Page last updated: 2024-10-24

candesartan and Proteinuria

candesartan has been researched along with Proteinuria in 52 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"We sought to compare the effect of manidipine versus hydrochlorothiazide (HCTZ) in addition to candesartan on the urinary albumin excretion rate (UAER) in hypertensive patients with type II diabetes and microalbuminuria."9.12Addition of manidipine improves the antiproteinuric effect of candesartan in hypertensive patients with type II diabetes and microalbuminuria. ( Corradi, L; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2007)
" We used enalapril, an angiotensin-converting enzyme inhibitor (ACEI) and candesartan, an angiotensin II receptor blocker (ARB), for the control of proteinuria in a case of immunosuppressive treatment (IST)-resistant nephrotic syndrome."7.73Treatment with candesartan combined with angiotensin-converting enzyme inhibitor for immunosuppressive treatment-resistant nephrotic syndrome after allogeneic stem cell transplantation. ( Hosoi, G; Ikemiya, M; Ishii, T; Noma, H; Osugi, Y; Sako, M; Yamada, H, 2006)
"Azilsartan is a strong antihypertensive ARB, but its antiproteinuric effects are not well understood."7.01Stronger Effect of Azilsartan on Reduction of Proteinuria Compared to Candesartan in Patients with CKD: A Randomized Crossover Trial. ( Eriguchi, M; Fujisaki, K; Kitazono, T; Nakano, T; Suehiro, T; Tanaka, S; Torisu, K; Tsuchimoto, A; Tsujikawa, H; Tsuruya, K; Yamada, S; Yoshida, H, 2021)
" Beginning 8 wk after birth, SHR underwent unilateral nephrectomy and were given vehicle (control), or candesartan at a standard 5 mg/kg per d (T5), high 25 mg/kg per d (T25), or ultrahigh 75 mg/kg per d dosage (T75)."5.34Long-term, high-dosage candesartan suppresses inflammation and injury in chronic kidney disease: nonhemodynamic renal protection. ( Dworkin, LD; Gong, R; Rifai, A; Tolbert, EM; Yu, C, 2007)
"The reduction in proteinuria induced by lisinopril (11."5.14[The antiproteinuric effect of the blockage of the renin-angiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? ]. ( Gutiérrez Solís, E; Gutiérrez, E; Huerta, A; Morales, E; Praga, M; Segura, J, 2009)
"We sought to compare the effect of manidipine versus hydrochlorothiazide (HCTZ) in addition to candesartan on the urinary albumin excretion rate (UAER) in hypertensive patients with type II diabetes and microalbuminuria."5.12Addition of manidipine improves the antiproteinuric effect of candesartan in hypertensive patients with type II diabetes and microalbuminuria. ( Corradi, L; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2007)
"The renoprotective effect of candesartan is considered more favorable than amlodipine in the treatment of ADPKD."5.11Calcium channel blocker versus angiotensin II receptor blocker in autosomal dominant polycystic kidney disease. ( Higaki, Y; Higashihara, E; Horie, S; Hosoya, T; Kamura, K; Mochizuki, T; Nakayama, T; Nutahara, K; Shimizu, T; Tsuchiya, K; Yamamoto, N, 2005)
"Candesartan promotes a complementary antiproteinuric and a small antihypertensive effect after a treatment period of 8 weeks in patients with chronic glomerulonephritis when given in conjunction with an ACEI."5.10Reduction of proteinuria; combined effects of receptor blockade and low dose angiotensin-converting enzyme inhibition. ( Bader, BD; Berger, ED; Ebert, C; Erley, CM; Risler, T, 2002)
