candesartan has been researched along with Hypertrophy in 9 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated whether exaggerated BPV aggravates hypertensive cardiac remodeling and function by activating inflammation and angiotensin II-mediated mechanisms." | 7.75 | Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation. ( Anegawa, T; Hirooka, Y; Ikeda, A; Imaizumi, T; Kai, H; Kajimoto, H; Kato, S; Koga, M; Kudo, H; Mifune, H; Mori, T; Takayama, N; Yasuoka, S, 2009) |
| "The effects of CV-11974, a potent nonpeptide antagonist of the angiotensin II (AII) type-1 receptor (AT1), on cytosolic free calcium concentration ([Ca2+]i), hyperplasia, and hypertrophy of cultured vascular smooth muscle cells (VSMC) from rat aorta were studied." | 7.69 | Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells. ( Fukuo, K; Inoue, T; Jiang, B; Koh, E; Morimoto, S; Nabata, T; Ogihara, T; Rakugi, H; Tomita, J, 1994) |
| " We investigated whether exaggerated BPV aggravates hypertensive cardiac remodeling and function by activating inflammation and angiotensin II-mediated mechanisms." | 3.75 | Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation. ( Anegawa, T; Hirooka, Y; Ikeda, A; Imaizumi, T; Kai, H; Kajimoto, H; Kato, S; Koga, M; Kudo, H; Mifune, H; Mori, T; Takayama, N; Yasuoka, S, 2009) |
| "The effect of long-term administration of delapril, an angiotensin converting enzyme inhibitor, and candesartan, an angiotensin II receptor blocker, on cardiac hypertrophy was investigated in spontaneously hypertensive rats (SHR)." | 3.72 | Effect of an ACE inhibitor and an AT1 receptor antagonist on cardiac hypertrophy. ( Shikata, C; Takeda, A; Takeda, N, 2003) |
| "The effects of CV-11974, a potent nonpeptide antagonist of the angiotensin II (AII) type-1 receptor (AT1), on cytosolic free calcium concentration ([Ca2+]i), hyperplasia, and hypertrophy of cultured vascular smooth muscle cells (VSMC) from rat aorta were studied." | 3.69 | Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells. ( Fukuo, K; Inoue, T; Jiang, B; Koh, E; Morimoto, S; Nabata, T; Ogihara, T; Rakugi, H; Tomita, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishiguro, K | 1 |
| Hayashi, K | 1 |
| Sasamura, H | 1 |
| Sakamaki, Y | 1 |
| Itoh, H | 1 |
| Kudo, H | 1 |
| Kai, H | 1 |
| Kajimoto, H | 1 |
| Koga, M | 1 |
| Takayama, N | 1 |
| Mori, T | 1 |
| Ikeda, A | 1 |
| Yasuoka, S | 1 |
| Anegawa, T | 1 |
| Mifune, H | 1 |
| Kato, S | 1 |
| Hirooka, Y | 1 |
| Imaizumi, T | 1 |
| Susic, D | 1 |
| Varagic, J | 1 |
| Frohlich, ED | 1 |
| Shikata, C | 1 |
| Takeda, A | 1 |
| Takeda, N | 1 |
| Zhou, MS | 1 |
| Adam, AG | 1 |
| Jaimes, EA | 1 |
| Raij, L | 1 |
| Ando, H | 1 |
| Zhou, J | 1 |
| Macova, M | 1 |
| Imboden, H | 1 |
| Saavedra, JM | 1 |
| Madala Halagappa, VK | 1 |
| Tiwari, S | 1 |
| Riazi, S | 1 |
| Hu, X | 1 |
| Ecelbarger, CM | 1 |
| Koh, E | 1 |
| Morimoto, S | 1 |
| Tomita, J | 1 |
| Rakugi, H | 1 |
| Jiang, B | 1 |
| Inoue, T | 1 |
| Nabata, T | 1 |
| Fukuo, K | 1 |
| Ogihara, T | 1 |
| Fukuda, N | 1 |
| Satoh, C | 1 |
| Hu, WY | 1 |
| Soma, M | 1 |
| Kubo, A | 1 |
| Kishioka, H | 1 |
| Watanabe, Y | 1 |
| Izumi, Y | 1 |
| Kanmatsuse, K | 1 |
9 other studies available for candesartan and Hypertrophy
| Article | Year |
|---|---|
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2009 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; B | 2009 |
Cardiovascular effects of inhibition of renin-angiotensin-aldosterone system components in hypertensive rats given salt excess.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimid | 2010 |
Effect of an ACE inhibitor and an AT1 receptor antagonist on cardiac hypertrophy.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimid | 2003 |
In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Co | 2003 |
Angiotensin II AT1 receptor blockade reverses pathological hypertrophy and inflammation in brain microvessels of spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl | 2004 |
Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.
Topics: Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Bipheny | 2008 |
Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl | 1994 |
Production of angiotensin II by homogeneous cultures of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 1999 |