cantharidin has been researched along with Heart Failure in 2 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Linck, B | 2 |
| Boknik, P | 2 |
| Knapp, J | 2 |
| Müller, FU | 2 |
| Neumann, J | 2 |
| Schmitz, W | 2 |
| Vahlensieck, U | 1 |
| Lüss, H | 1 |
2 other studies available for cantharidin and Heart Failure
| Article | Year |
|---|---|
Effects of cantharidin on force of contraction and phosphatase activity in nonfailing and failing human hearts.
Topics: Analysis of Variance; Cantharidin; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Failu | 1996 |
Activation and inactivation of cAMP-response element-mediated gene transcription in cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cantharidin; Cardiotonic Agents; Cell Cycle | 2001 |