candesartan has been researched along with Injury, Myocardial Reperfusion in 17 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The calcium antagonist felodipine, the lipid-peroxidation inhibitor H290/51, and the angiotensin II type 1 (AT1)-receptor antagonist candesartan all exert beneficial effects on myocardial ischemia/reperfusion injury." | 3.70 | Combination of a calcium antagonist, a lipid-peroxidation inhibitor, and an angiotensin AT1-receptor antagonist provides additive myocardial infarct size-limiting effect in pigs. ( Rydén, L; Shimizu, M; Sjöquist, PO; Wang, QD, 1999) |
| " The authors established with an initial dose-response curve using escalating concentrations of CN that 10 nmol/L abrogated vasoconstriction induced by angiotensin II (0." | 1.31 | Increased AT(2)R protein expression but not increased apoptosis during cardioprotection induced by AT(1)R blockade. ( Jugdutt, BI; Kumar, D; Moudgil, R; Musat-Marcu, S; Xu, Y, 2002) |
| "Candesartan was intravenously administered 30 min before ischemia." | 1.31 | An angiotensin II type 1 receptor blocker, candesartan, increases myocardial apoptosis in rats with acute ischemia-reperfusion. ( Chen, M; Hamada, M; Hiasa, G; Hiwada, K; Ikeda, S; Suzuki, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Songur, CM | 1 |
| Songur, MO | 1 |
| Kocabeyoglu, SS | 1 |
| Basgut, B | 1 |
| Taniguchi, Y | 1 |
| Takahashi, N | 1 |
| Fukui, A | 1 |
| Nagano-Torigoe, Y | 1 |
| Thuc, LC | 1 |
| Teshima, Y | 1 |
| Shinohara, T | 1 |
| Wakisaka, O | 1 |
| Ooie, T | 1 |
| Murozono, Y | 1 |
| Yufu, K | 1 |
| Nakagawa, M | 2 |
| Hara, M | 1 |
| Yoshimatsu, H | 1 |
| Saikawa, T | 1 |
| Jehle, AB | 1 |
| Xu, Y | 3 |
| Dimaria, JM | 1 |
| French, BA | 1 |
| Epstein, FH | 1 |
| Berr, SS | 1 |
| Roy, RJ | 1 |
| Kemp, BA | 1 |
| Carey, RM | 1 |
| Kramer, CM | 1 |
| Fukumoto, T | 1 |
| Tawa, M | 1 |
| Kitada, K | 1 |
| Yamashita, N | 1 |
| Ohkita, M | 1 |
| Okamura, T | 1 |
| Matsumura, Y | 1 |
| Moudgil, R | 2 |
| Musat-Marcu, S | 1 |
| Kumar, D | 1 |
| Jugdutt, BI | 2 |
| Harada, K | 1 |
| Komuro, I | 1 |
| Hayashi, D | 1 |
| Sugaya, T | 1 |
| Murakami, K | 1 |
| Yazaki, Y | 1 |
| Shimizu, M | 3 |
| Wang, QD | 4 |
| Sjöquist, PO | 4 |
| Rydén, L | 3 |
| Matoba, S | 1 |
| Tatsumi, T | 1 |
| Keira, N | 1 |
| Kawahara, A | 1 |
| Akashi, K | 1 |
| Kobara, M | 1 |
| Asayama, J | 1 |
| Sharma, A | 1 |
| Singh, M | 1 |
| Kawabata, H | 3 |
| Ryomoto, T | 3 |
| Ishikawa, K | 3 |
| Balghith, M | 1 |
| Menon, V | 1 |
| Chen, M | 1 |
| Hamada, M | 1 |
| Hiasa, G | 1 |
| Suzuki, M | 1 |
| Ikeda, S | 1 |
| Hiwada, K | 1 |
17 other studies available for candesartan and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Effects of the AT1 receptor blocker candesartan on myocardial ischemia/reperfusion in isolated rat hearts.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; In Vitro Techn | 2014 |
Candesartan restored cardiac Hsp72 expression and tolerance against reperfusion injury in hereditary insulin-resistant rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; | 2011 |
A nonpeptide angiotensin II type 2 receptor agonist does not attenuate postmyocardial infarction left ventricular remodeling in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Occlu | 2012 |
Different effects of AT1 receptor antagonist and ET(A) receptor antagonist on ischemia-induced norepinephrine release in rat hearts.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Di | 2012 |
Increased AT(2)R protein expression but not increased apoptosis during cardioprotection induced by AT(1)R blockade.
Topics: Analysis of Variance; Animals; Apoptosis; Benzimidazoles; Biphenyl Compounds; Culture Techniques; Di | 2002 |
Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias.
Topics: Angiotensin Receptor Antagonists; Animals; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; | 1998 |
Angiotensin II type 1 receptor blockade with candesartan protects the porcine myocardium from reperfusion-induced injury.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; | 1998 |
Effects of the angiotensin AT1 receptor blocker candesartan on myocardial ischemic/reperfusion injury.
Topics: Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Calcium | 1999 |
Cardioprotective effect of angiotensin-converting enzyme inhibition against hypoxia/reoxygenation injury in cultured rat cardiac myocytes.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti | 1999 |
Role of angiotensin in cardioprotective effect of ischemic preconditioning.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Coron | 1999 |
Combination of a calcium antagonist, a lipid-peroxidation inhibitor, and an angiotensin AT1-receptor antagonist provides additive myocardial infarct size-limiting effect in pigs.
Topics: Anesthesia; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Antioxidants; Benzim | 1999 |
Effects of the insurmountable angiotensin AT1 receptor antagonist candesartan and the surmountable antagonist losartan on ischemia/reperfusion injury in rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Creat | 1999 |
Effect of angiotensin converting enzyme inhibitor and angiotensin II type 1 receptor antagonist on metabolism and contraction in ischemia-reperfused rabbit heart.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2000 |
Cardioprotection induced by AT1R blockade after reperfused myocardial infarction: association with regional increase in AT2R, IP3R and PKCepsilon proteins and cGMP.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium Channels; Cyc | 2000 |
Role of cardiac ATP-sensitive K+ channels induced by angiotensin II type 1 receptor antagonist on metabolism, contraction and relaxation in ischemia-reperfused rabbit heart.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compoun | 2001 |
An angiotensin II type 1 receptor blocker, candesartan, increases myocardial apoptosis in rats with acute ischemia-reperfusion.
Topics: Acute Disease; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; bcl-2- | 2001 |
Cardioprotection with angiotensin converting enzyme inhibitor and angiotensin II type 1 receptor antagonist is not abolished by nitric oxide synthase inhibitor in ischemia-reperfused rabbit hearts.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; | 2001 |