candesartan cilexetil has been researched along with Chronic Kidney Failure in 3 studies
candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects
| Excerpt | Relevance | Reference |
|---|---|---|
| "Candesartan cilexetil (1 mg/kg/day) and enalapril (10 mg/kg/day) were orally administered once a day for 4 weeks (the short-term experiment) or 16 weeks (the long-term experiment) to 5/6 nephrectomized rats beginning 15 weeks after the nephrectomy, that is, after they had already showed marked proteinuria." | 3.70 | Effect of candesartan cilexetil (TCV-116) in rats with chronic renal failure. ( Fukuda, R; Imura, Y; Matsuo, T; Nagano, H; Naka, T; Nishikawa, K; Noda, M; Ohta, M; Shibouta, Y, 1999) |
| "In vehicle-treated rats, proteinuria, glomerulosclerosis, interstitial mononuclear cell (MNC) infiltration and interstitial fibrosis developed." | 1.30 | Effects of candesartan cilexetil (TCV-116) and enalapril in 5/6 nephrectomized rats. ( Fukuda, R; Imura, Y; Matsuo, T; Nagano, H; Nishikawa, K; Noda, M; Ohta, M; Shibouta, Y, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schulz, EG | 1 |
| Bahri, S | 1 |
| Schettler, V | 1 |
| Popov, AF | 1 |
| Hermann, M | 1 |
| Noda, M | 2 |
| Fukuda, R | 2 |
| Matsuo, T | 2 |
| Ohta, M | 2 |
| Nagano, H | 2 |
| Imura, Y | 2 |
| Nishikawa, K | 2 |
| Shibouta, Y | 2 |
| Naka, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Renal Protective Effect of ACEI and ARB in Primary Hyperoxaluria[NCT00280215] | Phase 3 | 0 participants (Actual) | Interventional | 2007-12-31 | Withdrawn (stopped due to Inadequate number of patients, lack of funding) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for candesartan cilexetil and Chronic Kidney Failure
| Article | Year |
|---|---|
Pharmacokinetics and antihypertensive effects of candesartan cilexetil in patients undergoing haemodialysis: an open-label, single-centre study.
Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hu | 2009 |
Effects of candesartan cilexetil (TCV-116) and enalapril in 5/6 nephrectomized rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 1997 |
Effect of candesartan cilexetil (TCV-116) in rats with chronic renal failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; | 1999 |