Page last updated: 2024-11-08

cantharidin and Stevens-Johnson Syndrome

cantharidin has been researched along with Stevens-Johnson Syndrome in 1 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wolff, K1
Tappeiner, J1
Schreiner, E1

Other Studies

1 other study available for cantharidin and Stevens-Johnson Syndrome

ArticleYear
[Acantholysis. I. Pathomechanism of the cantharidine "acantholysis". An electron microscopic study].
    Archiv fur klinische und experimentelle Dermatologie, 1968, Volume: 232, Issue:3

    Topics: Animals; Cantharidin; Cell Membrane; Cytoplasm; Guinea Pigs; Microscopy, Electron; Pemphigus; Skin;

1968