surgery and postoperative 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX), and bevacizumab in patients with locally advanced rectal cancer: ECO
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Postoperative Period; Radiotherapy Dosage; Rectal Neoplasms; Survival Analysis | 2013 |
Phase II trial of first-line chemoradiotherapy with intensity-modulated radiation therapy followed by chemotherapy for synchronous unresectable distant metastases rectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2013 |
Is the standardized uptake value of FDG-PET/CT predictive of pathological complete response in locally advanced rectal cancer treated with capecitabine-based neoadjuvant chemoradiation?
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Male; Middle Aged; Multimodal Imaging; Multivariate Analysis; Neoadjuvant Therapy; Positron-Emission Tomography; Predictive Value of Tests; Prognosis; Prospective Studies; Radiopharmaceuticals; Rectal Neoplasms; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Germany; Humans; Male; Maximum Tolerated Dose; Middle Aged; Pilot Projects; Prodrugs; Radiotherapy Dosage; Rectal Neoplasms; Treatment Outcome | 2002 |
Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operable rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms | 2003 |
Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Rectal Neoplasms | 2003 |
[Combined preoperative xeloda and radiotherapy for lower rectal cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Postoperative Complications; Radiotherapy; Rectal Neoplasms | 2003 |
A pilot phase II study of capecitabine in advanced or recurrent colorectal cancer.
Topics: Administration, Oral; Aged; Anorexia; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplasms; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Hyperbilirubinemia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Rectal Neoplasms | 2004 |
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Patient Selection; Rectal Neoplasms | 2004 |
Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Feasibility Studies; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Neoadjuvant Therapy; Radiation-Sensitizing Agents; Rectal Neoplasms; Treatment Outcome | 2005 |
Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer.
Topics: Adolescent; Adult; Aged; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Middle Aged; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage; Rectal Neoplasms | 2005 |
Noninvasive magnetic resonance thermography of recurrent rectal carcinoma in a 1.5 Tesla hybrid system.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Hyperthermia, Induced; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Temperature; Thermography | 2005 |
Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Diarrhea; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Male; Middle Aged; Neutropenia; Prodrugs; Rectal Neoplasms; Remission Induction; Survival Rate; Topoisomerase I Inhibitors; Treatment Outcome | 2005 |
Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Injections, Intravenous; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Rectal Neoplasms; Treatment Outcome | 2005 |
A phase I study of concurrent radiotherapy and capecitabine as adjuvant treatment for operable rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms | 2006 |
Capecitabine in combination with preoperative radiation therapy in locally advanced, resectable, rectal cancer: a multicentric phase II study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Patient Compliance; Preoperative Care; Rectal Neoplasms | 2006 |
A phase I dose escalation study of continuous oral capecitabine in combination with oxaliplatin and pelvic radiation (XELOX-RT) in patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pelvis; Preoperative Care; Rectal Neoplasms; Survival Rate | 2006 |
Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; ErbB Receptors; Female; Fluorouracil; Gefitinib; Humans; Male; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Quinazolines; Radiotherapy, Adjuvant; Rectal Neoplasms | 2006 |
Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Risk Assessment; Survival Analysis; Treatment Outcome | 2006 |
Comparison of the efficacy of oral capecitabine versus bolus 5-FU in preoperative radiotherapy of locally advanced rectal cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Diarrhea; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Leukopenia; Male; Middle Aged; Neoplasm Staging; Postoperative Complications; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2006 |
Concurrent chemoradiation with capecitabine and weekly irinotecan as preoperative treatment for rectal cancer: results from a phase I/II study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Treatment Outcome | 2006 |
A Phase I study of weekly intravenous oxaliplatin in combination with oral daily capecitabine and radiation therapy in the neoadjuvant treatment of rectal adenocarcinoma.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); DNA Repair; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Thymidine Phosphorylase; Thymidylate Synthase | 2006 |
A phase II Study of the global dose and schedule of capecitabine in Japanese patients with metastatic colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Administration Schedule; Endpoint Determination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Rectal Neoplasms | 2006 |
Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Deoxycytidine; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Radiotherapy Dosage; Rectal Neoplasms | 2006 |
Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rectal Neoplasms | 2006 |
Capecitabine as a radiosensitizing agent in neoadjuvant treatment of locally advanced resectable rectal cancer: prospective phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rectal Neoplasms | 2006 |
[Phase I study of postoperative concurrent chemoradiation with capecitabine as adjuvant treatment for stage II/III operable rectal cancer].
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Postoperative Care; Radiotherapy, Adjuvant; Radiotherapy, Conformal; Rectal Neoplasms; Rectum | 2006 |
Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Remission Induction; Treatment Outcome | 2007 |
Preoperative capecitabine with pelvic radiotherapy for locally advanced rectal cancer (phase I trial).
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Prognosis; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2006 |
Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Radiotherapy, Conformal; Rectal Neoplasms | 2007 |
A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms | 2007 |
Phase I trial of preoperative hypofractionated intensity-modulated radiotherapy with incorporated boost and oral capecitabine in locally advanced rectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Intraoperative Period; Male; Maximum Tolerated Dose; Middle Aged; Photons; Quality of Life; Radiotherapy, Intensity-Modulated; Rectal Neoplasms | 2007 |
Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: Phase I trial results.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Diarrhea; Fatigue; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Treatment Outcome | 2007 |
Preoperative chemoradiotherapy with capecitabine and oxaliplatin in locally advanced rectal cancer. A phase I-II multicenter study of the Dutch Colorectal Cancer Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Particle Accelerators; Quality of Life; Radiotherapy Dosage; Rectal Neoplasms; Rectum | 2007 |
A phase II study of preoperative capecitabine and radiation therapy in patients with rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Preoperative Care; Rectal Neoplasms; Treatment Outcome | 2007 |
Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Combined Modality Therapy; Deoxycytidine; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiotherapy; Rectal Neoplasms | 2008 |
Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease Progression; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Neoplasm Staging; Patient Compliance; Patient Selection; Preoperative Care; Rectal Neoplasms; Treatment Outcome | 2007 |
Intensified irinotecan-based neoadjuvant chemoradiotherapy in rectal cancer: four consecutive designed studies to minimize acute toxicity and to optimize efficacy measured by pathologic complete response.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prospective Studies; Rectal Neoplasms | 2007 |
Phase I-II trial of concurrent capecitabine and oxaliplatin with preoperative intensity-modulated radiotherapy in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Radiotherapy, Conformal; Rectal Neoplasms; Treatment Outcome | 2008 |
Integrating microarray and proteomics data to predict the response on cetuximab in patients with rectal cancer.
Topics: Algorithms; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Artificial Intelligence; Capecitabine; Cetuximab; Combined Modality Therapy; Computational Biology; Data Interpretation, Statistical; Databases, Factual; Deoxycytidine; Fluorouracil; Humans; Least-Squares Analysis; Models, Statistical; Oligonucleotide Array Sequence Analysis; Proteomics; Rectal Neoplasms | 2008 |
Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Pelvis; Rectal Neoplasms | 2008 |
Capecitabine, irinotecan, oxaliplatin (CAPIRINOX) and concomitant irradiation in advanced rectal cancer: the Lyon R-02-01 phase I trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Feasibility Studies; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Conformal; Rectal Neoplasms | 2008 |
Preoperative treatment combining capecitabine with radiation therapy in rectal cancer: a GERCOR Phase II Study.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Prodrugs; Radiotherapy Dosage; Rectal Neoplasms; Survival Rate | 2007 |
Phase I study of oxaliplatin in combination with capecitabine and radiotherapy as postoperative treatment for stage II and III rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Pyridines; Radiotherapy; Rectal Neoplasms | 2008 |
294 other study(ies) available for capecitabine and Cancer of Rectum
Article | Year |
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Rectal mixed adenoneuroendocrine carcinoma: Case report.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fatal Outcome; Humans; Male; Mixed Tumor, Malignant; Neuroendocrine Tumors; Oxaliplatin; Radiotherapy; Rectal Neoplasms; Rectum | 2021 |
Cost-minimisation analysis of rectal cancer neoadjuvant chemoradiotherapy based on fluoropyrimidines (capecitabine versus 5-fluorouracil).
Topics: Capecitabine; Fluorouracil; Humans; Neoadjuvant Therapy; Rectal Neoplasms; Retrospective Studies | 2021 |
Rapid Initiation of Neoadjuvant Chemoradiotherapy After Diagnosis is Associated With Improved Pathologic Response in Locally Advanced Rectal Cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Retrospective Studies; Time-to-Treatment; Treatment Outcome | 2022 |
Efficacy and safety analysis of bevacizumab combined with capecitabine in the maintenance treatment of RAS-mutant metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Carcinoembryonic Antigen; Colonic Neoplasms; Colorectal Neoplasms; Disease-Free Survival; Fluorouracil; Humans; Rectal Neoplasms; Retrospective Studies | 2022 |
[A Case of Rectal Cancer and Multiple Lung Metastases That Had Complete Response Treated by XELOX plus Bevacizumab after Primary Lesion Resection].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Female; Fluorouracil; Humans; Lung Neoplasms; Middle Aged; Oxaloacetates; Rectal Neoplasms | 2022 |
Long-Term Safety Data on S-1 Administered After Previous Intolerance to Capecitabine-Containing Systemic Treatment for Metastatic Colorectal Cancer.
Topics: Capecitabine; Cardiotoxicity; Colonic Neoplasms; Colorectal Neoplasms; Fluorouracil; Hand-Foot Syndrome; Humans; Prospective Studies; Rectal Neoplasms | 2022 |
Conjunctivitis associated with capecitabine treatment in a patient with colon cancer: The importance on educating patients into identifying adverse reactions.
Topics: Aged, 80 and over; Capecitabine; Colonic Neoplasms; Conjunctivitis; Fluorouracil; Humans; Male; Rectal Neoplasms | 2022 |
Effects of Proton Pump Inhibitors Intake During Chemoradiotherapy for Rectal Cancer: a Retrospective Cohort Study.
Topics: Capecitabine; Chemoradiotherapy; Female; Humans; Male; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Proton Pump Inhibitors; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2023 |
Impact of total neoadjuvant therapy consisting of consolidation chemotherapy on locally advanced rectal cancer survival.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Consolidation Chemotherapy; Humans; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Second Primary; Oxaliplatin; Rectal Neoplasms; Retrospective Studies | 2022 |
Short-term outcomes of neoadjuvant chemotherapy with capecitabine plus oxaliplatin for patients with locally advanced rectal cancer followed by total or tumor-specific mesorectal excision with or without lateral pelvic lymph node dissection.
Topics: Capecitabine; Humans; Lymph Node Excision; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2022 |
Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before surgery in patients with locally advanced rectal cancer.
Topics: Capecitabine; Chemoradiotherapy; Humans; Induction Chemotherapy; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Oxaliplatin; Rectal Neoplasms | 2022 |
Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colonic Neoplasms; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Longitudinal Studies; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies | 2022 |
Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer.
