Page last updated: 2024-10-24

candesartan and Migraine Disorders

candesartan has been researched along with Migraine Disorders in 17 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"We describe the use of the antihypertensive, candesartan, with hydrochlorothiazide (ECARD Combination Tablets LD) as a preventive therapy that decreased the frequency of migraine accompanied by premonitory leg edema."3.79Migraine treated using a prophylactic combination of candesartan and hydrochlorothiazide (ECARD Combination Tablets LD). ( Akiyama, H; Hasegawa, Y, 2013)
" Rates of adverse events were similar for patients using and not using preventive medications."2.90Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials. ( Ailani, J; Baygani, S; Hundemer, HP; Krege, JH; Loo, LS; Port, M; Schim, J, 2019)
"Candesartan was non-inferior to propranolol (and vice versa)."2.79A comparative study of candesartan versus propranolol for migraine prophylaxis: A randomised, triple-blind, placebo-controlled, double cross-over study. ( Aamodt, AH; Gravdahl, GB; Hagen, K; Linde, M; Sand, T; Stovner, LJ; Tronvik, E, 2014)
"The treatment of migraine depends on the frequency, severity and concomitant diseases."2.52[Role of antihypertensive drugs in the treatment of migraine]. ( Fehér, G; Pusch, G, 2015)
"Mild migraine attack can be treated with acetaminophen or NSAIDs either alone or combined with metoclopramide."2.52[Update on Current Care Guideline: Migraine]. ( , 2015)
"Lamotrigine is ineffective for migraine prevention (Level A)."2.48Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. ( Argoff, C; Ashman, E; Dodick, DW; Freitag, F; Holland, S; Silberstein, SD, 2012)
"ACE inhibitors and ARBs have migraine prophylaxis activity similar to that of some currently utilized agents."2.46Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for the prevention of migraines. ( Bailey, EK; Gales, BJ; Gales, MA; Reed, AN, 2010)
"Eighty-four patients (70%) had chronic migraine and 53 (42."1.62Real world effectiveness and tolerability of candesartan in the treatment of migraine: a retrospective cohort study. ( García-Azorín, D; Guerrero, ÁL; Martínez-Pías, E; Planchuelo-Gómez, Á; Sánchez-Rodríguez, C; Sierra, Á, 2021)
"Eighty-one patients (chronic migraine, n = 68) were included in the final analysis."1.56Candesartan in migraine prevention: results from a retrospective real-world study. ( Filippi, M; Goadsby, PJ; Lastarria Perez, CP; Messina, R, 2020)
"A pregnant young woman with a severe migraine is prescribed candesartan, an angiotensin II type 1 receptor antagonist (AT II antagonists)."1.36Angiotensin II receptor antagonists against migraine in pregnancy: fatal outcome. ( Haaland, K, 2010)
"347 migraine patients aged 18-68 (155 migraine without aura (MoA), 187 migraine with aura (MwA) and 5 missing aura subgroup data) and 403 healthy non-migrainous controls > 40 years of age were included in the study."1.35Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients. ( Bovim, G; Gladwin, AJ; Owen, K; Schrader, H; Stovner, LJ; Tronvik, E; White, LR, 2008)
"Thus candesartan is considered to be a unique, attractive choice of prophylactic agent for migraine complicated by hypertension."1.32Efficacy of candesartan in the treatment of migraine in hypertensive patients. ( Owada, K, 2004)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (35.29)29.6817
2010's9 (52.94)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Messina, R1
Lastarria Perez, CP1
Filippi, M1
Goadsby, PJ1
Sánchez-Rodríguez, C1
Sierra, Á1
Planchuelo-Gómez, Á1
Martínez-Pías, E1
Guerrero, ÁL1
García-Azorín, D1
Morris, B1
Neher, J1
Safranek, S1
Loo, LS1
Ailani, J1
Schim, J1
Baygani, S1
Hundemer, HP1
Port, M1
Krege, JH1
Stovner, LJ4
Linde, M1
Gravdahl, GB1
Tronvik, E3
Aamodt, AH1
Sand, T2
Hagen, K1
Fehér, G1
Pusch, G1
Haaland, K1
Gales, BJ1
Bailey, EK1
Reed, AN1
Gales, MA1
Silberstein, SD1
Holland, S1
Freitag, F1
Dodick, DW1
Argoff, C1
Ashman, E1
Akiyama, H1
Hasegawa, Y1
Helde, G1
Bovim, G2
Owada, K1
Rapoport, AM1
Bigal, ME1
White, LR1
Gladwin, AJ1
Owen, K1
Schrader, H1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Study of Two Doses of LAsMiditan (100 mg and 200 mg) Compared to Placebo in the AcUte Treatment of MigRAIne: A Randomized, Double-blind, Placebo-controlled Parallel Group Study[NCT02439320]Phase 32,231 participants (Actual)Interventional2015-04-30Completed
A Study of Three Doses of Lasmiditan (50 mg, 100 mg and 200 mg) Compared to Placebo in the Acute TReaTment of MigrAiNe: A Randomized, Double-blind, Placebo-controlled Parallel Group Study (SPARTAN)[NCT02605174]Phase 33,005 participants (Actual)Interventional2016-05-31Completed
CandeSpartan Study Candesartan Spanish Response-prediction and Tolerability Study Observational Study on Response Predictors and Tolerability of Candesartan in Usual Clinical Practice[NCT04138316]85 participants (Actual)Observational [Patient Registry]2020-01-02Completed
Candesartan vs Propranolol for Migraine Prevention: A Double Blind, Placebo Controlled, Double Dummy, Triple Cross-over Study[NCT00884663]Phase 2/Phase 372 participants (Actual)Interventional2009-04-30Completed
Prophylactic Treatment of Episodic Cluster Headache With an Angiotensin II Receptor Blocker (Candesartan Cilexetil); a Randomized, Placebo Controlled Parallel Study[NCT00184587]Phase 240 participants (Actual)Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Participants With Serious Adverse Events (SAE)