"In a private consulting practice setting, the addition of 8 mg of Candesartan in normotensive patients with chronic renal disease and proteinuria receiving an ACEI reduced proteinuria and blood pressure."5.10Randomized controlled crossover study of the effect on proteinuria and blood pressure of adding an angiotensin II receptor antagonist to an angiotensin converting enzyme inhibitor in normotensive patients with chronic renal disease and proteinuria. ( Fairley, K; Kincaid-Smith, P; Packham, D, 2002)
" After 16 weeks, they were randomized into 4 groups (n = 10 each) with comparable proteinuria: (1) control group sacrificed immediately for baseline data, and groups gavaged daily for 8 weeks with (2) placebo, (3) perindopril (1 mg/kg/day), or (4) candesartan (10 mg/kg/day)."3.75Functional and partial morphological regression of established renal injury in the obese zucker rat by blockade of the renin-angiotensin system. ( Amann, K; Boor, P; Heidland, A; Lill, M; Sebeková, K, 2009)
" We subsequently used full dose ramipril, candesartan and aliskiren under a close monitoring of kidney function and electrolytes and examined the effect on proteinuria, clinical course and tolerability over 12 months."3.75Effect of a triple blockade of the renin-angiotensin-system in recurrent focal segmental glomerulosclerosis after kidney transplantation. ( Amann, K; Frank, H; Freiberger, V; Heemann, U, 2009)
"Candesartan doses in excess of the recommended antihypertensive maxima have been reported to lead to greater reductions of proteinuria than the advised doses."3.75Proteinuria: Increased angiotensin-receptor blocking is not the first option. ( Cravedi, P; Remuzzi, G; Ruggenenti, P, 2009)
" We used enalapril, an angiotensin-converting enzyme inhibitor (ACEI) and candesartan, an angiotensin II receptor blocker (ARB), for the control of proteinuria in a case of immunosuppressive treatment (IST)-resistant nephrotic syndrome."3.73Treatment with candesartan combined with angiotensin-converting enzyme inhibitor for immunosuppressive treatment-resistant nephrotic syndrome after allogeneic stem cell transplantation. ( Hosoi, G; Ikemiya, M; Ishii, T; Noma, H; Osugi, Y; Sako, M; Yamada, H, 2006)
"Standard ACEI plus candesartan is more effective in reducing systolic blood pressure and proteinuria than a 50% increase in ACEI dose."3.72Dual blockade of the renin-angiotensin system compared with a 50% increase in the dose of angiotensin-converting enzyme inhibitor: effects on proteinuria and blood pressure. ( Fairley, KF; Kincaid-Smith, P; Packham, D, 2004)
"Time-dependent elevation of MCP-1 expression was dramatically suppressed by treatment with the angiotensin-converting enzyme inhibitor enalapril or the AT1 receptor antagonist candesartan, and was closely associated with effects on proteinuria and glomerular macrophage number."3.70Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats. ( Brenner, BM; Kato, S; Lee, KW; Luyckx, VA; MacKenzie, HS; Ots, M; Troy, JL; Ziai, F, 1999)
"Azilsartan is a strong antihypertensive ARB, but its antiproteinuric effects are not well understood."3.01Stronger Effect of Azilsartan on Reduction of Proteinuria Compared to Candesartan in Patients with CKD: A Randomized Crossover Trial. ( Eriguchi, M; Fujisaki, K; Kitazono, T; Nakano, T; Suehiro, T; Tanaka, S; Torisu, K; Tsuchimoto, A; Tsujikawa, H; Tsuruya, K; Yamada, S; Yoshida, H, 2021)
" The authors randomly assigned 269 patients who had persistent proteinuria (> or =1 g/d) despite 7 wk of treatment with the highest approved dosage of candesartan (16 mg/d) to 16, 64, or 128 mg/d candesartan for 30 wk."2.74Supramaximal dose of candesartan in proteinuric renal disease. ( Burgess, E; Chiu, A; Muirhead, N; Pichette, V; Rene de Cotret, P; Tobe, S, 2009)
