cantharidin has been researched along with Experimental Neoplasms in 10 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The findings of damaged mitochondria in the cantharidin treated Hep 3B cells in this study suggest that cantharidin can induce acute and lethal toxic effects on Hep 3B cells by inhibiting the mitochondria energy system." | 1.31 | Cytotoxic effects of cantharidin on the growth of normal and carcinoma cells. ( Hsieh, KJ; Wang, CC; Wu, CH; Yang, LL; Yen, KY, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, S | 1 |
| Li, J | 1 |
| Cheng, P | 1 |
| Zeng, Z | 1 |
| Zhang, C | 1 |
| Duan, H | 1 |
| Pu, K | 1 |
| Wang, Z | 1 |
| Kuang, G | 1 |
| Yu, Z | 1 |
| Li, A | 1 |
| Zhou, D | 1 |
| Huang, Y | 1 |
| POUND, AW | 1 |
| WITHERS, HR | 1 |
| SKJAEGGESTAD, O | 1 |
| Liu, JY | 1 |
| Zhang, BX | 1 |
| Sun, JL | 1 |
| Chen, RT | 1 |
| Hua, Z | 1 |
| Yang, JL | 1 |
| Han, JX | 1 |
| Zhang, SY | 1 |
| Lü, FL | 1 |
| Xü, B | 1 |
| Zhang, SQ | 1 |
| Wang, CC | 1 |
| Wu, CH | 1 |
| Hsieh, KJ | 1 |
| Yen, KY | 1 |
| Yang, LL | 1 |
| Driedger, PE | 1 |
| Blumberg, PM | 1 |
| Raick, AN | 1 |
10 other studies available for cantharidin and Experimental Neoplasms
| Article | Year |
|---|---|
Charge-Reversal Polymer Nano-modulators for Photodynamic Immunotherapy of Cancer.
Topics: Animals; Antineoplastic Agents; Cantharidin; Colonic Neoplasms; Immunologic Factors; Immunotherapy; | 2021 |
Light-activatable dual prodrug polymer nanoparticle for precise synergistic chemotherapy guided by drug-mediated computed tomography imaging.
Topics: Animals; Antineoplastic Agents; Cantharidin; Contrast Media; HeLa Cells; Humans; Light; Mice; Nanopa | 2019 |
THE INFLUENCE OF SOME IRRITANT CHEMICALS AND SCARIFICATION ON TUMOUR INITIATION BY URETHANE IN MICE.
Topics: Acetates; Acetone; Cantharidin; Cell Transformation, Neoplastic; Dermabrasion; Iodoacetates; Irritan | 1963 |
EXPERIMENTAL EPIDERMAL HYPERPLASIA IN MICE: RELATION TO CARCINOGENESIS.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Cantharidin; Carcinogenesis; Carcinogens; Cell Division; | 1964 |
[Studies on antitumor chemotherapeutic agents. II. Synthesis of cantharidine derivatives and analogues].
Topics: Animals; Antineoplastic Agents; Cantharidin; Mice; Neoplasms, Experimental; Structure-Activity Relat | 1983 |
Studies on antitumor actions of cantharidin.
Topics: Animals; Cantharidin; Female; Immunity, Cellular; Injections, Intraperitoneal; Male; Mice; Neoplasms | 1980 |
[A study on antitumor chemotherapeutic agents--synthesis of N-cantharidine derivatives (author's transl)].
Topics: Animals; Antineoplastic Agents; Cantharidin; Mice; Neoplasms, Experimental; Rats | 1981 |
Cytotoxic effects of cantharidin on the growth of normal and carcinoma cells.
Topics: Animals; Cantharidin; Cell Cycle; Cell Death; Coleoptera; DNA; Flow Cytometry; Humans; Irritants; Mi | 2000 |
Non-phorbol mouse skin tumor promoters do not mimic phorbol myristate acetate in its effects on chick embryo fibroblasts.
Topics: Acetates; Animals; Anthralin; Cantharidin; Carcinogens; Cell Membrane; Chick Embryo; Cytochalasin B; | 1978 |
Cell proliferation and promoting action in skin carcinogenesis.
Topics: Alcohols; Animals; Benz(a)Anthracenes; Cantharidin; Carcinogens; Cell Division; Cell Transformation, | 1974 |