Page last updated: 2024-10-24

candesartan and Obesity

candesartan has been researched along with Obesity in 29 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"In patients with hypertension and obesity showing insulin resistance, treatment with telmisartan significantly improved the hyperinsulin response to glucose loading."9.15Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE). ( Matsuura, K; Mori, Y; Tanaka, T; Utsunomiya, K; Yokoyama, J, 2011)
"We compared the effects of telmisartan with those of candesartan, on insulin sensitivity, the serum levels of various adipocytokines and oxidative stress."9.14Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients. ( Awata, T; Ikebukuro, K; Inukai, K; Ito, D; Katayama, S; Kurihara, S; Ono, H; Sumita, T; Watanabe, M, 2010)
" The aim of this study was to investigate whether weight reduction after AT(1)-blockade is dependent on dose, blood pressure reduction and leptin signalling."7.77Weight loss and hypophagia after high-dose AT1-blockade is only observed after high dosing and depends on regular leptin signalling but not blood pressure. ( Jöhren, O; Markert, A; Müller-Fielitz, H; Pahlke, F; Raasch, W; Wittmershaus, C, 2011)
" While taking candesartan for hypertension, a 53-year-old woman with known ACE inhibitor intolerance developed angioedema."7.71Angioedema associated with candesartan. ( Lo, KS, 2002)
"Insulin sensitivity was expressed as insulin resistance index (IRI), calculated as the ratio of the area under the curve (AUC) for glucose to that for insulin."6.71Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study. ( Bombelli, M; Dell'Oro, R; Facchini, A; Grassi, G; Mancia, G; Scopelliti, F; Seravalle, G; Trevano, FQ, 2003)
"In candesartan-treated db/db mice (1 mg/kg per day, 4 weeks) increased plasma aldosterone, CYP11B2 expression, and aldosterone secretion were reduced."5.38Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction. ( Briones, AM; Burger, D; Burns, KD; Callera, GE; Corrêa, JW; Gagnon, AM; Gomez-Sanchez, CE; Gomez-Sanchez, EP; He, Y; Nguyen Dinh Cat, A; Ooi, TC; Ruzicka, M; Sorisky, A; Touyz, RM; Yogi, A, 2012)
"Obesity has been strongly associated with the development and aggravation of hypertension and chronic kidney disease."5.36Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats. ( Chang, YS; Chung, HW; Chung, S; Kim, BS; Kim, GH; Kim, HW; Lee, JH; Lim, JH; Park, CW; Shin, SJ; Youn, DY, 2010)
"Candesartan treatment may suppress all-cause death and reduce the incidence of new-onset diabetes in patients with obesity."5.36Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial. ( Fujimoto, A; Hirata, M; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Ueshima, K; Yasuno, S, 2010)
"Candesartan was orally administered to 12-week-old rats for 21 days, and age-matched rats without the agent were used as the respective controls."5.31Candesartan inhibits carotid intimal thickening and ameliorates insulin resistance in balloon-injured diabetic rats. ( Daimon, M; Hirata, A; Igarashi, M; Kato, T; Ohnuma, H; Tominaga, M; Tsuchiya, H; Yamaguchi, H, 2001)
"A combination of a calcium channel blocker and angiotensin receptor blocker (lacidipine 2 mg, 4 mg, and candesartan 4mg, 8mg, 16mg) was prescribed to 30 patients with essential hypertension of grades 1-3, 30 to 65 years old (mean age - 54."5.27Beneficial effects of combined therapy with lacidipine and candesartan in obese hypertensive patients. ( Ashcheulova, T; Gerasimchuk, N; Honchar, O; Kovalyova, O, 2018)