Safety and Tolerability was assessed by the number of participants with at least 1 treatment emergent event (TEAE). A summary of other non-serious adverse events and all serious adverse events, regardless of causality, is located in the Reported Adverse Events Section (NCT02439320)
Timeframe: Baseline up to 11 weeks

InterventionParticipants (Count of Participants)
100 mg Lasmiditan0
200 mg Lasmiditan2
Placebo1

Percentage of Participants Nausea Free

The percentage of participants without nausea. (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan64.6
200 mg Lasmiditan64.1
Placebo62.1

Percentage of Participants Phonophobia Free

The percentage of participants without phonophobia. (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan60.7
200 mg Lasmiditan58.7
Placebo52.5

Percentage of Participants Photophobia Free

The percentage of participants without photophobia. (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan53.9
200 mg Lasmiditan51.5
Placebo38.1

Percentage of Participants Who Are Headache Pain Free

The percentage of participants defined as mild, moderate, or severe headache pain becoming none. (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan28.2
200 mg Lasmiditan32.2
Placebo15.3

Percentage of Participants Who Are Most Bothersome Symptom (MBS) Free

The percentage of participants defined as the associated symptom present and identified as MBS (nausea, photophobia, or phonophobia) prior to dosing being absent. (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan40.9
200 mg Lasmiditan40.7
Placebo29.5

Percentage of Participants Who Have Headache Relief After First Dose

The percentage of participants with headache pain moderate or severe which became mild or none or with headache pain mild which became none. (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan59.4
200 mg Lasmiditan59.5
Placebo42.2

Percentage of Participants Who Used Rescue Medication

Rescue medication was permitted after completion of the 2 hour assessment if the migraine did not respond (participant was not pain free). (NCT02439320)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan26.2
200 mg Lasmiditan20.7
Placebo46.0

Percentage of Participants Who Used Rescue Medication

Rescue medication was permitted after completion of the 2 hour assessment if the migraine did not respond (participant was not pain free). (NCT02439320)
Timeframe: Anytime 24-48 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan0
200 mg Lasmiditan0
Placebo0

Percentage of Participants Who Used Rescue Medication

Rescue medication was permitted after completion of the 2 hour assessment if the migraine did not respond (participant was not pain free). (NCT02439320)
Timeframe: Anytime between 2-24 hours post dose

Interventionpercentage of participants (Number)
100 mg Lasmiditan8.9
200 mg Lasmiditan7.9
Placebo11.7

Percentage of Participants With Headache Recurrence

Participants who received study drug and which became pain free at 2 hours post-dose and worsened again up to 48 hours post-dose. (NCT02439320)
Timeframe: From 2 hours post dose up to 48 hours

Interventionpercentage of participants (Number)
100 mg Lasmiditan8.4
200 mg Lasmiditan10.1
Placebo5.1

Percentage of Participants With Resource Utilization

Use of health care for treatment 6 months prior to enrolling in the study and information reported during time on study (NCT02439320)
Timeframe: 6 months prior to enrolling in study to end of study (Up to 11 Weeks) within 7 days of treating a single migraine attack

