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candesartan cilexetil and Reperfusion Injury

candesartan cilexetil has been researched along with Reperfusion Injury in 4 studies

candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
" In human umbilical endothelial cells, candesartan increased the eNOS protein level AT2-R dependently, inhibited the expression of nicotinamide adenine dinucleotide phosphate oxidase subunits and angiotensin II-induced intracellular reactive oxygen species and nitric oxide, and promoted the extracellular release of nitric oxide, suggesting that it augmented the bioavailability of nitric oxide."1.35Protective mechanisms of the angiotensin II type 1 receptor blocker candesartan against cerebral ischemia: in-vivo and in-vitro studies. ( Kanematsu, Y; Kinouchi, T; Kitazato, KT; Liu, H; Nagahiro, S; Tada, Y; Tamura, T; Uno, M; Yagi, K, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Lapi, D1
Cammalleri, M1
Dal Monte, M1
Di Maro, M1
Santillo, M1
Belfiore, A1
Nasti, G1
Damiano, S1
Trio, R1
Chiurazzi, M1
De Conno, B1
Serao, N1
Mondola, P1
Colantuoni, A1
Guida, B1
Liu, H1
Kitazato, KT1
Uno, M1
Yagi, K1
Kanematsu, Y1
Tamura, T1
Tada, Y1
Kinouchi, T1
Nagahiro, S1
Araya, J2
Tsuruma, T2
Hirata, K2
Yagihashi, A2
Meguro, M1
Kawakami, M1
Yanai, Y1
Watanabe, N2

Other Studies

4 other studies available for candesartan cilexetil and Reperfusion Injury

ArticleYear
The Effects of Angiotensin II or Angiotensin 1-7 on Rat Pial Microcirculation during Hypoperfusion and Reperfusion Injury: Role of Redox Stress.
    Biomolecules, 2021, 12-10, Volume: 11, Issue:12

    Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Female; Male; Microcircu

2021
Protective mechanisms of the angiotensin II type 1 receptor blocker candesartan against cerebral ischemia: in-vivo and in-vitro studies.
    Journal of hypertension, 2008, Volume: 26, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain Ischemia

2008
The regulation of HGF and TGF-beta by an angiotensin II type 1 receptor antagonist in hepatic ischemia-reperfusion injury.
    Transplantation proceedings, 2003, Volume: 35, Issue:1

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Enzyme-Linked Immunos

2003
TCV-116, an angiotensin II type 1 receptor antagonist, reduces hepatic ischemia-reperfusion injury in rats.
    Transplantation, 2002, Feb-27, Volume: 73, Issue:4

    Topics: Alanine Transaminase; Angiotensin Receptor Antagonists; Animals; Aspartate Aminotransferases; Benzim

2002