Page last updated: 2024-11-08

cantharidin and Urinary Bladder Neoplasms

cantharidin has been researched along with Urinary Bladder Neoplasms in 4 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.

Research Excerpts

ExcerptRelevanceReference
"Treatment of human bladder cancer cells with cantharidin significantly decreased cell viability."5.42Cantharidin Induces Apoptosis Through the Calcium/PKC-Regulated Endoplasmic Reticulum Stress Pathway in Human Bladder Cancer Cells. ( Fang, KM; Huang, CF; Huang, KT; Lai, CH; Lee, KI; Liu, SH; Lu, TH; Su, CC; Su, YC; Wu, CC; Yen, CC, 2015)
"Treatment of human bladder cancer cells with cantharidin significantly decreased cell viability."1.42Cantharidin Induces Apoptosis Through the Calcium/PKC-Regulated Endoplasmic Reticulum Stress Pathway in Human Bladder Cancer Cells. ( Fang, KM; Huang, CF; Huang, KT; Lai, CH; Lee, KI; Liu, SH; Lu, TH; Su, CC; Su, YC; Wu, CC; Yen, CC, 2015)
" The toxic effects of mylabris on bladder are attributed to its active principle: cantharidin."1.33Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line. ( Huan, SK; Lee, HH; Liu, DZ; Wang, CC; Wu, CC, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuo, JH2
Shih, TY1
Lin, JP2
Lai, KC2
Lin, ML1
Yang, MD1
Chung, JG2
Su, CC1
Liu, SH1
Lee, KI1
Huang, KT1
Lu, TH1
Fang, KM1
Wu, CC2
Yen, CC1
Lai, CH1
Su, YC1
Huang, CF1
Chu, YL1
Yang, JS1
Kuo, HM1
Hsia, TC1
Huan, SK1
Lee, HH1
Liu, DZ1
Wang, CC1

Other Studies

4 other studies available for cantharidin and Urinary Bladder Neoplasms

ArticleYear
Cantharidin induces DNA damage and inhibits DNA repair-associated protein expressions in TSGH8301 human bladder cancer cell.
    Anticancer research, 2015, Volume: 35, Issue:2

    Topics: Cantharidin; Cell Line, Tumor; DNA Damage; DNA Repair; Humans; Microscopy, Confocal; Neoplasm Protei

2015
Cantharidin Induces Apoptosis Through the Calcium/PKC-Regulated Endoplasmic Reticulum Stress Pathway in Human Bladder Cancer Cells.
    The American journal of Chinese medicine, 2015, Volume: 43, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Calcium; Cantharidin; Caspase 3; Cell Line, Tumor; Endopl

2015
Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal pathways.
    International journal of oncology, 2010, Volume: 37, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cantharidin; Cell Line, Tumor; Cell Separation;

2010
Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line.
    Toxicology, 2006, Jun-01, Volume: 223, Issue:1-2

    Topics: Adenosine Triphosphate; Apoptosis; Blotting, Western; Cantharidin; Cell Line, Tumor; Cyclooxygenase

2006