candesartan has been researched along with Rupture, Spontaneous in 1 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Candesartan has a preventive value against atherosclerotic plaque rupture in hypercholesterolemic rabbits, likely through its reduction of MMP-9 expression, inhibition of macrophage accumulation and increase of collagen content within the plaques." | 1.36 | [Prevention of rupture of atherosclerotic plaque by Candesartan in rabbit model]. ( Li, SA; Meng, ZM; Qian, HD; Shen, L; Wu, AS; Yin, HC; Yu, T; Zhou, XF; Zhu, WL, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, XF | 1 |
| Yin, HC | 1 |
| Zhu, WL | 1 |
| Shen, L | 1 |
| Yu, T | 1 |
| Li, SA | 1 |
| Meng, ZM | 1 |
| Wu, AS | 1 |
| Qian, HD | 1 |
1 other study available for candesartan and Rupture, Spontaneous
| Article | Year |
|---|---|
[Prevention of rupture of atherosclerotic plaque by Candesartan in rabbit model].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Abdominal; Benzimi | 2010 |