Page last updated: 2024-11-08

cantharidin and Dermatitis

cantharidin has been researched along with Dermatitis in 8 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Dermatitis: Any inflammation of the skin.

Research Excerpts

ExcerptRelevanceReference
"Papaverine salicylate (MR-800) has been tested as a topical antiinflammatory agent in several models of skin inflammation in rodents, such as mouse ear dermatitis induced by croton oil, cantharidin or zymosan, and rat paw oedema induced by PAF."7.69Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema. ( Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Leonardi, G, 1994)
" These insects contain cantharidin, a vesicant substance that can cause poisoning by ingestion and dermatitis by direct contact."4.31Blister Beetle Dermatitis Outbreaks in Mali. ( Aigle, L; Bologna, MA; François, M; Grau, M; Holterbach, L; Le Gall, P; Pommier de Santi, V; Valois, A; Velut, G, 2023)
" The most well-known family, Meloidae, has more than 200 species known for causing a blistering dermatitis in humans by emitting the substance cantharidin, which has been pharmacologically used as a vesicant and can cause deleterious effects if ingested."3.91What's eating you? blister beetles revisited. ( Elgart, GW; Elston, DM; Hodge, BD, 2019)
"Papaverine salicylate (MR-800) has been tested as a topical antiinflammatory agent in several models of skin inflammation in rodents, such as mouse ear dermatitis induced by croton oil, cantharidin or zymosan, and rat paw oedema induced by PAF."3.69Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema. ( Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Leonardi, G, 1994)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Velut, G1
Grau, M1
Valois, A1
Holterbach, L1
François, M1
Le Gall, P1
Aigle, L1
Pommier de Santi, V1
Bologna, MA1
Hodge, BD1
Elgart, GW1
Elston, DM1
Maynard-Burrows, CL1
Mclennan, JV1
Nicholson-Roberts, TC1
Takano, H1
Gábor, M1
FREGERT, S1
RORSMAN, H1
KAMINSKY, A1
KAMINSKY, CA1
BRAUNSTEIN, S1
Mumcuoglu, Y1
Rufli, T1
de Bernardis, E1
Leonardi, G1
Caruso, A1
Cutuli, VM1
Amico-Roxas, M1

Reviews

1 review available for cantharidin and Dermatitis

ArticleYear
Models of acute inflammation in the ear.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Derm

2003

Other Studies

7 other studies available for cantharidin and Dermatitis

ArticleYear
Blister Beetle Dermatitis Outbreaks in Mali.
    Military medicine, 2023, 08-29, Volume: 188, Issue:9-10

    Topics: Animals; Cantharidin; Coleoptera; Dermatitis; Disease Outbreaks; Mali

2023
What's eating you? blister beetles revisited.
    Cutis, 2019, Volume: 104, Issue:6

    Topics: Animals; Cantharidin; Coleoptera; Dermatitis; Humans

2019
Blister beetle dermatitis caused by cantharidin in South Sudan in Op TRENTON: a case series.
    BMJ military health, 2021, Volume: 167, Issue:5

    Topics: Animals; Cantharidin; Coleoptera; Dermatitis; Research; South Sudan

2021
BASOPHIL LEUKOCYTES IN INTRACUTANEOUS TEST REACTIONS TO METALS.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Basophils; Cantharidin; Chromates; Cobalt; Dermatitis; Dermatitis, Contact; Exudates and Transudates

1963
[Iatrogenic and accidental dermatosis caused by cantharidine].
    La Semana medica, 1961, Nov-20, Volume: 119

    Topics: Cantharidin; Dermatitis; Humans; Iatrogenic Disease; Skin Diseases

1961
[Dermatologic entomology. The practical medical importance of mites and insects in Switzerland and its surrounding regions. 15. Coleoptera/beetles].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1980, Nov-25, Volume: 69, Issue:47

    Topics: Allergens; Cantharidin; Coleoptera; Dermatitis; Humans; Insect Vectors

1980
Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema.
    Agents and actions, 1994, Volume: 42, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cantharidin; Croton Oil; Dermatitis; Dose-Response

1994