,,,,
Interventionpercentage of participants (Number)
6 Months prior to enrollingDuring time of study
100 mg Lasmiditan/100 mg Lasmiditan4.40.9
100 mg Lasmiditan/Placebo4.60.5
200 mg Lasmiditan/200 mg Lasmiditan3.00.2
200 mg Lasmiditan/Placebo2.50.5
Placebo/Placebo2.80.6

Number of Participants With Headache Recurrence

The number of participants with headache recurrence (moderate or severe at baseline which became pain-free at 2 hours post dose and worsened again up to 48 hours post dose) (NCT02605174)
Timeframe: From 2 Hours Post Dose Up to 48 Hours

InterventionParticipants (Count of Participants)
Lasmiditan 50 mg38
Lasmiditan 100 mg44
Lasmiditan 200 mg52
Placebo26

Number of Participants With Treatment Emergent Events

Safety and Tolerability was assessed by the number of participants with at least 1 treatment emergent event (TEAE). A summary of other non-serious adverse events and all serious adverse events, regardless of causality, is located in the Reported Adverse Events Section (NCT02605174)
Timeframe: From Baseline Up to End of Study (Up to 11 Weeks)

Interventionparticipants (Number)
Lasmiditan 50 mg167
Lasmiditan 100 mg230
Lasmiditan 200 mg253
Placebo75

Percentage of Participants Headache Pain Free at 2 Hours Post Dose

The percentage of participants defined as mild, moderate, or severe headache pain becoming none. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg28.6
Lasmiditan 100 mg31.4
Lasmiditan 200 mg38.8
Placebo21.3

Percentage of Participants Nausea Free

The percentage of participant without nausea. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg68.7
Lasmiditan 100 mg71.8
Lasmiditan 200 mg70.4
Placebo70.3

Percentage of Participants Use of Rescue Medication

The percentage of participants who used rescue medication. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg31.9
Lasmiditan 100 mg26.4
Lasmiditan 200 mg18.9
Placebo40.8

Percentage of Participants Use of Rescue Medication

The percentage of participants who used rescue medication. (NCT02605174)
Timeframe: From 2 Hours Post Dose Up to 24 Hours

Interventionpercentage of participants (Number)
Lasmiditan 50 mg8.9
Lasmiditan 100 mg6.3
Lasmiditan 200 mg7.4
Placebo8.7

Percentage of Participants Use of Rescue Medication

The percentage of participants who used rescue medication. (NCT02605174)
Timeframe: From 24 Post Dose Up to 48 Hours

Interventionpercentage of participants (Number)
Lasmiditan 50 mg0.0
Lasmiditan 100 mg0.0
Lasmiditan 200 mg0.0
Placebo0.0

Percentage of Participants Who Are Most Bothersome Symptom (MBS) Free

The percentage of participants defined as the associated symptom present and identified as MBS (nausea, photophobia, or phonophobia) prior to dosing being absent. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg40.8
Lasmiditan 100 mg44.2
Lasmiditan 200 mg48.7
Placebo33.5

Percentage of Participants With Headache Relief

The percentage of participants with headache pain moderate or severe which became mild or none or with headache pain mild which became none. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg59.0
Lasmiditan 100 mg64.8
Lasmiditan 200 mg65.0
Placebo47.7

Percentage of Participants With Phonophobia Free

The percentage of participants without phonophobia. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg61.2
Lasmiditan 100 mg64.8
Lasmiditan 200 mg65.3
Placebo53.5

Percentage of Participants With Photophobia Free

The percentage of participants without photophobia. (NCT02605174)
Timeframe: 2 hours post dose

Interventionpercentage of participants (Number)
Lasmiditan 50 mg51.2
Lasmiditan 100 mg56.4
Lasmiditan 200 mg58.2
Placebo43.2

Percentage of Participants With Resource Utilization

Use of health care for treatment 6 months prior to enrolling in the study and information reported during time on study (NCT02605174)
Timeframe: 6 Months Prior to Enrolling in Study to End of Study (Up to 11 Weeks) Within 7 Days of Treating a Single Migraine Attack

,,,,,,
Interventionpercentage of participants (Number)
6 months prior to enrollingDuring time of study
Lasmiditan 100 mg/Lasmiditan 100 mg2.80.5
Lasmiditan 100 mg/Placebo2.40
Lasmiditan 200 mg/Lasmiditan 200 mg3.20.9
Lasmiditan 200 mg/Placebo3.30.5
Lasmiditan 50 mg/Lasmiditan 50 mg4.70.5
Lasmiditan 50 mg/Placebo2.20
Placebo/Placebo2.90.6

