Page last updated: 2024-11-08

cantharidin and Equine Diseases

cantharidin has been researched along with Equine Diseases in 6 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Research Excerpts

ExcerptRelevanceReference
"Blister beetle poisoning is not universally fatal in equids."1.30Clinical features of blister beetle poisoning in equids: 70 cases (1983-1996). ( Edwards, WC; Helman, RG, 1997)
"Crystalline cantharidin in an alfalfa cake or in aqueous suspension was given to 8 horses at a dosage level of 450 to 489 micrograms/kg of body weight (group 1) and 2 horses at a dosage level of 720 micrograms/kg (group 2) via nasogastric tube."1.27Experimental cantharidiasis in the horse. ( Rolf, LL; Shawley, RV, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shawley, RV1
Rolf, LL1
Beasley, VR1
Wolf, GA1
Fischer, DC1
Ray, AC3
Edwards, WC4
Post, LO1
Hurst, JM1
Reagor, JC2
Helman, RG1
Edwards, RM1
Ogden, L1
Whaley, M1
Kyle, AL1
Murphy, MJ1

Other Studies

6 other studies available for cantharidin and Equine Diseases

ArticleYear
Experimental cantharidiasis in the horse.
    American journal of veterinary research, 1984, Volume: 45, Issue:11

    Topics: Animals; Blood Proteins; Body Temperature; Calcium; Cantharidin; Carbon Dioxide; Creatine Kinase; Fe

1984
Cantharidin toxicosis in horses.
    Journal of the American Veterinary Medical Association, 1983, Feb-01, Volume: 182, Issue:3

    Topics: Animal Feed; Animals; Cantharidin; Coleoptera; Female; Food Contamination; Horse Diseases; Horses; P

1983
Evaluation of an analytical method for the diagnosis of cantharidin toxicosis due to ingestion of blister beetles (Epicauta lemniscata) by horses and sheep.
    American journal of veterinary research, 1980, Volume: 41, Issue:6

    Topics: Animals; Cantharidin; Chromatography, Liquid; Coleoptera; Horse Diseases; Horses; Sheep; Sheep Disea

1980
Clinical features of blister beetle poisoning in equids: 70 cases (1983-1996).
    Journal of the American Veterinary Medical Association, 1997, Oct-15, Volume: 211, Issue:8

    Topics: Animals; Calcium; Cantharidin; Coleoptera; Colic; Digestive System; Equidae; Female; Gastrointestina

1997
Cantharidin content of two species of Oklahoma blister beetles associated with toxicosis in horses.
    Veterinary and human toxicology, 1989, Volume: 31, Issue:5

    Topics: Animals; Cantharidin; Coleoptera; Female; Horse Diseases; Horses; Male

1989
Etiologic agents, incidence, and improved diagnostic methods of cantharidin toxicosis in horses.
    American journal of veterinary research, 1989, Volume: 50, Issue:2

    Topics: Animals; Cantharidin; Coleoptera; Feces; Gastrointestinal Contents; Horse Diseases; Horses

1989