Page last updated: 2024-10-24

candesartan and Hyperplasia

candesartan has been researched along with Hyperplasia in 4 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"The effects of CV-11974, a potent nonpeptide antagonist of the angiotensin II (AII) type-1 receptor (AT1), on cytosolic free calcium concentration ([Ca2+]i), hyperplasia, and hypertrophy of cultured vascular smooth muscle cells (VSMC) from rat aorta were studied."7.69Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells. ( Fukuo, K; Inoue, T; Jiang, B; Koh, E; Morimoto, S; Nabata, T; Ogihara, T; Rakugi, H; Tomita, J, 1994)
"The effects of CV-11974, a potent nonpeptide antagonist of the angiotensin II (AII) type-1 receptor (AT1), on cytosolic free calcium concentration ([Ca2+]i), hyperplasia, and hypertrophy of cultured vascular smooth muscle cells (VSMC) from rat aorta were studied."3.69Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells. ( Fukuo, K; Inoue, T; Jiang, B; Koh, E; Morimoto, S; Nabata, T; Ogihara, T; Rakugi, H; Tomita, J, 1994)
"Candesartan treatment was associated with increased iNOS expression (p = ."2.84Support for involvement of the renin-angiotensin system in dysplastic Barrett's esophagus. ( Bratlie, SO; Casselbrant, A; Edebo, A; Fändriks, L, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bratlie, SO1
Casselbrant, A1
Edebo, A1
Fändriks, L1
Wakeyama, T1
Ogawa, H1
Iida, H1
Takaki, A1
Iwami, T1
Mochizuki, M1
Tanaka, T1
Koh, E1
Morimoto, S1
Tomita, J1
Rakugi, H1
Jiang, B1
Inoue, T1
Nabata, T1
Fukuo, K1
Ogihara, T1
Fukuda, N1
Satoh, C1
Hu, WY1
Soma, M1
Kubo, A1
Kishioka, H1
Watanabe, Y1
Izumi, Y1
Kanmatsuse, K1

Trials

2 trials available for candesartan and Hyperplasia

ArticleYear
Support for involvement of the renin-angiotensin system in dysplastic Barrett's esophagus.
    Scandinavian journal of gastroenterology, 2017, Volume: 52, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2017
Effects of candesartan and probucol on restenosis after coronary stenting: results of insight of stent intimal hyperplasia inhibition by new angiotensin II receptor antagonist (ISHIN) trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:6

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Anticholesteremic Agents; Benzimidazoles; Biphenyl Co

2003

Other Studies

2 other studies available for candesartan and Hyperplasia

ArticleYear
Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl

1994
Production of angiotensin II by homogeneous cultures of vascular smooth muscle cells from spontaneously hypertensive rats.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals;

1999