Topics: Amino Acids; Animals; Capecitabine; Colonic Neoplasms; Cysteine; Diet; Mice; Rectal Neoplasms | 2022 |
Capecitabine plus oxaliplatin in the treatment of metastatic colorectal cancer at Tygerberg Hospital: a retrospective study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Fluorouracil; Hospitals; Humans; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies | 2022 |
A case of percutaneous transhepatic stomal varices embolization and partial splenic artery embolization for rectal cancer after CAPOX/BEV chemotherapy: the summary of the stomal varices related to oxaliplatin administration.
Topics: Adult; Bevacizumab; Capecitabine; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Male; Neoplasm Recurrence, Local; Oxaliplatin; Rectal Neoplasms; Splenic Artery; Splenomegaly; Thrombocytopenia; Treatment Outcome; Varicose Veins | 2023 |
[A Case of Rectal Cancer with Brain and Skin Metastasis with Long-Term Survival Managed by Multidisciplinary Therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain; Capecitabine; Fluorodeoxyglucose F18; Humans; Irinotecan; Male; Positron Emission Tomography Computed Tomography; Rectal Neoplasms | 2022 |
Incidence of Disease Recurrence in Patients With Colon and Upper Rectum Adenocarcinoma Stage II and III Receiving Adjuvant Capecitabine Monotherapy: Do Number of Chemotherapy Cycles and Relative Dose Intensity of the Drug Play a Role?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colon; Fluorouracil; Humans; Incidence; Neoplasm Staging; Rectal Neoplasms; Rectum; Recurrence | 2023 |
Short-Term Outcomes and Cost-Effectiveness between Long-Course Chemoradiation and Short-Course Radiotherapy for Locally Advanced Rectal Cancer.
Topics: Asian People; Capecitabine; Chemoradiotherapy; Cost-Benefit Analysis; Humans; Neoplasms, Second Primary; Proctectomy; Radiotherapy; Rectal Neoplasms | 2023 |
Comprehensive pharmacological geriatric assessment compared to usual care in an older adult with cancer in the absence of polypharmacy.
Topics: Aged; Capecitabine; Cholinergic Antagonists; Geriatric Assessment; Humans; Inappropriate Prescribing; Male; Pharmacists; Polypharmacy; Rectal Neoplasms | 2023 |
Morphological response and tumor shrinkage as predictive factors in metastatic colorectal cancer treated with first-line capecitabine, oxaliplatin, and bevacizumab.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colonic Neoplasms; Colorectal Neoplasms; Humans; Liver Neoplasms; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2023 |
A case report of typhlitis during novel use of ropidoxuridine-capecitabine-radiotherapy for treatment-naïve rectal cancer.
Topics: Adenocarcinoma; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Female; Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Typhlitis | 2023 |
Neoadjuvant chemoradiotherapy with capecitabine based regimen in locally advanced rectal cancer: A retrospective study.
Topics: Capecitabine; Chemotherapy, Adjuvant; Humans; Neoadjuvant Therapy; Neoplasms, Second Primary; Rectal Neoplasms; Retrospective Studies | 2023 |
[Subcutaneous Metastasis from Rectal Carcinoma after Low Anterior Resection-A Case Report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Oxaliplatin; Rectal Neoplasms; Subcutaneous Tissue | 2019 |
Chemoradiotherapy with Concurrent Regional Arterial Chemotherapy for Locally Bulky Unresectable Rectal Cancer: A Case Series.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Digestive System Surgical Procedures; Feasibility Studies; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaloacetates; Rectal Neoplasms; Retrospective Studies; Survival Analysis; Treatment Outcome | 2019 |
Anorectal adenocarcinoma recurrence successfully treated with electrochemotherapy: a case report.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Electrochemotherapy; Humans; Male; Neoplasm Recurrence, Local; Rectal Neoplasms | 2020 |
Neoadjuvant volumetric modulated arc radiochemotherapy with a simultaneous integrated boost technique compared to standard chemoradiation for locally advanced rectal cancer
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy, Intensity-Modulated; Rectal Neoplasms | 2019 |
Total neoadjuvant treatment of locally advanced rectal cancer with high risk factors in Slovenia.
Topics: Adult; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Prospective Studies; Rectal Neoplasms; Risk Factors; Slovenia; Survival Rate; Treatment Outcome | 2019 |
Results of Tri-Modality Therapy for Rectal Cancer in Elderly Patients.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Humans; Karnofsky Performance Status; Male; Neoplasm Grading; Neoplasm Staging; Oxaliplatin; Postoperative Complications; Rectal Neoplasms; Retrospective Studies; Sex Factors; Treatment Outcome | 2019 |
Neoadjuvant chemotherapy without radiotherapy for patients with locally advanced rectal cancer. Oncologic outcomes.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Rectal Neoplasms | 2020 |
Treatment-resistant severe capecitabine-induced diarrhoea resolved with oral budesonide.
Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Budesonide; Capecitabine; Diarrhea; Female; Glucocorticoids; Humans; Rectal Neoplasms | 2019 |
Re-irradiation for recurrent rectal cancer - a single-center experience.
Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy, Adjuvant; Dose Fractionation, Radiation; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Norway; Pelvis; Proctectomy; Prospective Studies; Radiotherapy Dosage; Re-Irradiation; Rectal Neoplasms; Rectum; Treatment Outcome; Tumor Burden | 2020 |
FOLFOX and capecitabine-induced hepatic granuloma mimicking metastasis in a rectal cancer patient.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Fluorouracil; Granuloma; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Rectal Neoplasms | 2020 |
Improved Outcomes for Responders After Treatment with Induction Chemotherapy and Chemo(re)irradiation for Locally Recurrent Rectal Cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Female; Fluorouracil; Humans; Induction Chemotherapy; Leucovorin; Male; Margins of Excision; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Proctectomy; Rectal Neoplasms; Reoperation; Retrospective Studies; Survival Analysis; Treatment Outcome | 2020 |
Transcatheter rectal arterial chemoembolization with oxaliplatin plus S-1 concurrent chemoradiotherapy can improve the pathological remission rate in locally advanced rectal cancer: a comparative study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Colorectal Surgery; Dose Fractionation, Radiation; Drug Combinations; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Oxonic Acid; Prospective Studies; Rectal Neoplasms; Tegafur; Treatment Outcome; Young Adult | 2020 |
[Long-Term Survival of a Patient with Advanced Recurrent Rectal Cancer Treated with a Multidisciplinary Therapy including Five Operations-A Case Report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Female; Fluorouracil; Humans; Neoplasm Recurrence, Local; Rectal Neoplasms | 2020 |
[Long-Term Survival of a Patient with Metastatic Ovarian Cancer and Local Recurrence of Rectal Cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Female; Humans; Neoplasm Recurrence, Local; Ovarian Neoplasms; Rectal Neoplasms | 2020 |
MRI T2-weighted sequences-based texture analysis (TA) as a predictor of response to neoadjuvant chemo-radiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC).
Topics: Adult; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Treatment Outcome | 2020 |
Multi-modal radiomics model to predict treatment response to neoadjuvant chemotherapy for locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Capecitabine; Chemotherapy, Adjuvant; Female; Humans; Intestinal Mucosa; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Nomograms; Oxaliplatin; Predictive Value of Tests; Proctectomy; Rectal Neoplasms; Rectum; Reference Standards; Retrospective Studies; ROC Curve; Tomography, X-Ray Computed; Treatment Outcome | 2020 |
Pathological Predictors of Response to Neoadjuvant Treatment in Rectal Carcinoma.
Topics: Biopsy; Capecitabine; Chemoradiotherapy, Adjuvant; Dose Fractionation, Radiation; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Proctectomy; Prognosis; Rectal Neoplasms; Rectum; Treatment Outcome | 2021 |
Retrospective study of preoperative chemoradiotherapy with capecitabine versus capecitabine plus oxaliplatin for locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoplasm Staging; Oxaliplatin; Postoperative Complications; Preoperative Care; Rectal Neoplasms; Retrospective Studies | 2020 |
Quality of life after rectal-preserving treatment of rectal cancer.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Defecation; Dyspareunia; Erectile Dysfunction; Fecal Incontinence; Female; Gastrointestinal Hemorrhage; Humans; Lower Urinary Tract Symptoms; Male; Neoadjuvant Therapy; Organ Sparing Treatments; Proctectomy; Quality of Life; Rectal Neoplasms; Sexual Dysfunction, Physiological; Watchful Waiting | 2020 |
Influence of tumor location on short- and long-term outcomes after laparoscopic surgery for rectal cancer: a propensity score matched cohort study.
Topics: Capecitabine; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Incidence; Laparoscopy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Operative Time; Postoperative Complications; Proctectomy; Prognosis; Propensity Score; Rectal Neoplasms; Rectum; Retrospective Studies | 2020 |
Real-world outcomes for neoadjuvant capecitabine versus infusional 5-fluorouracil in the treatment of locally advanced rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Australia; Capecitabine; Fluorouracil; Humans; Neoadjuvant Therapy; Rectal Neoplasms; Treatment Outcome | 2021 |
[Pathological Complete Response in Multiple Advanced Rectal Cancers with Neoadjuvant CapeOX plus BV Therapy-A Case Report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Humans; Male; Neoadjuvant Therapy; Rectal Neoplasms; Rectum | 2020 |
Prognostic Value of Pretreatment Serum CA199 in Patients with Locally Advanced Rectal Cancer Treated with CRT Followed by TME with Normal Pretreatment Carcinoembryonic Antigen Levels.
Topics: Adenocarcinoma; Aged; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Carcinoembryonic Antigen; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Proctectomy; Prognosis; Rectal Neoplasms; Retrospective Studies | 2021 |
Predictive factors associated with complete pathological response after neoadjuvant treatment for rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Digital Rectal Examination; Female; Humans; Lymph Nodes; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Rectum; Retrospective Studies; Survival Rate; Treatment Outcome; Tumor Burden | 2021 |
[Long-Term Recurrence-Free Survival in a Patient Who Received Chemotherapy for Multiple Metastases of Rectal Cancer Including the Lesser-Curvature Lymph Node Metastasis-A Case Report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Rectal Neoplasms | 2020 |
Locally advanced rectal adenocarcinoma: Treatment sequences, intensification, and rectal organ preservation.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoembryonic Antigen; Chemoradiotherapy; Fluorouracil; Humans; Induction Chemotherapy; Leucovorin; Magnetic Resonance Imaging; Male; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Neoplasm, Residual; Organ Sparing Treatments; Organoplatinum Compounds; Proctectomy; Rectal Neoplasms | 2021 |
Risk factors for sexual dysfunction after rectal cancer surgery in 948 consecutive patients: A prospective cohort study.
