candesartan cilexetil has been researched along with Myocarditis in 5 studies
candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the effect of a new angiotensin II type 1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-([2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl)-1H-benz imi dazole-7- carboxylate (TCV-116), in an animal model of viral myocarditis induced by encephalomyocarditis virus." | 7.69 | An angiotensin II receptor antagonist reduces myocardial damage in an animal model of myocarditis. ( Matsumori, A; Sasayama, S; Tanaka, A; Wang, W, 1994) |
| "We examined effects of an angiotensin-II receptor blockers, candesartan cilexetil, in rats with dilated cardiomyopathy after autoimmune myocarditis." | 3.73 | Effects of angiotensin-II receptor blocker candesartan cilexetil in rats with dilated cardiomyopathy. ( Aizawa, Y; Inoue, M; Kashimura, T; Kodama, M; Ma, M; Saito, Y; Shirai, K; Suresh, PS; Tachikawa, H; Wahed, MI; Watanabe, K, 2005) |
| "This study examined the role of angiotensin II (Ang-II) in a murine model of viral myocarditis." | 3.72 | Attenuation of virus-induced myocardial injury by inhibition of the angiotensin II type 1 receptor signal and decreased nuclear factor-kappa B activation in knockout mice. ( Matsumori, A; Miyamoto, T; Sasayama, S; Shioi, T; Uchiyama, K; Yamamoto, K, 2003) |
| " We investigated the effect of a new angiotensin II type 1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-([2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl)-1H-benz imi dazole-7- carboxylate (TCV-116), in an animal model of viral myocarditis induced by encephalomyocarditis virus." | 3.69 | An angiotensin II receptor antagonist reduces myocardial damage in an animal model of myocarditis. ( Matsumori, A; Sasayama, S; Tanaka, A; Wang, W, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arumugam, S | 1 |
| Thandavarayan, RA | 1 |
| Palaniyandi, SS | 1 |
| Giridharan, VV | 1 |
| Arozal, W | 1 |
| Sari, FR | 1 |
| Soetikno, V | 1 |
| Harima, M | 1 |
| Suzuki, K | 1 |
| Kodama, M | 2 |
| Watanabe, K | 2 |
| Yamamoto, K | 1 |
| Shioi, T | 1 |
| Uchiyama, K | 1 |
| Miyamoto, T | 1 |
| Sasayama, S | 3 |
| Matsumori, A | 3 |
| Shirai, K | 1 |
| Ma, M | 1 |
| Wahed, MI | 1 |
| Inoue, M | 1 |
| Saito, Y | 1 |
| Suresh, PS | 1 |
| Kashimura, T | 1 |
| Tachikawa, H | 1 |
| Aizawa, Y | 1 |
| Tanaka, A | 1 |
| Wang, W | 1 |
1 review available for candesartan cilexetil and Myocarditis
| Article | Year |
|---|---|
Immunomodulating agents for the management of heart failure with myocarditis and cardiomyopathy--lessons from animal experiments.
Topics: Adjuvants, Immunologic; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; B | 1995 |
4 other studies available for candesartan cilexetil and Myocarditis
| Article | Year |
|---|---|
Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzym | 2012 |
Attenuation of virus-induced myocardial injury by inhibition of the angiotensin II type 1 receptor signal and decreased nuclear factor-kappa B activation in knockout mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds | 2003 |
Effects of angiotensin-II receptor blocker candesartan cilexetil in rats with dilated cardiomyopathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoimmune Diseases; Benzimidazoles; Biph | 2005 |
An angiotensin II receptor antagonist reduces myocardial damage in an animal model of myocarditis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Body | 1994 |