Reviews

6 reviews available for candesartan and Migraine Disorders

ArticleYear
Clinical Inquiries. How effectively do ACE inhibitors and ARBs prevent migraines?
    The Journal of family practice, 2018, Volume: 67, Issue:10

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl

2018
[Role of antihypertensive drugs in the treatment of migraine].
    Orvosi hetilap, 2015, Feb-01, Volume: 156, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2015
[Update on Current Care Guideline: Migraine].
    Duodecim; laaketieteellinen aikakauskirja, 2015, Volume: 131, Issue:19

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opi

2015
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for the prevention of migraines.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2010
Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society.
    Neurology, 2012, Apr-24, Volume: 78, Issue:17

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2012
Preventive migraine therapy: what is new.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3

    Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Second-Generation; Anti

2004

Trials

3 trials available for candesartan and Migraine Disorders

ArticleYear
Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials.
    The journal of headache and pain, 2019, Jul-24, Volume: 20, Issue:1

    Topics: Adult; Benzamides; Benzimidazoles; Biphenyl Compounds; Botulinum Toxins, Type A; Double-Blind Method

2019
Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials.
    The journal of headache and pain, 2019, Jul-24, Volume: 20, Issue:1

    Topics: Adult; Benzamides; Benzimidazoles; Biphenyl Compounds; Botulinum Toxins, Type A; Double-Blind Method

2019
Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials.
    The journal of headache and pain, 2019, Jul-24, Volume: 20, Issue:1

    Topics: Adult; Benzamides; Benzimidazoles; Biphenyl Compounds; Botulinum Toxins, Type A; Double-Blind Method

2019
Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials.
    The journal of headache and pain, 2019, Jul-24, Volume: 20, Issue:1

    Topics: Adult; Benzamides; Benzimidazoles; Biphenyl Compounds; Botulinum Toxins, Type A; Double-Blind Method

2019
A comparative study of candesartan versus propranolol for migraine prophylaxis: A randomised, triple-blind, placebo-controlled, double cross-over study.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:7

    Topics: Adult; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Humans;

2014
A comparative study of candesartan versus propranolol for migraine prophylaxis: A randomised, triple-blind, placebo-controlled, double cross-over study.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:7

    Topics: Adult; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Humans;

2014
A comparative study of candesartan versus propranolol for migraine prophylaxis: A randomised, triple-blind, placebo-controlled, double cross-over study.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:7

    Topics: Adult; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Humans;

2014
A comparative study of candesartan versus propranolol for migraine prophylaxis: A randomised, triple-blind, placebo-controlled, double cross-over study.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:7

    Topics: Adult; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Humans;

2014
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003
Prophylactic treatment of migraine with an angiotensin II receptor blocker: a randomized controlled trial.
    JAMA, 2003, Jan-01, Volume: 289, Issue:1

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cross-O

2003

Other Studies

8 other studies available for candesartan and Migraine Disorders

ArticleYear
Candesartan in migraine prevention: results from a retrospective real-world study.
    Journal of neurology, 2020, Volume: 267, Issue:11

    Topics: Benzimidazoles; Biphenyl Compounds; Humans; London; Migraine Disorders; Retrospective Studies; Tetra

2020
Real world effectiveness and tolerability of candesartan in the treatment of migraine: a retrospective cohort study.
    Scientific reports, 2021, 02-15, Volume: 11, Issue:1

    Topics: Benzimidazoles; Biphenyl Compounds; Disease Management; Duration of Therapy; Female; Headache; Human

2021
Angiotensin II receptor antagonists against migraine in pregnancy: fatal outcome.
    The journal of headache and pain, 2010, Volume: 11, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting

2010
Migraine treated using a prophylactic combination of candesartan and hydrochlorothiazide (ECARD Combination Tablets LD).
    Pain practice : the official journal of World Institute of Pain, 2013, Volume: 13, Issue:7

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Combinations; Edema; Female

2013
BP drug for migraine prevention.
    Health news (Waltham, Mass.), 2003, Volume: 9, Issue:3

    Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Human

2003
Efficacy of candesartan in the treatment of migraine in hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:6

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans;

2004
Migraine prophylaxis with drugs influencing the renin-angiotensin system.
    European journal of neurology, 2007, Volume: 14, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; B

2007
Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients.
    BMC neurology, 2008, Mar-26, Volume: 8

    Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhi

2008