cantharidin has been researched along with Acantholysis in 15 studies
Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.
Acantholysis: Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cantharidin has been used to induce acantholysis in vivo." | 7.67 | Cantharidin-induced acantholysis. ( Piérard, GE; Piérard-Franchimont, C, 1988) |
| "Acantholysis is a feature of disorders such as Hailey-Hailey disease and Darier's disease." | 5.29 | Cantharidin-induced acantholysis: adhesion molecules, proteases, and related proteins. ( Burge, SM; Dean, D; Yell, JA, 1994) |
| "Cantharidin has been used to induce acantholysis in vivo." | 3.67 | Cantharidin-induced acantholysis. ( Piérard, GE; Piérard-Franchimont, C, 1988) |
| "Acantholysis is a feature of disorders such as Hailey-Hailey disease and Darier's disease." | 1.29 | Cantharidin-induced acantholysis: adhesion molecules, proteases, and related proteins. ( Burge, SM; Dean, D; Yell, JA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WEAKLEY, DR | 3 |
| EINBINDER, JM | 3 |
| STOUGHTON, RB | 1 |
| BAGATELL, F | 1 |
| CHORZELSKI, T | 2 |
| LANGNER, A | 2 |
| GOMEZORBANEJA, J | 1 |
| AGUILAR, R | 1 |
| DECKER, RH | 2 |
| BAGATELL, FK | 1 |
| Yell, JA | 2 |
| Burge, SM | 2 |
| Dean, D | 2 |
| Piérard-Franchimont, C | 1 |
| Piérard, GE | 1 |
| Bertaux, B | 1 |
| Prost, C | 1 |
| Heslan, M | 1 |
| Dubertret, L | 1 |
| Stüttgen, G | 1 |
| Neumann, D | 1 |
15 other studies available for cantharidin and Acantholysis
| Article | Year |
|---|---|
Observations on the biochemical genesis of acantholysis.
Topics: Acantholysis; Blister; Cantharidin; Humans; Skin | 1961 |
The nature of cantharidin acantholysis.
Topics: Acantholysis; Cantharidin; Humans; Skin | 1959 |
The mechanism of cantharidin acantholysis.
Topics: Acantholysis; Blister; Cantharidin; Humans; Liver; Skin; Spleen | 1962 |
Enzymes, acantholysis, and pemphigus.
Topics: Acantholysis; Adenine Nucleotides; Cantharidin; Humans; Pemphigus; Phosphates; Skin | 1962 |
[Effect of magnesium ions on acantholysis produced artificially in vitro with the aid of cantharidin].
Topics: Acantholysis; Blister; Cantharidin; In Vitro Techniques; Ions; Magnesium; Skin | 1962 |
[Effect of magnesium ions on acantholysis produced artificially in vitro with the aid of cantharidin].
Topics: Acantholysis; Blister; Cantharidin; In Vitro Techniques; Ions; Magnesium; Skin | 1962 |
[PROTECTION EXERCISED BY THE STEROIDS ON THE SKIN IN THE PRESENCE OF EXPERIMENTAL CANTHARIDINIC ACANTHOLYSIS].
Topics: Acantholysis; Biopsy; Cantharidin; Dermatology; Dexamethasone; Hydrocortisone; Pathology; Prednisolo | 1963 |
MECHANISM OF ACANTHOLYSIS: THE EFFECT OF CANTHARIDIN ON OXIDATIVE PHOSPHORYLATION.
Topics: Acantholysis; Cantharidin; Dinitrophenols; Glutamates; Histocytochemistry; Liver; Metabolism; Methyl | 1964 |
STUDIES ON BIOLOGICAL FACTORS IN ACANTHOLYSIS.
Topics: Acantholysis; Biological Factors; Cantharidin; Histology; Pharmacology; Rats; Research; Skin | 1964 |
Cantharidin-induced acantholysis: adhesion molecules, proteases, and related proteins.
Topics: Acantholysis; Cantharidin; Cell Adhesion Molecules; Cytoskeletal Proteins; Desmoplakins; Fibrinogen; | 1994 |
Cantharidin-induced acantholysis in Darier's disease: does acantholysis initiate dyskeratosis?
Topics: Acantholysis; Adult; Basement Membrane; Cantharidin; Collagen; Cytoskeletal Proteins; Darier Disease | 1994 |
Cantharidin-induced acantholysis.
Topics: Acantholysis; Administration, Topical; Biopsy; Cantharidin; DNA Replication; Humans; Skin; Skin Dise | 1988 |
Cantharide acantholysis: endogenous protease activation leading to desmosomal plaque dissolution.
Topics: Acantholysis; Cantharidin; Cells, Cultured; Desmosomes; Humans; Intermediate Filaments; Peptide Hydr | 1988 |
[Isomorphic structure of cantharidin-blisters in various bullous dermatoses].
Topics: Acantholysis; Adult; Blister; Cantharidin; Dermatitis Herpetiformis; Drug Eruptions; Epidermolysis B | 1970 |
Activation of a protein kinase during acantholysis.
Topics: Acantholysis; Adenosine Triphosphate; Animals; Cantharidin; Cattle; Culture Techniques; Enzyme Activ | 1971 |