cantharidin has been researched along with Cancer of Mouth in 4 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most of oral cancer is histopathologically diagnosed as oral squamous cell carcinoma (OSCC)." | 1.43 | Cantharidin Induced Oral Squamous Cell Carcinoma Cell Apoptosis via the JNK-Regulated Mitochondria and Endoplasmic Reticulum Stress-Related Signaling Pathways. ( Chen, MK; Kuo, CY; Lee, KI; Liu, SH; Su, CC; Tang, CH, 2016) |
| "Chemosensitivity of salivary gland and oral cancer cell lines to 14 antitumor drugs was tested using a tetrazolium-based colorimetric assay and the relative antitumor activity (RAA) of the drugs was compared." | 1.28 | Chemosensitivity of salivary gland and oral cancer cell lines. ( Chen, JY; Liu, B; Situ, ZQ; Wang, W; Wu, JZ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weng, JR | 1 |
| Dokla, EME | 1 |
| Bai, LY | 1 |
| Chen, CS | 1 |
| Chiu, SJ | 1 |
| Shieh, TM | 1 |
| Xi, Y | 1 |
| Garshott, DM | 1 |
| Brownell, AL | 1 |
| Yoo, GH | 1 |
| Lin, HS | 1 |
| Freeburg, TL | 1 |
| Yoo, NG | 1 |
| Kaufman, RJ | 1 |
| Callaghan, MU | 1 |
| Fribley, AM | 1 |
| Su, CC | 1 |
| Lee, KI | 1 |
| Chen, MK | 1 |
| Kuo, CY | 1 |
| Tang, CH | 1 |
| Liu, SH | 1 |
| Wu, JZ | 1 |
| Situ, ZQ | 1 |
| Chen, JY | 1 |
| Liu, B | 1 |
| Wang, W | 1 |
4 other studies available for cantharidin and Cancer of Mouth
| Article | Year |
|---|---|
A 5' AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Autophagy; Benzeneacetamides; Canth | 2018 |
Cantharidins induce ER stress and a terminal unfolded protein response in OSCC.
Topics: Activating Transcription Factor 4; Animals; Antineoplastic Agents; Apoptosis; Arylamine N-Acetyltran | 2015 |
Cantharidin Induced Oral Squamous Cell Carcinoma Cell Apoptosis via the JNK-Regulated Mitochondria and Endoplasmic Reticulum Stress-Related Signaling Pathways.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cantharidin; Carcinoma, Squamous Cell; Cell Lin | 2016 |
Chemosensitivity of salivary gland and oral cancer cell lines.
Topics: Cantharidin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Salivary Gland Neopla | 1992 |