Page last updated: 2024-11-08

cantharidin and Palmoplantaris Pustulosis

cantharidin has been researched along with Palmoplantaris Pustulosis in 7 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Research Excerpts

ExcerptRelevanceReference
" Using this assay we were able to demonstrate prostaglandin activity in dermal perfusates from 5 of 8 patients with contact dermatitis, and in blister fluid from 4 volunteers with contact dermatitis and 4 volunteers with cantharidin blisters."3.65Prostaglandin activity in human cutaneous inflammation: detection by radioimmunoassay. ( Goldyne, ME; Ryan, RJ; Winkelmann, RK, 1973)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grosfeld, JC4
Mighorst, JC4
den Hartog, BC2
van Ramshorst, AG2
Dubertret, L1
Bertaux, B1
Fosse, M1
Touraine, R1
Goldyne, ME1
Winkelmann, RK1
Ryan, RJ1
Piper, HG1
Hadlich, J1
Würbach, G1

Other Studies

7 other studies available for cantharidin and Palmoplantaris Pustulosis

ArticleYear
[Studies of the LDH level and the LDH isoenzyme pattern in cantharidine blister exudate of normal skin and in psoriasis].
    Nederlands tijdschrift voor geneeskunde, 1967, Nov-18, Volume: 111, Issue:46

    Topics: Blister; Cantharidin; Exudates and Transudates; Humans; Isoenzymes; L-Lactate Dehydrogenase; Psorias

1967
LDH isoenzymes in cantharidine blisters of the normal skin and psoriasis.
    Dermatologica, 1967, Volume: 135, Issue:6

    Topics: Blister; Cantharidin; Humans; Isoenzymes; L-Lactate Dehydrogenase; Psoriasis

1967
Psoriasis: a defect in the regulation of epidermal proteases, as shown by serial biopsies after cantharidin application.
    The British journal of dermatology, 1984, Volume: 110, Issue:4

    Topics: Cantharidin; Cell Movement; Endopeptidases; Epidermis; Humans; Neutrophils; Psoriasis; Serine Endope

1984
Prostaglandin activity in human cutaneous inflammation: detection by radioimmunoassay.
    Prostaglandins, 1973, Volume: 4, Issue:5

    Topics: Animals; Antibody Formation; Blister; Cantharidin; Cross Reactions; Dermatitis, Contact; Female; Hum

1973
[Fibrinolytic activity of the skin in psoriasis and various other dermatoses].
    Archiv fur klinische und experimentelle Dermatologie, 1967, Volume: 228, Issue:3

    Topics: Alopecia Areata; Antifibrinolytic Agents; Benzoates; Blister; Cantharidin; Fibrinolysis; Humans; Mal

1967
LDH isoenzymes in cantharidine blisters of the normal skin and psoriasis.
    Dermatologica, 1968, Volume: 136, Issue:4

    Topics: Blister; Cantharidin; Humans; Isoenzymes; L-Lactate Dehydrogenase; Psoriasis; Skin

1968
A study of the LDH level and the LDH isoenzyme pattern in cantharidin blister fluid in normal skin and in psoriasis.
    Dermatologica, 1968, Volume: 137, Issue:6

    Topics: Blister; Cantharidin; Histocytochemistry; Humans; Isoenzymes; L-Lactate Dehydrogenase; Psoriasis; Sk

1968