"The present study by using the telemedicine system clearly demonstrated that telmisartan has a strong effect on reducing morning home BP, and a good effect on lipid metabolism in patients with metabolic syndrome."5.19Effectiveness of using long-acting angiotensin II type 1 receptor blocker in Japanese obese patients with metabolic syndrome on morning hypertension monitoring by using telemedicine system (FUJIYAMA study). ( Kinoshita, S; Nakamoto, H; Nishida, E; Ryuzaki, M; Sone, M, 2014)
"In patients with hypertension and obesity showing insulin resistance, treatment with telmisartan significantly improved the hyperinsulin response to glucose loading."5.15Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE). ( Matsuura, K; Mori, Y; Tanaka, T; Utsunomiya, K; Yokoyama, J, 2011)
"The reduction in proteinuria induced by lisinopril (11."5.14[The antiproteinuric effect of the blockage of the renin-angiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? ]. ( Gutiérrez Solís, E; Gutiérrez, E; Huerta, A; Morales, E; Praga, M; Segura, J, 2009)
"We compared the effects of telmisartan with those of candesartan, on insulin sensitivity, the serum levels of various adipocytokines and oxidative stress."5.14Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients. ( Awata, T; Ikebukuro, K; Inukai, K; Ito, D; Katayama, S; Kurihara, S; Ono, H; Sumita, T; Watanabe, M, 2010)
" CD-fed SHR were simultaneously treated with either telmisartan (TEL; 8 mg/kg(body weight)· d) or candesartan (CAND; 10 mg/kg(body weight)· d) for 3 months because TEL, but not CAND, has been demonstrated to be a strong activator of PPARγ."3.78Improved insulin sensitivity after long-term treatment with AT1 blockers is not associated with PPARγ target gene regulation. ( Heidbreder, M; Jöhren, O; Landolt, J; Müller-Fielitz, H; Raasch, W; Vogt, FM; Werth, S, 2012)
" The aim of this study was to investigate whether weight reduction after AT(1)-blockade is dependent on dose, blood pressure reduction and leptin signalling."3.77Weight loss and hypophagia after high-dose AT1-blockade is only observed after high dosing and depends on regular leptin signalling but not blood pressure. ( Jöhren, O; Markert, A; Müller-Fielitz, H; Pahlke, F; Raasch, W; Wittmershaus, C, 2011)
" While taking candesartan for hypertension, a 53-year-old woman with known ACE inhibitor intolerance developed angioedema."3.71Angioedema associated with candesartan. ( Lo, KS, 2002)
"Insulin sensitivity was expressed as insulin resistance index (IRI), calculated as the ratio of the area under the curve (AUC) for glucose to that for insulin."2.71Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study. ( Bombelli, M; Dell'Oro, R; Facchini, A; Grassi, G; Mancia, G; Scopelliti, F; Seravalle, G; Trevano, FQ, 2003)
"Treatment with amlodipine, candesartan, or indapamide did not significantly affect plasma visfatin levels."1.43Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations. ( Piecha, G; Skoczylas, A; Więcek, A, 2016)
"In candesartan-treated db/db mice (1 mg/kg per day, 4 weeks) increased plasma aldosterone, CYP11B2 expression, and aldosterone secretion were reduced."1.38Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction. ( Briones, AM; Burger, D; Burns, KD; Callera, GE; Corrêa, JW; Gagnon, AM; Gomez-Sanchez, CE; Gomez-Sanchez, EP; He, Y; Nguyen Dinh Cat, A; Ooi, TC; Ruzicka, M; Sorisky, A; Touyz, RM; Yogi, A, 2012)