Topics: Adenocarcinoma; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Leucovorin; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Proctectomy; Prospective Studies; Radiotherapy; Rectal Neoplasms; Risk Factors; Sexual Dysfunction, Physiological | 2021 |
Prognostic impact of additive chemotherapy after curative resection of metachronous colorectal liver metastasis: a single-centre retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colonic Neoplasms; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Humans; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Prognosis; Proportional Hazards Models; Rectal Neoplasms; Retrospective Studies; Risk Factors; Survival Rate; Time Factors | 2021 |
Improved response rate in patients with prognostically poor locally advanced rectal cancer after treatment with induction chemotherapy and chemoradiotherapy when compared with chemoradiotherapy alone: A matched case-control study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Case-Control Studies; Dose Fractionation, Radiation; Fascia; Female; Fluorouracil; Humans; Induction Chemotherapy; Leucovorin; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Rectal Neoplasms; Response Evaluation Criteria in Solid Tumors; Retrospective Studies; Treatment Outcome; Tumor Burden; Watchful Waiting | 2021 |
Neoadjuvant Capecitabine and Oxaliplatin Before Concurrent Capecitabine and Radiation in Locally Advanced Rectal Cancers: Experience of a Cancer Hospital in Pakistan.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cancer Care Facilities; Capecitabine; Humans; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Pakistan; Rectal Neoplasms; Retrospective Studies; Treatment Outcome; Young Adult | 2021 |
Concomitant Use of Proton Pump Inhibitors With Capecitabine Based Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: Is it Safe?
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Proton Pump Inhibitors; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2021 |
Tumor Volume as Predictor of Pathologic Complete Response Following Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies; Treatment Outcome; Tumor Burden | 2021 |
Relation between body composition and severe diarrhea in patients treated with preoperative chemoradiation with capecitabine for rectal cancer: a single-centre cohort study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Composition; Capecitabine; Cohort Studies; Deoxycytidine; Diarrhea; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2021 |
Neoadjuvant capecitabine in rectal cancer chemoradiotherapy: too early to ring the alarms.
Topics: Capecitabine; Chemoradiotherapy; Humans; Neoadjuvant Therapy; Rectal Neoplasms | 2021 |
Adherence to capecitabine in preoperative treatment of stage II and III rectal cancer: do we need to worry?
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Female; Humans; Male; Medication Adherence; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prospective Studies; Rectal Neoplasms; Spain | 2017 |
Serial renography for evaluation of the impact of capecitabine therapy on renal function: A case report.
Topics: Adult; Aftercare; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Signet Ring Cell; Drug Monitoring; Female; Humans; Kidney; Lymphatic Metastasis; Radioisotope Renography; Rectal Neoplasms | 2017 |
Continuous Effect of Radial Resection Margin on Recurrence and Survival in Rectal Cancer Patients Who Receive Preoperative Chemoradiation and Curative Surgery: A Multicenter Retrospective Analysis.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Incidence; Kaplan-Meier Estimate; Male; Margins of Excision; Middle Aged; Neoplasm Recurrence, Local; Rectal Neoplasms; Rectum; Republic of Korea; Retrospective Studies; Risk | 2017 |
Capecitabine-induced hyperglycemia without hyperlipidemia: a case report.
Topics: Adult; Antimetabolites, Antineoplastic; Capecitabine; Humans; Hyperglycemia; Male; Rectal Neoplasms; Sigmoid Neoplasms | 2017 |
Preoperative intensity-modulated radiotherapy with a simultaneous integrated boost combined with Capecitabine in locally advanced rectal cancer: short-term results of a multicentric study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies | 2017 |
[A Case of Alcoholic Liver Disease Presenting as Prominent Accumulation of Ascites Associated with Liver Damage Due to CapeOX].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Capecitabine; Chemoradiotherapy; Humans; Liver Diseases, Alcoholic; Male; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2017 |
Comparing pathological complete response rate using oral capecitabine versus infusional 5-fluorouracil with preoperative radiotherapy in rectal cancer treatment.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Chemoradiotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Retrospective Studies | 2018 |
Outcomes of patients with abdominoperineal resection (APR) and low anterior resection (LAR) who had very low rectal cancer.
Topics: Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Digestive System Surgical Procedures; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Perineum; Rectal Neoplasms; Rectum; Remission Induction; Retrospective Studies; Treatment Outcome | 2017 |
Outcome of neoadjuvant chemoradiation in MRI staged locally advanced rectal cancer: Retrospective analysis of 123 Chinese patients.
Topics: Adenocarcinoma; Adult; Aged; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Staging; Pelvis; Rectal Neoplasms; Rectum; Retrospective Studies; Survival Analysis; Treatment Outcome | 2018 |
Effect of Neoadjuvant Chemoradiation Therapy on Proteasome Pool in Rectal Cancer.
Topics: Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cysteine Endopeptidases; Gamma Rays; Gene Expression; Humans; Neoadjuvant Therapy; Proteasome Endopeptidase Complex; Rectal Neoplasms | 2017 |
[A Case of Recurrent Colon Cancer Successfully Treated with Capecitabine plus Bevacizumab].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Female; Humans; Rectal Neoplasms; Recurrence; Treatment Outcome | 2017 |
[A Case of Phrenic Nerve Paralysis During Adjuvant Chemotherapy for Rectal Cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colectomy; Humans; Male; Organoplatinum Compounds; Oxaliplatin; Paralysis; Peripheral Nervous System Diseases; Phrenic Nerve; Rectal Neoplasms | 2017 |
[Adjuvant Chemotherapy for Hemophilia B - A Case Report].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Hemophilia B; Humans; Male; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2017 |
Associations of Genetic Variations in MicroRNA Seed Regions With Acute Adverse Events and Survival in Patients With Rectal Cancer Receiving Postoperative Chemoradiation Therapy.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Dermatitis; Diarrhea; Disease-Free Survival; Female; Genetic Variation; Genotype; Humans; Kaplan-Meier Estimate; Leukopenia; Male; MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; Postoperative Care; Rectal Neoplasms | 2018 |
Pattern and Management of Recurrence of Mid-Low Rectal Cancer After Neoadjuvant Intensity-Modulated Radiotherapy: Single-Center Results of 687 Cases.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies; Young Adult | 2018 |
Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Ileostomy; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Micrometastasis; Organoplatinum Compounds; Oxaliplatin; Postoperative Care; Preoperative Care; Proctectomy; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Remission Induction; Retrospective Studies | 2018 |
Effect of Comorbidities in Stage II/III Colorectal Cancer Patients Treated With Surgery and Neoadjuvant/Adjuvant Chemotherapy: A Single-Center, Observational Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Colon; Colonic Neoplasms; Comorbidity; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Progression-Free Survival; Rectal Neoplasms; Rectum; Retrospective Studies | 2018 |
Comparison of pathological complete response rates after neoadjuvant short-course radiotherapy or chemoradiation followed by delayed surgery in locally advanced rectal cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Digestive System Surgical Procedures; Female; Humans; Logistic Models; Lymph Nodes; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Staging; Netherlands; Radiotherapy; Rectal Neoplasms; Rectum; Registries; Retrospective Studies; Time Factors; Treatment Outcome | 2018 |
[A Case of Colon Cancer with Brain, Liver and Lung Metastasis Successfully Treated with Bevacizumab plus Xelox Therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Oxaloacetates; Rectal Neoplasms | 2018 |
Tolerability, Safety, and Outcomes of Neoadjuvant Chemoradiotherapy With Capecitabine for Patients Aged ≥ 70 Years With Locally Advanced Rectal Cancer.
Topics: Adenocarcinoma; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Diarrhea; Disease-Free Survival; Fatigue; Female; Humans; Male; Neoadjuvant Therapy; Neoplasm Staging; Netherlands; Postoperative Complications; Proctectomy; Radiodermatitis; Rectal Neoplasms; Rectum; Retrospective Studies; Survival Rate | 2018 |
[Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy].
Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; DNA Mismatch Repair; Genetic Variation; Genotype; Haplotypes; Humans; MutL Protein Homolog 1; MutL Proteins; MutS Homolog 2 Protein; Neoadjuvant Therapy; Odds Ratio; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Rectal Neoplasms | 2018 |
[Research progress of neoadjuvant therapy for locally advanced rectal cancer].
Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Fluorouracil; Humans; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Treatment Outcome | 2018 |
Predictive Significance of Mucinous Histology on Pathologic Complete Response Rate Following Capecitabine-Based Neoadjuvant Chemoradiation in Rectal Cancer: a Comparative Study.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Drug Resistance, Neoplasm; Female; Humans; Male; Microsatellite Instability; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Predictive Value of Tests; Proctectomy; Prognosis; Progression-Free Survival; Radiation Tolerance; Rectal Neoplasms; Rectum; Retrospective Studies | 2019 |
[A Case of Postoperative Recurrence of Rectal Cancer in Which Desensitization Therapy Was Effective against Oxaliplatin Allergy in L-OHP].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Male; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Recurrence | 2018 |
Gender-differences of in vitro colonic motility after chemo- and radiotherapy in humans.
Topics: Aged; Antineoplastic Agents; Capecitabine; Colon; Electric Stimulation; Female; Gastrointestinal Motility; Humans; In Vitro Techniques; Male; Rectal Neoplasms; Sex Characteristics | 2018 |
Adjuvant Chemotherapy in Rectal Cancer Patients Treated With Preoperative Chemoradiation and Total Mesorectal Excision: A Multicenter and Retrospective Propensity-Score Matching Study.
Topics: Aged; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Oxaliplatin; Propensity Score; Rectal Neoplasms; Recurrence; Retrospective Studies; Treatment Outcome | 2019 |
C-Reactive Protein Level Predicts Survival Outcomes in Rectal Cancer Patients Undergoing Total Mesorectal Excision After Preoperative Chemoradiation Therapy.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; C-Reactive Protein; Capecitabine; Chemoradiotherapy, Adjuvant; Digestive System Surgical Procedures; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Preoperative Period; Radiotherapy Dosage; Rectal Neoplasms; Survival Rate | 2018 |
Planned organ preservation for early T2-3 rectal adenocarcinoma: A French, multicentre study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Brachytherapy; Capecitabine; Chemoradiotherapy; Female; France; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organ Sparing Treatments; Proctectomy; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies; Survival Rate; Tumor Burden | 2019 |
Rechallenge capecitabine after fluoropyrimidine-induced cardiotoxicity in rectal cancer: A case report.
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Capecitabine; Cardiotoxicity; Combined Modality Therapy; Female; Fluorouracil; Humans; Liver Neoplasms; Rectal Neoplasms | 2019 |
[A Case of Complete Response to Lower Rectal Cancer after Preoperative Chemotherapy with CapeOX Therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Fluorouracil; Humans; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Rectal Neoplasms; Remission Induction | 2018 |
Pathological complete response may underestimate distant metastasis in locally advanced rectal cancer following neoadjuvant chemoradiotherapy and radical surgery: Incidence, metastatic pattern, and risk factors.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluorouracil; Humans; Incidence; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Mesentery; Middle Aged; Mucin-1; Mucins; Neoadjuvant Therapy; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Proctectomy; Proportional Hazards Models; Rectal Neoplasms; Remission Induction; Retrospective Studies; Splenic Neoplasms | 2019 |
Quantitative analysis of 18-FDG-PET/MRI to assess pathological complete response following neoadjuvant radiochemotherapy in locally advanced rectal cancer. A prospective preliminary study.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Capecitabine; Chemoradiotherapy, Adjuvant; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Dosage; Rectal Neoplasms; ROC Curve | 2019 |
[Neoadjuvant, adjuvant and palliative systemic therapy of colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Humans; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms | 2018 |
Pretreatment blood biomarkers predict pathologic responses to neo-CRT in patients with locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Carcinoembryonic Antigen; Chemoradiotherapy; Female; Fluorouracil; Follow-Up Studies; GPI-Linked Proteins; Humans; Leucovorin; Lymphocytes; Male; Middle Aged; Neoadjuvant Therapy; Neutrophils; Oxaliplatin; Prognosis; Rectal Neoplasms; Retrospective Studies; ROC Curve; Survival Rate; Young Adult | 2019 |
Prognosis factors for recurrence in patients with locally advanced rectal cancer preoperatively treated with chemoradiotherapy and adjuvant chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Carcinoma; Chemoradiotherapy; Chemotherapy, Adjuvant; Cohort Studies; Deoxycytidine; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Rectal Neoplasms; Retrospective Studies; Risk Factors | 2013 |
Novel single-nucleotide polymorphism markers predictive of pathologic response to preoperative chemoradiation therapy in rectal cancer patients.
Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Capecitabine; Cell Line, Tumor; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Genetic Markers; Genome-Wide Association Study; Genotyping Techniques; Humans; Leucovorin; Male; Microfilament Proteins; Middle Aged; Preoperative Care; Radiation Tolerance; Rectal Neoplasms | 2013 |
Modern multidisciplinary treatment of rectal cancer based on staging with magnetic resonance imaging leads to excellent local control, but distant control remains a challenge.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms; Remission Induction; Treatment Outcome | 2013 |
Evolving role of neoadjuvant therapy in rectal cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Leucovorin; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Rectal Neoplasms | 2013 |
Therapy-related acute promyelocytic leukemia after chemoradiotherapy with capecitabine for rectal adenocarcinoma.
Topics: Antimetabolites, Antineoplastic; Bone Marrow; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasms, Second Primary; Rectal Neoplasms | 2014 |
[A case of necrotizing fasciitis developed in a patient with recurrent rectal cancer treated with chemotherapy].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fasciitis, Necrotizing; Fatal Outcome; Female; Fluorouracil; Humans; Middle Aged; Oxaloacetates; Rectal Neoplasms; Recurrence | 2013 |
Clinical outcome of neoadjuvant chemoradiation therapy with oxaliplatin and capecitabine or 5-fluorouracil for locally advanced rectal cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaloacetates; Rectal Neoplasms; Treatment Outcome | 2013 |
Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; GTP Phosphohydrolases; Humans; Male; Membrane Proteins; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Proto-Oncogene Proteins B-raf; Rectal Neoplasms; Retrospective Studies; Survival Rate; Tumor Suppressor Protein p53; Young Adult | 2014 |
Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications.
Topics: Adenocarcinoma; Aged; Anastomotic Leak; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Male; Matched-Pair Analysis; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum; Retrospective Studies; Surgical Wound Infection; Treatment Outcome | 2013 |
Comparison of two preoperative chemoradiotherapy regimens for locally advanced rectal cancer: capecitabine alone versus capecitabine plus irinotecan.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Postoperative Period; Preoperative Period; Rectal Neoplasms; Retrospective Studies; Time Factors; Treatment Outcome | 2013 |
Evaluation of capecitabine and oxaliplatin administered prior to and then concomitant to radiotherapy in high risk locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; China; Databases, Factual; Deoxycytidine; Diarrhea; Digestive System Surgical Procedures; Drug Administration Schedule; Female; Fluorouracil; Humans; Induction Chemotherapy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Proctitis; Radiodermatitis; Rectal Neoplasms; Remission Induction; Severity of Illness Index; Thrombocytopenia; Treatment Outcome | 2014 |
[Efficacy and safety of bevacizumab (BEV) plus chemotherapeutic agents in the treatment of metastatic colorectal cancer, mCRC].
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Hemorrhage; Humans; Hypertension; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Proteinuria; Rectal Neoplasms; Remission Induction; Young Adult | 2013 |
[Value of postoperative adjuvant chemotherapy in locally advanced rectal cancer patients with ypT1-4N0 after neo-adjuvant chemoradiotherapy].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Postoperative Period; Radiotherapy, Conformal; Rectal Neoplasms; Retrospective Studies; Survival Rate; Young Adult | 2013 |
[A case of metastatic colorectal cancer with hyperammonemic encephalopathy induced by 5-FU in a patient continuously treated with XELOX therapy].
Topics: Amino Acids, Branched-Chain; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases, Metabolic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Hyperammonemia; Liver Neoplasms; Male; Oxaloacetates; Rectal Neoplasms | 2013 |
[Neoadjuvant chemoradiotherapy with capecitabine and oxaliplatin for the treatment of locally advanced lower rectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Oxaloacetates; Rectal Neoplasms | 2013 |
Oxaliplatin and capecitabine concomitant with neoadjuvant radiotherapy and extended to the resting period in high risk locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; China; Combined Modality Therapy; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxaloacetates; Rectal Neoplasms | 2014 |
A clinical study of metastasized rectal cancer treatment: assessing a multimodal approach.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Rectal Neoplasms; Survival Rate | 2014 |
MRI and FDG-PET for assessment of response to neoadjuvant chemotherapy in locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Leucovorin; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaloacetates; Positron-Emission Tomography; Radiopharmaceuticals; Rectal Neoplasms; Retrospective Studies; ROC Curve; Treatment Outcome | 2014 |
Over compliance with capecitabine oral chemotherapy.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Male; Medication Adherence; Middle Aged; Rectal Neoplasms | 2014 |
Neoadjuvant capecitabine and oxaliplatin (XELOX) combined with bevacizumab for high-risk localized rectal cancer.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2014 |
[Concomitant use of romiplostim and chemotherapy for advanced rectal cancer associated with idiopathic thrombocytopenic purpura].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Purpura, Thrombocytopenic, Idiopathic; Receptors, Fc; Recombinant Fusion Proteins; Rectal Neoplasms; Thrombopoietin | 2014 |
Preoperative chemoradiotherapy in rectal cancer induces changes in the expression of nuclear β-catenin: prognostic significance.
Topics: Antimetabolites, Antineoplastic; beta Catenin; Cadherins; Capecitabine; Chemoradiotherapy; Colorectal Surgery; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Preoperative Care; Prospective Studies; Rectal Neoplasms; Treatment Outcome | 2014 |
[Feasibility study on Xelox (capecitabine plus oxapliplatin) in the volumetric modulated arc therapy (VMAT)-based preoperative chemoradiotherapy for locally advanced rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Feasibility Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2014 |
Gastrointestinal: bevacizumab-induced reversible posterior leukoencephalopathy syndrome in patient with rectal cancer.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Deoxycytidine; Drug Substitution; Fluorouracil; Humans; Leukoencephalopathies; Male; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Syndrome | 2014 |
The effects of neoadjuvant chemoradiotherapy on physical fitness and morbidity in rectal cancer surgery patients.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Cohort Studies; Deoxycytidine; Exercise Test; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxygen Consumption; Physical Fitness; Postoperative Complications; Prospective Studies; Rectal Neoplasms; Rectum; ROC Curve | 2014 |
Neoadjuvant chemoradiation with concomitant boost radiotherapy associated to capecitabine in rectal cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Rectal Neoplasms; Rectum; Survival Analysis | 2014 |
[A case of advanced rectal cancer that showed complete response to the addition of XELOX+bevacizumab therapy to preoperative chemoradiotherapy with S-1/CPT-11].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Neoplasm Staging; Oxaloacetates; Oxonic Acid; Rectal Neoplasms; Tegafur | 2014 |
[The combination of neoadjuvant chemoradiotherapy and epidermal growth factor receptor inhibitors in the treatment of rectal adenocarcinoma].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; ErbB Receptors; Fluorouracil; Humans; Neoadjuvant Therapy; Radiation Tolerance; Rectal Neoplasms | 2014 |
Prognostic factors for postoperative morbidity and tumour response after neoadjuvant chemoradiation followed by resection for rectal cancer.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Anastomotic Leak; Antimetabolites, Antineoplastic; Blood Transfusion; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Complications; Prognosis; Radiotherapy, Conformal; Rectal Neoplasms; Reoperation; Retrospective Studies; Surgical Wound Dehiscence; Surgical Wound Infection; Treatment Outcome | 2014 |
Helical tomotherapy combined with capecitabine in the preoperative treatment of locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Preoperative Care; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2014 |
Risk factors for bowel dysfunction after sphincter-preserving rectal cancer surgery: a prospective study using the Memorial Sloan Kettering Cancer Center bowel function instrument.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fecal Incontinence; Female; Fluorouracil; Humans; Ileostomy; Irinotecan; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Prospective Studies; Rectal Neoplasms; Risk Factors; Surveys and Questionnaires; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Fat composition changes in bone marrow during chemotherapy and radiation therapy.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Capecitabine; Cervical Vertebrae; Cetuximab; Chemoradiotherapy; Cisplatin; Deoxycytidine; Endometrial Neoplasms; Female; Fluorouracil; Humans; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Mitomycin; Paclitaxel; Prospective Studies; Prostatic Neoplasms; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Spine; Thoracic Vertebrae; Uterine Cervical Neoplasms | 2014 |
Tumour regression grading after chemoradiotherapy for locally advanced rectal cancer: a near pathologic complete response does not translate into good clinical outcome.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Lymph Nodes; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Neoplasm, Residual; Preoperative Care; Proportional Hazards Models; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Rectum; Remission Induction; Retrospective Studies; Survival Rate | 2014 |
EGFR ligands and DNA repair genes: genomic predictors of complete response after capecitabine-based chemoradiotherapy in locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Cohort Studies; Deoxycytidine; DNA Repair; ErbB Receptors; Female; Fluorouracil; Follow-Up Studies; Genetic Testing; Genomics; Humans; Ligands; Male; Middle Aged; Rectal Neoplasms; Treatment Outcome | 2015 |
Adjuvant treatment for locally advanced rectal cancer patients after preoperative chemoradiotherapy: when, and for whom?
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Rectal Neoplasms; Retrospective Studies; Survival Rate | 2014 |
S-1-Based versus capecitabine-based preoperative chemoradiotherapy in the treatment of locally advanced rectal cancer: a matched-pair analysis.
Topics: Capecitabine; Chemoradiotherapy; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Male; Matched-Pair Analysis; Middle Aged; Neoplasm Staging; Oxonic Acid; Postoperative Care; Preoperative Care; Rectal Neoplasms; Tegafur; Treatment Outcome | 2014 |
Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asia; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Drug Combinations; ErbB Receptors; Fluorouracil; Guideline Adherence; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Magnetic Resonance Imaging; Metastasectomy; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Oxonic Acid; Panitumumab; Practice Guidelines as Topic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Tegafur; Tomography, X-Ray Computed | 2014 |
Intussusception due to rectal adenocarcinoma in a young adult: a case report.
Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Capecitabine; Cell Differentiation; Chemotherapy, Adjuvant; Colonoscopy; Deoxycytidine; Fluorouracil; Humans; Immunohistochemistry; Intussusception; Magnetic Resonance Imaging; Male; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Rectal Neoplasms; Treatment Outcome; Young Adult | 2014 |
Clinical and dosimetric predictors of acute hematologic toxicity in rectal cancer patients undergoing chemoradiotherapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Femur; Fluorouracil; Hematologic Diseases; Humans; Leukocyte Count; Male; Middle Aged; Pelvic Bones; Platelet Count; Radiometry; Radiotherapy Dosage; Radiotherapy, Conformal; Rectal Neoplasms; Regression Analysis; Retrospective Studies; Sacrum | 2014 |
Role of genetic polymorphisms in NFKB-mediated inflammatory pathways in response to primary chemoradiation therapy for rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Cyclooxygenase 1; Cyclooxygenase 2; Deoxycytidine; Enteritis; Female; Fluorouracil; Humans; Inflammation; Interleukin-1beta; Male; Middle Aged; NF-kappa B; Organoplatinum Compounds; Polymorphism, Genetic; Proctitis; Pyridines; Radiation Tolerance; Radiotherapy, Conformal; Rectal Neoplasms; Retrospective Studies; Young Adult | 2014 |
IQGAP1 in rectal adenocarcinomas: localization and protein expression before and after radiochemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Immunoenzyme Techniques; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; ras GTPase-Activating Proteins; Rectal Neoplasms; Young Adult | 2015 |
[Influence of preoperative chemoradiotherapy on changes of epidermal growth factor receptor expression in patients treated by preoperative chemoradiotherapy for local advanced rectal carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; ErbB Receptors; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Preoperative Care; Prognosis; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies | 2014 |
Complete Neoadjuvant Treatment for Rectal Cancer: The Brown University Oncology Group CONTRE Study.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Digestive System Surgical Procedures; Drug Administration Schedule; Female; Fluorouracil; Humans; Induction Chemotherapy; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2017 |
Gemcitabine plus capecitabine (Gem-Cape) biweekly in chemorefractory metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Capecitabine; Colonic Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Peritoneal Neoplasms; Rectal Neoplasms; Retreatment; Retrospective Studies; Survival Rate | 2015 |
Association between the cytogenetic profile of tumor cells and response to preoperative radiochemotherapy in locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Chromosome Aberrations; Clonal Evolution; Cohort Studies; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; In Situ Hybridization, Fluorescence; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Treatment Outcome | 2014 |
Efficacy and safety of neoadjuvant intensity-modulated radiotherapy with concurrent capecitabine for locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Complications; Radiation Injuries; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Rectum; Retrospective Studies; Treatment Outcome; Tumor Burden; Young Adult | 2015 |
Observational study of adjuvant therapy with capecitabine in colon cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Rectal Neoplasms; Retrospective Studies | 2015 |
[Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer].
Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fluorouracil; Humans; Ileus; Male; Neoplasm Staging; Rectal Neoplasms | 2014 |
[A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Laparoscopy; Lymph Node Excision; Male; Neoadjuvant Therapy; Neoplasm Staging; Oxaloacetates; Rectal Neoplasms | 2014 |
[A case of rectal cancer with brain metastasis successfully treated with combined modality therapy - a case report].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Oxaloacetates; Rectal Neoplasms; Treatment Outcome | 2014 |
[A case of metastatic rectal cancer with fulminant hepatitis caused by XELOX therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Hepatitis; Humans; Male; Neoplasm Metastasis; Oxaloacetates; Rectal Neoplasms | 2014 |
[Preoperative chemoradiotherapy for rectal cancer: experience from one centre].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2015 |
Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Cystitis; Diarrhea; DNA-Binding Proteins; Female; Fluorouracil; Gastrointestinal Hemorrhage; Genotype; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Pelvic Pain; Polymorphism, Single Nucleotide; Proctitis; Rad51 Recombinase; Radiation Injuries; Radiodermatitis; Radiotherapy, Conformal; Rectal Neoplasms; X-ray Repair Cross Complementing Protein 1 | 2017 |
[The present status of CapeOX as adjuvant chemotherapy for colorectal cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colonic Neoplasms; Deoxycytidine; Female; Fluorouracil; Hand-Foot Syndrome; Humans; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies | 2015 |
YKL-40/c-Met expression in rectal cancer biopsies predicts tumor regression following neoadjuvant chemoradiotherapy: a multi-institutional study.
Topics: Adenocarcinoma; Adipokines; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy; Capecitabine; Chemoradiotherapy, Adjuvant; Chitinase-3-Like Protein 1; Drug Resistance, Neoplasm; Female; Gamma Rays; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Lectins; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins c-met; Rectal Neoplasms | 2015 |
Postoperative Capecitabine with Concurrent Intensity-Modulated Radiotherapy or Three-Dimensional Conformal Radiotherapy for Patients with Stage II and III Rectal Cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Dose Fractionation, Radiation; Female; Humans; Male; Middle Aged; Postoperative Care; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies; Survival Analysis; Treatment Outcome | 2015 |
Role of Adjuvant Chemotherapy in ypT0-2N0 Patients Treated with Preoperative Chemoradiation Therapy and Radical Resection for Rectal Cancer.
Topics: Adenocarcinoma; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Confidence Intervals; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Organ Sparing Treatments; Preoperative Care; Propensity Score; Radiotherapy Dosage; Rectal Neoplasms; Regression Analysis; Treatment Outcome | 2015 |
Comparison of oncologic outcomes of metastatic rectal cancer patients with or without neoadjuvant chemoradiotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Rectal Neoplasms; Survival Rate; Treatment Outcome | 2015 |
[A Case of Concurrent Cancer in a Giant Rectal Villous Adenoma That Resulted in Extensive Lymph Node Metastases].
Topics: Adenoma, Villous; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Oxaloacetates; Rectal Neoplasms; Recurrence | 2015 |
Clinical outcomes of elderly patients receiving neoadjuvant chemoradiation for locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Quinazolines; Rectal Neoplasms; Retrospective Studies; Survival Rate; Thiophenes; Young Adult | 2015 |
Chemoradiation for High-grade Neuroendocrine Carcinoma of the Rectum and Anal Canal.
Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Camptothecin; Capecitabine; Carboplatin; Carcinoma, Neuroendocrine; Chemoradiotherapy; Cisplatin; Consolidation Chemotherapy; Diarrhea; Digestive System Surgical Procedures; Disease-Free Survival; Etoposide; Female; Fluorouracil; Humans; Induction Chemotherapy; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Pelvis; Radiation Injuries; Radiodermatitis; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Rectum; Retrospective Studies; Survival Rate; Tumor Burden | 2017 |
Can dosimetric parameters predict acute hematologic toxicity in rectal cancer patients treated with intensity-modulated pelvic radiotherapy?
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Bone Marrow; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Female; Hematologic Diseases; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organs at Risk; Pelvis; Prognosis; Radiometry; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Severity of Illness Index; Sex Factors | 2015 |
Use of the new Da Vinci Xi during robotic rectal resection for cancer: technical considerations and early experience.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Blood Loss, Surgical; Capecitabine; Chemoradiotherapy, Adjuvant; Clinical Competence; Equipment Design; Female; Humans; Learning Curve; Male; Middle Aged; Neoadjuvant Therapy; Operative Time; Patient Positioning; Rectal Neoplasms; Robotic Surgical Procedures | 2015 |
Prediction of neoadjuvant radiation chemotherapy response and survival using pretreatment [(18)F]FDG PET/CT scans in locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Disease-Free Survival; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Imaging, Three-Dimensional; Leucovorin; Male; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Positron-Emission Tomography; Prognosis; Proportional Hazards Models; Radiopharmaceuticals; Rectal Neoplasms; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome | 2016 |
Neoadjuvant Long-Course Chemoradiotherapy for Rectal Cancer: Does Time to Surgery Matter?
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Prospective Studies; Rectal Neoplasms; Time Factors; Treatment Outcome | 2015 |
Forbidden to Drive - a New Chemotherapy Side Effect.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Humans; Male; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 2015 |
Further evidence for preoperative chemoradiotherapy and transanal endoscopic surgery (TEM) in T2-3s,N0,M0 rectal cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Prospective Studies; Rectal Neoplasms; Transanal Endoscopic Surgery; Treatment Outcome | 2016 |
Long Term Outcomes of Preoperative versus Postoperative Concurrent Chemoradiation for Locally Advanced Rectal Cancer: Experience from Ramathibodi Medical School in Thailand.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Postoperative Period; Preoperative Period; Prognosis; Rectal Neoplasms; Retrospective Studies; Schools, Medical; Survival Rate; Thailand; Time Factors | 2015 |
Thymidine phosphorylase and hypoxia-inducible factor 1-α expression in clinical stage II/III rectal cancer: association with response to neoadjuvant chemoradiation therapy and prognosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Chemoradiotherapy, Adjuvant; Disease Progression; Disease-Free Survival; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Rectal Neoplasms; Retrospective Studies; Risk Factors; Thymidine Phosphorylase; Time Factors; Treatment Outcome | 2015 |
Capecitabine-Induced Severe Toxicity Secondary to DPD Deficiency and Successful Treatment with Low Dose 5-Fluorouracil.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Dose-Response Relationship, Drug; Fluorouracil; Humans; Male; Middle Aged; Rectal Neoplasms | 2017 |
[Two Cases of Rectal Cancer Resected Curatively after Chemotherapy with CapeOX plus Bmab].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Humans; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2015 |
[A Patient with Rectal Cancer and Multiple Lung Metastases Treated with XELOX plus Bevacizumab (Bev) Therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colectomy; Deoxycytidine; Female; Fluorouracil; Humans; Lung Neoplasms; Oxaloacetates; Rectal Neoplasms; Treatment Outcome | 2015 |
[Super-Elderly Patient with Recurrent Rectal Cancer with Liver Metastases Effectively Treated with Capecitabine plus Bevacizumab Chemotherapy--Report of a Case].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Female; Humans; Liver Neoplasms; Rectal Neoplasms; Recurrence; Treatment Outcome | 2015 |
[A Case of Recurrence of Rectal Cancer with Para-Aortic Lymph Node Metastases Successfully Resected Resulting in Long Term Survival].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Aorta; Capecitabine; Chemotherapy, Adjuvant; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Rectal Neoplasms; Recurrence; Time Factors | 2015 |
Contact radiotherapy boost in association with 'watch and wait' for rectal cancer: initial experience and outcomes from a shared programme between a district general hospital network and a regional oncology centre.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Brachytherapy; Cancer Care Facilities; Capecitabine; Chemoradiotherapy; Female; Hospitals, District; Hospitals, General; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy; Rectal Neoplasms; Remission Induction; Retrospective Studies; Watchful Waiting | 2016 |
Comparative effectiveness of postoperative chemotherapy among older patients with non-metastatic rectal cancer treated with preoperative chemoradiotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Databases, Factual; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Medicare; Mortality; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Postoperative Care; Preoperative Care; Propensity Score; Proportional Hazards Models; Rectal Neoplasms; Rectum; SEER Program; Treatment Outcome; United States | 2016 |
Outcome Assessments and Cost Avoidance of an Oral Chemotherapy Management Clinic.
Topics: Administration, Oral; Ambulatory Care Facilities; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Cost Savings; Costs and Cost Analysis; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Male; Medication Errors; Middle Aged; Outcome Assessment, Health Care; Pancreatic Neoplasms; Patient Care; Patient Compliance; Patient Education as Topic; Rectal Neoplasms | 2016 |
Severe myositis of the hip flexors after pre-operative chemoradiation therapy for locally advanced rectal cancer: case report.