"After the double-blind treatment phase, proteinuria was reduced to 1."2.71Additional antiproteinuric effect of ultrahigh dose candesartan: a double-blind, randomized, prospective study. ( Delles, C; Fleischmann, EH; Klingbeil, AU; Schmieder, RE; Veelken, R, 2005)
"Proteinuria is common following kidney transplantation and affects more than 40% of kidney transplant patients per year."2.47Causes and consequences of proteinuria following kidney transplantation. ( G-Cosío, F; Suárez Fernández, ML, 2011)
"Candesartan cilexetil was considered to be safe even for long-term treatment in renal transplant patients, and effective to protect renal graft function."1.38Long-term renoprotective effect of candesartan in renal transplant patients. ( Hayashi, T; Ishii, T; Itami, Y; Nishioka, T; Nose, K; Uemura, H; Yasuda, M, 2012)
"The regular dose of an angiotensin II type-1 receptor blocker (ARB) in renal transplant patients for hypertension is shown to be safe and effective; however, information on the appropriate dosing of ARBs in renal transplant patients is limited."1.37Safety and efficacy of administering the maximal dose of candesartan in renal transplant recipients. ( Abe, T; Ichimaru, N; Imamura, R; Isaka, Y; Kawada, N; Kitamura, H; Kojima, Y; Kokado, Y; Moriyama, T; Nonomura, N; Okumi, M; Rakugi, H; Takahara, S, 2011)
"Gross proteinuria was largely unaffected by (AT1R) blockade and renal function further declined necessitating, initiation of hemodialysis."1.36Gross proteinuria and subacute renal failure after coronary angiography - a case report of cholesterol crystal embolization. ( Biesenbach, P; Gremmel, T; Hörl, WH; Kain, R; Säemann, MD, 2010)
" Beginning 8 wk after birth, SHR underwent unilateral nephrectomy and were given vehicle (control), or candesartan at a standard 5 mg/kg per d (T5), high 25 mg/kg per d (T25), or ultrahigh 75 mg/kg per d dosage (T75)."1.34Long-term, high-dosage candesartan suppresses inflammation and injury in chronic kidney disease: nonhemodynamic renal protection. ( Dworkin, LD; Gong, R; Rifai, A; Tolbert, EM; Yu, C, 2007)
"Recent immunosuppressive treatments for lupus nephritis have improved renal survival rate, however, there still exists lupus nephritis refractory to these treatments."1.33Antiproteinuric effect of ARB in lupus nephritis patients with persistent proteinuria despite immunosuppressive therapy. ( Kanda, H; Kubo, K; Mimura, T; Sato, K; Tateishi, S; Yamamoto, K; Yonezumi, A, 2005)
"We report here a case of type I diabetes mellitus with secondary FGS accompanied by proteinuria 10 months following kidney transplantation."1.33Secondary focal segmental glomerulosclerosis following kidney transplantation in a patient with type I diabetes mellitus. ( Hosoya, T; Mitome, J; Miyazaki, Y; Tanno, Y; Utsunomiya, Y; Yamaguchi, Y; Yamamoto, H; Yamamoto, I, 2006)
"Early proteinuric diabetic nephropathy increases renal expression of the p47phox component of NAD(P)H oxidase and eNOS with increased indices of systemic and renal oxidative/nitrosative stress."1.31Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB. ( Fujita, T; Goto, A; Onozato, ML; Tojo, A; Wilcox, CS, 2002)
"Candesartan treatment ameliorated the glomerular morphological findings at six weeks after disease induction."1.31Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. ( Gejyo, F; Ikezumi, Y; Ito, Y; Kawachi, H; Koike, H; Morioka, Y; Nakamura, T; Nakatsue, T; Natori, Y; Oyanagi, A; Shimizu, F, 2002)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (9.62)18.2507
2000's40 (76.92)29.6817
2010's6 (11.54)24.3611
2020's1 (1.92)2.80