"Obesity has been strongly associated with the development and aggravation of hypertension and chronic kidney disease."1.36Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats. ( Chang, YS; Chung, HW; Chung, S; Kim, BS; Kim, GH; Kim, HW; Lee, JH; Lim, JH; Park, CW; Shin, SJ; Youn, DY, 2010)
"Candesartan treatment may suppress all-cause death and reduce the incidence of new-onset diabetes in patients with obesity."1.36Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial. ( Fujimoto, A; Hirata, M; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Ueshima, K; Yasuno, S, 2010)
"The metabolic syndrome is a risk factor for the development of chronic kidney disease."1.35Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet. ( Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N, 2008)
"Candesartan was orally administered to 12-week-old rats for 21 days, and age-matched rats without the agent were used as the respective controls."1.31Candesartan inhibits carotid intimal thickening and ameliorates insulin resistance in balloon-injured diabetic rats. ( Daimon, M; Hirata, A; Igarashi, M; Kato, T; Ohnuma, H; Tominaga, M; Tsuchiya, H; Yamaguchi, H, 2001)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (37.93)29.6817
2010's18 (62.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashcheulova, T1
Gerasimchuk, N1
Kovalyova, O1
Honchar, O1
Kinoshita, S1
Ryuzaki, M1
Sone, M1
Nishida, E1
Nakamoto, H1
Luo, H1
Wang, X3
Chen, C1
Wang, J1
Zou, X1
Li, C1
Xu, Z1
Yang, X1
Shi, W1
Zeng, C1
Takahashi, F1
Goto, M1
Wada, Y1
Hasebe, N1
Skoczylas, A1
Piecha, G1
Więcek, A1
Namikoshi, T1
Tomita, N1
Satoh, M1
Haruna, Y1
Kobayashi, S1
Komai, N1
Sasaki, T1
Kashihara, N1
Clodi, M1
Resl, M1
Stelzeneder, D1
Pacini, G1
Tura, A1
Mörtl, D1
Struck, J1
Morgenthaler, NG1
Bergmann, A1
Riedl, M1
Anderwald-Stadler, M1
Luger, A1
Pacher, R1
Hülsmann, M1
Hu, J1
Tiwari, S3
Riazi, S2
Hu, X2
Ecelbarger, CM4
Yamauchi, T1
Kadowaki, T1
Chung, S1
Park, CW1
Shin, SJ1
Lim, JH1
Chung, HW1
Youn, DY1
Kim, HW1
Kim, BS1
Lee, JH1
Kim, GH1
Chang, YS1
Morales, E1
Huerta, A1
Gutiérrez, E1
Gutiérrez Solís, E1
Segura, J1
Praga, M1
Fukuda, M1
Nakamura, T1
Kataoka, K1
Nako, H1
Tokutomi, Y1
Dong, YF1
Ogawa, H1
Kim-Mitsuyama, S1
Nakao, K1
Hirata, M1
Oba, K1
Yasuno, S1
Ueshima, K1
Fujimoto, A1
Ogihara, T1
Saruta, T1
Rash, A1
Sinha, RK1
Barrios, V1
Escobar, C1
Calderon, A1
Li, F1
Jose, PA1
Watanabe, M1
Inukai, K1
Sumita, T1
Ikebukuro, K1
Ito, D1
Kurihara, S1
Ono, H1
Awata, T1
Katayama, S1
Yan, WH1
Pan, CY1
Dou, JT1
Ma, FL1
Wang, XM1
Yang, GQ1
Wang, XL1
Mu, YM1
Lu, JM1
Müller-Fielitz, H2
Markert, A1
Wittmershaus, C1
Pahlke, F1
Jöhren, O2
Raasch, W2
Mori, Y1
Tanaka, T1
Matsuura, K1
Yokoyama, J1
Utsunomiya, K1
Landolt, J1
Heidbreder, M1
Werth, S1
Vogt, FM1
Eppel, GA1
Head, GA1
Denton, KM1
Evans, RG1
Briones, AM1
Nguyen Dinh Cat, A1
Callera, GE1
Yogi, A1
Burger, D1
He, Y1
Corrêa, JW1
Gagnon, AM1
Gomez-Sanchez, CE1
Gomez-Sanchez, EP1
Sorisky, A1
Ooi, TC1
Ruzicka, M1
Burns, KD1
Touyz, RM1
Lo, KS1
Grassi, G1
Seravalle, G1
Dell'Oro, R1
Trevano, FQ1
Bombelli, M1
Scopelliti, F1
Facchini, A1
Mancia, G1
Hakam, AC1
Hussain, T1
Kotovskaia, IuV1
Kobalava, ZhD1
Madala Halagappa, VK1
Igarashi, M1
Hirata, A1
Yamaguchi, H1
Tsuchiya, H1
Ohnuma, H1
Tominaga, M1
Daimon, M1
Kato, T1

