candesartan has been researched along with Parkinson Disease in 4 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Kulisevsky, J | 1 |
Martínez-Horta, S | 1 |
Campolongo, A | 1 |
Pascual-Sedano, B | 1 |
Marín-Lahoz, J | 1 |
Bejr-Kasem, H | 1 |
Labandeira-Garcia, JL | 4 |
Lanciego, JL | 2 |
Puig-Davi, A | 1 |
Horta-Barba, A | 1 |
Pagonabarraga, J | 1 |
Rodríguez-Antigüedad, J | 1 |
Muñoz, A | 1 |
Garrido-Gil, P | 1 |
Dominguez-Meijide, A | 1 |
Rodriguez-Perez, AI | 2 |
Valenzuela, R | 2 |
Villar-Cheda, B | 2 |
Guerra, MJ | 2 |
1 trial available for candesartan and Parkinson Disease
Article | Year |
---|---|
A randomized clinical trial of candesartan for cognitive impairment in Parkinson's disease.
Topics: Benzimidazoles; Cognition Disorders; Cognitive Dysfunction; Humans; Neuropsychological Tests; Parkin | 2023 |
3 other studies available for candesartan and Parkinson Disease
Article | Year |
---|---|
Angiotensin type 1 receptor blockage reduces l-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of vascular endothelial growth factor and interleukin-1β.
Topics: Adrenergic Agents; Angiotensin II Type 1 Receptor Blockers; Animals; Antiparkinson Agents; Benzimida | 2014 |
Estrogen and angiotensin interaction in the substantia nigra. Relevance to postmenopausal Parkinson's disease.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cell Death; Dopamine; Estradiol; Estrog | 2010 |
Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Co | 2012 |