Page last updated: 2024-11-08

cantharidin and Asthma

cantharidin has been researched along with Asthma in 2 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Theophylline levels in plasma, erythrocytes and cantharides-induced blister fluid (BF) have been correlated with peak expiratory flow (PEF) in asthmatic patients."7.68Correlations between theophylline concentrations in plasma, erythrocytes and cantharides-induced blister fluid and peak expiratory flow in asthma patients. ( Arnaud, A; Bruguerolle, B; Philip-Joet, F; Reynaud, M, 1992)
"Theophylline levels in plasma, erythrocytes and cantharides-induced blister fluid (BF) have been correlated with peak expiratory flow (PEF) in asthmatic patients."3.68Correlations between theophylline concentrations in plasma, erythrocytes and cantharides-induced blister fluid and peak expiratory flow in asthma patients. ( Arnaud, A; Bruguerolle, B; Philip-Joet, F; Reynaud, M, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Philip-Joet, F1
Bruguerolle, B1
Reynaud, M1
Arnaud, A1
Kimura, I1
Tanizaki, Y1
Takahashi, K1
Saito, K1
Ueda, N1

Other Studies

2 other studies available for cantharidin and Asthma

ArticleYear
Correlations between theophylline concentrations in plasma, erythrocytes and cantharides-induced blister fluid and peak expiratory flow in asthma patients.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:5

    Topics: Asthma; Blister; Body Fluids; Cantharidin; Dose-Response Relationship, Drug; Erythrocytes; Humans; I

1992
Emergence of basophils at sites of local allergic reactions using a skin vesicle test.
    Clinical allergy, 1974, Volume: 4, Issue:3

    Topics: Allergens; Asthma; Basophils; Blister; Blood Cell Count; Cantharidin; Dermatitis, Atopic; Eosinophil

1974