Page last updated: 2024-10-24

candesartan and Parkinson Disease

candesartan has been researched along with Parkinson Disease in 4 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Kulisevsky, J1
Martínez-Horta, S1
Campolongo, A1
Pascual-Sedano, B1
Marín-Lahoz, J1
Bejr-Kasem, H1
Labandeira-Garcia, JL4
Lanciego, JL2
Puig-Davi, A1
Horta-Barba, A1
Pagonabarraga, J1
Rodríguez-Antigüedad, J1
Muñoz, A1
Garrido-Gil, P1
Dominguez-Meijide, A1
Rodriguez-Perez, AI2
Valenzuela, R2
Villar-Cheda, B2
Guerra, MJ2

Trials

1 trial available for candesartan and Parkinson Disease

ArticleYear
A randomized clinical trial of candesartan for cognitive impairment in Parkinson's disease.
    Parkinsonism & related disorders, 2023, Volume: 110

    Topics: Benzimidazoles; Cognition Disorders; Cognitive Dysfunction; Humans; Neuropsychological Tests; Parkin

2023

Other Studies

3 other studies available for candesartan and Parkinson Disease

ArticleYear
Angiotensin type 1 receptor blockage reduces l-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of vascular endothelial growth factor and interleukin-1β.
    Experimental neurology, 2014, Volume: 261

    Topics: Adrenergic Agents; Angiotensin II Type 1 Receptor Blockers; Animals; Antiparkinson Agents; Benzimida

2014
Estrogen and angiotensin interaction in the substantia nigra. Relevance to postmenopausal Parkinson's disease.
    Experimental neurology, 2010, Volume: 224, Issue:2

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cell Death; Dopamine; Estradiol; Estrog

2010
Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration.
    Neurobiology of aging, 2012, Volume: 33, Issue:1

    Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Co

2012