Topics: Aged; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Humans; Male; Myositis; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms | 2016 |
Sequential boost in neoadjuvant irradiation for T3N0-1 rectal cancer: long-term results from a single-center experience.
Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Digestive System Surgical Procedures; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Tract; Humans; Ileostomy; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organ Sparing Treatments; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Time Factors; Treatment Outcome; Urogenital System | 2016 |
Long-Term Bone Marrow Suppression During Postoperative Chemotherapy in Rectal Cancer Patients After Preoperative Chemoradiation Therapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Diseases; Capecitabine; Chemoradiotherapy; Female; Fluorouracil; Humans; Ilium; Leucovorin; Leukopenia; Logistic Models; Lumbar Vertebrae; Male; Middle Aged; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Pelvic Bones; Preoperative Care; Rectal Neoplasms; Retrospective Studies; ROC Curve; Sacrum; Statistics, Nonparametric; Thrombocytopenia | 2016 |
Oncologic Safety of Local Excision Compared With Total Mesorectal Excision for ypT0-T1 Rectal Cancer: A Propensity Score Analysis.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Digestive System Surgical Procedures; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Propensity Score; Rectal Neoplasms; Retrospective Studies; Survival Rate | 2016 |
[A Case of Unresectable Rectal Cancer with Multiple Liver Metastases Treated Effectively with 22 Courses of XELOX Therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Oxaloacetates; Rectal Neoplasms; Tomography, X-Ray Computed; Treatment Outcome | 2016 |
[Research hotspot and progress of preoperative chemoradiotherapy for rectal cancer].
Topics: Antineoplastic Agents; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Rectal Neoplasms | 2016 |
[Clinical study on locally advanced rectal cancer patients with pathological complete response after neoadjuvant chemoradiotherapy].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oxaloacetates; Rectal Neoplasms; Retrospective Studies; Treatment Outcome; Young Adult | 2016 |
[Expression of CD133 in rectal cancer tissues and its relationship with neoadjuvant chemoradiotherapy].
Topics: AC133 Antigen; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Rectal Neoplasms | 2016 |
Use of sequential endorectal US to predict the tumor response of preoperative chemoradiotherapy in rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Digestive System Surgical Procedures; Endosonography; Female; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Treatment Outcome | 2017 |
[Short-term efficacy comparison between preoperative three dimensional conformal radiotherapy and volumetric modulated arc therapy concurrently combined with chemotherapy in the treatment of locally advanced rectal carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectal Neoplasms; Retrospective Studies | 2016 |
Outcomes of Preoperative Chemoradiotherapy and Combined Chemotherapy with Radiotherapy Without Surgery for Locally Advanced Rectal Cancer.
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Preoperative Period; Radiotherapy Dosage; Rectal Neoplasms; Survival Rate; Treatment Outcome; Young Adult | 2016 |
Pre-operative chemoradiotherapy using capecitabine and cetuximab followed by definitive surgery in patients with operable rectal cancer.
Topics: Adult; Aged; Capecitabine; Cetuximab; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Survival Analysis; Treatment Outcome | 2016 |
Preoperative chemoradiotherapy for elderly patients with locally advanced rectal cancer-a real-world outcome study.
Topics: Age Factors; Aged; Aged, 80 and over; Capecitabine; Chemoradiotherapy; Diarrhea; Disease-Free Survival; Female; Fluorouracil; Humans; Lymphatic Metastasis; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Proportional Hazards Models; Radiation Dosage; Rectal Neoplasms; Retrospective Studies; Risk Factors; Treatment Outcome | 2016 |
[Comparison of the Cost-Effectiveness of the SOX and COX Regimens in Patients with Unresectable Advanced and Recurrent Colorectal Cancer Using a Clinical Decision Analysis Approach].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Cost-Benefit Analysis; Decision Support Techniques; Drug Combinations; Female; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Rectal Neoplasms; Recurrence; Tegafur | 2016 |
Role of pelvic radiotherapy for locally advanced rectal cancer and synchronous unresectable distant metastases.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Disease Progression; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pelvis; Prognosis; Proportional Hazards Models; Rectal Neoplasms; Retrospective Studies | 2016 |
A Comparative Effectiveness Study of Two Oral Chemotherapy Drugs (UFT vs. Capecitabine) in Neoadjuvant Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Female; Humans; Male; Rectal Neoplasms; Remission Induction; Survival Rate; Tegafur; Uracil | 2016 |
Management of rectal cancer: the 2016 French guidelines.
Topics: Adenocarcinoma; Anal Canal; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Colostomy; Digestive System Surgical Procedures; Fluorouracil; France; Humans; Laparoscopy; Liver Neoplasms; Lymph Node Excision; Metastasectomy; Neoadjuvant Therapy; Neoplasm Staging; Organ Sparing Treatments; Pelvis; Postoperative Complications; Radiotherapy, Adjuvant; Rectal Neoplasms; Rectum | 2017 |
Adjuvant treatment for resected rectal cancer: impact of standard and intensified postoperative chemotherapy on disease-free survival in patients undergoing preoperative chemoradiation-a propensity score-matched analysis of an observational database.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Databases, Factual; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Propensity Score; Rectal Neoplasms; Retrospective Studies; Young Adult | 2016 |
A Retrospective Analysis on Two-week Short-course Pre-operative Radiotherapy in Elderly Patients with Resectable Locally Advanced Rectal Cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Leucovorin; Male; Neoadjuvant Therapy; Organ Sparing Treatments; Organoplatinum Compounds; Oxaloacetates; Rectal Neoplasms; Retrospective Studies; Survival Analysis; Treatment Outcome | 2016 |
[Pathological Complete Response in a Case of Multiple Liver Metastases from Rectal Cancer Treated with XELOX plus Bevacizumab(Bev)Therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colectomy; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Hepatectomy; Humans; Liver Neoplasms; Middle Aged; Oxaloacetates; Rectal Neoplasms; Treatment Outcome | 2016 |
[A Case of Advanced Rectal Cancer Resulting in a Pathologically Complete Response after Neoadjuvant Chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Oxaloacetates; Rectal Neoplasms; Treatment Outcome | 2016 |
Patients with pathological stage N2 rectal cancer treated with early adjuvant chemotherapy have a lower treatment failure rate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Treatment Outcome; Young Adult | 2017 |
Combined cetuximab, capecitabine, oxaliplatin, and radiotherapy in rectal cancer: Dr. Jekyll or Mr. Hyde? In regard to Rödel et al. (Int J Radiat Oncol Biol Phys 2008;70:1081-1086.).
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Combined Modality Therapy; Deoxycytidine; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Radiotherapy; Rectal Neoplasms | 2008 |
Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; MicroRNAs; Middle Aged; Radiotherapy, Conformal; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2008 |
Use of molecular imaging to predict clinical outcome in patients with rectal cancer after preoperative chemotherapy and radiation.
Topics: Adenocarcinoma; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorodeoxyglucose F18; Fluorouracil; Humans; Mitomycin; Neoadjuvant Therapy; Positron-Emission Tomography; Radiopharmaceuticals; Rectal Neoplasms; Statistics, Nonparametric | 2009 |
Can an FDG-PET/CT predict tumor clearance of the mesorectal fascia after preoperative chemoradiation of locally advanced rectal cancer?
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fascia; Fasciotomy; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Image Enhancement; Image Processing, Computer-Assisted; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Positron-Emission Tomography; Rectal Neoplasms; Rectum; Software; Survival Rate; Tomography, X-Ray Computed | 2008 |
Regression of rectal cancer with radiotherapy with or without concurrent capecitabine--optimising the timing of surgical resection.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Radiotherapy, Conformal; Rectal Neoplasms | 2009 |
Caveolin-1 as a prognostic marker for local control after preoperative chemoradiation therapy in rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Caveolin 1; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Organoplatinum Compounds; Oxaliplatin; Prognosis; Protein Array Analysis; Rectal Neoplasms; Remission Induction; RNA, Messenger | 2009 |
To widen the setting of cancer patients who could benefit from metronomic capecitabine.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease Progression; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Rectal Neoplasms; Stomach Neoplasms; Treatment Outcome | 2009 |
Hyperfractionated accelerated radiotherapy for rectal cancer in patients with prior pelvic irradiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Organoplatinum Compounds; Pelvis; Pyridines; Radiation Injuries; Rectal Neoplasms; Retreatment; Retrospective Studies; Survival Rate; Tumor Burden | 2010 |
[Prognostic analysis of 443 cases of stage II colorectal cancer and the value of adjuvant chemotherapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Child; Colonic Neoplasms; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Intestinal Obstruction; Intestinal Perforation; Leucovorin; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaloacetates; Proportional Hazards Models; Rectal Neoplasms; Retrospective Studies; Survival Rate; Young Adult | 2009 |
[Clinical significance of a transient increase in carcinoembryonic antigen and carbohydrate antigen 19-9 in patients with metastatic colorectal cancer receiving chemotherapy].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Camptothecin; Capecitabine; Carcinoembryonic Antigen; Child; Colonic Neoplasms; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Rectal Neoplasms; Remission Induction; Young Adult | 2009 |
Thymidine phosphorylase to dihydropyrimidine dehydrogenase ratio as a predictive factor of response to preoperative chemoradiation with capecitabine in patients with advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Radiation Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms; Thymidine Phosphorylase; Treatment Outcome; Young Adult | 2010 |
Neoadjuvant chemoradiotherapy with capecitabine followed by laparoscopic resection in locally advanced tumors of middle and low rectum - toxicity and complications of the treatment.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Colectomy; Deoxycytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Follow-Up Studies; Humans; Laparoscopy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Postoperative Complications; Prodrugs; Prospective Studies; Rectal Neoplasms; Time Factors; Treatment Outcome | 2010 |
MGMT -535G>T polymorphism is associated with prognosis for patients with metastatic colorectal cancer treated with oxaliplatin-based chemotherapy.
Topics: Amino Acid Substitution; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chromosome Mapping; Colonic Neoplasms; Colorectal Neoplasms; Deoxycytidine; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Female; Fluorouracil; Genotype; Humans; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prognosis; Rectal Neoplasms; Tumor Suppressor Proteins | 2010 |
Complications after sphincter-saving resection in rectal cancer patients according to whether chemoradiotherapy is performed before or after surgery.
Topics: Adenocarcinoma; Adult; Aged; Anal Canal; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Drug Administration Schedule; Enteritis; Female; Fluorouracil; Humans; Ileostomy; Intestinal Obstruction; Korea; Leucovorin; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Postoperative Complications; Preoperative Care; Radiotherapy Dosage; Rectal Fistula; Rectal Neoplasms; Rectovaginal Fistula; Rectum; Urinary Bladder Fistula; Young Adult | 2010 |
Evaluation of early metabolic responses in rectal cancer during combined radiochemotherapy or radiotherapy alone: sequential FDG-PET-CT findings.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Image Interpretation, Computer-Assisted; Male; Neoplasm Staging; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms; Statistics, Nonparametric; Tomography, X-Ray Computed; Treatment Outcome | 2010 |
Neoadjuvant chemotherapy in MRI-staged rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2010 |
Capecitabine initially concomitant to radiotherapy then perioperatively administered in locally advanced rectal cancer. In regard to MG Zampino et al. (Int J Radiat Oncol Biol Phys 2009;75:421-427).
