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candesartan and Weight Reduction

candesartan has been researched along with Weight Reduction in 2 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"We investigated the change in weight over 6 months in 6933 patients in the Candesartan in Heart failure: Reduction in Mortality and morbidity (CHARM) programme, and its association with subsequent mortality (1435 deaths) over a median 32."9.13Weight loss and mortality risk in patients with chronic heart failure in the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) programme. ( Anker, SD; Dobson, J; Granger, CB; McMurray, JJ; Michelson, EL; Ostergren, J; Pfeffer, MA; Pocock, SJ; Solomon, SD; Swedberg, KB; Yusuf, S, 2008)
" The aim of this study was to investigate whether weight reduction after AT(1)-blockade is dependent on dose, blood pressure reduction and leptin signalling."7.77Weight loss and hypophagia after high-dose AT1-blockade is only observed after high dosing and depends on regular leptin signalling but not blood pressure. ( Jöhren, O; Markert, A; Müller-Fielitz, H; Pahlke, F; Raasch, W; Wittmershaus, C, 2011)
"We investigated the change in weight over 6 months in 6933 patients in the Candesartan in Heart failure: Reduction in Mortality and morbidity (CHARM) programme, and its association with subsequent mortality (1435 deaths) over a median 32."5.13Weight loss and mortality risk in patients with chronic heart failure in the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) programme. ( Anker, SD; Dobson, J; Granger, CB; McMurray, JJ; Michelson, EL; Ostergren, J; Pfeffer, MA; Pocock, SJ; Solomon, SD; Swedberg, KB; Yusuf, S, 2008)
" The aim of this study was to investigate whether weight reduction after AT(1)-blockade is dependent on dose, blood pressure reduction and leptin signalling."3.77Weight loss and hypophagia after high-dose AT1-blockade is only observed after high dosing and depends on regular leptin signalling but not blood pressure. ( Jöhren, O; Markert, A; Müller-Fielitz, H; Pahlke, F; Raasch, W; Wittmershaus, C, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pocock, SJ1
McMurray, JJ1
Dobson, J1
Yusuf, S1
Granger, CB1
Michelson, EL1
Ostergren, J1
Pfeffer, MA1
Solomon, SD1
Anker, SD1
Swedberg, KB1
Müller-Fielitz, H1
Markert, A1
Wittmershaus, C1
Pahlke, F1
Jöhren, O1
Raasch, W1

Trials

1 trial available for candesartan and Weight Reduction

ArticleYear
Weight loss and mortality risk in patients with chronic heart failure in the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) programme.
    European heart journal, 2008, Volume: 29, Issue:21

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphe

2008

Other Studies

1 other study available for candesartan and Weight Reduction

ArticleYear
Weight loss and hypophagia after high-dose AT1-blockade is only observed after high dosing and depends on regular leptin signalling but not blood pressure.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure

2011