cantharidin has been researched along with Edema in 5 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine salicylate (MR-800) has been tested as a topical antiinflammatory agent in several models of skin inflammation in rodents, such as mouse ear dermatitis induced by croton oil, cantharidin or zymosan, and rat paw oedema induced by PAF." | 7.69 | Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema. ( Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Leonardi, G, 1994) |
| "Papaverine salicylate (MR-800) has been tested as a topical antiinflammatory agent in several models of skin inflammation in rodents, such as mouse ear dermatitis induced by croton oil, cantharidin or zymosan, and rat paw oedema induced by PAF." | 3.69 | Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema. ( Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Leonardi, G, 1994) |
| "BRL 20459 is a novel compound which displays anti-inflammatory activity when applied topically in the croton oil and cantharadin rat ear inflammation models." | 3.67 | BRL 20459, a novel topically active non-steroidal anti-inflammatory drug. ( Boyle, EA; Green, AP; Mangan, FR; Randall, KE; Thomson, MJ, 1984) |
| "We analysed human cantharidin-induced blister samples and inflammatory responses in TRPV1 transgenic mice." | 1.72 | 20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin. ( Ahluwalia, A; Bubb, K; Chen, J; Colas, R; Dalli, J; Hamers, A; Khambata, RS; Kumar, NA; Masucci, M; Montalvo Moreira, SA; Primus, CP; Rathod, K; Whitear, C, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamers, A | 1 |
| Primus, CP | 1 |
| Whitear, C | 1 |
| Kumar, NA | 1 |
| Masucci, M | 1 |
| Montalvo Moreira, SA | 1 |
| Rathod, K | 1 |
| Chen, J | 1 |
| Bubb, K | 1 |
| Colas, R | 1 |
| Khambata, RS | 1 |
| Dalli, J | 1 |
| Ahluwalia, A | 1 |
| Ivetic Tkalcevic, V | 1 |
| Hrvacic, B | 1 |
| Bosnar, M | 1 |
| Cuzic, S | 1 |
| Bosnjak, B | 1 |
| Erakovic Haber, V | 1 |
| Glojnaric, I | 1 |
| Gábor, M | 1 |
| Green, AP | 1 |
| Mangan, FR | 1 |
| Thomson, MJ | 1 |
| Randall, KE | 1 |
| Boyle, EA | 1 |
| de Bernardis, E | 1 |
| Leonardi, G | 1 |
| Caruso, A | 1 |
| Cutuli, VM | 1 |
| Amico-Roxas, M | 1 |
1 review available for cantharidin and Edema
| Article | Year |
|---|---|
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Derm | 2003 |
4 other studies available for cantharidin and Edema
| Article | Year |
|---|---|
20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin.
Topics: Animals; Arachidonic Acid; Blister; Cantharidin; Edema; Humans; Hydroxyeicosatetraenoic Acids; Ligan | 2022 |
Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azithromycin; Can | 2012 |
BRL 20459, a novel topically active non-steroidal anti-inflammatory drug.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Binding, Competitive; Cantharidin; Carra | 1984 |
Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cantharidin; Croton Oil; Dermatitis; Dose-Response | 1994 |