Topics: Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Postoperative Complications; Rectal Neoplasms; Remission Induction; Time Factors; Urogenital System | 2010 |
Preoperative chemoradiotherapy for rectal cancer: a comparison between intravenous 5-fluorouracil and oral capecitabine.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms; Remission Induction; Retrospective Studies; Survival Analysis; Young Adult | 2010 |
Development of bronchiolitis obliterans organizing pneumonia with platinum-based chemotherapy for metastatic rectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Cryptogenic Organizing Pneumonia; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2010 |
[Efficacy observation of accelerated hyperfractionation recourse radiotherapy plus concurrent capecitabine in the treatment of locoregional recurrent rectal cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dose Fractionation, Radiation; Fluorouracil; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Rectal Neoplasms; Treatment Outcome | 2010 |
Preoperative chemoradiation for rectal cancer using capecitabine and celecoxib correlated with posttreatment assessment of thymidylate synthase and thymidine phosphorylase expression.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Celecoxib; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Pyrazoles; Rectal Neoplasms; Sulfonamides; Survival Rate; Thymidine Phosphorylase; Thymidylate Synthase; Young Adult | 2011 |
Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Indoles; Least-Squares Analysis; Leucovorin; Male; Middle Aged; Neoplasm Proteins; Organoplatinum Compounds; Oxaliplatin; Phosphorylation; Phosphotransferases; Pyrroles; Radiation Tolerance; Rectal Neoplasms; Rectum; Remission Induction; Signal Transduction; Substrate Specificity; Sunitinib; Treatment Outcome | 2010 |
Radiosensitizing drugs: lessons to be learned from the oxaliplatin story.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome | 2010 |
Are we ready to use an early alternative end point as the primary end point of a phase III study in rectal cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Rectal Neoplasms; Treatment Outcome | 2010 |
Patterns of response after preoperative intensity-modulated radiation therapy and capecitabine/oxaliplatin in rectal cancer: is there still a place for ecoendoscopic ultrasound?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Endosonography; Female; Fluorouracil; Humans; Lymph Nodes; Male; Middle Aged; Neoplasm Staging; Oxaloacetates; Preoperative Care; Rectal Neoplasms; Sensitivity and Specificity; Treatment Outcome | 2011 |
Predictive factors of tumor response after neoadjuvant chemoradiation for locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Carcinoembryonic Antigen; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Staging; Rectal Neoplasms; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult | 2011 |
Standard-dose tegafur combined with uracil is not safe treatment after severe toxicity from 5-fluorouracil or capecitabine.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Prodrugs; Rectal Neoplasms; Tegafur | 2010 |
Laparoscopic proctectomy after neoadjuvant therapy: safety and long-term follow-up.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Laparoscopy; Male; Middle Aged; Neoadjuvant Therapy; Radiotherapy Dosage; Rectal Neoplasms; Rectum; Retrospective Studies; Treatment Outcome | 2011 |
Risk-adapted adjuvant chemotherapy after concomitant fluoropyrimidine-radiotherapy neoadjuvant treatment for patients with resectable cT3-4 or N+ rectal cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms | 2011 |
Toxicity and complications of preoperative chemoradiotherapy for locally advanced rectal cancer.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Care; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Rectal Neoplasms | 2011 |
5-FU-induced hyperammonemic encephalopathy in a case of metastatic rectal adenocarcinoid successfully rechallenged with the fluoropyrimidine analog, capecitabine.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Brain Diseases; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Hyperammonemia; Liver Neoplasms; Rectal Neoplasms; Treatment Outcome | 2011 |
Stage-to-stage comparison of preoperative and postoperative chemoradiotherapy for T3 mid or distal rectal cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Staging; Postoperative Period; Preoperative Period; Prognosis; Rectal Neoplasms; Retrospective Studies; Survival Rate; Time Factors | 2012 |
Mucinous rectal cancer: effectiveness of preoperative chemoradiotherapy and prognosis.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Male; Medical Records; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Preoperative Care; Prospective Studies; Radiotherapy; Rectal Neoplasms; Retrospective Studies; Survival Rate; Treatment Outcome | 2011 |
Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Female; Fluorouracil; Follow-Up Studies; Gamma Rays; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm, Residual; Organoplatinum Compounds; Oxaliplatin; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult | 2011 |
Accelerated hyperfractionation field-involved re-irradiation combined with concurrent capecitabine chemotherapy for locally recurrent and irresectable rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease Progression; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Karnofsky Performance Status; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Radiotherapy, Conformal; Rectal Neoplasms | 2012 |
[Ileitis following capecitabine use].
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Ileitis; Male; Rectal Neoplasms | 2011 |
MRI-based indications for neoadjuvant radiochemotherapy in rectal carcinoma: interim results of a prospective multicenter observational study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Preoperative Care; Prospective Studies; Rectal Neoplasms; Survival Rate; Treatment Outcome | 2011 |
Clinical significance of pre- to post-chemoradiotherapy s-CEA reduction ratio in rectal cancer patients treated with preoperative chemoradiotherapy and curative resection.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoembryonic Antigen; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Enzyme-Linked Immunosorbent Assay; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Rectal Neoplasms; Retrospective Studies; Survival Rate; Young Adult | 2011 |
Tumor volume reduction rate after preoperative chemoradiotherapy as a prognostic factor in locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Preoperative Care; Rectal Neoplasms; Retrospective Studies; Tumor Burden | 2012 |
[Eighty-five-year-old patient with recurrent rectal cancer effectively treated with CapeOX chemotherapy].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Recurrence; Tomography, X-Ray Computed | 2011 |
[A case of advanced rectal cancer resected successfully after preoperative XELOX chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Diagnosis, Differential; Female; Fluorouracil; Humans; Neoplasm Staging; Ovarian Neoplasms; Oxaloacetates; Rectal Neoplasms; Tomography, X-Ray Computed | 2011 |
A single-centre experience of chemoradiotherapy for rectal cancer: is there potential for nonoperative management?
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Rectal Neoplasms; Retrospective Studies; Time Factors | 2012 |
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Neoadjuvant Therapy; Predictive Value of Tests; Prognosis; Real-Time Polymerase Chain Reaction; Rectal Neoplasms; Statistics, Nonparametric; Transketolase; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
[A resected case of locally invasive rectal cancer successfully treated with neoadjuvant capecitabine, oxaliplatin, bevacizumab and radiation therapy].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Tomography, X-Ray Computed | 2011 |
Securin identifies a subgroup of patients with poor outcome in rectal cancer treated with long-course (chemo)radiotherapy.
Topics: Aged; Antimetabolites, Antineoplastic; Biopsy; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Proportional Hazards Models; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Neoplasms; Securin; Treatment Outcome | 2011 |
Safety and outcome of chemoradiotherapy in elderly patients with rectal cancer: results from two French tertiary centres.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; France; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Tegafur; Vitamin B Complex | 2012 |
A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Biopsy; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Male; Microarray Analysis; MicroRNAs; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Sensitivity and Specificity | 2012 |
A observational study of the efficacy and safety of capecitabine versus bolus infusional 5-fluorouracil in pre-operative chemoradiotherapy for locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Rectal Neoplasms; Treatment Outcome | 2012 |
Adjuvant chemotherapy with or without pelvic radiotherapy after simultaneous surgical resection of rectal cancer with liver metastases: analysis of prognosis and patterns of recurrence.
Topics: Adult; Aged; Analysis of Variance; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Pelvis; Postoperative Care; Probability; Prognosis; Rectal Neoplasms; Retrospective Studies; Selection Bias | 2012 |
Predicting pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer using 18FDG-PET/CT.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiopharmaceuticals; Rectal Neoplasms; Retrospective Studies; Risk Factors; Survival Rate; Tomography, X-Ray Computed | 2012 |
Simultaneous neoadjuvant radiochemotherapy with capecitabine and oxaliplatin for locally advanced rectal cancer. Treatment outcome outside clinical trials.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2012 |
Severe hypertriglyceridaemia associated with the use of capecitabine.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Hypertriglyceridemia; Male; Middle Aged; Rectal Neoplasms | 2012 |
MR imaging of rectal cancer before and after chemoradiation therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Image Interpretation, Computer-Assisted; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Radiotherapy Dosage; Radiotherapy, Conformal; Rectal Neoplasms; Treatment Outcome | 2012 |
Dose--volume effects on patient-reported acute gastrointestinal symptoms during chemoradiation therapy for rectal cancer.
Topics: Aged; Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Defecation; Deoxycytidine; Diarrhea; Female; Fluorouracil; Gastrointestinal Diseases; Humans; Intestine, Large; Intestine, Small; Male; Massachusetts; Middle Aged; Pain; Quality of Life; Rectal Neoplasms | 2012 |
Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before total mesorectal excision in patients with locally advanced rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2012 |
[A case of rectal hemorrhage during chemotherapy with bevacizumab for local recurrence of rectal cancer].
Topics: Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Deoxycytidine; Fluorouracil; Gastrointestinal Hemorrhage; Humans; Male; Oxaloacetates; Rectal Neoplasms; Recurrence | 2012 |
[A case of locally advanced rectal cancer had a pathological complete response to XELOX Therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoembryonic Antigen; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Oxaloacetates; Rectal Neoplasms | 2012 |
Hand-foot syndrome related to chemotherapy.
Topics: Antineoplastic Agents; Capecitabine; Deoxycytidine; Female; Fluorouracil; Hand-Foot Syndrome; Humans; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms | 2012 |
Capecitabine in the treatment of rectal cancer.
Topics: Antineoplastic Agents; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Rectal Neoplasms | 2012 |
[A case report of pathologically complete response of locally advanced rectal cancer after neoadjuvant chemoradiotherapy with XELOX and bevacizumab].
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Male; Neoadjuvant Therapy; Oxaloacetates; Rectal Neoplasms; Tomography, X-Ray Computed | 2012 |
[Increased INR from concomitant use of acenocoumarol and capecitabine].
Topics: Acenocoumarol; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; Atrial Fibrillation; Capecitabine; Deoxycytidine; Drug Interactions; Erythrocyte Transfusion; Female; Fluorouracil; Gastrointestinal Hemorrhage; Heparin, Low-Molecular-Weight; Humans; International Normalized Ratio; Rectal Neoplasms | 2012 |
Early prediction of histopathological response of rectal tumors after one week of preoperative radiochemotherapy using 18 F-FDG PET-CT imaging. A prospective clinical study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Preoperative Care; Prognosis; Prospective Studies; Radiopharmaceuticals; Radiotherapy Dosage; Rectal Neoplasms; Tegafur; Tomography, X-Ray Computed; Uracil | 2012 |
Is restaging with chest and abdominal CT scan after neoadjuvant chemoradiotherapy for locally advanced rectal cancer necessary?
