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candesartan cilexetil and Bright Disease

candesartan cilexetil has been researched along with Bright Disease in 8 studies

candesartan cilexetil: a prodrug which is metabolized to an active form candesartan to exert its biological effects

Bright Disease: A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright.

Research Excerpts

ExcerptRelevanceReference
"A prospective, randomised, double-blind, parallel-group, dose-response trial was conducted to investigate the antiproteinuric effect of candesartan cilexetil, the angiotensin II type 1 receptor blocker, in patients with chronic glomerulonephritis."9.10Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis. ( Abe, K; Arakawa, M; Kikkawa, R; Kurokawa, K; Ogawa, N; Onoyama, K; Saruta, T; Tomita, K; Ueda, N, 2002)
"To examine the role of the angiotensin II (ATII) type 1a receptor (AT1-R) pathway in renal tissue damage and repair, we investigated reversible glomerular injury in a mouse model of habu snake venom (HSV)-induced glomerulonephritis using AT1-R-deficient (AT1a-/-) mice and AT1-R antagonist-treated mice."7.78Glomerular repair retardation via blocking of angiotensin II type 1a receptor pathway in a mouse glomerulonephritis model. ( Abe, K; Abe, S; Furusu, A; Hayashi, W; Io, K; Kohno, S; Koji, T; Miyazaki, M; Nishino, T; Obata, Y; Sugaya, T, 2012)
"In this prospective, parallel, open study of 86 patients with CGN, we compared the effects on proteinuria and renal functions of 36 months with comparable blood pressure (BP) control achieved by candesartan cilexetil (candesartan, 4-12 mg/day) or benazepril hydrochrolide (benazepril, 2."5.13Dual blockade of the rennin-angiotensin system versus maximal recommended dose of angiotensin II receptor blockade in chronic glomerulonephritis. ( Fujiwara, H; Minatoguchi, S; Mori-Takeyama, U; Murata, I; Oda, H; Ohashi, H; Ohno, M; Ozaki, Y, 2008)
"A prospective, randomised, double-blind, parallel-group, dose-response trial was conducted to investigate the antiproteinuric effect of candesartan cilexetil, the angiotensin II type 1 receptor blocker, in patients with chronic glomerulonephritis."5.10Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis. ( Abe, K; Arakawa, M; Kikkawa, R; Kurokawa, K; Ogawa, N; Onoyama, K; Saruta, T; Tomita, K; Ueda, N, 2002)
"To examine the role of the angiotensin II (ATII) type 1a receptor (AT1-R) pathway in renal tissue damage and repair, we investigated reversible glomerular injury in a mouse model of habu snake venom (HSV)-induced glomerulonephritis using AT1-R-deficient (AT1a-/-) mice and AT1-R antagonist-treated mice."3.78Glomerular repair retardation via blocking of angiotensin II type 1a receptor pathway in a mouse glomerulonephritis model. ( Abe, K; Abe, S; Furusu, A; Hayashi, W; Io, K; Kohno, S; Koji, T; Miyazaki, M; Nishino, T; Obata, Y; Sugaya, T, 2012)
"Perindopril was stopped after the 8-week administration of the two drugs."1.32[Additive antiproteinuric effect of angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor in patients with chronic glomerulonephritis]. ( Amemiya, M; Ando, Y; Asano, Y; Honma, S; Iimura, O; Kusano, E; Muto, S; Tanba, K; Yanagiba, S, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, W1
Obata, Y1
Nishino, T1
Abe, S1
Io, K1
Furusu, A1
Abe, K2
Miyazaki, M1
Sugaya, T1
Koji, T1
Kohno, S1
Kurokawa, K1
Saruta, T1
Arakawa, M1
Kikkawa, R1
Ueda, N1
Onoyama, K1
Tomita, K1
Ogawa, N1
Iimura, O1
Kusano, E1
Tanba, K1
Yanagiba, S1
Amemiya, M1
Ando, Y1
Honma, S1
Muto, S1
Asano, Y1
Mori-Takeyama, U1
Minatoguchi, S1
Murata, I1
Fujiwara, H1
Ozaki, Y1
Ohno, M1
Oda, H1
Ohashi, H1
Yayama, K2
Makino, J1
Takano, M2
Okamoto, H2
Matsui, T1
Hayashi, K1
Nagamatsu, T1
Suzuki, Y2
Shibouta, Y1
Chatani, F1
Ishimura, Y1
Sanada, T1
Ohta, M1
Inada, Y1
Nishikawa, K1
Shirato, I1
Okumura, K1
Ravetch, JV1
Takai, T1
Tomino, Y1
Ra, C1

Trials

2 trials available for candesartan cilexetil and Bright Disease

ArticleYear
Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2002, Volume: 3, Issue:3

    Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds

2002
Dual blockade of the rennin-angiotensin system versus maximal recommended dose of angiotensin II receptor blockade in chronic glomerulonephritis.
    Clinical and experimental nephrology, 2008, Volume: 12, Issue:1

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Benzazepines; Benzimidazoles; Biphenyl Compounds; Bl

2008

Other Studies

6 other studies available for candesartan cilexetil and Bright Disease

ArticleYear
Glomerular repair retardation via blocking of angiotensin II type 1a receptor pathway in a mouse glomerulonephritis model.
    Nephron. Experimental nephrology, 2012, Volume: 122, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds

2012
[Additive antiproteinuric effect of angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor in patients with chronic glomerulonephritis].
    Nihon Jinzo Gakkai shi, 2003, Volume: 45, Issue:5

    Topics: Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2003
Role of angiotensin II in the transforming growth factor-beta 1 expression of rat kidney in anti-glomerular basement membrane antiserum-induced glomerulonephritis.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Basement Membrane; Benzimidazoles; Biphen

1995
Activation of the renin-angiotensin system in anti-glomerular basement membrane antibody-induced glomerulonephritis.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:3

    Topics: Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antibodies; Basement Membrane; Benzimida

1995
TCV-116 inhibits renal interstitial and glomerular injury in glomerulosclerotic rats.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl

1996
Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis.
    Kidney international, 1998, Volume: 54, Issue:4

    Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Basement Membrane; Benzimidazoles

1998