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candesartan cilexetil and Myocardial Infarction

candesartan cilexetil has been researched along with Myocardial Infarction in 13 studies

candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
" The present study was conducted to examine the combined effects of a chronic ACEI, ramipril, and a chronic Ang II type 1 receptor blocker, TCV116, on rat CHF after myocardial infarction (MI)."7.73Combined effects of ramipril and angiotensin II receptor blocker TCV116 on rat congestive heart failure after myocardial infarction. ( Huang, YW; Tao, ZW; Xia, Q; Xu, QW, 2005)
"The purpose of this study was to examine the cardiac phenotype and remodeling after myocardial infarction and the effect of the angiotensin II type 1 (AT1) receptor antagonist (TCV-116) on the gene expression."7.69Inhibition by angiotensin II type 1 receptor antagonist of cardiac phenotypic modulation after myocardial infarction. ( Akioka, K; Hanatani, A; Iwao, H; Kim, S; Omura, T; Takeda, T; Takeuchi, K; Teragaki, M; Toda, I; Yoshiyama, M, 1995)
" The present study was conducted to examine the combined effects of a chronic ACEI, ramipril, and a chronic Ang II type 1 receptor blocker, TCV116, on rat CHF after myocardial infarction (MI)."3.73Combined effects of ramipril and angiotensin II receptor blocker TCV116 on rat congestive heart failure after myocardial infarction. ( Huang, YW; Tao, ZW; Xia, Q; Xu, QW, 2005)
"Because the effects of an aldosterone receptor antagonist on transcriptional factors and mRNA expression have not been fully examined in myocardial infarction (MI), the present study examined the effects of spironolactone (SPIRO) and candesartan cilexitil (CAN) on activation of activator protein-1 (AP-1), nuclear factor-kappaB (NF-kappaB) and mRNA expression in the non-ischemic myocardium after MI."3.72Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with myocardial infarction. ( Akioka, K; Iwao, H; Izumi, Y; Kim, S; Matsumoto, R; Nakamura, Y; Omura, T; Takeuchi, K; Yoshikawa, J; Yoshiyama, M, 2004)
"To investigate the long-term effects of TCV116 (candesartan cilexetil) on cardiac function changes after myocardial infarction."3.72[Long-term effects of TCV116 on cardiac function changes after myocardial infarction]. ( Tao, ZW; Wang, Y; Wang, YW, 2004)
"The aims were (1) to investigate the effect of hypertention on left ventricular dilatation and haemodynamic alterations following acute myocardial infarction in spontaneously hypertensive rats (SHR) and normotensive rats (WKY); (2) to compare haemodynamic indices between the two groups; (3) to assess whether the angiotensin II type 1 receptor antagonist (AIIA), TCV-116, prevented left ventricular dilatation after myocardial infarction; and (4) to compare the effect of AIIA with that of the angiotensin converting enzyme (ACE) inhibitor, delapril."3.69An angiotensin II receptor antagonist attenuates left ventricular dilatation after myocardial infarction in the hypertensive rat. ( Nishikimi, T; Takeda, T; Takeuchi, K; Yamagishi, H, 1995)
"The purpose of this study was to examine the cardiac phenotype and remodeling after myocardial infarction and the effect of the angiotensin II type 1 (AT1) receptor antagonist (TCV-116) on the gene expression."3.69Inhibition by angiotensin II type 1 receptor antagonist of cardiac phenotypic modulation after myocardial infarction. ( Akioka, K; Hanatani, A; Iwao, H; Kim, S; Omura, T; Takeda, T; Takeuchi, K; Teragaki, M; Toda, I; Yoshiyama, M, 1995)
"To investigate the contribution of the cardiac renin-angiotensin system to ventricular dilatation after myocardial infarction, we examined the effects of 3-week treatments with an angiotensin converting enzyme inhibitor, delapril, and a selective angiotensin II type 1 (AT1) receptor antagonist, TCV-116, on haemodynamics and ventricular angiotensin II contents in myocardial-infarcted rats."3.68Contribution of cardiac renin-angiotensin system to ventricular remodelling in myocardial-infarcted rats. ( Kim, S; Nishikimi, T; Takeda, T; Takeuchi, K; Yamagishi, H, 1993)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (53.85)18.2507
2000's6 (46.15)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumoto, R2
Yoshiyama, M4
Omura, T4
Kim, S4
Nakamura, Y1
Izumi, Y2
Akioka, K3
Iwao, H4
Takeuchi, K6
Yoshikawa, J3
Tao, ZW2
Wang, YW1
Wang, Y1
Huang, YW1
Xia, Q1
Xu, QW1
Kusuyama, T2
Nishiya, D1
Enomoto, S1
Suzuki, H2
Omori, Y1
Soda, T1
Tsunoda, F1
Sato, T1
Shoji, M1
Iso, Y1
Kondo, T1
Koba, S1
Geshi, E1
Katagiri, T1
Lange, SA1
Wolf, B1
Schober, K1
Wunderlich, C1
Marquetant, R1
Weinbrenner, C1
Strasser, RH1
Nishikimi, T2
Yamagishi, H2
Takeda, T3
Nio, Y2
Matsubara, H2
Murasawa, S2
Kanasaki, M1
Inada, M2
Hanatani, A2
Toda, I1
Teragaki, M1
Kijima, K1
Maruyama, K1
Mori, Y1
Nishizawa, M1
Kumagai, H1
Ichikawa, M1
Oshima, N1
Saruta, T1
Nakayama, K1

Other Studies

13 other studies available for candesartan cilexetil and Myocardial Infarction

ArticleYear
Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with myocardial infarction.
    Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:4

    Topics: Animals; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Collagen Type I; Collagen Ty

2004
[Long-term effects of TCV116 on cardiac function changes after myocardial infarction].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:6

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Heart Failure;

2004
Combined effects of ramipril and angiotensin II receptor blocker TCV116 on rat congestive heart failure after myocardial infarction.
    Chinese medical journal, 2005, Jan-20, Volume: 118, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressur

2005
Angiotensin blockade inhibits osteopontin expression in non-infarcted myocardium after myocardial infarction.
    Journal of pharmacological sciences, 2005, Volume: 98, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chemokine CCL2

2005
Inhibitory effect of candesartan cilexetil on left ventricular remodeling after myocardial infarction.
    International heart journal, 2006, Volume: 47, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2006
Chronic angiotensin II receptor blockade induces cardioprotection during ischemia by increased PKC-epsilon expression in the mouse heart.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting En

2007
An angiotensin II receptor antagonist attenuates left ventricular dilatation after myocardial infarction in the hypertensive rat.
    Cardiovascular research, 1995, Volume: 29, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomyopath

1995
Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarction.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:1

    Topics: Angiotensin Receptor Antagonists; Animals; Base Sequence; Benzimidazoles; Biphenyl Compounds; Blood

1995
Contribution of cardiac renin-angiotensin system to ventricular remodelling in myocardial-infarcted rats.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:11

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzym

1993
Inhibition by angiotensin II type 1 receptor antagonist of cardiac phenotypic modulation after myocardial infarction.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:9

    Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial N

1995
Regulation of gene transcription of angiotensin II receptor subtypes in the heart.
    Advances in experimental medicine and biology, 1996, Volume: 396

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body

1996
Improvement in baroreflex function by an oral angiotensin receptor antagonist in rats with myocardial infarction.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2

    Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex

1997
Angiotensin II type 1-receptor antagonist candesartan cilexitil prevents left ventricular dysfunction in myocardial infarcted rats.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:1

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Benzi

1998