Authors

AuthorsStudies
Suehiro, T1
Tsuruya, K1
Yoshida, H1
Tsujikawa, H1
Yamada, S1
Tanaka, S1
Tsuchimoto, A1
Eriguchi, M1
Fujisaki, K1
Torisu, K1
Nakano, T1
Kitazono, T1
de Seigneux, S1
Courbebaisse, M1
Rutkowski, JM1
Wilhelm-Bals, A1
Metzger, M1
Khodo, SN1
Hasler, U1
Chehade, H1
Dizin, E1
Daryadel, A1
Stengel, B1
Girardin, E1
Prié, D1
Wagner, CA1
Scherer, PE1
Martin, PY1
Houillier, P1
Feraille, E1
Sebeková, K1
Lill, M1
Boor, P1
Heidland, A1
Amann, K2
Burgess, E1
Muirhead, N1
Rene de Cotret, P1
Chiu, A1
Pichette, V1
Tobe, S1
de Zeeuw, D1
Lambers-Heerspink, H1
Robles, NR1
Fernandez Carbonero, E1
Romero, B1
Sánchez Casado, E1
Cubero, JJ1
Freiberger, V1
Heemann, U4
Frank, H1
Ruggenenti, P1
Cravedi, P1
Remuzzi, G2
Morales, E1
Huerta, A1
Gutiérrez, E1
Gutiérrez Solís, E1
Segura, J1
Praga, M1
Biesenbach, P1
Gremmel, T1
Hörl, WH1
Kain, R1
Säemann, MD1
Suárez Fernández, ML1
G-Cosío, F1
Schmaderer, C2
Xing, CJ1
Anderson, G1
Hermans, R1
Lutz, J2
Baumann, M1
Okumi, M1
Kawada, N1
Ichimaru, N1
Kitamura, H1
Abe, T1
Imamura, R1
Kojima, Y1
Kokado, Y1
Isaka, Y1
Rakugi, H2
Nonomura, N1
Moriyama, T1
Takahara, S1
Ishii, T2
Yasuda, M1
Itami, Y1
Hayashi, T1
Uemura, H1
Nose, K1
Nishioka, T1
Luño, J1
Barrio, V1
Goicoechea, MA1
González, C1
de Vinuesa, SG1
Gómez, F1
Bernis, C1
Espinosa, M1
Ahijado, F1
Gómez, J1
Escalada, P1
Kuriyama, S1
Tomonari, H1
Tokudome, G1
Horiguchi, M1
Hayashi, H1
Kobayashi, H1
Ishikawa, M1
Hosoya, T3
Yokota, K1
Kishida, M1
Ogura, T1
Suzuki, J1
Otsuka, F1
Mimura, Y1
Takeda, M1
Nakamura, Y1
Makino, H1
Hollenberg, NK1
Zhou, MS1
Adam, AG1
Jaimes, EA1
Raij, L1
Tamura, K2
Umemura, M1
Yano, H1
Sakai, M1
Sakurai, Y2
Tsurumi, Y1
Koide, Y1
Usui, T1
Yabana, M1
Toya, Y1
Tokita, Y1
Umemura, S1
Song, JH1
Lee, SW1
Suh, JH1
Kim, ES1
Hong, SB1
Kim, KA1
Kim, MJ1
Matsuda, H1
Hayashi, K1
Homma, K1
Yoshioka, K1
Kanda, T1
Takamatsu, I1
Tatematsu, S1
Wakino, S1
Saruta, T2
Kumagai, H1
Onami, T1
Takimoto, C1
Iigaya, K1
Kincaid-Smith, P2
Fairley, KF1
Packham, D2
Nutahara, K1
Higashihara, E1
Horie, S1
Kamura, K1
Tsuchiya, K1
Mochizuki, T1
Nakayama, T1
Yamamoto, N1
Higaki, Y1
Shimizu, T1
Chang, A1
Logar, CM1
Finn, LS1
Alpers, CE1
Seliger, SL1
Kanda, H1
Kubo, K1
Tateishi, S1
Sato, K1
Yonezumi, A1
Yamamoto, K1
Mimura, T1
Schmieder, RE2
Klingbeil, AU1
Fleischmann, EH1
