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cantharidin and Cardiomyopathies, Primary

cantharidin has been researched along with Cardiomyopathies, Primary in 2 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Research Excerpts

ExcerptRelevanceReference
"The most common arrhythmias associated with the high doses of cantharidin were frequent ventricular ectopics, ventricular tachycardia, ventricular fibrillation or asytole."5.26A model of cardiac arrhythmias and sudden death: cantharidin-induced toxic cardiomyopathy. ( Ferris, JA; Friesen, JM; Fung, HY; Rabkin, SW, 1979)
"The most common arrhythmias associated with the high doses of cantharidin were frequent ventricular ectopics, ventricular tachycardia, ventricular fibrillation or asytole."1.26A model of cardiac arrhythmias and sudden death: cantharidin-induced toxic cardiomyopathy. ( Ferris, JA; Friesen, JM; Fung, HY; Rabkin, SW, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Youyou, Z1
Yalei, Y1
Jie, Z1
Chuhuai, G1
Liang, L1
Liang, R1
Rabkin, SW1
Friesen, JM1
Ferris, JA1
Fung, HY1

Other Studies

2 other studies available for cantharidin and Cardiomyopathies, Primary

ArticleYear
Molecular biomarkers of cantharidin-induced cardiotoxicity in Sprague-Dawley rats: Troponin T, vascular endothelial growth factor and hypoxia inducible factor-1α.
    Journal of applied toxicology : JAT, 2020, Volume: 40, Issue:8

    Topics: Animals; Biomarkers; Cantharidin; Cardiomyopathies; Cardiotoxicity; Dose-Response Relationship, Drug

2020
A model of cardiac arrhythmias and sudden death: cantharidin-induced toxic cardiomyopathy.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Blood Chemical Analysis; Cantharidin; Cardiomyopathies; Death, Sudden

1979