cantharidin has been researched along with Neurogenic Inflammation in 1 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
Neurogenic Inflammation: Inflammation caused by an injurious stimulus of peripheral neurons and resulting in release of neuropeptides which affect vascular permeability and help initiate proinflammatory and immune reactions at the site of injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We analysed human cantharidin-induced blister samples and inflammatory responses in TRPV1 transgenic mice." | 1.72 | 20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin. ( Ahluwalia, A; Bubb, K; Chen, J; Colas, R; Dalli, J; Hamers, A; Khambata, RS; Kumar, NA; Masucci, M; Montalvo Moreira, SA; Primus, CP; Rathod, K; Whitear, C, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamers, A | 1 |
| Primus, CP | 1 |
| Whitear, C | 1 |
| Kumar, NA | 1 |
| Masucci, M | 1 |
| Montalvo Moreira, SA | 1 |
| Rathod, K | 1 |
| Chen, J | 1 |
| Bubb, K | 1 |
| Colas, R | 1 |
| Khambata, RS | 1 |
| Dalli, J | 1 |
| Ahluwalia, A | 1 |
1 other study available for cantharidin and Neurogenic Inflammation
| Article | Year |
|---|---|
20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin.
Topics: Animals; Arachidonic Acid; Blister; Cantharidin; Edema; Humans; Hydroxyeicosatetraenoic Acids; Ligan | 2022 |