Page last updated: 2024-11-08

cantharidin and Skin Neoplasms

cantharidin has been researched along with Skin Neoplasms in 8 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
" The dose-response relationship was determined, and the validity of the tetrazolium test was confirmed."1.26Dose response in the tetrazolium test for skin carcinogenicity. ( Iversen, OH, 1980)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, CC1
Yu, FS1
Fan, MJ1
Chen, YY1
Lien, JC1
Chou, YC1
Lu, HF1
Tang, NY1
Peng, SF1
Huang, WW1
Chung, JG1
SKJAEGGESTAD, O1
Iversen, OH1
Driedger, PE1
Blumberg, PM1
Brehm, K1
Hundeiker, M1
Raick, AN1
Bock, RH1

Reviews

1 review available for cantharidin and Skin Neoplasms

ArticleYear
Cantharidin.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 1976, Volume: 10

    Topics: Animals; Benzofurans; Cantharidin; Carcinogens; DNA Replication; Drug Evaluation, Preclinical; Femal

1976

Other Studies

7 other studies available for cantharidin and Skin Neoplasms

ArticleYear
Anticancer effects of cantharidin in A431 human skin cancer (Epidermoid carcinoma) cells in vitro and in vivo.
    Environmental toxicology, 2017, Volume: 32, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cantharidin; Carcinoma, Squamous Cell; Caspases; Cell Lin

2017
EXPERIMENTAL EPIDERMAL HYPERPLASIA IN MICE: RELATION TO CARCINOGENESIS.
    Acta pathologica et microbiologica Scandinavica. Supplementum, 1964

    Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Cantharidin; Carcinogenesis; Carcinogens; Cell Division;

1964
Dose response in the tetrazolium test for skin carcinogenicity.
    British journal of cancer, 1980, Volume: 41, Issue:3

    Topics: Animals; Cantharidin; Carcinogens; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Re

1980
Non-phorbol mouse skin tumor promoters do not mimic phorbol myristate acetate in its effects on chick embryo fibroblasts.
    International journal of cancer, 1978, Jul-15, Volume: 22, Issue:1

    Topics: Acetates; Animals; Anthralin; Cantharidin; Carcinogens; Cell Membrane; Chick Embryo; Cytochalasin B;

1978
[A method for the treatment of precancerous conditions of the skin].
    Zeitschrift fur Hautkrankheiten, 1974, Apr-01, Volume: 49, Issue:7

    Topics: Aged; Bandages; Biopsy; Cantharidin; Humans; Male; Methods; Precancerous Conditions; Skin Neoplasms;

1974
Cell proliferation and promoting action in skin carcinogenesis.
    Cancer research, 1974, Volume: 34, Issue:5

    Topics: Alcohols; Animals; Benz(a)Anthracenes; Cantharidin; Carcinogens; Cell Division; Cell Transformation,

1974
Treatment of palpebral warts with cantharon.
    American journal of ophthalmology, 1965, Volume: 60, Issue:3

    Topics: Cantharidin; Cornea; Eyelids; Humans; Papilloma; Skin Neoplasms

1965