candesartan has been researched along with Muscle Contraction in 11 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The angiotensin II type 1 (AT1) receptor has a crucial role in load-induced cardiac hypertrophy." | 3.72 | Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. ( Akazawa, H; Fujita, T; Fukamizu, A; Iiri, T; Iwanaga, K; Kihara, M; Komuro, I; Kudoh, S; Makita, N; Minamino, T; Nagai, T; Qin, Y; Sano, M; Takano, H; Tamura, K; Toko, H; Umemura, S; Zhu, W; Zou, Y, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wagenaar, LJ | 1 |
| Voors, AA | 1 |
| Buikema, H | 2 |
| van Buiten, A | 1 |
| Lübeck, RH | 1 |
| Boonstra, PW | 1 |
| van Veldhuisen, DJ | 1 |
| van Gilst, WH | 1 |
| Tiefenbacher, CP | 1 |
| Friedrich, S | 1 |
| Bleeke, T | 1 |
| Vahl, C | 1 |
| Chen, X | 1 |
| Niroomand, F | 1 |
| Zou, Y | 1 |
| Akazawa, H | 1 |
| Qin, Y | 1 |
| Sano, M | 1 |
| Takano, H | 1 |
| Minamino, T | 1 |
| Makita, N | 1 |
| Iwanaga, K | 1 |
| Zhu, W | 1 |
| Kudoh, S | 1 |
| Toko, H | 1 |
| Tamura, K | 1 |
| Kihara, M | 1 |
| Nagai, T | 1 |
| Fukamizu, A | 1 |
| Umemura, S | 1 |
| Iiri, T | 1 |
| Fujita, T | 1 |
| Komuro, I | 1 |
| Casselbrant, A | 1 |
| Edebo, A | 1 |
| Wennerblom, J | 1 |
| Lönroth, H | 1 |
| Helander, HF | 1 |
| Vieth, M | 1 |
| Lundell, L | 1 |
| Fändriks, L | 1 |
| Hara, M | 1 |
| Kiyama, R | 1 |
| Nakajima, S | 1 |
| Kawabata, T | 1 |
| Kawakami, M | 1 |
| Ohtani, K | 1 |
| Itazaki, K | 1 |
| Fujishita, T | 1 |
| Fujimoto, M | 1 |
| Nishikawa, K | 2 |
| Inada, Y | 2 |
| Shibouta, Y | 2 |
| Wada, T | 2 |
| Ojima, M | 2 |
| Kubo, K | 2 |
| Naka, T | 2 |
| Noda, M | 1 |
| Sanada, T | 1 |
| Kohara, Y | 1 |
| Onaka, U | 1 |
| Fujii, K | 1 |
| Abe, I | 1 |
| Fujishima, M | 1 |
| Nishimura, H | 1 |
| Baltatu, O | 1 |
| Ganten, D | 1 |
| Urata, H | 1 |
| Zhou, MS | 1 |
| Nishida, Y | 1 |
| Chen, QH | 1 |
| Murakami, H | 1 |
| Hosomi, H | 1 |
| Kosaka, H | 1 |
| Morsing, P | 1 |
| Adler, G | 1 |
| Brandt-Eliasson, U | 1 |
| Karp, L | 1 |
| Ohlson, K | 1 |
| Renberg, L | 1 |
| Sjöquist, PO | 1 |
| Abrahamsson, T | 1 |
1 trial available for candesartan and Muscle Contraction
| Article | Year |
|---|---|
Actions by angiotensin II on esophageal contractility in humans.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; B | 2007 |
10 other studies available for candesartan and Muscle Contraction
| Article | Year |
|---|---|
Functional antagonism of different angiotensin II type I receptor blockers in human arteries.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Dose-Response | 2002 |
ACE inhibitors and statins acutely improve endothelial dysfunction of human coronary arterioles.
Topics: Acetylcholine; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibito | 2004 |
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds | 2004 |
Kinetic studies on the interaction of nonlabeled antagonists with the angiotensin II receptor.
Topics: Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Binding, Competitive; Biphenyl Com | 1995 |
Pharmacological profile of a novel nonpeptide angiotensin II subtype 1 receptor antagonist, TCV-116.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compoun | 1994 |
Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethy
Topics: Adrenal Cortex; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihype | 1993 |
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Ani | 1997 |
Functional evidence for alternative ANG II-forming pathways in hamster cardiovascular system.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Aprotinin | 1998 |
Is a hypertensinogenic factor present in the kidney of hypertensive dahl rats?
Topics: Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aorta; Benzimidazoles; Biphenyl Compound | 1998 |
Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimida | 1999 |