Page last updated: 2024-11-08

cantharidin and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

cantharidin has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 1 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, X1
Cai, X1
Yang, J1
Chen, J1
Guo, C1
Cao, P1

Other Studies

1 other study available for cantharidin and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
Cantharidin Overcomes Imatinib Resistance by Depleting BCR-ABL in Chronic Myeloid Leukemia.
    Molecules and cells, 2016, Volume: 39, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Cell Cycle Checkpoints; DNA Damage; Dru

2016