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy, Adjuvant; Deoxycytidine; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiography, Abdominal; Radiography, Thoracic; Rectal Neoplasms; Rectum; Retrospective Studies; Tomography, X-Ray Computed | 2013 |
Oncologically safe distal resection margins in rectal cancer patients treated with chemoradiotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy, Adjuvant; Cross-Sectional Studies; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Rectum; Retrospective Studies; Survival Analysis; Treatment Outcome | 2012 |
Prognostic significance of thymidylate synthase polymorphisms in rectal cancer patients treated with neoadjuvant chemoradiotherapy.
Topics: 3' Untranslated Regions; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Capecitabine; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Genotype; Humans; Leucovorin; Male; Neoadjuvant Therapy; Neoplasm, Residual; Organoplatinum Compounds; Polymorphism, Genetic; Rectal Neoplasms; Sequence Deletion; Thymidylate Synthase | 2013 |
Bevacizumab-containing chemotherapy is safe in patients with unresectable metastatic colorectal cancer and a synchronous asymptomatic primary tumor.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Staging; Neoplasms, Multiple Primary; Organoplatinum Compounds; Oxaliplatin; Prognosis; Rectal Neoplasms; Retrospective Studies; Survival Rate; Young Adult | 2013 |
MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Neoplasm; Female; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Neoadjuvant Therapy; Neoplasm Proteins; Pilot Projects; Radiation Tolerance; Rectal Neoplasms; Retrospective Studies; RNA, Neoplasm; Thymidylate Synthase; Treatment Outcome | 2012 |
[A case report of successful treatment for rectosigmoid cancer with peritoneal dissemination after neoadjuvant chemoradiotherapy with XELOX and bevacizumab].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Middle Aged; Neoadjuvant Therapy; Oxaloacetates; Peritoneal Neoplasms; Rectal Neoplasms; Sigmoid Neoplasms | 2013 |
[A case of advanced rectal cancer with bladder carcinoma salvaged from myocardial infarction during operation, showing tumor regression by XELOX treatment, good quality of life].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Intraoperative Complications; Male; Myocardial Infarction; Neoplasms, Multiple Primary; Oxaloacetates; Quality of Life; Rectal Neoplasms; Salvage Therapy; Urinary Bladder Neoplasms | 2013 |
Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Rectal Neoplasms | 2002 |
Cardiac toxicity associated with capecitabine therapy.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diagnosis, Differential; Electrocardiography; Fluorouracil; Heart Diseases; Humans; Male; Middle Aged; Prodrugs; Rectal Neoplasms | 2003 |
Capecitabine-related neurotoxicity presenting as trismus.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Central Nervous System; Confusion; Deoxycytidine; Diagnosis, Differential; Electroencephalography; Eye Movements; Female; Fluorouracil; Gait Ataxia; Humans; Magnetic Resonance Imaging; Middle Aged; Rectal Neoplasms; Speech Disorders; Trismus | 2003 |
Anti-metastatic effect of capecitabine on human colon cancer xenografts in nude mouse rectum.
Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplasms; Deoxycytidine; Fluorouracil; Gastrointestinal Neoplasms; Green Fluorescent Proteins; Humans; Luminescent Proteins; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Thymidine Phosphorylase; Transplantation, Heterologous | 2004 |
The effects of capecitabine in Raynaud's disease: a case report.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Capecitabine; Deoxycytidine; Fluorouracil; Follow-Up Studies; Humans; Male; Raynaud Disease; Rectal Neoplasms; Recurrence; Risk Assessment; Severity of Illness Index; Vasoconstriction | 2005 |
Capecitabine as third line therapy in patients with advanced colorectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Capecitabine; Carcinoembryonic Antigen; Colonic Neoplasms; Deoxycytidine; Disease Progression; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Prodrugs; Rectal Neoplasms; Retrospective Studies; Survival Rate | 2005 |
Pre-operative chemo-radiotherapy improves the sphincter preservation rate in patients with rectal cancer located within 3 cm of the anal verge.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Confounding Factors, Epidemiologic; Deoxycytidine; Digestive System Surgical Procedures; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy, Adjuvant; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2006 |
Preoperative sequential short-term radiotherapy plus chemotherapy can induce complete remission in T3N2 rectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction | 2005 |
Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Disease-Free Survival; Female; Floxuridine; Fluorouracil; Humans; Immunohistochemistry; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Thymidine Phosphorylase; Up-Regulation | 2006 |
Concurrent oxaliplatin, capecitabine, and radiation therapy in the neoadjuvant therapy of rectal adenocarcinoma: can we get the right dose first?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Organoplatinum Compounds; Pyridines; Rectal Neoplasms | 2006 |
Can molecular imaging predict response to preoperative chemoradiation in patients with rectal cancer? A Fox Chase Cancer Center prospective experience.
Topics: Adenocarcinoma; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorodeoxyglucose F18; Fluorouracil; Humans; Male; Neoadjuvant Therapy; Positron-Emission Tomography; Radiotherapy; Rectal Neoplasms | 2005 |
Capecitabine as an alternative in a case of fluorouracil-induced photodermatitis.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Photosensitivity Disorders; Rectal Neoplasms | 2006 |
Capecitabine chemoradiation for rectal cancer after curative surgery.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Prodrugs; Radiotherapy Dosage; Rectal Neoplasms | 2006 |
Tumour regression and mesorectal lymph node changes after intensified neoadjuvant chemoradiation for carcinoma of the rectum.
Topics: Adenocarcinoma; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; CD83 Antigen; Dendritic Cells; Deoxycytidine; Female; Fluorouracil; Humans; Immunoglobulins; Irinotecan; Lymph Nodes; Male; Membrane Glycoproteins; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms | 2006 |
Intraventricular metastases from rectal-sigmoid adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cardiac Tamponade; Deoxycytidine; Dyspnea; Fatal Outcome; Female; Fluorouracil; Heart Neoplasms; Heart Ventricles; Humans; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Radiography; Rectal Neoplasms; Sigmoid Neoplasms; Ultrasonography | 2006 |
Preoperative chemoradiation in rectal cancer: Retrospective comparison between capecitabine and continuous infusion of 5-fluorouracil.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms; Retrospective Studies; Treatment Outcome | 2006 |
Epidermal growth factor receptor as a predictor of tumor downstaging in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Capecitabine; Combined Modality Therapy; Deoxycytidine; ErbB Receptors; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies | 2006 |
Hand-foot syndrome variant in a dihydropyrimidine dehydrogenase-deficient patient treated with capecitabine.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Deficiency Diseases; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Foot Dermatoses; Hand Dermatoses; Humans; Male; Middle Aged; Paresthesia; Prodrugs; Rectal Neoplasms; Syndrome | 2006 |
Preoperative chemoradiotherapy with capecitabine versus protracted infusion 5-fluorouracil for rectal cancer: a matched-pair analysis.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chi-Square Distribution; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Matched-Pair Analysis; Middle Aged; Neoplasm Recurrence, Local; Rectal Neoplasms; Retrospective Studies; Statistics, Nonparametric; Survival Analysis | 2006 |
Comparison of 5-fluorouracil/leucovorin and capecitabine in preoperative chemoradiotherapy for locally advanced rectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Radiotherapy Dosage; Rectal Neoplasms; Retrospective Studies | 2007 |
Optimal time interval between capecitabine intake and radiotherapy in preoperative chemoradiation for locally advanced rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Multivariate Analysis; Rectal Neoplasms; Remission Induction; Retrospective Studies | 2007 |
Toxicities and survival among octogenarians and nonagenarians with colorectal cancer treated with chemotherapy or concurrent chemoradiation therapy.
Topics: Age Factors; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colonic Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Leucovorin; Male; Rectal Neoplasms; Retrospective Studies; Survival; Treatment Outcome | 2007 |
Chemotherapy or no chemotherapy in clear margins after neoadjuvant chemoradiation in locally advanced rectal cancer: CHRONICLE. A randomised phase III trial of control vs. capecitabine plus oxaliplatin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Rectal Neoplasms | 2007 |
Adjuvant therapy for stage II and III colorectal cancer.
Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Leucovorin; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prodrugs; Rectal Neoplasms; Vitamin B Complex | 2007 |
A case of capecitabine-induced coronary microspasm in a patient with rectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Coronary Vasospasm; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Humans; Male; Mutation; Rectal Neoplasms | 2007 |
Capecitabine-induced headache responding to diltiazem.
Topics: Adult; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diltiazem; Female; Fluorouracil; Headache; Humans; Rectal Neoplasms | 2007 |
Phase II study of preoperative irradiation and chemotherapy with capecitabine in patients with locally advanced rectal carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Digestive System Surgical Procedures; Feasibility Studies; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Lymph Node Excision; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Radiotherapy, Adjuvant; Rectal Neoplasms; Treatment Outcome; Vitamin B Complex | 2007 |
[Evaluation of preoperative radiotherapy or chemoradiotherapy in sphincter preservation for locally advanced middle-low rectal cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Particle Accelerators; Preoperative Care; Radiotherapy, High-Energy; Rectal Neoplasms; Retrospective Studies | 2007 |
Preoperative radiotherapy and concomitant capecitabine treatment induce thymidylate synthase and thymidine phosphorylase mRNAs in rectal carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoembryonic Antigen; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Genetic Markers; Humans; Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Pyrimidines; Rectal Neoplasms; RNA, Messenger; Thymidine Phosphorylase; Thymidylate Synthase | 2007 |
[Laparoscopic ovarian transposition and cryopreservation of ovarian tissue before chemo-radiotherapy for rectal cancer].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Cryopreservation; Deoxycytidine; Female; Fluorouracil; Humans; Laparoscopy; Organoplatinum Compounds; Ovary; Oxaliplatin; Rectal Neoplasms | 2007 |
Neoadjuvant chemotherapy enables R0 resection of locally advanced rectal cancer in a patient with a previously irradiated pelvis.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Transitional Cell; Colonic Pouches; Deoxycytidine; Fluorouracil; Humans; Magnetic Resonance Imaging; Male; Organoplatinum Compounds; Oxaliplatin; Prostatic Neoplasms; Rectal Neoplasms; Urinary Bladder Neoplasms | 2007 |
Daily low-dose/continuous capecitabine combined with neo-adjuvant irradiation reduces VEGF and PDGF-BB levels in rectal carcinoma patients.
Topics: Antimetabolites, Antineoplastic; Becaplermin; Capecitabine; Carcinoma; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Humans; Neoadjuvant Therapy; Neovascularization, Pathologic; Pelvis; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rectal Neoplasms; Statistics as Topic; Vascular Endothelial Growth Factor A | 2008 |
Capecitabine-related cardiotoxicity: recognition and management.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colonic Neoplasms; Deoxycytidine; Female; Fluorouracil; Heart Diseases; Humans; Incidence; Male; Middle Aged; Prodrugs; Rectal Neoplasms | 2008 |
Preoperative chemoradiation with capecitabine in locally advanced rectal cancer.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Male; Middle Aged; Radiotherapy Dosage; Rectal Neoplasms | 2008 |
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Irinotecan; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Male; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Philadelphia Chromosome; Quinazolines; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes | 2008 |
Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil.
Topics: Administration, Oral; Angina Pectoris; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Dose-Response Relationship, Drug; Electrocardiography; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Rectal Neoplasms; Risk Assessment | 2002 |