Veelken, R1
Delles, C1
Benigni, A1
Zoja, C1
Tomasoni, S1
Campana, M1
Corna, D1
Zanchi, C1
Gagliardini, E1
Garofano, E1
Rottoli, D1
Ito, T1
Osugi, Y1
Yamada, H1
Hosoi, G1
Noma, H1
Ikemiya, M1
Sako, M1
Yamamoto, I1
Yamamoto, H1
Mitome, J1
Tanno, Y1
Utsunomiya, Y1
Miyazaki, Y1
Yamaguchi, Y1
Risch, K1
Liu, S1
Antus, B1
Roos, M1
Ouyang, N1
Lehmann, M1
Vanecková, I1
Kopkan, L1
Husková, Z1
Vanourková, Z1
Schejbalová, S1
Cervenka, L1
Kramer, HJ1
Yu, C1
Gong, R1
Rifai, A1
Tolbert, EM1
Dworkin, LD1
Chandar, J1
Abitbol, C1
Montané, B1
Zilleruelo, G1
Omasu, F1
Oda, T1
Yamada, M1
Yoshizawa, N1
Yamakami, K1
Miura, S1
Kanno, Y1
Takenaka, T1
Nakamura, T4
Suzuki, H1
Fogari, R1
Corradi, L1
Zoppi, A1
Lazzari, P1
Mugellini, A1
Preti, P1
Rinaldi, A1
Bramlage, P1
Thoenes, M1
Paar, WD1
Bramlage, CP1
Krämer, S1
Kron, S1
Wang-Rosenke, Y1
Loof, T1
Khadzhynov, D1
Morgera, S1
Kawachi, H3
Shimizu, F3
Martini, S1
Neumayer, HH1
Peters, H1
Ohishi, M1
Takagi, T1
Ito, N1
Tatara, Y1
Hayashi, N1
Shiota, A1
Iwamoto, Y1
Katsuya, T1
Ogihara, T1
Honma, H1
Ikeda, Y1
Kuroyanagi, R1
Takano, H1
Obata, J2
Sato, T1
Kimura, H2
Yoshida, Y2
Hamar, P1
Peti-Peterdi, J1
Rázga, Z1
Kovács, G1
Rosivall, L1
Ohno, S1
Kurokawa, K1
Kato, S1
Luyckx, VA1
Ots, M1
Lee, KW1
Ziai, F1
Troy, JL2
Brenner, BM2
MacKenzie, HS2
Taal, MW1
Chertow, GM1
Rennke, HG1
Gurnani, A1
Jiang, T1
Shahsafaei, A1
Onozato, ML1
Tojo, A1
Goto, A1
Fujita, T1
Wilcox, CS1
Thurston, H1
Berger, ED1
Bader, BD1
Ebert, C1
Risler, T1
Erley, CM1
Fairley, K1
Ito, Y1
Morioka, Y1
Nakatsue, T1
Koike, H1
Ikezumi, Y1
Oyanagi, A1
Natori, Y2
Gejyo, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Randomised, Dose Ranging, Multi-Centre, Phase IIIb Study to Evaluate the Efficacy and Safety of High Doses of Candesartan Cilexetil (Atacand®) on the Reduction of Proteinuria in the Treatment of Subjects With Hypertension and Moderate to S[NCT00242346]Phase 3270 participants Interventional2003-04-30Completed
Phase IV Open Label Uncontrolled Trial of the Dual Blockade of the Renin Angiotensin System With Enalapril Plus Valsartan Combined With Oral Methylprednisolone for the Treatment of Proteinuria in IGA Nephropathy[NCT00367562]Phase 420 participants Interventional1996-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for candesartan and Proteinuria

