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candesartan cilexetil and Diabetic Glomerulosclerosis

candesartan cilexetil has been researched along with Diabetic Glomerulosclerosis in 8 studies

candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects

Research Excerpts

ExcerptRelevanceReference
"The effect of the angiotensin II receptor blocker, candesartan cilexetil, on proteinuria was examined in a prospective, multicenter, randomized, double-blind study in Japanese subjects with type 2 diabetes."5.11Antiproteinuric effect of candesartan cilexetil in Japanese subjects with type 2 diabetes and nephropathy. ( Haneda, M; Kawamori, R; Kikkawa, R; Sakai, H, 2004)
"Fifty-two patients with type 2 diabetes with normo- and microalbuminuria participated in this study."2.71Low-dose candesartan cilexetil prevents early kidney damage in type 2 diabetic patients with mildly elevated blood pressure. ( Adachi, M; Hirano, T; Ikejiri, R; Murayama, S; Okada, K; Sakaue, T, 2003)
"Many patients with diabetic nephropathy (DN) have levels of albuminuria > 1 g/day and blood pressure >135/85 mmHg, despite antihypertensive combination therapy, including recommended doses of ACE inhibitors, e."2.70Dual blockade of the renin-angiotensin system in diabetic nephropathy: a randomized double-blind crossover study. ( Christensen, PK; Jensen, BR; Parving, HH; Rossing, K, 2002)
"It was launched in 1998 for the treatment of hypertension."2.45Candesartan: widening indications for this angiotensin II receptor blocker? ( Mendis, B; Page, SR, 2009)
"Many models of diabetic nephropathy have been reported."1.38A novel diabetes mellitus mouse model, MAFA-deficient and beta cell-specific MAFK-overexpressing hybrid transgenic mice, developed severe diabetic nephropathy and improved with TCV-116 (candesartan cilexetil) treatment. ( Fujita, A; Morito, N; Ojima, M; Okamura, M; Shimohata, H; Takahashi, S; Yamagata, K; Yoh, K, 2012)
"The pregnancy was terminated, and she delivered at 27 weeks' gestation."1.35Oligohydramnios and pulmonary hypoplasia: a case in which involvement of an angiotensin II receptor antagonist was suspected. ( Hirahara, F; Ishikawa, H; Kato, K; Okuda, M; Takahashi, T, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mendis, B1
Page, SR1
Fujita, A1
Yoh, K1
Shimohata, H1
Morito, N1
Ojima, M1
Okamura, M1
Takahashi, S1
Yamagata, K1
Murayama, S1
Hirano, T1
Sakaue, T1
Okada, K1
Ikejiri, R1
Adachi, M1
Kakizawa, H1
Itoh, Y1
Imamura, S1
Matsumoto, T1
Ishiwata, Y1
Ono, Y1
Yamamoto, K1
Kato, T1
Hayakawa, N1
Oda, N1
Goto, Y2
Nagasaka, A1
Senda, T1
Itoh, M1
Haneda, M1
Kikkawa, R1
Sakai, H1
Kawamori, R1
Kato, K1
Okuda, M1
Ishikawa, H1
Takahashi, T1
Hirahara, F1
Nakamura, T1
Ushiyama, C1
Suzuki, S1
Shimada, N1
Sekizuka, K1
Ebihara, I1
Takahashi, Y1
Tanaka, A1
Koide, H1
Rossing, K1
Christensen, PK1
Jensen, BR1
Parving, HH1

Reviews

1 review available for candesartan cilexetil and Diabetic Glomerulosclerosis

ArticleYear
Candesartan: widening indications for this angiotensin II receptor blocker?
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases

2009

Trials

4 trials available for candesartan cilexetil and Diabetic Glomerulosclerosis

ArticleYear
Low-dose candesartan cilexetil prevents early kidney damage in type 2 diabetic patients with mildly elevated blood pressure.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:6

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphe

2003
Antiproteinuric effect of candesartan cilexetil in Japanese subjects with type 2 diabetes and nephropathy.
    Diabetes research and clinical practice, 2004, Volume: 66, Issue:1

    Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Creatinine; Diabetes Mellitus,

2004
Comparison between the angiotensin II receptor antagonist candesartan cilexetil and the angiotensin-converting enzyme inhibitor trandolapril in microalbuminuria of patients with early diabetic nephropathy.
    Nephron, 2000, Volume: 86, Issue:2

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2000
Dual blockade of the renin-angiotensin system in diabetic nephropathy: a randomized double-blind crossover study.
    Diabetes care, 2002, Volume: 25, Issue:1

    Topics: Adrenergic beta-Antagonists; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

2002

Other Studies

3 other studies available for candesartan cilexetil and Diabetic Glomerulosclerosis

ArticleYear
A novel diabetes mellitus mouse model, MAFA-deficient and beta cell-specific MAFK-overexpressing hybrid transgenic mice, developed severe diabetic nephropathy and improved with TCV-116 (candesartan cilexetil) treatment.
    Experimental animals, 2012, Volume: 61, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphe

2012
Possible role of VEGF in the progression of kidney disease in streptozotocin (STZ)-induced diabetic rats: effects of an ACE inhibitor and an angiotensin II receptor antagonist.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:7

    Topics: Albuminuria; Analysis of Variance; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme I

2004
Oligohydramnios and pulmonary hypoplasia: a case in which involvement of an angiotensin II receptor antagonist was suspected.
    The journal of obstetrics and gynaecology research, 2008, Volume: 34, Issue:2

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Diabetic Nephrop

2008