Reviews

1 review available for candesartan and Obesity

ArticleYear
[Anti-metabolic syndrome effects of candesartan].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:2

    Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; D

2009

Trials

8 trials available for candesartan and Obesity

ArticleYear
Beneficial effects of combined therapy with lacidipine and candesartan in obese hypertensive patients.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2018, Dec-01, Volume: 56, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Case-Control Studies; Dihy

2018
Effectiveness of using long-acting angiotensin II type 1 receptor blocker in Japanese obese patients with metabolic syndrome on morning hypertension monitoring by using telemedicine system (FUJIYAMA study).
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:7

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles

2014
Interactions of glucose metabolism and chronic heart failure.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2009, Volume: 117, Issue:3

    Topics: Benzimidazoles; Benzoates; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Chronic Di

2009
[The antiproteinuric effect of the blockage of the renin-angiotensin-aldosterone system (RAAS) in obese patients. Which treatment option is the most effective? ].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009, Volume: 29, Issue:5

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benz

2009
Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:17

    Topics: Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles;

2010
Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE).
    Advances in therapy, 2011, Volume: 28, Issue:8

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; B

2011
Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study.
    Journal of hypertension, 2003, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose;

2003
[Is primary prevention of arterial hypertension with drugs possible? Results of the TROPHY Study].
    Kardiologiia, 2006, Volume: 46, Issue:10

    Topics: Benzimidazoles; Biphenyl Compounds; Cholesterol, LDL; Female; Humans; Hypertension; Male; Middle Age

2006

Other Studies

20 other studies available for candesartan and Obesity

ArticleYear
Oxidative stress causes imbalance of renal renin angiotensin system (RAS) components and hypertension in obese Zucker rats.
    Journal of the American Heart Association, 2015, Feb-16, Volume: 4, Issue:2

    Topics: Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Disease

2015
Successful Treatment with an Antihypertensive Drug Regimen Including Eplerenone in a Patient with Malignant Phase Hypertension with Renal Failure.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:19

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cal

2015
Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations.
    Polskie Archiwum Medycyny Wewnetrznej, 2016, Apr-29, Volume: 126, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers;

2016
Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dietary Protei

2008
Regulation of angiotensin II type I receptor (AT1R) protein levels in the obese Zucker rat kidney and urine.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biomarker

2009
Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:2

    Topics: Animals; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cyclic N-Oxides;

2010
Potentiation by candesartan of protective effects of pioglitazone against type 2 diabetic cardiovascular and renal complications in obese mice.
    Journal of hypertension, 2010, Volume: 28, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds;

2010
Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:6

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles;

2010
The effect of chronic candesartan therapy on the metabolic profile and renal tissue cytokine levels in the obese Zucker rat.
    Mediators of inflammation, 2010, Volume: 2010

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cytokines; Die

2010
Cardiovascular protection with candesartan in patients with metabolic disorders.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases

2010
Reduction of renal dopamine receptor expression in obese Zucker rats: role of sex and angiotensin II.
    American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds

2010
[Effects of candesartan on expressions of JAK2 and PTP-1B in adipose tissue of high-fat diet-fed rats].
    Zhonghua yi xue za zhi, 2010, Jul-13, Volume: 90, Issue:26

    Topics: Adipose Tissue; Animals; Benzimidazoles; Biphenyl Compounds; Insulin Resistance; Janus Kinase 2; Mal

2010
Weight loss and hypophagia after high-dose AT1-blockade is only observed after high dosing and depends on regular leptin signalling but not blood pressure.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure

2011
Improved insulin sensitivity after long-term treatment with AT1 blockers is not associated with PPARγ target gene regulation.
    Endocrinology, 2012, Volume: 153, Issue:3

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Co

2012
Effects of tempol and candesartan on neural control of the kidney.
    Autonomic neuroscience : basic & clinical, 2012, May-21, Volume: 168, Issue:1-2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biph

2012
Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Adipocytes; Aldosterone; Animals; Benzimidazoles; Biphenyl Compounds; Calcineurin; Cells, Cultured;

2012
Angioedema associated with candesartan.
    Pharmacotherapy, 2002, Volume: 22, Issue:9

    Topics: Angioedema; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Hypersensitivity; Fema

2002
Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds

2005
Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:5

    Topics: Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Bipheny

2008
Candesartan inhibits carotid intimal thickening and ameliorates insulin resistance in balloon-injured diabetic rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Carotid Artery, Commo

2001