ArticleYear
Causes and consequences of proteinuria following kidney transplantation.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:4

    Topics: Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Endothelium, Vascular; Graft Rejection;

2011
[Organ protection by angiotensin II receptor blockers].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals;

2004
Dual angiotensin II blockade: a promise of enhanced renal protection?
    Journal of hypertension, 2002, Volume: 20, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihype

2002

Trials

16 trials available for candesartan and Proteinuria

ArticleYear
Stronger Effect of Azilsartan on Reduction of Proteinuria Compared to Candesartan in Patients with CKD: A Randomized Crossover Trial.
    Kidney & blood pressure research, 2021, Volume: 46, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Antineoplastic Combined Chemotherapy Protocols; Benzimidazo

2021
Supramaximal dose of candesartan in proteinuric renal disease.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetic N

2009
Long-term antiproteinuric effect of dual renin-angiotensin system blockade.
    Cardiovascular therapeutics, 2009,Summer, Volume: 27, Issue:2

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benz

2009
[The antiproteinuric effect of the blockage of the renin-angiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? ].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009, Volume: 29, Issue:5

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benz

2009
Effects of dual blockade of the renin-angiotensin system in primary proteinuric nephropathies.
    Kidney international. Supplement, 2002, Issue:82

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti

2002
Antiproteinuric effects of combined antihypertensive therapies in patients with overt type 2 diabetic nephropathy.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:6

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihy

2002
Reduction of proteinuria; combined effects of receptor blockade and low dose angiotensin-converting enzyme inhibition.
    Current hypertension reports, 2003, Volume: 5, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents;

2003
The effects of dual blockade of the renin-angiotensin system on urinary protein and transforming growth factor-beta excretion in 2 groups of patients with IgA and diabetic nephropathy.
    Clinical nephrology, 2003, Volume: 60, Issue:5

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidaz

2003
Differing anti-proteinuric action of candesartan and losartan in chronic renal disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:11

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidaz

2003
Calcium channel blocker versus angiotensin II receptor blocker in autosomal dominant polycystic kidney disease.
    Nephron. Clinical practice, 2005, Volume: 99, Issue:1

    Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphe

2005
Additional antiproteinuric effect of ultrahigh dose candesartan: a double-blind, randomized, prospective study.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:10

    Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds

2005
Add-on angiotensin receptor blocker in patients who have proteinuric chronic kidney diseases and are treated with angiotensin-converting enzyme inhibitors.
    Clinical journal of the American Society of Nephrology : CJASN, 2006, Volume: 1, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2006
Addition of manidipine improves the antiproteinuric effect of candesartan in hypertensive patients with type II diabetes and microalbuminuria.
    American journal of hypertension, 2007, Volume: 20, Issue:10

    Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compound

2007
Renal protective effect in hypertensive patients: the high doses of angiotensin II receptor blocker (HARB) study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:12

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Com

2007
Reduction of proteinuria; combined effects of receptor blockade and low dose angiotensin-converting enzyme inhibition.
    Journal of hypertension, 2002, Volume: 20, Issue:4

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2002
Randomized controlled crossover study of the effect on proteinuria and blood pressure of adding an angiotensin II receptor antagonist to an angiotensin converting enzyme inhibitor in normotensive patients with chronic renal disease and proteinuria.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:4

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazo

2002

Other Studies

33 other studies available for candesartan and Proteinuria

ArticleYear
Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling.
    Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:7

    Topics: Adult; Albuminuria; Analysis of Variance; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Wes

2015
Functional and partial morphological regression of established renal injury in the obese zucker rat by blockade of the renin-angiotensin system.
    American journal of nephrology, 2009, Volume: 29, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimid

2009
Drug dosing for renoprotection: maybe it's time for a drug efficacy-safety score?
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

2009
Effect of a triple blockade of the renin-angiotensin-system in recurrent focal segmental glomerulosclerosis after kidney transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2009, Volume: 22, Issue:11

    Topics: Adult; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; An

2009
Proteinuria: Increased angiotensin-receptor blocking is not the first option.
    Nature reviews. Nephrology, 2009, Volume: 5, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2009
Gross proteinuria and subacute renal failure after coronary angiography - a case report of cholesterol crystal embolization.
    Wiener klinische Wochenschrift, 2010, Volume: 122, Issue:7-8

    Topics: Acute Kidney Injury; Angiotensin II Type 1 Receptor Blockers; Austria; Benzimidazoles; Biopsy; Biphe

