cantharidin has been researched along with Muscle Contraction in 8 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, NC | 1 |
| Burnstock, G | 1 |
| Khattab, MM | 1 |
| Al-Rawi, MB | 1 |
| Aleisa, AM | 1 |
| Knapp, J | 5 |
| Bokník, P | 5 |
| Linck, B | 3 |
| Lüss, H | 4 |
| Müller, FU | 4 |
| Nacke, P | 3 |
| Neumann, J | 5 |
| Vahlensieck, U | 3 |
| Schmitz, W | 5 |
| Huke, S | 2 |
| Müller, T | 2 |
| Gombosová, I | 1 |
| Waurick, R | 1 |
| Van Aken, H | 1 |
| Petertönjes, L | 1 |
| Hong, SJ | 1 |
1 review available for cantharidin and Muscle Contraction
| Article | Year |
|---|---|
Contractility and inhibition of protein phosphatases by cantharidin.
Topics: Animals; Cantharidin; Enzyme Inhibitors; Heart; Humans; Muscle Contraction; Muscle Proteins; Muscle, | 1998 |
7 other studies available for cantharidin and Muscle Contraction
| Article | Year |
|---|---|
Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; | 2004 |
Postjunctional synergism of norepinephrine with ATP and diadenosine tetraphosphate in Guinea pig vas deferens. Role of protein kinase C and Myosin light chain phosphatase.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Cantharidin; Dinucleoside Phosphat | 2007 |
The effect of the protein phosphatases inhibitor cantharidin on beta-adrenoceptor-mediated vasorelaxation.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Cantharidin; Cattle; Cells, Cultured | 1997 |
The mechanism of action of cantharidin in smooth muscle.
Topics: Animals; Blotting, Northern; Calcium; Cantharidin; Catalysis; Cattle; Cells, Cultured; Cytosol; Enzy | 1998 |
Effect of 2,3-butanedione monoxime on force of contraction and protein phosphorylation in bovine smooth muscle.
Topics: Animals; Autoradiography; Cantharidin; Cattle; Cells, Cultured; Coronary Vessels; Diacetyl; Electrop | 1999 |
Cantharidin enhances norepinephrine-induced vasoconstriction in an endothelium-dependent fashion.
Topics: Animals; Aorta, Thoracic; Cantharidin; Catalysis; Drug Synergism; Endothelium, Vascular; Enzyme Inhi | 2000 |
Inhibition of mouse neuromuscular transmission and contractile function by okadaic acid and cantharidin.
Topics: Animals; Cantharidin; Cobra Cardiotoxin Proteins; Diaphragm; Dose-Response Relationship, Drug; Elect | 2000 |