2010
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
    Life sciences, 2011, Sep-12, Volume: 89, Issue:11-12

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiotonic Ag

2011
Safety and efficacy of administering the maximal dose of candesartan in renal transplant recipients.
    Clinical and experimental nephrology, 2011, Volume: 15, Issue:6

    Topics: Adult; Aged; Albuminuria; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Benzimidazo

2011
Long-term renoprotective effect of candesartan in renal transplant patients.
    Transplantation proceedings, 2012, Volume: 44, Issue:3

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pres

2012
Role of bradykinin in renoprotective effects by angiotensin II type 1 receptor antagonist in salt-sensitive hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl

2003
In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Co

2003
Acute renal failure due to cholesterol crystal embolism treated with LDL apheresis followed by corticosteroid and candesartan.
    Clinical and experimental nephrology, 2003, Volume: 7, Issue:1

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimi

2003
Dual blockade of the renin-angiotensin system compared with a 50% increase in the dose of angiotensin-converting enzyme inhibitor: effects on proteinuria and blood pressure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2004
A rare cause of necrotizing and crescentic glomerulonephritis in a young adult male.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:5

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Autoa

2005
Antiproteinuric effect of ARB in lupus nephritis patients with persistent proteinuria despite immunosuppressive therapy.
    Lupus, 2005, Volume: 14, Issue:4

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pres

2005
Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Gene Expression Regul

2006
Treatment with candesartan combined with angiotensin-converting enzyme inhibitor for immunosuppressive treatment-resistant nephrotic syndrome after allogeneic stem cell transplantation.
    International journal of hematology, 2006, Volume: 83, Issue:5

    Topics: Adolescent; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphe

2006
Secondary focal segmental glomerulosclerosis following kidney transplantation in a patient with type I diabetes mellitus.
    Clinical transplantation, 2006, Volume: 20 Suppl 15

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidaz

2006
Angiotensin type 1 and type 2 receptor blockade in chronic allograft nephropathy.
    Kidney international, 2006, Volume: 70, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Chronic Di

2006
Long-term prevention of hypertension and end-organ damage in Ren-2 transgenic rats is achieved only with persistent but not transient AT1 receptor blockade.
    Kidney & blood pressure research, 2007, Volume: 30, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Bip

2007
Long-term, high-dosage candesartan suppresses inflammation and injury in chronic kidney disease: nonhemodynamic renal protection.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure

2007
Angiotensin blockade as sole treatment for proteinuric kidney disease in children.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:5

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angio

2007
Effects of pioglitazone and candesartan on renal fibrosis and the intrarenal plasmin cascade in spontaneously hypercholesterolemic rats.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Disease Models

2007
[Albuminuria: an indicator of cardiovascular risk].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Oct-15, Volume: 102, Issue:10

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Anticholesteremic Agents; Antihypertensi

2007
Rosuvastatin is additive to high-dose candesartan in slowing progression of experimental mesangioproliferative glomerulosclerosis.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:4

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Disease Progression; Drug Thera

2008
Renal protective effects of angiotensin II receptor I antagonist CV-11974 in spontaneously hypertensive stroke-prone rats (SHR-sp).
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cereb

1994
Coinhibition of immune and renin-angiotensin systems reduces the pace of glomerulosclerosis in the rat remnant kidney.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10 Suppl 11

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cholesterol; D

1999
Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis.
    Kidney international, 1999, Volume: 55, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals;

1999
Effects of candesartan on the proteinuria of chronic glomerulonephritis.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arterioles; Benzimidazoles;

1999
Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats.
    Kidney international, 1999, Volume: 56, Issue:3

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence;

1999
Mechanisms underlying renoprotection during renin-angiotensin system blockade.
    American journal of physiology. Renal physiology, 2001, Volume: 280, Issue:2

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2

2001
Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB.
    Kidney international, 2002, Volume: 61, Issue:1

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; An

2002
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis.
    Kidney international, 2002, Volume: 61, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Chemok

2002